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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112448655
log Bayes Factor = 0.123616
Chromosome 3   position 139,811,629  (GRCh37) Explore rs112448655 on Ensembl!
Variant rs112448655 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M19.9 Arthrosis, unspecified
0.260 0.740 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.256 0.744 0.000
M19 Other arthrosis
0.255 0.745 0.000
M16 Coxarthrosis [arthrosis of hip]
0.248 0.752 0.000
M15-M19 Arthrosis
0.245 0.755 0.000
M16.0 Primary coxarthrosis, bilateral
0.242 0.758 0.000
M16.9 Coxarthrosis, unspecified
0.227 0.773 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.224 0.776 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.214 0.786 0.000
M19.1 Posttraumatic arthrosis of other joints
0.208 0.792 0.000
M19.0 Primary arthrosis of other joints
0.203 0.797 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.199 0.801 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.196 0.803 0.000
M16.1 Other primary coxarthrosis
0.195 0.805 0.000
M19.94 Arthrosis, unspecified (Hand)
0.195 0.805 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.190 0.810 0.000
M19.98 Arthrosis, unspecified (Other)
0.186 0.813 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.186 0.813 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.186 0.813 0.000
M19.8 Other specified arthrosis
0.183 0.817 0.000
M19.2 Other secondary arthrosis
0.183 0.817 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.181 0.819 0.000
M16.7 Other secondary coxarthrosis
0.178 0.822 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.178 0.822 0.000
M16.5 Other posttraumatic coxarthrosis
0.178 0.822 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.178 0.822 0.000
M16.3 Other dysplastic coxarthrosis
0.178 0.822 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.178 0.822 0.000
M15 Polyarthrosis
0.176 0.824 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.174 0.826 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.164 0.836 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.151 0.849 0.000
M05-M14 Inflammatory polyarthropathies
0.151 0.849 0.000
M18 Arthrosis of first carpometacarpal joint
0.150 0.850 0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)
0.149 0.851 0.000
M19.18 Post-traumatic arthrosis of other joints (Other)
0.149 0.851 0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg
0.149 0.851 0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)
0.149 0.851 0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)
0.149 0.851 0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)
0.149 0.851 0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)
0.149 0.851 0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)
0.149 0.851 0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)
0.149 0.851 0.000
M20-M25 Other joint disorders
0.149 0.851 0.000
M65-M68 Disorders of synovium and tendon
0.146 0.854 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.145 0.855 0.000
M19.08 Primary arthrosis of other joints (Other)
0.145 0.855 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.145 0.855 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.145 0.855 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.145 0.855 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.145 0.855 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.145 0.855 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.141 0.859 0.000
M20 Acquired deformities of fingers and toes
0.136 0.864 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.136 0.864 0.000
M70-M79 Other soft tissue disorders
0.135 0.865 0.000
M91-M94 Chondropathies
0.134 0.866 0.000
M86-M90 Other osteopathies
0.134 0.866 0.000
M80-M85 Disorders of bone density and structure
0.134 0.866 0.000
M20.4 Other hammer toe(s) (acquired)
0.131 0.869 0.000
M19.29 Other secondary arthrosis (Site unspecified)
0.131 0.869 0.000
M19.28 Other secondary arthrosis (Other)
0.131 0.869 0.000
M19.27 Other secondary arthrosis (Ankle and foot)
0.131 0.869 0.000
M19.26 Other secondary arthrosis of other joints-Lower leg
0.131 0.869 0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)
0.131 0.869 0.000
M19.24 Other secondary arthrosis (Hand)
0.131 0.869 0.000
M19.23 Other secondary arthrosis (Forearm)
0.131 0.869 0.000
M19.22 Other secondary arthrosis (Upper arm)
0.131 0.869 0.000
M19.21 Other secondary arthrosis (Shoulder region)
0.131 0.869 0.000
M19.20 Other secondary arthrosis (Multiple sites)
0.131 0.869 0.000
M19.89 Other specified arthrosis (Site unspecified)
0.131 0.869 0.000
M19.88 Other specified arthrosis (Other)
0.131 0.869 0.000
M19.87 Other specified arthrosis (Ankle and foot)
0.131 0.869 0.000
M19.86 Other specified arthrosis (Lower leg)
0.131 0.869 0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)
0.131 0.869 0.000
M19.84 Other specified arthrosis (Hand)
0.131 0.869 0.000
M19.83 Other specified arthrosis (Forearm)
0.131 0.869 0.000
M19.82 Other specified arthrosis (Upper arm)
0.131 0.869 0.000
M19.81 Other specified arthrosis (Shoulder region)
0.131 0.869 0.000
M19.80 Other specified arthrosis (Multiple sites)
0.131 0.869 0.000
M10 Gout
0.131 0.869 0.000
M60-M63 Disorders of muscles
0.130 0.870 0.000
M00-M03 Infectious arthropathies
0.130 0.870 0.000
M40-M43 Deforming dorsopathies
0.128 0.871 0.000
M15.9 Polyarthrosis, unspecified
0.126 0.874 0.000
M15.0 Primary generalised (osteo)arthrosis
0.126 0.874 0.000
M15.8 Other polyarthrosis
0.126 0.874 0.000
M15.4 Erosive (osteo)arthrosis
0.126 0.874 0.000
M15.3 Secondary multiple arthrosis
0.126 0.874 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.126 0.874 0.000
M15.1 Heberden's nodes (with arthropathy)
0.126 0.874 0.000
M45-M49 Spondylopathies
0.126 0.874 0.000
M21 Other acquired deformities of limbs
0.125 0.875 0.000
M10.9 Gout, unspecified
0.117 0.883 0.000
M22 Disorders of patella
0.115 0.885 0.000
M13 Other arthritis
0.114 0.886 0.000
M65 Synovitis and tenosynovitis
0.114 0.886 0.000
M67 Other disorders of synovium and tendon
0.114 0.886 0.000
M77 Other enthesopathies
0.110 0.890 0.000
M35 Other systemic involvement of connective tissue
0.109 0.891 0.000
M14 Arthropathies in other diseases classified elsewhere
0.108 0.892 0.000
M12 Other specific arthropathies
0.108 0.892 0.000
M11 Other crystal arthropathies
0.108 0.892 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.108 0.892 0.000
M08 Juvenile arthritis
0.108 0.892 0.000
M07 Psoriatic and enteropathic arthropathies
0.108 0.892 0.000
M05 Seropositive rheumatoid arthritis
0.108 0.892 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.108 0.892 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.108 0.892 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.108 0.892 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.108 0.892 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.108 0.892 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.108 0.892 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.107 0.893 0.000
M34 Systemic sclerosis
0.107 0.893 0.000
M33 Dermatopolymyositis
0.107 0.893 0.000
M32 Systemic lupus erythematosus
0.107 0.893 0.000
M31 Other necrotising vasculopathies
0.107 0.893 0.000
M30 Polyarteritis nodosa and related conditions
0.107 0.893 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.106 0.894 0.000
M10.99 Gout, unspecified (Site unspecified)
0.106 0.894 0.000
M20.3 Other deformity of hallux (acquired)
0.105 0.895 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.105 0.895 0.000
M66 Spontaneous rupture of synovium and tendon
0.105 0.895 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.104 0.895 0.000
M21.2 Flexion deformity
0.104 0.896 0.000
M84 Disorders of continuity of bone
0.104 0.896 0.000
M20.5 Other deformities of toe(s) (acquired)
0.101 0.899 0.000
M94 Other disorders of cartilage
0.101 0.899 0.000
M45 Ankylosing spondylitis
0.101 0.899 0.000
M86 Osteomyelitis
0.100 0.900 0.000
M25 Other joint disorders, not elsewhere classified
0.100 0.900 0.000
M80 Osteoporosis with pathological fracture
0.100 0.900 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.099 0.900 0.000
M87 Osteonecrosis
0.099 0.901 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.098 0.902 0.000
M99 Biomechanical lesions, not elsewhere classified
0.098 0.902 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.098 0.902 0.000
M20.0 Deformity of finger(s)
0.098 0.902 0.000
M76 Enthesopathies of lower limb, excluding foot
0.097 0.903 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.097 0.903 0.000
M71 Other bursopathies
0.097 0.903 0.000
M93 Other osteochondropathies
0.096 0.903 0.000
M92 Other juvenile osteochondrosis
0.096 0.903 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.096 0.903 0.000
M50-M54 Other dorsopathies
0.097 0.903 0.000
M90 Osteopathies in diseases classified elsewhere
0.096 0.903 0.000
M88 Paget's disease of bone [osteitis deformans]
0.096 0.903 0.000
M06 Other rheumatoid arthritis
0.096 0.903 0.000
M85 Other disorders of bone density and structure
0.096 0.904 0.000
M83 Adult osteomalacia
0.096 0.904 0.000
M82 Osteoporosis in diseases classified elsewhere
0.096 0.904 0.000
M24 Other specific joint derangements
0.096 0.904 0.000
M41 Scoliosis
0.095 0.905 0.000
M89 Other disorders of bone
0.095 0.905 0.000
M21.1 Varus deformity, not elsewhere classified
0.094 0.905 0.000
M46 Other inflammatory spondylopathies
0.094 0.906 0.000
M10.4 Other secondary gout
0.094 0.906 0.000
M10.3 Gout due to impairment of renal function
0.094 0.906 0.000
M10.2 Drug-induced gout
0.094 0.906 0.000
M10.1 Lead-induced gout
0.094 0.906 0.000
M10.0 Idiopathic gout
0.094 0.906 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.093 0.907 0.000
M02 Reactive arthropathies
0.093 0.907 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.093 0.907 0.000
M00 Pyogenic arthritis
0.093 0.907 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.093 0.907 0.000
M62 Other disorders of muscle
0.093 0.907 0.000
M61 Calcification and ossification of muscle
0.093 0.907 0.000
M60 Myositis
0.093 0.907 0.000
M67.1 Other contracture of tendon (sheath)
0.093 0.907 0.000
M42 Spinal osteochondrosis
0.092 0.908 0.000
M40 Kyphosis and lordosis
0.092 0.908 0.000
M72 Fibroblastic disorders
0.092 0.908 0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites
0.091 0.909 0.000
M15.99 Polyosteoarthritis, unspecified
0.091 0.909 0.000
M20.1 Hallux valgus (acquired)
0.090 0.910 0.000
M49 Spondylopathies in diseases classified elsewhere
0.090 0.910 0.000
M21.24 Flexion deformity (Hand)
0.090 0.910 0.000
M77.4 Metatarsalgia
0.090 0.910 0.000
M21.9 Acquired deformity of limb, unspecified
0.089 0.910 0.000
M21.8 Other specified acquired deformities of limbs
0.089 0.910 0.000
M21.7 Unequal limb length (acquired)
0.089 0.910 0.000
M21.6 Other acquired deformities of ankle and foot
0.089 0.910 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.089 0.910 0.000
M21.4 Flat foot [pes planus] (acquired)
0.089 0.910 0.000
M21.3 Wrist or foot drop (acquired)
0.089 0.910 0.000
M21.0 Valgus deformity, not elsewhere classified
0.089 0.910 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.089 0.911 0.000
M22.2 Patellofemoral disorders
0.088 0.911 0.000
M13.9 Arthritis, unspecified
0.088 0.912 0.000
M81 Osteoporosis without pathological fracture
0.088 0.912 0.000
M43 Other deforming dorsopathies
0.088 0.912 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.087 0.913 0.000
M79.8 Other specified soft tissue disorders
0.085 0.915 0.000
M22.4 Chondromalacia patellae
0.085 0.915 0.000
M22.8 Other disorders of patella
0.084 0.916 0.000
M10.98 Gout, unspecified (Other)
0.084 0.916 0.000
M10.96 Gout, unspecified (Lower leg)
0.084 0.916 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.084 0.916 0.000
M10.94 Gout, unspecified (Hand)
0.084 0.916 0.000
M10.93 Gout, unspecified (Forearm)
0.084 0.916 0.000
M10.92 Gout, unspecified (Upper arm)
0.084 0.916 0.000
M10.91 Gout, unspecified (Shoulder region)
0.084 0.916 0.000
M10.90 Gout, unspecified (Multiple sites)
0.084 0.916 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.083 0.916 0.000
M65.3 Trigger finger
0.083 0.916 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.083 0.917 0.000
M22.1 Recurrent subluxation of patella
0.083 0.917 0.000
M22.9 Disorder of patella, unspecified
0.083 0.917 0.000
M22.3 Other derangements of patella
0.083 0.917 0.000
M22.0 Recurrent dislocation of patella
0.083 0.917 0.000
M25.5 Pain in joint
0.083 0.917 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.082 0.917 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.082 0.917 0.000
M77.1 Lateral epicondylitis
0.082 0.917 0.000
M13.8 Other specified arthritis
0.082 0.918 0.000
M13.1 Monoarthritis, not elsewhere classified
0.082 0.918 0.000
M13.0 Polyarthritis, unspecified
0.082 0.918 0.000
M65.8 Other synovitis and tenosynovitis
0.082 0.918 0.000
M65.2 Calcific tendinitis
0.082 0.918 0.000
M65.1 Other infective (teno)synovitis
0.082 0.918 0.000
M65.0 Abscess of tendon sheath
0.082 0.918 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.082 0.918 0.000
M67.4 Ganglion
0.082 0.918 0.000
M67.3 Transient synovitis
0.082 0.918 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.082 0.918 0.000
M67.0 Short Achilles tendon (acquired)
0.082 0.918 0.000
M95.0 Acquired deformity of nose
0.082 0.918 0.000
M35.0 Sicca syndrome [Sjogren]
0.081 0.919 0.000
M47 Spondylosis
0.081 0.919 0.000
M77.9 Enthesopathy, unspecified
0.079 0.921 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.079 0.921 0.000
M77.5 Other enthesopathy of foot
0.079 0.921 0.000
M77.3 Calcaneal spur
0.079 0.921 0.000
M77.2 Periarthritis of wrist
0.079 0.921 0.000
M77.0 Medial epicondylitis
0.079 0.921 0.000
M67.8 Other specified disorders of synovium and tendon
0.078 0.922 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.078 0.922 0.000
M35.8 Other specified systemic involvement of connective tissue
0.078 0.922 0.000
M35.7 Hypermobility syndrome
0.078 0.922 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.078 0.922 0.000
M35.5 Multifocal fibrosclerosis
0.078 0.922 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.078 0.922 0.000
M35.2 Behcet's disease
0.078 0.922 0.000
M35.1 Other overlap syndromes
0.078 0.922 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.078 0.922 0.000
M05.8 Other seropositive rheumatoid arthritis
0.078 0.922 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.078 0.922 0.000
M05.2 Rheumatoid vasculitis
0.078 0.922 0.000
M05.1 Rheumatoid lung disease
0.078 0.922 0.000
M05.0 Felty's syndrome
0.078 0.922 0.000
M07.6 Other enteropathic arthropathies
0.078 0.922 0.000
M07.5 Arthropathy in ulcerative colitis
0.078 0.922 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.078 0.922 0.000
M07.3 Other psoriatic arthropathies
0.078 0.922 0.000
M07.2 Psoriatic spondylitis
0.078 0.922 0.000
M07.1 Arthritis mutilans
0.078 0.922 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.078 0.922 0.000
M08.9 Juvenile arthritis, unspecified
0.078 0.922 0.000
M08.8 Other juvenile arthritis
0.078 0.922 0.000
M08.4 Pauciarticular juvenile arthritis
0.078 0.922 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.078 0.922 0.000
M08.2 Juvenile arthritis with systemic onset
0.078 0.922 0.000
M08.1 Juvenile ankylosing spondylitis
0.078 0.922 0.000
M08.0 Juvenile rheumatoid arthritis
0.078 0.922 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.078 0.922 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.078 0.922 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.078 0.922 0.000
M09.0 Juvenile arthritis in psoriasis
0.078 0.922 0.000
M11.9 Crystal arthropathy, unspecified
0.078 0.922 0.000
M11.8 Other specified crystal arthropathies
0.078 0.922 0.000
M11.2 Other chondrocalcinosis
0.078 0.922 0.000
M11.1 Familial chondrocalcinosis
0.078 0.922 0.000
M11.0 Hydroxyapatite deposition disease
0.078 0.922 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.078 0.922 0.000
M12.5 Traumatic arthropathy
0.078 0.922 0.000
M12.4 Intermittent hydrarthrosis
0.078 0.922 0.000
M12.3 Palindromic rheumatism
0.078 0.922 0.000
M12.2 Villonodular synovitis (pigmented)
0.078 0.922 0.000
M12.1 Kaschin-Beck disease
0.078 0.922 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.078 0.922 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.078 0.922 0.000
M14.6 Neuropathic arthropathy
0.078 0.922 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.078 0.922 0.000
M14.4 Arthropathy in amyloidosis
0.078 0.922 0.000
M14.3 Lipoid dermatoarthritis
0.078 0.922 0.000
M14.2 Diabetic arthropathy
0.078 0.922 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.078 0.922 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.078 0.922 0.000
M94.8 Other specified disorders of cartilage
0.077 0.923 0.000
M79.0 Rheumatism, unspecified
0.077 0.923 0.000
M79.7 Fibromyalgia
0.077 0.923 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.077 0.923 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.077 0.923 0.000
M30.2 Juvenile polyarteritis
0.077 0.923 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.077 0.923 0.000
M30.0 Polyarteritis nodosa
0.077 0.923 0.000
M31.9 Necrotising vasculopathy, unspecified
0.077 0.923 0.000
M31.8 Other specified necrotising vasculopathies
0.077 0.923 0.000
M31.7 Microscopic polyangiitis
0.077 0.923 0.000
M31.6 Other giant cell arteritis
0.077 0.923 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.077 0.923 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.077 0.923 0.000
M31.3 Wegener's granulomatosis
0.077 0.923 0.000
M31.2 Lethal midline granuloma
0.077 0.923 0.000
M31.1 Thrombotic microangiopathy
0.077 0.923 0.000
M31.0 Hypersensitivity angiitis
0.077 0.923 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.077 0.923 0.000
M32.8 Other forms of systemic lupus erythematosus
0.077 0.923 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.077 0.923 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.077 0.923 0.000
M33.9 Dermatopolymyositis, unspecified
0.077 0.923 0.000
M33.2 Polymyositis
0.077 0.923 0.000
M33.1 Other dermatomyositis
0.077 0.923 0.000
M33.0 Juvenile dermatomyositis
0.077 0.923 0.000
M34.9 Systemic sclerosis, unspecified
0.077 0.923 0.000
M34.8 Other forms of systemic sclerosis
0.077 0.923 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.077 0.923 0.000
M34.1 CR(E)ST syndrome
0.077 0.923 0.000
M34.0 Progressive systemic sclerosis
0.077 0.923 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.077 0.923 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.077 0.923 0.000
M36.3 Arthropathy in other blood disorders
0.077 0.923 0.000
M36.2 Haemophilic arthropathy
0.077 0.923 0.000
M36.1 Arthropathy in neoplastic disease
0.077 0.923 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.077 0.923 0.000
M79.9 Soft tissue disorder, unspecified
0.076 0.924 0.000
M79.5 Residual foreign body in soft tissue
0.076 0.924 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.076 0.924 0.000
M79.3 Panniculitis, unspecified
0.076 0.924 0.000
M79.2 Neuralgia and neuritis, unspecified
0.076 0.924 0.000
M79.1 Myalgia
0.076 0.924 0.000
M35.3 Polymyalgia rheumatica
0.076 0.924 0.000
M86.9 Osteomyelitis, unspecified
0.076 0.924 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.075 0.924 0.000
M66.4 Spontaneous rupture of other tendons
0.075 0.924 0.000
M66.3 Spontaneous rupture of flexor tendons
0.075 0.924 0.000
M66.2 Spontaneous rupture of extensor tendons
0.075 0.924 0.000
M66.1 Rupture of synovium
0.075 0.924 0.000
M66.0 Rupture of popliteal cyst
0.075 0.924 0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere
0.075 0.924 0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere
0.075 0.924 0.000
M48 Other spondylopathies
0.075 0.925 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.075 0.925 0.000
M79.6 Pain in limb
0.075 0.925 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.075 0.925 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.075 0.925 0.000
M95.5 Acquired deformity of pelvis
0.075 0.925 0.000
M95.4 Acquired deformity of chest and rib
0.075 0.925 0.000
M95.3 Acquired deformity of neck
0.075 0.925 0.000
M95.2 Other acquired deformity of head
0.075 0.925 0.000
M95.1 Cauliflower ear
0.075 0.925 0.000
M21.29 Flexion deformity (Site unspecified)
0.075 0.925 0.000
M21.28 Flexion deformity (Other)
0.075 0.925 0.000
M21.27 Flexion deformity (Ankle and foot)
0.075 0.925 0.000
M21.26 Flexion deformity (Lower leg)
0.075 0.925 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.075 0.925 0.000
M21.23 Flexion deformity (Forearm)
0.075 0.925 0.000
M21.22 Flexion deformity (Upper arm)
0.075 0.925 0.000
M21.21 Flexion deformity (Shoulder region)
0.075 0.925 0.000
M21.20 Flexion deformity (Multiple sites)
0.075 0.925 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.075 0.925 0.000
M84.9 Disorder of continuity of bone, unspecified
0.075 0.925 0.000
M84.8 Other disorders of continuity of bone
0.075 0.925 0.000
M84.4 Pathological fracture, not elsewhere classified
0.075 0.925 0.000
M84.3 Stress fracture, not elsewhere classified
0.075 0.925 0.000
M84.2 Delayed union of fracture
0.075 0.925 0.000
M84.0 Malunion of fracture
0.075 0.925 0.000
M70.6 Trochanteric bursitis
0.074 0.926 0.000
M06.0 Seronegative rheumatoid arthritis
0.074 0.926 0.000
M87.9 Osteonecrosis, unspecified
0.073 0.927 0.000
M51 Other intervertebral disk disorders
0.073 0.927 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.073 0.927 0.000
M94.9 Disorder of cartilage, unspecified
0.073 0.927 0.000
M94.3 Chondrolysis
0.073 0.927 0.000
M94.2 Chondromalacia
0.073 0.927 0.000
M94.1 Relapsing polychondritis
0.073 0.927 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.073 0.927 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.072 0.927 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.072 0.927 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.072 0.927 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.072 0.927 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.072 0.927 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.072 0.927 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.072 0.927 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.072 0.927 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.072 0.927 0.000
M75 Shoulder lesions
0.072 0.928 0.000
M86.8 Other osteomyelitis
0.072 0.928 0.000
M86.6 Other chronic osteomyelitis
0.072 0.928 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.072 0.928 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.072 0.928 0.000
M86.3 Chronic multifocal osteomyelitis
0.072 0.928 0.000
M86.2 Subacute osteomyelitis
0.072 0.928 0.000
M86.1 Other acute osteomyelitis
0.072 0.928 0.000
M86.0 Acute haematogenous osteomyelitis
0.072 0.928 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.072 0.928 0.000
M25.9 Joint disorder, unspecified
0.072 0.928 0.000
M25.8 Other specified joint disorders
0.072 0.928 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.072 0.928 0.000
M25.3 Other instability of joint
0.072 0.928 0.000
M25.2 Flail joint
0.072 0.928 0.000
M25.1 Fistula of joint
0.072 0.928 0.000
M25.0 Haemarthrosis
0.072 0.928 0.000
M80.8 Other osteoporosis with pathological fracture
0.071 0.928 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.071 0.928 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.071 0.928 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.071 0.928 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.071 0.928 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.071 0.928 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.071 0.928 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.071 0.928 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.071 0.928 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.071 0.928 0.000
M70.7 Other bursitis of hip
0.071 0.928 0.000
M70.5 Other bursitis of knee
0.071 0.928 0.000
M70.4 Prepatellar bursitis
0.071 0.928 0.000
M70.3 Other bursitis of elbow
0.071 0.928 0.000
M70.2 Olecranon bursitis
0.071 0.928 0.000
M70.1 Bursitis of hand
0.071 0.928 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.071 0.928 0.000
M41.9 Scoliosis, unspecified
0.071 0.928 0.000
M25.54 Pain in joint (Hand)
0.072 0.928 0.000
M87.8 Other osteonecrosis
0.071 0.929 0.000
M87.3 Other secondary osteonecrosis
0.071 0.929 0.000
M87.2 Osteonecrosis due to previous trauma
0.071 0.929 0.000
M87.1 Osteonecrosis due to drugs
0.071 0.929 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.071 0.929 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.071 0.929 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.070 0.929 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.070 0.929 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.070 0.929 0.000
M96.5 Postradiation scoliosis
0.070 0.929 0.000
M96.4 Postsurgical lordosis
0.070 0.929 0.000
M96.3 Postlaminectomy kyphosis
0.070 0.929 0.000
M96.2 Postradiation kyphosis
0.070 0.929 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.070 0.929 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.070 0.929 0.000
M99.9 Biomechanical lesion, unspecified
0.070 0.929 0.000
M99.8 Other biomechanical lesions
0.070 0.929 0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina
0.070 0.929 0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina
0.070 0.929 0.000
M99.5 Intervertebral disk stenosis of neural canal
0.070 0.929 0.000
M99.4 Connective tissue stenosis of neural canal
0.070 0.929 0.000
M99.3 Osseous stenosis of neural canal
0.070 0.929 0.000
M99.2 Subluxation stenosis of neural canal
0.070 0.929 0.000
M99.1 Subluxation complex (vertebral)
0.070 0.929 0.000
M99.0 Segmental and somatic dysfunction
0.070 0.929 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.070 0.930 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.070 0.930 0.000
M71.9 Bursopathy, unspecified
0.070 0.930 0.000
M71.8 Other specified bursopathies
0.070 0.930 0.000
M71.5 Other bursitis, not elsewhere classified
0.070 0.930 0.000
M71.4 Calcium deposit in bursa
0.070 0.930 0.000
M71.3 Other bursal cyst
0.070 0.930 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.070 0.930 0.000
M71.1 Other infective bursitis
0.070 0.930 0.000
M71.0 Abscess of bursa
0.070 0.930 0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.070 0.930 0.000
M73.1 Syphilitic bursitis
0.070 0.930 0.000
M73.0 Gonococcal bursitis
0.070 0.930 0.000
M76.9 Enthesopathy of lower limb, unspecified
0.070 0.930 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.070 0.930 0.000
M76.7 Peroneal tendinitis
0.070 0.930 0.000
M76.6 Achilles tendinitis
0.070 0.930 0.000
M76.5 Patellar tendinitis
0.070 0.930 0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]
0.070 0.930 0.000
M76.3 Iliotibial band syndrome
0.070 0.930 0.000
M76.2 Iliac crest spur
0.070 0.930 0.000
M76.1 Psoas tendinitis
0.070 0.930 0.000
M76.0 Gluteal tendinitis
0.070 0.930 0.000
M13.94 Arthritis, unspecified (Hand)
0.070 0.930 0.000
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified
0.069 0.930 0.000
M91.8 Other juvenile osteochondrosis of hip and pelvis
0.069 0.930 0.000
M91.3 Pseudocoxalgia
0.069 0.930 0.000
M91.2 Coxa plana
0.069 0.930 0.000
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]
0.069 0.930 0.000
M91.0 Juvenile osteochondrosis of pelvis
0.069 0.930 0.000
M92.5 Juvenile osteochondrosis of tibia and fibula
0.069 0.930 0.000
M92.1 Juvenile osteochondrosis of radius and ulna
0.069 0.930 0.000
M92.9 Juvenile osteochondrosis, unspecified
0.069 0.930 0.000
M92.8 Other specified juvenile osteochondrosis
0.069 0.930 0.000
M92.7 Juvenile osteochondrosis of metatarsus
0.069 0.930 0.000
M92.6 Juvenile osteochondrosis of tarsus
0.069 0.930 0.000
M92.4 Juvenile osteochondrosis of patella
0.069 0.930 0.000
M92.3 Other juvenile osteochondrosis of upper limb
0.069 0.930 0.000
M92.2 Juvenile osteochondrosis of hand
0.069 0.930 0.000
M92.0 Juvenile osteochondrosis of humerus
0.069 0.930 0.000
M93.8 Other specified osteochondropathies
0.069 0.930 0.000
M93.2 Osteochondritis dissecans
0.069 0.930 0.000
M93.9 Osteochondropathy, unspecified
0.069 0.930 0.000
M93.1 Kienbock's disease of adults
0.069 0.930 0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)
0.069 0.930 0.000
M53 Other dorsopathies, not elsewhere classified
0.069 0.930 0.000
M88.9 Paget's disease of bone, unspecified
0.069 0.930 0.000
M88.8 Paget's disease of other bones
0.069 0.930 0.000
M88.0 Paget's disease of skull
0.069 0.930 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.069 0.930 0.000
M90.7 Fracture of bone in neoplastic disease
0.069 0.930 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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