TreeWAS – Variant ID: rs10540

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L57.0 Actinic keratosis	0.106	0.894	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.063	0.937	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.052	0.947	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.046	0.954	0.000
L57.5 Actinic granuloma	0.046	0.954	0.000
L57.3 Poikiloderma of Civatte	0.046	0.954	0.000
L57.2 Cutis rhomboidalis nuchae	0.046	0.954	0.000
L57.1 Actinic reticuloid	0.046	0.954	0.000
L57.4 Cutis laxa senilis	0.041	0.959	0.000
B34.9 Viral infection, unspecified	0.000	0.972	0.028
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.025	0.975	0.000
M84 Disorders of continuity of bone	0.022	0.978	0.000
M80-M85 Disorders of bone density and structure	0.021	0.979	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.979	0.021
M81.9 Osteoporosis, unspecified	0.021	0.979	0.000
M81 Osteoporosis without pathological fracture	0.021	0.979	0.000
M84.0 Malunion of fracture	0.021	0.979	0.000
M81.98 Osteoporosis, unspecified (Other)	0.020	0.980	0.000
M85 Other disorders of bone density and structure	0.019	0.981	0.000
M84.03 Malunion of fracture (Forearm)	0.018	0.982	0.000
M84.3 Stress fracture, not elsewhere classified	0.018	0.982	0.000
M80 Osteoporosis with pathological fracture	0.018	0.982	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.018	0.982	0.000
L58 Radiodermatitis	0.018	0.982	0.000
L55 Sunburn	0.018	0.982	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.018	0.982	0.000
Z22.3 Carrier of other specified bacterial diseases	0.018	0.982	0.000
M81.0 Postmenopausal osteoporosis	0.017	0.982	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.017	0.983	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.017	0.983	0.000
M85.8 Other specified disorders of bone density and structure	0.017	0.983	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.017	0.983	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.017	0.983	0.000
M84.4 Pathological fracture, not elsewhere classified	0.017	0.983	0.000
M84.8 Other disorders of continuity of bone	0.017	0.983	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.017	0.983	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.016	0.984	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.016	0.984	0.000
M84.9 Disorder of continuity of bone, unspecified	0.016	0.984	0.000
M84.2 Delayed union of fracture	0.016	0.984	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.016	0.984	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.016	0.984	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.016	0.984	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.016	0.984	0.000
M85.6 Other cyst of bone	0.016	0.984	0.000
M84.04 Malunion of fracture (Hand)	0.015	0.984	0.000
M84.01 Malunion of fracture (Shoulder region)	0.015	0.984	0.000
M83 Adult osteomalacia	0.015	0.985	0.000
O16 Unspecified maternal hypertension	0.000	0.985	0.015
M82 Osteoporosis in diseases classified elsewhere	0.015	0.985	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.015	0.985	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.015	0.985	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.015	0.985	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.015	0.985	0.000
M81.8 Other osteoporosis	0.015	0.985	0.000
M81.6 Localised osteoporosis [Lequesne]	0.015	0.985	0.000
M81.5 Idiopathic osteoporosis	0.015	0.985	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.015	0.985	0.000
M81.1 Postoophorectomy osteoporosis	0.015	0.985	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.015	0.985	0.000
M84.09 Malunion of fracture (Site unspecified)	0.015	0.985	0.000
M84.08 Malunion of fracture (Other)	0.015	0.985	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.015	0.985	0.000
M84.02 Malunion of fracture (Upper arm)	0.015	0.985	0.000
M84.00 Malunion of fracture (Multiple sites)	0.015	0.985	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.015	0.985	0.000
M84.06 Malunion of fracture (Lower leg)	0.014	0.986	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.014	0.986	0.000
M81.2 Osteoporosis of disuse	0.014	0.986	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.014	0.986	0.000
B34 Viral infection of unspecified site	0.000	0.986	0.014
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.014	0.986	0.000
M85.9 Disorder of bone density and structure, unspecified	0.014	0.986	0.000
M85.5 Aneurysmal bone cyst	0.014	0.986	0.000
M85.4 Solitary bone cyst	0.014	0.986	0.000
M85.3 Osteitis condensans	0.014	0.986	0.000
M85.2 Hyperostosis of skull	0.014	0.986	0.000
M85.1 Skeletal fluorosis	0.014	0.986	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.014	0.986	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.014	0.986	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.014	0.986	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.014	0.986	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.014	0.986	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.013	0.986	0.000
M85.68 Other cyst of bone (Other)	0.013	0.987	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.013	0.987	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.013	0.987	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.013	0.987	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.013	0.987	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.013	0.987	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.013	0.987	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.013	0.987	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.013	0.987	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.013	0.987	0.000
M80.8 Other osteoporosis with pathological fracture	0.013	0.987	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.013	0.987	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.013	0.987	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.013	0.987	0.000
L55.9 Sunburn, unspecified	0.013	0.987	0.000
L55.8 Other sunburn	0.013	0.987	0.000
L55.2 Sunburn of third degree	0.013	0.987	0.000
L55.1 Sunburn of second degree	0.013	0.987	0.000
L55.0 Sunburn of first degree	0.013	0.987	0.000
L58.9 Radiodermatitis, unspecified	0.013	0.987	0.000
L58.1 Chronic radiodermatitis	0.013	0.987	0.000
L58.0 Acute radiodermatitis	0.013	0.987	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.013	0.987	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.013	0.987	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.013	0.987	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.013	0.987	0.000
M81.4 Drug-induced osteoporosis	0.013	0.987	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.013	0.987	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.013	0.987	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.013	0.987	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.013	0.987	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.013	0.987	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.013	0.987	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.013	0.987	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.013	0.987	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.013	0.987	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.013	0.987	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.013	0.987	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.013	0.987	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.013	0.987	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.013	0.987	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.013	0.987	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.013	0.987	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.013	0.987	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.012	0.987	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.012	0.987	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.012	0.987	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.012	0.987	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.012	0.987	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.012	0.987	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.012	0.987	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.012	0.987	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.012	0.987	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.012	0.987	0.000
M84.88 Other disorders of continuity of bone (Other)	0.012	0.987	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.012	0.987	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.012	0.987	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.012	0.987	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.012	0.987	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.012	0.987	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.012	0.987	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.012	0.987	0.000
L56.4 Polymorphous light eruption	0.012	0.988	0.000
L56.3 Solar urticaria	0.012	0.988	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.012	0.988	0.000
L56.1 Drug photoallergic response	0.012	0.988	0.000
L56.0 Drug phototoxic response	0.012	0.988	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.012	0.988	0.000
M85.0 Fibrous dysplasia (monostotic)	0.012	0.988	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.012	0.988	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.012	0.988	0.000
Z22 Carrier of infectious disease	0.012	0.988	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.988	0.012
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.012	0.988	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.012	0.988	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.012	0.988	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.012	0.988	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.012	0.988	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.012	0.988	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.012	0.988	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.012	0.988	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.012	0.988	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.011	0.988	0.000
M84.28 Delayed union of fracture (Other)	0.011	0.988	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.011	0.988	0.000
M84.26 Delayed union of fracture (Lower leg)	0.011	0.988	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.011	0.988	0.000
M84.24 Delayed union of fracture (Hand)	0.011	0.988	0.000
M84.23 Delayed union of fracture (Forearm)	0.011	0.988	0.000
M84.22 Delayed union of fracture (Upper arm)	0.011	0.988	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.011	0.988	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.011	0.988	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.011	0.988	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.011	0.988	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.011	0.988	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.011	0.988	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.011	0.988	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.011	0.988	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.011	0.988	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.011	0.988	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.011	0.988	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.011	0.988	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.011	0.988	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.011	0.988	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.011	0.988	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.011	0.988	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.011	0.988	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.011	0.988	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.011	0.988	0.000
M85.69 Other cyst of bone (Site unspecified)	0.011	0.988	0.000
M85.66 Other cyst of bone (Lower leg)	0.011	0.988	0.000
M85.64 Other cyst of bone (Hand)	0.011	0.988	0.000
M85.63 Other cyst of bone (Forearm)	0.011	0.988	0.000
M85.62 Other cyst of bone (Upper arm)	0.011	0.988	0.000
M85.61 Other cyst of bone (Shoulder region)	0.011	0.988	0.000
M85.60 Other cyst of bone (Multiple sites)	0.011	0.988	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.011	0.989	0.000
M83.9 Adult osteomalacia, unspecified	0.011	0.989	0.000
M83.8 Other adult osteomalacia	0.011	0.989	0.000
M83.5 Other drug-induced osteomalacia in adults	0.011	0.989	0.000
M83.4 Aluminum bone disease	0.011	0.989	0.000
M83.3 Adult osteomalacia due to malnutrition	0.011	0.989	0.000
M83.2 Adult osteomalacia due to malabsorption	0.011	0.989	0.000
M83.1 Senile osteomalacia	0.011	0.989	0.000
M83.0 Puerperal osteomalacia	0.011	0.989	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.011	0.989	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.011	0.989	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.011	0.989	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.011	0.989	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.011	0.989	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.011	0.989	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.011	0.989	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.011	0.989	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.011	0.989	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.011	0.989	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.011	0.989	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.011	0.989	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.011	0.989	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.011	0.989	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.011	0.989	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.011	0.989	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.011	0.989	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.011	0.989	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.011	0.989	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.011	0.989	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.011	0.989	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.011	0.989	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.011	0.989	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.011	0.989	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.011	0.989	0.000
M81.58 Idiopathic osteoporosis (Other)	0.011	0.989	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.011	0.989	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.011	0.989	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.011	0.989	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.011	0.989	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.011	0.989	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.011	0.989	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.011	0.989	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.011	0.989	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.011	0.989	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.011	0.989	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.011	0.989	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.011	0.989	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.011	0.989	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.011	0.989	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.011	0.989	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.011	0.989	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.011	0.989	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.011	0.989	0.000
M81.89 Other osteoporosis (Site unspecified)	0.011	0.989	0.000
M81.88 Other osteoporosis (Other)	0.011	0.989	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.011	0.989	0.000
M81.86 Other osteoporosis (Lower leg)	0.011	0.989	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.011	0.989	0.000
M81.84 Other osteoporosis (Hand)	0.011	0.989	0.000
M81.83 Other osteoporosis (Forearm)	0.011	0.989	0.000
M81.82 Other osteoporosis (Upper arm)	0.011	0.989	0.000
M81.81 Other osteoporosis (Shoulder region)	0.011	0.989	0.000
M81.80 Other osteoporosis (Multiple sites)	0.011	0.989	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.989	0.011
M82.1 Osteoporosis in endocrine disorders	0.011	0.989	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.011	0.989	0.000
W20-W49 Exposure to inanimate mechanical forces	0.011	0.989	0.000
B34.8 Other viral infections of unspecified site	0.000	0.989	0.011
M81.29 Osteoporosis of disuse (Site unspecified)	0.010	0.989	0.000
M81.28 Osteoporosis of disuse (Other)	0.010	0.989	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.010	0.989	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.010	0.989	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.010	0.989	0.000
M81.24 Osteoporosis of disuse (Hand)	0.010	0.989	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.010	0.989	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.010	0.989	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.010	0.989	0.000
B34.3 Parvovirus infection, unspecified	0.000	0.989	0.010
B34.2 Coronavirus infection, unspecified	0.000	0.989	0.010
B34.1 Enterovirus infection, unspecified	0.000	0.989	0.010
B34.0 Adenovirus infection, unspecified	0.000	0.989	0.010
W22 Striking against or struck by other objects	0.010	0.989	0.000
O14.9 Preeclampsia, unspecified	0.000	0.990	0.010
M85.65 Other cyst of bone (Pelvic region and thigh)	0.010	0.990	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.010	0.990	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.010	0.990	0.000
M85.18 Skeletal fluorosis (Other)	0.010	0.990	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.010	0.990	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.010	0.990	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.010	0.990	0.000
M85.14 Skeletal fluorosis (Hand)	0.010	0.990	0.000
M85.13 Skeletal fluorosis (Forearm)	0.010	0.990	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.010	0.990	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.010	0.990	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.010	0.990	0.000
M85.29 Hyperostosis of skull-Site unspec	0.010	0.990	0.000
M85.28 Hyperostosis of skull-Other	0.010	0.990	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.010	0.990	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.010	0.990	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.010	0.990	0.000
M85.24 Hyperostosis of skull-Hand	0.010	0.990	0.000
M85.23 Hyperostosis of skull-Forearm	0.010	0.990	0.000
M85.22 Hyperostosis of skull-Upper arm	0.010	0.990	0.000
M85.21 Hyperostosis of skull-Shldr region	0.010	0.990	0.000
M85.20 Hyperostosis of skull-Mult sites	0.010	0.990	0.000
M85.39 Osteitis condensans (Site unspecified)	0.010	0.990	0.000
M85.38 Osteitis condensans (Other)	0.010	0.990	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.010	0.990	0.000
M85.36 Osteitis condensans (Lower leg)	0.010	0.990	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.010	0.990	0.000
M85.34 Osteitis condensans (Hand)	0.010	0.990	0.000
M85.33 Osteitis condensans (Forearm)	0.010	0.990	0.000
M85.32 Osteitis condensans (Upper arm)	0.010	0.990	0.000
M85.31 Osteitis condensans (Shoulder region)	0.010	0.990	0.000
M85.30 Osteitis condensans (Multiple sites)	0.010	0.990	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.010	0.990	0.000
M85.48 Solitary bone cyst (Other)	0.010	0.990	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.010	0.990	0.000
M85.46 Solitary bone cyst (Lower leg)	0.010	0.990	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.010	0.990	0.000
M85.44 Solitary bone cyst (Hand)	0.010	0.990	0.000
M85.43 Solitary bone cyst (Forearm)	0.010	0.990	0.000
M85.42 Solitary bone cyst (Upper arm)	0.010	0.990	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.010	0.990	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.010	0.990	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.010	0.990	0.000
M85.58 Aneurysmal bone cyst (Other)	0.010	0.990	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.010	0.990	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.010	0.990	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.010	0.990	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.010	0.990	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.010	0.990	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.010	0.990	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.010	0.990	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.010	0.990	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.010	0.990	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.010	0.990	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.010	0.990	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.010	0.990	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.010	0.990	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.010	0.990	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.010	0.990	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.010	0.990	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.010	0.990	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.010	0.990	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.010	0.990	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
W29 Contact with other powered hand tools and household machinery	0.010	0.990	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.010	0.990	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.010	0.990	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.010	0.990	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
Z22.5 Carrier of viral hepatitis	0.010	0.990	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.009	0.990	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.009	0.990	0.000
M81.48 Drug-induced osteoporosis (Other)	0.009	0.990	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.009	0.990	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.009	0.990	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.009	0.990	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.009	0.990	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.009	0.990	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.009	0.990	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.009	0.990	0.000
B34.4 Papovirus infection, unspecified	0.000	0.990	0.009
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.990	0.010
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.009	0.991	0.000
W22.9 Unspecified place	0.009	0.991	0.000
W45 Foreign body or object entering through skin	0.009	0.991	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.009	0.991	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.009	0.991	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.009	0.991	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.009	0.991	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.009	0.991	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.009	0.991	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.009	0.991	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.009	0.991	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.009	0.991	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.009	0.991	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.009	0.991	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.009	0.991	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.009	0.991	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.991	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.009	0.991	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.009	0.991	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.009	0.991	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.009	0.991	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.009	0.991	0.000
W44 Foreign body entering into or through eye or natural orifice	0.009	0.991	0.000
Z22.9 Carrier of infectious disease, unspecified	0.009	0.991	0.000
Z22.8 Carrier of other infectious diseases	0.009	0.991	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.009	0.991	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.009	0.991	0.000
Z22.2 Carrier of diphtheria	0.009	0.991	0.000
Z22.0 Carrier of typhoid	0.009	0.991	0.000
W29.9 Unspecified place	0.009	0.991	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.009	0.991	0.000
O15 Eclampsia	0.000	0.991	0.009
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.991	0.009
W22.5 Trade and service area	0.009	0.991	0.000
W25 Contact with sharp glass	0.009	0.991	0.000
W28 Contact with powered lawn mower	0.009	0.991	0.000
O14.1 Severe preeclampsia	0.000	0.991	0.009
W22.3 Sports and athletics area	0.009	0.991	0.000
W26 Contact with knife, sword or dagger	0.008	0.991	0.000
O14.0 Moderate preeclampsia	0.000	0.991	0.008
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.991	0.008
W23 Caught, crushed, jammed or pinched in or between objects	0.008	0.991	0.000
W20 Struck by thrown, projected or falling object	0.008	0.992	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.008	0.992	0.000
M83.08 Puerperal osteomalacia (Other)	0.008	0.992	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.008	0.992	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.008	0.992	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.008	0.992	0.000
M83.04 Puerperal osteomalacia (Hand)	0.008	0.992	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.008	0.992	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.008	0.992	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.008	0.992	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.008	0.992	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.008	0.992	0.000
M83.18 Senile osteomalacia (Other)	0.008	0.992	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.008	0.992	0.000
M83.16 Senile osteomalacia (Lower leg)	0.008	0.992	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.008	0.992	0.000
M83.14 Senile osteomalacia (Hand)	0.008	0.992	0.000
M83.13 Senile osteomalacia (Forearm)	0.008	0.992	0.000
M83.12 Senile osteomalacia (Upper arm)	0.008	0.992	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.008	0.992	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.008	0.992	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.008	0.992	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.008	0.992	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.008	0.992	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.008	0.992	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.008	0.992	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.008	0.992	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.008	0.992	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.008	0.992	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.008	0.992	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.008	0.992	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.008	0.992	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.008	0.992	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.008	0.992	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.008	0.992	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.008	0.992	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.008	0.992	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.008	0.992	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.008	0.992	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.008	0.992	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.008	0.992	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.008	0.992	0.000
M83.48 Aluminium bone disease (Other)	0.008	0.992	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.008	0.992	0.000
M83.46 Aluminium bone disease (Lower leg)	0.008	0.992	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.008	0.992	0.000
M83.44 Aluminium bone disease (Hand)	0.008	0.992	0.000
M83.43 Aluminium bone disease (Forearm)	0.008	0.992	0.000
M83.42 Aluminium bone disease (Upper arm)	0.008	0.992	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.008	0.992	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.008	0.992	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.008	0.992	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.008	0.992	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.008	0.992	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.008	0.992	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations