TreeWAS – Variant ID: rs11104268

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E70-E90 Metabolic disorders	0.000	0.829	0.171
E86 Volume depletion	0.000	0.829	0.171
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.832	0.168
E87.6 Hypokalaemia	0.000	0.836	0.164
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.843	0.157
E87.0 Hyperosmolality and hypernatraemia	0.000	0.849	0.151
E87.5 Hyperkalaemia	0.000	0.852	0.148
E89.0 Postprocedural hypothyroidism	0.000	0.854	0.146
E88 Other metabolic disorders	0.000	0.855	0.145
E11.4 With neurological complications	0.000	0.860	0.139
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.862	0.138
E11 Non-insulin-dependent diabetes mellitus	0.000	0.864	0.136
E10-E14 Diabetes mellitus	0.000	0.868	0.132
E73 Lactose intolerance	0.000	0.870	0.130
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.873	0.127
E85 Amyloidosis	0.000	0.876	0.124
E84 Cystic fibrosis	0.000	0.877	0.123
E79 Disorders of purine and pyrimidine metabolism	0.000	0.877	0.123
E77 Disorders of glycoprotein metabolism	0.000	0.877	0.123
E76 Disorders of glycosaminoglycan metabolism	0.000	0.877	0.123
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.877	0.123
E72 Other disorders of amino-acid metabolism	0.000	0.877	0.123
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.877	0.123
E70 Disorders of aromatic amino-acid metabolism	0.000	0.877	0.123
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.877	0.123
E11.2 With renal complications	0.000	0.878	0.122
E89.3 Postprocedural hypopituitarism	0.000	0.878	0.121
E89.2 Postprocedural hypoparathyroidism	0.000	0.879	0.121
E87.4 Mixed disorder of acid-base balance	0.000	0.879	0.120
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.882	0.118
E20-E35 Disorders of other endocrine glands	0.000	0.882	0.118
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.883	0.117
E40-E46 Malnutrition	0.000	0.883	0.117
E11.5 With peripheral circulatory complications	0.000	0.884	0.116
E11.3 With ophthalmic complications	0.000	0.884	0.116
E87.7 Fluid overload	0.000	0.886	0.114
E74 Other disorders of carbohydrate metabolism	0.000	0.886	0.113
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.887	0.113
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.887	0.113
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.887	0.113
E89.5 Postprocedural testicular hypofunction	0.000	0.887	0.113
E89.1 Postprocedural hypoinsulinaemia	0.000	0.887	0.113
E83 Disorders of mineral metabolism	0.000	0.889	0.111
E87.2 Acidosis	0.000	0.890	0.110
E23 Hypofunction and other disorders of pituitary gland	0.000	0.892	0.108
E50-E64 Other nutritional deficiencies	0.000	0.893	0.107
E88.9 Metabolic disorder, unspecified	0.000	0.896	0.104
E88.8 Other specified metabolic disorders	0.000	0.896	0.104
E88.3 Tumour lysis syndrome	0.000	0.896	0.104
E88.2 Lipomatosis, not elsewhere classified	0.000	0.896	0.104
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.896	0.104
E46 Unspecified protein-energy malnutrition	0.000	0.899	0.101
E73.9 Lactose intolerance, unspecified	0.000	0.900	0.100
E11.0 With coma	0.000	0.900	0.100
E65-E68 Obesity and other hyperalimentation	0.000	0.902	0.098
E11.7 With multiple complications	0.000	0.903	0.097
E23.0 Hypopituitarism	0.000	0.904	0.096
E27 Other disorders of adrenal gland	0.000	0.905	0.095
E12 Malnutrition-related diabetes mellitus	0.000	0.905	0.095
E89.4 Postprocedural ovarian failure	0.000	0.905	0.094
E73.8 Other lactose intolerance	0.000	0.907	0.093
E73.1 Secondary lactase deficiency	0.000	0.907	0.093
E73.0 Congenital lactase deficiency	0.000	0.907	0.093
E13 Other specified diabetes mellitus	0.000	0.908	0.092
E11.1 With ketoacidosis	0.000	0.908	0.092
E22 Hyperfunction of pituitary gland	0.000	0.909	0.091
E23.2 Diabetes insipidus	0.000	0.909	0.091
E85.4 Organ-limited amyloidosis	0.000	0.909	0.091
E83.1 Disorders of iron metabolism	0.000	0.910	0.090
E83.4 Disorders of magnesium metabolism	0.000	0.910	0.089
E85.9 Amyloidosis, unspecified	0.000	0.911	0.089
E85.8 Other amyloidosis	0.000	0.911	0.089
E85.3 Secondary systemic amyloidosis	0.000	0.911	0.089
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.911	0.089
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.911	0.089
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.911	0.089
E87.3 Alkalosis	0.000	0.911	0.089
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.912	0.088
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.912	0.088
E70.3 Albinism	0.000	0.912	0.088
E70.2 Disorders of tyrosine metabolism	0.000	0.912	0.088
E70.1 Other hyperphenylalaninaemias	0.000	0.912	0.088
E70.0 Classical phenylketonuria	0.000	0.912	0.088
E71.3 Disorders of fatty-acid metabolism	0.000	0.912	0.088
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.912	0.088
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.912	0.088
E71.0 Maple-syrup-urine disease	0.000	0.912	0.088
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.912	0.088
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.912	0.088
E72.5 Disorders of glycine metabolism	0.000	0.912	0.088
E72.4 Disorders of ornithine metabolism	0.000	0.912	0.088
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.912	0.088
E72.2 Disorders of urea cycle metabolism	0.000	0.912	0.088
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.912	0.088
E72.0 Disorders of amino-acid transport	0.000	0.912	0.088
E75.6 Lipid storage disorder, unspecified	0.000	0.912	0.088
E75.5 Other lipid storage disorders	0.000	0.912	0.088
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.912	0.088
E75.3 Sphingolipidosis, unspecified	0.000	0.912	0.088
E75.2 Other sphingolipidosis	0.000	0.912	0.088
E75.1 Other gangliosidosis	0.000	0.912	0.088
E75.0 GM2 gangliosidosis	0.000	0.912	0.088
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.912	0.088
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.912	0.088
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.912	0.088
E76.2 Other mucopolysaccharidoses	0.000	0.912	0.088
E76.1 Mucopolysaccharidosis, type II	0.000	0.912	0.088
E76.0 Mucopolysaccharidosis, type I	0.000	0.912	0.088
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.912	0.088
E77.8 Other disorders of glycoprotein metabolism	0.000	0.912	0.088
E77.1 Defects in glycoprotein degradation	0.000	0.912	0.088
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.912	0.088
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.912	0.088
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.912	0.088
E79.1 Lesch-Nyhan syndrome	0.000	0.912	0.088
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.912	0.088
E84.9 Cystic fibrosis, unspecified	0.000	0.912	0.088
E84.8 Cystic fibrosis with other manifestations	0.000	0.912	0.088
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.912	0.088
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.912	0.088
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.912	0.088
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.912	0.087
E29 Testicular dysfunction	0.000	0.913	0.087
E28 Ovarian dysfunction	0.000	0.914	0.086
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.915	0.084
E32 Diseases of thymus	0.000	0.915	0.084
E31 Polyglandular dysfunction	0.000	0.915	0.084
E30 Disorders of puberty, not elsewhere classified	0.000	0.915	0.084
E25 Adrenogenital disorders	0.000	0.915	0.084
E20 Hypoparathyroidism	0.000	0.915	0.084
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.916	0.084
E80.6 Other disorders of bilirubin metabolism	0.000	0.916	0.084
E80.5 Crigler-Najjar syndrome	0.000	0.916	0.084
E80.3 Defects of catalase and peroxydase	0.000	0.916	0.084
E80.2 Other porphyria	0.000	0.916	0.084
E80.1 Porphyria cutanea tarda	0.000	0.916	0.084
E80.0 Hereditary erythropoietic porphyria	0.000	0.916	0.084
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.916	0.084
E45 Retarded development following protein-energy malnutrition	0.000	0.916	0.084
E43 Unspecified severe protein-energy malnutrition	0.000	0.916	0.084
E42 Marasmic kwashiorkor	0.000	0.916	0.084
E41 Nutritional marasmus	0.000	0.916	0.084
E40 Kwashiorkor	0.000	0.916	0.084
E55 Vitamin D deficiency	0.000	0.916	0.084
E26 Hyperaldosteronism	0.000	0.918	0.082
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.918	0.081
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.918	0.081
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.918	0.081
E74.2 Disorders of galactose metabolism	0.000	0.918	0.081
E74.1 Disorders of fructose metabolism	0.000	0.918	0.081
E74.0 Glycogen storage disease	0.000	0.918	0.081
E27.1 Primary adrenocortical insufficiency	0.000	0.919	0.081
E11.8 With unspecified complications	0.000	0.920	0.080
E11.6 With other specified complications	0.000	0.920	0.080
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.920	0.080
E83.8 Other disorders of mineral metabolism	0.000	0.920	0.080
E83.2 Disorders of zinc metabolism	0.000	0.920	0.080
E83.0 Disorders of copper metabolism	0.000	0.920	0.080
E61 Deficiency of other nutrient elements	0.000	0.921	0.079
E80.4 Gilbert's syndrome	0.000	0.921	0.079
E34 Other endocrine disorders	0.000	0.922	0.078
E65 Localised adiposity	0.000	0.922	0.078
E23.7 Disorder of pituitary gland, unspecified	0.000	0.922	0.078
E23.6 Other disorders of pituitary gland	0.000	0.922	0.078
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.922	0.078
E23.1 Drug-induced hypopituitarism	0.000	0.922	0.078
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.923	0.077
E63 Other nutritional deficiencies	0.000	0.923	0.077
E56 Other vitamin deficiencies	0.000	0.923	0.077
E51 Thiamine deficiency	0.000	0.923	0.077
E50 Vitamin A deficiency	0.000	0.923	0.077
E60 Dietary zinc deficiency	0.000	0.923	0.077
E59 Dietary selenium deficiency	0.000	0.923	0.077
E58 Dietary calcium deficiency	0.000	0.923	0.077
E54 Ascorbic acid deficiency	0.000	0.923	0.077
E52 Niacin deficiency [pellagra]	0.000	0.923	0.077
E53 Deficiency of other B group vitamins	0.000	0.923	0.077
E83.3 Disorders of phosphorus metabolism	0.000	0.924	0.076
E22.0 Acromegaly and pituitary gigantism	0.000	0.926	0.073
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.928	0.072
E27.8 Other specified disorders of adrenal gland	0.000	0.928	0.072
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.929	0.071
E67 Other hyperalimentation	0.000	0.930	0.070
E68 Sequelae of hyperalimentation	0.000	0.930	0.070
E27.5 Adrenomedullary hyperfunction	0.000	0.932	0.068
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.932	0.068
E27.2 Addisonian crisis	0.000	0.932	0.068
E27.0 Other adrenocortical overactivity	0.000	0.932	0.068
E12.9 Without complications	0.000	0.932	0.068
E12.8 With unspecified complications	0.000	0.932	0.068
E12.7 With multiple complications	0.000	0.932	0.068
E12.6 With other specified complications	0.000	0.932	0.068
E12.5 With peripheral circulatory complications	0.000	0.932	0.068
E12.4 With neurological complications	0.000	0.932	0.068
E12.3 With ophthalmic complications	0.000	0.932	0.068
E12.2 With renal complications	0.000	0.932	0.068
E12.1 With ketoacidosis	0.000	0.932	0.068
E12.0 With coma	0.000	0.932	0.068
E55.9 Vitamin D deficiency, unspecified	0.000	0.933	0.067
E13.8 With unspecified complications	0.000	0.933	0.066
E13.7 With multiple complications	0.000	0.933	0.066
E13.6 With other specified complications	0.000	0.933	0.066
E13.5 With peripheral circulatory complications	0.000	0.933	0.066
E13.4 With neurological complications	0.000	0.933	0.066
E13.3 With ophthalmic complications	0.000	0.933	0.066
E13.2 With renal complications	0.000	0.933	0.066
E13.1 With ketoacidosis	0.000	0.933	0.066
E13.0 With coma	0.000	0.933	0.066
E24 Cushing's syndrome	0.000	0.934	0.066
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.934	0.066
E22.8 Other hyperfunction of pituitary gland	0.000	0.934	0.066
E27.9 Disorder of adrenal gland, unspecified	0.000	0.935	0.065
E29.1 Testicular hypofunction	0.000	0.935	0.065
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.935	0.064
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.936	0.064
E13.9 Without complications	0.000	0.936	0.064
E28.2 Polycystic ovarian syndrome	0.000	0.937	0.063
E15 Nondiabetic hypoglycaemic coma	0.000	0.937	0.063
E10 Insulin-dependent diabetes mellitus	0.000	0.937	0.063
E29.9 Testicular dysfunction, unspecified	0.000	0.938	0.062
E29.8 Other testicular dysfunction	0.000	0.938	0.062
E29.0 Testicular hyperfunction	0.000	0.938	0.062
E28.9 Ovarian dysfunction, unspecified	0.000	0.938	0.062
E28.8 Other ovarian dysfunction	0.000	0.938	0.062
E28.3 Primary ovarian failure	0.000	0.938	0.062
E28.1 Androgen excess	0.000	0.938	0.062
E28.0 Oestrogen excess	0.000	0.938	0.062
E20.9 Hypoparathyroidism, unspecified	0.000	0.939	0.061
E20.8 Other hypoparathyroidism	0.000	0.939	0.061
E20.1 Pseudohypoparathyroidism	0.000	0.939	0.061
E20.0 Idiopathic hypoparathyroidism	0.000	0.939	0.061
E25.9 Adrenogenital disorder, unspecified	0.000	0.939	0.061
E25.8 Other adrenogenital disorders	0.000	0.939	0.061
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.939	0.061
E30.9 Disorder of puberty, unspecified	0.000	0.939	0.061
E30.8 Other disorders of puberty	0.000	0.939	0.061
E30.1 Precocious puberty	0.000	0.939	0.061
E30.0 Delayed puberty	0.000	0.939	0.061
E31.9 Polyglandular dysfunction, unspecified	0.000	0.939	0.061
E31.8 Other polyglandular dysfunction	0.000	0.939	0.061
E31.1 Polyglandular hyperfunction	0.000	0.939	0.061
E31.0 Autoimmune polyglandular failure	0.000	0.939	0.061
E32.9 Disease of thymus, unspecified	0.000	0.939	0.061
E32.8 Other diseases of thymus	0.000	0.939	0.061
E32.1 Abscess of thymus	0.000	0.939	0.061
E32.0 Persistent hyperplasia of thymus	0.000	0.939	0.061
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.939	0.061
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.939	0.061
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.939	0.061
E44.1 Mild protein-energy malnutrition	0.000	0.940	0.060
E44.0 Moderate protein-energy malnutrition	0.000	0.940	0.060
E55.0 Rickets, active	0.000	0.940	0.060
E26.9 Hyperaldosteronism, unspecified	0.000	0.941	0.059
E26.8 Other hyperaldosteronism	0.000	0.941	0.059
E26.1 Secondary hyperaldosteronism	0.000	0.941	0.059
E61.1 Iron deficiency	0.000	0.941	0.058
E66 Obesity	0.000	0.942	0.058
E14 Unspecified diabetes mellitus	0.000	0.942	0.058
E22.1 Hyperprolactinaemia	0.000	0.943	0.057
E61.9 Deficiency of nutrient element, unspecified	0.000	0.943	0.057
E61.8 Deficiency of other specified nutrient elements	0.000	0.943	0.057
E61.7 Deficiency of multiple nutrient elements	0.000	0.943	0.057
E61.6 Vanadium deficiency	0.000	0.943	0.057
E61.5 Molybdenum deficiency	0.000	0.943	0.057
E61.4 Chromium deficiency	0.000	0.943	0.057
E61.3 Manganese deficiency	0.000	0.943	0.057
E61.2 Magnesium deficiency	0.000	0.943	0.057
E61.0 Copper deficiency	0.000	0.943	0.057
E34.8 Other specified endocrine disorders	0.000	0.944	0.056
E34.5 Androgen resistance syndrome	0.000	0.944	0.056
E34.4 Constitutional tall stature	0.000	0.944	0.056
E34.3 Short stature, not elsewhere classified	0.000	0.944	0.056
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.944	0.056
E34.1 Other hypersecretion of intestinal hormones	0.000	0.944	0.056
E34.0 Carcinoid syndrome	0.000	0.944	0.056
E26.0 Primary hyperaldosteronism	0.000	0.944	0.056
E50.9 Vitamin A deficiency, unspecified	0.000	0.944	0.055
E50.8 Other manifestations of vitamin A deficiency	0.000	0.944	0.055
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.944	0.055
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.944	0.055
E50.5 Vitamin A deficiency with night blindness	0.000	0.944	0.055
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.944	0.055
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.944	0.055
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.944	0.055
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.944	0.055
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.944	0.055
E51.9 Thiamine deficiency, unspecified	0.000	0.944	0.055
E51.8 Other manifestations of thiamine deficiency	0.000	0.944	0.055
E51.2 Wernicke's encephalopathy	0.000	0.944	0.055
E51.1 Beriberi	0.000	0.944	0.055
E56.9 Vitamin deficiency, unspecified	0.000	0.944	0.055
E56.8 Deficiency of other vitamins	0.000	0.944	0.055
E56.1 Deficiency of vitamin K	0.000	0.944	0.055
E56.0 Deficiency of vitamin E	0.000	0.944	0.055
E63.9 Nutritional deficiency, unspecified	0.000	0.944	0.055
E63.8 Other specified nutritional deficiencies	0.000	0.944	0.055
E63.1 Imbalance of constituents of food intake	0.000	0.944	0.055
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.944	0.055
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.944	0.055
E64.8 Sequelae of other nutritional deficiencies	0.000	0.944	0.055
E64.3 Sequelae of rickets	0.000	0.944	0.055
E64.2 Sequelae of vitamin C deficiency	0.000	0.944	0.055
E64.1 Sequelae of vitamin A deficiency	0.000	0.944	0.055
E64.0 Sequelae of protein-energy malnutrition	0.000	0.944	0.055
E53.9 Vitamin B deficiency, unspecified	0.000	0.945	0.055
E53.1 Pyridoxine deficiency	0.000	0.945	0.055
E53.0 Riboflavin deficiency	0.000	0.945	0.055
E53.8 Deficiency of other specified B group vitamins	0.000	0.945	0.055
E10.5 With peripheral circulatory complications	0.000	0.948	0.052
E16 Other disorders of pancreatic internal secretion	0.000	0.949	0.051
E10.1 With ketoacidosis	0.000	0.949	0.051
E67.8 Other specified hyperalimentation	0.000	0.949	0.051
E67.3 Hypervitaminosis D	0.000	0.949	0.051
E67.2 Megavitamin-B6 syndrome	0.000	0.949	0.051
E67.1 Hypercarotenaemia	0.000	0.949	0.051
E67.0 Hypervitaminosis A	0.000	0.949	0.051
E34.9 Endocrine disorder, unspecified	0.000	0.950	0.050
E24.8 Other Cushing's syndrome	0.000	0.952	0.048
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.952	0.048
E24.3 Ectopic ACTH syndrome	0.000	0.952	0.048
E24.1 Nelson's syndrome	0.000	0.952	0.048
E24.0 Pituitary-dependent Cushing's disease	0.000	0.952	0.048
E66.9 Obesity, unspecified	0.000	0.953	0.047
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.954	0.046
E21.4 Other specified disorders of parathyroid gland	0.000	0.954	0.046
E21.2 Other hyperparathyroidism	0.000	0.954	0.046
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.954	0.046
E10.4 With neurological complications	0.000	0.954	0.046
E10.8 With unspecified complications	0.000	0.955	0.045
E10.7 With multiple complications	0.000	0.955	0.045
E10.6 With other specified complications	0.000	0.955	0.045
E14.3 With ophthalmic complications	0.000	0.956	0.044
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.958	0.042
E66.1 Drug-induced obesity	0.000	0.958	0.042
E14.8 With unspecified complications	0.000	0.958	0.042
E14.7 With multiple complications	0.000	0.958	0.042
E14.5 With peripheral circulatory complications	0.000	0.958	0.042
E14.4 With neurological complications	0.000	0.958	0.042
E14.2 Withrenal complications	0.000	0.958	0.042
E14.1 With ketoacidosis	0.000	0.958	0.042
E14.0 With coma	0.000	0.958	0.042
E24.9 Cushing's syndrome, unspecified	0.000	0.959	0.041
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.959	0.041
E21.3 Hyperparathyroidism, unspecified	0.000	0.960	0.040
E10.2 With renal complications	0.000	0.960	0.040
E24.2 Drug-induced Cushing's syndrome	0.000	0.961	0.039
E10.3 With ophthalmic complications	0.000	0.961	0.039
E10.0 With coma	0.000	0.961	0.038
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.962	0.038
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.963	0.037
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.963	0.037
E16.4 Abnormal secretion of gastrin	0.000	0.963	0.037
E16.3 Increased secretion of glucagon	0.000	0.963	0.037
E16.1 Other hypoglycaemia	0.000	0.963	0.037
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.963	0.037
E21.0 Primary hyperparathyroidism	0.000	0.964	0.036
E78.2 Mixed hyperlipidaemia	0.000	0.966	0.034
E66.8 Other obesity	0.000	0.966	0.034
E14.6 With other specified complications	0.000	0.966	0.033
R26 Abnormalities of gait and mobility	0.000	0.970	0.030
E78.6 Lipoprotein deficiency	0.000	0.970	0.029
E78.3 Hyperchylomicronaemia	0.000	0.970	0.029
E66.0 Obesity due to excess calories	0.000	0.971	0.029
E83.5 Disorders of calcium metabolism	0.000	0.972	0.028
E78.8 Other disorders of lipoprotein metabolism	0.000	0.973	0.027
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.973	0.027
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.974	0.026
E78.4 Other hyperlipidaemia	0.000	0.974	0.026
E78.1 Pure hyperglyceridaemia	0.000	0.974	0.026
E16.2 Hypoglycaemia, unspecified	0.000	0.975	0.025
E00-E07 Disorders of thyroid gland	0.000	0.975	0.025
R26.0 Ataxic gait	0.000	0.976	0.024
R26.1 Paralytic gait	0.000	0.978	0.022
R26.3 Immobility	0.000	0.979	0.021
E78.5 Hyperlipidaemia, unspecified	0.000	0.980	0.020
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.982	0.018
E00 Congenital iodine-deficiency syndrome	0.000	0.982	0.018
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.982	0.018
E14.9 Without complications	0.000	0.982	0.018
E07 Other disorders of thyroid	0.000	0.982	0.018
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.986	0.014
E06 Thyroiditis	0.000	0.986	0.014
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.987	0.013
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.987	0.013
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.987	0.013
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.987	0.013
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.987	0.013
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.987	0.013
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.987	0.013
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.987	0.013
E07.8 Other specified disorders of thyroid	0.000	0.987	0.013
E07.1 Dyshormogenetic goitre	0.000	0.987	0.013
E07.0 Hypersecretion of calcitonin	0.000	0.987	0.013
E07.9 Disorder of thyroid, unspecified	0.000	0.987	0.013
E03 Other hypothyroidism	0.000	0.988	0.012
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.988	0.012
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.989	0.011
R25.2 Cramp and spasm	0.000	0.989	0.011
E10.9 Without complications	0.000	0.989	0.011
E05.8 Other thyrotoxicosis	0.000	0.990	0.010
E05.5 Thyroid crisis or storm	0.000	0.990	0.010
E05.4 Thyrotoxicosis factitia	0.000	0.990	0.010
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.990	0.010
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.990	0.010
R25 Abnormal involuntary movements	0.000	0.990	0.010
E06.5 Other chronic thyroiditis	0.000	0.990	0.010
E06.4 Drug-induced thyroiditis	0.000	0.990	0.010
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.990	0.010
E06.1 Subacute thyroiditis	0.000	0.990	0.010
E06.0 Acute thyroiditis	0.000	0.990	0.010
E03.8 Other specified hypothyroidism	0.000	0.991	0.009
E06.9 Thyroiditis, unspecified	0.000	0.991	0.009
E03.5 Myxoedema coma	0.000	0.991	0.009
E03.4 Atrophy of thyroid (acquired)	0.000	0.991	0.009
E03.3 Postinfectious hypothyroidism	0.000	0.991	0.009
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.991	0.009
E03.1 Congenital hypothyroidism without goitre	0.000	0.991	0.009
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.991	0.009
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.991	0.008
E05.9 Thyrotoxicosis, unspecified	0.000	0.992	0.008
R25.3 Fasciculation	0.000	0.992	0.008
R27 Other lack of coordination	0.000	0.992	0.008
R25.0 Abnormal head movements	0.000	0.992	0.007
E06.3 Autoimmune thyroiditis	0.000	0.993	0.007
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.993	0.007
E78.0 Pure hypercholesterolaemia	0.000	0.993	0.007
E04 Other non-toxic goitre	0.000	0.993	0.007
S09.9 Unspecified injury of head	0.007	0.993	0.000
E11.9 Without complications	0.000	0.994	0.006
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.994	0.006
R27.0 Ataxia, unspecified	0.000	0.995	0.005
R29.4 Clicking hip	0.000	0.995	0.005
R29.3 Abnormal posture	0.000	0.995	0.005
R29.2 Abnormal reflex	0.000	0.995	0.005
R29.1 Meningismus	0.000	0.995	0.005
R29.0 Tetany	0.000	0.995	0.005
R27.8 Other and unspecified lack of coordination	0.000	0.995	0.005
E04.8 Other specified non-toxic goitre	0.000	0.995	0.005
E04.0 Non-toxic diffuse goitre	0.000	0.995	0.005
E04.9 Non-toxic goitre, unspecified	0.000	0.995	0.005
R29.6 Tendency to fall, not elsewhere classified	0.000	0.995	0.005
I95.1 Orthostatic hypotension	0.000	0.995	0.005
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.005	0.995	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
H54.4 Blindness, one eye	0.004	0.996	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.996	0.004
R25.1 Tremor, unspecified	0.000	0.996	0.004
Z36 Antenatal screening	0.004	0.996	0.000
G20 Parkinson's disease	0.004	0.996	0.000
H33.0 Retinal detachment with retinal break	0.000	0.996	0.004
Z36.8 Other antenatal screening	0.004	0.996	0.000
K62.8 Other specified diseases of anus and rectum	0.004	0.996	0.000
Z36.9 Antenatal screening, unspecified	0.004	0.996	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.003	0.996	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.003	0.997	0.000
N87.1 Moderate cervical dysplasia	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.003	0.997	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.003	0.997	0.000
N87.0 Mild cervical dysplasia	0.003	0.997	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.003	0.997	0.000
Z36.5 Antenatal screening for isoimmunisation	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
N87 Dysplasia of cervix uteri	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.003	0.997	0.000
N86 Erosion and ectropion of cervix uteri	0.003	0.997	0.000
H81.0 Meniere's disease	0.000	0.997	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.997	0.003
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
S09 Other and unspecified injuries of head	0.003	0.997	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.003	0.997	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.003	0.997	0.000
M18 Arthrosis of first carpometacarpal joint	0.003	0.997	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.001	0.997	0.002
C92 Myeloid leukaemia	0.003	0.997	0.000
L89.1 Stage II decubitus ulcer	0.000	0.997	0.003
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
H81 Disorders of vestibular function	0.000	0.997	0.003
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.002
M89.9 Disorder of bone, unspecified	0.002	0.997	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.002	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
H81.2 Vestibular neuronitis	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
S09.7 Multiple injuries of head	0.002	0.998	0.000
S09.2 Traumatic rupture of ear drum	0.002	0.998	0.000
S09.1 Injury of muscle and tendon of head	0.002	0.998	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations