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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111763904
log Bayes Factor = 13.1327
Chromosome 6   position 43,091,942  (GRCh37) Explore rs111763904 on Ensembl!
Variant rs111763904 is part of Cluster X0074

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.996 0.004 0.000
S00-S09 Injuries to the head
0.991 0.009 0.000
M54 Dorsalgia
0.986 0.014 0.000
N39 Other disorders of urinary system
0.985 0.015 0.000
N30-N39 Other diseases of urinary system
0.985 0.015 0.000
M45-M49 Spondylopathies
0.984 0.016 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
N39.0 Urinary tract infection, site not specified
0.982 0.018 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.978 0.022 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.976 0.024 0.000
H25-H28 Disorders of lens
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.967 0.033 0.000
H26 Other cataract
0.967 0.033 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.966 0.034 0.000
H65-H75 Diseases of middle ear and mastoid
0.959 0.041 0.000
Chapter XXI Factors influencing health status and contact with health services
0.959 0.041 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.957 0.043 0.000
Z41 Procedures for purposes other than remedying health state
0.953 0.047 0.000
H26.9 Cataract, unspecified
0.953 0.047 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.952 0.048 0.000
M50 Cervical disk disorders
0.952 0.048 0.000
Z50 Care involving use of rehabilitation procedures
0.952 0.048 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.951 0.049 0.000
H90-H95 Other disorders of ear
0.940 0.060 0.000
S01 Open wound of head
0.935 0.065 0.000
E00-E07 Disorders of thyroid gland
0.935 0.065 0.000
S02 Fracture of skull and facial bones
0.935 0.065 0.000
M80-M85 Disorders of bone density and structure
0.928 0.072 0.000
M47 Spondylosis
0.922 0.078 0.000
M54.5 Low back pain
0.920 0.080 0.000
H26.4 After-cataract
0.918 0.082 0.000
S06 Intracranial injury
0.918 0.082 0.000
M48 Other spondylopathies
0.917 0.083 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.914 0.086 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.912 0.088 0.000
H20 Iridocyclitis
0.905 0.095 0.000
Z50.1 Other physical therapy
0.904 0.096 0.000
S70-S79 Injuries to the hip and thigh
0.903 0.097 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
D73 Diseases of spleen
0.899 0.101 0.000
M54.4 Lumbago with sciatica
0.898 0.102 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.893 0.107 0.000
E20-E35 Disorders of other endocrine glands
0.892 0.108 0.000
M50.2 Other cervical disk displacement
0.891 0.109 0.000
M65-M68 Disorders of synovium and tendon
0.890 0.110 0.000
T79-T79 Certain early complications of trauma
0.889 0.111 0.000
N39.3 Stress incontinence
0.889 0.111 0.000
Z50.8 Care involving use of rehabilitation procedures
0.885 0.115 0.000
D70 Agranulocytosis
0.881 0.119 0.000
O00-O08 Pregnancy with abortive outcome
0.878 0.122 0.000
M47.9 Spondylosis, unspecified
0.878 0.122 0.000
S20-S29 Injuries to the thorax
0.878 0.122 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.878 0.122 0.000
N39.9 Disorder of urinary system, unspecified
0.877 0.123 0.000
M20-M25 Other joint disorders
0.874 0.126 0.000
N30 Cystitis
0.868 0.132 0.000
H91 Other hearing loss
0.867 0.133 0.000
H60-H62 Diseases of external ear
0.867 0.133 0.000
N00-N08 Glomerular diseases
0.867 0.133 0.000
S40-S49 Injuries to the shoulder and upper arm
0.860 0.140 0.000
M84 Disorders of continuity of bone
0.859 0.141 0.000
S02.2 Fracture of nasal bones
0.858 0.142 0.000
H53-H54 Visual disturbances and blindness
0.858 0.142 0.000
M54.1 Radiculopathy
0.858 0.142 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.849 0.151 0.000
E50-E64 Other nutritional deficiencies
0.840 0.160 0.000
D73.0 Hyposplenism
0.839 0.161 0.000
H18 Other disorders of cornea
0.838 0.162 0.000
Chapter VI Diseases of the nervous system
0.837 0.163 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.835 0.165 0.000
S50-S59 Injuries to the elbow and forearm
0.833 0.167 0.000
H73 Other disorders of tympanic membrane
0.830 0.169 0.000
M54.57 Low back pain (Lumbosacral region)
0.830 0.170 0.000
S01.2 Open wound of nose
0.828 0.172 0.000
E05.9 Thyrotoxicosis, unspecified
0.826 0.174 0.000
M51 Other intervertebral disk disorders
0.826 0.174 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.824 0.176 0.000
H20.9 Iridocyclitis, unspecified
0.824 0.176 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.819 0.181 0.000
M48.0 Spinal stenosis
0.816 0.184 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.816 0.184 0.000
H91.9 Hearing loss, unspecified
0.815 0.185 0.000
H74 Other disorders of middle ear and mastoid
0.811 0.189 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.810 0.190 0.000
H54 Blindness and low vision
0.808 0.192 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.807 0.193 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.807 0.193 0.000
M54.59 Low back pain (Site unspecified)
0.807 0.193 0.000
O02 Other abnormal products of conception
0.805 0.195 0.000
M54.3 Sciatica
0.805 0.195 0.000
S02.20 Fracture of nasal bones (closed)
0.803 0.197 0.000
W50-W64 Exposure to animate mechanical forces
0.803 0.197 0.000
E23 Hypofunction and other disorders of pituitary gland
0.802 0.198 0.000
M23 Internal derangement of knee
0.798 0.202 0.000
H43-H45 Disorders of vitreous body and globe
0.798 0.202 0.000
H61 Other disorders of external ear
0.798 0.202 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.796 0.204 0.000
S06.5 Traumatic subdural haemorrhage
0.795 0.205 0.000
H21 Other disorders of iris and ciliary body
0.795 0.205 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.793 0.206 0.000
H90 Conductive and sensorineural hearing loss
0.793 0.207 0.000
S72 Fracture of femur
0.791 0.209 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.791 0.209 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.787 0.213 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.785 0.215 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.785 0.215 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.784 0.216 0.000
H65 Nonsuppurative otitis media
0.784 0.216 0.000
M91-M94 Chondropathies
0.782 0.218 0.000
M50.3 Other cervical disk degeneration
0.781 0.219 0.000
E04 Other non-toxic goitre
0.780 0.220 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.780 0.220 0.000
H17 Corneal scars and opacities
0.779 0.221 0.000
Z50.5 Speech therapy
0.779 0.221 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.778 0.222 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.777 0.223 0.000
S60-S69 Injuries to the wrist and hand
0.776 0.224 0.000
M47.2 Other spondylosis with radiculopathy
0.772 0.227 0.000
H71 Cholesteatoma of middle ear
0.770 0.229 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.769 0.231 0.000
N30.1 Interstitial cystitis (chronic)
0.768 0.232 0.000
N02 Recurrent and persistent haematuria
0.767 0.232 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.767 0.233 0.000
S01.8 Open wound of other parts of head
0.766 0.233 0.000
M54.16 Radiculopathy (Lumbar region)
0.765 0.235 0.000
H69 Other disorders of Eustachian tube
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.764 0.236 0.000
M45 Ankylosing spondylitis
0.764 0.236 0.000
S05 Injury of eye and orbit
0.763 0.237 0.000
D75 Other diseases of blood and blood-forming organs
0.761 0.239 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.761 0.239 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.760 0.240 0.000
E10-E14 Diabetes mellitus
0.759 0.241 0.000
E61 Deficiency of other nutrient elements
0.759 0.241 0.000
S01.7 Multiple open wounds of head
0.758 0.242 0.000
E06 Thyroiditis
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
Z43 Attention to artificial openings
0.757 0.243 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.756 0.244 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.755 0.245 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.755 0.245 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.754 0.246 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.753 0.247 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.753 0.247 0.000
M86-M90 Other osteopathies
0.752 0.248 0.000
M65 Synovitis and tenosynovitis
0.750 0.250 0.000
M84.0 Malunion of fracture
0.750 0.250 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.749 0.251 0.000
S06.2 Diffuse brain injury
0.749 0.251 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.748 0.252 0.000
H55-H59 Other disorders of eye and adnexa
0.748 0.252 0.000
M67 Other disorders of synovium and tendon
0.748 0.252 0.000
H80-H83 Diseases of inner ear
0.747 0.253 0.000
M81 Osteoporosis without pathological fracture
0.746 0.254 0.000
Chapter I Certain infectious and parasitic diseases
0.745 0.255 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
O02.1 Missed abortion
0.742 0.258 0.000
H16 Keratitis
0.741 0.259 0.000
H20.0 Acute and subacute iridocyclitis
0.741 0.259 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.741 0.259 0.000
H73.8 Other specified disorders of tympanic membrane
0.738 0.262 0.000
S70 Superficial injury of hip and thigh
0.738 0.262 0.000
E27 Other disorders of adrenal gland
0.738 0.262 0.000
S01.5 Open wound of lip and oral cavity
0.737 0.262 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.737 0.263 0.000
Y52 Agents primarily affecting the cardiovascular system
0.737 0.263 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
D73.5 Infarction of spleen
0.735 0.265 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.735 0.265 0.000
M40-M43 Deforming dorsopathies
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.733 0.267 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.732 0.268 0.000
V10-V19 Pedal cyclist injured in transport accident
0.731 0.269 0.000
X50-X57 Overexertion, travel and privation
0.730 0.270 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.730 0.270 0.000
Z42 Follow-up care involving plastic surgery
0.730 0.270 0.000
M23.8 Other internal derangements of knee
0.727 0.273 0.000
E23.0 Hypopituitarism
0.725 0.275 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.725 0.275 0.000
N39.8 Other specified disorders of urinary system
0.724 0.275 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.724 0.276 0.000
H30-H36 Disorders of choroid and retina
0.723 0.277 0.000
N05 Unspecified nephritic syndrome
0.722 0.278 0.000
H04 Disorders of lachrymal system
0.722 0.278 0.000
S06.3 Focal brain injury
0.721 0.278 0.000
X60-X84 Intentional self-harm
0.721 0.279 0.000
M70-M79 Other soft tissue disorders
0.720 0.280 0.000
E28 Ovarian dysfunction
0.720 0.280 0.000
Y42.5 Other oestrogens and progestogens
0.720 0.280 0.000
S27 Injury of other and unspecified intrathoracic organs
0.719 0.281 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.719 0.281 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
N99-N99 Other disorders of the genitourinary system
0.716 0.284 0.000
O03 Spontaneous abortion
0.715 0.285 0.000
S02.5 Fracture of tooth
0.715 0.285 0.000
N30.9 Cystitis, unspecified
0.714 0.286 0.000
Z40 Prophylactic surgery
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
H54.4 Blindness, one eye
0.714 0.286 0.000
O04 Medical abortion
0.712 0.288 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.711 0.289 0.000
Y44 Agents primarily affecting blood constituents
0.711 0.289 0.000
S08 Traumatic amputation of part of head
0.710 0.290 0.000
S07 Crushing injury of head
0.710 0.290 0.000
S04 Injury of cranial nerves
0.710 0.290 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.710 0.290 0.000
M46 Other inflammatory spondylopathies
0.709 0.291 0.000
M50.0 Cervical disk disorder with myelopathy
0.708 0.292 0.000
S02.6 Fracture of mandible
0.708 0.292 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.707 0.293 0.000
M54.8 Other dorsalgia
0.707 0.293 0.000
M54.6 Pain in thoracic spine
0.707 0.293 0.000
M54.0 Panniculitis affecting regions of neck and back
0.707 0.293 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.707 0.293 0.000
S02.3 Fracture of orbital floor
0.707 0.293 0.000
N39.2 Orthostatic proteinuria, unspecified
0.706 0.293 0.000
N39.1 Persistent proteinuria, unspecified
0.706 0.293 0.000
S01.3 Open wound of ear
0.706 0.294 0.000
N37 Urethral disorders in diseases classified elsewhere
0.706 0.294 0.000
N34 Urethritis and urethral syndrome
0.706 0.294 0.000
N33 Bladder disorders in diseases classified elsewhere
0.706 0.294 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
M49 Spondylopathies in diseases classified elsewhere
0.705 0.295 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.705 0.295 0.000
H26.2 Complicated cataract
0.704 0.295 0.000
M51.2 Other specified intervertebral disk displacement
0.703 0.297 0.000
E61.1 Iron deficiency
0.701 0.299 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.701 0.299 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.701 0.299 0.000
H15 Disorders of sclera
0.701 0.299 0.000
S42 Fracture of shoulder and upper arm
0.701 0.299 0.000
S02.1 Fracture of base of skull
0.701 0.299 0.000
M53 Other dorsopathies, not elsewhere classified
0.701 0.299 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.697 0.303 0.000
H27 Other disorders of lens
0.697 0.303 0.000
M05-M14 Inflammatory polyarthropathies
0.697 0.303 0.000
N02.9 Unspecified
0.696 0.303 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.696 0.304 0.000
M48.09 Spinal stenosis (Site unspecified)
0.696 0.304 0.000
M54.50 Low back pain (Multiple sites in spine)
0.694 0.306 0.000
T79.7 Traumatic subcutaneous emphysema
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
M50.1 Cervical disk disorder with radiculopathy
0.694 0.306 0.000
H26.3 Drug-induced cataract
0.693 0.307 0.000
H26.1 Traumatic cataract
0.693 0.307 0.000
H26.0 Infantile, juvenile and presenile cataract
0.693 0.307 0.000
S72.0 Fracture of neck of femur
0.693 0.307 0.000
D55-D59 Haemolytic anaemias
0.693 0.307 0.000
S02.8 Fractures of other skull and facial bones
0.693 0.307 0.000
E04.2 Non-toxic multinodular goitre
0.692 0.308 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.692 0.308 0.000
T90 Sequelae of injuries of head
0.691 0.309 0.000
S01.9 Open wound of head, part unspecified
0.691 0.309 0.000
Chapter XXII Codes for special purposes
0.691 0.309 0.000
O00 Ectopic pregnancy
0.691 0.309 0.000
H90.2 Conductive hearing loss, unspecified
0.691 0.309 0.000
Z54 Convalescence
0.690 0.310 0.000
M23.4 Loose body in knee
0.688 0.311 0.000
M82 Osteoporosis in diseases classified elsewhere
0.688 0.312 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.688 0.312 0.000
H70 Mastoiditis and related conditions
0.688 0.312 0.000
H68 Eustachian salpingitis and obstruction
0.688 0.312 0.000
H67 Otitis media in diseases classified elsewhere
0.688 0.312 0.000
S90-S99 Injuries to the ankle and foot
0.688 0.312 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.688 0.312 0.000
D68 Other coagulation defects
0.687 0.313 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.687 0.313 0.000
H54.0 Blindness, both eyes
0.687 0.313 0.000
Y84.6 Urinary catheterisation
0.686 0.314 0.000
Z44 Fitting and adjustment of external prosthetic device
0.686 0.314 0.000
Y57 Other and unspecified drugs and medicaments
0.685 0.315 0.000
H61.2 Impacted cerumen
0.685 0.315 0.000
Q50-Q56 Congenital malformations of genital organs
0.685 0.315 0.000
S41 Open wound of shoulder and upper arm
0.685 0.315 0.000
W55 Bitten or struck by other mammals
0.685 0.315 0.000
M47.1 Other spondylosis with myelopathy
0.685 0.315 0.000
H18.9 Disorder of cornea, unspecified
0.685 0.315 0.000
T51 Toxic effect of alcohol
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
S51 Open wound of forearm
0.683 0.317 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.683 0.317 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.683 0.317 0.000
Z41.3 Ear piercing
0.683 0.317 0.000
Z41.2 Routine and ritual circumcision
0.683 0.317 0.000
Z41.0 Hair transplant
0.683 0.317 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.683 0.317 0.000
D74 Methaemoglobinaemia
0.683 0.317 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.683 0.317 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.683 0.317 0.000
M50.9 Cervical disk disorder, unspecified
0.682 0.318 0.000
M50.8 Other cervical disk disorders
0.682 0.318 0.000
E24 Cushing's syndrome
0.682 0.318 0.000
Z50.6 Orthoptic training
0.682 0.318 0.000
Z50.3 Drug rehabilitation
0.682 0.318 0.000
D72 Other disorders of white blood cells
0.681 0.319 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.680 0.320 0.000
H72 Perforation of tympanic membrane
0.680 0.320 0.000
E40-E46 Malnutrition
0.680 0.320 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.679 0.321 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.679 0.321 0.000
H74.0 Tympanosclerosis
0.679 0.321 0.000
N35 Urethral stricture
0.677 0.323 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.677 0.323 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.674 0.326 0.000
H54.9 Unspecified visual impairment (binocular)
0.674 0.326 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.674 0.326 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.673 0.326 0.000
H01 Other inflammation of eyelid
0.673 0.327 0.000
H40-H42 Glaucoma
0.672 0.328 0.000
M84.03 Malunion of fracture (Forearm)
0.672 0.328 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.672 0.328 0.000
V80-V89 Other land transport accidents
0.671 0.328 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.670 0.330 0.000
E00 Congenital iodine-deficiency syndrome
0.670 0.330 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.670 0.330 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.670 0.330 0.000
S02.7 Multiple fractures involving skull and facial bones
0.670 0.330 0.000
S02.0 Fracture of vault of skull
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.669 0.331 0.000
H10-H13 Disorders of conjunctiva
0.669 0.331 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.669 0.331 0.000
N25-N29 Other disorders of kidney and ureter
0.669 0.331 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.668 0.332 0.000
M35 Other systemic involvement of connective tissue
0.668 0.332 0.000
M34 Systemic sclerosis
0.668 0.332 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.667 0.333 0.000
M83 Adult osteomalacia
0.665 0.334 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.665 0.335 0.000
Z45 Adjustment and management of implanted device
0.665 0.335 0.000
H21.8 Other specified disorders of iris and ciliary body
0.664 0.336 0.000
T92 Sequelae of injuries of upper limb
0.664 0.336 0.000
M54.9 Dorsalgia, unspecified
0.663 0.337 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.662 0.338 0.000
S61 Open wound of wrist and hand
0.662 0.338 0.000
O85-O92 Complications predominantly related to the puerperium
0.662 0.338 0.000
H43 Disorders of vitreous body
0.661 0.339 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.661 0.339 0.000
M20 Acquired deformities of fingers and toes
0.661 0.339 0.000
M85 Other disorders of bone density and structure
0.660 0.340 0.000
M54.55 Low back pain (Thoracolumbar region)
0.659 0.340 0.000
M54.54 Low back pain-Thoracic
0.659 0.340 0.000
M54.53 Low back pain-Cervicothoracic
0.659 0.340 0.000
M54.52 Low back pain-Cervical
0.659 0.340 0.000
M54.51 Low back pain-Occipit-atl-axl
0.659 0.340 0.000
M54.2 Cervicalgia
0.659 0.341 0.000
Y43 Primarily systemic agents
0.659 0.341 0.000
N75 Diseases of Bartholin's gland
0.659 0.341 0.000
S06.9 Intracranial injury, unspecified
0.658 0.342 0.000
S06.8 Other intracranial injuries
0.658 0.342 0.000
S06.7 Intracranial injury with prolonged coma
0.658 0.342 0.000
S06.4 Epidural haemorrhage
0.658 0.342 0.000
S06.1 Traumatic cerebral oedema
0.658 0.342 0.000
S06.0 Concussion
0.658 0.342 0.000
H04.1 Other disorders of lachrymal gland
0.658 0.342 0.000
M48.9 Spondylopathy, unspecified
0.657 0.342 0.000
M48.8 Other specified spondylopathies
0.657 0.342 0.000
M48.4 Fatigue fracture of vertebra
0.657 0.342 0.000
M48.3 Traumatic spondylopathy
0.657 0.342 0.000
M48.2 Kissing spine
0.657 0.342 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.657 0.342 0.000
Y86 Sequelae of other accidents
0.657 0.343 0.000
H18.5 Hereditary corneal dystrophies
0.657 0.343 0.000
S02.4 Fracture of malar and maxillary bones
0.657 0.343 0.000
S01.1 Open wound of eyelid and periocular area
0.656 0.344 0.000
S01.4 Open wound of cheek and temporomandibular area
0.656 0.344 0.000
N30.0 Acute cystitis
0.655 0.345 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.655 0.345 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.655 0.345 0.000
S20 Superficial injury of thorax
0.655 0.345 0.000
H18.8 Other specified disorders of cornea
0.654 0.346 0.000
H61.0 Perichondritis of external ear
0.654 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.652 0.348 0.000
H66 Suppurative and unspecified otitis media
0.651 0.348 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.651 0.349 0.000
E14 Unspecified diabetes mellitus
0.651 0.349 0.000
H65.2 Chronic serous otitis media
0.651 0.349 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.651 0.349 0.000
M54.37 Sciatica (Lumbosacral region)
0.650 0.350 0.000
G52 Disorders of other cranial nerves
0.649 0.350 0.000
Z43.2 Attention to ileostomy
0.649 0.351 0.000
H20.8 Other iridocyclitis
0.649 0.351 0.000
H20.2 Lens-induced iridocyclitis
0.649 0.351 0.000
H20.1 Chronic iridocyclitis
0.649 0.351 0.000
D80-D89 Certain disorders involving the immune mechanism
0.649 0.351 0.000
N10-N16 Renal tubulo-interstitial diseases
0.648 0.352 0.000
S78 Traumatic amputation of hip and thigh
0.647 0.353 0.000
S77 Crushing injury of hip and thigh
0.647 0.353 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.647 0.353 0.000
S75 Injury of blood vessels at hip and thigh level
0.647 0.353 0.000
S74 Injury of nerves at hip and thigh level
0.647 0.353 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.647 0.353 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.647 0.353 0.000
Y59 Other and unspecified vaccines and biological substances
0.647 0.353 0.000
Y58 Bacterial vaccines
0.647 0.353 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.647 0.353 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.647 0.353 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.647 0.353 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.647 0.353 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.647 0.353 0.000
Y48 Anaesthetics and therapeutic gases
0.647 0.353 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.647 0.353 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.647 0.353 0.000
Z50.2 Alcohol rehabilitation
0.646 0.354 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.645 0.355 0.000
D73.9 Disease of spleen, unspecified
0.644 0.356 0.000
D73.8 Other diseases of spleen
0.644 0.356 0.000
D73.4 Cyst of spleen
0.644 0.356 0.000
D73.3 Abscess of spleen
0.644 0.356 0.000
D73.2 Chronic congestive splenomegaly
0.644 0.356 0.000
D73.1 Hypersplenism
0.644 0.356 0.000
H92 Otalgia and effusion of ear
0.644 0.356 0.000
Z49 Care involving dialysis
0.644 0.356 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.643 0.356 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.643 0.356 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.643 0.356 0.000
M54.44 Lumbago with sciatica-Thoracic
0.643 0.356 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.643 0.356 0.000
M54.42 Lumbago with sciatica-Cervical
0.643 0.356 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.643 0.356 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.643 0.356 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.643 0.357 0.000
E03 Other hypothyroidism
0.642 0.358 0.000
B35-B49 Mycoses
0.641 0.359 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.640 0.359 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.640 0.359 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.640 0.359 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.640 0.359 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.640 0.359 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.640 0.359 0.000
T36 Poisoning by systemic antibiotics
0.640 0.359 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.640 0.360 0.000
N70 Salpingitis and oophoritis
0.640 0.360 0.000
M23.3 Other meniscus derangements
0.640 0.360 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.639 0.360 0.000
E34 Other endocrine disorders
0.639 0.360 0.000
E32 Diseases of thymus
0.639 0.360 0.000
E31 Polyglandular dysfunction
0.639 0.360 0.000
E30 Disorders of puberty, not elsewhere classified
0.639 0.360 0.000
E26 Hyperaldosteronism
0.639 0.360 0.000
E25 Adrenogenital disorders
0.639 0.360 0.000
E20 Hypoparathyroidism
0.639 0.360 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.638 0.362 0.000
M66 Spontaneous rupture of synovium and tendon
0.638 0.362 0.000
T66-T78 Other and unspecified effects of external causes
0.638 0.362 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.638 0.362 0.000
T91 Sequelae of injuries of neck and trunk
0.637 0.362 0.000
D50-D53 Nutritional anaemias
0.637 0.363 0.000
M54.39 Sciatica (Site unspecified)
0.637 0.363 0.000
H17.9 Corneal scar and opacity, unspecified
0.636 0.363 0.000
M23.1 Discoid meniscus (congenital)
0.635 0.365 0.000
S72.4 Fracture of lower end of femur
0.634 0.366 0.000
N39.4 Other specified urinary incontinence
0.634 0.366 0.000
H33 Retinal detachments and breaks
0.633 0.367 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.632 0.368 0.000
E06.9 Thyroiditis, unspecified
0.632 0.368 0.000
S62 Fracture at wrist and hand level
0.631 0.369 0.000
Y40 Systemic antibiotics
0.631 0.369 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.630 0.370 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.630 0.370 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.630 0.370 0.000
O07 Failed attempted abortion
0.630 0.370 0.000
O06 Unspecified abortion
0.630 0.370 0.000
O05 Other abortion
0.630 0.370 0.000
O01 Hydatidiform mole
0.630 0.370 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.629 0.370 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.629 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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