TreeWAS – Variant ID: rs11223581

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.018	0.982	0.000
T39.1 4-Aminophenol derivatives	0.017	0.982	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.017	0.983	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.017	0.983	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
T43.2 Other and unspecified antidepressants	0.016	0.984	0.000
T39.0 Salicylates	0.015	0.985	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.015	0.985	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.014	0.986	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.013	0.986	0.000
T39.4 Antirheumatics, not elsewhere classified	0.013	0.986	0.000
T39.2 Pyrazolone derivatives	0.013	0.986	0.000
T40.2 Other opioids	0.013	0.987	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.013	0.987	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.013	0.987	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.013	0.987	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.013	0.987	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.012	0.988	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.012	0.988	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.012	0.988	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.012	0.988	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.012	0.988	0.000
T36 Poisoning by systemic antibiotics	0.012	0.988	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.012	0.988	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.988	0.000
M25.5 Pain in joint	0.012	0.988	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
T43.6 Psychostimulants with abuse potential	0.012	0.988	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.012	0.988	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.011	0.988	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.011	0.989	0.000
C67.9 Bladder, unspecified	0.011	0.989	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.011	0.989	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.010	0.989	0.000
T40.8 Lysergide [LSD]	0.010	0.989	0.000
T40.7 Cannabis (derivatives)	0.010	0.989	0.000
T40.6 Other and unspecified narcotics	0.010	0.989	0.000
T40.5 Cocaine	0.010	0.989	0.000
T40.3 Methadone	0.010	0.989	0.000
T40.1 Heroin	0.010	0.989	0.000
T40.0 Opium	0.010	0.989	0.000
T42.4 Benzodiazepines	0.011	0.989	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.011	0.989	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.010	0.990	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
M25.54 Pain in joint (Hand)	0.010	0.990	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.010	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.010	0.990	0.000
T46.7 Peripheral vasodilators	0.010	0.990	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.010	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.010	0.990	0.000
T46.1 Calcium-channel blockers	0.010	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.010	0.990	0.000
T40.4 Other synthetic narcotics	0.009	0.990	0.000
M25.59 Pain in joint (Site unspecified)	0.010	0.990	0.000
T38.9 Other and unspecified hormone antagonists	0.009	0.990	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.990	0.000
T38.7 Androgens and anabolic congeners	0.009	0.990	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.009	0.990	0.000
T38.5 Other oestrogens and progestogens	0.009	0.990	0.000
T38.4 Oral contraceptives	0.009	0.990	0.000
T38.2 Antithyroid drugs	0.009	0.990	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.990	0.000
T38.0 Glucocorticoids and synthetic analogues	0.009	0.990	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.009	0.991	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.009	0.991	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.009	0.991	0.000
T42.3 Barbiturates	0.009	0.991	0.000
T42.2 Succinimides and oxazolidinediones	0.009	0.991	0.000
T42.1 Iminostilbenes	0.009	0.991	0.000
T42.0 Hydantoin derivatives	0.009	0.991	0.000
T50.8 Diagnostic agents	0.009	0.991	0.000
T50.7 Analeptics and opioid receptor antagonists	0.009	0.991	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.991	0.000
T50.5 Appetite depressants	0.009	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.009	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.009	0.991	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.009	0.991	0.000
M25.58 Pain in joint (Other)	0.009	0.991	0.000
M25.52 Pain in joint (Upper arm)	0.009	0.991	0.000
M25.53 Pain in joint (Forearm)	0.009	0.991	0.000
T36.9 Systemic antibiotic, unspecified	0.009	0.991	0.000
T36.8 Other systemic antibiotics	0.009	0.991	0.000
T36.7 Antifungal antibiotics, systemically used	0.009	0.991	0.000
T36.6 Rifamycins	0.009	0.991	0.000
T36.5 Aminoglycosides	0.009	0.991	0.000
T36.4 Tetracyclines	0.009	0.991	0.000
T36.3 Macrolides	0.009	0.991	0.000
T36.2 Chloramphenicol group	0.009	0.991	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.009	0.991	0.000
T36.0 Penicillins	0.009	0.991	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T37.5 Antiviral drugs	0.009	0.991	0.000
T37.4 Anthelminthics	0.009	0.991	0.000
T37.3 Other antiprotozoal drugs	0.009	0.991	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.009	0.991	0.000
T37.1 Antimycobacterial drugs	0.009	0.991	0.000
T37.0 Sulphonamides	0.009	0.991	0.000
T41.5 Therapeutic gases	0.009	0.991	0.000
T41.4 Anaesthetic, unspecified	0.009	0.991	0.000
T41.3 Local anaesthetics	0.009	0.991	0.000
T41.2 Other and unspecified general anaesthetics	0.009	0.991	0.000
T41.1 Intravenous anaesthetics	0.009	0.991	0.000
T41.0 Inhaled anaesthetics	0.009	0.991	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.009	0.991	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
T47.7 Emetics	0.009	0.991	0.000
T47.6 Antidiarrhoeal drugs	0.009	0.991	0.000
T47.5 Digestants	0.009	0.991	0.000
T47.4 Other laxatives	0.009	0.991	0.000
T47.3 Saline and osmotic laxatives	0.009	0.991	0.000
T47.2 Stimulant laxatives	0.009	0.991	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.009	0.991	0.000
T47.0 Histamine H(2)-receptor antagonists	0.009	0.991	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.009	0.991	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.009	0.991	0.000
T48.5 Anti-common-cold drugs	0.009	0.991	0.000
T48.4 Expectorants	0.009	0.991	0.000
T48.3 Antitussives	0.009	0.991	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.009	0.991	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.009	0.991	0.000
T48.0 Oxytocic drugs	0.009	0.991	0.000
T49.9 Topical agent, unspecified	0.009	0.991	0.000
T49.8 Other topical agents	0.009	0.991	0.000
T49.7 Dental drugs, topically applied	0.009	0.991	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.009	0.991	0.000
T49.5 Ophthalmological drugs and preparations	0.009	0.991	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.009	0.991	0.000
T49.3 Emollients, demulcents and protectants	0.009	0.991	0.000
T49.2 Local astringents and local detergents	0.009	0.991	0.000
T49.1 Antipruritics	0.009	0.991	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.009	0.991	0.000
C67 Malignant neoplasm of bladder	0.009	0.991	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.009	0.991	0.000
T45.8 Other primarily systemic and haematological agents	0.009	0.991	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.009	0.991	0.000
T45.6 Fibrinolysis-affecting drugs	0.009	0.991	0.000
T45.5 Anticoagulants	0.009	0.991	0.000
T45.4 Iron and its compounds	0.009	0.991	0.000
T45.3 Enzymes, not elsewhere classified	0.009	0.991	0.000
T45.2 Vitamins, not elsewhere classified	0.009	0.991	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.009	0.991	0.000
M25.51 Pain in joint (Shoulder region)	0.009	0.991	0.000
T45.0 Antiallergic and antiemetic drugs	0.009	0.991	0.000
M25.50 Pain in joint (Multiple sites)	0.009	0.991	0.000
C67.5 Bladder neck	0.009	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.008	0.992	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.008	0.992	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.008	0.992	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.008	0.992	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.008	0.992	0.000
T44.0 Anticholinesterase agents	0.008	0.992	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.008	0.992	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.008	0.992	0.000
M25.57 Pain in joint (Ankle and foot)	0.007	0.992	0.000
C67.3 Anterior wall of bladder	0.007	0.992	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.992	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.007	0.993	0.000
C67.4 Posterior wall of bladder	0.007	0.993	0.000
C67.2 Lateral wall of bladder	0.007	0.993	0.000
C67.1 Dome of bladder	0.007	0.993	0.000
C67.8 Overlapping lesion of bladder	0.007	0.993	0.000
C67.7 Urachus	0.007	0.993	0.000
C67.0 Trigone of bladder	0.007	0.993	0.000
D05.1 Intraductal carcinoma in situ	0.006	0.994	0.000
G45.3 Amaurosis fugax	0.006	0.994	0.000
C67.6 Ureteric orifice	0.006	0.994	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.006	0.994	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.006	0.994	0.000
G45.0 Vertebro-basilar artery syndrome	0.006	0.994	0.000
G45.4 Transient global amnesia	0.005	0.994	0.000
M25.56 Pain in joint (Lower leg)	0.005	0.995	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.000	0.995	0.005
G47.9 Sleep disorder, unspecified	0.005	0.995	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.000	0.995	0.005
M19.99 Arthrosis, unspecified (Site unspecified)	0.004	0.996	0.000
G47 Sleep disorders	0.004	0.996	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.003	0.997	0.000
M19.0 Primary arthrosis of other joints	0.003	0.997	0.000
G40-G47 Episodic and paroxysmal disorders	0.003	0.997	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.003	0.997	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.003	0.997	0.000
M25 Other joint disorders, not elsewhere classified	0.003	0.997	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
G47.8 Other sleep disorders	0.003	0.997	0.000
G47.4 Narcolepsy and cataplexy	0.003	0.997	0.000
G47.2 Disorders of the sleep-wake schedule	0.003	0.997	0.000
M16.9 Coxarthrosis, unspecified	0.003	0.997	0.000
G44 Other headache syndromes	0.003	0.997	0.000
D05 Carcinoma in situ of breast	0.003	0.997	0.000
M19.08 Primary arthrosis of other joints (Other)	0.003	0.997	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.003	0.997	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.003	0.997	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.003	0.997	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.003	0.997	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.003	0.997	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.003	0.997	0.000
M25.0 Haemarthrosis	0.003	0.997	0.000
M19 Other arthrosis	0.003	0.997	0.000
G41 Status epilepticus	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
N60.0 Solitary cyst of breast	0.003	0.997	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.997	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.002	0.997	0.000
M25.4 Effusion of joint	0.003	0.997	0.000
M25.3 Other instability of joint	0.002	0.997	0.000
M25.2 Flail joint	0.002	0.997	0.000
M25.1 Fistula of joint	0.002	0.997	0.000
M16 Coxarthrosis [arthrosis of hip]	0.003	0.997	0.000
M25.9 Joint disorder, unspecified	0.002	0.997	0.000
M25.8 Other specified joint disorders	0.002	0.997	0.000
C64-C68 Malignant neoplasms of urinary tract	0.002	0.997	0.000
M18 Arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M15-M19 Arthrosis	0.002	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
Y43.3 Other antineoplastic drugs	0.002	0.998	0.000
M19.1 Posttraumatic arthrosis of other joints	0.002	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.002	0.998	0.000
G44.8 Other specified headache syndromes	0.002	0.998	0.000
G44.3 Chronic posttraumatic headache	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
D05.7 Other carcinoma in situ of breast	0.002	0.998	0.000
M16.5 Other posttraumatic coxarthrosis	0.002	0.998	0.000
N20.0 Calculus of kidney	0.002	0.998	0.000
N64.8 Other specified disorders of breast	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.002	0.998	0.000
G46.7 Other lacunar syndromes	0.002	0.998	0.000
G46.6 Pure sensory lacunar syndrome	0.002	0.998	0.000
G46.5 Pure motor lacunar syndrome	0.002	0.998	0.000
G46.4 Cerebellar stroke syndrome	0.002	0.998	0.000
G46.3 Brain stem stroke syndrome	0.002	0.998	0.000
G46.2 Posterior cerebral artery syndrome	0.002	0.998	0.000
G46.1 Anterior cerebral artery syndrome	0.002	0.998	0.000
G46.0 Middle cerebral artery syndrome	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.002	0.998	0.000
M25.09 Haemarthrosis (Site unspecified)	0.002	0.998	0.000
M25.08 Haemarthrosis (Other)	0.002	0.998	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.002	0.998	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M25.04 Haemarthrosis (Hand)	0.002	0.998	0.000
M25.03 Haemarthrosis (Forearm)	0.002	0.998	0.000
M25.02 Haemarthrosis (Upper arm)	0.002	0.998	0.000
M25.01 Haemarthrosis (Shoulder region)	0.002	0.998	0.000
M25.00 Haemarthrosis (Multiple sites)	0.002	0.998	0.000
M19.8 Other specified arthrosis	0.002	0.998	0.000
M19.2 Other secondary arthrosis	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
M16.3 Other dysplastic coxarthrosis	0.002	0.998	0.000
M17.1 Other primary gonarthrosis	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
G41.8 Other status epilepticus	0.002	0.998	0.000
G41.2 Complex partial status epilepticus	0.002	0.998	0.000
G41.1 Petit mal status epilepticus	0.002	0.998	0.000
G41.0 Grand mal status epilepticus	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
M25.19 Fistula of joint (Site unspecified)	0.002	0.998	0.000
M25.18 Fistula of joint (Other)	0.002	0.998	0.000
M25.17 Fistula of joint (Ankle and foot)	0.002	0.998	0.000
M25.16 Fistula of joint (Lower leg)	0.002	0.998	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.14 Fistula of joint (Hand)	0.002	0.998	0.000
M25.13 Fistula of joint (Forearm)	0.002	0.998	0.000
M25.12 Fistula of joint (Upper arm)	0.002	0.998	0.000
M25.11 Fistula of joint (Shoulder region)	0.002	0.998	0.000
M25.10 Fistula of joint (Multiple sites)	0.002	0.998	0.000
M25.29 Flail joint (Site unspecified)	0.002	0.998	0.000
M25.28 Flail joint (Other)	0.002	0.998	0.000
M25.27 Flail joint (Ankle and foot)	0.002	0.998	0.000
M25.26 Flail joint (Lower leg)	0.002	0.998	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.24 Flail joint (Hand)	0.002	0.998	0.000
M25.23 Flail joint (Forearm)	0.002	0.998	0.000
M25.22 Flail joint (Upper arm)	0.002	0.998	0.000
M25.21 Flail joint (Shoulder region)	0.002	0.998	0.000
M25.20 Flail joint (Multiple sites)	0.002	0.998	0.000
M25.39 Other instability of joint (Site unspecified)	0.002	0.998	0.000
M25.38 Other instability of joint (Other)	0.002	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
M25.36 Other instability of joint (Lower leg)	0.002	0.998	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.34 Other instability of joint (Hand)	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.998	0.000
M25.31 Other instability of joint (Shoulder region)	0.002	0.998	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.998	0.000
G41.9 Status epilepticus, unspecified	0.002	0.998	0.000
Y84.8 Other medical procedures	0.000	0.998	0.002
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.002	0.998	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.002	0.998	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.002	0.998	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.002	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.998	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.002	0.998	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.002	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M15 Polyarthrosis	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.002	0.998	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.002	0.998	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.002	0.998	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.002	0.998	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.002	0.998	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.002	0.998	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.002	0.998	0.000
G44.2 Tension-type headache	0.002	0.998	0.000
M16.7 Other secondary coxarthrosis	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.002	0.998	0.000
M16.1 Other primary coxarthrosis	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
M17 Gonarthrosis [arthrosis of knee]	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.002	0.998	0.000
M19.28 Other secondary arthrosis (Other)	0.002	0.998	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.002	0.998	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.24 Other secondary arthrosis (Hand)	0.002	0.998	0.000
M19.23 Other secondary arthrosis (Forearm)	0.002	0.998	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.002	0.998	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.002	0.998	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.002	0.998	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.002	0.998	0.000
M19.88 Other specified arthrosis (Other)	0.002	0.998	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.002	0.998	0.000
M19.86 Other specified arthrosis (Lower leg)	0.002	0.998	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.84 Other specified arthrosis (Hand)	0.002	0.998	0.000
M19.83 Other specified arthrosis (Forearm)	0.002	0.998	0.000
M19.82 Other specified arthrosis (Upper arm)	0.002	0.998	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.002	0.998	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
B34.9 Viral infection, unspecified	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
C68.9 Urinary organ, unspecified	0.002	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.002	0.998	0.000
C68.1 Paraurethral glands	0.002	0.998	0.000
C68.0 Urethra	0.002	0.998	0.000
Y84.0 Cardiac catheterisation	0.002	0.998	0.000
G40 Epilepsy	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
M15.9 Polyarthrosis, unspecified	0.001	0.998	0.000
M15.0 Primary generalised (osteo)arthrosis	0.001	0.998	0.000
M15.8 Other polyarthrosis	0.001	0.998	0.000
M15.4 Erosive (osteo)arthrosis	0.001	0.998	0.000
M15.3 Secondary multiple arthrosis	0.001	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.001	0.998	0.000
M15.1 Heberden's nodes (with arthropathy)	0.001	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
N60 Benign mammary dysplasia	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.002
M54.47 Lumbago with sciatica (Lumbosacral region)	0.002	0.998	0.000
J35.1 Hypertrophy of tonsils	0.002	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
M17.5 Other secondary gonarthrosis	0.002	0.998	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.002	0.998	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.002	0.998	0.000
M17.0 Primary gonarthrosis, bilateral	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.001	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.998	0.000
N64 Other disorders of breast	0.002	0.998	0.000
N60.3 Fibrosclerosis of breast	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
G40.8 Other epilepsy	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
Z50.1 Other physical therapy	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
N64.9 Disorder of breast, unspecified	0.002	0.998	0.000
T33-T35 Frostbite	0.001	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.998	0.000
T00-T07 Injuries involving multiple body regions	0.001	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.001	0.998	0.000
S32.3 Fracture of ilium	0.001	0.998	0.000
S32.2 Fracture of coccyx	0.001	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.001	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.001	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.001	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.001	0.998	0.000
Y43.2 Antineoplastic natural products	0.001	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.001	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
Z45.2 Adjustment and management of vascular access device	0.002	0.998	0.000
T58 Toxic effect of carbon monoxide	0.001	0.998	0.000
M17.3 Other posttraumatic gonarthrosis	0.001	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.001	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.001	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.001	0.998	0.000
M19.9 Arthrosis, unspecified	0.002	0.998	0.000
S81.0 Open wound of knee	0.001	0.998	0.000
S92.3 Fracture of metatarsal bone	0.001	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.001	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.998	0.000
T75 Effects of other external causes	0.001	0.998	0.000
T74 Maltreatment syndromes	0.001	0.998	0.000
T73 Effects of other deprivation	0.001	0.998	0.000
T70 Effects of air pressure and water pressure	0.001	0.998	0.000
T69 Other effects of reduced temperature	0.001	0.998	0.000
T67 Effects of heat and light	0.001	0.998	0.000
T71 Asphyxiation	0.001	0.998	0.000
T68 Hypothermia	0.001	0.998	0.000
T66 Unspecified effects of radiation	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations