TreeWAS – Variant ID: rs111646341

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.0 Calculus of kidney	0.000	0.991	0.009
L82 Seborrhoeic keratosis	0.000	0.994	0.006
M47.86 Other spondylosis (Lumbar region)	0.000	0.994	0.006
M75.1 Rotator cuff syndrome	0.000	0.995	0.005
M75 Shoulder lesions	0.000	0.995	0.005
M75.0 Adhesive capsulitis of shoulder	0.000	0.995	0.005
M75.5 Bursitis of shoulder	0.000	0.996	0.004
N13.8 Other obstructive and reflux uropathy	0.004	0.996	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.996	0.004
M75.4 Impingement syndrome of shoulder	0.000	0.996	0.004
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
M75.2 Bicipital tendinitis	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
M75.8 Other shoulder lesions	0.000	0.996	0.004
M75.9 Shoulder lesion, unspecified	0.000	0.996	0.004
N20 Calculus of kidney and ureter	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.004	0.996	0.000
N13 Obstructive and reflux uropathy	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.997	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.997	0.003
N13.3 Other and unspecified hydronephrosis	0.003	0.997	0.000
N20.9 Urinary calculus, unspecified	0.000	0.997	0.003
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.003	0.997	0.000
L40.9 Psoriasis, unspecified	0.003	0.997	0.000
B07 Viral warts	0.000	0.997	0.003
R47.0 Dysphasia and aphasia	0.003	0.997	0.000
Z97.4 Presence of external hearing-aid	0.000	0.997	0.003
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.003	0.997	0.000
M47.8 Other spondylosis	0.000	0.997	0.003
M75.81 Other shoulder lesions, right shoulder	0.000	0.997	0.003
N13.4 Hydroureter	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.997	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.003	0.997	0.000
N13.6 Pyonephrosis	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
S82.10 Fracture of upper end of tibia (closed)	0.003	0.997	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.997	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.997	0.000
D51.2 Transcobalamin II deficiency	0.002	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.997	0.000
N32.8 Other specified disorders of bladder	0.000	0.997	0.003
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.003	0.997	0.000
S82.0 Fracture of patella	0.002	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.002
O72.1 Other immediate postpartum haemorrhage	0.000	0.997	0.003
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.998	0.002
M47.84 Other spondylosis (Thoracic region)	0.000	0.998	0.002
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.998	0.002
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
Z97 Presence of other devices	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
N80.1 Endometriosis of ovary	0.000	0.998	0.002
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
R20.2 Paraesthesia of skin	0.002	0.998	0.000
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
L57.0 Actinic keratosis	0.000	0.998	0.002
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
R87.6 Abnormal cytological findings	0.000	0.998	0.002
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.998	0.002
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.998	0.002
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.998	0.002
Z97.0 Presence of artificial eye	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
E04 Other non-toxic goitre	0.002	0.998	0.000
R20 Disturbances of skin sensation	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
R18 Ascites	0.000	0.998	0.002
R49.8 Other and unspecified voice disturbances	0.002	0.998	0.000
D27 Benign neoplasm of ovary	0.002	0.998	0.000
L90 Atrophic disorders of skin	0.000	0.998	0.002
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
C67.5 Bladder neck	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
J03 Acute tonsillitis	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
M47 Spondylosis	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
R49 Voice disturbances	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
C67.1 Dome of bladder	0.002	0.998	0.000
G56.2 Lesion of ulnar nerve	0.002	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.001	0.998	0.000
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.002	0.998	0.000
R20.1 Hypoaesthesia of skin	0.002	0.998	0.000
R20.0 Anaesthesia of skin	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.001	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
C67.7 Urachus	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
N80.9 Endometriosis, unspecified	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
L90.9 Atrophic disorder of skin, unspecified	0.000	0.998	0.001
L90.8 Other atrophic disorders of skin	0.000	0.998	0.001
L90.6 Striae atrophicae	0.000	0.998	0.001
L90.4 Acrodermatitis chronica atrophicans	0.000	0.998	0.001
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.998	0.001
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.998	0.001
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.998	0.001
M47.9 Spondylosis, unspecified	0.000	0.998	0.002
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
S42.31 Fracture of shaft of humerus (open)	0.001	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.998	0.000
Q27.4 Congenital phlebectasia	0.001	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.001	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.001	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.001	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.001	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
J03.8 Acute tonsillitis due to other specified organisms	0.001	0.998	0.000
J03.0 Streptococcal tonsillitis	0.001	0.998	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.998	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.001	0.998	0.000
Q80.8 Other congenital ichthyosis	0.001	0.998	0.000
Q80.4 Harlequin foetus	0.001	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.001	0.998	0.000
Q80.2 Lamellar ichthyosis	0.001	0.998	0.000
Q80.1 X-linked ichthyosis	0.001	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.001	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.001	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.001	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.001	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.001	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.001	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.2 Mastocytosis	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.001	0.998	0.000
Q83.8 Other congenital malformations of breast	0.001	0.998	0.000
Q83.3 Accessory nipple	0.001	0.998	0.000
Q83.2 Absent nipple	0.001	0.998	0.000
Q83.1 Accessory breast	0.001	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.001	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.001	0.998	0.000
Q84.6 Other congenital malformations of nails	0.001	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.001	0.998	0.000
Q84.4 Congenital leukonychia	0.001	0.998	0.000
Q84.3 Anonychia	0.001	0.998	0.000
Q84.2 Other congenital malformations of hair	0.001	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.001	0.998	0.000
Q84.0 Congenital alopecia	0.001	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.998	0.000
Q85.1 Tuberous sclerosis	0.001	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.001	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.001	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.001	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
L85 Other epidermal thickening	0.000	0.998	0.002
L83 Acanthosis nigricans	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.001	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.998	0.000
Q15 Other congenital malformations of eye	0.001	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.998	0.000
Q12 Congenital lens malformations	0.001	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.001	0.998	0.000
S80-S89 Injuries to the knee and lower leg	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.001	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.998	0.000
H02.3 Blepharochalasis	0.002	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.998	0.000
Q20.4 Double inlet ventricle	0.001	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.998	0.000
Q20.2 Double outlet left ventricle	0.001	0.998	0.000
Q20.1 Double outlet right ventricle	0.001	0.998	0.000
Q20.0 Common arterial trunk	0.001	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.998	0.000
Q22.5 Ebstein's anomaly	0.001	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.001	0.998	0.000
Q22.0 Pulmonary valve atresia	0.001	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.001	0.998	0.000
Q24.6 Congenital heart block	0.001	0.998	0.000
Q24.5 Malformation of coronary vessels	0.001	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.998	0.000
Q24.2 Cor triatriatum	0.001	0.998	0.000
Q24.1 Levocardia	0.001	0.998	0.000
Q24.0 Dextrocardia	0.001	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.998	0.000
Q25.3 Stenosis of aorta	0.001	0.998	0.000
Q25.2 Atresia of aorta	0.001	0.998	0.000
Q25.1 Coarctation of aorta	0.001	0.998	0.000
Q25.0 Patent ductus arteriosus	0.001	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.1 Persistent left superior vena cava	0.001	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.001	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.001	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.001	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.001	0.998	0.000
Q39.4 Oesophageal web	0.001	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.001	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.001	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.001	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.001	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.001	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.001	0.998	0.000
Q40.1 Congenital hiatus hernia	0.001	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.001	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.998	0.000
Q45.1 Annular pancreas	0.001	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.998	0.000
R49.2 Hypernasality and hyponasality	0.001	0.998	0.000
R49.1 Aphonia	0.001	0.998	0.000
H02 Other disorders of eyelid	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.001
L85.8 Other specified epidermal thickening	0.000	0.998	0.001
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.998	0.001
S82.4 Fracture of fibula alone	0.001	0.998	0.000
Q65 Congenital deformities of hip	0.001	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.001	0.998	0.000
K82.8 Other specified diseases of gallbladder	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.998	0.000
Q18.7 Microcheilia	0.001	0.998	0.000
Q18.6 Macrocheilia	0.001	0.998	0.000
Q18.5 Microstomia	0.001	0.998	0.000
Q18.4 Macrostomia	0.001	0.998	0.000
Q18.3 Webbing of neck	0.001	0.998	0.000
Q18.2 Other branchial cleft malformations	0.001	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.001	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.998	0.000
Q38.2 Macroglossia	0.001	0.998	0.000
Q38.1 Ankyloglossia	0.001	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.001	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.001	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.001	0.998	0.000
H02.6 Xanthelasma of eyelid	0.001	0.998	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.998	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.000
Q64 Other congenital malformations of urinary system	0.001	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.998	0.000
R32 Unspecified urinary incontinence	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.998	0.001
L94 Other localised connective tissue disorders	0.000	0.998	0.001
L87 Transepidermal elimination disorders	0.000	0.998	0.001
L88 Pyoderma gangrenosum	0.000	0.998	0.001
L86 Keratoderma in diseases classified elsewhere	0.000	0.998	0.001
L80 Vitiligo	0.000	0.998	0.001
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.998	0.000
Q73 Reduction defects of unspecified limb	0.001	0.998	0.000
Q72 Reduction defects of lower limb	0.001	0.998	0.000
Q71 Reduction defects of upper limb	0.001	0.998	0.000
Q70 Syndactyly	0.001	0.998	0.000
Q69 Polydactyly	0.001	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T36 Poisoning by systemic antibiotics	0.001	0.998	0.000
L89.1 Stage II decubitus ulcer	0.000	0.998	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.998	0.000
L81 Other disorders of pigmentation	0.000	0.998	0.001
Q34 Other congenital malformations of respiratory system	0.001	0.998	0.000
Q33 Congenital malformations of lung	0.001	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.998	0.000
Q31 Congenital malformations of larynx	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
Q37 Cleft palate with cleft lip	0.001	0.998	0.000
Q36 Cleft lip	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations