TreeWAS – Variant ID: rs10858946

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H52.0 Hypermetropia	0.215	0.785	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.197	0.803	0.000
I10 Essential (primary) hypertension	0.190	0.810	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.178	0.822	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.166	0.834	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.158	0.842	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.155	0.845	0.000
T42.0 Hydantoin derivatives	0.151	0.849	0.000
T39.0 Salicylates	0.151	0.849	0.000
T39.1 4-Aminophenol derivatives	0.147	0.853	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.143	0.857	0.000
T46.1 Calcium-channel blockers	0.141	0.859	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.140	0.859	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.136	0.864	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.133	0.867	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.132	0.868	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.131	0.869	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.128	0.872	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.128	0.872	0.000
T42.3 Barbiturates	0.128	0.872	0.000
T42.2 Succinimides and oxazolidinediones	0.128	0.872	0.000
T40.2 Other opioids	0.126	0.874	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.125	0.875	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.125	0.875	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.125	0.875	0.000
T36 Poisoning by systemic antibiotics	0.124	0.876	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.121	0.879	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.119	0.881	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.119	0.881	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.113	0.887	0.000
T46.7 Peripheral vasodilators	0.113	0.887	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.113	0.887	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.113	0.887	0.000
T40.4 Other synthetic narcotics	0.112	0.888	0.000
T39.4 Antirheumatics, not elsewhere classified	0.111	0.889	0.000
T39.2 Pyrazolone derivatives	0.111	0.889	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.111	0.889	0.000
T48.5 Anti-common-cold drugs	0.110	0.890	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.109	0.890	0.000
T42.4 Benzodiazepines	0.109	0.891	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.107	0.893	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.106	0.894	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.105	0.895	0.000
T47.4 Other laxatives	0.104	0.896	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.103	0.897	0.000
T40.8 Lysergide [LSD]	0.103	0.897	0.000
T40.7 Cannabis (derivatives)	0.103	0.897	0.000
T40.5 Cocaine	0.103	0.897	0.000
T40.3 Methadone	0.103	0.897	0.000
T40.1 Heroin	0.103	0.897	0.000
T40.0 Opium	0.103	0.897	0.000
T42.1 Iminostilbenes	0.101	0.898	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.101	0.899	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.101	0.899	0.000
T47.7 Emetics	0.101	0.899	0.000
T47.6 Antidiarrhoeal drugs	0.101	0.899	0.000
T47.5 Digestants	0.101	0.899	0.000
T47.3 Saline and osmotic laxatives	0.101	0.899	0.000
T47.2 Stimulant laxatives	0.101	0.899	0.000
T47.0 Histamine H(2)-receptor antagonists	0.101	0.899	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.100	0.900	0.000
N41.1 Chronic prostatitis	0.099	0.901	0.000
T36.8 Other systemic antibiotics	0.098	0.902	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.098	0.902	0.000
T48.4 Expectorants	0.098	0.902	0.000
T48.3 Antitussives	0.098	0.902	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.098	0.902	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.098	0.902	0.000
T48.0 Oxytocic drugs	0.098	0.902	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.096	0.904	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.095	0.905	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.095	0.905	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.095	0.905	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.095	0.905	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.095	0.905	0.000
T44.0 Anticholinesterase agents	0.095	0.905	0.000
N41 Inflammatory diseases of prostate	0.094	0.906	0.000
T40.6 Other and unspecified narcotics	0.092	0.907	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.091	0.909	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.091	0.909	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.090	0.910	0.000
T37.5 Antiviral drugs	0.090	0.910	0.000
T37.4 Anthelminthics	0.090	0.910	0.000
T37.3 Other antiprotozoal drugs	0.090	0.910	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.090	0.910	0.000
T37.1 Antimycobacterial drugs	0.090	0.910	0.000
T37.0 Sulphonamides	0.090	0.910	0.000
T36.9 Systemic antibiotic, unspecified	0.089	0.911	0.000
T36.7 Antifungal antibiotics, systemically used	0.089	0.911	0.000
T36.6 Rifamycins	0.089	0.911	0.000
T36.5 Aminoglycosides	0.089	0.911	0.000
T36.4 Tetracyclines	0.089	0.911	0.000
T36.2 Chloramphenicol group	0.089	0.911	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.089	0.911	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.089	0.911	0.000
T36.3 Macrolides	0.088	0.912	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.087	0.912	0.000
N41.0 Acute prostatitis	0.087	0.913	0.000
T41.5 Therapeutic gases	0.086	0.914	0.000
T41.4 Anaesthetic, unspecified	0.086	0.914	0.000
T41.3 Local anaesthetics	0.086	0.914	0.000
T41.2 Other and unspecified general anaesthetics	0.086	0.914	0.000
T41.1 Intravenous anaesthetics	0.086	0.914	0.000
T41.0 Inhaled anaesthetics	0.086	0.914	0.000
T49.9 Topical agent, unspecified	0.086	0.914	0.000
T49.8 Other topical agents	0.086	0.914	0.000
T49.7 Dental drugs, topically applied	0.086	0.914	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.086	0.914	0.000
T49.5 Ophthalmological drugs and preparations	0.086	0.914	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.086	0.914	0.000
T49.3 Emollients, demulcents and protectants	0.086	0.914	0.000
T49.2 Local astringents and local detergents	0.086	0.914	0.000
T49.1 Antipruritics	0.086	0.914	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.086	0.914	0.000
T36.0 Penicillins	0.085	0.915	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.084	0.916	0.000
N41.2 Abscess of prostate	0.076	0.924	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.071	0.929	0.000
N41.3 Prostatocystitis	0.068	0.932	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.067	0.932	0.000
N41.8 Other inflammatory diseases of prostate	0.066	0.933	0.000
T45.2 Vitamins, not elsewhere classified	0.066	0.934	0.000
I10-I15 Hypertensive diseases	0.066	0.934	0.000
T38.9 Other and unspecified hormone antagonists	0.066	0.934	0.000
T38.7 Androgens and anabolic congeners	0.066	0.934	0.000
T38.5 Other oestrogens and progestogens	0.066	0.934	0.000
T38.4 Oral contraceptives	0.066	0.934	0.000
T38.2 Antithyroid drugs	0.066	0.934	0.000
T38.0 Glucocorticoids and synthetic analogues	0.066	0.934	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.065	0.934	0.000
T45.8 Other primarily systemic and haematological agents	0.065	0.934	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.065	0.934	0.000
T45.6 Fibrinolysis-affecting drugs	0.065	0.934	0.000
T45.4 Iron and its compounds	0.065	0.934	0.000
T45.3 Enzymes, not elsewhere classified	0.065	0.934	0.000
T50.4 Drugs affecting uric acid metabolism	0.063	0.937	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.063	0.937	0.000
I11 Hypertensive heart disease	0.062	0.938	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.062	0.938	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.061	0.939	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.061	0.939	0.000
T45.5 Anticoagulants	0.061	0.939	0.000
T50.7 Analeptics and opioid receptor antagonists	0.060	0.939	0.000
T50.5 Appetite depressants	0.060	0.939	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.060	0.939	0.000
T50.1 Loop [high-ceiling] diuretics	0.060	0.939	0.000
T50.0 Mineralocorticoids and their antagonists	0.060	0.939	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.061	0.939	0.000
T45.0 Antiallergic and antiemetic drugs	0.060	0.940	0.000
T50.8 Diagnostic agents	0.058	0.942	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.057	0.943	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.053	0.947	0.000
T38.1 Thyroid hormones and substitutes	0.049	0.950	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.048	0.952	0.000
I13 Hypertensive heart and renal disease	0.048	0.952	0.000
T43.6 Psychostimulants with abuse potential	0.037	0.963	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.037	0.963	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.036	0.964	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.035	0.965	0.000
T43.9 Psychotropic drug, unspecified	0.034	0.965	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.034	0.965	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.034	0.966	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.034	0.966	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.034	0.966	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.034	0.966	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.033	0.967	0.000
T43.2 Other and unspecified antidepressants	0.032	0.968	0.000
H52 Disorders of refraction and accommodation	0.028	0.972	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.026	0.974	0.000
I15 Secondary hypertension	0.025	0.974	0.001
T43.0 Tricyclic and tetracyclic antidepressants	0.025	0.975	0.000
I12 Hypertensive renal disease	0.023	0.977	0.000
H52.7 Disorder of refraction, unspecified	0.021	0.979	0.000
H52.6 Other disorders of refraction	0.020	0.980	0.000
H52.5 Disorders of accommodation	0.020	0.980	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.981	0.019
H52.4 Presbyopia	0.019	0.981	0.000
I15.8 Other secondary hypertension	0.018	0.981	0.001
I15.2 Hypertension secondary to endocrine disorders	0.018	0.981	0.001
H52.2 Astigmatism	0.019	0.981	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.982	0.018
H66 Suppurative and unspecified otitis media	0.000	0.982	0.018
T43.3 Phenothiazine antipsychotics and neuroleptics	0.017	0.983	0.000
H72 Perforation of tympanic membrane	0.000	0.983	0.017
I15.0 Renovascular hypertension	0.016	0.983	0.001
T50.9 Other and unspecified drugs, medicaments and biological substances	0.016	0.984	0.001
H66.4 Suppurative otitis media, unspecified	0.000	0.984	0.016
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.985	0.015
H65-H75 Diseases of middle ear and mastoid	0.000	0.985	0.015
I15.9 Seconday hypertension, unspecified	0.015	0.985	0.001
H52.3 Anisometropia and aniseikonia	0.015	0.985	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.985	0.015
H72.1 Attic perforation of tympanic membrane	0.000	0.986	0.014
H72.8 Other perforations of tympanic membrane	0.000	0.986	0.014
H66.0 Acute suppurative otitis media	0.000	0.986	0.013
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.987	0.013
J34.3 Hypertrophy of nasal turbinates	0.000	0.987	0.013
H70 Mastoiditis and related conditions	0.000	0.987	0.013
H71 Cholesteatoma of middle ear	0.000	0.988	0.012
H74 Other disorders of middle ear and mastoid	0.000	0.988	0.012
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.988	0.012
I12.9 Hypertensive renal disease without renal failure	0.012	0.988	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.989	0.011
H68 Eustachian salpingitis and obstruction	0.000	0.989	0.011
H67 Otitis media in diseases classified elsewhere	0.000	0.989	0.011
H70.9 Mastoiditis, unspecified	0.000	0.989	0.011
H69 Other disorders of Eustachian tube	0.000	0.989	0.011
H26.4 After-cataract	0.010	0.990	0.000
I15.1 Hypertension secondary to other renal disorders	0.009	0.990	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.990	0.010
H70.1 Chronic mastoiditis	0.000	0.990	0.010
Z90.2 Acquired absence of lung [part of]	0.000	0.990	0.010
H74.0 Tympanosclerosis	0.000	0.991	0.009
H70.2 Petrositis	0.000	0.991	0.009
H70.0 Acute mastoiditis	0.000	0.991	0.009
H69.8 Other specified disorders of Eustachian tube	0.000	0.991	0.009
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.992	0.008
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.992	0.008
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.992	0.008
H68.1 Obstruction of Eustachian tube	0.000	0.992	0.008
H68.0 Eustachian salpingitis	0.000	0.992	0.008
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.992	0.008
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
H26 Other cataract	0.008	0.992	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.992	0.008
H26.2 Complicated cataract	0.008	0.992	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.992	0.008
H73 Other disorders of tympanic membrane	0.000	0.992	0.008
H69.0 Patulous Eustachian tube	0.000	0.992	0.008
H80.9 Otosclerosis, unspecified	0.000	0.992	0.008
H74.1 Adhesive middle ear disease	0.000	0.992	0.008
Chapter VIII Diseases of the ear and mastoid process	0.000	0.992	0.008
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.992	0.007
H26.9 Cataract, unspecified	0.007	0.993	0.000
H80 Otosclerosis	0.000	0.993	0.007
H61.8 Other specified disorders of external ear	0.000	0.993	0.007
H66.9 Otitis media, unspecified	0.000	0.993	0.007
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.993	0.007
H80-H83 Diseases of inner ear	0.000	0.993	0.007
H26.1 Traumatic cataract	0.007	0.993	0.000
H81.0 Meniere's disease	0.000	0.993	0.007
H61 Other disorders of external ear	0.000	0.994	0.006
H74.4 Polyp of middle ear	0.000	0.994	0.006
H52.1 Myopia	0.006	0.994	0.000
H60-H62 Diseases of external ear	0.000	0.994	0.006
H26.3 Drug-induced cataract	0.006	0.994	0.000
H73.1 Chronic myringitis	0.000	0.994	0.006
H73.0 Acute myringitis	0.000	0.994	0.006
M25.76 Osteophyte (Lower leg)	0.000	0.994	0.006
I12.0 Hypertensive renal disease with renal failure	0.006	0.994	0.000
H26.0 Infantile, juvenile and presenile cataract	0.006	0.994	0.000
H61.0 Perichondritis of external ear	0.000	0.994	0.006
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.994	0.005
H69.9 Eustachian tube disorder, unspecified	0.000	0.995	0.005
H80.8 Other otosclerosis	0.000	0.995	0.005
H80.2 Cochlear otosclerosis	0.000	0.995	0.005
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.995	0.005
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.995	0.005
H81 Disorders of vestibular function	0.000	0.995	0.005
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.005	0.995	0.000
R59.9 Enlarged lymph nodes, unspecified	0.005	0.995	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.995	0.005
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.995	0.005
H26.8 Other specified cataract	0.005	0.995	0.000
N28.1 Cyst of kidney, acquired	0.000	0.995	0.005
H61.9 Disorder of external ear, unspecified	0.000	0.995	0.005
H61.1 Non-infective disorders of pinna	0.000	0.995	0.005
H61.3 Acquired stenosis of external ear canal	0.000	0.995	0.005
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.995	0.004
H81.4 Vertigo of central origin	0.000	0.996	0.004
H51 Other disorders of binocular movement	0.004	0.996	0.000
H81.2 Vestibular neuronitis	0.000	0.996	0.004
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.996	0.004
R40.0 Somnolence	0.000	0.996	0.004
H81.3 Other peripheral vertigo	0.000	0.996	0.004
H81.8 Other disorders of vestibular function	0.000	0.996	0.003
L29.9 Pruritus, unspecified	0.000	0.996	0.004
H49 Paralytic strabismus	0.004	0.996	0.000
L90.5 Scar conditions and fibrosis of skin	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.996	0.004
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.996	0.004
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.996	0.003
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.996	0.003
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
H62.2 Otitis externa in mycoses	0.000	0.996	0.003
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.996	0.003
S82.30 Fracture of lower end of tibia (closed)	0.004	0.996	0.000
H61.2 Impacted cerumen	0.000	0.996	0.004
L29.0 Pruritus ani	0.000	0.996	0.004
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.997	0.003
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.997	0.003
L29.2 Pruritus vulvae	0.000	0.997	0.003
L29 Pruritus	0.000	0.997	0.003
H49.8 Other paralytic strabismus	0.003	0.997	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.003	0.997	0.000
S89.8 Other specified injuries of lower leg	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
H51.9 Disorder of binocular movement, unspecified	0.003	0.997	0.000
H51.8 Other specified disorders of binocular movement	0.003	0.997	0.000
H51.1 Convergence insufficiency and excess	0.003	0.997	0.000
H51.0 Palsy of conjugate gaze	0.003	0.997	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.997	0.003
M24.1 Other articular cartilage disorders	0.000	0.997	0.003
D36.7 Other specified sites	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.003	0.997	0.000
H51.2 Internuclear ophthalmoplegia	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
H81.9 Disorder of vestibular function, unspecified	0.000	0.997	0.003
D63.0 Anaemia in neoplastic disease	0.000	0.997	0.003
L29.8 Other pruritus	0.000	0.997	0.003
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
H49.4 Progressive external ophthalmoplegia	0.003	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
M07.3 Other psoriatic arthropathies	0.003	0.997	0.000
M50.3 Other cervical disk degeneration	0.000	0.997	0.003
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.997	0.003
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.997	0.003
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.997	0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
H60 Otitis externa	0.000	0.997	0.003
L29.1 Pruritus scroti	0.000	0.997	0.003
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.997	0.003
R03.1 Nonspecific low blood-pressure reading	0.000	0.997	0.003
Z63.0 Problems in relationship with spouse or partner	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.997	0.003
C61 Malignant neoplasm of prostate	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.997	0.002
M24.18 Other articular cartilage disorders (Other)	0.000	0.997	0.002
M24.14 Other articular cartilage disorders (Hand)	0.000	0.997	0.002
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.997	0.002
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.997	0.002
L29.3 Anogenital pruritus, unspecified	0.000	0.997	0.002
H90 Conductive and sensorineural hearing loss	0.000	0.997	0.003
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.997	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.997	0.002
O82.0 Delivery by elective Caesarean section	0.002	0.997	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
S89 Other and unspecified injuries of lower leg	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
H60.3 Other infective otitis externa	0.000	0.998	0.002
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
H25-H28 Disorders of lens	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
H83 Other diseases of inner ear	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
H91.8 Other specified hearing loss	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
H60.0 Abscess of external ear	0.000	0.998	0.002
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
B07 Viral warts	0.000	0.998	0.002
H90.3 Sensorineural hearing loss, bilateral	0.000	0.998	0.002
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
B35.1 Tinea unguium	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.000	0.998	0.002
H92.2 Otorrhagia	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.000	0.998	0.002
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.000	0.998	0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
H91 Other hearing loss	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.000	0.998	0.002
H83.2 Labyrinthine dysfunction	0.000	0.998	0.002
H83.1 Labyrinthine fistula	0.000	0.998	0.002
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
H60.4 Cholesteatoma of external ear	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.002	0.998	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.002	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.998	0.002
H83.3 Noise effects on inner ear	0.000	0.998	0.002
H60.8 Other otitis externa	0.000	0.998	0.002
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.000	0.998	0.002
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
C60.1 Glans penis	0.002	0.998	0.000
H27 Other disorders of lens	0.002	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.000	0.998	0.001
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
C60 Malignant neoplasm of penis	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.000	0.998	0.002
F17.2 Dependence syndrome	0.000	0.998	0.002
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.001	0.998	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.001	0.998	0.000
H28.2 Cataract in other diseases classified elsewhere	0.001	0.998	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.001	0.998	0.000
J93.8 Other pneumothorax	0.000	0.998	0.002
K22.8 Other specified diseases of oesophagus	0.000	0.998	0.002
H91.1 Presbycusis	0.000	0.998	0.002
R40.1 Stupor	0.000	0.998	0.002
X41.9 Unspecified place	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
C60.9 Penis, unspecified	0.002	0.998	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.000	0.998	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
H91.0 Ototoxic hearing loss	0.000	0.998	0.001
S82.11 Fracture of upper end of tibia (open)	0.001	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.001	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.001	0.998	0.000
B35.9 Dermatophytosis, unspecified	0.002	0.998	0.000
H27.0 Aphakia	0.002	0.998	0.000
K81.1 Chronic cholecystitis	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
H28.0 Diabetic cataract	0.001	0.998	0.000
H35.7 Separation of retinal layers	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.000	0.998	0.001
B35 Dermatophytosis	0.002	0.998	0.000
D36 Benign neoplasm of other and unspecified sites	0.000	0.998	0.001
S82.86 Maisonneuve's fracture	0.001	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
H33.2 Serous retinal detachment	0.002	0.998	0.000
C60.0 Prepuce	0.001	0.998	0.000
H27.9 Disorder of lens, unspecified	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.001
K76.9 Liver disease, unspecified	0.000	0.998	0.002
T51.0 Ethanol	0.002	0.998	0.000
B35.3 Tinea pedis	0.001	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.000	0.998	0.001
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.001	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.999	0.001
S82.61 Fracture of lateral malleolus (open)	0.001	0.999	0.000
C60.8 Overlapping lesion of penis	0.001	0.999	0.000
C60.2 Body of penis	0.001	0.999	0.000
V80.9 Rider or occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
R73 Elevated blood glucose level	0.001	0.999	0.000
H33.0 Retinal detachment with retinal break	0.001	0.999	0.000
H65 Nonsuppurative otitis media	0.000	0.999	0.001
M24.02 Loose body in joint (Upper arm)	0.000	0.999	0.001
S82.70 Multiple fractures of lower leg (closed)	0.001	0.999	0.000
B35.4 Tinea corporis	0.001	0.999	0.000
T51.9 Alcohol, unspecified	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.999	0.001
B35.6 Tinea cruris	0.001	0.999	0.000
C60-C63 Malignant neoplasms of male genital organs	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.999	0.001
B35.8 Other dermatophytoses	0.001	0.999	0.000
B35.5 Tinea imbricata	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations