TreeWAS – Variant ID: rs10515552

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
M80-M85 Disorders of bone density and structure	0.996	0.004
M81 Osteoporosis without pathological fracture	0.994	0.006
M81.9 Osteoporosis, unspecified	0.989	0.011
S60-S69 Injuries to the wrist and hand	0.988	0.012
O94-O99 Other obstetric conditions, not elsewhere classified	0.988	0.012
S50-S59 Injuries to the elbow and forearm	0.983	0.017
O60-O75 Complications of labour and delivery	0.981	0.019
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.979	0.021
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.976	0.024
S52 Fracture of forearm	0.966	0.034
Z37 Outcome of delivery	0.966	0.034
Z37.0 Single live birth	0.963	0.037
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.961	0.039
M81.99 Osteoporosis, unspecified (Site unspecified)	0.958	0.042
Chapter XXI Factors influencing health status and contact with health services	0.957	0.043
S66 Injury of muscle and tendon at wrist and hand level	0.957	0.043
S52.5 Fracture of lower end of radius	0.954	0.046
O46 Antepartum haemorrhage, not elsewhere classified	0.954	0.046
M81.98 Osteoporosis, unspecified (Other)	0.951	0.049
O72 Postpartum haemorrhage	0.949	0.051
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.947	0.053
O20-O29 Other maternal disorders predominantly related to pregnancy	0.945	0.055
S52.50 Fracture of lower end of radius (closed)	0.943	0.057
Z37.2 Twins, both liveborn	0.939	0.061
T36-T50 Poisoning by drugs, medicaments and biological substances	0.937	0.063
O16 Unspecified maternal hypertension	0.931	0.069
Chapter X Diseases of the respiratory system	0.931	0.069
S00-S09 Injuries to the head	0.928	0.072
J40-J47 Chronic lower respiratory diseases	0.925	0.075
J44 Other chronic obstructive pulmonary disease	0.924	0.076
O30 Multiple gestation	0.918	0.082
O34 Maternal care for known or suspected abnormality of pelvic organs	0.916	0.084
T66-T78 Other and unspecified effects of external causes	0.914	0.086
Z36 Antenatal screening	0.913	0.087
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.913	0.087
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.913	0.087
O72.1 Other immediate postpartum haemorrhage	0.911	0.089
J44.9 Chronic obstructive pulmonary disease, unspecified	0.910	0.090
O46.9 Antepartum haemorrhage, unspecified	0.908	0.092
S10-S19 Injuries to the neck	0.904	0.096
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.883	0.117
O26 Maternal care for other conditions predominantly related to pregnancy	0.883	0.117
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.876	0.124
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.876	0.124
M20-M25 Other joint disorders	0.872	0.128
M81.4 Drug-induced osteoporosis	0.867	0.133
S60 Superficial injury of wrist and hand	0.866	0.134
O80-O84 Delivery	0.866	0.134
J80-J84 Other respiratory diseases principally affecting the interstitium	0.863	0.137
O30.0 Twin pregnancy	0.860	0.140
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.857	0.143
T78 Adverse effects, not elsewhere classified	0.853	0.147
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.852	0.148
O85-O92 Complications predominantly related to the puerperium	0.839	0.161
J84 Other interstitial pulmonary diseases	0.837	0.163
O34.2 Maternal care due to uterine scar from previous surgery	0.836	0.164
S90-S99 Injuries to the ankle and foot	0.833	0.167
Z36.8 Other antenatal screening	0.833	0.167
S01 Open wound of head	0.828	0.172
J40 Bronchitis, not specified as acute or chronic	0.828	0.172
T79-T79 Certain early complications of trauma	0.826	0.174
M86-M90 Other osteopathies	0.818	0.182
T90 Sequelae of injuries of head	0.814	0.186
O43 Placental disorders	0.813	0.186
O72.0 Third-stage haemorrhage	0.810	0.190
M84 Disorders of continuity of bone	0.808	0.191
O47 False labour	0.806	0.194
S56 Injury of muscle and tendon at forearm level	0.806	0.194
O73 Retained placenta and membranes, without haemorrhage	0.806	0.194
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.803	0.197
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.803	0.197
S05 Injury of eye and orbit	0.802	0.198
O26.8 Other specified pregnancy-related conditions	0.801	0.199
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.801	0.199
O14.9 Preeclampsia, unspecified	0.800	0.200
O75 Other complications of labour and delivery, not elsewhere classified	0.798	0.202
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.796	0.204
O66 Other obstructed labour	0.793	0.207
S62 Fracture at wrist and hand level	0.793	0.207
Chapter XX External causes of morbidity and mortality	0.789	0.211
M40-M43 Deforming dorsopathies	0.785	0.215
Q20-Q28 Congenital malformations of the circulatory system	0.784	0.216
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.783	0.217
J84.1 Other interstitial pulmonary diseases with fibrosis	0.783	0.217
O63 Long labour	0.781	0.219
T20-T25 Burns and corrosions of external body surface, specified by site	0.778	0.222
S52.1 Fracture of upper end of radius	0.774	0.226
Chapter XXII Codes for special purposes	0.772	0.228
O20 Haemorrhage in early pregnancy	0.772	0.228
M85 Other disorders of bone density and structure	0.771	0.229
M80 Osteoporosis with pathological fracture	0.770	0.230
O46.8 Other antepartum haemorrhage	0.768	0.232
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.768	0.232
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.768	0.232
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.767	0.233
S20-S29 Injuries to the thorax	0.766	0.234
M81.90 Osteoporosis, unspecified (Multiple sites)	0.766	0.234
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.766	0.234
O35 Maternal care for known or suspected foetal abnormality and damage	0.765	0.235
Z36.2 Other antenatal screening based on amniocentesis	0.765	0.235
S02 Fracture of skull and facial bones	0.763	0.237
M91-M94 Chondropathies	0.762	0.238
S52.51 Fracture of lower end of radius (open)	0.761	0.239
O41 Other disorders of amniotic fluid and membranes	0.759	0.241
M82 Osteoporosis in diseases classified elsewhere	0.758	0.242
T93 Sequelae of injuries of lower limb	0.757	0.243
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.757	0.243
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.757	0.243
Q60-Q64 Congenital malformations of the urinary system	0.757	0.243
S01.8 Open wound of other parts of head	0.756	0.244
Z35 Supervision of high-risk pregnancy	0.756	0.244
M21 Other acquired deformities of limbs	0.754	0.246
M81.2 Osteoporosis of disuse	0.753	0.247
S14 Injury of nerves and spinal cord at neck level	0.751	0.249
T78.4 Allergy, unspecified	0.750	0.250
M23 Internal derangement of knee	0.749	0.251
O82 Single delivery by Caesarean section	0.749	0.251
S64 Injury of nerves at wrist and hand level	0.748	0.252
T15-T19 Effects of foreign body entering through natural orifice	0.748	0.252
M60-M63 Disorders of muscles	0.746	0.254
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.745	0.255
S12 Fracture of neck	0.744	0.256
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.742	0.258
S67 Crushing injury of wrist and hand	0.742	0.258
O48 Prolonged pregnancy	0.742	0.258
S50 Superficial injury of forearm	0.741	0.259
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.739	0.261
T36 Poisoning by systemic antibiotics	0.737	0.263
S01.1 Open wound of eyelid and periocular area	0.737	0.263
T00-T07 Injuries involving multiple body regions	0.736	0.264
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.736	0.264
M81.40 Drug-induced osteoporosis (Multiple sites)	0.735	0.264
Q38-Q45 Other congenital malformations of the digestive system	0.735	0.265
S69 Other and unspecified injuries of wrist and hand	0.735	0.265
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.735	0.265
J95-J99 Other diseases of the respiratory system	0.732	0.268
T78.2 Anaphylactic shock, unspecified	0.731	0.269
S91 Open wound of ankle and foot	0.728	0.272
M20 Acquired deformities of fingers and toes	0.728	0.272
S68 Traumatic amputation of wrist and hand	0.727	0.273
O26.2 Pregnancy care of habitual aborter	0.724	0.276
O34.7 Maternal care for abnormality of vulva and perineum	0.724	0.276
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.723	0.276
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.723	0.277
S60.9 Superficial injury of wrist and hand, unspecified	0.722	0.278
M20.1 Hallux valgus (acquired)	0.722	0.278
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.721	0.279
O44 Placenta praevia	0.721	0.279
S19 Other and unspecified injuries of neck	0.720	0.280
Chapter V Mental and behavioural disorders	0.719	0.281
S60.8 Other superficial injuries of wrist and hand	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
O45 Premature separation of placenta [abruptio placentae]	0.715	0.285
O33 Maternal care for known or suspected disproportion	0.715	0.285
O31 Complications specific to multiple gestation	0.715	0.285
Q80-Q89 Other congenital malformations	0.715	0.285
M83 Adult osteomalacia	0.714	0.286
M81.8 Other osteoporosis	0.713	0.287
M81.6 Localised osteoporosis [Lequesne]	0.713	0.287
M81.5 Idiopathic osteoporosis	0.713	0.287
M81.3 Postsurgical malabsorption osteoporosis	0.713	0.287
M81.1 Postoophorectomy osteoporosis	0.713	0.287
M81.0 Postmenopausal osteoporosis	0.713	0.287
Q76 Congenital malformations of spine and bony thorax	0.711	0.289
O42 Premature rupture of membranes	0.711	0.289
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.710	0.290
M23.3 Other meniscus derangements	0.710	0.290
S52.6 Fracture of lower end of both ulna and radius	0.710	0.290
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.710	0.290
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.709	0.291
M81.96 Osteoporosis, unspecified (Lower leg)	0.709	0.291
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.709	0.291
M81.94 Osteoporosis, unspecified (Hand)	0.709	0.291
M81.93 Osteoporosis, unspecified (Forearm)	0.709	0.291
M81.92 Osteoporosis, unspecified (Upper arm)	0.709	0.291
M81.91 Osteoporosis, unspecified (Shoulder region)	0.709	0.291
S65 Injury of blood vessels at wrist and hand level	0.708	0.292
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.708	0.292
O97 Death from sequelae of direct obstetric causes	0.708	0.292
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.708	0.292
O95 Obstetric death of unspecified cause	0.708	0.292
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.708	0.292
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.706	0.294
O64 Obstructed labour due to malposition and malpresentation of foetus	0.705	0.295
Q00-Q07 Congenital malformations of the nervous system	0.705	0.295
S59 Other and unspecified injuries of forearm	0.705	0.295
S58 Traumatic amputation of forearm	0.705	0.295
S57 Crushing injury of forearm	0.705	0.295
S55 Injury of blood vessels at forearm level	0.705	0.295
S54 Injury of nerves at forearm level	0.705	0.295
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.705	0.295
T42.4 Benzodiazepines	0.704	0.296
O74 Complications of anaesthesia during labour and delivery	0.703	0.297
O71 Other obstetric trauma	0.703	0.297
O65 Obstructed labour due to maternal pelvic abnormality	0.703	0.297
O60 Preterm delivery	0.703	0.297
O21 Excessive vomiting in pregnancy	0.703	0.297
S01.4 Open wound of cheek and temporomandibular area	0.703	0.297
M00-M03 Infectious arthropathies	0.702	0.297
M70-M79 Other soft tissue disorders	0.702	0.298
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.702	0.298
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.702	0.298
J84.8 Other specified interstitial pulmonary diseases	0.702	0.298
T79 Certain early complications of trauma, not elsewhere classified	0.702	0.298
O15 Eclampsia	0.700	0.300
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.700	0.300
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.700	0.300
O40 Polyhydramnios	0.699	0.300
O47.0 False labour before 37 completed weeks of gestation	0.699	0.301
M81.49 Drug-induced osteoporosis (Site unspecified)	0.698	0.302
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.696	0.304
J84.9 Interstitial pulmonary disease, unspecified	0.694	0.305
T91 Sequelae of injuries of neck and trunk	0.694	0.306
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.694	0.306
S70-S79 Injuries to the hip and thigh	0.694	0.306
O61 Failed induction of labour	0.693	0.307
T90.2 Sequelae of fracture of skull and facial bones	0.693	0.307
S52.9 Fracture of forearm, part unspecified	0.692	0.308
S52.7 Multiple fractures of forearm	0.692	0.308
S52.4 Fracture of shafts of both ulna and radius	0.692	0.308
S52.3 Fracture of shaft of radius	0.692	0.308
S52.2 Fracture of shaft of ulna	0.692	0.308
Z37.9 Outcome of delivery unspecified	0.692	0.308
Z37.7 Other multiple births, all stillborn	0.692	0.308
Z37.6 Other multiple births, some liveborn	0.692	0.308
Z37.5 Other multiple births, all liveborn	0.692	0.308
Z37.4 Twins, both stillborn	0.692	0.308
Z37.3 Twins, one liveborn and one stillborn	0.692	0.308
Z37.1 Single stillbirth	0.692	0.308
O32 Maternal care for known or suspected malpresentation of foetus	0.690	0.310
Z38 Liveborn infants according to place of birth	0.689	0.311
O43.8 Other placental disorders	0.689	0.311
T94 Sequelae of injuries involving multiple and unspecified body regions	0.688	0.312
S02.4 Fracture of malar and maxillary bones	0.687	0.313
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.686	0.314
S66.8 Injury of other muscles and tendons at wrist and hand level	0.686	0.314
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.686	0.314
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.686	0.314
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.686	0.314
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.686	0.314
O68 Labour and delivery complicated by foetal stress [distress]	0.685	0.315
M84.1 Nonunion of fracture [pseudarthrosis]	0.684	0.316
O46.0 Antepartum haemorrhage with coagulation defect	0.684	0.316
O14.0 Moderate preeclampsia	0.684	0.316
O73.0 Retained placenta, without haemorrhage	0.680	0.320
O72.3 Postpartum coagulation defects	0.680	0.320
S06 Intracranial injury	0.680	0.320
M45-M49 Spondylopathies	0.679	0.321
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.679	0.321
Q35-Q37 Cleft lip and cleft palate	0.679	0.321
Q30-Q34 Congenital malformations of the respiratory system	0.679	0.321
Z36.9 Antenatal screening, unspecified	0.678	0.322
M41 Scoliosis	0.678	0.322
O29 Complications of anaesthesia during pregnancy	0.677	0.323
O28 Abnormal findings on antenatal screening of mother	0.677	0.323
O23 Infections of genito-urinary tract in pregnancy	0.677	0.323
O22 Venous complications in pregnancy	0.677	0.323
O25 Malnutrition in pregnancy	0.677	0.323
T98 Sequelae of other and unspecified effects of external causes	0.677	0.323
O20.0 Threatened abortion	0.673	0.327
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.672	0.328
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.672	0.328
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.672	0.328
T41 Poisoning by anaesthetics and therapeutic gases	0.672	0.328
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.672	0.328
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.672	0.328
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.672	0.328
O92 Other disorders of breast and lactation associated with childbirth	0.671	0.329
J44.8 Other specified chronic obstructive pulmonary disease	0.670	0.330
S61 Open wound of wrist and hand	0.668	0.332
X60-X84 Intentional self-harm	0.667	0.333
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.666	0.334
S08 Traumatic amputation of part of head	0.666	0.334
S07 Crushing injury of head	0.666	0.334
S04 Injury of cranial nerves	0.666	0.334
S03 Dislocation, sprain and strain of joints and ligaments of head	0.666	0.334
T90.9 Sequelae of unspecified injury of head	0.664	0.336
O81 Single delivery by forceps and vacuum extractor	0.664	0.336
J41 Simple and mucopurulent chronic bronchitis	0.663	0.337
M25 Other joint disorders, not elsewhere classified	0.663	0.337
Z35.5 Supervision of elderly primigravida	0.661	0.339
S05.8 Other injuries of eye and orbit	0.659	0.341
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.658	0.341
O30.9 Multiple gestation, unspecified	0.658	0.342
O30.8 Other multiple gestation	0.658	0.342
O30.2 Quadruplet pregnancy	0.658	0.342
O30.1 Triplet pregnancy	0.658	0.342
M89 Other disorders of bone	0.657	0.343
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.657	0.343
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.656	0.343
O34.8 Maternal care for other abnormalities of pelvic organs	0.656	0.343
O34.6 Maternal care for abnormality of vagina	0.656	0.343
O34.5 Maternal care for other abnormalities of gravid uterus	0.656	0.343
O34.4 Maternal care for other abnormalities of cervix	0.656	0.343
O34.3 Maternal care for cervical incompetence	0.656	0.343
O34.1 Maternal care for tumour of corpus uteri	0.656	0.343
O34.0 Maternal care for congenital malformation of uterus	0.656	0.343
T75 Effects of other external causes	0.656	0.344
T74 Maltreatment syndromes	0.656	0.344
T73 Effects of other deprivation	0.656	0.344
T70 Effects of air pressure and water pressure	0.656	0.344
T69 Other effects of reduced temperature	0.656	0.344
T67 Effects of heat and light	0.656	0.344
T71 Asphyxiation	0.656	0.344
T68 Hypothermia	0.656	0.344
T66 Unspecified effects of radiation	0.656	0.344
Z36.5 Antenatal screening for isoimmunisation	0.655	0.345
Z36.1 Antenatal screening for raised alphafetoprotein level	0.655	0.345
T95 Sequelae of burns, corrosions and frostbite	0.655	0.345
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.655	0.345
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.655	0.345
Z39 Postpartum care and examination	0.654	0.346
O62 Abnormalities of forces of labour	0.654	0.346
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.652	0.347
S10 Superficial injury of neck	0.652	0.348
S05.1 Contusion of eyeball and orbital tissues	0.652	0.348
O24 Diabetes mellitus in pregnancy	0.651	0.348
O75.0 Maternal distress during labour and delivery	0.650	0.350
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.650	0.350
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.649	0.351
O75.8 Other specified complications of labour and delivery	0.649	0.351
S17 Crushing injury of neck	0.648	0.351
S15 Injury of blood vessels at neck level	0.648	0.351
S11 Open wound of neck	0.648	0.351
S18 Traumatic amputation at neck level	0.648	0.351
S16 Injury of muscle and tendon at neck level	0.648	0.351
T46 Poisoning by agents primarily affecting the cardiovascular system	0.648	0.352
S52.8 Fracture of other parts of forearm	0.647	0.353
S62.7 Multiple fractures of fingers	0.645	0.355
W00-W19 Falls	0.645	0.355
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.643	0.357
S27 Injury of other and unspecified intrathoracic organs	0.642	0.358
S14.1 Other and unspecified injuries of cervical spinal cord	0.641	0.359
M87 Osteonecrosis	0.640	0.360
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.639	0.361
S01.5 Open wound of lip and oral cavity	0.639	0.361
T78.3 Angioneurotic oedema	0.638	0.362
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.637	0.363
S52.10 Fracture of upper end of radius (closed)	0.637	0.363
S62.8 Fracture of other and unspecified parts of wrist and hand	0.636	0.363
S50.8 Other superficial injuries of forearm	0.636	0.364
O87 Venous complications in the puerperium	0.635	0.365
Q61 Cystic kidney disease	0.634	0.366
T78.0 Anaphylactic shock due to adverse food reaction	0.633	0.366
O14.2 HELLP syndrome	0.633	0.367
O14.1 Severe preeclampsia	0.633	0.367
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.633	0.367
O26.5 Maternal hypotension syndrome	0.633	0.367
O26.4 Herpes gestationis	0.633	0.367
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.633	0.367
O26.1 Low weight gain in pregnancy	0.633	0.367
O26.0 Excessive weight gain in pregnancy	0.633	0.367
S02.40 Fracture of malar and maxillary bones (closed)	0.633	0.367
F30-F39 Mood [affective] disorders	0.632	0.368
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.632	0.368
S12.1 Fracture of second cervical vertebra	0.631	0.368
O26.9 Pregnancy-related condition, unspecified	0.631	0.369
O72.2 Delayed and secondary postpartum haemorrhage	0.631	0.369
O75.2 Pyrexia during labour, not elsewhere classified	0.630	0.370
Z32 Pregnancy examination and test	0.629	0.370
T90.4 Sequelae of injury of eye and orbit	0.629	0.370
T93.0 Sequelae of open wound of lower limb	0.629	0.371
M23.4 Loose body in knee	0.629	0.371
O63.0 Prolonged first stage (of labour)	0.629	0.371
O90 Complications of the puerperium, not elsewhere classified	0.628	0.372
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.628	0.372
O47.9 False labour, unspecified	0.628	0.372
M24 Other specific joint derangements	0.628	0.372
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.627	0.373
J95 Postprocedural respiratory disorders, not elsewhere classified	0.626	0.374
S62.0 Fracture of navicular [scaphoid] bone of hand	0.626	0.374
O86 Other puerperal infections	0.626	0.374
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.625	0.375
M33 Dermatopolymyositis	0.625	0.375
M32 Systemic lupus erythematosus	0.625	0.375
M30 Polyarteritis nodosa and related conditions	0.625	0.375
S92 Fracture of foot, except ankle	0.625	0.375
O82.9 Delivery by Caesarean section, unspecified	0.625	0.375
O80 Single spontaneous delivery	0.624	0.376
Q76.0 Spina bifida occulta	0.623	0.377
S51 Open wound of forearm	0.622	0.378
M81.48 Drug-induced osteoporosis (Other)	0.622	0.378
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.622	0.378
M81.46 Drug-induced osteoporosis (Lower leg)	0.622	0.378
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.622	0.378
M81.44 Drug-induced osteoporosis (Hand)	0.622	0.378
M81.43 Drug-induced osteoporosis (Forearm)	0.622	0.378
M81.42 Drug-induced osteoporosis (Upper arm)	0.622	0.378
M81.41 Drug-induced osteoporosis (Shoulder region)	0.622	0.378
O69 Labour and delivery complicated by umbilical cord complications	0.621	0.379
S60.7 Multiple superficial injuries of wrist and hand	0.621	0.379
S60.2 Contusion of other parts of wrist and hand	0.621	0.379
S60.1 Contusion of finger(s) with damage to nail	0.621	0.379
S60.0 Contusion of finger(s) without damage to nail	0.621	0.379
O84 Multiple delivery	0.621	0.379
O83 Other assisted single delivery	0.621	0.379
Q21 Congenital malformations of cardiac septa	0.619	0.381
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.619	0.381
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.619	0.381
D68 Other coagulation defects	0.619	0.381
J82 Pulmonary eosinophilia, not elsewhere classified	0.619	0.381
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.617	0.383
M21.3 Wrist or foot drop (acquired)	0.617	0.383
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.615	0.384
W50-W64 Exposure to animate mechanical forces	0.615	0.385
M80.0 Postmenopausal osteoporosis with pathological fracture	0.614	0.385
Z31 Procreative management	0.614	0.385
S09 Other and unspecified injuries of head	0.614	0.386
S64.0 Injury of ulnar nerve at wrist and hand level	0.613	0.386
M23.30 Other meniscus derangements (Multiple sites)	0.614	0.386
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.613	0.387
Q50-Q56 Congenital malformations of genital organs	0.613	0.387
Z30 Contraceptive management	0.613	0.387
M21.6 Other acquired deformities of ankle and foot	0.613	0.387
Q24 Other congenital malformations of heart	0.613	0.387
T78.9 Adverse effect, unspecified	0.612	0.388
T78.8 Other adverse effects, not elsewhere classified	0.612	0.388
S62.4 Multiple fractures of metacarpal bones	0.611	0.388
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.609	0.391
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.607	0.393
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.607	0.393
O36 Maternal care for other known or suspected foetal problems	0.606	0.394
S91.1 Open wound of toe(s) without damage to nail	0.606	0.394
T78.1 Other adverse food reactions, not elsewhere classified	0.604	0.396
M35 Other systemic involvement of connective tissue	0.603	0.397
O91 Infections of breast associated with childbirth	0.602	0.398
O89 Complications of anaesthesia during the puerperium	0.602	0.398
O88 Obstetric embolism	0.602	0.398
O85 Puerperal sepsis	0.602	0.398
M41.9 Scoliosis, unspecified	0.601	0.399
O00-O08 Pregnancy with abortive outcome	0.601	0.399
M05-M14 Inflammatory polyarthropathies	0.601	0.399
J84.0 Alveolar and parietoalveolar conditions	0.600	0.400
S91.3 Open wound of other parts of foot	0.600	0.400
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.599	0.401
O64.1 Obstructed labour due to breech presentation	0.598	0.402
J42 Unspecified chronic bronchitis	0.598	0.402
J09-J18 Influenza and pneumonia	0.598	0.402
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.598	0.402
S98 Traumatic amputation of ankle and foot	0.597	0.402
S97 Crushing injury of ankle and foot	0.597	0.402
S96 Injury of muscle and tendon at ankle and foot level	0.597	0.402
S95 Injury of blood vessels at ankle and foot level	0.597	0.402
S94 Injury of nerves at ankle and foot level	0.597	0.402
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.597	0.402
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.597	0.403
M88 Paget's disease of bone [osteitis deformans]	0.596	0.403
S52.0 Fracture of upper end of ulna	0.595	0.405
Q23 Congenital malformations of aortic and mitral valves	0.594	0.406
T36.0 Penicillins	0.594	0.406
M94 Other disorders of cartilage	0.593	0.406
Q18 Other congenital malformations of face and neck	0.593	0.407
T43.4 Butyrophenone and thioxanthene neuroleptics	0.593	0.407
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.592	0.407
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.592	0.408
S61.9 Open wound of wrist and hand, part unspecified	0.592	0.408
O41.0 Oligohydramnios	0.592	0.408
X20-X29 Contact with venomous animals and plants	0.591	0.409
S20 Superficial injury of thorax	0.591	0.409
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.591	0.409
F60-F69 Disorders of adult personality and behaviour	0.591	0.409
M72 Fibroblastic disorders	0.591	0.409
T50.9 Other and unspecified drugs, medicaments and biological substances	0.590	0.410
Chapter I Certain infectious and parasitic diseases	0.590	0.410
S02.5 Fracture of tooth	0.589	0.411
D80-D89 Certain disorders involving the immune mechanism	0.589	0.411
S19.9 Unspecified injury of neck	0.588	0.412
M82.1 Osteoporosis in endocrine disorders	0.586	0.413
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.586	0.413
M31 Other necrotising vasculopathies	0.586	0.414
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.586	0.414
M34 Systemic sclerosis	0.585	0.415
T23 Burn and corrosion of wrist and hand	0.584	0.415
X50-X57 Overexertion, travel and privation	0.584	0.416
M85.6 Other cyst of bone	0.583	0.416
T90.8 Sequelae of other specified injuries of head	0.583	0.417
T90.3 Sequelae of injury of cranial nerves	0.583	0.417
T90.1 Sequelae of open wound of head	0.583	0.417
T90.0 Sequelae of superficial injury of head	0.583	0.417
O43.9 Placental disorder, unspecified	0.583	0.417
O43.2 Morbidly adherent placenta	0.583	0.417
O43.0 Placental transfusion syndromes	0.583	0.417
M85.8 Other specified disorders of bone density and structure	0.583	0.417
S71 Open wound of hip and thigh	0.583	0.417
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.582	0.418
V40-V49 Car occupant injured in transport accident	0.582	0.418
S99 Other and unspecified injuries of ankle and foot	0.581	0.419
M81.20 Osteoporosis of disuse (Multiple sites)	0.580	0.420
M84.9 Disorder of continuity of bone, unspecified	0.580	0.420
M84.8 Other disorders of continuity of bone	0.580	0.420
M84.4 Pathological fracture, not elsewhere classified	0.580	0.420
M84.3 Stress fracture, not elsewhere classified	0.580	0.420

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations