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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111448563
log Bayes Factor = 16.2077
Chromosome 4   position 136,538,658  (GRCh37) Explore rs111448563 on Ensembl!
Variant rs111448563 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N17-N19 Renal failure
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
M45-M49 Spondylopathies
0.995 0.005 0.000
I20-I25 Ischaemic heart diseases
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
M54 Dorsalgia
0.989 0.011 0.000
I50 Heart failure
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
K80 Cholelithiasis
0.983 0.017 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.979 0.021 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.979 0.021 0.000
Chapter XI Diseases of the digestive system
0.978 0.022 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.978 0.022 0.000
N17 Acute renal failure
0.974 0.026 0.000
M06 Other rheumatoid arthritis
0.971 0.029 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.970 0.030 0.000
I50.0 Congestive heart failure
0.970 0.030 0.000
M54.5 Low back pain
0.966 0.034 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.966 0.034 0.000
I25 Chronic ischaemic heart disease
0.964 0.036 0.000
I49 Other cardiac arrhythmias
0.961 0.039 0.000
N20-N23 Urolithiasis
0.959 0.041 0.000
N17.9 Acute renal failure, unspecified
0.958 0.042 0.000
M47 Spondylosis
0.957 0.043 0.000
E70-E90 Metabolic disorders
0.957 0.043 0.000
M06.9 Rheumatoid arthritis, unspecified
0.956 0.044 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.955 0.045 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.947 0.053 0.000
N18 Chronic renal failure
0.944 0.056 0.000
I21 Acute myocardial infarction
0.942 0.058 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.942 0.058 0.000
L82 Seborrhoeic keratosis
0.942 0.058 0.000
E86 Volume depletion
0.933 0.067 0.000
N60-N64 Disorders of breast
0.932 0.068 0.000
I35 Nonrheumatic aortic valve disorders
0.930 0.070 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.927 0.073 0.000
Chapter X Diseases of the respiratory system
0.925 0.075 0.000
M54.9 Dorsalgia, unspecified
0.923 0.077 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.917 0.083 0.000
Y84.8 Other medical procedures
0.915 0.085 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.915 0.085 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.912 0.088 0.000
M51 Other intervertebral disk disorders
0.912 0.088 0.000
M47.8 Other spondylosis
0.909 0.091 0.000
I50.1 Left ventricular failure
0.905 0.095 0.000
N20 Calculus of kidney and ureter
0.905 0.095 0.000
M48 Other spondylopathies
0.901 0.099 0.000
M54.57 Low back pain (Lumbosacral region)
0.899 0.101 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.894 0.106 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.893 0.107 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.892 0.108 0.000
Chapter XXI Factors influencing health status and contact with health services
0.890 0.110 0.000
N19 Unspecified renal failure
0.889 0.111 0.000
I44 Atrioventricular and left bundle-branch block
0.881 0.119 0.000
M54.56 Low back pain (Lumbar region)
0.880 0.120 0.000
I46 Cardiac arrest
0.880 0.120 0.000
I21.4 Acute subendocardial myocardial infarction
0.879 0.121 0.000
N20.0 Calculus of kidney
0.879 0.121 0.000
M47.86 Other spondylosis (Lumbar region)
0.876 0.124 0.000
Chapter V Mental and behavioural disorders
0.876 0.124 0.000
N18.5 Chronic kidney disease, stage 5
0.868 0.132 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.867 0.133 0.000
L89 Decubitus ulcer
0.867 0.133 0.000
K40-K46 Hernia
0.866 0.134 0.000
N62 Hypertrophy of breast
0.865 0.135 0.000
I42 Cardiomyopathy
0.863 0.137 0.000
Chapter II Neoplasms
0.863 0.137 0.000
N00-N08 Glomerular diseases
0.862 0.138 0.000
I25.1 Atherosclerotic heart disease
0.861 0.139 0.000
K35-K38 Diseases of appendix
0.860 0.140 0.000
J09-J18 Influenza and pneumonia
0.855 0.145 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.850 0.149 0.000
J90-J94 Other diseases of pleura
0.850 0.150 0.000
M46 Other inflammatory spondylopathies
0.850 0.150 0.000
M10 Gout
0.850 0.150 0.000
I24 Other acute ischaemic heart diseases
0.847 0.153 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.847 0.153 0.000
C15-C26 Malignant neoplasms of digestive organs
0.845 0.155 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.843 0.157 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.842 0.158 0.000
M80-M85 Disorders of bone density and structure
0.839 0.161 0.000
E00-E07 Disorders of thyroid gland
0.839 0.161 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.838 0.162 0.000
M45 Ankylosing spondylitis
0.836 0.164 0.000
Chapter I Certain infectious and parasitic diseases
0.835 0.165 0.000
I35.0 Aortic (valve) stenosis
0.834 0.166 0.000
M40-M43 Deforming dorsopathies
0.833 0.167 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.832 0.168 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.829 0.171 0.000
N23 Unspecified renal colic
0.829 0.171 0.000
I22 Subsequent myocardial infarction
0.828 0.172 0.000
N18.0 End-stage renal disease
0.825 0.175 0.000
M47.2 Other spondylosis with radiculopathy
0.821 0.179 0.000
M54.1 Radiculopathy
0.821 0.179 0.000
N99-N99 Other disorders of the genitourinary system
0.820 0.180 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.820 0.180 0.000
I46.9 Cardiac arrest, unspecified
0.817 0.183 0.000
E10-E14 Diabetes mellitus
0.817 0.183 0.000
J95-J99 Other diseases of the respiratory system
0.815 0.185 0.000
I49.5 Sick sinus syndrome
0.812 0.188 0.000
M48.0 Spinal stenosis
0.811 0.189 0.000
L81 Other disorders of pigmentation
0.808 0.192 0.000
I44.7 Left bundle-branch block, unspecified
0.807 0.193 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.806 0.194 0.000
N25-N29 Other disorders of kidney and ureter
0.806 0.194 0.000
C16 Malignant neoplasm of stomach
0.806 0.194 0.000
K35 Acute appendicitis
0.805 0.195 0.000
L50-L54 Urticaria and erythema
0.801 0.199 0.000
K42 Umbilical hernia
0.800 0.199 0.000
I49.0 Ventricular fibrillation and flutter
0.800 0.200 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.796 0.204 0.000
I34 Nonrheumatic mitral valve disorders
0.796 0.204 0.000
T79-T79 Certain early complications of trauma
0.794 0.206 0.000
S40-S49 Injuries to the shoulder and upper arm
0.793 0.207 0.000
M07 Psoriatic and enteropathic arthropathies
0.793 0.207 0.000
Chapter VII Diseases of the eye and adnexa
0.792 0.208 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.792 0.208 0.000
I49.3 Ventricular premature depolarisation
0.791 0.208 0.000
L20-L30 Dermatitis and eczema
0.791 0.209 0.000
J90 Pleural effusion, not elsewhere classified
0.789 0.211 0.000
E20-E35 Disorders of other endocrine glands
0.785 0.215 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
M51.2 Other specified intervertebral disk displacement
0.783 0.216 0.000
M05 Seropositive rheumatoid arthritis
0.783 0.217 0.000
I38 Endocarditis, valve unspecified
0.781 0.219 0.000
Y84.1 Kidney dialysis
0.780 0.220 0.000
C18 Malignant neoplasm of colon
0.780 0.220 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.779 0.221 0.000
L89.1 Stage II decubitus ulcer
0.779 0.221 0.000
Z22 Carrier of infectious disease
0.776 0.224 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.776 0.224 0.000
Chapter VI Diseases of the nervous system
0.776 0.224 0.000
Chapter VIII Diseases of the ear and mastoid process
0.775 0.225 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.773 0.227 0.000
I49.1 Atrial premature depolarisation
0.773 0.227 0.000
I05-I09 Chronic rheumatic heart diseases
0.773 0.227 0.000
M00-M03 Infectious arthropathies
0.773 0.227 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.771 0.229 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.771 0.229 0.000
M65-M68 Disorders of synovium and tendon
0.768 0.232 0.000
Y84.0 Cardiac catheterisation
0.766 0.234 0.000
L83 Acanthosis nigricans
0.765 0.235 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.761 0.239 0.000
I49.9 Cardiac arrhythmia, unspecified
0.761 0.239 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.759 0.241 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.759 0.241 0.000
K43 Ventral hernia
0.757 0.243 0.000
E05.9 Thyrotoxicosis, unspecified
0.757 0.243 0.000
V80-V89 Other land transport accidents
0.756 0.243 0.000
Z49 Care involving dialysis
0.754 0.246 0.000
E40-E46 Malnutrition
0.751 0.249 0.000
M10.9 Gout, unspecified
0.750 0.250 0.000
I47 Paroxysmal tachycardia
0.750 0.250 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.749 0.250 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.749 0.250 0.000
V10-V19 Pedal cyclist injured in transport accident
0.748 0.252 0.000
J18 Pneumonia, organism unspecified
0.748 0.252 0.000
L91 Hypertrophic disorders of skin
0.748 0.252 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.747 0.253 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.746 0.254 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.746 0.254 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.746 0.254 0.000
I35.9 Aortic valve disorder, unspecified
0.743 0.257 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.743 0.257 0.000
L93 Lupus erythematosus
0.743 0.257 0.000
C64-C68 Malignant neoplasms of urinary tract
0.742 0.258 0.000
I24.8 Other forms of acute ischaemic heart disease
0.741 0.259 0.000
I30 Acute pericarditis
0.741 0.259 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.738 0.262 0.000
Z22.3 Carrier of other specified bacterial diseases
0.737 0.263 0.000
H53-H54 Visual disturbances and blindness
0.736 0.264 0.000
N18.9 Chronic renal failure, unspecified
0.735 0.265 0.000
Z87 Personal history of other diseases and conditions
0.734 0.266 0.000
K85 Acute pancreatitis
0.734 0.266 0.000
I25.5 Ischaemic cardiomyopathy
0.733 0.267 0.000
I42.6 Alcoholic cardiomyopathy
0.732 0.268 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.731 0.269 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.730 0.270 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
Y83.4 Other reconstructive surgery
0.728 0.272 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.727 0.273 0.000
I45 Other conduction disorders
0.726 0.274 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.726 0.274 0.000
M06.0 Seronegative rheumatoid arthritis
0.725 0.275 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.724 0.276 0.000
M54.4 Lumbago with sciatica
0.723 0.276 0.000
J98 Other respiratory disorders
0.723 0.277 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.723 0.277 0.000
E10 Insulin-dependent diabetes mellitus
0.723 0.277 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.722 0.278 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.722 0.278 0.000
E83 Disorders of mineral metabolism
0.721 0.279 0.000
I35.1 Aortic (valve) insufficiency
0.721 0.279 0.000
M11 Other crystal arthropathies
0.719 0.281 0.000
Y84.6 Urinary catheterisation
0.719 0.281 0.000
S00-S09 Injuries to the head
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
W20-W49 Exposure to inanimate mechanical forces
0.716 0.284 0.000
N64 Other disorders of breast
0.716 0.284 0.000
Z49.0 Preparatory care for dialysis
0.714 0.286 0.000
M53 Other dorsopathies, not elsewhere classified
0.714 0.286 0.000
M49 Spondylopathies in diseases classified elsewhere
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.713 0.287 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.713 0.287 0.000
B95-B98 Bacterial, viral and other infectious agents
0.713 0.287 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.712 0.288 0.000
F30-F39 Mood [affective] disorders
0.712 0.288 0.000
N63 Unspecified lump in breast
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
Z95.4 Presence of other heart-valve replacement
0.710 0.290 0.000
M54.59 Low back pain (Site unspecified)
0.710 0.290 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
C16.9 Stomach, unspecified
0.710 0.290 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.709 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
S10-S19 Injuries to the neck
0.709 0.291 0.000
M54.8 Other dorsalgia
0.709 0.291 0.000
M54.6 Pain in thoracic spine
0.709 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.291 0.000
M43 Other deforming dorsopathies
0.708 0.292 0.000
N10-N16 Renal tubulo-interstitial diseases
0.707 0.293 0.000
K80.3 Calculus of bile duct with cholangitis
0.705 0.295 0.000
K80.8 Other cholelithiasis
0.705 0.295 0.000
K80.4 Calculus of bile duct with cholecystitis
0.705 0.295 0.000
E87.6 Hypokalaemia
0.704 0.296 0.000
K65-K67 Diseases of peritoneum
0.703 0.297 0.000
L10-L14 Bullous disorders
0.702 0.298 0.000
C77.2 Intra-abdominal lymph nodes
0.701 0.299 0.000
N02 Recurrent and persistent haematuria
0.701 0.299 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.701 0.299 0.000
M54.16 Radiculopathy (Lumbar region)
0.701 0.299 0.000
X60-X84 Intentional self-harm
0.700 0.300 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.699 0.301 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.699 0.301 0.000
N17.8 Other acute renal failure
0.698 0.301 0.000
N17.2 Acute renal failure with medullary necrosis
0.698 0.301 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.698 0.301 0.000
N17.0 Acute renal failure with tubular necrosis
0.698 0.301 0.000
C50-C50 Malignant neoplasm of breast
0.698 0.302 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.698 0.302 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.698 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.302 0.000
M86-M90 Other osteopathies
0.697 0.302 0.000
M84 Disorders of continuity of bone
0.697 0.302 0.000
M06.8 Other specified rheumatoid arthritis
0.696 0.304 0.000
M06.4 Inflammatory polyarthropathy
0.696 0.304 0.000
M06.3 Rheumatoid nodule
0.696 0.304 0.000
M06.2 Rheumatoid bursitis
0.696 0.304 0.000
M06.1 Adult-onset Still's disease
0.696 0.304 0.000
K90-K93 Other diseases of the digestive system
0.696 0.304 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.695 0.305 0.000
N60 Benign mammary dysplasia
0.695 0.305 0.000
L81.4 Other melanin hyperpigmentation
0.695 0.305 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.305 0.000
I42.0 Dilated cardiomyopathy
0.694 0.306 0.000
E06 Thyroiditis
0.694 0.306 0.000
C16.0 Cardia
0.694 0.306 0.000
I78 Diseases of capillaries
0.694 0.306 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
M54.55 Low back pain (Thoracolumbar region)
0.693 0.307 0.000
M54.54 Low back pain-Thoracic
0.693 0.307 0.000
M54.53 Low back pain-Cervicothoracic
0.693 0.307 0.000
M54.52 Low back pain-Cervical
0.693 0.307 0.000
M54.51 Low back pain-Occipit-atl-axl
0.693 0.307 0.000
M54.50 Low back pain (Multiple sites in spine)
0.693 0.307 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.692 0.307 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.692 0.307 0.000
L94 Other localised connective tissue disorders
0.692 0.307 0.000
L87 Transepidermal elimination disorders
0.692 0.307 0.000
L88 Pyoderma gangrenosum
0.692 0.307 0.000
L86 Keratoderma in diseases classified elsewhere
0.692 0.307 0.000
L84 Corns and callosities
0.692 0.307 0.000
L80 Vitiligo
0.692 0.307 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.692 0.308 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.692 0.308 0.000
I25.6 Silent myocardial ischaemia
0.691 0.309 0.000
I25.4 Coronary artery aneurysm
0.691 0.309 0.000
I25.3 Aneurysm of heart
0.691 0.309 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.691 0.309 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.691 0.309 0.000
S90-S99 Injuries to the ankle and foot
0.691 0.309 0.000
S60-S69 Injuries to the wrist and hand
0.689 0.311 0.000
I49.4 Other and unspecified premature depolarisation
0.689 0.311 0.000
I49.2 Junctional premature depolarisation
0.689 0.311 0.000
Z49.1 Extracorporeal dialysis
0.688 0.312 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.688 0.312 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.688 0.312 0.000
M47.82 Other spondylosis (Cervical region)
0.688 0.312 0.000
M47.1 Other spondylosis with myelopathy
0.686 0.313 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.686 0.313 0.000
E88 Other metabolic disorders
0.686 0.314 0.000
E85 Amyloidosis
0.686 0.314 0.000
E84 Cystic fibrosis
0.686 0.314 0.000
E79 Disorders of purine and pyrimidine metabolism
0.686 0.314 0.000
E77 Disorders of glycoprotein metabolism
0.686 0.314 0.000
E76 Disorders of glycosaminoglycan metabolism
0.686 0.314 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.686 0.314 0.000
E74 Other disorders of carbohydrate metabolism
0.686 0.314 0.000
E73 Lactose intolerance
0.686 0.314 0.000
E72 Other disorders of amino-acid metabolism
0.686 0.314 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.686 0.314 0.000
E70 Disorders of aromatic amino-acid metabolism
0.686 0.314 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.686 0.314 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.686 0.314 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.686 0.314 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.686 0.314 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.686 0.314 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.686 0.314 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.686 0.314 0.000
Y84.9 Medical procedure, unspecified
0.685 0.315 0.000
Y84.7 Blood-sampling
0.685 0.315 0.000
Y84.5 Insertion of gastric or duodenal sound
0.685 0.315 0.000
Y84.4 Aspiration of fluid
0.685 0.315 0.000
Y84.3 Shock therapy
0.685 0.315 0.000
S20-S29 Injuries to the thorax
0.684 0.316 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.684 0.316 0.000
Z95.2 Presence of prosthetic heart valve
0.683 0.317 0.000
I49.8 Other specified cardiac arrhythmias
0.683 0.317 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.682 0.318 0.000
E87.0 Hyperosmolality and hypernatraemia
0.681 0.319 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.680 0.320 0.000
N20.2 Calculus of kidney with calculus of ureter
0.680 0.320 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.679 0.321 0.000
C77.3 Axillary and upper limb lymph nodes
0.679 0.321 0.000
N18.2 Chronic kidney disease, stage 2
0.677 0.323 0.000
K45 Other abdominal hernia
0.677 0.323 0.000
N18.8 Other chronic renal failure
0.677 0.323 0.000
N18.1 Chronic kidney disease, stage 1
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
J14 Pneumonia due to Haemophilus influenzae
0.676 0.324 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.675 0.324 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.675 0.324 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.675 0.325 0.000
T87 Complications peculiar to reattachment and amputation
0.675 0.325 0.000
T86 Failure and rejection of transplanted organs and tissues
0.675 0.325 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.675 0.325 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.675 0.325 0.000
J18.1 Lobar pneumonia, unspecified
0.674 0.326 0.000
H53 Visual disturbances
0.673 0.327 0.000
L90 Atrophic disorders of skin
0.673 0.327 0.000
K35.9 Acute appendicitis, unspecified
0.672 0.327 0.000
C16.5 Lesser curvature of stomach, unspecified
0.671 0.329 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.670 0.330 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.670 0.330 0.000
H43-H45 Disorders of vitreous body and globe
0.669 0.331 0.000
M48.06 Spinal stenosis (Lumbar region)
0.668 0.332 0.000
I44.2 Atrioventricular block, complete
0.668 0.332 0.000
N21 Calculus of lower urinary tract
0.668 0.332 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.668 0.332 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.667 0.333 0.000
Y83.9 Surgical procedure, unspecified
0.667 0.333 0.000
I35.8 Other aortic valve disorders
0.667 0.333 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.666 0.334 0.000
M47.89 Other spondylosis (Site unspecified)
0.665 0.334 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.665 0.335 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.335 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.665 0.335 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.665 0.335 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.665 0.335 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.665 0.335 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
T36 Poisoning by systemic antibiotics
0.665 0.335 0.000
E87.7 Fluid overload
0.665 0.335 0.000
T82.1 Mechanical complication of cardiac electronic device
0.662 0.338 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.662 0.338 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.662 0.338 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.662 0.338 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.662 0.338 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.662 0.338 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.662 0.338 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.662 0.338 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.662 0.338 0.000
M47.9 Spondylosis, unspecified
0.661 0.339 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.661 0.339 0.000
L53 Other erythematous conditions
0.661 0.339 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.661 0.339 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.661 0.339 0.000
J92 Pleural plaque
0.661 0.339 0.000
N18.4 Chronic kidney disease, stage 4
0.660 0.340 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.659 0.341 0.000
E50-E64 Other nutritional deficiencies
0.658 0.341 0.000
M48.09 Spinal stenosis (Site unspecified)
0.658 0.341 0.000
I72 Other aneurysm
0.658 0.342 0.000
E10.3 With ophthalmic complications
0.657 0.343 0.000
Z29 Need for other prophylactic measures
0.656 0.344 0.000
T66-T78 Other and unspecified effects of external causes
0.656 0.344 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.656 0.344 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.656 0.344 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.656 0.344 0.000
T82.3 Mechanical complication of other vascular grafts
0.656 0.344 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.656 0.344 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.656 0.344 0.000
M48.02 Spinal stenosis (Cervical region)
0.655 0.345 0.000
F80-F89 Disorders of psychological development
0.655 0.345 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.655 0.345 0.000
J60-J70 Lung diseases due to external agents
0.655 0.345 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.654 0.346 0.000
M51.3 Other specified intervertebral disk degeneration
0.654 0.346 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.654 0.346 0.000
M51.9 Intervertebral disk disorder, unspecified
0.654 0.346 0.000
M51.8 Other specified intervertebral disk disorders
0.654 0.346 0.000
M51.4 Schmorl's nodes
0.654 0.346 0.000
M54.2 Cervicalgia
0.653 0.347 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.653 0.347 0.000
C18.2 Ascending colon
0.652 0.348 0.000
I60-I69 Cerebrovascular diseases
0.652 0.348 0.000
M07.3 Other psoriatic arthropathies
0.652 0.348 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.651 0.349 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.651 0.349 0.000
M47.84 Other spondylosis (Thoracic region)
0.651 0.349 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.651 0.349 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.651 0.349 0.000
Y84.2 Radiological procedure and radiotherapy
0.651 0.349 0.000
I21.9 Acute myocardial infarction, unspecified
0.650 0.350 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.650 0.350 0.000
N20.9 Urinary calculus, unspecified
0.649 0.351 0.000
C18.9 Colon, unspecified
0.649 0.351 0.000
I44.1 Atrioventricular block, second degree
0.648 0.352 0.000
K82 Other diseases of gallbladder
0.647 0.352 0.000
E65-E68 Obesity and other hyperalimentation
0.647 0.353 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.647 0.353 0.000
M85 Other disorders of bone density and structure
0.647 0.353 0.000
M48.9 Spondylopathy, unspecified
0.646 0.354 0.000
M48.8 Other specified spondylopathies
0.646 0.354 0.000
M48.4 Fatigue fracture of vertebra
0.646 0.354 0.000
M48.3 Traumatic spondylopathy
0.646 0.354 0.000
M48.2 Kissing spine
0.646 0.354 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.646 0.354 0.000
I34.0 Mitral (valve) insufficiency
0.645 0.355 0.000
K46 Unspecified abdominal hernia
0.645 0.355 0.000
B35-B49 Mycoses
0.644 0.356 0.000
M10.99 Gout, unspecified (Site unspecified)
0.644 0.356 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.644 0.356 0.000
C15 Malignant neoplasm of oesophagus
0.643 0.357 0.000
I31 Other diseases of pericardium
0.643 0.357 0.000
N03 Chronic nephritic syndrome
0.643 0.357 0.000
I74 Arterial embolism and thrombosis
0.642 0.357 0.000
L29 Pruritus
0.642 0.358 0.000
Y83.5 Amputation of limb(s)
0.641 0.359 0.000
Y83.0 Surgical operation with transplant of whole organ
0.641 0.359 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.641 0.359 0.000
A00-A09 Intestinal infectious diseases
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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