TreeWAS – Variant ID: rs10496964

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F30-F39 Mood [affective] disorders	0.721	0.279	0.000
F31 Bipolar affective disorder	0.720	0.280	0.000
F32 Depressive episode	0.705	0.295	0.000
F60-F69 Disorders of adult personality and behaviour	0.676	0.324	0.000
F60 Specific personality disorders	0.673	0.327	0.000
Chapter V Mental and behavioural disorders	0.671	0.329	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.668	0.332	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.660	0.340	0.000
F60.9 Personality disorder, unspecified	0.638	0.362	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.630	0.370	0.000
F33 Recurrent depressive disorder	0.623	0.377	0.000
F69 Unspecified disorder of adult personality and behaviour	0.621	0.379	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.608	0.392	0.000
F31.7 Bipolar affective disorder, currently in remission	0.598	0.402	0.000
F32.0 Mild depressive episode	0.595	0.405	0.000
F60.3 Emotionally unstable personality disorder	0.595	0.405	0.000
F32.1 Moderate depressive episode	0.591	0.409	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.584	0.416	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.577	0.423	0.000
F34 Persistent mood [affective] disorders	0.573	0.427	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.570	0.430	0.000
F99-F99 Unspecified mental disorder	0.566	0.434	0.000
F60.7 Dependent personality disorder	0.564	0.436	0.000
F31.8 Other bipolar affective disorders	0.558	0.442	0.000
F60.5 Anankastic personality disorder	0.553	0.447	0.000
F32.9 Depressive episode, unspecified	0.553	0.447	0.000
F70-F79 Mental retardation	0.553	0.447	0.000
F32.8 Other depressive episodes	0.550	0.450	0.000
F60.2 Dissocial personality disorder	0.548	0.452	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.526	0.474	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.525	0.475	0.000
F39 Unspecified mood [affective] disorder	0.519	0.481	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.518	0.482	0.000
F38 Other mood [affective] disorders	0.517	0.483	0.000
F64 Gender identity disorders	0.502	0.498	0.000
F99 Mental disorder, not otherwise specified	0.490	0.509	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.486	0.514	0.000
F68 Other disorders of adult personality and behaviour	0.485	0.515	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.485	0.515	0.000
F65 Disorders of sexual preference	0.485	0.515	0.000
F63 Habit and impulse disorders	0.485	0.515	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.485	0.515	0.000
F61 Mixed and other personality disorders	0.485	0.515	0.000
F60.8 Other specific personality disorders	0.483	0.517	0.000
F60.6 Anxious [avoidant] personality disorder	0.483	0.517	0.000
F60.4 Histrionic personality disorder	0.483	0.517	0.000
F60.1 Schizoid personality disorder	0.483	0.517	0.000
F60.0 Paranoid personality disorder	0.483	0.517	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.481	0.519	0.000
F33.9 Recurrent depressive disorder, unspecified	0.480	0.520	0.000
F80-F89 Disorders of psychological development	0.473	0.527	0.000
F31.9 Bipolar affective disorder, unspecified	0.471	0.529	0.000
F79 Unspecified mental retardation	0.468	0.532	0.000
F34.1 Dysthymia	0.467	0.533	0.000
F30 Manic episode	0.465	0.535	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.463	0.537	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.458	0.542	0.000
F33.8 Other recurrent depressive disorders	0.447	0.553	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.447	0.553	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.438	0.562	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.437	0.563	0.000
F50 Eating disorders	0.430	0.570	0.000
F52.2 Failure of genital response	0.426	0.574	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.411	0.589	0.000
F34.8 Other persistent mood [affective] disorders	0.411	0.589	0.000
F34.0 Cyclothymia	0.411	0.589	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.409	0.591	0.000
F51 Nonorganic sleep disorders	0.409	0.591	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.409	0.591	0.000
F55 Abuse of non-dependence-producing substances	0.409	0.591	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.409	0.591	0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)	0.408	0.592	0.000
F78 Other mental retardation	0.396	0.603	0.000
F73 Profound mental retardation	0.396	0.603	0.000
F72 Severe mental retardation	0.396	0.603	0.000
F71 Moderate mental retardation	0.396	0.603	0.000
F70 Mild mental retardation	0.396	0.603	0.000
F64.0 Transsexualism	0.377	0.623	0.000
F80 Specific developmental disorders of speech and language	0.377	0.623	0.000
F38.8 Other specified mood [affective] disorders	0.371	0.629	0.000
F38.1 Other recurrent mood [affective] disorders	0.371	0.629	0.000
F38.0 Other single mood [affective] disorders	0.371	0.629	0.000
F64.9 Gender identity disorder, unspecified	0.360	0.640	0.000
F64.8 Other gender identity disorders	0.360	0.640	0.000
F64.2 Gender identity disorder of childhood	0.360	0.640	0.000
F64.1 Dual-role transvestism	0.360	0.640	0.000
F30.9 Manic episode, unspecified	0.355	0.645	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.349	0.651	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.349	0.651	0.000
F52.7 Excessive sexual drive	0.349	0.651	0.000
F52.6 Nonorganic dyspareunia	0.349	0.651	0.000
F52.5 Nonorganic vaginismus	0.349	0.651	0.000
F52.4 Premature ejaculation	0.349	0.651	0.000
F52.3 Orgasmic dysfunction	0.349	0.651	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.349	0.651	0.000
F52.0 Lack or loss of sexual desire	0.349	0.651	0.000
F62.9 Enduring personality change, unspecified	0.347	0.652	0.000
F62.8 Other enduring personality changes	0.347	0.652	0.000
F62.1 Enduring personality change after psychiatric illness	0.347	0.652	0.000
F62.0 Enduring personality change after catastrophic experience	0.347	0.652	0.000
F63.9 Habit and impulse disorder, unspecified	0.347	0.652	0.000
F63.8 Other habit and impulse disorders	0.347	0.652	0.000
F63.3 Trichotillomania	0.347	0.652	0.000
F63.2 Pathological stealing [kleptomania]	0.347	0.652	0.000
F63.1 Pathological fire-setting [pyromania]	0.347	0.652	0.000
F63.0 Pathological gambling	0.347	0.652	0.000
F65.9 Disorder of sexual preference, unspecified	0.347	0.652	0.000
F65.8 Other disorders of sexual preference	0.347	0.652	0.000
F65.6 Multiple disorders of sexual preference	0.347	0.652	0.000
F65.5 Sadomasochism	0.347	0.652	0.000
F65.4 Paedophilia	0.347	0.652	0.000
F65.3 Voyeurism	0.347	0.652	0.000
F65.2 Exhibitionism	0.347	0.652	0.000
F65.1 Fetishistic transvestism	0.347	0.652	0.000
F65.0 Fetishism	0.347	0.652	0.000
F66.9 Psychosexual development disorder, unspecified	0.347	0.652	0.000
F66.8 Other psychosexual development disorders	0.347	0.652	0.000
F66.2 Sexual relationship disorder	0.347	0.652	0.000
F66.1 Egodystonic sexual orientation	0.347	0.652	0.000
F66.0 Sexual maturation disorder	0.347	0.652	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.347	0.652	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.347	0.652	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.347	0.652	0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.345	0.655	0.000
F95 Tic disorders	0.345	0.655	0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.345	0.655	0.000
F93 Emotional disorders with onset specific to childhood	0.345	0.655	0.000
F92 Mixed disorders of conduct and emotions	0.345	0.655	0.000
F91 Conduct disorders	0.345	0.655	0.000
F90 Hyperkinetic disorders	0.345	0.655	0.000
F89 Unspecified disorder of psychological development	0.339	0.661	0.000
F88 Other disorders of psychological development	0.339	0.661	0.000
F83 Mixed specific developmental disorders	0.339	0.661	0.000
F82 Specific developmental disorder of motor function	0.339	0.661	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.337	0.663	0.000
F79.8 Unspecified mental retardation (Other impairments of behaviour)	0.336	0.664	0.000
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.336	0.664	0.000
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.336	0.664	0.000
F30.8 Other manic episodes	0.333	0.667	0.000
F30.1 Mania without psychotic symptoms	0.333	0.667	0.000
F50.9 Eating disorder, unspecified	0.333	0.667	0.000
F84 Pervasive developmental disorders	0.319	0.680	0.000
F50.0 Anorexia nervosa	0.318	0.682	0.000
F30.2 Mania with psychotic symptoms	0.312	0.687	0.000
F80.1 Expressive language disorder	0.309	0.691	0.000
F50.8 Other eating disorders	0.308	0.691	0.000
F50.5 Vomiting associated with other psychological disturbances	0.308	0.691	0.000
F50.4 Overeating associated with other psychological disturbances	0.308	0.691	0.000
F50.3 Atypical bulimia nervosa	0.308	0.691	0.000
F50.1 Atypical anorexia nervosa	0.308	0.691	0.000
F22 Persistent delusional disorders	0.305	0.695	0.000
F81 Specific developmental disorders of scholastic skills	0.299	0.701	0.000
F50.2 Bulimia nervosa	0.295	0.705	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.293	0.707	0.000
F51.8 Other nonorganic sleep disorders	0.293	0.707	0.000
F51.5 Nightmares	0.293	0.707	0.000
F51.4 Sleep terrors [night terrors]	0.293	0.707	0.000
F51.3 Sleepwalking [somnambulism]	0.293	0.707	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.293	0.707	0.000
F51.1 Nonorganic hypersomnia	0.293	0.707	0.000
F51.0 Nonorganic insomnia	0.293	0.707	0.000
F53.9 Puerperal mental disorder, unspecified	0.293	0.707	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.293	0.707	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.293	0.707	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.293	0.707	0.000
F70.9 Mild mental retardation (Without mention of impairment of behaviour)	0.284	0.715	0.000
F70.8 Mild mental retardation (Other impairments of behaviour)	0.284	0.715	0.000
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.284	0.715	0.000
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.284	0.715	0.000
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)	0.284	0.715	0.000
F71.8 Moderate mental retardation (Other impairments of behaviour)	0.284	0.715	0.000
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.284	0.715	0.000
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.284	0.715	0.000
F72.9 Severe mental retardation (Without mention of impairment of behaviour)	0.284	0.715	0.000
F72.8 Severe mental retardation (Other impairments of behaviour)	0.284	0.715	0.000
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.284	0.715	0.000
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.284	0.715	0.000
F73.9 Profound mental retardation (Without mention of impairment of behaviour)	0.284	0.715	0.000
F73.8 Profound mental retardation (Other impairments of behaviour)	0.284	0.715	0.000
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.284	0.715	0.000
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.284	0.715	0.000
F78.9 Other mental retardation (Without mention of impairment of behaviour)	0.284	0.715	0.000
F78.8 Other mental retardation (Other impairments of behaviour)	0.284	0.715	0.000
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.284	0.715	0.000
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.284	0.715	0.000
F22.0 Delusional disorder	0.283	0.717	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.280	0.720	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.275	0.725	0.000
F30.0 Hypomania	0.274	0.726	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.270	0.729	0.000
F80.8 Other developmental disorders of speech and language	0.270	0.729	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.270	0.729	0.000
F80.2 Receptive language disorder	0.270	0.729	0.000
F80.0 Specific speech articulation disorder	0.270	0.729	0.000
T43.2 Other and unspecified antidepressants	0.270	0.730	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.264	0.736	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.261	0.739	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.258	0.742	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.252	0.748	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.250	0.750	0.000
F23 Acute and transient psychotic disorders	0.249	0.751	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.249	0.751	0.000
F90.9 Hyperkinetic disorder, unspecified	0.247	0.752	0.000
F90.8 Other hyperkinetic disorders	0.247	0.752	0.000
F90.1 Hyperkinetic conduct disorder	0.247	0.752	0.000
F90.0 Disturbance of activity and attention	0.247	0.752	0.000
F91.9 Conduct disorder, unspecified	0.247	0.752	0.000
F91.8 Other conduct disorders	0.247	0.752	0.000
F91.3 Oppositional defiant disorder	0.247	0.752	0.000
F91.2 Socialised conduct disorder	0.247	0.752	0.000
F91.1 Unsocialised conduct disorder	0.247	0.752	0.000
F91.0 Conduct disorder confined to the family context	0.247	0.752	0.000
F92.9 Mixed disorder of conduct and emotions, unspecified	0.247	0.752	0.000
F92.8 Other mixed disorders of conduct and emotions	0.247	0.752	0.000
F92.0 Depressive conduct disorder	0.247	0.752	0.000
F93.9 Childhood emotional disorder, unspecified	0.247	0.752	0.000
F93.8 Other childhood emotional disorders	0.247	0.752	0.000
F93.3 Sibling rivalry disorder	0.247	0.752	0.000
F93.2 Social anxiety disorder of childhood	0.247	0.752	0.000
F93.1 Phobic anxiety disorder of childhood	0.247	0.752	0.000
F93.0 Separation anxiety disorder of childhood	0.247	0.752	0.000
F94.9 Childhood disorder of social functioning, unspecified	0.247	0.752	0.000
F94.8 Other childhood disorders of social functioning	0.247	0.752	0.000
F94.2 Disinhibited attachment disorder of childhood	0.247	0.752	0.000
F94.1 Reactive attachment disorder of childhood	0.247	0.752	0.000
F94.0 Elective mutism	0.247	0.752	0.000
F95.9 Tic disorder, unspecified	0.247	0.752	0.000
F95.8 Other tic disorders	0.247	0.752	0.000
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]	0.247	0.752	0.000
F95.1 Chronic motor or vocal tic disorder	0.247	0.752	0.000
F95.0 Transient tic disorder	0.247	0.752	0.000
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.247	0.752	0.000
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.247	0.752	0.000
F98.6 Cluttering	0.247	0.752	0.000
F98.5 Stuttering [stammering]	0.247	0.752	0.000
F98.4 Stereotyped movement disorders	0.247	0.752	0.000
F98.3 Pica of infancy and childhood	0.247	0.752	0.000
F98.2 Feeding disorder of infancy and childhood	0.247	0.752	0.000
F98.1 Nonorganic encopresis	0.247	0.752	0.000
F98.0 Nonorganic enuresis	0.247	0.752	0.000
F28 Other nonorganic psychotic disorders	0.242	0.758	0.000
F24 Induced delusional disorder	0.242	0.758	0.000
F21 Schizotypal disorder	0.242	0.758	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.240	0.760	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.236	0.764	0.000
F84.9 Pervasive developmental disorder, unspecified	0.229	0.771	0.000
F84.8 Other pervasive developmental disorders	0.229	0.771	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.229	0.771	0.000
F84.3 Other childhood disintegrative disorder	0.229	0.771	0.000
F84.2 Rett's syndrome	0.229	0.771	0.000
F84.1 Atypical autism	0.229	0.771	0.000
F84.0 Childhood autism	0.229	0.771	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.227	0.773	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.224	0.776	0.000
T42.4 Benzodiazepines	0.220	0.780	0.000
F22.9 Persistent delusional disorder, unspecified	0.219	0.781	0.000
F22.8 Other persistent delusional disorders	0.219	0.781	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.216	0.784	0.000
F81.8 Other developmental disorders of scholastic skills	0.215	0.785	0.000
F81.3 Mixed disorder of scholastic skills	0.215	0.785	0.000
F81.2 Specific disorder of arithmetical skills	0.215	0.785	0.000
F81.1 Specific spelling disorder	0.215	0.785	0.000
F81.0 Specific reading disorder	0.215	0.785	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.213	0.787	0.000
F84.5 Asperger's syndrome	0.210	0.790	0.000
F43 Reaction to severe stress, and adjustment disorders	0.207	0.793	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.206	0.794	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.206	0.794	0.000
N20.1 Calculus of ureter	0.203	0.797	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.203	0.797	0.000
T43.6 Psychostimulants with abuse potential	0.202	0.798	0.000
T43.9 Psychotropic drug, unspecified	0.201	0.799	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.201	0.799	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.200	0.800	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.199	0.801	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.199	0.801	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.197	0.803	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.197	0.803	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.196	0.804	0.000
T42.0 Hydantoin derivatives	0.190	0.810	0.000
F43.0 Acute stress reaction	0.189	0.811	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.189	0.811	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.189	0.811	0.000
T42.3 Barbiturates	0.189	0.811	0.000
T42.2 Succinimides and oxazolidinediones	0.189	0.811	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.186	0.814	0.000
T50.4 Drugs affecting uric acid metabolism	0.185	0.815	0.000
T50.8 Diagnostic agents	0.185	0.815	0.000
T50.7 Analeptics and opioid receptor antagonists	0.185	0.815	0.000
T50.5 Appetite depressants	0.185	0.815	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.185	0.815	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.185	0.815	0.000
T50.1 Loop [high-ceiling] diuretics	0.185	0.815	0.000
T50.0 Mineralocorticoids and their antagonists	0.185	0.815	0.000
T42.1 Iminostilbenes	0.184	0.816	0.000
T36 Poisoning by systemic antibiotics	0.183	0.817	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.183	0.817	0.000
T47.2 Stimulant laxatives	0.183	0.817	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.179	0.821	0.000
F23.8 Other acute and transient psychotic disorders	0.179	0.821	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.179	0.821	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.179	0.821	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.179	0.821	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.179	0.821	0.000
F40 Phobic anxiety disorders	0.178	0.822	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.178	0.822	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.176	0.823	0.000
T38.1 Thyroid hormones and substitutes	0.175	0.824	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.175	0.825	0.000
F44 Dissociative [conversion] disorders	0.174	0.825	0.000
T39.0 Salicylates	0.174	0.826	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.173	0.827	0.000
T38.9 Other and unspecified hormone antagonists	0.169	0.830	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.169	0.830	0.000
T38.7 Androgens and anabolic congeners	0.169	0.830	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.169	0.830	0.000
T38.5 Other oestrogens and progestogens	0.169	0.830	0.000
T38.4 Oral contraceptives	0.169	0.830	0.000
T38.2 Antithyroid drugs	0.169	0.830	0.000
T38.0 Glucocorticoids and synthetic analogues	0.169	0.830	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.163	0.837	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.163	0.837	0.000
T47.7 Emetics	0.163	0.837	0.000
T47.6 Antidiarrhoeal drugs	0.163	0.837	0.000
T47.5 Digestants	0.163	0.837	0.000
T47.4 Other laxatives	0.163	0.837	0.000
T47.3 Saline and osmotic laxatives	0.163	0.837	0.000
T47.0 Histamine H(2)-receptor antagonists	0.163	0.837	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.163	0.837	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.161	0.839	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.161	0.839	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.161	0.839	0.000
F43.2 Adjustment disorders	0.159	0.841	0.000
F29 Unspecified nonorganic psychosis	0.158	0.842	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.157	0.843	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.156	0.844	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.155	0.845	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.155	0.845	0.000
F42 Obsessive-compulsive disorder	0.155	0.845	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.155	0.845	0.000
T48.5 Anti-common-cold drugs	0.155	0.845	0.000
T48.4 Expectorants	0.155	0.845	0.000
T48.3 Antitussives	0.155	0.845	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.155	0.845	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.155	0.845	0.000
T48.0 Oxytocic drugs	0.155	0.845	0.000
F48 Other neurotic disorders	0.154	0.846	0.000
F40.9 Phobic anxiety disorder, unspecified	0.152	0.848	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.151	0.849	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.151	0.849	0.000
F11 Mental and behavioural disorders due to use of opioids	0.150	0.850	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.149	0.850	0.000
F43.8 Other reactions to severe stress	0.148	0.852	0.000
F13.2 Dependence syndrome	0.147	0.853	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.146	0.854	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.146	0.854	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.146	0.854	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.146	0.854	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.146	0.854	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.146	0.854	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.146	0.854	0.000
T44.0 Anticholinesterase agents	0.146	0.854	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.145	0.855	0.000
F40.8 Other phobic anxiety disorders	0.145	0.855	0.000
T39.4 Antirheumatics, not elsewhere classified	0.144	0.856	0.000
T39.2 Pyrazolone derivatives	0.144	0.856	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.143	0.857	0.000
T37.5 Antiviral drugs	0.143	0.857	0.000
T37.4 Anthelminthics	0.143	0.857	0.000
T37.3 Other antiprotozoal drugs	0.143	0.857	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.143	0.857	0.000
T37.1 Antimycobacterial drugs	0.143	0.857	0.000
T37.0 Sulphonamides	0.143	0.857	0.000
F25 Schizoaffective disorders	0.142	0.857	0.001
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.142	0.858	0.000
T41.5 Therapeutic gases	0.142	0.858	0.000
T41.4 Anaesthetic, unspecified	0.142	0.858	0.000
T41.3 Local anaesthetics	0.142	0.858	0.000
T41.2 Other and unspecified general anaesthetics	0.142	0.858	0.000
T41.1 Intravenous anaesthetics	0.142	0.858	0.000
T41.0 Inhaled anaesthetics	0.142	0.858	0.000
T49.9 Topical agent, unspecified	0.142	0.858	0.000
T49.8 Other topical agents	0.142	0.858	0.000
T49.7 Dental drugs, topically applied	0.142	0.858	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.142	0.858	0.000
T49.5 Ophthalmological drugs and preparations	0.142	0.858	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.142	0.858	0.000
T49.3 Emollients, demulcents and protectants	0.142	0.858	0.000
T49.2 Local astringents and local detergents	0.142	0.858	0.000
T49.1 Antipruritics	0.142	0.858	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.142	0.858	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.141	0.858	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.141	0.859	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.140	0.859	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.140	0.859	0.000
T46.7 Peripheral vasodilators	0.140	0.859	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.140	0.859	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.140	0.859	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.140	0.860	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.138	0.861	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.138	0.862	0.000
F43.9 Reaction to severe stress, unspecified	0.138	0.862	0.000
F20 Schizophrenia	0.136	0.863	0.000
F17.1 Harmful use	0.137	0.863	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.136	0.863	0.000
T40.4 Other synthetic narcotics	0.132	0.868	0.000
T36.9 Systemic antibiotic, unspecified	0.132	0.868	0.000
T36.8 Other systemic antibiotics	0.132	0.868	0.000
T36.7 Antifungal antibiotics, systemically used	0.132	0.868	0.000
T36.6 Rifamycins	0.132	0.868	0.000
T36.5 Aminoglycosides	0.132	0.868	0.000
T36.4 Tetracyclines	0.132	0.868	0.000
T36.3 Macrolides	0.132	0.868	0.000
T36.2 Chloramphenicol group	0.132	0.868	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.132	0.868	0.000
T46.1 Calcium-channel blockers	0.131	0.868	0.000
F13.9 Unspecified mental and behavioural disorder	0.128	0.871	0.000
F13.8 Other mental and behavioural disorders	0.128	0.871	0.000
F13.7 Residual and late-onset psychotic disorder	0.128	0.871	0.000
F13.6 Amnesic syndrome	0.128	0.871	0.000
F13.5 Psychotic disorder	0.128	0.871	0.000
F13.4 Withdrawal state with delirium	0.128	0.871	0.000
F13.3 Withdrawal state	0.128	0.871	0.000
F13.1 Harmful use	0.128	0.871	0.000
F13.0 Acute intoxication	0.128	0.871	0.000
F44.4 Dissociative motor disorders	0.128	0.871	0.000
F40.1 Social phobias	0.128	0.872	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.127	0.873	0.000
T40.8 Lysergide [LSD]	0.127	0.873	0.000
T40.7 Cannabis (derivatives)	0.127	0.873	0.000
T40.5 Cocaine	0.127	0.873	0.000
T40.3 Methadone	0.127	0.873	0.000
T40.1 Heroin	0.127	0.873	0.000
T40.0 Opium	0.127	0.873	0.000
F44.8 Other dissociative [conversion] disorders	0.125	0.875	0.000
F44.7 Mixed dissociative [conversion] disorders	0.125	0.875	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.125	0.875	0.000
F44.3 Trance and possession disorders	0.125	0.875	0.000
F44.2 Dissociative stupor	0.125	0.875	0.000
F44.1 Dissociative fugue	0.125	0.875	0.000
F44.0 Dissociative amnesia	0.125	0.875	0.000
F41 Other anxiety disorders	0.125	0.875	0.000
F44.5 Dissociative convulsions	0.123	0.877	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.120	0.880	0.000
T36.0 Penicillins	0.118	0.882	0.000
F14.9 Unspecified mental and behavioural disorder	0.115	0.884	0.000
F14.8 Other mental and behavioural disorders	0.115	0.884	0.000
F14.7 Residual and late-onset psychotic disorder	0.115	0.884	0.000
F14.6 Amnesic syndrome	0.115	0.884	0.000
F14.5 Psychotic disorder	0.115	0.884	0.000
F14.4 Withdrawal state with delirium	0.115	0.884	0.000
F14.3 Withdrawal state	0.115	0.884	0.000
F14.2 Dependence syndrome	0.115	0.884	0.000
F14.1 Harmful use	0.115	0.884	0.000
F14.0 Acute intoxication	0.115	0.884	0.000
F16.9 Unspecified mental and behavioural disorder	0.115	0.884	0.000
F16.8 Other mental and behavioural disorders	0.115	0.884	0.000
F16.7 Residual and late-onset psychotic disorder	0.115	0.884	0.000
F16.6 Amnesic syndrome	0.115	0.884	0.000
F16.5 Psychotic disorder	0.115	0.884	0.000
F16.4 Withdrawal state with delirium	0.115	0.884	0.000
F16.3 Withdrawal state	0.115	0.884	0.000
F16.2 Dependence syndrome	0.115	0.884	0.000
F16.1 Harmful use	0.115	0.884	0.000
F16.0 Acute intoxication	0.115	0.884	0.000
F18.9 Unspecified mental and behavioural disorder	0.115	0.884	0.000
F18.8 Other mental and behavioural disorders	0.115	0.884	0.000
F18.7 Residual and late-onset psychotic disorder	0.115	0.884	0.000
F18.6 Amnesic syndrome	0.115	0.884	0.000
F18.5 Psychotic disorder	0.115	0.884	0.000
F18.4 Withdrawal state with delirium	0.115	0.884	0.000
F18.3 Withdrawal state	0.115	0.884	0.000
F18.2 Dependence syndrome	0.115	0.884	0.000
F18.1 Harmful use	0.115	0.884	0.000
F18.0 Acute intoxication	0.115	0.884	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.115	0.885	0.000
T40.6 Other and unspecified narcotics	0.115	0.885	0.000
T45.2 Vitamins, not elsewhere classified	0.115	0.885	0.000
F17.9 Unspecified mental and behavioural disorder	0.112	0.887	0.000
F17.8 Other mental and behavioural disorders	0.112	0.887	0.000
F17.7 Residual and late-onset psychotic disorder	0.112	0.887	0.000
F17.6 Amnesic syndrome	0.112	0.887	0.000
F17.5 Psychotic disorder	0.112	0.887	0.000
F17.4 Withdrawal state with delirium	0.112	0.887	0.000
F17.3 Withdrawal state	0.112	0.887	0.000
F17.0 Acute intoxication	0.112	0.887	0.000
F40.0 Agoraphobia	0.112	0.888	0.000
T40.2 Other opioids	0.112	0.888	0.000
F15.9 Unspecified mental and behavioural disorder	0.112	0.888	0.000
F15.8 Other mental and behavioural disorders	0.112	0.888	0.000
F15.7 Residual and late-onset psychotic disorder	0.112	0.888	0.000
F15.6 Amnesic syndrome	0.112	0.888	0.000
F15.5 Psychotic disorder	0.112	0.888	0.000
F15.4 Withdrawal state with delirium	0.112	0.888	0.000
F15.3 Withdrawal state	0.112	0.888	0.000
F15.2 Dependence syndrome	0.112	0.888	0.000
F15.0 Acute intoxication	0.112	0.888	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.111	0.888	0.000
T45.8 Other primarily systemic and haematological agents	0.111	0.888	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.111	0.888	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations