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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10503951
log Bayes Factor = 6.24858
Chromosome 8   position 33,665,680  (GRCh37) Explore rs10503951 on Ensembl!
Variant rs10503951 is listed in the   GWAS Catalog   ⇪
Variant rs10503951 is part of Cluster X0197

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.999 0.001 0.000
C34 Malignant neoplasm of bronchus and lung
0.999 0.001 0.000
F30-F39 Mood [affective] disorders
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
F32 Depressive episode
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
J09-J18 Influenza and pneumonia
0.990 0.010 0.000
S00-S09 Injuries to the head
0.987 0.013 0.000
S00 Superficial injury of head
0.986 0.014 0.000
F32.9 Depressive episode, unspecified
0.985 0.015 0.000
S00.8 Superficial injury of other parts of head
0.984 0.016 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
C34.9 Bronchus or lung, unspecified
0.978 0.022 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.978 0.022 0.000
C34.3 Lower lobe, bronchus or lung
0.971 0.029 0.000
C34.1 Upper lobe, bronchus or lung
0.967 0.033 0.000
W00-W19 Falls
0.967 0.033 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.965 0.035 0.000
M80-M85 Disorders of bone density and structure
0.965 0.035 0.000
D00-D09 In situ neoplasms
0.964 0.036 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.959 0.041 0.000
M84 Disorders of continuity of bone
0.958 0.042 0.000
C51-C58 Malignant neoplasms of female genital organs
0.957 0.043 0.000
J18 Pneumonia, organism unspecified
0.957 0.043 0.000
T66-T78 Other and unspecified effects of external causes
0.953 0.047 0.000
J40-J47 Chronic lower respiratory diseases
0.951 0.049 0.000
F33 Recurrent depressive disorder
0.948 0.052 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.945 0.055 0.000
J44 Other chronic obstructive pulmonary disease
0.944 0.056 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
C50-C50 Malignant neoplasm of breast
0.941 0.058 0.000
J90-J94 Other diseases of pleura
0.940 0.060 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.940 0.060 0.000
M65-M68 Disorders of synovium and tendon
0.934 0.066 0.000
S40-S49 Injuries to the shoulder and upper arm
0.932 0.068 0.000
F10.3 Withdrawal state
0.929 0.071 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.927 0.073 0.000
T78 Adverse effects, not elsewhere classified
0.926 0.074 0.000
M65 Synovitis and tenosynovitis
0.919 0.081 0.000
C79 Secondary malignant neoplasm of other sites
0.916 0.084 0.000
M70-M79 Other soft tissue disorders
0.913 0.087 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.908 0.092 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.907 0.093 0.000
J11 Influenza, virus not identified
0.905 0.095 0.000
V20-V29 Motorcycle rider injured in transport accident
0.903 0.097 0.000
J93 Pneumothorax
0.903 0.097 0.000
C50 Malignant neoplasm of breast
0.900 0.100 0.000
F10.0 Acute intoxication
0.895 0.105 0.000
D06 Carcinoma in situ of cervix uteri
0.892 0.108 0.000
M79.8 Other specified soft tissue disorders
0.889 0.111 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.887 0.113 0.000
W19 Unspecified fall
0.884 0.116 0.000
F80-F89 Disorders of psychological development
0.883 0.117 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.878 0.122 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.878 0.122 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.877 0.123 0.000
D03 Melanoma in situ
0.872 0.128 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.871 0.129 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.870 0.130 0.000
J18.1 Lobar pneumonia, unspecified
0.870 0.130 0.000
C50.9 Breast, unspecified
0.866 0.134 0.000
C53 Malignant neoplasm of cervix uteri
0.865 0.135 0.000
T78.2 Anaphylactic shock, unspecified
0.865 0.135 0.000
M60-M63 Disorders of muscles
0.863 0.137 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.861 0.139 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.861 0.139 0.000
C78.0 Secondary malignant neoplasm of lung
0.860 0.140 0.000
T00-T07 Injuries involving multiple body regions
0.857 0.143 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.856 0.144 0.000
F33.9 Recurrent depressive disorder, unspecified
0.855 0.145 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.855 0.145 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.854 0.146 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.854 0.146 0.000
M79.7 Fibromyalgia
0.853 0.147 0.000
F10.2 Dependence syndrome
0.853 0.147 0.000
M79.0 Rheumatism, unspecified
0.851 0.149 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.850 0.150 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.849 0.151 0.000
J60-J70 Lung diseases due to external agents
0.847 0.153 0.000
Y40 Systemic antibiotics
0.844 0.156 0.000
W08 Fall involving other furniture
0.843 0.157 0.000
J17 Pneumonia in diseases classified elsewhere
0.843 0.157 0.000
M86-M90 Other osteopathies
0.842 0.158 0.000
J93.9 Pneumothorax, unspecified
0.840 0.160 0.000
D06.9 Cervix, unspecified
0.840 0.160 0.000
S01 Open wound of head
0.839 0.161 0.000
J18.9 Pneumonia, unspecified
0.838 0.162 0.000
W50-W64 Exposure to animate mechanical forces
0.837 0.163 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.837 0.163 0.000
Y43 Primarily systemic agents
0.834 0.166 0.000
Y57 Other and unspecified drugs and medicaments
0.834 0.166 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.830 0.170 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.829 0.171 0.000
C50.3 Lower-inner quadrant of breast
0.829 0.171 0.000
S42 Fracture of shoulder and upper arm
0.828 0.172 0.000
J42 Unspecified chronic bronchitis
0.827 0.173 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.826 0.174 0.000
M84.0 Malunion of fracture
0.825 0.175 0.000
M65.1 Other infective (teno)synovitis
0.825 0.175 0.000
T20 Burn and corrosion of head and neck
0.823 0.177 0.000
M79.79 Fibromyalgia (Site unspecified)
0.823 0.177 0.000
J91 Pleural effusion in conditions classified elsewhere
0.821 0.179 0.000
C51 Malignant neoplasm of vulva
0.816 0.184 0.000
M65.8 Other synovitis and tenosynovitis
0.815 0.185 0.000
W19.9 Unspecified place
0.813 0.187 0.000
F80 Specific developmental disorders of speech and language
0.813 0.187 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.813 0.187 0.000
S43.0 Dislocation of shoulder joint
0.813 0.187 0.000
W05 Fall involving wheelchair
0.812 0.188 0.000
S00.1 Contusion of eyelid and periocular area
0.812 0.188 0.000
Y44 Agents primarily affecting blood constituents
0.811 0.189 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.810 0.190 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.809 0.191 0.000
M84.4 Pathological fracture, not elsewhere classified
0.808 0.192 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.808 0.192 0.000
C80 Malignant neoplasm without specification of site
0.808 0.192 0.000
S00.0 Superficial injury of scalp
0.807 0.193 0.000
W06 Fall involving bed
0.801 0.199 0.000
C53.9 Cervix uteri, unspecified
0.799 0.201 0.000
D03.5 Melanoma in situ of trunk
0.796 0.204 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.796 0.204 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.795 0.205 0.000
T31 Burns classified according to extent of body surface involved
0.793 0.207 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.790 0.210 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.789 0.211 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.786 0.214 0.000
F32.8 Other depressive episodes
0.785 0.215 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.785 0.215 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.781 0.218 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.781 0.219 0.000
S00.5 Superficial injury of lip and oral cavity
0.780 0.220 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.779 0.221 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.779 0.221 0.000
J41 Simple and mucopurulent chronic bronchitis
0.776 0.224 0.000
V01-V09 Pedestrian injured in transport accident
0.775 0.224 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.775 0.225 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.773 0.227 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.773 0.227 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.772 0.228 0.000
V23.4 Driver injured in traffic accident
0.771 0.229 0.000
T25 Burn and corrosion of ankle and foot
0.771 0.229 0.000
Y43.3 Other antineoplastic drugs
0.771 0.229 0.000
C50.5 Lower-outer quadrant of breast
0.769 0.231 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.769 0.231 0.000
C78.2 Secondary malignant neoplasm of pleura
0.767 0.233 0.000
C50.0 Nipple and areola
0.766 0.234 0.000
X20-X29 Contact with venomous animals and plants
0.765 0.235 0.000
T00 Superficial injuries involving multiple body regions
0.764 0.236 0.000
S32 Fracture of lumbar spine and pelvis
0.764 0.236 0.000
J69 Pneumonitis due to solids and liquids
0.764 0.236 0.000
F80.1 Expressive language disorder
0.763 0.237 0.000
M40-M43 Deforming dorsopathies
0.763 0.237 0.000
Chapter VI Diseases of the nervous system
0.763 0.237 0.000
Y40.0 Penicillins
0.762 0.238 0.000
S00.7 Multiple superficial injuries of head
0.761 0.239 0.000
J93.0 Spontaneous tension pneumothorax
0.761 0.239 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.761 0.239 0.000
W14 Fall from tree
0.761 0.239 0.000
C78.7 Secondary malignant neoplasm of liver
0.760 0.240 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.759 0.241 0.000
J14 Pneumonia due to Haemophilus influenzae
0.757 0.242 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.757 0.243 0.000
W13 Fall from, out of or through building or structure
0.757 0.243 0.000
M00-M03 Infectious arthropathies
0.756 0.243 0.000
J10 Influenza due to identified influenza virus
0.755 0.245 0.000
V98-V99 Other and unspecified transport accidents
0.754 0.246 0.000
F60-F69 Disorders of adult personality and behaviour
0.753 0.247 0.000
Y48 Anaesthetics and therapeutic gases
0.752 0.248 0.000
V70-V79 Bus occupant injured in transport accident
0.751 0.249 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.751 0.249 0.000
F10.5 Psychotic disorder
0.751 0.249 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.749 0.251 0.000
J18.8 Other pneumonia, organism unspecified
0.748 0.252 0.000
D04 Carcinoma in situ of skin
0.747 0.253 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.747 0.253 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.746 0.254 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.746 0.254 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.743 0.257 0.000
Q21 Congenital malformations of cardiac septa
0.742 0.258 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.742 0.258 0.000
T23 Burn and corrosion of wrist and hand
0.742 0.258 0.000
S42.2 Fracture of upper end of humerus
0.741 0.259 0.000
J18.0 Bronchopneumonia, unspecified
0.741 0.259 0.000
M82 Osteoporosis in diseases classified elsewhere
0.741 0.259 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.739 0.261 0.000
C32 Malignant neoplasm of larynx
0.739 0.261 0.000
M62 Other disorders of muscle
0.738 0.262 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.737 0.263 0.000
T20.2 Burn of second degree of head and neck
0.736 0.264 0.000
F32.1 Moderate depressive episode
0.736 0.264 0.000
Q60-Q64 Congenital malformations of the urinary system
0.735 0.265 0.000
W17 Other fall from one level to another
0.734 0.266 0.000
M89 Other disorders of bone
0.733 0.267 0.000
T31.0 Burns involving less than 10% of body surface
0.732 0.268 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.732 0.268 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.731 0.269 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.730 0.270 0.000
T51 Toxic effect of alcohol
0.730 0.270 0.000
M84.03 Malunion of fracture (Forearm)
0.730 0.270 0.000
S00.3 Superficial injury of nose
0.729 0.271 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.729 0.271 0.000
M91-M94 Chondropathies
0.727 0.272 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.727 0.273 0.000
W19.4 Street and highway
0.726 0.274 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.726 0.274 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.725 0.275 0.000
S01.8 Open wound of other parts of head
0.724 0.276 0.000
W08.0 Home
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.722 0.278 0.000
F11 Mental and behavioural disorders due to use of opioids
0.721 0.279 0.000
J43 Emphysema
0.718 0.281 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.716 0.283 0.000
C31 Malignant neoplasm of accessory sinuses
0.716 0.283 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.716 0.283 0.000
C37 Malignant neoplasm of thymus
0.716 0.283 0.000
C33 Malignant neoplasm of trachea
0.716 0.283 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.716 0.284 0.000
Q50-Q56 Congenital malformations of genital organs
0.716 0.284 0.000
C34.8 Overlapping lesion of bronchus and lung
0.716 0.284 0.000
F38 Other mood [affective] disorders
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
C51.9 Vulva, unspecified
0.715 0.285 0.000
C56 Malignant neoplasm of ovary
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.286 0.000
S01.1 Open wound of eyelid and periocular area
0.711 0.288 0.000
V10-V19 Pedal cyclist injured in transport accident
0.711 0.289 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.711 0.289 0.000
S32.5 Fracture of pubis
0.710 0.290 0.000
F10.4 Withdrawal state with delirium
0.710 0.290 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.709 0.290 0.000
J12 Viral pneumonia, not elsewhere classified
0.709 0.290 0.000
J09 Influenza due to certain identified influenza virus
0.709 0.290 0.000
S08 Traumatic amputation of part of head
0.707 0.292 0.000
S07 Crushing injury of head
0.707 0.292 0.000
S04 Injury of cranial nerves
0.707 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.707 0.292 0.000
S00.4 Superficial injury of ear
0.707 0.293 0.000
F34 Persistent mood [affective] disorders
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
J69.0 Pneumonitis due to food and vomit
0.705 0.295 0.000
Y44.2 Anticoagulants
0.705 0.295 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.705 0.295 0.000
W18 Other fall on same level
0.704 0.296 0.000
T56 Toxic effect of metals
0.704 0.296 0.000
F32.0 Mild depressive episode
0.704 0.296 0.000
C52 Malignant neoplasm of vagina
0.704 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
W15 Fall from cliff
0.703 0.296 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.703 0.297 0.000
F99-F99 Unspecified mental disorder
0.702 0.298 0.000
M60 Myositis
0.701 0.299 0.000
J93.1 Other spontaneous pneumothorax
0.701 0.299 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.701 0.299 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.701 0.299 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.701 0.299 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.701 0.299 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.701 0.299 0.000
J11.0 Influenza with pneumonia, virus not identified
0.699 0.301 0.000
J92 Pleural plaque
0.699 0.301 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.699 0.301 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.698 0.302 0.000
F30 Manic episode
0.696 0.304 0.000
T70 Effects of air pressure and water pressure
0.695 0.305 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.695 0.305 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.693 0.307 0.000
W12 Fall on and from scaffolding
0.693 0.307 0.000
W11 Fall on and from ladder
0.693 0.307 0.000
W09 Fall involving playground equipment
0.693 0.307 0.000
W04 Fall while being carried or supported by other persons
0.693 0.307 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.693 0.307 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.693 0.307 0.000
W00 Fall on same level involving ice and snow
0.693 0.307 0.000
F10.9 Unspecified mental and behavioural disorder
0.692 0.308 0.000
F10.8 Other mental and behavioural disorders
0.692 0.308 0.000
F10.7 Residual and late-onset psychotic disorder
0.692 0.308 0.000
F10.6 Amnesic syndrome
0.692 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.692 0.308 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.692 0.308 0.000
Y54.5 Other diuretics
0.692 0.308 0.000
M83 Adult osteomalacia
0.692 0.308 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.692 0.308 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y57.9 Drug or medicament, unspecified
0.689 0.311 0.000
M79.2 Neuralgia and neuritis, unspecified
0.689 0.311 0.000
Y59 Other and unspecified vaccines and biological substances
0.688 0.312 0.000
Y58 Bacterial vaccines
0.688 0.312 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.688 0.312 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.688 0.312 0.000
M84.9 Disorder of continuity of bone, unspecified
0.687 0.313 0.000
M84.8 Other disorders of continuity of bone
0.687 0.313 0.000
M84.3 Stress fracture, not elsewhere classified
0.687 0.313 0.000
M84.2 Delayed union of fracture
0.687 0.313 0.000
W51 Striking against or bumped into by another person
0.687 0.313 0.000
C58 Malignant neoplasm of placenta
0.686 0.314 0.000
J18.2 Hypostatic pneumonia, unspecified
0.686 0.314 0.000
C09 Malignant neoplasm of tonsil
0.686 0.314 0.000
Y00-Y09 Assault
0.685 0.315 0.000
W19.2 School, other institution and public administrative area
0.685 0.315 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.684 0.315 0.000
Y54.3 Benzothiadiazine derivatives
0.684 0.316 0.000
T75 Effects of other external causes
0.683 0.317 0.000
T74 Maltreatment syndromes
0.683 0.317 0.000
T73 Effects of other deprivation
0.683 0.317 0.000
T69 Other effects of reduced temperature
0.683 0.317 0.000
T67 Effects of heat and light
0.683 0.317 0.000
T71 Asphyxiation
0.683 0.317 0.000
T66 Unspecified effects of radiation
0.683 0.317 0.000
T78.3 Angioneurotic oedema
0.683 0.317 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.683 0.317 0.000
Q24 Other congenital malformations of heart
0.682 0.317 0.000
W05.9 Unspecified place
0.681 0.319 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.681 0.319 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.681 0.319 0.000
S42.20 Fracture of upper end of humerus (closed)
0.680 0.320 0.000
F33.8 Other recurrent depressive disorders
0.680 0.320 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.680 0.320 0.000
S42.4 Fracture of lower end of humerus
0.679 0.321 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.679 0.321 0.000
F39 Unspecified mood [affective] disorder
0.679 0.321 0.000
T21 Burn and corrosion of trunk
0.678 0.322 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
Q21.1 Atrial septal defect
0.676 0.324 0.000
T78.4 Allergy, unspecified
0.675 0.325 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.674 0.326 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.674 0.326 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.674 0.326 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.674 0.326 0.000
S32.50 Fracture of pubis (closed)
0.672 0.328 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.670 0.330 0.000
C01 Malignant neoplasm of base of tongue
0.670 0.330 0.000
M76 Enthesopathies of lower limb, excluding foot
0.669 0.331 0.000
S48 Traumatic amputation of shoulder and upper arm
0.668 0.332 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.668 0.332 0.000
S44 Injury of nerves at shoulder and upper arm level
0.668 0.332 0.000
S47 Crushing injury of shoulder and upper arm
0.668 0.332 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.668 0.332 0.000
C79.6 Secondary malignant neoplasm of ovary
0.668 0.332 0.000
S31 Open wound of abdomen, lower back and pelvis
0.667 0.333 0.000
T58 Toxic effect of carbon monoxide
0.666 0.334 0.000
W08.9 Unspecified place
0.666 0.334 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.664 0.335 0.000
Y57.5 X-ray contrast media
0.664 0.336 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.664 0.336 0.000
Q66 Congenital deformities of feet
0.664 0.336 0.000
T78.9 Adverse effect, unspecified
0.664 0.336 0.000
T78.8 Other adverse effects, not elsewhere classified
0.664 0.336 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.663 0.337 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.662 0.337 0.000
F02 Dementia in other diseases classified elsewhere
0.662 0.338 0.000
W06.0 Home
0.661 0.339 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.661 0.339 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.339 0.000
M65.2 Calcific tendinitis
0.659 0.341 0.000
M65.0 Abscess of tendon sheath
0.659 0.341 0.000
C34.2 Middle lobe, bronchus or lung
0.659 0.341 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.659 0.341 0.000
M86 Osteomyelitis
0.658 0.342 0.000
J60 Coalworker's pneumoconiosis
0.658 0.342 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.658 0.342 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.657 0.343 0.000
W55 Bitten or struck by other mammals
0.656 0.344 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.656 0.344 0.000
G30-G32 Other degenerative diseases of the nervous system
0.655 0.345 0.000
C57.0 Fallopian tube
0.655 0.345 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.655 0.345 0.000
G35 Multiple sclerosis
0.654 0.346 0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)
0.653 0.347 0.000
Y54.4 Loop [high-ceiling] diuretics
0.653 0.347 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.652 0.348 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.651 0.349 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.651 0.349 0.000
M79.3 Panniculitis, unspecified
0.651 0.349 0.000
J41.0 Simple chronic bronchitis
0.651 0.349 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.650 0.350 0.000
J11.8 Influenza with other manifestations, virus not identified
0.649 0.351 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.649 0.351 0.000
J93.8 Other pneumothorax
0.649 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.649 0.351 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.647 0.353 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.647 0.353 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.647 0.353 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.647 0.353 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.647 0.353 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.647 0.353 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.647 0.353 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.647 0.353 0.000
M89.8 Other specified disorders of bone
0.647 0.353 0.000
T25.2 Burn of second degree of ankle and foot
0.647 0.353 0.000
C50.6 Axillary tail of breast
0.645 0.355 0.000
S01.7 Multiple open wounds of head
0.644 0.356 0.000
M71 Other bursopathies
0.643 0.356 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.643 0.357 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.642 0.358 0.000
M81 Osteoporosis without pathological fracture
0.642 0.358 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.641 0.359 0.000
C10 Malignant neoplasm of oropharynx
0.641 0.359 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.641 0.359 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.640 0.360 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.640 0.360 0.000
Y43.4 Immunosuppressive agents
0.640 0.360 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.640 0.360 0.000
Q00-Q07 Congenital malformations of the nervous system
0.639 0.360 0.000
D06.7 Other parts of cervix
0.639 0.360 0.000
D06.1 Exocervix
0.639 0.360 0.000
D06.0 Endocervix
0.639 0.360 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.639 0.361 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.639 0.361 0.000
Y40.3 Macrolides
0.639 0.361 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.638 0.362 0.000
Y47.1 Benzodiazepines
0.638 0.362 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.637 0.362 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.636 0.364 0.000
S41 Open wound of shoulder and upper arm
0.636 0.364 0.000
T00.8 Superficial injuries involving other combinations of body regions
0.635 0.365 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.634 0.366 0.000
W19.8 Other specified place
0.634 0.366 0.000
W19.5 Trade and service area
0.634 0.366 0.000
W19.0 Home
0.634 0.366 0.000
W19.7 Farm
0.634 0.366 0.000
W19.6 Industrial and construction area
0.634 0.366 0.000
M40 Kyphosis and lordosis
0.633 0.367 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.633 0.367 0.000
Q61 Cystic kidney disease
0.633 0.367 0.000
F89 Unspecified disorder of psychological development
0.633 0.367 0.000
F88 Other disorders of psychological development
0.633 0.367 0.000
F83 Mixed specific developmental disorders
0.633 0.367 0.000
F82 Specific developmental disorder of motor function
0.633 0.367 0.000
C50.8 Overlapping lesion of breast
0.632 0.368 0.000
M90 Osteopathies in diseases classified elsewhere
0.632 0.368 0.000
C77.0 Lymph nodes of head, face and neck
0.632 0.368 0.000
X50-X57 Overexertion, travel and privation
0.631 0.369 0.000
X60-X84 Intentional self-harm
0.630 0.370 0.000
T68 Hypothermia
0.630 0.370 0.000
F13.2 Dependence syndrome
0.630 0.370 0.000
M85 Other disorders of bone density and structure
0.630 0.370 0.000
J94 Other pleural conditions
0.630 0.370 0.000
T32 Corrosions classified according to extent of body surface involved
0.630 0.370 0.000
T30 Burn and corrosion, body region unspecified
0.630 0.370 0.000
T29 Burns and corrosions of multiple body regions
0.630 0.370 0.000
M65.3 Trigger finger
0.630 0.370 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.630 0.370 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.629 0.370 0.000
F00 Dementia in Alzheimer's disease
0.629 0.371 0.000
C80.9 Malignant neoplasm, unspecified
0.629 0.371 0.000
D09 Carcinoma in situ of other and unspecified sites
0.629 0.371 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.629 0.371 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.629 0.371 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.629 0.371 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.629 0.371 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.629 0.371 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.629 0.371 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.629 0.371 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.629 0.371 0.000
Y57.6 Other diagnostic agents
0.629 0.371 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.628 0.372 0.000
T51.9 Alcohol, unspecified
0.627 0.373 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.626 0.374 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
D03.9 Melanoma in situ, unspecified
0.625 0.375 0.000
D03.8 Melanoma in situ of other sites
0.625 0.375 0.000
D03.4 Melanoma in situ of scalp and neck
0.625 0.375 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.625 0.375 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.625 0.375 0.000
D03.0 Melanoma in situ of lip
0.625 0.375 0.000
D04.5 Skin of trunk
0.625 0.375 0.000
S01.3 Open wound of ear
0.624 0.376 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.624 0.376 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.624 0.376 0.000
S37 Injury of urinary and pelvic organs
0.624 0.376 0.000
S36 Injury of intra-abdominal organs
0.624 0.376 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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