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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112833835
log Bayes Factor = 14.7107
Chromosome 1   position 225,084,059  (GRCh37) Explore rs112833835 on Ensembl!
Variant rs112833835 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I50 Heart failure
0.995 0.005 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
S60-S69 Injuries to the wrist and hand
0.992 0.008 0.000
I50.0 Congestive heart failure
0.981 0.019 0.000
Chapter I Certain infectious and parasitic diseases
0.979 0.021 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.970 0.030 0.000
J44 Other chronic obstructive pulmonary disease
0.968 0.032 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.956 0.044 0.000
Chapter VIII Diseases of the ear and mastoid process
0.952 0.048 0.000
S61 Open wound of wrist and hand
0.951 0.049 0.000
J45 Asthma
0.951 0.049 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.941 0.059 0.000
M15-M19 Arthrosis
0.941 0.059 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.940 0.060 0.000
I44 Atrioventricular and left bundle-branch block
0.937 0.063 0.000
Z85 Personal history of malignant neoplasm
0.929 0.071 0.000
I51 Complications and ill-defined descriptions of heart disease
0.928 0.072 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.925 0.075 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.924 0.076 0.000
Z88.0 Personal history of allergy to penicillin
0.921 0.079 0.000
S61.0 Open wound of finger(s) without damage to nail
0.920 0.080 0.000
B95-B98 Bacterial, viral and other infectious agents
0.919 0.080 0.000
J45.9 Asthma, unspecified
0.917 0.083 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.916 0.084 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.915 0.085 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.915 0.085 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.914 0.086 0.000
M19 Other arthrosis
0.914 0.086 0.000
M65-M68 Disorders of synovium and tendon
0.912 0.088 0.000
O60-O75 Complications of labour and delivery
0.907 0.093 0.000
J95-J99 Other diseases of the respiratory system
0.906 0.094 0.000
M50-M54 Other dorsopathies
0.905 0.095 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.904 0.096 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.903 0.097 0.000
S80-S89 Injuries to the knee and lower leg
0.901 0.099 0.000
I34 Nonrheumatic mitral valve disorders
0.901 0.099 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.899 0.101 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.899 0.101 0.000
A00-A09 Intestinal infectious diseases
0.896 0.104 0.000
M19.9 Arthrosis, unspecified
0.894 0.106 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.886 0.114 0.000
J30-J39 Other diseases of upper respiratory tract
0.885 0.115 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.885 0.115 0.000
I51.7 Cardiomegaly
0.884 0.116 0.000
Chapter II Neoplasms
0.884 0.116 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.880 0.120 0.000
I05-I09 Chronic rheumatic heart diseases
0.878 0.122 0.000
J90-J94 Other diseases of pleura
0.875 0.125 0.000
Z87 Personal history of other diseases and conditions
0.874 0.126 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.872 0.128 0.000
I46 Cardiac arrest
0.868 0.132 0.000
I50.1 Left ventricular failure
0.862 0.138 0.000
I83 Varicose veins of lower extremities
0.860 0.140 0.000
Z53.9 Procedure not carried out, unspecified reason
0.856 0.144 0.000
S62 Fracture at wrist and hand level
0.852 0.148 0.000
H60-H62 Diseases of external ear
0.851 0.149 0.000
Z93 Artificial opening status
0.847 0.153 0.000
Chapter XIV Diseases of the genitourinary system
0.845 0.155 0.000
I50.9 Heart failure, unspecified
0.842 0.158 0.000
E70-E90 Metabolic disorders
0.842 0.158 0.000
J42 Unspecified chronic bronchitis
0.841 0.158 0.000
I80 Phlebitis and thrombophlebitis
0.840 0.160 0.000
J98 Other respiratory disorders
0.839 0.161 0.000
A04 Other bacterial intestinal infections
0.836 0.164 0.000
S40-S49 Injuries to the shoulder and upper arm
0.834 0.166 0.000
S00-S09 Injuries to the head
0.833 0.167 0.000
C50-C50 Malignant neoplasm of breast
0.831 0.169 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.831 0.169 0.000
B35-B49 Mycoses
0.827 0.173 0.000
H65-H75 Diseases of middle ear and mastoid
0.827 0.173 0.000
Z99.3 Dependence on wheelchair
0.826 0.174 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.826 0.174 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.825 0.175 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.824 0.176 0.000
B15-B19 Viral hepatitis
0.822 0.178 0.000
M70-M79 Other soft tissue disorders
0.820 0.180 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.818 0.181 0.000
O70 Perineal laceration during delivery
0.816 0.184 0.000
I20-I25 Ischaemic heart diseases
0.814 0.186 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.814 0.186 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.813 0.187 0.000
I42 Cardiomyopathy
0.811 0.188 0.000
H80-H83 Diseases of inner ear
0.811 0.189 0.000
Z98 Other postsurgical states
0.808 0.192 0.000
Z94 Transplanted organ and tissue status
0.808 0.192 0.000
J09-J18 Influenza and pneumonia
0.805 0.195 0.000
M65 Synovitis and tenosynovitis
0.802 0.198 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.802 0.198 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.798 0.202 0.000
N17-N19 Renal failure
0.797 0.203 0.000
J32 Chronic sinusitis
0.796 0.204 0.000
M50 Cervical disk disorders
0.795 0.205 0.000
C50 Malignant neoplasm of breast
0.794 0.206 0.000
M54 Dorsalgia
0.794 0.206 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.791 0.209 0.000
Chapter XX External causes of morbidity and mortality
0.791 0.209 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.790 0.210 0.000
N20-N23 Urolithiasis
0.790 0.210 0.000
I44.0 Atrioventricular block, first degree
0.790 0.210 0.000
M05-M14 Inflammatory polyarthropathies
0.789 0.211 0.000
I44.1 Atrioventricular block, second degree
0.788 0.212 0.000
I46.0 Cardiac arrest with successful resuscitation
0.788 0.212 0.000
J98.1 Pulmonary collapse
0.783 0.217 0.000
I08 Multiple valve diseases
0.782 0.218 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.777 0.223 0.000
Z90.2 Acquired absence of lung [part of]
0.776 0.224 0.000
I34.0 Mitral (valve) insufficiency
0.776 0.224 0.000
Z95.0 Presence of cardiac pacemaker
0.776 0.224 0.000
I44.3 Other and unspecified atrioventricular block
0.775 0.225 0.000
M67 Other disorders of synovium and tendon
0.775 0.225 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.774 0.226 0.000
I10-I15 Hypertensive diseases
0.774 0.226 0.000
O46.9 Antepartum haemorrhage, unspecified
0.773 0.227 0.000
I35 Nonrheumatic aortic valve disorders
0.772 0.228 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.771 0.229 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.769 0.231 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.768 0.232 0.000
I82 Other venous embolism and thrombosis
0.768 0.232 0.000
N18 Chronic renal failure
0.768 0.232 0.000
M18 Arthrosis of first carpometacarpal joint
0.767 0.233 0.000
Z90.1 Acquired absence of breast(s)
0.766 0.234 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.765 0.235 0.000
S60 Superficial injury of wrist and hand
0.765 0.235 0.000
I47 Paroxysmal tachycardia
0.765 0.235 0.000
A04.5 Campylobacter enteritis
0.764 0.236 0.000
M45-M49 Spondylopathies
0.763 0.237 0.000
O47 False labour
0.762 0.238 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.762 0.238 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.761 0.239 0.000
C50.4 Upper-outer quadrant of breast
0.761 0.239 0.000
O72 Postpartum haemorrhage
0.759 0.241 0.000
J47 Bronchiectasis
0.758 0.242 0.000
Z42 Follow-up care involving plastic surgery
0.758 0.242 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.756 0.244 0.000
I34.1 Mitral (valve) prolapse
0.755 0.245 0.000
Z88.6 Personal history of allergy to analgesic agent
0.754 0.246 0.000
S50-S59 Injuries to the elbow and forearm
0.754 0.246 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.754 0.246 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.754 0.246 0.000
S82 Fracture of lower leg, including ankle
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.753 0.247 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.752 0.248 0.000
J84 Other interstitial pulmonary diseases
0.750 0.250 0.000
Z97 Presence of other devices
0.750 0.250 0.000
M16 Coxarthrosis [arthrosis of hip]
0.748 0.252 0.000
E87.6 Hypokalaemia
0.746 0.254 0.000
Z49 Care involving dialysis
0.746 0.254 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.745 0.255 0.000
T79-T79 Certain early complications of trauma
0.745 0.255 0.000
A08 Viral and other specified intestinal infections
0.743 0.257 0.000
S70-S79 Injuries to the hip and thigh
0.743 0.257 0.000
N18.9 Chronic renal failure, unspecified
0.743 0.257 0.000
O70.0 First degree perineal laceration during delivery
0.743 0.257 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.741 0.259 0.000
M91-M94 Chondropathies
0.741 0.259 0.000
N20 Calculus of kidney and ureter
0.741 0.259 0.000
H61 Other disorders of external ear
0.740 0.260 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.739 0.261 0.000
Z37 Outcome of delivery
0.737 0.263 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.737 0.263 0.000
I33 Acute and subacute endocarditis
0.735 0.265 0.000
M79.6 Pain in limb
0.734 0.266 0.000
J00-J06 Acute upper respiratory infections
0.733 0.267 0.000
J81 Pulmonary oedema
0.733 0.267 0.000
N60-N64 Disorders of breast
0.731 0.269 0.000
Z85.6 Personal history of leukaemia
0.730 0.270 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.729 0.271 0.000
I87 Other disorders of veins
0.728 0.272 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
S81 Open wound of lower leg
0.723 0.276 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.721 0.279 0.000
S61.8 Open wound of other parts of wrist and hand
0.721 0.279 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.720 0.280 0.000
E83 Disorders of mineral metabolism
0.720 0.280 0.000
C51-C58 Malignant neoplasms of female genital organs
0.720 0.280 0.000
Z99.8 Dependence on other enabling machines and devices
0.720 0.280 0.000
S42 Fracture of shoulder and upper arm
0.719 0.281 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.719 0.281 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.719 0.281 0.000
B37 Candidiasis
0.718 0.282 0.000
J35 Chronic diseases of tonsils and adenoids
0.718 0.282 0.000
Z30 Contraceptive management
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I25 Chronic ischaemic heart disease
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.715 0.285 0.000
O44 Placenta praevia
0.714 0.286 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.287 0.000
J46 Status asthmaticus
0.713 0.287 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.713 0.287 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.288 0.000
S20-S29 Injuries to the thorax
0.711 0.289 0.000
M65.3 Trigger finger
0.711 0.289 0.000
T66-T78 Other and unspecified effects of external causes
0.711 0.289 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.711 0.289 0.000
S69 Other and unspecified injuries of wrist and hand
0.711 0.289 0.000
S67 Crushing injury of wrist and hand
0.711 0.289 0.000
S65 Injury of blood vessels at wrist and hand level
0.711 0.289 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.711 0.289 0.000
Z46 Fitting and adjustment of other devices
0.710 0.289 0.000
Z34 Supervision of normal pregnancy
0.710 0.290 0.000
Z48 Other surgical follow-up care
0.710 0.290 0.000
J33 Nasal polyp
0.709 0.290 0.000
B18 Chronic viral hepatitis
0.709 0.291 0.000
Chapter XXII Codes for special purposes
0.708 0.292 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.708 0.292 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.707 0.293 0.000
E20-E35 Disorders of other endocrine glands
0.706 0.293 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.706 0.294 0.000
I44.7 Left bundle-branch block, unspecified
0.706 0.294 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.705 0.295 0.000
J32.9 Chronic sinusitis, unspecified
0.705 0.295 0.000
O80-O84 Delivery
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.702 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
B65-B83 Helminthiases
0.702 0.298 0.000
B50-B64 Protozoal diseases
0.702 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
H81 Disorders of vestibular function
0.702 0.298 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.702 0.298 0.000
I24 Other acute ischaemic heart diseases
0.702 0.298 0.000
Z98.0 Intestinal bypass and anastomosis status
0.700 0.300 0.000
M50.2 Other cervical disk displacement
0.700 0.300 0.000
Z93.0 Tracheostomy status
0.700 0.300 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.699 0.300 0.000
S68 Traumatic amputation of wrist and hand
0.697 0.303 0.000
M40-M43 Deforming dorsopathies
0.697 0.303 0.000
J45.0 Predominantly allergic asthma
0.696 0.303 0.000
Z95.3 Presence of xenogenic heart valve
0.696 0.304 0.000
M79.66 Pain in limb (Lower leg)
0.696 0.304 0.000
J93 Pneumothorax
0.696 0.304 0.000
Z93.1 Gastrostomy status
0.696 0.304 0.000
S01 Open wound of head
0.696 0.304 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.696 0.304 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.696 0.304 0.000
H60 Otitis externa
0.695 0.305 0.000
I49 Other cardiac arrhythmias
0.695 0.305 0.000
J90 Pleural effusion, not elsewhere classified
0.694 0.306 0.000
C64-C68 Malignant neoplasms of urinary tract
0.694 0.306 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.694 0.306 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.692 0.308 0.000
Z95.4 Presence of other heart-valve replacement
0.692 0.308 0.000
Z90.7 Acquired absence of genital organ(s)
0.692 0.308 0.000
I85 Oesophageal varices
0.691 0.309 0.000
J60-J70 Lung diseases due to external agents
0.691 0.309 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.691 0.309 0.000
Z35 Supervision of high-risk pregnancy
0.690 0.310 0.000
O42 Premature rupture of membranes
0.689 0.311 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.688 0.312 0.000
Z53.0 Procedure not carried out because of contraindication
0.688 0.312 0.000
M80-M85 Disorders of bone density and structure
0.687 0.313 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.686 0.314 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.686 0.314 0.000
O85-O92 Complications predominantly related to the puerperium
0.685 0.314 0.000
Z63 Other problems related to primary support group, including family circumstances
0.685 0.314 0.000
A04.8 Other specified bacterial intestinal infections
0.685 0.315 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.685 0.315 0.000
S64 Injury of nerves at wrist and hand level
0.685 0.315 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.684 0.316 0.000
S61.7 Multiple open wounds of wrist and hand
0.682 0.318 0.000
Z36 Antenatal screening
0.682 0.318 0.000
N20.1 Calculus of ureter
0.682 0.318 0.000
L20-L30 Dermatitis and eczema
0.682 0.318 0.000
J45.8 Mixed asthma
0.681 0.318 0.000
J45.1 Nonallergic asthma
0.681 0.318 0.000
Z99.2 Dependence on renal dialysis
0.680 0.320 0.000
I86 Varicose veins of other sites
0.680 0.320 0.000
E87.7 Fluid overload
0.678 0.322 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.678 0.322 0.000
Z47 Other orthopaedic follow-up care
0.678 0.322 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.678 0.322 0.000
M67.8 Other specified disorders of synovium and tendon
0.677 0.323 0.000
E00-E07 Disorders of thyroid gland
0.677 0.323 0.000
Z80 Family history of malignant neoplasm
0.675 0.325 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.675 0.325 0.000
I88 Nonspecific lymphadenitis
0.674 0.325 0.000
I81 Portal vein thrombosis
0.674 0.325 0.000
M15 Polyarthrosis
0.674 0.326 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.674 0.326 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.673 0.327 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.673 0.327 0.000
I44.6 Other and unspecified fascicular block
0.672 0.328 0.000
I44.5 Left posterior fascicular block
0.672 0.328 0.000
I44.4 Left anterior fascicular block
0.672 0.328 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.671 0.329 0.000
J94 Other pleural conditions
0.670 0.330 0.000
H66 Suppurative and unspecified otitis media
0.669 0.331 0.000
J92 Pleural plaque
0.669 0.331 0.000
I38 Endocarditis, valve unspecified
0.668 0.332 0.000
M19.0 Primary arthrosis of other joints
0.667 0.333 0.000
L50-L54 Urticaria and erythema
0.667 0.333 0.000
S80 Superficial injury of lower leg
0.666 0.334 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.666 0.334 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.666 0.334 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.666 0.334 0.000
I51.6 Cardiovascular disease, unspecified
0.665 0.335 0.000
I51.5 Myocardial degeneration
0.665 0.335 0.000
I51.4 Myocarditis, unspecified
0.665 0.335 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.665 0.335 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.665 0.335 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.665 0.335 0.000
I51.0 Cardiac septal defect, acquired
0.665 0.335 0.000
Z93.3 Colostomy status
0.665 0.335 0.000
O63 Long labour
0.663 0.337 0.000
Z54 Convalescence
0.663 0.337 0.000
Z52 Donors of organs and tissues
0.663 0.337 0.000
Z44 Fitting and adjustment of external prosthetic device
0.663 0.337 0.000
I44.2 Atrioventricular block, complete
0.663 0.337 0.000
E40-E46 Malnutrition
0.663 0.337 0.000
Z95.2 Presence of prosthetic heart valve
0.662 0.338 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.662 0.338 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.661 0.339 0.000
Z87.0 Personal history of diseases of the respiratory system
0.661 0.339 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.660 0.339 0.000
N23 Unspecified renal colic
0.660 0.339 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.660 0.340 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.659 0.341 0.000
E55 Vitamin D deficiency
0.659 0.341 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.659 0.341 0.000
Z29 Need for other prophylactic measures
0.658 0.342 0.000
Z90.8 Acquired absence of other organs
0.657 0.343 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.656 0.344 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.656 0.344 0.000
Z99.4 Dependence on artificial heart
0.656 0.344 0.000
Z99.1 Dependence on respirator
0.656 0.344 0.000
Z99.0 Dependence on aspirator
0.656 0.344 0.000
J31.0 Chronic rhinitis
0.656 0.344 0.000
Z90.0 Acquired absence of part of head and neck
0.655 0.345 0.000
M19.8 Other specified arthrosis
0.655 0.345 0.000
M19.2 Other secondary arthrosis
0.655 0.345 0.000
M19.1 Posttraumatic arthrosis of other joints
0.655 0.345 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.655 0.345 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.654 0.346 0.000
M66 Spontaneous rupture of synovium and tendon
0.654 0.346 0.000
M79.8 Other specified soft tissue disorders
0.654 0.346 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.653 0.347 0.000
I07 Rheumatic tricuspid valve diseases
0.652 0.348 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.652 0.348 0.000
Z95.1 Presence of aortocoronary bypass graft
0.651 0.349 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.651 0.349 0.000
C50.3 Lower-inner quadrant of breast
0.651 0.349 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.651 0.349 0.000
J32.2 Chronic ethmoidal sinusitis
0.650 0.349 0.000
L40-L45 Papulosquamous disorders
0.650 0.350 0.000
O74 Complications of anaesthesia during labour and delivery
0.650 0.350 0.000
O73 Retained placenta and membranes, without haemorrhage
0.650 0.350 0.000
O71 Other obstetric trauma
0.650 0.350 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.650 0.350 0.000
O66 Other obstructed labour
0.650 0.350 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.650 0.350 0.000
O62 Abnormalities of forces of labour
0.650 0.350 0.000
O61 Failed induction of labour
0.650 0.350 0.000
O60 Preterm delivery
0.650 0.350 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.650 0.350 0.000
J96 Respiratory failure, not elsewhere classified
0.650 0.350 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.650 0.350 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.649 0.351 0.000
M53 Other dorsopathies, not elsewhere classified
0.649 0.351 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.648 0.352 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.648 0.352 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.648 0.352 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.648 0.352 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.648 0.352 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.648 0.352 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.648 0.352 0.000
Z22 Carrier of infectious disease
0.648 0.352 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.647 0.353 0.000
D00-D09 In situ neoplasms
0.647 0.353 0.000
I42.0 Dilated cardiomyopathy
0.647 0.353 0.000
M65.34 Trigger finger-Hand
0.647 0.353 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.646 0.354 0.000
Z91.6 Personal history of other physical trauma
0.646 0.354 0.000
Z94.0 Kidney transplant status
0.646 0.354 0.000
S62.6 Fracture of other finger
0.646 0.354 0.000
S89 Other and unspecified injuries of lower leg
0.646 0.354 0.000
S88 Traumatic amputation of lower leg
0.646 0.354 0.000
S87 Crushing injury of lower leg
0.646 0.354 0.000
S86 Injury of muscle and tendon at lower leg level
0.646 0.354 0.000
S85 Injury of blood vessels at lower leg level
0.646 0.354 0.000
S84 Injury of nerves at lower leg level
0.646 0.354 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.646 0.354 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.646 0.354 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.646 0.354 0.000
I51.9 Heart disease, unspecified
0.645 0.354 0.000
S06 Intracranial injury
0.645 0.355 0.000
I82.8 Embolism and thrombosis of other specified veins
0.645 0.355 0.000
J43 Emphysema
0.645 0.355 0.000
W00-W19 Falls
0.645 0.355 0.000
O45 Premature separation of placenta [abruptio placentae]
0.645 0.355 0.000
O43 Placental disorders
0.645 0.355 0.000
O41 Other disorders of amniotic fluid and membranes
0.645 0.355 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.645 0.355 0.000
O33 Maternal care for known or suspected disproportion
0.645 0.355 0.000
O31 Complications specific to multiple gestation
0.645 0.355 0.000
O30 Multiple gestation
0.645 0.355 0.000
O40 Polyhydramnios
0.645 0.355 0.000
Z39 Postpartum care and examination
0.644 0.355 0.000
Z38 Liveborn infants according to place of birth
0.644 0.355 0.000
Z32 Pregnancy examination and test
0.644 0.355 0.000
Z31 Procreative management
0.644 0.355 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.643 0.357 0.000
A07 Other protozoal intestinal diseases
0.642 0.357 0.000
A06 Amoebiasis
0.642 0.357 0.000
A05 Other bacterial foodborne intoxications
0.642 0.357 0.000
A03 Shigellosis
0.642 0.357 0.000
A02 Other Salmonella infections
0.642 0.357 0.000
A01 Typhoid and paratyphoid fevers
0.642 0.357 0.000
A00 Cholera
0.642 0.357 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.642 0.358 0.000
Z90.3 Acquired absence of part of stomach
0.641 0.359 0.000
M19.98 Arthrosis, unspecified (Other)
0.641 0.359 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.641 0.359 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.640 0.359 0.000
I08.0 Disorders of both mitral and aortic valves
0.640 0.360 0.000
H71 Cholesteatoma of middle ear
0.640 0.360 0.000
M13 Other arthritis
0.640 0.360 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.639 0.361 0.000
M16.0 Primary coxarthrosis, bilateral
0.639 0.361 0.000
O48 Prolonged pregnancy
0.638 0.362 0.000
E10-E14 Diabetes mellitus
0.638 0.362 0.000
Z43 Attention to artificial openings
0.638 0.362 0.000
I51.8 Other ill-defined heart diseases
0.637 0.363 0.000
M54.9 Dorsalgia, unspecified
0.636 0.364 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.636 0.364 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.635 0.365 0.000
M54.3 Sciatica
0.635 0.365 0.000
I35.8 Other aortic valve disorders
0.635 0.365 0.000
J37 Chronic laryngitis and laryngotracheitis
0.635 0.365 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.635 0.365 0.000
J80 Adult respiratory distress syndrome
0.635 0.365 0.000
J98.4 Other disorders of lung
0.635 0.365 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.634 0.366 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.634 0.366 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.634 0.366 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.634 0.366 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.634 0.366 0.000
S62.3 Fracture of other metacarpal bone
0.633 0.367 0.000
H73 Other disorders of tympanic membrane
0.633 0.367 0.000
A08.4 Viral intestinal infection, unspecified
0.633 0.367 0.000
Z88.5 Personal history of allergy to narcotic agent
0.633 0.367 0.000
I31 Other diseases of pericardium
0.631 0.368 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.631 0.369 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.631 0.369 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.631 0.369 0.000
H72 Perforation of tympanic membrane
0.631 0.369 0.000
E65-E68 Obesity and other hyperalimentation
0.630 0.370 0.000
I09 Other rheumatic heart diseases
0.630 0.370 0.000
I06 Rheumatic aortic valve diseases
0.630 0.370 0.000
I05 Rheumatic mitral valve diseases
0.630 0.370 0.000
J18 Pneumonia, organism unspecified
0.629 0.371 0.000
H61.2 Impacted cerumen
0.629 0.371 0.000
I47.2 Ventricular tachycardia
0.628 0.372 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.628 0.372 0.000
I12 Hypertensive renal disease
0.628 0.372 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.628 0.372 0.000
J91 Pleural effusion in conditions classified elsewhere
0.627 0.373 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.627 0.373 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.627 0.373 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.626 0.373 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.626 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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