TreeWAS – Variant ID: rs11084753

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S00-S09 Injuries to the head	0.763	0.237	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.753	0.247	0.000
S90-S99 Injuries to the ankle and foot	0.749	0.251	0.000
S06 Intracranial injury	0.747	0.253	0.000
T79-T79 Certain early complications of trauma	0.744	0.256	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.742	0.258	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.740	0.260	0.000
S02 Fracture of skull and facial bones	0.739	0.261	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.738	0.262	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.735	0.265	0.000
S92 Fracture of foot, except ankle	0.726	0.274	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.725	0.275	0.000
S00 Superficial injury of head	0.723	0.277	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.722	0.278	0.000
T51 Toxic effect of alcohol	0.721	0.279	0.000
S00.0 Superficial injury of scalp	0.721	0.279	0.000
T51.0 Ethanol	0.704	0.296	0.000
S06.2 Diffuse brain injury	0.704	0.296	0.000
S92.3 Fracture of metatarsal bone	0.699	0.301	0.000
S92.30 Fracture of metatarsal bone (closed)	0.679	0.321	0.000
S06.8 Other intracranial injuries	0.678	0.322	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.672	0.328	0.000
S06.0 Concussion	0.671	0.328	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.670	0.330	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.668	0.332	0.000
T79.8 Other early complications of trauma	0.652	0.348	0.000
T59 Toxic effect of other gases, fumes and vapours	0.647	0.353	0.000
S02.2 Fracture of nasal bones	0.644	0.356	0.000
S30.0 Contusion of lower back and pelvis	0.643	0.356	0.000
S90 Superficial injury of ankle and foot	0.640	0.360	0.000
S92.5 Fracture of other toe	0.635	0.365	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.630	0.370	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.628	0.372	0.000
S02.5 Fracture of tooth	0.628	0.372	0.000
S02.8 Fractures of other skull and facial bones	0.627	0.373	0.000
S06.00 Concussion (without open intracranial wound)	0.617	0.383	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.617	0.383	0.000
T62 Toxic effect of other noxious substances eaten as food	0.613	0.387	0.000
S02.1 Fracture of base of skull	0.612	0.388	0.000
S93.1 Dislocation of toe(s)	0.610	0.390	0.000
S36 Injury of intra-abdominal organs	0.607	0.393	0.000
T59.8 Other specified gases, fumes and vapours	0.603	0.397	0.000
S37 Injury of urinary and pelvic organs	0.596	0.404	0.000
S02.0 Fracture of vault of skull	0.596	0.404	0.000
S06.3 Focal brain injury	0.594	0.406	0.000
S92.0 Fracture of calcaneus	0.592	0.408	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.586	0.414	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.586	0.414	0.000
T00-T07 Injuries involving multiple body regions	0.581	0.419	0.000
T56 Toxic effect of metals	0.577	0.423	0.000
T17 Foreign body in respiratory tract	0.575	0.425	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.574	0.426	0.000
S97 Crushing injury of ankle and foot	0.574	0.426	0.000
S02.20 Fracture of nasal bones (closed)	0.570	0.430	0.000
T79.7 Traumatic subcutaneous emphysema	0.568	0.432	0.000
S06.1 Traumatic cerebral oedema	0.564	0.436	0.000
T79.5 Traumatic anuria	0.563	0.437	0.000
S00.8 Superficial injury of other parts of head	0.562	0.438	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.561	0.439	0.000
S04 Injury of cranial nerves	0.560	0.440	0.000
S02.3 Fracture of orbital floor	0.557	0.443	0.000
S99 Other and unspecified injuries of ankle and foot	0.555	0.445	0.000
S02.7 Multiple fractures involving skull and facial bones	0.552	0.448	0.000
S00.3 Superficial injury of nose	0.551	0.449	0.000
S02.10 Fracture of base of skull (closed)	0.550	0.450	0.000
S02.50 Fracture of tooth (closed)	0.549	0.451	0.000
S00.5 Superficial injury of lip and oral cavity	0.549	0.451	0.000
S08 Traumatic amputation of part of head	0.548	0.452	0.000
S07 Crushing injury of head	0.547	0.453	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.547	0.453	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.546	0.454	0.000
T63 Toxic effect of contact with venomous animals	0.544	0.456	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.544	0.456	0.000
T51.9 Alcohol, unspecified	0.542	0.458	0.000
S90.0 Contusion of ankle	0.542	0.458	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.541	0.459	0.000
T33-T35 Frostbite	0.540	0.460	0.000
T43.2 Other and unspecified antidepressants	0.540	0.460	0.000
S31 Open wound of abdomen, lower back and pelvis	0.537	0.463	0.000
S95 Injury of blood vessels at ankle and foot level	0.537	0.463	0.000
S94 Injury of nerves at ankle and foot level	0.537	0.463	0.000
S06.7 Intracranial injury with prolonged coma	0.536	0.464	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.536	0.464	0.000
T60 Toxic effect of pesticides	0.532	0.468	0.000
T57 Toxic effect of other inorganic substances	0.532	0.468	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.532	0.468	0.000
T52 Toxic effect of organic solvents	0.532	0.468	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.532	0.468	0.000
T55 Toxic effect of soaps and detergents	0.532	0.468	0.000
T54 Toxic effect of corrosive substances	0.531	0.468	0.000
T66-T78 Other and unspecified effects of external causes	0.531	0.469	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.530	0.470	0.000
T79.9 Unspecified early complication of trauma	0.529	0.471	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.529	0.471	0.000
T79.1 Fat embolism (traumatic)	0.529	0.471	0.000
T79.0 Air embolism (traumatic)	0.529	0.471	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.529	0.471	0.000
S92.50 Fracture of other toe (closed)	0.527	0.473	0.000
S92.51 Fracture of other toe (open)	0.526	0.474	0.000
S30.2 Contusion of external genital organs	0.525	0.475	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.525	0.475	0.000
T79.6 Traumatic ischaemia of muscle	0.523	0.477	0.000
T62.9 Noxious substance eaten as food, unspecified	0.520	0.480	0.000
T51.8 Other alcohols	0.517	0.483	0.000
T51.3 Fusel oil	0.517	0.483	0.000
T51.2 2-Propanol	0.517	0.483	0.000
T51.1 Methanol	0.517	0.483	0.000
S98 Traumatic amputation of ankle and foot	0.511	0.489	0.000
T09 Other injuries of spine and trunk, level unspecified	0.511	0.489	0.000
T16 Foreign body in ear	0.510	0.489	0.000
S02.4 Fracture of malar and maxillary bones	0.510	0.490	0.000
T13 Other injuries of lower limb, level unspecified	0.507	0.493	0.000
T79.4 Traumatic shock	0.506	0.494	0.000
S10-S19 Injuries to the neck	0.506	0.494	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.505	0.495	0.000
S92.4 Fracture of great toe	0.505	0.495	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.504	0.495	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.504	0.496	0.000
S93.0 Dislocation of ankle joint	0.503	0.497	0.000
S92.31 Fracture of metatarsal bone (open)	0.501	0.499	0.000
S92.2 Fracture of other tarsal bone(s)	0.501	0.499	0.000
S91 Open wound of ankle and foot	0.501	0.499	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.500	0.500	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.500	0.500	0.000
S92.1 Fracture of talus	0.498	0.502	0.000
S90.8 Other superficial injuries of ankle and foot	0.498	0.502	0.000
S37.0 Injury of kidney	0.496	0.504	0.000
S02.00 Fracture of vault of skull (closed)	0.490	0.510	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.488	0.512	0.000
T65 Toxic effect of other and unspecified substances	0.488	0.512	0.000
S01 Open wound of head	0.487	0.513	0.000
S92.01 Fracture of calcaneus (open)	0.486	0.514	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.486	0.514	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.486	0.514	0.000
S09 Other and unspecified injuries of head	0.484	0.516	0.000
S06.5 Traumatic subdural haemorrhage	0.484	0.516	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.484	0.516	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.484	0.516	0.000
S06.01 Concussion (with open intracranial wound)	0.481	0.518	0.000
T15 Foreign body on external eye	0.481	0.519	0.000
S93.4 Sprain and strain of ankle	0.481	0.519	0.000
S93.5 Sprain and strain of toe(s)	0.481	0.519	0.000
T17.2 Foreign body in pharynx	0.480	0.520	0.000
S02.21 Fracture of nasal bones (open)	0.475	0.525	0.000
S92.7 Multiple fractures of foot	0.474	0.526	0.000
S01.9 Open wound of head, part unspecified	0.472	0.528	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.472	0.528	0.000
T43.9 Psychotropic drug, unspecified	0.472	0.528	0.000
T08 Fracture of spine, level unspecified	0.470	0.529	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.468	0.532	0.000
T68 Hypothermia	0.466	0.534	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.465	0.535	0.000
S92.9 Fracture of foot, unspecified	0.464	0.536	0.000
T59.7 Carbon dioxide	0.464	0.536	0.000
T59.6 Hydrogen sulphide	0.464	0.536	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.464	0.536	0.000
T59.4 Chlorine gas	0.464	0.536	0.000
T59.3 Lachrymogenic gas	0.464	0.536	0.000
T59.2 Formaldehyde	0.464	0.536	0.000
T59.1 Sulphur dioxide	0.464	0.536	0.000
T59.0 Nitrogen oxides	0.464	0.536	0.000
S36.1 Injury of liver or gallbladder	0.463	0.537	0.000
S36.8 Injury of other intra-abdominal organs	0.462	0.538	0.000
S99.9 Unspecified injury of ankle and foot	0.462	0.538	0.000
S05 Injury of eye and orbit	0.461	0.539	0.000
S36.0 Injury of spleen	0.461	0.539	0.000
T56.8 Other metals	0.459	0.541	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.459	0.541	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.459	0.541	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.459	0.541	0.000
S90.2 Contusion of toe(s) with damage to nail	0.459	0.541	0.000
S97.1 Crushing injury of toe(s)	0.457	0.543	0.000
S90.1 Contusion of toe(s) without damage to nail	0.454	0.545	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.454	0.546	0.000
T17.5 Foreign body in bronchus	0.452	0.548	0.000
S02.51 Fracture of tooth (open)	0.450	0.549	0.000
S02.81 Fractures of other skull and facial bones (open)	0.450	0.550	0.000
S00.4 Superficial injury of ear	0.448	0.552	0.000
T01 Open wounds involving multiple body regions	0.447	0.552	0.000
S03.0 Dislocation of jaw	0.446	0.554	0.000
T09.0 Superficial injury of trunk, level unspecified	0.445	0.555	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.444	0.556	0.000
S36.6 Injury of rectum	0.444	0.556	0.000
S36.5 Injury of colon	0.444	0.556	0.000
T00 Superficial injuries involving multiple body regions	0.444	0.556	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.444	0.556	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.443	0.557	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.442	0.558	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.442	0.558	0.000
T12 Fracture of lower limb, level unspecified	0.442	0.558	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.442	0.558	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.442	0.558	0.000
T10 Fracture of upper limb, level unspecified	0.442	0.558	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.442	0.558	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.442	0.558	0.000
S92.00 Fracture of calcaneus (closed)	0.441	0.559	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.441	0.559	0.000
S10 Superficial injury of neck	0.440	0.560	0.000
T62.8 Other specified noxious substances eaten as food	0.439	0.560	0.000
T62.2 Other ingested (parts of) plant(s)	0.439	0.560	0.000
T62.1 Ingested berries	0.439	0.560	0.000
T62.0 Ingested mushrooms	0.439	0.560	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.439	0.561	0.000
T19 Foreign body in genito-urinary tract	0.437	0.563	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.435	0.565	0.000
S36.7 Injury of multiple intra-abdominal organs	0.435	0.565	0.000
S36.3 Injury of stomach	0.435	0.565	0.000
S36.2 Injury of pancreas	0.435	0.565	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.433	0.567	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.433	0.567	0.000
T36 Poisoning by systemic antibiotics	0.433	0.567	0.000
S02.01 Fracture of vault of skull (open)	0.432	0.568	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.431	0.569	0.000
S37.3 Injury of urethra	0.431	0.569	0.000
S03.1 Dislocation of septal cartilage of nose	0.431	0.569	0.000
S36.4 Injury of small intestine	0.429	0.571	0.000
S37.9 Injury of unspecified pelvic organ	0.428	0.572	0.000
S37.8 Injury of other pelvic organs	0.428	0.572	0.000
S37.7 Injury of multiple pelvic organs	0.428	0.572	0.000
S37.6 Injury of uterus	0.428	0.572	0.000
S37.5 Injury of Fallopian tube	0.428	0.572	0.000
S37.4 Injury of ovary	0.428	0.572	0.000
S37.1 Injury of ureter	0.428	0.572	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.427	0.573	0.000
S02.30 Fracture of orbital floor (closed)	0.427	0.573	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.426	0.574	0.000
S90.3 Contusion of other and unspecified parts of foot	0.425	0.575	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.425	0.575	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.424	0.576	0.000
S03.2 Dislocation of tooth	0.424	0.576	0.000
S91.2 Open wound of toe(s) with damage to nail	0.424	0.576	0.000
T11 Other injuries of upper limb, level unspecified	0.423	0.576	0.000
T26 Burn and corrosion confined to eye and adnexa	0.423	0.577	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.421	0.579	0.000
S37.2 Injury of bladder	0.420	0.580	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.420	0.580	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.420	0.580	0.000
S03.4 Sprain and strain of jaw	0.420	0.580	0.000
S03.3 Dislocation of other and unspecified parts of head	0.420	0.580	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.420	0.580	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.419	0.581	0.000
S31.0 Open wound of lower back and pelvis	0.417	0.583	0.000
T05 Traumatic amputations involving multiple body regions	0.417	0.583	0.000
T04 Crushing injuries involving multiple body regions	0.417	0.583	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.417	0.583	0.000
T07 Unspecified multiple injuries	0.417	0.583	0.000
S06.4 Epidural haemorrhage	0.416	0.584	0.000
T56.9 Metal, unspecified	0.414	0.586	0.000
T56.7 Beryllium and its compounds	0.414	0.586	0.000
T56.6 Tin and its compounds	0.414	0.586	0.000
T56.5 Zinc and its compounds	0.414	0.586	0.000
T56.4 Copper and its compounds	0.414	0.586	0.000
T56.3 Cadmium and its compounds	0.414	0.586	0.000
T56.2 Chromium and its compounds	0.414	0.586	0.000
T56.1 Mercury and its compounds	0.414	0.586	0.000
T56.0 Lead and its compounds	0.414	0.586	0.000
S04.5 Injury of facial nerve	0.414	0.586	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.413	0.587	0.000
T71 Asphyxiation	0.413	0.587	0.000
T17.4 Foreign body in trachea	0.412	0.588	0.000
T17.1 Foreign body in nostril	0.412	0.588	0.000
T17.0 Foreign body in nasal sinus	0.412	0.588	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.412	0.588	0.000
S97.0 Crushing injury of ankle	0.411	0.588	0.000
S06.9 Intracranial injury, unspecified	0.410	0.589	0.001
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.406	0.594	0.000
S00.7 Multiple superficial injuries of head	0.406	0.594	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.405	0.595	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.404	0.595	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.402	0.598	0.000
T28 Burn and corrosion of other internal organs	0.402	0.598	0.000
T27 Burn and corrosion of respiratory tract	0.402	0.598	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.401	0.598	0.000
T61.2 Other fish and shellfish poisoning	0.401	0.598	0.000
S04.9 Injury of unspecified cranial nerve	0.401	0.599	0.000
S04.8 Injury of other cranial nerves	0.401	0.599	0.000
S04.7 Injury of accessory nerve	0.401	0.599	0.000
S04.6 Injury of acoustic nerve	0.401	0.599	0.000
S04.4 Injury of abducent nerve	0.401	0.599	0.000
S04.3 Injury of trigeminal nerve	0.401	0.599	0.000
S04.2 Injury of trochlear nerve	0.401	0.599	0.000
S04.1 Injury of oculomotor nerve	0.401	0.599	0.000
S04.0 Injury of optic nerve and pathways	0.401	0.599	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.401	0.599	0.000
T66 Unspecified effects of radiation	0.400	0.600	0.000
S02.31 Fracture of orbital floor (open)	0.399	0.600	0.000
S31.1 Open wound of abdominal wall	0.399	0.600	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.399	0.600	0.000
S99.7 Multiple injuries of ankle and foot	0.398	0.602	0.000
S12 Fracture of neck	0.397	0.603	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.396	0.604	0.000
T02 Fractures involving multiple body regions	0.396	0.604	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.395	0.605	0.000
T58 Toxic effect of carbon monoxide	0.393	0.607	0.000
S08.1 Traumatic amputation of ear	0.393	0.607	0.000
S08.9 Traumatic amputation of unspecified part of head	0.393	0.607	0.000
S08.8 Traumatic amputation of other parts of head	0.393	0.607	0.000
S08.0 Avulsion of scalp	0.393	0.607	0.000
S07.9 Crushing injury of head, part unspecified	0.392	0.607	0.000
S07.8 Crushing injury of other parts of head	0.392	0.607	0.000
S07.1 Crushing injury of skull	0.392	0.607	0.000
S07.0 Crushing injury of face	0.392	0.607	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.392	0.608	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.392	0.608	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.391	0.609	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.391	0.609	0.000
S09.7 Multiple injuries of head	0.391	0.609	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.391	0.609	0.000
T63.8 Toxic effect of contact with other venomous animals	0.390	0.610	0.000
T63.6 Toxic effect of contact with other marine animals	0.390	0.610	0.000
T63.5 Toxic effect of contact with fish	0.390	0.610	0.000
T63.3 Venom of spider	0.390	0.610	0.000
T63.2 Venom of scorpion	0.390	0.610	0.000
T63.1 Venom of other reptiles	0.390	0.610	0.000
T63.0 Snake venom	0.390	0.610	0.000
T61.9 Toxic effect of unspecified seafood	0.390	0.610	0.000
T61.8 Toxic effect of other seafoods	0.390	0.610	0.000
T61.1 Scombroid fish poisoning	0.390	0.610	0.000
T61.0 Ciguatera fish poisoning	0.390	0.610	0.000
S01.7 Multiple open wounds of head	0.390	0.610	0.000
S09.8 Other specified injuries of head	0.389	0.610	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.388	0.612	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.388	0.612	0.000
S10.9 Superficial injury of neck, part unspecified	0.388	0.612	0.000
T75 Effects of other external causes	0.387	0.613	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.387	0.613	0.000
T34 Frostbite with tissue necrosis	0.387	0.613	0.000
T33 Superficial frostbite	0.387	0.613	0.000
T15.9 Foreign body on external eye, unspecified	0.387	0.613	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.385	0.615	0.000
S31.5 Open wound of other and unspecified external genital organs	0.385	0.615	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.385	0.615	0.000
S94.8 Injury of other nerves at ankle and foot level	0.385	0.615	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.385	0.615	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.385	0.615	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.385	0.615	0.000
S94.1 Injury of medial plantar nerve	0.385	0.615	0.000
S94.0 Injury of lateral plantar nerve	0.385	0.615	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.385	0.615	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.385	0.615	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.385	0.615	0.000
S95.2 Injury of dorsal vein of foot	0.385	0.615	0.000
S95.1 Injury of plantar artery of foot	0.385	0.615	0.000
S95.0 Injury of dorsal artery of foot	0.385	0.615	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.384	0.615	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.384	0.615	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.384	0.616	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.384	0.616	0.000
S31.3 Open wound of scrotum and testes	0.384	0.616	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.383	0.617	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.382	0.618	0.000
T52.9 Organic solvent, unspecified	0.381	0.618	0.000
T52.8 Other organic solvents	0.381	0.618	0.000
T52.4 Ketones	0.381	0.618	0.000
T52.3 Glycols	0.381	0.618	0.000
T52.2 Homologues of benzene	0.381	0.618	0.000
T52.1 Benzene	0.381	0.618	0.000
T52.0 Petroleum products	0.381	0.618	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.381	0.618	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.381	0.618	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.381	0.618	0.000
T53.5 Chlorofluorocarbons	0.381	0.618	0.000
T53.4 Dichloromethane	0.381	0.618	0.000
T53.3 Tetrachloroethylene	0.381	0.618	0.000
T53.2 Trichloroethylene	0.381	0.618	0.000
T53.1 Chloroform	0.381	0.618	0.000
T53.0 Carbon tetrachloride	0.381	0.618	0.000
T57.9 Inorganic substance, unspecified	0.381	0.618	0.000
T57.8 Other specified inorganic substances	0.381	0.618	0.000
T57.3 Hydrogen cyanide	0.381	0.618	0.000
T57.2 Manganese and its compounds	0.381	0.618	0.000
T57.1 Phosphorus and its compounds	0.381	0.618	0.000
T57.0 Arsenic and its compounds	0.381	0.618	0.000
T60.9 Pesticide, unspecified	0.381	0.618	0.000
T60.8 Other pesticides	0.381	0.618	0.000
T60.4 Rodenticides	0.381	0.618	0.000
T60.3 Herbicides and fungicides	0.381	0.618	0.000
T60.2 Other insecticides	0.381	0.618	0.000
T60.1 Halogenated insecticides	0.381	0.618	0.000
T60.0 Organophosphate and carbamate insecticides	0.381	0.618	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.381	0.619	0.000
T54.2 Corrosive acids and acid-like substances	0.381	0.619	0.000
T54.1 Other corrosive organic compounds	0.381	0.619	0.000
T54.0 Phenol and phenol homologues	0.381	0.619	0.000
T43.6 Psychostimulants with abuse potential	0.381	0.619	0.000
T74 Maltreatment syndromes	0.381	0.619	0.000
T73 Effects of other deprivation	0.381	0.619	0.000
T69 Other effects of reduced temperature	0.381	0.619	0.000
T67 Effects of heat and light	0.381	0.619	0.000
T54.9 Corrosive substance, unspecified	0.381	0.619	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.380	0.620	0.000
S38.2 Traumatic amputation of external genital organs	0.380	0.620	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.380	0.620	0.000
S38.0 Crushing injury of external genital organs	0.380	0.620	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.380	0.620	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.380	0.620	0.000
S91.0 Open wound of ankle	0.380	0.620	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.378	0.621	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.376	0.623	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.376	0.624	0.000
T17.3 Foreign body in larynx	0.373	0.627	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.372	0.628	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.371	0.628	0.000
S20-S29 Injuries to the thorax	0.369	0.631	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.368	0.631	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.368	0.632	0.000
S05.1 Contusion of eyeball and orbital tissues	0.367	0.633	0.000
T59.9 Gases, fumes and vapours, unspecified	0.367	0.633	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.366	0.633	0.000
S98.3 Traumatic amputation of other parts of foot	0.366	0.633	0.000
S98.2 Traumatic amputation of two or more toes	0.366	0.633	0.000
S98.0 Traumatic amputation of foot at ankle level	0.366	0.633	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.366	0.634	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.366	0.634	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.366	0.634	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.366	0.634	0.000
T09.1 Open wound of trunk, level unspecified	0.366	0.634	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.366	0.634	0.000
S01.0 Open wound of scalp	0.366	0.634	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.364	0.636	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.364	0.636	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.364	0.636	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.364	0.636	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.364	0.636	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.364	0.636	0.000
S17 Crushing injury of neck	0.363	0.637	0.000
S15 Injury of blood vessels at neck level	0.363	0.637	0.000
S18 Traumatic amputation at neck level	0.363	0.637	0.000
S16 Injury of muscle and tendon at neck level	0.363	0.637	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.362	0.638	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.362	0.638	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.362	0.638	0.000
S34.4 Injury of lumbosacral plexus	0.362	0.638	0.000
S34.3 Injury of cauda equina	0.362	0.638	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.362	0.638	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.361	0.638	0.000
T41.2 Other and unspecified general anaesthetics	0.360	0.640	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.360	0.640	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.359	0.641	0.000
S91.7 Multiple open wounds of ankle and foot	0.359	0.641	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.358	0.641	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.358	0.641	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.358	0.641	0.000
S35.5 Injury of iliac blood vessels	0.358	0.641	0.000
S35.4 Injury of renal blood vessels	0.358	0.641	0.000
S35.3 Injury of portal or splenic vein	0.358	0.641	0.000
S35.1 Injury of inferior vena cava	0.358	0.641	0.000
S35.0 Injury of abdominal aorta	0.358	0.641	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.359	0.641	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.359	0.641	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.359	0.641	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.359	0.641	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.359	0.641	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.359	0.641	0.000
T44.0 Anticholinesterase agents	0.359	0.641	0.000
S92.41 Fracture of great toe (open)	0.358	0.642	0.000
S92.11 Fracture of talus (open)	0.357	0.643	0.000
T70 Effects of air pressure and water pressure	0.357	0.643	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.357	0.643	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.356	0.644	0.000
S02.6 Fracture of mandible	0.355	0.644	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.356	0.644	0.000
S40-S49 Injuries to the shoulder and upper arm	0.356	0.644	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.356	0.644	0.000
S02.11 Fracture of base of skull (open)	0.354	0.646	0.000
S19 Other and unspecified injuries of neck	0.353	0.647	0.000
T65.8 Toxic effect of other specified substances	0.350	0.650	0.000
T65.6 Paints and dyes, not elsewhere classified	0.350	0.650	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.350	0.650	0.000
T65.4 Carbon disulphide	0.350	0.650	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.350	0.650	0.000
T65.2 Tobacco and nicotine	0.350	0.650	0.000
T65.1 Strychnine and its salts	0.350	0.650	0.000
T65.0 Cyanides	0.350	0.650	0.000
S92.40 Fracture of great toe (closed)	0.350	0.650	0.000
S92.71 Multiple fractures of foot (open)	0.349	0.650	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.349	0.651	0.000
S10.1 Other and unspecified superficial injuries of throat	0.349	0.651	0.000
T01.3 Open wounds involving multiple regions of lower limb(s)	0.348	0.652	0.000
S05.9 Injury of eye and orbit, part unspecified	0.347	0.652	0.000
S09.1 Injury of muscle and tendon of head	0.347	0.653	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.347	0.653	0.000
S31.2 Open wound of penis	0.347	0.653	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.347	0.653	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.346	0.654	0.000
S01.5 Open wound of lip and oral cavity	0.346	0.654	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.345	0.655	0.000
S93.40 Sprain of unspecified ligament of ankle	0.345	0.655	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.344	0.656	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.344	0.656	0.000
T14 Injury of unspecified body region	0.342	0.657	0.000
T48.5 Anti-common-cold drugs	0.341	0.658	0.000
S98.1 Traumatic amputation of one toe	0.341	0.659	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.339	0.661	0.000
T15.0 Foreign body in cornea	0.339	0.661	0.000
S12.9 Fracture of neck, part unspecified	0.338	0.662	0.000
T36.8 Other systemic antibiotics	0.338	0.662	0.000
T63.4 Venom of other arthropods	0.336	0.664	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.335	0.664	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.335	0.664	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations