TreeWAS – Variant ID: rs10762651

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S01 Open wound of head	0.000	0.148	0.852
S01.8 Open wound of other parts of head	0.000	0.170	0.830
S01.0 Open wound of scalp	0.000	0.186	0.814
S01.3 Open wound of ear	0.000	0.215	0.785
S01.9 Open wound of head, part unspecified	0.000	0.216	0.784
S01.5 Open wound of lip and oral cavity	0.000	0.252	0.748
S01.4 Open wound of cheek and temporomandibular area	0.000	0.258	0.742
S00-S09 Injuries to the head	0.000	0.275	0.725
S06 Intracranial injury	0.000	0.329	0.671
S01.7 Multiple open wounds of head	0.000	0.331	0.669
S01.2 Open wound of nose	0.000	0.375	0.625
S02 Fracture of skull and facial bones	0.000	0.381	0.619
S01.1 Open wound of eyelid and periocular area	0.000	0.399	0.600
S05 Injury of eye and orbit	0.000	0.401	0.599
S06.3 Focal brain injury	0.000	0.407	0.592
S00 Superficial injury of head	0.000	0.444	0.556
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.450	0.550
S02.8 Fractures of other skull and facial bones	0.000	0.458	0.542
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.464	0.536
S06.4 Epidural haemorrhage	0.000	0.478	0.522
S08 Traumatic amputation of part of head	0.000	0.480	0.520
S07 Crushing injury of head	0.000	0.480	0.520
S04 Injury of cranial nerves	0.000	0.480	0.520
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.480	0.520
S06.5 Traumatic subdural haemorrhage	0.000	0.488	0.512
S06.0 Concussion	0.000	0.488	0.512
S02.4 Fracture of malar and maxillary bones	0.000	0.490	0.510
S00.7 Multiple superficial injuries of head	0.000	0.491	0.509
S05.1 Contusion of eyeball and orbital tissues	0.000	0.494	0.506
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.507	0.492
S06.8 Other intracranial injuries	0.000	0.509	0.491
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.513	0.487
S06.7 Intracranial injury with prolonged coma	0.000	0.519	0.481
S06.1 Traumatic cerebral oedema	0.000	0.519	0.481
S02.0 Fracture of vault of skull	0.000	0.529	0.471
S06.9 Intracranial injury, unspecified	0.000	0.531	0.469
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.536	0.464
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.537	0.462
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.539	0.461
S02.1 Fracture of base of skull	0.000	0.539	0.461
S02.6 Fracture of mandible	0.000	0.550	0.450
S02.7 Multiple fractures involving skull and facial bones	0.000	0.556	0.444
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.569	0.431
S05.7 Avulsion of eye	0.000	0.570	0.429
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.570	0.429
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.570	0.429
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.570	0.429
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.570	0.429
S05.8 Other injuries of eye and orbit	0.000	0.573	0.426
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.575	0.425
S02.5 Fracture of tooth	0.000	0.584	0.416
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.585	0.414
S02.3 Fracture of orbital floor	0.000	0.588	0.412
S06.2 Diffuse brain injury	0.000	0.593	0.407
S00.5 Superficial injury of lip and oral cavity	0.000	0.598	0.402
S00.4 Superficial injury of ear	0.000	0.601	0.399
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.602	0.398
S06.00 Concussion (without open intracranial wound)	0.000	0.602	0.398
S00.3 Superficial injury of nose	0.000	0.604	0.396
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.605	0.394
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.608	0.392
S05.9 Injury of eye and orbit, part unspecified	0.000	0.610	0.390
S02.81 Fractures of other skull and facial bones (open)	0.000	0.611	0.388
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.626	0.374
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.627	0.373
S03.4 Sprain and strain of jaw	0.000	0.627	0.373
S03.3 Dislocation of other and unspecified parts of head	0.000	0.627	0.373
S03.2 Dislocation of tooth	0.000	0.627	0.373
S03.1 Dislocation of septal cartilage of nose	0.000	0.627	0.373
S03.0 Dislocation of jaw	0.000	0.627	0.373
S04.9 Injury of unspecified cranial nerve	0.000	0.627	0.373
S04.8 Injury of other cranial nerves	0.000	0.627	0.373
S04.7 Injury of accessory nerve	0.000	0.627	0.373
S04.6 Injury of acoustic nerve	0.000	0.627	0.373
S04.5 Injury of facial nerve	0.000	0.627	0.373
S04.4 Injury of abducent nerve	0.000	0.627	0.373
S04.3 Injury of trigeminal nerve	0.000	0.627	0.373
S04.2 Injury of trochlear nerve	0.000	0.627	0.373
S04.1 Injury of oculomotor nerve	0.000	0.627	0.373
S04.0 Injury of optic nerve and pathways	0.000	0.627	0.373
S07.9 Crushing injury of head, part unspecified	0.000	0.627	0.373
S07.8 Crushing injury of other parts of head	0.000	0.627	0.373
S07.1 Crushing injury of skull	0.000	0.627	0.373
S07.0 Crushing injury of face	0.000	0.627	0.373
S08.9 Traumatic amputation of unspecified part of head	0.000	0.627	0.373
S08.8 Traumatic amputation of other parts of head	0.000	0.627	0.373
S08.1 Traumatic amputation of ear	0.000	0.627	0.373
S08.0 Avulsion of scalp	0.000	0.627	0.373
S00.8 Superficial injury of other parts of head	0.000	0.632	0.368
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.633	0.367
S06.01 Concussion (with open intracranial wound)	0.000	0.633	0.367
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.634	0.365
S02.00 Fracture of vault of skull (closed)	0.000	0.635	0.364
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.638	0.362
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.648	0.352
S09 Other and unspecified injuries of head	0.000	0.648	0.352
S00.0 Superficial injury of scalp	0.000	0.648	0.352
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.649	0.350
S00.1 Contusion of eyelid and periocular area	0.000	0.652	0.348
S02.10 Fracture of base of skull (closed)	0.000	0.653	0.347
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.655	0.345
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.655	0.345
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.655	0.345
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.655	0.345
S02.01 Fracture of vault of skull (open)	0.000	0.662	0.337
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.664	0.336
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.668	0.332
S02.11 Fracture of base of skull (open)	0.000	0.670	0.330
S02.60 Fracture of mandible (closed)	0.000	0.672	0.328
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.676	0.324
S02.61 Fracture of mandible (open)	0.000	0.677	0.322
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.682	0.318
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.682	0.318
S02.2 Fracture of nasal bones	0.000	0.687	0.312
S02.51 Fracture of tooth (open)	0.000	0.702	0.298
S02.31 Fracture of orbital floor (open)	0.000	0.704	0.296
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.708	0.292
S02.50 Fracture of tooth (closed)	0.000	0.729	0.270
S02.30 Fracture of orbital floor (closed)	0.000	0.735	0.264
S09.7 Multiple injuries of head	0.000	0.747	0.252
S09.2 Traumatic rupture of ear drum	0.000	0.747	0.252
S09.1 Injury of muscle and tendon of head	0.000	0.747	0.252
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.747	0.252
S00.9 Superficial injury of head, part unspecified	0.000	0.763	0.237
S09.8 Other specified injuries of head	0.000	0.766	0.233
S02.21 Fracture of nasal bones (open)	0.000	0.776	0.224
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.782	0.218
S09.9 Unspecified injury of head	0.000	0.873	0.127
S02.20 Fracture of nasal bones (closed)	0.001	0.907	0.092
K61.0 Anal abscess	0.000	0.933	0.067
K61 Abscess of anal and rectal regions	0.000	0.951	0.049
K61.3 Ischiorectal abscess	0.000	0.953	0.047
K61.4 Intrasphincteric abscess	0.000	0.965	0.035
K61.2 Anorectal abscess	0.000	0.965	0.035
K61.1 Rectal abscess	0.000	0.966	0.034
F10.0 Acute intoxication	0.000	0.968	0.032
D48.5 Skin	0.020	0.980	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.019	0.981	0.000
D48.7 Other specified sites	0.019	0.981	0.000
J18.9 Pneumonia, unspecified	0.018	0.982	0.000
D48.0 Bone and articular cartilage	0.017	0.983	0.000
F31 Bipolar affective disorder	0.017	0.983	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.017	0.983	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.015	0.984	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.015	0.985	0.000
N86 Erosion and ectropion of cervix uteri	0.000	0.985	0.015
F31.7 Bipolar affective disorder, currently in remission	0.014	0.986	0.000
D48.1 Connective and other soft tissue	0.014	0.986	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.014	0.986	0.000
D48.4 Peritoneum	0.014	0.986	0.000
D48.3 Retroperitoneum	0.014	0.986	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.014	0.986	0.000
D45 Polycythaemia vera	0.014	0.986	0.000
F31.9 Bipolar affective disorder, unspecified	0.014	0.986	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.013	0.986	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.013	0.986	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.013	0.987	0.000
F10.1 Harmful use	0.000	0.987	0.013
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.987	0.013
D37-D48 Neoplasms of uncertain or unknown behaviour	0.013	0.987	0.000
D48.6 Breast	0.012	0.988	0.000
F31.8 Other bipolar affective disorders	0.012	0.988	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.011	0.989	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.011	0.989	0.000
H33.3 Retinal breaks without detachment	0.000	0.990	0.010
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.010	0.990	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.010	0.990	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.010	0.990	0.000
F10.8 Other mental and behavioural disorders	0.000	0.990	0.009
F10.7 Residual and late-onset psychotic disorder	0.000	0.990	0.009
F10.6 Amnesic syndrome	0.000	0.990	0.009
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.009	0.991	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.009	0.991	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.009	0.991	0.000
F10.5 Psychotic disorder	0.000	0.991	0.009
E66.8 Other obesity	0.009	0.991	0.000
F10.2 Dependence syndrome	0.000	0.991	0.009
F10.4 Withdrawal state with delirium	0.000	0.991	0.009
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.008	0.992	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.008	0.992	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.008	0.992	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.008	0.992	0.000
D47.1 Chronic myeloproliferative disease	0.008	0.992	0.000
D38.0 Larynx	0.008	0.992	0.000
D44.3 Pituitary gland	0.008	0.992	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.008	0.992	0.000
D47.2 Monoclonal gammopathy	0.008	0.992	0.000
F10.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
D44.9 Endocrine gland, unspecified	0.007	0.993	0.000
D44.8 Pluriglandular involvement	0.007	0.993	0.000
D44.7 Aortic body and other paraganglia	0.007	0.993	0.000
D44.6 Carotid body	0.007	0.993	0.000
D44.5 Pineal gland	0.007	0.993	0.000
D44.4 Craniopharyngeal duct	0.007	0.993	0.000
D44.2 Parathyroid gland	0.007	0.993	0.000
D44.1 Adrenal gland	0.007	0.993	0.000
D44.0 Thyroid gland	0.007	0.993	0.000
D47.4 Osteomyelofibrosis	0.007	0.993	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.007	0.993	0.000
D38.6 Respiratory organ, unspecified	0.007	0.993	0.000
D38.5 Other respiratory organs	0.007	0.993	0.000
D38.4 Thymus	0.007	0.993	0.000
D38.3 Mediastinum	0.007	0.993	0.000
D38.2 Pleura	0.007	0.993	0.000
D40.1 Testis	0.007	0.993	0.000
D42.9 Meninges, unspecified	0.007	0.993	0.000
D42.1 Spinal meninges	0.007	0.993	0.000
D42.0 Cerebral meninges	0.007	0.993	0.000
D46 Myelodysplastic syndromes	0.007	0.993	0.000
D40.9 Male genital organ, unspecified	0.007	0.993	0.000
D40.7 Other male genital organs	0.007	0.993	0.000
D39.9 Female genital organ, unspecified	0.007	0.993	0.000
D39.7 Other female genital organs	0.007	0.993	0.000
D39.2 Placenta	0.007	0.993	0.000
D39.0 Uterus	0.007	0.993	0.000
D40.0 Prostate	0.006	0.993	0.000
D39.1 Ovary	0.006	0.993	0.000
N23 Unspecified renal colic	0.006	0.994	0.000
D37.5 Rectum	0.006	0.994	0.000
Z98.1 Arthrodesis status	0.006	0.994	0.000
D38.1 Trachea, bronchus and lung	0.006	0.994	0.000
D43.9 Central nervous system, unspecified	0.006	0.994	0.000
D43.7 Other parts of central nervous system	0.006	0.994	0.000
D43.4 Spinal cord	0.006	0.994	0.000
D43.3 Cranial nerves	0.006	0.994	0.000
D43.1 Brain, infratentorial	0.006	0.994	0.000
F30-F39 Mood [affective] disorders	0.006	0.994	0.000
N20.2 Calculus of kidney with calculus of ureter	0.006	0.994	0.000
N20 Calculus of kidney and ureter	0.006	0.994	0.000
D37.0 Lip, oral cavity and pharynx	0.006	0.994	0.000
D43.0 Brain, supratentorial	0.005	0.994	0.000
F39 Unspecified mood [affective] disorder	0.006	0.994	0.000
D37.6 Liver, gallbladder and bile ducts	0.005	0.994	0.000
D37.3 Appendix	0.005	0.994	0.000
D37.2 Small intestine	0.005	0.994	0.000
F30 Manic episode	0.005	0.994	0.000
D37.9 Digestive organ, unspecified	0.005	0.995	0.000
D46.7 Other myelodysplastic syndromes	0.005	0.995	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.005	0.995	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.005	0.995	0.000
D46.4 Refractory anaemia, unspecified	0.005	0.995	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.005	0.995	0.000
D46.2 Refractory anaemia with excess of blasts	0.005	0.995	0.000
D46.1 Refractory anaemia with sideroblasts	0.005	0.995	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.005	0.995	0.000
N20.1 Calculus of ureter	0.005	0.995	0.000
I50.9 Heart failure, unspecified	0.005	0.995	0.000
N20-N23 Urolithiasis	0.005	0.995	0.000
D43.2 Brain, unspecified	0.005	0.995	0.000
F30.9 Manic episode, unspecified	0.005	0.995	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.005	0.995	0.000
R73.9 Hyperglycaemia, unspecified	0.005	0.995	0.000
D37.4 Colon	0.005	0.995	0.000
D37.1 Stomach	0.005	0.995	0.000
F30.0 Hypomania	0.005	0.995	0.000
F38 Other mood [affective] disorders	0.004	0.995	0.000
F34 Persistent mood [affective] disorders	0.004	0.996	0.000
N20.0 Calculus of kidney	0.004	0.996	0.000
D37.7 Other digestive organs	0.004	0.996	0.000
N20.9 Urinary calculus, unspecified	0.004	0.996	0.000
F30.8 Other manic episodes	0.004	0.996	0.000
F30.1 Mania without psychotic symptoms	0.004	0.996	0.000
H91.9 Hearing loss, unspecified	0.004	0.996	0.000
F30.2 Mania with psychotic symptoms	0.004	0.996	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.004	0.996	0.000
N21 Calculus of lower urinary tract	0.004	0.996	0.000
D41.9 Urinary organ, unspecified	0.003	0.996	0.000
D41.7 Other urinary organs	0.003	0.996	0.000
D41.3 Urethra	0.003	0.996	0.000
D41.2 Ureter	0.003	0.996	0.000
D41.1 Renal pelvis	0.003	0.996	0.000
F10.3 Withdrawal state	0.000	0.996	0.004
K50.9 Crohn's disease, unspecified	0.004	0.996	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.996	0.003
F38.8 Other specified mood [affective] disorders	0.003	0.996	0.000
F38.1 Other recurrent mood [affective] disorders	0.003	0.996	0.000
F38.0 Other single mood [affective] disorders	0.003	0.996	0.000
J18 Pneumonia, organism unspecified	0.004	0.996	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.996	0.004
E66 Obesity	0.003	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.997	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.997	0.000
F34.0 Cyclothymia	0.003	0.997	0.000
R06.2 Wheezing	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
F34.1 Dysthymia	0.003	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
K13.7 Other and unspecified lesions of oral mucosa	0.003	0.997	0.000
I67.2 Cerebral atherosclerosis	0.003	0.997	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.003	0.997	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.003	0.997	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.003	0.997	0.000
N21.8 Other lower urinary tract calculus	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.997	0.001
E66.0 Obesity due to excess calories	0.003	0.997	0.000
D41.0 Kidney	0.003	0.997	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.997	0.003
F11 Mental and behavioural disorders due to use of opioids	0.000	0.997	0.003
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.997	0.002
F18 Mental and behavioural disorders due to use of volatile solvents	0.000	0.997	0.002
F16 Mental and behavioural disorders due to use of hallucinogens	0.000	0.997	0.002
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.000	0.997	0.002
F14 Mental and behavioural disorders due to use of cocaine	0.000	0.997	0.002
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.000	0.997	0.002
F17.2 Dependence syndrome	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.003	0.997	0.000
J18.8 Other pneumonia, organism unspecified	0.003	0.997	0.000
J18.2 Hypostatic pneumonia, unspecified	0.003	0.997	0.000
H91 Other hearing loss	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.003	0.997	0.000
E66.1 Drug-induced obesity	0.003	0.997	0.000
N21.1 Calculus in urethra	0.003	0.997	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.003	0.997	0.000
L29.2 Pruritus vulvae	0.003	0.997	0.000
D24 Benign neoplasm of breast	0.000	0.997	0.003
H91.8 Other specified hearing loss	0.003	0.997	0.000
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.003	0.997	0.000
R73 Elevated blood glucose level	0.002	0.997	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
F12.1 Harmful use	0.000	0.998	0.002
N83.2 Other and unspecified ovarian cysts	0.000	0.998	0.002
H01.0 Blepharitis	0.000	0.998	0.002
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
F11.2 Dependence syndrome	0.000	0.998	0.002
F12.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F12.8 Other mental and behavioural disorders	0.000	0.998	0.002
F12.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F12.6 Amnesic syndrome	0.000	0.998	0.002
F12.5 Psychotic disorder	0.000	0.998	0.002
F12.4 Withdrawal state with delirium	0.000	0.998	0.002
F12.3 Withdrawal state	0.000	0.998	0.002
F12.2 Dependence syndrome	0.000	0.998	0.002
F12.0 Acute intoxication	0.000	0.998	0.002
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
F11.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F11.8 Other mental and behavioural disorders	0.000	0.998	0.002
F11.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F11.6 Amnesic syndrome	0.000	0.998	0.002
F11.5 Psychotic disorder	0.000	0.998	0.002
F11.4 Withdrawal state with delirium	0.000	0.998	0.002
F11.3 Withdrawal state	0.000	0.998	0.002
F11.1 Harmful use	0.000	0.998	0.002
F11.0 Acute intoxication	0.000	0.998	0.002
F13.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F13.8 Other mental and behavioural disorders	0.000	0.998	0.002
F13.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F13.6 Amnesic syndrome	0.000	0.998	0.002
F13.5 Psychotic disorder	0.000	0.998	0.002
F13.4 Withdrawal state with delirium	0.000	0.998	0.002
F13.3 Withdrawal state	0.000	0.998	0.002
F13.2 Dependence syndrome	0.000	0.998	0.002
F13.1 Harmful use	0.000	0.998	0.002
F13.0 Acute intoxication	0.000	0.998	0.002
F14.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F14.8 Other mental and behavioural disorders	0.000	0.998	0.002
F14.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F14.6 Amnesic syndrome	0.000	0.998	0.002
F14.5 Psychotic disorder	0.000	0.998	0.002
F14.4 Withdrawal state with delirium	0.000	0.998	0.002
F14.3 Withdrawal state	0.000	0.998	0.002
F14.2 Dependence syndrome	0.000	0.998	0.002
F14.1 Harmful use	0.000	0.998	0.002
F14.0 Acute intoxication	0.000	0.998	0.002
F15.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F15.8 Other mental and behavioural disorders	0.000	0.998	0.002
F15.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F15.6 Amnesic syndrome	0.000	0.998	0.002
F15.5 Psychotic disorder	0.000	0.998	0.002
F15.4 Withdrawal state with delirium	0.000	0.998	0.002
F15.3 Withdrawal state	0.000	0.998	0.002
F15.2 Dependence syndrome	0.000	0.998	0.002
F15.1 Harmful use	0.000	0.998	0.002
F15.0 Acute intoxication	0.000	0.998	0.002
F16.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F16.8 Other mental and behavioural disorders	0.000	0.998	0.002
F16.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F16.6 Amnesic syndrome	0.000	0.998	0.002
F16.5 Psychotic disorder	0.000	0.998	0.002
F16.4 Withdrawal state with delirium	0.000	0.998	0.002
F16.3 Withdrawal state	0.000	0.998	0.002
F16.2 Dependence syndrome	0.000	0.998	0.002
F16.1 Harmful use	0.000	0.998	0.002
F16.0 Acute intoxication	0.000	0.998	0.002
F18.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F18.8 Other mental and behavioural disorders	0.000	0.998	0.002
F18.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F18.6 Amnesic syndrome	0.000	0.998	0.002
F18.5 Psychotic disorder	0.000	0.998	0.002
F18.4 Withdrawal state with delirium	0.000	0.998	0.002
F18.3 Withdrawal state	0.000	0.998	0.002
F18.2 Dependence syndrome	0.000	0.998	0.002
F18.1 Harmful use	0.000	0.998	0.002
F18.0 Acute intoxication	0.000	0.998	0.002
F19.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F19.8 Other mental and behavioural disorders	0.000	0.998	0.002
F19.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F19.6 Amnesic syndrome	0.000	0.998	0.002
F19.5 Psychotic disorder	0.000	0.998	0.002
F19.4 Withdrawal state with delirium	0.000	0.998	0.002
F19.3 Withdrawal state	0.000	0.998	0.002
F19.2 Dependence syndrome	0.000	0.998	0.002
F19.1 Harmful use	0.000	0.998	0.002
F19.0 Acute intoxication	0.000	0.998	0.002
M65.34 Trigger finger-Hand	0.002	0.998	0.000
I50.0 Congestive heart failure	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
I67.9 Cerebrovascular disease, unspecified	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
Z45.2 Adjustment and management of vascular access device	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
R06.6 Hiccough	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
D12.5 Sigmoid colon	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
H18.4 Corneal degeneration	0.000	0.998	0.002
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
C34 Malignant neoplasm of bronchus and lung	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
C34.2 Middle lobe, bronchus or lung	0.002	0.998	0.000
I50 Heart failure	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
I67 Other cerebrovascular diseases	0.002	0.998	0.000
R74 Abnormal serum enzyme levels	0.002	0.998	0.000
R02 Gangrene, not elsewhere classified	0.000	0.998	0.002
Y83.4 Other reconstructive surgery	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
J22 Unspecified acute lower respiratory infection	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
C34.0 Main bronchus	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
R59.9 Enlarged lymph nodes, unspecified	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
L29 Pruritus	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
R06 Abnormalities of breathing	0.002	0.998	0.000
C34.8 Overlapping lesion of bronchus and lung	0.002	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.998	0.002
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
C78.0 Secondary malignant neoplasm of lung	0.002	0.998	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.998	0.000
I67.5 Moyamoya disease	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.998	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.002	0.998	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.002	0.998	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.001	0.998	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.002	0.998	0.000
D41.4 Bladder	0.001	0.998	0.001
D68.6 Other Thrombophilia	0.002	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.002	0.998	0.000
Z35.6 Supervision of very young primigravida	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations