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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10748180
log Bayes Factor = 0.0453805
Chromosome 12   position 72,071,045  (GRCh37) Explore rs10748180 on Ensembl!
Variant rs10748180 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.050 0.950 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.049 0.951 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.049 0.951 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.048 0.952 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.047 0.953 0.000
T40.2 Other opioids
0.047 0.953 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.045 0.955 0.000
K60.3 Anal fistula
0.042 0.958 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.041 0.959 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.041 0.959 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.041 0.959 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.041 0.959 0.000
T43.6 Psychostimulants with abuse potential
0.039 0.961 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.039 0.961 0.000
K60 Fissure and fistula of anal and rectal regions
0.038 0.962 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.038 0.962 0.000
T40.3 Methadone
0.038 0.962 0.000
T40.5 Cocaine
0.037 0.963 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.037 0.963 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.037 0.963 0.000
K60.5 Anorectal fistula
0.037 0.963 0.000
K60.0 Acute anal fissure
0.036 0.964 0.000
T43.9 Psychotropic drug, unspecified
0.036 0.964 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.036 0.964 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.035 0.964 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.035 0.965 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.035 0.965 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.035 0.965 0.000
K70.1 Alcoholic hepatitis
0.035 0.965 0.000
T46.1 Calcium-channel blockers
0.035 0.965 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.035 0.965 0.000
K60.1 Chronic anal fissure
0.035 0.965 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.035 0.965 0.000
K70 Alcoholic liver disease
0.035 0.965 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.035 0.965 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.034 0.966 0.000
T40.8 Lysergide [LSD]
0.034 0.966 0.000
T40.7 Cannabis (derivatives)
0.034 0.966 0.000
T40.1 Heroin
0.034 0.966 0.000
T40.0 Opium
0.034 0.966 0.000
T45.2 Vitamins, not elsewhere classified
0.034 0.966 0.000
T42.1 Iminostilbenes
0.034 0.966 0.000
T42.0 Hydantoin derivatives
0.033 0.967 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.033 0.967 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.033 0.967 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.033 0.967 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.033 0.967 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.033 0.967 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.033 0.967 0.000
T44.0 Anticholinesterase agents
0.033 0.967 0.000
T36 Poisoning by systemic antibiotics
0.032 0.968 0.000
K70.3 Alcoholic cirrhosis of liver
0.032 0.968 0.000
T45.0 Antiallergic and antiemetic drugs
0.032 0.968 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.032 0.968 0.000
T42.4 Benzodiazepines
0.031 0.969 0.000
K70.4 Alcoholic hepatic failure
0.031 0.969 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.031 0.969 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.030 0.970 0.000
K70.0 Alcoholic fatty liver
0.030 0.970 0.000
T45.5 Anticoagulants
0.030 0.970 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.030 0.970 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.030 0.970 0.000
T46.7 Peripheral vasodilators
0.030 0.970 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.030 0.970 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.030 0.970 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.029 0.970 0.000
T45.8 Other primarily systemic and haematological agents
0.029 0.970 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.029 0.970 0.000
T45.6 Fibrinolysis-affecting drugs
0.029 0.970 0.000
T45.4 Iron and its compounds
0.029 0.970 0.000
T45.3 Enzymes, not elsewhere classified
0.029 0.970 0.000
T50.4 Drugs affecting uric acid metabolism
0.029 0.970 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.029 0.970 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.029 0.970 0.000
T42.3 Barbiturates
0.029 0.970 0.000
T42.2 Succinimides and oxazolidinediones
0.029 0.970 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.029 0.971 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.029 0.971 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.029 0.971 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.028 0.971 0.000
T40.6 Other and unspecified narcotics
0.028 0.972 0.000
K76.9 Liver disease, unspecified
0.028 0.972 0.000
T50.7 Analeptics and opioid receptor antagonists
0.028 0.972 0.000
T50.5 Appetite depressants
0.028 0.972 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.028 0.972 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.028 0.972 0.000
T50.1 Loop [high-ceiling] diuretics
0.028 0.972 0.000
T50.0 Mineralocorticoids and their antagonists
0.028 0.972 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.028 0.972 0.000
T40.4 Other synthetic narcotics
0.028 0.972 0.000
J81 Pulmonary oedema
0.028 0.972 0.000
K76 Other diseases of liver
0.028 0.972 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.027 0.973 0.000
K70-K77 Diseases of liver
0.027 0.973 0.000
T50.8 Diagnostic agents
0.027 0.973 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.027 0.973 0.000
T48.5 Anti-common-cold drugs
0.027 0.973 0.000
T48.4 Expectorants
0.027 0.973 0.000
T48.3 Antitussives
0.027 0.973 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.027 0.973 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.027 0.973 0.000
T48.0 Oxytocic drugs
0.027 0.973 0.000
T47.0 Histamine H(2)-receptor antagonists
0.026 0.974 0.000
K76.8 Other specified diseases of liver
0.026 0.974 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.026 0.974 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.026 0.974 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.026 0.974 0.000
T47.7 Emetics
0.026 0.974 0.000
T47.6 Antidiarrhoeal drugs
0.026 0.974 0.000
T47.5 Digestants
0.026 0.974 0.000
T47.4 Other laxatives
0.026 0.974 0.000
T47.3 Saline and osmotic laxatives
0.026 0.974 0.000
T47.2 Stimulant laxatives
0.026 0.974 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.026 0.974 0.000
T41.5 Therapeutic gases
0.025 0.974 0.000
T41.4 Anaesthetic, unspecified
0.025 0.974 0.000
T41.3 Local anaesthetics
0.025 0.974 0.000
T41.2 Other and unspecified general anaesthetics
0.025 0.974 0.000
T41.1 Intravenous anaesthetics
0.025 0.974 0.000
T41.0 Inhaled anaesthetics
0.025 0.974 0.000
T49.9 Topical agent, unspecified
0.025 0.974 0.000
T49.8 Other topical agents
0.025 0.974 0.000
T49.7 Dental drugs, topically applied
0.025 0.974 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.025 0.974 0.000
T49.5 Ophthalmological drugs and preparations
0.025 0.974 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.025 0.974 0.000
T49.3 Emollients, demulcents and protectants
0.025 0.974 0.000
T49.2 Local astringents and local detergents
0.025 0.974 0.000
T49.1 Antipruritics
0.025 0.974 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.025 0.974 0.000
T43.2 Other and unspecified antidepressants
0.025 0.974 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.025 0.975 0.000
T37.5 Antiviral drugs
0.025 0.975 0.000
T37.4 Anthelminthics
0.025 0.975 0.000
T37.3 Other antiprotozoal drugs
0.025 0.975 0.000
T37.1 Antimycobacterial drugs
0.025 0.975 0.000
T37.0 Sulphonamides
0.025 0.975 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.025 0.975 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.025 0.975 0.000
T38.9 Other and unspecified hormone antagonists
0.025 0.975 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.025 0.975 0.000
T38.7 Androgens and anabolic congeners
0.025 0.975 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.025 0.975 0.000
T38.5 Other oestrogens and progestogens
0.025 0.975 0.000
T38.4 Oral contraceptives
0.025 0.975 0.000
T38.2 Antithyroid drugs
0.025 0.975 0.000
T38.0 Glucocorticoids and synthetic analogues
0.025 0.975 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.975 0.025
K70.9 Alcoholic liver disease, unspecified
0.024 0.976 0.000
T38.1 Thyroid hormones and substitutes
0.023 0.977 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.023 0.977 0.000
T36.9 Systemic antibiotic, unspecified
0.023 0.977 0.000
T36.8 Other systemic antibiotics
0.023 0.977 0.000
T36.7 Antifungal antibiotics, systemically used
0.023 0.977 0.000
T36.6 Rifamycins
0.023 0.977 0.000
T36.5 Aminoglycosides
0.023 0.977 0.000
T36.4 Tetracyclines
0.023 0.977 0.000
T36.3 Macrolides
0.023 0.977 0.000
T36.2 Chloramphenicol group
0.023 0.977 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.023 0.977 0.000
K72 Hepatic failure, not elsewhere classified
0.023 0.977 0.000
K60.4 Rectal fistula
0.023 0.977 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.023 0.977 0.000
K76.1 Chronic passive congestion of liver
0.022 0.978 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.022 0.978 0.000
K72.0 Acute and subacute hepatic failure
0.021 0.978 0.000
J84 Other interstitial pulmonary diseases
0.021 0.979 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.021 0.979 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.021 0.979 0.000
K76.6 Portal hypertension
0.020 0.980 0.000
K76.5 Hepatic veno-occlusive disease
0.020 0.980 0.000
K76.4 Peliosis hepatis
0.020 0.980 0.000
K76.3 Infarction of liver
0.020 0.980 0.000
K76.2 Central haemorrhagic necrosis of liver
0.020 0.980 0.000
K73 Chronic hepatitis, not elsewhere classified
0.020 0.980 0.000
T36.0 Penicillins
0.019 0.980 0.000
K77 Liver disorders in diseases classified elsewhere
0.019 0.980 0.000
K71 Toxic liver disease
0.018 0.981 0.000
K76.7 Hepatorenal syndrome
0.019 0.981 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.018 0.982 0.000
K74 Fibrosis and cirrhosis of liver
0.018 0.982 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.018 0.982 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.017 0.983 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.983 0.017
K72.1 Chronic hepatic failure
0.016 0.984 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.984 0.016
O80.9 Single spontaneous delivery, unspecified
0.000 0.984 0.016
K73.2 Chronic active hepatitis, not elsewhere classified
0.016 0.984 0.000
M45 Ankylosing spondylitis
0.016 0.984 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.984 0.016
Z43 Attention to artificial openings
0.000 0.984 0.016
J84.0 Alveolar and parietoalveolar conditions
0.015 0.984 0.000
Z43.1 Attention to gastrostomy
0.000 0.984 0.015
R07.0 Pain in throat
0.000 0.985 0.015
O20.9 Haemorrhage in early pregnancy, unspecified
0.015 0.985 0.000
K72.9 Hepatic failure, unspecified
0.015 0.985 0.000
K74.1 Hepatic sclerosis
0.014 0.985 0.000
J84.8 Other specified interstitial pulmonary diseases
0.014 0.986 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.014 0.986 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.014 0.986 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.014 0.986 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.014 0.986 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.014 0.986 0.000
K74.6 Other and unspecified cirrhosis of liver
0.014 0.986 0.000
X62.9 Unspecified place
0.014 0.986 0.000
Z43.2 Attention to ileostomy
0.000 0.986 0.014
Z43.3 Attention to colostomy
0.000 0.986 0.014
Z43.8 Attention to other artificial openings
0.000 0.986 0.014
K74.3 Primary biliary cirrhosis
0.014 0.986 0.000
K71.9 Toxic liver disease, unspecified
0.013 0.986 0.000
K71.8 Toxic liver disease with other disorders of liver
0.013 0.986 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.013 0.986 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.013 0.986 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.013 0.986 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.013 0.986 0.000
K71.2 Toxic liver disease with acute hepatitis
0.013 0.986 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.013 0.986 0.000
K71.0 Toxic liver disease with cholestasis
0.013 0.986 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.000 0.986 0.014
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.013 0.987 0.000
O20 Haemorrhage in early pregnancy
0.013 0.987 0.000
K74.4 Secondary biliary cirrhosis
0.013 0.987 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.013 0.987 0.000
K74.5 Biliary cirrhosis, unspecified
0.013 0.987 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.013 0.987 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.012 0.987 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.000 0.987 0.013
O20.0 Threatened abortion
0.013 0.987 0.000
K73.9 Chronic hepatitis, unspecified
0.012 0.988 0.000
Z43.5 Attention to cyctostomy
0.000 0.988 0.012
M45.X2 Ankylosing spondylitis (Cervical region)
0.012 0.988 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.012 0.988 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.012 0.988 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.012 0.988 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.012 0.988 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.012 0.988 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.012 0.988 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.000 0.988 0.011
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.000 0.988 0.011
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.988 0.011
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.000 0.988 0.011
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.000 0.988 0.011
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.000 0.988 0.011
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.000 0.988 0.011
Z43.9 Attention to unspecified artificial opening
0.000 0.989 0.011
Z43.7 Attention to artificial vagina
0.000 0.989 0.011
M45.X6 Ankylosing spondylitis (Lumbar region)
0.011 0.989 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.011 0.989 0.000
O24 Diabetes mellitus in pregnancy
0.011 0.989 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.989 0.011
O20-O29 Other maternal disorders predominantly related to pregnancy
0.011 0.989 0.000
J80 Adult respiratory distress syndrome
0.011 0.989 0.000
Y45.0 Opioids and related analgesics
0.011 0.989 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.010 0.989 0.000
M48.02 Spinal stenosis (Cervical region)
0.011 0.989 0.000
M48 Other spondylopathies
0.010 0.990 0.000
M48.0 Spinal stenosis
0.010 0.990 0.000
Z43.0 Attention to tracheostomy
0.000 0.990 0.010
M45-M49 Spondylopathies
0.010 0.990 0.000
M80 Osteoporosis with pathological fracture
0.000 0.990 0.010
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.000 0.990 0.010
M48.00 Spinal stenosis (Multiple sites in spine)
0.010 0.990 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.010 0.990 0.000
O24.9 Diabetes mellitus in pregnancy, unspecified
0.010 0.990 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.010 0.990 0.000
M48.09 Spinal stenosis (Site unspecified)
0.010 0.990 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.009 0.990 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.000 0.991 0.009
T39.4 Antirheumatics, not elsewhere classified
0.009 0.991 0.000
T39.2 Pyrazolone derivatives
0.009 0.991 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.009 0.991 0.000
O21 Excessive vomiting in pregnancy
0.009 0.991 0.000
M48.04 Spinal stenosis (Thoracic region)
0.009 0.991 0.000
M00.9 Pyogenic arthritis, unspecified
0.009 0.991 0.000
M89 Other disorders of bone
0.009 0.991 0.000
O23 Infections of genito-urinary tract in pregnancy
0.009 0.991 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.008 0.991 0.000
O22 Venous complications in pregnancy
0.008 0.991 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.992 0.008
M89.8 Other specified disorders of bone
0.008 0.992 0.000
O20.8 Other haemorrhage in early pregnancy
0.008 0.992 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.008 0.992 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.992 0.008
O24.3 Pre-existing diabetes mellitus, unspecified
0.008 0.992 0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus
0.008 0.992 0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent
0.008 0.992 0.000
K74.0 Hepatic fibrosis
0.008 0.992 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.008 0.992 0.000
M48.9 Spondylopathy, unspecified
0.008 0.992 0.000
M86-M90 Other osteopathies
0.008 0.992 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.008 0.992 0.000
N64.5 Other signs and symptoms in breast
0.000 0.992 0.008
M80.0 Postmenopausal osteoporosis with pathological fracture
0.000 0.992 0.008
N47 Redundant prepuce, phimosis and paraphimosis
0.008 0.992 0.000
O29 Complications of anaesthesia during pregnancy
0.008 0.992 0.000
O25 Malnutrition in pregnancy
0.008 0.992 0.000
M89.0 Algoneurodystrophy
0.008 0.992 0.000
M48.4 Fatigue fracture of vertebra
0.008 0.992 0.000
M48.3 Traumatic spondylopathy
0.008 0.992 0.000
M48.2 Kissing spine
0.008 0.992 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.008 0.992 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.008 0.992 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.008 0.992 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.008 0.992 0.000
O21.0 Mild hyperemesis gravidarum
0.008 0.992 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.008 0.992 0.000
O28 Abnormal findings on antenatal screening of mother
0.008 0.992 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.008 0.992 0.000
X62.8 Other specified place
0.007 0.992 0.000
F60.9 Personality disorder, unspecified
0.008 0.992 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.000 0.992 0.007
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.992 0.008
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.992 0.007
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.992 0.007
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.992 0.007
M80.8 Other osteoporosis with pathological fracture
0.000 0.992 0.007
M00 Pyogenic arthritis
0.007 0.992 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.007 0.993 0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.007 0.993 0.000
O21.2 Late vomiting of pregnancy
0.007 0.993 0.000
M86 Osteomyelitis
0.007 0.993 0.000
X62.0 Home
0.007 0.993 0.000
X62.7 Farm
0.007 0.993 0.000
X62.6 Industrial and construction area
0.007 0.993 0.000
X62.5 Trade and service area
0.007 0.993 0.000
X62.4 Street and highway
0.007 0.993 0.000
X62.3 Sports and athletics area
0.007 0.993 0.000
X62.2 School, other institution and public administrative area
0.007 0.993 0.000
X62.1 Residential institution
0.007 0.993 0.000
M48.8 Other specified spondylopathies
0.007 0.993 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.007 0.993 0.000
M89.88 Other specified disorders of bone (Other)
0.007 0.993 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.007 0.993 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.000 0.993 0.007
F81 Specific developmental disorders of scholastic skills
0.007 0.993 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.000 0.993 0.007
O21.9 Vomiting of pregnancy, unspecified
0.007 0.993 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.007 0.993 0.000
O22.4 Haemorrhoids in pregnancy
0.007 0.993 0.000
O80 Single spontaneous delivery
0.000 0.993 0.007
M89.4 Other hypertrophic osteo-arthropathy
0.007 0.993 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.007 0.993 0.000
M49 Spondylopathies in diseases classified elsewhere
0.007 0.993 0.000
M90 Osteopathies in diseases classified elsewhere
0.007 0.993 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.007 0.993 0.000
M86.9 Osteomyelitis, unspecified
0.007 0.993 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.007 0.993 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.007 0.993 0.000
M88 Paget's disease of bone [osteitis deformans]
0.007 0.993 0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.007 0.993 0.000
M89.83 Other specified disorders of bone (Forearm)
0.007 0.993 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.007 0.993 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.007 0.993 0.000
M00.98 Pyogenic arthritis, unspecified (Other)
0.007 0.993 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.007 0.993 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.007 0.993 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.007 0.993 0.000
M89.3 Hypertrophy of bone
0.007 0.993 0.000
M17.0 Primary gonarthrosis, bilateral
0.000 0.993 0.007
O23.5 Infections of the genital tract in pregnancy
0.007 0.993 0.000
O21.8 Other vomiting complicating pregnancy
0.006 0.993 0.000
M89.6 Osteopathy after poliomyelitis
0.006 0.993 0.000
M89.2 Other disorders of bone development and growth
0.006 0.993 0.000
M89.1 Epiphyseal arrest
0.006 0.993 0.000
T39.0 Salicylates
0.006 0.993 0.000
M00-M03 Infectious arthropathies
0.006 0.993 0.000
O80.8 Other single spontaneous delivery
0.000 0.993 0.006
O23.4 Unspecified infection of urinary tract in pregnancy
0.006 0.993 0.000
F60 Specific personality disorders
0.007 0.993 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.007 0.993 0.000
M89.9 Disorder of bone, unspecified
0.007 0.993 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.006 0.994 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.000 0.994 0.006
M89.09 Algoneurodystrophy (Site unspecified)
0.006 0.994 0.000
O23.3 Infections of other parts of urinary tract in pregnancy
0.006 0.994 0.000
O23.2 Infections of urethra in pregnancy
0.006 0.994 0.000
O23.1 Infections of bladder in pregnancy
0.006 0.994 0.000
O23.0 Infections of kidney in pregnancy
0.006 0.994 0.000
O22.9 Venous complication in pregnancy, unspecified
0.006 0.994 0.000
O22.8 Other venous complications in pregnancy
0.006 0.994 0.000
O22.5 Cerebral venous thrombosis in pregnancy
0.006 0.994 0.000
O22.3 Deep phlebothrombosis in pregnancy
0.006 0.994 0.000
O22.2 Superficial thrombophlebitis in pregnancy
0.006 0.994 0.000
O22.1 Genital varices in pregnancy
0.006 0.994 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.006 0.994 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.006 0.994 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.006 0.994 0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.006 0.994 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.006 0.994 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.006 0.994 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.006 0.994 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.006 0.994 0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.000 0.994 0.006
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.000 0.994 0.006
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.000 0.994 0.006
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.000 0.994 0.006
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.994 0.006
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.000 0.994 0.006
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.000 0.994 0.006
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.000 0.994 0.006
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.000 0.994 0.006
O22.0 Varicose veins of lower extremity in pregnancy
0.006 0.994 0.000
M46 Other inflammatory spondylopathies
0.006 0.994 0.000
O28.0 Abnormal haematological finding on antenatal screening of mother
0.006 0.994 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.006 0.994 0.000
M99 Biomechanical lesions, not elsewhere classified
0.006 0.994 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.006 0.994 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.006 0.994 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.006 0.994 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.006 0.994 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.006 0.994 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.006 0.994 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.006 0.994 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.006 0.994 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.000 0.994 0.006
X60-X84 Intentional self-harm
0.006 0.994 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.006 0.994 0.000
M89.04 Algoneurodystrophy (Hand)
0.006 0.994 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.006 0.994 0.000
M51.8 Other specified intervertebral disk disorders
0.006 0.994 0.000
M89.5 Osteolysis
0.006 0.994 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.006 0.994 0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.000 0.994 0.006
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.000 0.994 0.006
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.000 0.994 0.006
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.000 0.994 0.006
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.994 0.006
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.000 0.994 0.006
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.000 0.994 0.006
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.000 0.994 0.006
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.000 0.994 0.006
O29.9 Complication of anaesthesia during pregnancy, unspecified
0.006 0.994 0.000
O29.8 Other complications of anaesthesia during pregnancy
0.006 0.994 0.000
O29.6 Failed or difficult intubation during pregnancy
0.006 0.994 0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy
0.006 0.994 0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy
0.006 0.994 0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy
0.006 0.994 0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy
0.006 0.994 0.000
O29.1 Cardiac complications of anaesthesia during pregnancy
0.006 0.994 0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy
0.006 0.994 0.000
M89.08 Algoneurodystrophy (Other)
0.006 0.994 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.006 0.994 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.006 0.994 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.006 0.994 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.006 0.994 0.000
M99.5 Intervertebral disk stenosis of neural canal
0.006 0.994 0.000
M87 Osteonecrosis
0.006 0.994 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.006 0.994 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.006 0.994 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.006 0.994 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.006 0.994 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.006 0.994 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.006 0.994 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.006 0.994 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.006 0.994 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.006 0.994 0.000
M48.29 Kissing spine (Site unspecified)
0.006 0.994 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.27 Kissing spine (Lumbosacral region)
0.006 0.994 0.000
M48.26 Kissing spine (Lumbar region)
0.006 0.994 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.006 0.994 0.000
M48.24 Kissing spine (Thoracic region)
0.006 0.994 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.006 0.994 0.000
M48.22 Kissing spine (Cervical region)
0.006 0.994 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.006 0.994 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.006 0.994 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.006 0.994 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.006 0.994 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.006 0.994 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.006 0.994 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.006 0.994 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.006 0.994 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.006 0.994 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.006 0.994 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.006 0.994 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.006 0.994 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.006 0.994 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.006 0.994 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.006 0.994 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.006 0.994 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.006 0.994 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.006 0.994 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.006 0.994 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.006 0.994 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.006 0.994 0.000
M89.84 Other specified disorders of bone (Hand)
0.006 0.994 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.006 0.994 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.006 0.994 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother
0.006 0.994 0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified
0.006 0.994 0.000
O28.8 Other abnormal findings on antenatal screening of mother
0.006 0.994 0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother
0.006 0.994 0.000
O28.4 Abnormal radiological finding on antenatal screening of mother
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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