TreeWAS – Variant ID: rs10457441

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G20 Parkinson's disease	0.258	0.742	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.878	0.122
I73 Other peripheral vascular diseases	0.000	0.930	0.070
I73.8 Other specified peripheral vascular diseases	0.000	0.937	0.063
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.954	0.046
R22.2 Localised swelling, mass and lump, trunk	0.000	0.956	0.044
S01.8 Open wound of other parts of head	0.041	0.959	0.000
I73.0 Raynaud's syndrome	0.000	0.963	0.037
G20-G26 Extrapyramidal and movement disorders	0.035	0.965	0.000
S01.2 Open wound of nose	0.034	0.966	0.000
S01 Open wound of head	0.029	0.971	0.000
G21 Secondary Parkinsonism	0.029	0.971	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.973	0.027
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.025	0.975	0.000
G22 Parkinsonism in diseases classified elsewhere	0.025	0.975	0.000
G23 Other degenerative diseases of basal ganglia	0.024	0.975	0.000
S01.4 Open wound of cheek and temporomandibular area	0.024	0.976	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.976	0.024
G21.4 Vascular parkinsonism	0.022	0.978	0.000
G21.0 Malignant neuroleptic syndrome	0.022	0.978	0.000
G21.9 Secondary Parkinsonism, unspecified	0.022	0.978	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.022	0.978	0.000
G21.8 Other secondary Parkinsonism	0.021	0.979	0.000
G21.3 Postencephalitic Parkinsonism	0.021	0.979	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.021	0.979	0.000
I78 Diseases of capillaries	0.000	0.980	0.020
I77 Other disorders of arteries and arterioles	0.000	0.980	0.020
S01.3 Open wound of ear	0.019	0.981	0.000
S00-S09 Injuries to the head	0.019	0.981	0.000
S01.1 Open wound of eyelid and periocular area	0.019	0.981	0.000
S02.60 Fracture of mandible (closed)	0.019	0.981	0.000
I74 Arterial embolism and thrombosis	0.000	0.981	0.019
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.981	0.019
S02.6 Fracture of mandible	0.019	0.981	0.000
S02 Fracture of skull and facial bones	0.019	0.981	0.000
S06 Intracranial injury	0.018	0.982	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.982	0.018
I77.6 Arteritis, unspecified	0.000	0.982	0.018
G23.9 Degenerative disease of basal ganglia, unspecified	0.018	0.982	0.000
G23.3 Multiple system atrophy, cerebellar type	0.018	0.982	0.000
G23.2 Striatonigral degeneration	0.018	0.982	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.018	0.982	0.000
G23.0 Hallervorden-Spatz disease	0.018	0.982	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.982	0.018
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.983	0.017
G23.8 Other specified degenerative diseases of basal ganglia	0.017	0.983	0.000
S06.2 Diffuse brain injury	0.017	0.983	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.983	0.017
S01.5 Open wound of lip and oral cavity	0.017	0.983	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.016	0.984	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.984	0.016
S06.20 Diffuse brain injury (without open intracranial wound)	0.016	0.984	0.000
S02.0 Fracture of vault of skull	0.016	0.984	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.016	0.984	0.000
I78.8 Other diseases of capillaries	0.000	0.984	0.016
S06.0 Concussion	0.016	0.984	0.000
I70 Atherosclerosis	0.000	0.985	0.015
I74.8 Embolism and thrombosis of other arteries	0.000	0.985	0.015
S06.9 Intracranial injury, unspecified	0.014	0.986	0.000
S02.5 Fracture of tooth	0.014	0.986	0.000
S02.8 Fractures of other skull and facial bones	0.014	0.986	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.986	0.014
S02.00 Fracture of vault of skull (closed)	0.014	0.986	0.000
I77.5 Necrosis of artery	0.000	0.986	0.014
I77.4 Coeliac artery compression syndrome	0.000	0.986	0.014
I77.3 Arterial fibromuscular dysplasia	0.000	0.986	0.014
S06.1 Traumatic cerebral oedema	0.014	0.986	0.000
S07 Crushing injury of head	0.014	0.986	0.000
S04 Injury of cranial nerves	0.014	0.986	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.986	0.014
S08 Traumatic amputation of part of head	0.014	0.986	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.014	0.986	0.000
S02.3 Fracture of orbital floor	0.014	0.986	0.000
S06.00 Concussion (without open intracranial wound)	0.014	0.986	0.000
S02.61 Fracture of mandible (open)	0.014	0.986	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.014	0.986	0.000
I72 Other aneurysm	0.000	0.986	0.014
S03.1 Dislocation of septal cartilage of nose	0.013	0.986	0.000
S02.7 Multiple fractures involving skull and facial bones	0.013	0.987	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.987	0.013
S06.8 Other intracranial injuries	0.013	0.987	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.987	0.013
S06.7 Intracranial injury with prolonged coma	0.013	0.987	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.987	0.013
S01.0 Open wound of scalp	0.013	0.987	0.000
S05 Injury of eye and orbit	0.013	0.987	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.987	0.013
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.987	0.013
I79.1 Aortitis in diseases classified elsewhere	0.000	0.987	0.013
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.987	0.013
S06.4 Epidural haemorrhage	0.013	0.987	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.987	0.013
S03.0 Dislocation of jaw	0.013	0.987	0.000
S06.5 Traumatic subdural haemorrhage	0.013	0.987	0.000
S03.2 Dislocation of tooth	0.012	0.987	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.012	0.988	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.988	0.012
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.012	0.988	0.000
S03.4 Sprain and strain of jaw	0.012	0.988	0.000
S03.3 Dislocation of other and unspecified parts of head	0.012	0.988	0.000
I77.2 Rupture of artery	0.000	0.988	0.012
S02.01 Fracture of vault of skull (open)	0.012	0.988	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.012	0.988	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.988	0.012
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.012	0.988	0.000
I78.1 Naevus, nonneoplastic	0.000	0.988	0.012
I72.4 Aneurysm of artery of lower extremity	0.000	0.988	0.012
I70.0 Atherosclerosis of aorta	0.000	0.988	0.011
S06.01 Concussion (with open intracranial wound)	0.011	0.989	0.000
S02.50 Fracture of tooth (closed)	0.011	0.989	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.011	0.989	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.011	0.989	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.989	0.011
I70.8 Atherosclerosis of other arteries	0.000	0.989	0.011
I72.2 Aneurysm of renal artery	0.000	0.989	0.011
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.011	0.989	0.000
I72.3 Aneurysm of iliac artery	0.000	0.989	0.011
S02.51 Fracture of tooth (open)	0.010	0.989	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.010	0.989	0.000
S02.81 Fractures of other skull and facial bones (open)	0.010	0.989	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.011	0.989	0.000
S01.7 Multiple open wounds of head	0.010	0.989	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.010	0.989	0.000
C50.8 Overlapping lesion of breast	0.000	0.989	0.011
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.010	0.990	0.000
S04.9 Injury of unspecified cranial nerve	0.010	0.990	0.000
S04.8 Injury of other cranial nerves	0.010	0.990	0.000
S04.7 Injury of accessory nerve	0.010	0.990	0.000
S04.6 Injury of acoustic nerve	0.010	0.990	0.000
S04.5 Injury of facial nerve	0.010	0.990	0.000
S04.4 Injury of abducent nerve	0.010	0.990	0.000
S04.3 Injury of trigeminal nerve	0.010	0.990	0.000
S04.2 Injury of trochlear nerve	0.010	0.990	0.000
S04.1 Injury of oculomotor nerve	0.010	0.990	0.000
S04.0 Injury of optic nerve and pathways	0.010	0.990	0.000
S07.9 Crushing injury of head, part unspecified	0.010	0.990	0.000
S07.8 Crushing injury of other parts of head	0.010	0.990	0.000
S07.1 Crushing injury of skull	0.010	0.990	0.000
S07.0 Crushing injury of face	0.010	0.990	0.000
S02.1 Fracture of base of skull	0.010	0.990	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.010	0.990	0.000
I72.1 Aneurysm of artery of upper extremity	0.000	0.990	0.010
S02.2 Fracture of nasal bones	0.010	0.990	0.000
S02.30 Fracture of orbital floor (closed)	0.010	0.990	0.000
S08.9 Traumatic amputation of unspecified part of head	0.010	0.990	0.000
S08.8 Traumatic amputation of other parts of head	0.010	0.990	0.000
S08.0 Avulsion of scalp	0.010	0.990	0.000
S02.4 Fracture of malar and maxillary bones	0.010	0.990	0.000
S02.31 Fracture of orbital floor (open)	0.010	0.990	0.000
S05.9 Injury of eye and orbit, part unspecified	0.010	0.990	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.010	0.990	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.990	0.010
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.990	0.010
S08.1 Traumatic amputation of ear	0.010	0.990	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.010	0.990	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.010	0.990	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.010	0.990	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.010	0.990	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.010	0.990	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.010	0.990	0.000
S06.3 Focal brain injury	0.010	0.990	0.000
S05.7 Avulsion of eye	0.010	0.990	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.010	0.990	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.009	0.991	0.000
G24 Dystonia	0.009	0.991	0.001
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.009	0.991	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.009	0.991	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.991	0.009
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.009	0.991	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.991	0.009
S09 Other and unspecified injuries of head	0.009	0.991	0.000
G25 Other extrapyramidal and movement disorders	0.009	0.991	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.009	0.991	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.991	0.009
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.991	0.008
I72.9 Aneurysm of unspecified site	0.000	0.991	0.008
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.008	0.991	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.991	0.008
L81.4 Other melanin hyperpigmentation	0.000	0.992	0.008
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.992	0.008
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.992	0.008
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.992	0.008
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.992	0.008
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.992	0.008
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.992	0.008
S02.11 Fracture of base of skull (open)	0.008	0.992	0.000
S02.21 Fracture of nasal bones (open)	0.008	0.992	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.007	0.992	0.000
S05.8 Other injuries of eye and orbit	0.008	0.992	0.000
D52 Folate deficiency anaemia	0.000	0.992	0.008
G25.5 Other chorea	0.007	0.992	0.000
S09.9 Unspecified injury of head	0.007	0.993	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.007	0.993	0.000
I72.0 Aneurysm of carotid artery	0.000	0.993	0.007
G24.0 Drug-induced dystonia	0.007	0.993	0.001
S05.1 Contusion of eyeball and orbital tissues	0.007	0.993	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.007	0.993	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.993	0.007
G24.4 Idiopathic orofacial dystonia	0.006	0.993	0.001
G24.2 Idiopathic nonfamilial dystonia	0.006	0.993	0.001
G24.1 Idiopathic familial dystonia	0.006	0.993	0.001
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.993	0.007
S09.7 Multiple injuries of head	0.007	0.993	0.000
S09.1 Injury of muscle and tendon of head	0.007	0.993	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.993	0.007
G25.6 Drug-induced tics and other tics of organic origin	0.006	0.993	0.000
G25.4 Drug-induced chorea	0.006	0.993	0.000
S09.2 Traumatic rupture of ear drum	0.006	0.993	0.000
G25.1 Drug-induced tremor	0.006	0.993	0.000
G25.3 Myoclonus	0.006	0.994	0.000
G25.2 Other specified forms of tremor	0.006	0.994	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.994	0.006
G24.9 Dystonia, unspecified	0.006	0.994	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.006	0.994	0.000
I77.1 Stricture of artery	0.000	0.994	0.006
G25.0 Essential tremor	0.006	0.994	0.000
D52.8 Other folate deficiency anaemias	0.000	0.994	0.006
D52.1 Drug-induced folate deficiency anaemia	0.000	0.994	0.006
D52.0 Dietary folate deficiency anaemia	0.000	0.994	0.006
D05.1 Intraductal carcinoma in situ	0.006	0.994	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.005	0.994	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.995	0.005
G24.5 Blepharospasm	0.005	0.995	0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.995	0.005
G24.3 Spasmodic torticollis	0.004	0.995	0.001
D86.9 Sarcoidosis, unspecified	0.000	0.995	0.005
C91.1 Chronic lymphocytic leukaemia	0.005	0.995	0.000
D86.0 Sarcoidosis of lung	0.000	0.995	0.005
H93.1 Tinnitus	0.000	0.995	0.005
E78.4 Other hyperlipidaemia	0.000	0.995	0.005
G25.9 Extrapyramidal and movement disorder, unspecified	0.004	0.995	0.001
E78.6 Lipoprotein deficiency	0.000	0.995	0.005
E78.3 Hyperchylomicronaemia	0.000	0.995	0.004
D86 Sarcoidosis	0.000	0.995	0.005
G24.8 Other dystonia	0.003	0.995	0.001
E78.8 Other disorders of lipoprotein metabolism	0.000	0.995	0.004
K42 Umbilical hernia	0.000	0.995	0.004
N60.2 Fibroadenosis of breast	0.000	0.996	0.004
S61.1 Open wound of finger(s) with damage to nail	0.000	0.996	0.004
I72.8 Aneurysm of other specified arteries	0.001	0.996	0.004
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.996	0.004
H65.0 Acute serous otitis media	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.000	0.996	0.004
H65 Nonsuppurative otitis media	0.000	0.996	0.004
I71 Aortic aneurysm and dissection	0.000	0.996	0.004
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.996	0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
S02.40 Fracture of malar and maxillary bones (closed)	0.004	0.996	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.996	0.001
D86.1 Sarcoidosis of lymph nodes	0.000	0.996	0.004
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.004	0.996	0.000
S01.9 Open wound of head, part unspecified	0.003	0.996	0.001
S09.8 Other specified injuries of head	0.003	0.996	0.001
T78.2 Anaphylactic shock, unspecified	0.000	0.996	0.004
T78 Adverse effects, not elsewhere classified	0.000	0.996	0.004
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.000	0.997	0.003
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.003
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.997	0.003
I71.0 Dissection of aorta [any part]	0.003	0.997	0.001
E61.1 Iron deficiency	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.997	0.003
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.997	0.003
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.997	0.003
H93 Other disorders of ear, not elsewhere classified	0.000	0.997	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.997	0.003
E78.1 Pure hyperglyceridaemia	0.000	0.997	0.003
K42.1 Umbilical hernia with gangrene	0.000	0.997	0.003
E78.2 Mixed hyperlipidaemia	0.000	0.997	0.003
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.997	0.003
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.003
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.997	0.003
H93.8 Other specified disorders of ear	0.000	0.997	0.003
F30.0 Hypomania	0.003	0.997	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
F31 Bipolar affective disorder	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.997	0.003
I49.9 Cardiac arrhythmia, unspecified	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
L81 Other disorders of pigmentation	0.000	0.997	0.002
Q23 Congenital malformations of aortic and mitral valves	0.000	0.997	0.003
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.003	0.997	0.000
R44.0 Auditory hallucinations	0.003	0.997	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.997	0.003
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
H65.2 Chronic serous otitis media	0.000	0.997	0.003
Q23.0 Congenital stenosis of aortic valve	0.000	0.997	0.003
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.003	0.997	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
E87.3 Alkalosis	0.000	0.997	0.003
L81.2 Freckles	0.000	0.997	0.002
D05.7 Other carcinoma in situ of breast	0.003	0.997	0.000
R44.3 Hallucinations, unspecified	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
Z22 Carrier of infectious disease	0.000	0.997	0.003
H93.0 Degenerative and vascular disorders of ear	0.000	0.997	0.002
D05 Carcinoma in situ of breast	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.002
H93.3 Disorders of acoustic nerve	0.000	0.997	0.002
I24.9 Acute ischaemic heart disease, unspecified	0.003	0.997	0.000
J81 Pulmonary oedema	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.000	0.998	0.002
N18.0 End-stage renal disease	0.000	0.998	0.002
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
L81.6 Other disorders of diminished melanin formation	0.000	0.998	0.002
L81.5 Leukoderma, not elsewhere classified	0.000	0.998	0.002
L81.3 Cafe au lait spots	0.000	0.998	0.002
L81.1 Chloasma	0.000	0.998	0.002
N17.9 Acute renal failure, unspecified	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.002
Q23.2 Congenital mitral stenosis	0.000	0.998	0.002
R44.2 Other hallucinations	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.998	0.002
L81.7 Pigmented purpuric dermatosis	0.000	0.998	0.002
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
R44.1 Visual hallucinations	0.002	0.998	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.998	0.002
M10.9 Gout, unspecified	0.000	0.998	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.002	0.998	0.000
M10.90 Gout, unspecified (Multiple sites)	0.000	0.998	0.002
L81.0 Postinflammatory hyperpigmentation	0.000	0.998	0.002
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.000	0.998	0.002
Z22.9 Carrier of infectious disease, unspecified	0.000	0.998	0.002
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.998	0.002
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.998	0.002
Z22.2 Carrier of diphtheria	0.000	0.998	0.002
Z22.0 Carrier of typhoid	0.000	0.998	0.002
E87.5 Hyperkalaemia	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
L81.8 Other specified disorders of pigmentation	0.000	0.998	0.002
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.001	0.998	0.001
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
M25.72 Osteophyte (Upper arm)	0.002	0.998	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.998	0.002
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.002	0.998	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
H66 Suppurative and unspecified otitis media	0.000	0.998	0.002
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
H93.9 Disorder of ear, unspecified	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.998	0.001
J31.0 Chronic rhinitis	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
Z22.8 Carrier of other infectious diseases	0.000	0.998	0.002
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.002	0.998	0.000
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
L80 Vitiligo	0.002	0.998	0.000
M10.98 Gout, unspecified (Other)	0.000	0.998	0.002
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M10.91 Gout, unspecified (Shoulder region)	0.000	0.998	0.002
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.002
M10.92 Gout, unspecified (Upper arm)	0.000	0.998	0.002
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.002	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.002	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.002	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.002	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
Z43.2 Attention to ileostomy	0.000	0.998	0.002
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
L92.0 Granuloma annulare	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.001	0.998	0.000
W17.6 Industrial and construction area	0.000	0.998	0.002
L84 Corns and callosities	0.002	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
C91 Lymphoid leukaemia	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.998	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
M21.0 Valgus deformity, not elsewhere classified	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
M33.2 Polymyositis	0.002	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.001	0.998	0.000
M66.1 Rupture of synovium	0.001	0.998	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.998	0.002
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.001
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.001
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.001
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.001
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
F41.1 Generalised anxiety disorder	0.000	0.998	0.002
J39.2 Other diseases of pharynx	0.002	0.998	0.000
K10.3 Alveolitis of jaws	0.000	0.998	0.002
S27.3 Other injuries of lung	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
K41 Femoral hernia	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
M33.1 Other dermatomyositis	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.001	0.998	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.998	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.001	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.001	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.001	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.001	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.001	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.001	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.001	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.001
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.001
I62.1 Nontraumatic extradural haemorrhage	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations