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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111571219
log Bayes Factor = 14.5965
Chromosome 9   position 102,420,794  (GRCh37) Explore rs111571219 on Ensembl!
Variant rs111571219 is part of Cluster X0177

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.996 0.004 0.000
N18 Chronic renal failure
0.992 0.008 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.988 0.012 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
S50-S59 Injuries to the elbow and forearm
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
N19 Unspecified renal failure
0.979 0.021 0.000
C79 Secondary malignant neoplasm of other sites
0.979 0.021 0.000
J40-J47 Chronic lower respiratory diseases
0.975 0.025 0.000
S52 Fracture of forearm
0.974 0.026 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.969 0.031 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.968 0.032 0.000
S52.5 Fracture of lower end of radius
0.967 0.033 0.000
N30-N39 Other diseases of urinary system
0.966 0.034 0.000
J90-J94 Other diseases of pleura
0.966 0.034 0.000
N18.9 Chronic renal failure, unspecified
0.965 0.035 0.000
S52.50 Fracture of lower end of radius (closed)
0.963 0.037 0.000
N10-N16 Renal tubulo-interstitial diseases
0.962 0.038 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.961 0.039 0.000
J47 Bronchiectasis
0.950 0.050 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.949 0.051 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.941 0.059 0.000
J90 Pleural effusion, not elsewhere classified
0.940 0.060 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.940 0.060 0.000
E70-E90 Metabolic disorders
0.940 0.060 0.000
Chapter IX Diseases of the circulatory system
0.936 0.064 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.928 0.072 0.000
J09-J18 Influenza and pneumonia
0.924 0.076 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.924 0.076 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.922 0.078 0.000
N13 Obstructive and reflux uropathy
0.922 0.078 0.000
J43 Emphysema
0.920 0.080 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.918 0.082 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.915 0.085 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.914 0.086 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.912 0.088 0.000
N39 Other disorders of urinary system
0.908 0.092 0.000
N17 Acute renal failure
0.906 0.094 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.905 0.095 0.000
D50-D53 Nutritional anaemias
0.904 0.096 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.899 0.101 0.000
M70-M79 Other soft tissue disorders
0.898 0.102 0.000
E87.2 Acidosis
0.893 0.107 0.000
Y95 Nosocomial condition
0.884 0.116 0.000
J43.9 Emphysema, unspecified
0.881 0.119 0.000
E86 Volume depletion
0.875 0.125 0.000
D50 Iron deficiency anaemia
0.874 0.126 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.872 0.128 0.000
J18 Pneumonia, organism unspecified
0.871 0.129 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.867 0.133 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.865 0.135 0.000
R00 Abnormalities of heart beat
0.862 0.138 0.000
B35-B49 Mycoses
0.862 0.138 0.000
S60-S69 Injuries to the wrist and hand
0.862 0.138 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.859 0.141 0.000
C78.0 Secondary malignant neoplasm of lung
0.859 0.141 0.000
I60-I69 Cerebrovascular diseases
0.857 0.143 0.000
J20-J22 Other acute lower respiratory infections
0.854 0.146 0.000
C78.2 Secondary malignant neoplasm of pleura
0.850 0.150 0.000
C64-C68 Malignant neoplasms of urinary tract
0.848 0.152 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.848 0.152 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.848 0.152 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.847 0.153 0.000
N39.0 Urinary tract infection, site not specified
0.842 0.158 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.841 0.159 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.840 0.160 0.000
J18.9 Pneumonia, unspecified
0.840 0.160 0.000
N17.9 Acute renal failure, unspecified
0.839 0.161 0.000
C15-C26 Malignant neoplasms of digestive organs
0.838 0.162 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.835 0.164 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.833 0.167 0.000
M75 Shoulder lesions
0.832 0.168 0.000
C78.7 Secondary malignant neoplasm of liver
0.832 0.168 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.826 0.174 0.000
N39.3 Stress incontinence
0.826 0.174 0.000
R00.1 Bradycardia, unspecified
0.825 0.175 0.000
N18.3 Chronic kidney disease, stage 3
0.825 0.175 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.822 0.178 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.821 0.179 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.818 0.182 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.817 0.183 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.811 0.189 0.000
N25-N29 Other disorders of kidney and ureter
0.809 0.191 0.000
R06 Abnormalities of breathing
0.809 0.191 0.000
N18.5 Chronic kidney disease, stage 5
0.808 0.192 0.000
N36 Other disorders of urethra
0.808 0.192 0.000
D50.8 Other iron deficiency anaemias
0.807 0.193 0.000
N18.0 End-stage renal disease
0.805 0.195 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.803 0.197 0.000
N60-N64 Disorders of breast
0.801 0.199 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.800 0.200 0.000
Chapter V Mental and behavioural disorders
0.797 0.203 0.000
N10 Acute tubulo-interstitial nephritis
0.795 0.205 0.000
E87.6 Hypokalaemia
0.794 0.206 0.000
Chapter XXII Codes for special purposes
0.794 0.206 0.000
Chapter XXI Factors influencing health status and contact with health services
0.794 0.206 0.000
N20-N23 Urolithiasis
0.793 0.207 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.787 0.213 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.787 0.213 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.786 0.214 0.000
S20-S29 Injuries to the thorax
0.785 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
M75.4 Impingement syndrome of shoulder
0.783 0.217 0.000
R03.1 Nonspecific low blood-pressure reading
0.783 0.217 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.779 0.221 0.000
N18.4 Chronic kidney disease, stage 4
0.772 0.227 0.000
Chapter VI Diseases of the nervous system
0.772 0.228 0.000
S40-S49 Injuries to the shoulder and upper arm
0.771 0.229 0.000
D50.9 Iron deficiency anaemia, unspecified
0.771 0.229 0.000
C60-C63 Malignant neoplasms of male genital organs
0.769 0.231 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.769 0.231 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.769 0.231 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.769 0.231 0.000
M79.0 Rheumatism, unspecified
0.766 0.234 0.000
E83 Disorders of mineral metabolism
0.766 0.234 0.000
N00-N08 Glomerular diseases
0.762 0.238 0.000
A00-A09 Intestinal infectious diseases
0.757 0.243 0.000
I20-I25 Ischaemic heart diseases
0.757 0.243 0.000
M80-M85 Disorders of bone density and structure
0.756 0.244 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.756 0.244 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.753 0.247 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.752 0.248 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.752 0.248 0.000
C77.3 Axillary and upper limb lymph nodes
0.752 0.248 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.752 0.248 0.000
J22 Unspecified acute lower respiratory infection
0.751 0.249 0.000
T86 Failure and rejection of transplanted organs and tissues
0.751 0.249 0.000
W20-W49 Exposure to inanimate mechanical forces
0.749 0.251 0.000
Y40 Systemic antibiotics
0.748 0.252 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.747 0.253 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.745 0.255 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.255 0.000
J91 Pleural effusion in conditions classified elsewhere
0.744 0.256 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.744 0.256 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.743 0.257 0.000
R00.2 Palpitations
0.743 0.257 0.000
I69 Sequelae of cerebrovascular disease
0.740 0.260 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.739 0.261 0.000
R73 Elevated blood glucose level
0.739 0.261 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.738 0.262 0.000
I80 Phlebitis and thrombophlebitis
0.737 0.263 0.000
C67 Malignant neoplasm of bladder
0.737 0.263 0.000
Chapter VIII Diseases of the ear and mastoid process
0.735 0.265 0.000
C79.2 Secondary malignant neoplasm of skin
0.733 0.266 0.000
R06.5 Mouth breathing
0.733 0.267 0.000
D00-D09 In situ neoplasms
0.733 0.267 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.733 0.267 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.732 0.268 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.732 0.268 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.730 0.270 0.000
B37 Candidiasis
0.730 0.270 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.730 0.270 0.000
J60-J70 Lung diseases due to external agents
0.730 0.270 0.000
Y44 Agents primarily affecting blood constituents
0.730 0.270 0.000
V10-V19 Pedal cyclist injured in transport accident
0.728 0.272 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.727 0.273 0.000
M77 Other enthesopathies
0.725 0.275 0.000
C80 Malignant neoplasm without specification of site
0.724 0.275 0.000
C50-C50 Malignant neoplasm of breast
0.724 0.276 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.723 0.277 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.723 0.277 0.000
S52.6 Fracture of lower end of both ulna and radius
0.722 0.278 0.000
J95-J99 Other diseases of the respiratory system
0.722 0.278 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.720 0.280 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.718 0.282 0.000
M45-M49 Spondylopathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
B25-B34 Other viral diseases
0.715 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.714 0.286 0.000
C51-C58 Malignant neoplasms of female genital organs
0.713 0.287 0.000
I10-I15 Hypertensive diseases
0.713 0.287 0.000
T66-T78 Other and unspecified effects of external causes
0.712 0.288 0.000
N18.8 Other chronic renal failure
0.711 0.289 0.000
N18.2 Chronic kidney disease, stage 2
0.711 0.289 0.000
N18.1 Chronic kidney disease, stage 1
0.711 0.289 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.710 0.290 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.709 0.291 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.709 0.291 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.709 0.291 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.709 0.291 0.000
I62 Other nontraumatic intracranial haemorrhage
0.708 0.292 0.000
D80-D89 Certain disorders involving the immune mechanism
0.708 0.292 0.000
N39.8 Other specified disorders of urinary system
0.707 0.292 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.706 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.706 0.293 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.706 0.294 0.000
S59 Other and unspecified injuries of forearm
0.706 0.294 0.000
S58 Traumatic amputation of forearm
0.706 0.294 0.000
S57 Crushing injury of forearm
0.706 0.294 0.000
S56 Injury of muscle and tendon at forearm level
0.706 0.294 0.000
S55 Injury of blood vessels at forearm level
0.706 0.294 0.000
S54 Injury of nerves at forearm level
0.706 0.294 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.706 0.294 0.000
S51 Open wound of forearm
0.706 0.294 0.000
S50 Superficial injury of forearm
0.706 0.294 0.000
N36.0 Urethral fistula
0.704 0.296 0.000
S80-S89 Injuries to the knee and lower leg
0.704 0.296 0.000
M50-M54 Other dorsopathies
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.702 0.298 0.000
C79.6 Secondary malignant neoplasm of ovary
0.702 0.298 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.702 0.298 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.702 0.298 0.000
N13.4 Hydroureter
0.700 0.299 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.700 0.299 0.000
J41 Simple and mucopurulent chronic bronchitis
0.699 0.301 0.000
J46 Status asthmaticus
0.699 0.301 0.000
J42 Unspecified chronic bronchitis
0.699 0.301 0.000
S52.9 Fracture of forearm, part unspecified
0.698 0.302 0.000
S52.8 Fracture of other parts of forearm
0.698 0.302 0.000
S52.7 Multiple fractures of forearm
0.698 0.302 0.000
S52.4 Fracture of shafts of both ulna and radius
0.698 0.302 0.000
S52.3 Fracture of shaft of radius
0.698 0.302 0.000
S52.2 Fracture of shaft of ulna
0.698 0.302 0.000
S52.1 Fracture of upper end of radius
0.698 0.302 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.698 0.302 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.697 0.303 0.000
M75.1 Rotator cuff syndrome
0.697 0.303 0.000
M86-M90 Other osteopathies
0.695 0.305 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.695 0.305 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.694 0.306 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.694 0.306 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.694 0.306 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.694 0.306 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.694 0.306 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.694 0.306 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.694 0.306 0.000
B07 Viral warts
0.694 0.306 0.000
S52.51 Fracture of lower end of radius (open)
0.693 0.306 0.000
N37 Urethral disorders in diseases classified elsewhere
0.693 0.307 0.000
N34 Urethritis and urethral syndrome
0.693 0.307 0.000
N33 Bladder disorders in diseases classified elsewhere
0.693 0.307 0.000
J94 Other pleural conditions
0.692 0.307 0.000
C18 Malignant neoplasm of colon
0.692 0.308 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.692 0.308 0.000
E88 Other metabolic disorders
0.692 0.308 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.690 0.310 0.000
N15 Other renal tubulo-interstitial diseases
0.690 0.310 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.690 0.310 0.000
N11 Chronic tubulo-interstitial nephritis
0.690 0.310 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.689 0.311 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.689 0.311 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.689 0.311 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.689 0.311 0.000
C34 Malignant neoplasm of bronchus and lung
0.689 0.311 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.687 0.313 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.686 0.313 0.000
R79 Other abnormal findings of blood chemistry
0.685 0.315 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.685 0.315 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.684 0.316 0.000
E50-E64 Other nutritional deficiencies
0.682 0.318 0.000
M79.7 Fibromyalgia
0.682 0.318 0.000
E40-E46 Malnutrition
0.681 0.319 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.680 0.320 0.000
B35 Dermatophytosis
0.680 0.320 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.680 0.320 0.000
W00-W19 Falls
0.679 0.321 0.000
J93 Pneumothorax
0.678 0.322 0.000
N13.8 Other obstructive and reflux uropathy
0.677 0.323 0.000
C77.9 Lymph node, unspecified
0.677 0.323 0.000
N60 Benign mammary dysplasia
0.676 0.324 0.000
C15 Malignant neoplasm of oesophagus
0.676 0.324 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.675 0.325 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.675 0.325 0.000
J92 Pleural plaque
0.675 0.325 0.000
D55-D59 Haemolytic anaemias
0.674 0.325 0.000
R30-R39 Symptoms and signs involving the urinary system
0.674 0.326 0.000
Z50 Care involving use of rehabilitation procedures
0.674 0.326 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.674 0.326 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.674 0.326 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.674 0.326 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.674 0.326 0.000
E85 Amyloidosis
0.674 0.326 0.000
E84 Cystic fibrosis
0.674 0.326 0.000
E79 Disorders of purine and pyrimidine metabolism
0.674 0.326 0.000
E77 Disorders of glycoprotein metabolism
0.674 0.326 0.000
E76 Disorders of glycosaminoglycan metabolism
0.674 0.326 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.674 0.326 0.000
E74 Other disorders of carbohydrate metabolism
0.674 0.326 0.000
E73 Lactose intolerance
0.674 0.326 0.000
E72 Other disorders of amino-acid metabolism
0.674 0.326 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.674 0.326 0.000
E70 Disorders of aromatic amino-acid metabolism
0.674 0.326 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.674 0.326 0.000
N63 Unspecified lump in breast
0.673 0.327 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.672 0.328 0.000
D52 Folate deficiency anaemia
0.672 0.328 0.000
S64 Injury of nerves at wrist and hand level
0.672 0.328 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.672 0.328 0.000
I00-I02 Acute rheumatic fever
0.671 0.329 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.671 0.329 0.000
I05-I09 Chronic rheumatic heart diseases
0.670 0.330 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.670 0.330 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.669 0.331 0.000
N32 Other disorders of bladder
0.669 0.331 0.000
N76 Other inflammation of vagina and vulva
0.668 0.332 0.000
R02 Gangrene, not elsewhere classified
0.668 0.332 0.000
M79.6 Pain in limb
0.668 0.332 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.666 0.334 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.666 0.334 0.000
R25 Abnormal involuntary movements
0.664 0.336 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.663 0.337 0.000
J17 Pneumonia in diseases classified elsewhere
0.662 0.337 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.662 0.337 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.662 0.337 0.000
J12 Viral pneumonia, not elsewhere classified
0.662 0.337 0.000
J11 Influenza, virus not identified
0.662 0.337 0.000
J10 Influenza due to identified influenza virus
0.662 0.337 0.000
J14 Pneumonia due to Haemophilus influenzae
0.662 0.337 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.662 0.337 0.000
J09 Influenza due to certain identified influenza virus
0.662 0.337 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.662 0.337 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.662 0.337 0.000
Y98 Lifestyle-related condition
0.662 0.337 0.000
Y97 Environmental-pollution-related condition
0.662 0.337 0.000
Y96 Work-related condition
0.662 0.337 0.000
D51 Vitamin B12 deficiency anaemia
0.662 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.661 0.339 0.000
Y58 Bacterial vaccines
0.661 0.339 0.000
Y57 Other and unspecified drugs and medicaments
0.661 0.339 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.339 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.661 0.339 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.339 0.000
Y52 Agents primarily affecting the cardiovascular system
0.661 0.339 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.661 0.339 0.000
Y48 Anaesthetics and therapeutic gases
0.661 0.339 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.661 0.339 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.661 0.339 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.661 0.339 0.000
N13.6 Pyonephrosis
0.661 0.339 0.000
J43.8 Other emphysema
0.660 0.340 0.000
J43.2 Centrilobular emphysema
0.660 0.340 0.000
J43.1 Panlobular emphysema
0.660 0.340 0.000
J43.0 MacLeod's syndrome
0.660 0.340 0.000
A30-A49 Other bacterial diseases
0.659 0.341 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.658 0.341 0.000
E87.4 Mixed disorder of acid-base balance
0.658 0.341 0.000
E87.3 Alkalosis
0.658 0.341 0.000
E87.0 Hyperosmolality and hypernatraemia
0.658 0.341 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.658 0.342 0.000
I22 Subsequent myocardial infarction
0.658 0.342 0.000
I20 Angina pectoris
0.658 0.342 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.657 0.343 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.656 0.344 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.655 0.345 0.000
N23 Unspecified renal colic
0.655 0.345 0.000
Z46 Fitting and adjustment of other devices
0.654 0.346 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.654 0.346 0.000
M91-M94 Chondropathies
0.654 0.346 0.000
M60-M63 Disorders of muscles
0.654 0.346 0.000
M00-M03 Infectious arthropathies
0.654 0.346 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.654 0.346 0.000
N75 Diseases of Bartholin's gland
0.654 0.346 0.000
R74 Abnormal serum enzyme levels
0.653 0.346 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.653 0.347 0.000
T18 Foreign body in alimentary tract
0.653 0.347 0.000
R73.9 Hyperglycaemia, unspecified
0.652 0.348 0.000
N39.2 Orthostatic proteinuria, unspecified
0.651 0.349 0.000
N39.1 Persistent proteinuria, unspecified
0.651 0.349 0.000
S62 Fracture at wrist and hand level
0.651 0.349 0.000
S68 Traumatic amputation of wrist and hand
0.650 0.350 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.650 0.350 0.000
N17.8 Other acute renal failure
0.650 0.350 0.000
N17.2 Acute renal failure with medullary necrosis
0.650 0.350 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.650 0.350 0.000
N17.0 Acute renal failure with tubular necrosis
0.650 0.350 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.649 0.351 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.649 0.351 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.649 0.351 0.000
T82.3 Mechanical complication of other vascular grafts
0.649 0.351 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.649 0.351 0.000
T82.1 Mechanical complication of cardiac electronic device
0.649 0.351 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.649 0.351 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.649 0.351 0.000
D53 Other nutritional anaemias
0.648 0.352 0.000
N13.3 Other and unspecified hydronephrosis
0.647 0.353 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.647 0.353 0.000
J44 Other chronic obstructive pulmonary disease
0.647 0.353 0.000
D60-D64 Aplastic and other anaemias
0.646 0.354 0.000
N99-N99 Other disorders of the genitourinary system
0.646 0.354 0.000
T17 Foreign body in respiratory tract
0.645 0.354 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.645 0.354 0.000
H80-H83 Diseases of inner ear
0.645 0.355 0.000
Y45.0 Opioids and related analgesics
0.644 0.356 0.000
M76 Enthesopathies of lower limb, excluding foot
0.644 0.356 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.644 0.356 0.000
M71 Other bursopathies
0.644 0.356 0.000
S60 Superficial injury of wrist and hand
0.644 0.356 0.000
E20-E35 Disorders of other endocrine glands
0.644 0.356 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.643 0.357 0.000
C67.9 Bladder, unspecified
0.642 0.358 0.000
N30 Cystitis
0.642 0.358 0.000
E87.7 Fluid overload
0.642 0.358 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.642 0.358 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.642 0.358 0.000
S52.0 Fracture of upper end of ulna
0.642 0.358 0.000
M79.8 Other specified soft tissue disorders
0.641 0.359 0.000
E65-E68 Obesity and other hyperalimentation
0.639 0.361 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.637 0.363 0.000
J40 Bronchitis, not specified as acute or chronic
0.637 0.363 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.636 0.364 0.000
J18.0 Bronchopneumonia, unspecified
0.635 0.365 0.000
E83.4 Disorders of magnesium metabolism
0.633 0.367 0.000
L03 Cellulitis
0.633 0.367 0.000
R06.8 Other and unspecified abnormalities of breathing
0.633 0.367 0.000
B02 Zoster [herpes zoster]
0.632 0.368 0.000
N73 Other female pelvic inflammatory diseases
0.632 0.368 0.000
I63 Cerebral infarction
0.632 0.368 0.000
R06.2 Wheezing
0.631 0.369 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.631 0.369 0.000
S72 Fracture of femur
0.631 0.369 0.000
N70 Salpingitis and oophoritis
0.631 0.369 0.000
Y49.2 Other and unspecified antidepressants
0.630 0.370 0.000
G30-G32 Other degenerative diseases of the nervous system
0.627 0.373 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.627 0.373 0.000
D50.1 Sideropenic dysphagia
0.626 0.374 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.625 0.375 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.625 0.375 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.625 0.375 0.000
J18.8 Other pneumonia, organism unspecified
0.624 0.375 0.000
J18.2 Hypostatic pneumonia, unspecified
0.624 0.375 0.000
C18.9 Colon, unspecified
0.624 0.376 0.000
F80-F89 Disorders of psychological development
0.623 0.377 0.000
R01 Cardiac murmurs and other cardiac sounds
0.621 0.379 0.000
I61 Intracerebral haemorrhage
0.619 0.381 0.000
C16 Malignant neoplasm of stomach
0.619 0.381 0.000
C25 Malignant neoplasm of pancreas
0.618 0.382 0.000
B48 Other mycoses, not elsewhere classified
0.618 0.382 0.000
B47 Mycetoma
0.618 0.382 0.000
B46 Zygomycosis
0.618 0.382 0.000
B45 Cryptococcosis
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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