TreeWAS – Variant ID: rs10888838

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.806	0.194
D27 Benign neoplasm of ovary	0.000	0.969	0.031
M25.47 Effusion of joint (Ankle and foot)	0.022	0.978	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.019	0.981	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.017	0.983	0.000
T42.4 Benzodiazepines	0.014	0.986	0.000
T42.0 Hydantoin derivatives	0.014	0.986	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.013	0.987	0.000
G44.2 Tension-type headache	0.000	0.987	0.013
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.012	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.012	0.988	0.000
T42.3 Barbiturates	0.012	0.988	0.000
T42.2 Succinimides and oxazolidinediones	0.012	0.988	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.012	0.988	0.000
T42.1 Iminostilbenes	0.012	0.988	0.000
O75.8 Other specified complications of labour and delivery	0.012	0.988	0.000
O62.2 Other uterine inertia	0.012	0.988	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.012	0.988	0.000
O62 Abnormalities of forces of labour	0.012	0.988	0.000
T40.2 Other opioids	0.012	0.988	0.000
O36.6 Maternal care for excessive foetal growth	0.011	0.989	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.011	0.989	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.011	0.989	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.011	0.989	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.989	0.011
O36 Maternal care for other known or suspected foetal problems	0.011	0.989	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.010	0.989	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.010	0.990	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990	0.000
O60-O75 Complications of labour and delivery	0.010	0.990	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
O75.0 Maternal distress during labour and delivery	0.010	0.990	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.010	0.990	0.000
O36.5 Maternal care for poor foetal growth	0.010	0.990	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.990	0.010
O62.3 Precipitate labour	0.010	0.990	0.000
T36 Poisoning by systemic antibiotics	0.009	0.990	0.000
O02.1 Missed abortion	0.009	0.991	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.009	0.991	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.009	0.991	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.009	0.991	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.009	0.991	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.009	0.991	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.009	0.991	0.000
S62.60 Fracture of other finger (closed)	0.009	0.991	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.991	0.009
T47.0 Histamine H(2)-receptor antagonists	0.009	0.991	0.000
T48.5 Anti-common-cold drugs	0.009	0.991	0.000
T40.4 Other synthetic narcotics	0.009	0.991	0.000
G44 Other headache syndromes	0.000	0.991	0.009
O63.1 Prolonged second stage (of labour)	0.009	0.991	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.008	0.991	0.000
T40.8 Lysergide [LSD]	0.008	0.991	0.000
T40.7 Cannabis (derivatives)	0.008	0.991	0.000
T40.5 Cocaine	0.008	0.991	0.000
T40.3 Methadone	0.008	0.991	0.000
T40.1 Heroin	0.008	0.991	0.000
T40.0 Opium	0.008	0.991	0.000
O62.9 Abnormality of forces of labour, unspecified	0.008	0.991	0.000
O62.8 Other abnormalities of forces of labour	0.008	0.991	0.000
T45.5 Anticoagulants	0.008	0.991	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.008	0.992	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.008	0.992	0.000
O75.9 Complication of labour and delivery, unspecified	0.008	0.992	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.008	0.992	0.000
O75.4 Other complications of obstetric surgery and procedures	0.008	0.992	0.000
O75.3 Other infection during labour	0.008	0.992	0.000
O75.1 Shock during or following labour and delivery	0.008	0.992	0.000
O36.4 Maternal care for intra-uterine death	0.008	0.992	0.000
O62.1 Secondary uterine inertia	0.008	0.992	0.000
O71 Other obstetric trauma	0.008	0.992	0.000
O63 Long labour	0.008	0.992	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.992	0.008
O73 Retained placenta and membranes, without haemorrhage	0.008	0.992	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.008	0.992	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.008	0.992	0.000
O61 Failed induction of labour	0.008	0.992	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.992	0.008
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.992	0.008
O65 Obstructed labour due to maternal pelvic abnormality	0.008	0.992	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.992	0.008
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.008	0.992	0.000
O36.2 Maternal care for hydrops foetalis	0.008	0.992	0.000
O36.1 Maternal care for other isoimmunisation	0.008	0.992	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.008	0.992	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.008	0.992	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
T47.7 Emetics	0.008	0.992	0.000
T47.6 Antidiarrhoeal drugs	0.008	0.992	0.000
T47.5 Digestants	0.008	0.992	0.000
T47.4 Other laxatives	0.008	0.992	0.000
T47.3 Saline and osmotic laxatives	0.008	0.992	0.000
T47.2 Stimulant laxatives	0.008	0.992	0.000
O02 Other abnormal products of conception	0.008	0.992	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O66 Other obstructed labour	0.008	0.992	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.008	0.992	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.992	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.992	0.000
T48.4 Expectorants	0.007	0.992	0.000
T48.3 Antitussives	0.007	0.992	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.992	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.992	0.000
T48.0 Oxytocic drugs	0.007	0.992	0.000
O74 Complications of anaesthesia during labour and delivery	0.007	0.992	0.000
O60 Preterm delivery	0.007	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.992	0.000
T38.7 Androgens and anabolic congeners	0.007	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.992	0.000
T38.5 Other oestrogens and progestogens	0.007	0.992	0.000
T38.4 Oral contraceptives	0.007	0.992	0.000
T38.2 Antithyroid drugs	0.007	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.992	0.000
T36.0 Penicillins	0.007	0.992	0.000
G44.8 Other specified headache syndromes	0.000	0.992	0.007
O00-O08 Pregnancy with abortive outcome	0.007	0.992	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.993	0.007
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.993	0.007
T45.9 Primarily systemic and haematological agent, unspecified	0.007	0.993	0.000
T45.8 Other primarily systemic and haematological agents	0.007	0.993	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
T45.6 Fibrinolysis-affecting drugs	0.007	0.993	0.000
T45.4 Iron and its compounds	0.007	0.993	0.000
T45.3 Enzymes, not elsewhere classified	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.007	0.993	0.000
G44.0 Cluster headache syndrome	0.000	0.993	0.007
T36.9 Systemic antibiotic, unspecified	0.007	0.993	0.000
T36.8 Other systemic antibiotics	0.007	0.993	0.000
T36.7 Antifungal antibiotics, systemically used	0.007	0.993	0.000
T36.6 Rifamycins	0.007	0.993	0.000
T36.5 Aminoglycosides	0.007	0.993	0.000
T36.4 Tetracyclines	0.007	0.993	0.000
T36.3 Macrolides	0.007	0.993	0.000
T36.2 Chloramphenicol group	0.007	0.993	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
O71.4 Obstetric high vaginal laceration alone	0.007	0.993	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.007	0.993	0.000
O69.8 Labour and delivery complicated by other cord complications	0.007	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.993	0.007
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.007	0.993	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.993	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.993	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.993	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.993	0.000
T44.0 Anticholinesterase agents	0.007	0.993	0.000
O71.9 Obstetric trauma, unspecified	0.007	0.993	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.993	0.007
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.007	0.993	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.007	0.993	0.000
T37.5 Antiviral drugs	0.007	0.993	0.000
T37.4 Anthelminthics	0.007	0.993	0.000
T37.3 Other antiprotozoal drugs	0.007	0.993	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.007	0.993	0.000
T37.1 Antimycobacterial drugs	0.007	0.993	0.000
T37.0 Sulphonamides	0.007	0.993	0.000
T41.5 Therapeutic gases	0.007	0.993	0.000
T41.4 Anaesthetic, unspecified	0.007	0.993	0.000
T41.3 Local anaesthetics	0.007	0.993	0.000
T41.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
T41.1 Intravenous anaesthetics	0.007	0.993	0.000
T41.0 Inhaled anaesthetics	0.007	0.993	0.000
T49.9 Topical agent, unspecified	0.007	0.993	0.000
T49.8 Other topical agents	0.007	0.993	0.000
T49.7 Dental drugs, topically applied	0.007	0.993	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.007	0.993	0.000
T49.5 Ophthalmological drugs and preparations	0.007	0.993	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.993	0.000
T49.3 Emollients, demulcents and protectants	0.007	0.993	0.000
T49.2 Local astringents and local detergents	0.007	0.993	0.000
T49.1 Antipruritics	0.007	0.993	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
T46.7 Peripheral vasodilators	0.007	0.993	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.007	0.993	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
J43.9 Emphysema, unspecified	0.007	0.993	0.000
O62.0 Primary inadequate contractions	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
B95-B98 Bacterial, viral and other infectious agents	0.000	0.993	0.007
S62.6 Fracture of other finger	0.007	0.993	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.007	0.993	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.007	0.993	0.000
O69.3 Labour and delivery complicated by short cord	0.007	0.993	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.007	0.993	0.000
O16 Unspecified maternal hypertension	0.007	0.993	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.993	0.007
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.007	0.993	0.000
S62.61 Fracture of other finger (open)	0.007	0.993	0.000
G44.3 Chronic posttraumatic headache	0.000	0.993	0.006
O36.9 Maternal care for foetal problem, unspecified	0.006	0.994	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.006	0.994	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.994	0.006
O03 Spontaneous abortion	0.006	0.994	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O67.8 Other intrapartum haemorrhage	0.006	0.994	0.000
O61.0 Failed medical induction of labour	0.006	0.994	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.006	0.994	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.006	0.994	0.000
O73.0 Retained placenta, without haemorrhage	0.006	0.994	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.006	0.994	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.006	0.994	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.006	0.994	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.006	0.994	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.006	0.994	0.000
O71.7 Obstetric haematoma of pelvis	0.006	0.994	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.006	0.994	0.000
O71.5 Other obstetric injury to pelvic organs	0.006	0.994	0.000
O71.3 Obstetric laceration of cervix	0.006	0.994	0.000
O71.2 Postpartum inversion of uterus	0.006	0.994	0.000
O71.1 Rupture of uterus during labour	0.006	0.994	0.000
O71.0 Rupture of uterus before onset of labour	0.006	0.994	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.006	0.994	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.006	0.994	0.000
O72 Postpartum haemorrhage	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
O61.9 Failed induction of labour, unspecified	0.006	0.994	0.000
O61.8 Other failed induction of labour	0.006	0.994	0.000
O61.1 Failed instrumental induction of labour	0.006	0.994	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.006	0.994	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.006	0.994	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.006	0.994	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.006	0.994	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.006	0.994	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.006	0.994	0.000
O65.0 Obstructed labour due to deformed pelvis	0.006	0.994	0.000
G44.1 Vascular headache, not elsewhere classified	0.000	0.994	0.006
O15 Eclampsia	0.006	0.994	0.000
O02.9 Abnormal product of conception, unspecified	0.006	0.994	0.000
O02.8 Other specified abnormal products of conception	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.006	0.994	0.000
O66.9 Obstructed labour, unspecified	0.006	0.994	0.000
O66.8 Other specified obstructed labour	0.006	0.994	0.000
O66.4 Failed trial of labour, unspecified	0.006	0.994	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.006	0.994	0.000
O66.2 Obstructed labour due to unusually large foetus	0.006	0.994	0.000
O66.1 Obstructed labour due to locked twins	0.006	0.994	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.006	0.994	0.000
T39.0 Salicylates	0.006	0.994	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.994	0.006
O60.3 Preterm delivery without spontaneous labour	0.005	0.994	0.000
O60.2 Preterm spontaneous labour with term delivery	0.005	0.994	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.005	0.994	0.000
O60.0 Preterm labour without delivery	0.005	0.994	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.005	0.994	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.005	0.994	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.005	0.994	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.005	0.994	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.005	0.994	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.005	0.994	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.005	0.994	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.005	0.994	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.005	0.994	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.005	0.994	0.000
K72.9 Hepatic failure, unspecified	0.006	0.994	0.000
O07 Failed attempted abortion	0.006	0.994	0.000
O06 Unspecified abortion	0.006	0.994	0.000
O05 Other abortion	0.006	0.994	0.000
O01 Hydatidiform mole	0.006	0.994	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.994	0.006
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.994	0.005
O85-O92 Complications predominantly related to the puerperium	0.005	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.995	0.005
O08 Complications following abortion and ectopic and molar pregnancy	0.005	0.995	0.000
O12.1 Gestational proteinuria	0.005	0.995	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.005	0.995	0.000
O43 Placental disorders	0.005	0.995	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
O03.3 Incomplete, with other and unspecified complications	0.005	0.995	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
O41 Other disorders of amniotic fluid and membranes	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.005	0.995	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.995	0.005
O40 Polyhydramnios	0.005	0.995	0.000
O00 Ectopic pregnancy	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T50.5 Appetite depressants	0.005	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.005	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.995	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.995	0.005
O67.9 Intrapartum haemorrhage, unspecified	0.005	0.995	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.005	0.995	0.000
O14.0 Moderate preeclampsia	0.005	0.995	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.995	0.005
O20.9 Haemorrhage in early pregnancy, unspecified	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
J43 Emphysema	0.005	0.995	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.995	0.005
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.005	0.995	0.000
O30 Multiple gestation	0.005	0.995	0.000
O03.7 Complete or unspecified, complicated by embolism	0.005	0.995	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.005	0.995	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.005	0.995	0.000
O03.2 Incomplete, complicated by embolism	0.005	0.995	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.005	0.995	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O42 Premature rupture of membranes	0.005	0.995	0.000
O03.4 Incomplete, without complication	0.005	0.995	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.995	0.005
O12.2 Gestational oedema with proteinuria	0.005	0.995	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.995	0.005
O72.1 Other immediate postpartum haemorrhage	0.005	0.995	0.000
O12.0 Gestational oedema	0.005	0.995	0.000
O31 Complications specific to multiple gestation	0.005	0.995	0.000
O41.0 Oligohydramnios	0.005	0.995	0.000
O43.1 Malformation of placenta	0.005	0.995	0.000
O03.9 Complete or unspecified, without complication	0.005	0.995	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.995	0.005
O72.3 Postpartum coagulation defects	0.004	0.995	0.000
J43.2 Centrilobular emphysema	0.005	0.995	0.000
O14.1 Severe preeclampsia	0.004	0.995	0.000
O04 Medical abortion	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.004	0.995	0.000
O87 Venous complications in the puerperium	0.004	0.995	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.995	0.004
O20 Haemorrhage in early pregnancy	0.004	0.995	0.000
O15.9 Eclampsia, unspecified as to time period	0.004	0.996	0.000
O15.2 Eclampsia in the puerperium	0.004	0.996	0.000
O15.1 Eclampsia in labour	0.004	0.996	0.000
O15.0 Eclampsia in pregnancy	0.004	0.996	0.000
O33.9 Maternal care for disproportion, unspecified	0.004	0.996	0.000
O70 Perineal laceration during delivery	0.004	0.996	0.000
O14.2 HELLP syndrome	0.004	0.996	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.996	0.004
O97 Death from sequelae of direct obstetric causes	0.004	0.996	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.996	0.000
O95 Obstetric death of unspecified cause	0.004	0.996	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O71.8 Other specified obstetric trauma	0.004	0.996	0.000
O63.0 Prolonged first stage (of labour)	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
M25.4 Effusion of joint	0.004	0.996	0.000
O01.9 Hydatidiform mole, unspecified	0.004	0.996	0.000
O01.1 Incomplete and partial hydatidiform mole	0.004	0.996	0.000
O01.0 Classical hydatidiform mole	0.004	0.996	0.000
O05.9 Complete or unspecified, without complication	0.004	0.996	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
O05.7 Complete or unspecified, complicated by embolism	0.004	0.996	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O05.4 Incomplete, without complication	0.004	0.996	0.000
O05.3 Incomplete, with other and unspecified complications	0.004	0.996	0.000
O05.2 Incomplete, complicated by embolism	0.004	0.996	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O06.9 Complete or unspecified, without complication	0.004	0.996	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
O06.7 Complete or unspecified, complicated by embolism	0.004	0.996	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O06.4 Incomplete, without complication	0.004	0.996	0.000
O06.3 Incomplete, with other and unspecified complications	0.004	0.996	0.000
O06.2 Incomplete, complicated by embolism	0.004	0.996	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.004	0.996	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.004	0.996	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.004	0.996	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O07.4 Failed medical abortion, without complication	0.004	0.996	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.004	0.996	0.000
O07.2 Failed medical abortion, complicated by embolism	0.004	0.996	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O91 Infections of breast associated with childbirth	0.004	0.996	0.000
O89 Complications of anaesthesia during the puerperium	0.004	0.996	0.000
O88 Obstetric embolism	0.004	0.996	0.000
O04.4 Incomplete, without complication	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
O28 Abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.004	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.004	0.996	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.004	0.996	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
O43.8 Other placental disorders	0.004	0.996	0.000
O43.9 Placental disorder, unspecified	0.004	0.996	0.000
O43.2 Morbidly adherent placenta	0.004	0.996	0.000
O43.0 Placental transfusion syndromes	0.004	0.996	0.000
O87.8 Other venous complications in the puerperium	0.004	0.996	0.000
O29 Complications of anaesthesia during pregnancy	0.004	0.996	0.000
O23 Infections of genito-urinary tract in pregnancy	0.004	0.996	0.000
O22 Venous complications in pregnancy	0.004	0.996	0.000
O21 Excessive vomiting in pregnancy	0.004	0.996	0.000
O25 Malnutrition in pregnancy	0.004	0.996	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.004	0.996	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.004	0.996	0.000
O41.1 Infection of amniotic sac and membranes	0.004	0.996	0.000
O33.8 Maternal care for disproportion of other origin	0.004	0.996	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.004	0.996	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.004	0.996	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.004	0.996	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.004	0.996	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.004	0.996	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.004	0.996	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.004	0.996	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.004	0.996	0.000
O90.9 Complication of the puerperium, unspecified	0.004	0.996	0.000
J43.8 Other emphysema	0.004	0.996	0.000
O00.8 Other ectopic pregnancy	0.004	0.996	0.000
O00.2 Ovarian pregnancy	0.004	0.996	0.000
O00.0 Abdominal pregnancy	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.004	0.996	0.000
O85 Puerperal sepsis	0.004	0.996	0.000
O30.0 Twin pregnancy	0.004	0.996	0.000
O00.1 Tubal pregnancy	0.004	0.996	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O80-O84 Delivery	0.004	0.996	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.004	0.996	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.004	0.996	0.000
O64.5 Obstructed labour due to compound presentation	0.004	0.996	0.000
O64.4 Obstructed labour due to shoulder presentation	0.004	0.996	0.000
O64.3 Obstructed labour due to brow presentation	0.004	0.996	0.000
O64.2 Obstructed labour due to face presentation	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
J43.1 Panlobular emphysema	0.004	0.996	0.000
J43.0 MacLeod's syndrome	0.004	0.996	0.000
O30.9 Multiple gestation, unspecified	0.004	0.996	0.000
O30.8 Other multiple gestation	0.004	0.996	0.000
O30.2 Quadruplet pregnancy	0.004	0.996	0.000
O30.1 Triplet pregnancy	0.004	0.996	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.004	0.996	0.000
O90.0 Disruption of Caesarean section wound	0.004	0.996	0.000
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O31.8 Other complications specific to multiple gestation	0.003	0.996	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.996	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.996	0.000
O31.0 Papyraceous foetus	0.003	0.996	0.000
N64.1 Fat necrosis of breast	0.004	0.996	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.996	0.003
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.004	0.996	0.000
M25.40 Effusion of joint (Multiple sites)	0.003	0.996	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.996	0.000
O44 Placenta praevia	0.003	0.996	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.003	0.996	0.000
O04.7 Complete or unspecified, complicated by embolism	0.003	0.996	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.003	0.996	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.003	0.996	0.000
O04.3 Incomplete, with other and unspecified complications	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations