TreeWAS – Variant ID: rs10968749

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.994	0.006
M20-M25 Other joint disorders	0.990	0.010
Chapter VIII Diseases of the ear and mastoid process	0.987	0.013
M65-M68 Disorders of synovium and tendon	0.980	0.020
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.979	0.021
S40-S49 Injuries to the shoulder and upper arm	0.978	0.022
M25 Other joint disorders, not elsewhere classified	0.978	0.022
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.967	0.033
Chapter XXII Codes for special purposes	0.963	0.037
M65 Synovitis and tenosynovitis	0.963	0.037
Chapter XII Diseases of the skin and subcutaneous tissue	0.961	0.039
H65-H75 Diseases of middle ear and mastoid	0.947	0.053
M25.5 Pain in joint	0.946	0.054
Chapter I Certain infectious and parasitic diseases	0.946	0.054
M25.7 Osteophyte	0.938	0.062
M24 Other specific joint derangements	0.937	0.063
T81 Complications of procedures, not elsewhere classified	0.936	0.064
T87 Complications peculiar to reattachment and amputation	0.935	0.065
M15-M19 Arthrosis	0.930	0.070
L80-L99 Other disorders of the skin and subcutaneous tissue	0.930	0.070
T81.4 Infection following a procedure, not elsewhere classified	0.929	0.071
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.928	0.072
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.928	0.072
S10-S19 Injuries to the neck	0.927	0.073
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.927	0.073
M19 Other arthrosis	0.927	0.073
M65.9 Synovitis and tenosynovitis, unspecified	0.917	0.083
M19.9 Arthrosis, unspecified	0.911	0.089
M40-M43 Deforming dorsopathies	0.908	0.092
U80 Agent resistant to penicillin and related antibiotics	0.902	0.098
H90-H95 Other disorders of ear	0.902	0.098
T93 Sequelae of injuries of lower limb	0.898	0.102
L50-L54 Urticaria and erythema	0.897	0.103
Chapter VI Diseases of the nervous system	0.896	0.104
S42 Fracture of shoulder and upper arm	0.893	0.107
T87.6 Other and unspecified complications of amputation stump	0.882	0.118
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.881	0.119
M19.0 Primary arthrosis of other joints	0.880	0.120
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.879	0.121
T36-T50 Poisoning by drugs, medicaments and biological substances	0.878	0.122
M21 Other acquired deformities of limbs	0.876	0.124
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.876	0.124
U80.1 Methicillin resistant agent	0.871	0.129
M65.3 Trigger finger	0.867	0.133
M86-M90 Other osteopathies	0.867	0.133
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.865	0.134
S40 Superficial injury of shoulder and upper arm	0.865	0.135
M19.94 Arthrosis, unspecified (Hand)	0.862	0.138
S20-S29 Injuries to the thorax	0.857	0.143
M25.57 Pain in joint (Ankle and foot)	0.851	0.149
L82 Seborrhoeic keratosis	0.847	0.153
Y85 Sequelae of transport accidents	0.847	0.153
M05-M14 Inflammatory polyarthropathies	0.845	0.155
M25.71 Osteophyte (Shoulder region)	0.845	0.155
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.843	0.157
M25.74 Osteophyte (Hand)	0.843	0.157
Y83.1 Surgical operation with implant of artificial internal device	0.841	0.159
M43 Other deforming dorsopathies	0.835	0.165
M25.53 Pain in joint (Forearm)	0.835	0.165
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.833	0.167
M24.1 Other articular cartilage disorders	0.824	0.176
H66 Suppurative and unspecified otitis media	0.823	0.177
M45-M49 Spondylopathies	0.823	0.177
M10 Gout	0.819	0.181
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.815	0.185
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.814	0.186
M25.75 Osteophyte (Pelvic region and thigh)	0.811	0.189
L89 Decubitus ulcer	0.811	0.189
M66 Spontaneous rupture of synovium and tendon	0.809	0.191
G35-G37 Demyelinating diseases of the central nervous system	0.808	0.192
T88 Other complications of surgical and medical care, not elsewhere classified	0.806	0.194
H74 Other disorders of middle ear and mastoid	0.801	0.198
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.801	0.199
A30-A49 Other bacterial diseases	0.801	0.199
M10.9 Gout, unspecified	0.801	0.199
L50 Urticaria	0.800	0.200
M65.34 Trigger finger-Hand	0.799	0.201
M25.50 Pain in joint (Multiple sites)	0.797	0.203
Chapter IV Endocrine, nutritional and metabolic diseases	0.797	0.203
M19.99 Arthrosis, unspecified (Site unspecified)	0.794	0.206
L97 Ulcer of lower limb, not elsewhere classified	0.793	0.207
M19.93 Arthrosis, unspecified (Forearm)	0.791	0.209
T90 Sequelae of injuries of head	0.788	0.212
S42.2 Fracture of upper end of humerus	0.787	0.212
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.787	0.213
T81.3 Disruption of operation wound, not elsewhere classified	0.785	0.215
H71 Cholesteatoma of middle ear	0.783	0.216
Y00-Y09 Assault	0.780	0.220
W20-W49 Exposure to inanimate mechanical forces	0.779	0.221
T87.4 Infection of amputation stump	0.779	0.221
M91-M94 Chondropathies	0.779	0.221
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.777	0.223
M19.91 Arthrosis, unspecified (Shoulder region)	0.776	0.224
Y40 Systemic antibiotics	0.774	0.226
M25.55 Pain in joint (Pelvic region and thigh)	0.774	0.226
H66.3 Other chronic suppurative otitis media	0.773	0.227
M19.04 Primary arthrosis of other joints (Hand)	0.770	0.230
Y85.0 Sequelae of motor-vehicle accident	0.770	0.230
M48 Other spondylopathies	0.769	0.231
H93 Other disorders of ear, not elsewhere classified	0.768	0.232
Y83.4 Other reconstructive surgery	0.767	0.233
V10-V19 Pedal cyclist injured in transport accident	0.767	0.233
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.766	0.234
S14 Injury of nerves and spinal cord at neck level	0.765	0.235
M25.52 Pain in joint (Upper arm)	0.765	0.235
M43.1 Spondylolisthesis	0.763	0.237
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.761	0.239
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.761	0.239
T92 Sequelae of injuries of upper limb	0.759	0.241
T98 Sequelae of other and unspecified effects of external causes	0.757	0.243
T51 Toxic effect of alcohol	0.756	0.244
H90 Conductive and sensorineural hearing loss	0.755	0.245
H73 Other disorders of tympanic membrane	0.755	0.245
M24.0 Loose body in joint	0.755	0.245
E65-E68 Obesity and other hyperalimentation	0.755	0.245
H60-H62 Diseases of external ear	0.753	0.247
M65.8 Other synovitis and tenosynovitis	0.753	0.247
H92 Otalgia and effusion of ear	0.752	0.248
B65-B83 Helminthiases	0.751	0.249
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.750	0.250
M60-M63 Disorders of muscles	0.750	0.250
B95-B98 Bacterial, viral and other infectious agents	0.750	0.250
Y86 Sequelae of other accidents	0.750	0.250
H69 Other disorders of Eustachian tube	0.747	0.253
W50-W64 Exposure to animate mechanical forces	0.746	0.253
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.745	0.255
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.744	0.256
M19.01 Primary arthrosis of other joints (Shoulder region)	0.744	0.256
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.744	0.256
M24.2 Disorder of ligament	0.744	0.256
A00-A09 Intestinal infectious diseases	0.743	0.257
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.742	0.258
S49 Other and unspecified injuries of shoulder and upper arm	0.741	0.259
A49 Bacterial infection of unspecified site	0.741	0.259
L94 Other localised connective tissue disorders	0.739	0.261
H72 Perforation of tympanic membrane	0.739	0.261
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.739	0.261
M24.8 Other specific joint derangements, not elsewhere classified	0.738	0.262
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.738	0.262
G35 Multiple sclerosis	0.737	0.263
Y89 Sequelae of other external causes	0.736	0.264
L20-L30 Dermatitis and eczema	0.734	0.266
L52 Erythema nodosum	0.734	0.266
Y83.5 Amputation of limb(s)	0.734	0.266
M48.0 Spinal stenosis	0.733	0.267
H80-H83 Diseases of inner ear	0.733	0.267
S13.4 Sprain and strain of cervical spine	0.732	0.268
M10.97 Gout, unspecified (Ankle and foot)	0.732	0.268
X58-X59 Accidental exposure to other and unspecified factors	0.732	0.268
L85 Other epidermal thickening	0.732	0.268
M21.6 Other acquired deformities of ankle and foot	0.731	0.269
Y47 Sedatives, hypnotics and antianxiety drugs	0.731	0.269
V40-V49 Car occupant injured in transport accident	0.730	0.270
L80 Vitiligo	0.730	0.270
M87 Osteonecrosis	0.729	0.271
T91 Sequelae of injuries of neck and trunk	0.727	0.273
E66 Obesity	0.724	0.276
M10.99 Gout, unspecified (Site unspecified)	0.724	0.276
L40-L45 Papulosquamous disorders	0.723	0.277
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.721	0.279
U80.0 Penicillin resistant agent	0.721	0.279
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.720	0.280
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.720	0.280
X40-X49 Accidental poisoning by and exposure to noxious substances	0.720	0.280
M25.9 Joint disorder, unspecified	0.720	0.280
A80-A89 Viral infections of the central nervous system	0.719	0.281
G00-G09 Inflammatory diseases of the central nervous system	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284
M25.77 Osteophyte (Ankle and foot)	0.715	0.285
Chapter VII Diseases of the eye and adnexa	0.715	0.285
Y40.0 Penicillins	0.714	0.286
M40 Kyphosis and lordosis	0.714	0.286
E66.9 Obesity, unspecified	0.714	0.286
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.714	0.286
B99-B99 Other infectious diseases	0.713	0.287
L81 Other disorders of pigmentation	0.713	0.287
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.712	0.287
Y35-Y36 Legal intervention and operations of war	0.712	0.287
Y10-Y34 Event of undetermined intent	0.712	0.287
X85-X99 Assault	0.712	0.287
X50-X57 Overexertion, travel and privation	0.712	0.287
X30-X39 Exposure to forces of nature	0.712	0.287
X20-X29 Contact with venomous animals and plants	0.712	0.287
X10-X19 Contact with heat and hot substances	0.712	0.287
X00-X09 Exposure to smoke, fire and flames	0.712	0.287
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.712	0.287
W75-W84 Other accidental threats to breathing	0.712	0.287
W65-W74 Accidental drowning and submersion	0.712	0.287
V98-V99 Other and unspecified transport accidents	0.712	0.287
V95-V97 Air and space transport accidents	0.712	0.287
V90-V94 Water transport accidents	0.712	0.287
V70-V79 Bus occupant injured in transport accident	0.712	0.287
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.712	0.287
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.712	0.287
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.712	0.287
V01-V09 Pedestrian injured in transport accident	0.712	0.287
S42.20 Fracture of upper end of humerus (closed)	0.712	0.288
M48.02 Spinal stenosis (Cervical region)	0.710	0.290
L53 Other erythematous conditions	0.710	0.290
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.290
M33 Dermatopolymyositis	0.709	0.290
M32 Systemic lupus erythematosus	0.709	0.290
M30 Polyarteritis nodosa and related conditions	0.709	0.290
S19 Other and unspecified injuries of neck	0.709	0.291
S10 Superficial injury of neck	0.707	0.293
T93.9 Sequelae of unspecified injury of lower limb	0.707	0.293
M25.3 Other instability of joint	0.707	0.293
S42.3 Fracture of shaft of humerus	0.707	0.293
G70-G73 Diseases of myoneural junction and muscle	0.707	0.293
B35-B49 Mycoses	0.706	0.294
M80-M85 Disorders of bone density and structure	0.706	0.294
M24.4 Recurrent dislocation and subluxation of joint	0.706	0.294
S80-S89 Injuries to the knee and lower leg	0.705	0.295
S20 Superficial injury of thorax	0.704	0.296
B20-B24 Human immunodeficiency virus [HIV] disease	0.703	0.296
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.703	0.297
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.703	0.297
L95 Vasculitis limited to skin, not elsewhere classified	0.703	0.297
A49.0 Staphylococcal infection, unspecified	0.703	0.297
M43.16 Spondylolisthesis (Lumbar region)	0.702	0.298
T93.1 Sequelae of fracture of femur	0.702	0.298
S48 Traumatic amputation of shoulder and upper arm	0.701	0.299
S46 Injury of muscle and tendon at shoulder and upper arm level	0.701	0.299
S45 Injury of blood vessels at shoulder and upper arm level	0.701	0.299
S44 Injury of nerves at shoulder and upper arm level	0.701	0.299
S41 Open wound of shoulder and upper arm	0.701	0.299
S47 Crushing injury of shoulder and upper arm	0.701	0.299
M25.2 Flail joint	0.701	0.299
M25.1 Fistula of joint	0.701	0.299
M25.0 Haemarthrosis	0.701	0.299
S40.0 Contusion of shoulder and upper arm	0.701	0.299
M19.98 Arthrosis, unspecified (Other)	0.701	0.299
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.700	0.300
Y57 Other and unspecified drugs and medicaments	0.700	0.300
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.700	0.300
X60-X84 Intentional self-harm	0.700	0.300
T79-T79 Certain early complications of trauma	0.700	0.300
B15-B19 Viral hepatitis	0.699	0.301
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.698	0.302
L89.0 Stage I decubitus ulcer and pressure area	0.698	0.302
S42.4 Fracture of lower end of humerus	0.695	0.305
L84 Corns and callosities	0.695	0.305
T95 Sequelae of burns, corrosions and frostbite	0.693	0.306
T94 Sequelae of injuries involving multiple and unspecified body regions	0.693	0.306
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.693	0.306
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.693	0.306
U80.8 Agent resistant to other penicillin-related antibiotic	0.693	0.306
M31 Other necrotising vasculopathies	0.693	0.307
W00-W19 Falls	0.693	0.307
S27 Injury of other and unspecified intrathoracic organs	0.693	0.307
M00-M03 Infectious arthropathies	0.693	0.307
L50.9 Urticaria, unspecified	0.692	0.308
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.692	0.308
S90-S99 Injuries to the ankle and foot	0.691	0.309
T15-T19 Effects of foreign body entering through natural orifice	0.691	0.309
S43.1 Dislocation of acromioclavicular joint	0.691	0.309
M21.4 Flat foot [pes planus] (acquired)	0.691	0.309
M65.2 Calcific tendinitis	0.690	0.310
M65.1 Other infective (teno)synovitis	0.690	0.310
M65.0 Abscess of tendon sheath	0.690	0.310
S30 Superficial injury of abdomen, lower back and pelvis	0.690	0.310
L10-L14 Bullous disorders	0.689	0.311
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.688	0.312
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.688	0.312
M65.4 Radial styloid tenosynovitis [de Quervain]	0.687	0.313
T80 Complications following infusion, transfusion and therapeutic injection	0.684	0.316
T84.1 Mechanical complication of internal fixation device of bones of limb	0.683	0.317
M19.90 Arthrosis, unspecified (Multiple sites)	0.681	0.319
V80-V89 Other land transport accidents	0.680	0.320
S42.0 Fracture of clavicle	0.680	0.320
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.679	0.321
H70 Mastoiditis and related conditions	0.679	0.321
H68 Eustachian salpingitis and obstruction	0.679	0.321
H67 Otitis media in diseases classified elsewhere	0.679	0.321
T46 Poisoning by agents primarily affecting the cardiovascular system	0.679	0.321
M25.72 Osteophyte (Upper arm)	0.679	0.321
M25.58 Pain in joint (Other)	0.678	0.322
B90-B94 Sequelae of infectious and parasitic diseases	0.678	0.322
B85-B89 Pediculosis, acariasis and other infestations	0.678	0.322
B50-B64 Protozoal diseases	0.678	0.322
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.678	0.322
A75-A79 Rickettsioses	0.678	0.322
A70-A74 Other diseases caused by chlamydiae	0.678	0.322
A65-A69 Other spirochaetal diseases	0.678	0.322
A20-A28 Certain zoonotic bacterial diseases	0.678	0.322
A15-A19 Tuberculosis	0.678	0.322
S36 Injury of intra-abdominal organs	0.677	0.323
L91 Hypertrophic disorders of skin	0.675	0.325
G30-G32 Other degenerative diseases of the nervous system	0.675	0.325
H74.4 Polyp of middle ear	0.674	0.326
Y83.2 Surgical operation with anastomosis, bypass or graft	0.673	0.327
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.673	0.327
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.673	0.327
M25.79 Osteophyte (Site unspecified)	0.672	0.327
M25.73 Osteophyte (Forearm)	0.672	0.327
M25.70 Osteophyte (Multiple sites)	0.672	0.327
M24.9 Joint derangement, unspecified	0.672	0.328
M24.7 Protrusio acetabuli	0.672	0.328
M24.6 Ankylosis of joint	0.672	0.328
M24.5 Contracture of joint	0.672	0.328
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.672	0.328
M90 Osteopathies in diseases classified elsewhere	0.671	0.329
M22 Disorders of patella	0.671	0.329
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.671	0.329
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.671	0.329
T87.5 Necrosis of amputation stump	0.671	0.329
T87.3 Neuroma of amputation stump	0.671	0.329
T87.2 Complications of other reattached body part	0.671	0.329
T87.1 Complications of reattached (part of) lower extremity	0.671	0.329
T87.0 Complications of reattached (part of) upper extremity	0.671	0.329
T93.2 Sequelae of other fractures of lower limb	0.670	0.330
M24.16 Other articular cartilage disorders (Lower leg)	0.670	0.330
Y85.9 Sequelae of other and unspecified transport accidents	0.670	0.330
M25.8 Other specified joint disorders	0.669	0.331
T39.1 4-Aminophenol derivatives	0.669	0.331
T90.9 Sequelae of unspecified injury of head	0.669	0.331
A04 Other bacterial intestinal infections	0.668	0.332
M15 Polyarthrosis	0.667	0.333
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.667	0.333
L87 Transepidermal elimination disorders	0.667	0.333
L88 Pyoderma gangrenosum	0.667	0.333
L86 Keratoderma in diseases classified elsewhere	0.667	0.333
L83 Acanthosis nigricans	0.667	0.333
M25.56 Pain in joint (Lower leg)	0.665	0.335
L93 Lupus erythematosus	0.665	0.335
U81 Agent resistant to vancomycin and related antibiotics	0.665	0.335
U51 Admission status on psychiatric patients	0.665	0.335
U50 Level of care administered to neonates	0.665	0.335
U07 Emergency use of U07	0.665	0.335
U06 Emergency use of U06	0.665	0.335
U04 Severe acute respiratory syndrome [SARS]	0.665	0.335
U52 First in a series of a regular day/night admissions	0.665	0.335
S17 Crushing injury of neck	0.665	0.335
S15 Injury of blood vessels at neck level	0.665	0.335
S11 Open wound of neck	0.665	0.335
S18 Traumatic amputation at neck level	0.665	0.335
S16 Injury of muscle and tendon at neck level	0.665	0.335
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.665	0.335
M19.8 Other specified arthrosis	0.664	0.336
M19.2 Other secondary arthrosis	0.664	0.336
T81.7 Vascular complications following a procedure, not elsewhere classified	0.664	0.336
M43.0 Spondylolysis	0.664	0.336
M10.90 Gout, unspecified (Multiple sites)	0.663	0.337
M21.3 Wrist or foot drop (acquired)	0.663	0.337
A50-A64 Infections with a predominantly sexual mode of transmission	0.661	0.338
S43.0 Dislocation of shoulder joint	0.661	0.339
M21.1 Varus deformity, not elsewhere classified	0.661	0.339
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.660	0.340
V20-V29 Motorcycle rider injured in transport accident	0.659	0.340
S50-S59 Injuries to the elbow and forearm	0.659	0.341
M25.78 Osteophyte (Other)	0.658	0.342
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.657	0.343
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.657	0.343
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.657	0.343
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.657	0.343
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.657	0.343
L50.0 Allergic urticaria	0.655	0.345
T51.0 Ethanol	0.655	0.345
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.652	0.348
T59 Toxic effect of other gases, fumes and vapours	0.652	0.348
M42 Spinal osteochondrosis	0.651	0.349
G90-G99 Other disorders of the nervous system	0.651	0.349
M89 Other disorders of bone	0.650	0.350
S12 Fracture of neck	0.650	0.350
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.650	0.350
L89.2 Stage III decubitus ulcer	0.650	0.350
M25.6 Stiffness of joint, not elsewhere classified	0.648	0.351
S14.1 Other and unspecified injuries of cervical spinal cord	0.648	0.352
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.647	0.353
H94 Other disorders of ear in diseases classified elsewhere	0.647	0.353
M66.4 Spontaneous rupture of other tendons	0.647	0.353
H43-H45 Disorders of vitreous body and globe	0.646	0.354
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.646	0.354
Y60-Y69 Misadventures to patients during surgical and medical care	0.645	0.355
T93.8 Sequelae of other specified injuries of lower limb	0.644	0.356
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.644	0.356
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.644	0.356
T93.4 Sequelae of injury of nerve of lower limb	0.644	0.356
T93.0 Sequelae of open wound of lower limb	0.644	0.356
L54 Erythema in diseases classified elsewhere	0.643	0.357
L51 Erythema multiforme	0.643	0.357
H93.1 Tinnitus	0.642	0.358
M25.59 Pain in joint (Site unspecified)	0.642	0.358
E10-E14 Diabetes mellitus	0.641	0.359
S42.9 Fracture of shoulder girdle, part unspecified	0.640	0.360
S42.8 Fracture of other parts of shoulder and upper arm	0.640	0.360
S42.7 Multiple fractures of clavicle, scapula and humerus	0.640	0.360
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.639	0.361
M24.11 Other articular cartilage disorders (Shoulder region)	0.637	0.363
L29 Pruritus	0.637	0.363
M34 Systemic sclerosis	0.637	0.363
M66.0 Rupture of popliteal cyst	0.637	0.363
S29 Other and unspecified injuries of thorax	0.634	0.366
D60-D64 Aplastic and other anaemias	0.633	0.367
Y51 Drugs primarily affecting the autonomic nervous system	0.632	0.368
M24.13 Other articular cartilage disorders (Forearm)	0.632	0.368
M19.08 Primary arthrosis of other joints (Other)	0.631	0.369
M19.06 Primary arthrosis of other joints-Lower leg	0.631	0.369
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.631	0.369
M19.03 Primary arthrosis of other joints (Forearm)	0.631	0.369
M19.02 Primary arthrosis of other joints (Upper arm)	0.631	0.369
M19.00 Primary arthrosis of other joints (Multiple sites)	0.631	0.369
T86 Failure and rejection of transplanted organs and tissues	0.631	0.369
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.631	0.369
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.630	0.370
S37 Injury of urinary and pelvic organs	0.630	0.370
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.630	0.370
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.630	0.370
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.630	0.370
S31 Open wound of abdomen, lower back and pelvis	0.630	0.370
L85.8 Other specified epidermal thickening	0.630	0.370
M25.51 Pain in joint (Shoulder region)	0.630	0.370
W29 Contact with other powered hand tools and household machinery	0.630	0.370
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.629	0.371
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.629	0.371
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.629	0.371
T41 Poisoning by anaesthetics and therapeutic gases	0.629	0.371
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.629	0.371
T36 Poisoning by systemic antibiotics	0.629	0.371
M86 Osteomyelitis	0.629	0.371
M48.07 Spinal stenosis (Lumbosacral region)	0.629	0.371
M21.9 Acquired deformity of limb, unspecified	0.628	0.372
M21.8 Other specified acquired deformities of limbs	0.628	0.372
M21.7 Unequal limb length (acquired)	0.628	0.372
M21.2 Flexion deformity	0.628	0.372
G50-G59 Nerve, nerve root and plexus disorders	0.628	0.372
Y59 Other and unspecified vaccines and biological substances	0.628	0.372
Y58 Bacterial vaccines	0.628	0.372
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.628	0.372
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.628	0.372
Y53 Agents primarily affecting the gastro-intestinal system	0.628	0.372
Y50 Central nervous system stimulants, not elsewhere classified	0.628	0.372
Y49 Psychotropic drugs, not elsewhere classified	0.628	0.372
Y48 Anaesthetics and therapeutic gases	0.628	0.372
Y46 Antiepileptics and anti-Parkinsonism drugs	0.628	0.372
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.628	0.372
Y44 Agents primarily affecting blood constituents	0.628	0.372
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.627	0.373
G12 Spinal muscular atrophy and related syndromes	0.627	0.373
Y00 Assault by blunt object	0.627	0.373
Y47.1 Benzodiazepines	0.627	0.373
Y83.6 Removal of other organ (partial) (total)	0.623	0.377
T83.3 Mechanical complication of intra-uterine contraceptive device	0.622	0.378
M65.39 Trigger finger-Site unspec	0.622	0.378
M65.38 Trigger finger-Other	0.622	0.378
M65.37 Trigger finger-Ankle/foot	0.622	0.378
M65.36 Trigger finger-Lower leg	0.622	0.378
M65.35 Trigger finger-Pelvic/thigh	0.622	0.378
M65.33 Trigger finger-Forearm	0.622	0.378
M65.32 Trigger finger-Upper arm	0.622	0.378
M65.31 Trigger finger-Shldr region	0.622	0.378
M65.30 Trigger finger-Mult sites	0.622	0.378
L92 Granulomatous disorders of skin and subcutaneous tissue	0.622	0.378
H55-H59 Other disorders of eye and adnexa	0.621	0.379
T65 Toxic effect of other and unspecified substances	0.620	0.379
T62 Toxic effect of other noxious substances eaten as food	0.620	0.379
T61 Toxic effect of noxious substances eaten as seafood	0.620	0.379
T60 Toxic effect of pesticides	0.620	0.379
T57 Toxic effect of other inorganic substances	0.620	0.379
T56 Toxic effect of metals	0.620	0.379
T54 Toxic effect of corrosive substances	0.620	0.379
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.620	0.379
T52 Toxic effect of organic solvents	0.620	0.379
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.620	0.379
T58 Toxic effect of carbon monoxide	0.620	0.379
T55 Toxic effect of soaps and detergents	0.620	0.379
S40.8 Other superficial injuries of shoulder and upper arm	0.620	0.380
S40.7 Multiple superficial injuries of shoulder and upper arm	0.620	0.380
M88 Paget's disease of bone [osteitis deformans]	0.619	0.381
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.618	0.382
T90.4 Sequelae of injury of eye and orbit	0.618	0.382
H92.0 Otalgia	0.618	0.382
T63 Toxic effect of contact with venomous animals	0.618	0.382
M19.1 Posttraumatic arthrosis of other joints	0.618	0.382
H73.8 Other specified disorders of tympanic membrane	0.617	0.383
H74.3 Other acquired abnormalities of ear ossicles	0.617	0.383
M67 Other disorders of synovium and tendon	0.616	0.383
H69.8 Other specified disorders of Eustachian tube	0.616	0.384
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.614	0.386
S26 Injury of heart	0.614	0.386
S25 Injury of blood vessels of thorax	0.614	0.386
S24 Injury of nerves and spinal cord at thorax level	0.614	0.386
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.614	0.386
S21 Open wound of thorax	0.614	0.386
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.614	0.386
Chapter XIV Diseases of the genitourinary system	0.613	0.387
U88 Agent resistant to multiple antibiotics	0.611	0.389
B80 Enterobiasis	0.611	0.389
A04.8 Other specified bacterial intestinal infections	0.610	0.390
T81.9 Unspecified complication of procedure	0.610	0.390
M24.17 Other articular cartilage disorders (Ankle and foot)	0.610	0.390
S20.2 Contusion of thorax	0.609	0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations