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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112765961
log Bayes Factor = 20.7661
Chromosome 20   position 17,867,605  (GRCh37) Explore rs112765961 on Ensembl!
Variant rs112765961 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.990 0.010 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.990 0.010 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.990 0.010 0.000
I60-I69 Cerebrovascular diseases
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
M05-M14 Inflammatory polyarthropathies
0.982 0.018 0.000
M23 Internal derangement of knee
0.979 0.021 0.000
Z95.1 Presence of aortocoronary bypass graft
0.977 0.023 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.977 0.023 0.000
Y43 Primarily systemic agents
0.976 0.024 0.000
L20-L30 Dermatitis and eczema
0.974 0.026 0.000
R50-R69 General symptoms and signs
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
I20 Angina pectoris
0.966 0.034 0.000
I21 Acute myocardial infarction
0.965 0.035 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.965 0.035 0.000
M23.3 Other meniscus derangements
0.963 0.037 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.959 0.041 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.955 0.045 0.000
I67 Other cerebrovascular diseases
0.952 0.048 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.951 0.049 0.000
L29 Pruritus
0.950 0.050 0.000
R55 Syncope and collapse
0.949 0.051 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.943 0.057 0.000
G40-G47 Episodic and paroxysmal disorders
0.943 0.057 0.000
Y43.3 Other antineoplastic drugs
0.939 0.061 0.000
M70-M79 Other soft tissue disorders
0.936 0.064 0.000
O47 False labour
0.935 0.065 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.930 0.070 0.000
Chapter VIII Diseases of the ear and mastoid process
0.927 0.073 0.000
I20.0 Unstable angina
0.925 0.075 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.925 0.075 0.000
R00 Abnormalities of heart beat
0.923 0.077 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.921 0.079 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.920 0.080 0.000
L29.0 Pruritus ani
0.916 0.084 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.916 0.084 0.000
M13 Other arthritis
0.915 0.085 0.000
R42 Dizziness and giddiness
0.911 0.089 0.000
M15-M19 Arthrosis
0.910 0.090 0.000
M75 Shoulder lesions
0.907 0.093 0.000
B35-B49 Mycoses
0.907 0.093 0.000
R41.3 Other amnesia
0.907 0.093 0.000
R06 Abnormalities of breathing
0.904 0.096 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.902 0.098 0.000
G40 Epilepsy
0.898 0.102 0.000
L40-L45 Papulosquamous disorders
0.896 0.104 0.000
I25.2 Old myocardial infarction
0.892 0.108 0.000
Z97 Presence of other devices
0.891 0.109 0.000
M25 Other joint disorders, not elsewhere classified
0.888 0.112 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.887 0.113 0.000
I67.9 Cerebrovascular disease, unspecified
0.882 0.118 0.000
Chapter VII Diseases of the eye and adnexa
0.881 0.119 0.000
M18 Arthrosis of first carpometacarpal joint
0.878 0.122 0.000
M24 Other specific joint derangements
0.877 0.123 0.000
R63 Symptoms and signs concerning food and fluid intake
0.876 0.124 0.000
M80-M85 Disorders of bone density and structure
0.876 0.124 0.000
I61 Intracerebral haemorrhage
0.874 0.126 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.871 0.129 0.000
Chapter II Neoplasms
0.871 0.129 0.000
R00.1 Bradycardia, unspecified
0.871 0.129 0.000
M13.9 Arthritis, unspecified
0.867 0.133 0.000
G40.9 Epilepsy, unspecified
0.865 0.135 0.000
M07 Psoriatic and enteropathic arthropathies
0.865 0.135 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.860 0.140 0.000
R52 Pain, not elsewhere classified
0.858 0.142 0.000
W00-W19 Falls
0.858 0.142 0.000
I78 Diseases of capillaries
0.857 0.143 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.857 0.143 0.000
H65-H75 Diseases of middle ear and mastoid
0.856 0.144 0.000
R56 Convulsions, not elsewhere classified
0.856 0.144 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.855 0.145 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.854 0.146 0.000
I24 Other acute ischaemic heart diseases
0.854 0.146 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.854 0.146 0.000
I67.8 Other specified cerebrovascular diseases
0.853 0.147 0.000
L30 Other dermatitis
0.850 0.150 0.000
A30-A49 Other bacterial diseases
0.850 0.150 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.850 0.150 0.000
L40 Psoriasis
0.848 0.152 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.847 0.153 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.846 0.154 0.000
R09.0 Asphyxia
0.843 0.157 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.842 0.158 0.000
Z90.5 Acquired absence of kidney
0.837 0.163 0.000
Y45.1 Salicylates
0.836 0.164 0.000
Z98 Other postsurgical states
0.836 0.164 0.000
I25.3 Aneurysm of heart
0.834 0.166 0.000
M06 Other rheumatoid arthritis
0.833 0.167 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.833 0.167 0.000
R61 Hyperhidrosis
0.831 0.169 0.000
Z80 Family history of malignant neoplasm
0.830 0.170 0.000
Z04 Examination and observation for other reasons
0.828 0.172 0.000
O80-O84 Delivery
0.827 0.172 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.827 0.173 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.826 0.173 0.000
I21.9 Acute myocardial infarction, unspecified
0.825 0.175 0.000
M75.1 Rotator cuff syndrome
0.823 0.177 0.000
Y43.0 Antiallergic and antiemetic drugs
0.823 0.177 0.000
M75.4 Impingement syndrome of shoulder
0.821 0.179 0.000
R06.5 Mouth breathing
0.821 0.179 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.821 0.179 0.000
I20.9 Angina pectoris, unspecified
0.820 0.180 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.819 0.181 0.000
O60-O75 Complications of labour and delivery
0.818 0.182 0.000
R41.0 Disorientation, unspecified
0.815 0.185 0.000
M35 Other systemic involvement of connective tissue
0.815 0.185 0.000
R09.1 Pleurisy
0.815 0.185 0.000
Z94 Transplanted organ and tissue status
0.813 0.187 0.000
I78.1 Naevus, nonneoplastic
0.811 0.189 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.811 0.189 0.000
B37 Candidiasis
0.810 0.190 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.810 0.190 0.000
Z95.3 Presence of xenogenic heart valve
0.810 0.190 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.807 0.193 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.807 0.193 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.806 0.194 0.000
O43 Placental disorders
0.806 0.194 0.000
Z04.8 Examination and observation for other specified reasons
0.805 0.195 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.805 0.195 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.803 0.197 0.000
Y43.1 Antineoplastic antimetabolites
0.801 0.199 0.000
L29.8 Other pruritus
0.799 0.201 0.000
Z95.4 Presence of other heart-valve replacement
0.799 0.201 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.797 0.203 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.797 0.203 0.000
M23.8 Other internal derangements of knee
0.796 0.204 0.000
Z95.0 Presence of cardiac pacemaker
0.796 0.204 0.000
A00-A09 Intestinal infectious diseases
0.796 0.204 0.000
G30-G32 Other degenerative diseases of the nervous system
0.793 0.206 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.792 0.208 0.000
I25.5 Ischaemic cardiomyopathy
0.792 0.208 0.000
O40 Polyhydramnios
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.788 0.212 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.787 0.213 0.000
I69 Sequelae of cerebrovascular disease
0.783 0.217 0.000
I62 Other nontraumatic intracranial haemorrhage
0.782 0.218 0.000
R21 Rash and other nonspecific skin eruption
0.781 0.219 0.000
M07.3 Other psoriatic arthropathies
0.781 0.219 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.779 0.221 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.778 0.222 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.777 0.223 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.776 0.224 0.000
Z90.8 Acquired absence of other organs
0.776 0.224 0.000
R56.8 Other and unspecified convulsions
0.775 0.225 0.000
R05 Cough
0.775 0.225 0.000
L27 Dermatitis due to substances taken internally
0.775 0.225 0.000
O47.9 False labour, unspecified
0.775 0.225 0.000
R06.0 Dyspnoea
0.774 0.226 0.000
B25-B34 Other viral diseases
0.773 0.227 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.772 0.228 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.772 0.228 0.000
R20 Disturbances of skin sensation
0.772 0.228 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.770 0.230 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.770 0.230 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.769 0.231 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.769 0.231 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.768 0.232 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
Z93 Artificial opening status
0.767 0.233 0.000
M25.5 Pain in joint
0.766 0.234 0.000
L40.5 Arthropathic psoriasis
0.765 0.235 0.000
B95-B98 Bacterial, viral and other infectious agents
0.765 0.235 0.000
H55-H59 Other disorders of eye and adnexa
0.764 0.236 0.000
I65.2 Occlusion and stenosis of carotid artery
0.763 0.237 0.000
I22 Subsequent myocardial infarction
0.762 0.238 0.000
M45-M49 Spondylopathies
0.762 0.238 0.000
C50-C50 Malignant neoplasm of breast
0.762 0.238 0.000
M81 Osteoporosis without pathological fracture
0.759 0.241 0.000
R45 Symptoms and signs involving emotional state
0.759 0.241 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.757 0.243 0.000
O82 Single delivery by Caesarean section
0.754 0.246 0.000
R68 Other general symptoms and signs
0.753 0.247 0.000
M31 Other necrotising vasculopathies
0.752 0.248 0.000
M00-M03 Infectious arthropathies
0.751 0.249 0.000
Z90.7 Acquired absence of genital organ(s)
0.751 0.249 0.000
R52.1 Chronic intractable pain
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.748 0.252 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.748 0.252 0.000
Z84 Family history of other conditions
0.748 0.252 0.000
O48 Prolonged pregnancy
0.748 0.252 0.000
Z90.2 Acquired absence of lung [part of]
0.746 0.254 0.000
L50-L54 Urticaria and erythema
0.745 0.254 0.000
B02 Zoster [herpes zoster]
0.745 0.255 0.000
L40.0 Psoriasis vulgaris
0.745 0.255 0.000
C79 Secondary malignant neoplasm of other sites
0.745 0.255 0.000
V10-V19 Pedal cyclist injured in transport accident
0.744 0.256 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.744 0.256 0.000
M05 Seropositive rheumatoid arthritis
0.741 0.259 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.741 0.259 0.000
Z29 Need for other prophylactic measures
0.741 0.259 0.000
R40 Somnolence, stupor and coma
0.741 0.259 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.741 0.259 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.740 0.260 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.739 0.261 0.000
L30.9 Dermatitis, unspecified
0.738 0.262 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.738 0.262 0.000
H60-H62 Diseases of external ear
0.737 0.263 0.000
R01 Cardiac murmurs and other cardiac sounds
0.735 0.265 0.000
C15-C26 Malignant neoplasms of digestive organs
0.734 0.266 0.000
R61.9 Hyperhidrosis, unspecified
0.733 0.267 0.000
R63.0 Anorexia
0.733 0.267 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.732 0.268 0.000
Y57 Other and unspecified drugs and medicaments
0.731 0.269 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.730 0.270 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.730 0.270 0.000
B35 Dermatophytosis
0.729 0.271 0.000
W19 Unspecified fall
0.729 0.271 0.000
M10 Gout
0.728 0.272 0.000
H90-H95 Other disorders of ear
0.728 0.272 0.000
Y43.4 Immunosuppressive agents
0.727 0.273 0.000
M21 Other acquired deformities of limbs
0.726 0.274 0.000
R09.2 Respiratory arrest
0.724 0.276 0.000
O63 Long labour
0.724 0.276 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.723 0.277 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.722 0.278 0.000
A80-A89 Viral infections of the central nervous system
0.722 0.278 0.000
Z97.4 Presence of external hearing-aid
0.722 0.278 0.000
H10-H13 Disorders of conjunctiva
0.722 0.278 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.722 0.278 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
Y45.2 Propionic acid derivatives
0.721 0.279 0.000
M91-M94 Chondropathies
0.720 0.280 0.000
X60-X84 Intentional self-harm
0.720 0.280 0.000
M22 Disorders of patella
0.719 0.281 0.000
W20-W49 Exposure to inanimate mechanical forces
0.718 0.281 0.000
R52.0 Acute pain
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
H66 Suppurative and unspecified otitis media
0.717 0.283 0.000
M24.1 Other articular cartilage disorders
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
A41 Other septicaemia
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
I72 Other aneurysm
0.715 0.285 0.000
M86-M90 Other osteopathies
0.714 0.285 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.714 0.286 0.000
G44 Other headache syndromes
0.713 0.287 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
O72 Postpartum haemorrhage
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
H73 Other disorders of tympanic membrane
0.711 0.289 0.000
C34 Malignant neoplasm of bronchus and lung
0.711 0.289 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.289 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.289 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.711 0.289 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.289 0.000
H74 Other disorders of middle ear and mastoid
0.710 0.290 0.000
R46 Symptoms and signs involving appearance and behaviour
0.710 0.290 0.000
R43 Disturbances of smell and taste
0.710 0.290 0.000
M25.8 Other specified joint disorders
0.710 0.290 0.000
O45 Premature separation of placenta [abruptio placentae]
0.710 0.290 0.000
O44 Placenta praevia
0.710 0.290 0.000
O41 Other disorders of amniotic fluid and membranes
0.710 0.290 0.000
O33 Maternal care for known or suspected disproportion
0.710 0.290 0.000
O31 Complications specific to multiple gestation
0.710 0.290 0.000
O46.9 Antepartum haemorrhage, unspecified
0.710 0.290 0.000
L29.9 Pruritus, unspecified
0.709 0.291 0.000
Z98.1 Arthrodesis status
0.709 0.291 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.709 0.291 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.709 0.291 0.000
M77 Other enthesopathies
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
O82.0 Delivery by elective Caesarean section
0.708 0.292 0.000
M75.9 Shoulder lesion, unspecified
0.708 0.292 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.708 0.292 0.000
I67.2 Cerebral atherosclerosis
0.706 0.293 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.705 0.295 0.000
I24.8 Other forms of acute ischaemic heart disease
0.705 0.295 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.705 0.295 0.000
Y45.0 Opioids and related analgesics
0.704 0.296 0.000
M14 Arthropathies in other diseases classified elsewhere
0.704 0.296 0.000
M12 Other specific arthropathies
0.704 0.296 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.703 0.297 0.000
I70 Atherosclerosis
0.703 0.297 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.703 0.297 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.297 0.000
R06.1 Stridor
0.702 0.298 0.000
G90-G99 Other disorders of the nervous system
0.702 0.298 0.000
M13.98 Arthritis, unspecified (Other)
0.702 0.298 0.000
M23.9 Internal derangement of knee, unspecified
0.702 0.298 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.702 0.298 0.000
M23.5 Chronic instability of knee
0.702 0.298 0.000
M23.1 Discoid meniscus (congenital)
0.702 0.298 0.000
M23.0 Cystic meniscus
0.702 0.298 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.702 0.298 0.000
Y40 Systemic antibiotics
0.701 0.298 0.000
M35.0 Sicca syndrome [Sjogren]
0.701 0.299 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.701 0.299 0.000
R04 Haemorrhage from respiratory passages
0.701 0.299 0.000
Z97.8 Presence of other specified devices
0.700 0.300 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.700 0.300 0.000
Z82.2 Family history of deafness and hearing loss
0.700 0.300 0.000
Z82.1 Family history of blindness and visual loss
0.700 0.300 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.700 0.300 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.700 0.300 0.000
Y43.9 Primarily systemic agent, unspecified
0.699 0.300 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.699 0.300 0.000
Y43.6 Enzymes, not elsewhere classified
0.699 0.300 0.000
Y43.5 Acidifying and alkalising agents
0.699 0.300 0.000
Y43.2 Antineoplastic natural products
0.699 0.300 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
L28 Lichen simplex chronicus and prurigo
0.698 0.301 0.000
L25 Unspecified contact dermatitis
0.698 0.301 0.000
L24 Irritant contact dermatitis
0.698 0.301 0.000
L23 Allergic contact dermatitis
0.698 0.301 0.000
L21 Seborrhoeic dermatitis
0.698 0.301 0.000
L20 Atopic dermatitis
0.698 0.301 0.000
L26 Exfoliative dermatitis
0.698 0.301 0.000
L22 Diaper [napkin] dermatitis
0.698 0.301 0.000
I60 Subarachnoid haemorrhage
0.697 0.303 0.000
Chapter V Mental and behavioural disorders
0.697 0.303 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.696 0.303 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.696 0.304 0.000
I21.4 Acute subendocardial myocardial infarction
0.696 0.304 0.000
O42 Premature rupture of membranes
0.696 0.304 0.000
M34 Systemic sclerosis
0.695 0.305 0.000
Z80.3 Family history of malignant neoplasm of breast
0.694 0.306 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.694 0.306 0.000
R62 Lack of expected normal physiological development
0.694 0.306 0.000
R64 Cachexia
0.694 0.306 0.000
R58 Haemorrhage, not elsewhere classified
0.694 0.306 0.000
C77.3 Axillary and upper limb lymph nodes
0.694 0.306 0.000
Z89 Acquired absence of limb
0.693 0.307 0.000
M06.9 Rheumatoid arthritis, unspecified
0.692 0.307 0.000
I20.1 Angina pectoris with documented spasm
0.692 0.308 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.692 0.308 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.692 0.308 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.692 0.308 0.000
Z96 Presence of other functional implants
0.691 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.691 0.309 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.691 0.309 0.000
M50-M54 Other dorsopathies
0.691 0.309 0.000
L57.0 Actinic keratosis
0.691 0.309 0.000
M23.4 Loose body in knee
0.691 0.309 0.000
M23.37 Other meniscus derangements-Capsular lig
0.691 0.309 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.691 0.309 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.691 0.309 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.691 0.309 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.691 0.309 0.000
L60-L75 Disorders of skin appendages
0.689 0.311 0.000
G30 Alzheimer's disease
0.689 0.311 0.000
B44 Aspergillosis
0.689 0.311 0.000
M19 Other arthrosis
0.688 0.312 0.000
M11 Other crystal arthropathies
0.686 0.314 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.685 0.315 0.000
R41.2 Retrograde amnesia
0.685 0.315 0.000
R41.1 Anterograde amnesia
0.685 0.315 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.685 0.315 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.684 0.316 0.000
H02 Other disorders of eyelid
0.684 0.316 0.000
C50 Malignant neoplasm of breast
0.684 0.316 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.683 0.317 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.683 0.317 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.682 0.317 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.682 0.317 0.000
I67.5 Moyamoya disease
0.682 0.317 0.000
I67.4 Hypertensive encephalopathy
0.682 0.317 0.000
I67.3 Progressive vascular leukoencephalopathy
0.682 0.317 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.682 0.317 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.682 0.318 0.000
R09.3 Abnormal sputum
0.682 0.318 0.000
L29.3 Anogenital pruritus, unspecified
0.681 0.319 0.000
L29.2 Pruritus vulvae
0.681 0.319 0.000
L29.1 Pruritus scroti
0.681 0.319 0.000
O62 Abnormalities of forces of labour
0.681 0.319 0.000
R26 Abnormalities of gait and mobility
0.680 0.320 0.000
M75.3 Calcific tendinitis of shoulder
0.679 0.321 0.000
W06 Fall involving bed
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.678 0.322 0.000
Z98.8 Other specified postsurgical states
0.678 0.322 0.000
B37.3 Candidiasis of vulva and vagina
0.677 0.322 0.000
Y52 Agents primarily affecting the cardiovascular system
0.677 0.323 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.677 0.323 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.676 0.324 0.000
G41 Status epilepticus
0.676 0.324 0.000
M75.0 Adhesive capsulitis of shoulder
0.676 0.324 0.000
O00-O08 Pregnancy with abortive outcome
0.676 0.324 0.000
H52 Disorders of refraction and accommodation
0.675 0.325 0.000
M81.9 Osteoporosis, unspecified
0.675 0.325 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.675 0.325 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.674 0.325 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.673 0.327 0.000
H69 Other disorders of Eustachian tube
0.672 0.327 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.672 0.328 0.000
R53 Malaise and fatigue
0.672 0.328 0.000
B15-B19 Viral hepatitis
0.671 0.329 0.000
M76 Enthesopathies of lower limb, excluding foot
0.671 0.329 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.671 0.329 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.671 0.329 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.671 0.329 0.000
R73 Elevated blood glucose level
0.669 0.331 0.000
I73 Other peripheral vascular diseases
0.669 0.331 0.000
O47.0 False labour before 37 completed weeks of gestation
0.669 0.331 0.000
H65 Nonsuppurative otitis media
0.668 0.332 0.000
Z94.8 Other transplanted organ and tissue status
0.667 0.333 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.667 0.333 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.667 0.333 0.000
Y86 Sequelae of other accidents
0.667 0.333 0.000
O30 Multiple gestation
0.666 0.334 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.666 0.334 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.665 0.335 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.665 0.335 0.000
O43.1 Malformation of placenta
0.664 0.335 0.000
C80 Malignant neoplasm without specification of site
0.664 0.336 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.663 0.337 0.000
R00.0 Tachycardia, unspecified
0.663 0.337 0.000
O63.1 Prolonged second stage (of labour)
0.662 0.338 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.662 0.338 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.662 0.338 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.662 0.338 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.662 0.338 0.000
B02.9 Zoster without complication
0.661 0.338 0.000
R57 Shock, not elsewhere classified
0.661 0.339 0.000
I05-I09 Chronic rheumatic heart diseases
0.661 0.339 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.660 0.339 0.000
I77 Other disorders of arteries and arterioles
0.660 0.340 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.660 0.340 0.000
L30.8 Other specified dermatitis
0.660 0.340 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.659 0.340 0.000
Y45.8 Other analgesics and antipyretics
0.659 0.340 0.000
Y45.5 4-Aminophenol derivatives
0.659 0.340 0.000
Y45.4 Antirheumatics
0.659 0.340 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.659 0.341 0.000
A04 Other bacterial intestinal infections
0.658 0.341 0.000
Z83 Family history of other specific disorders
0.658 0.342 0.000
O72.1 Other immediate postpartum haemorrhage
0.658 0.342 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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