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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1129640
log Bayes Factor = 63.7178
Chromosome 6   position 31,506,624  (GRCh37) Explore rs1129640 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.006 0.994
E14.3 With ophthalmic complications
0.000 0.007 0.993
E14.9 Without complications
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.014 0.986
I22 Subsequent myocardial infarction
0.000 0.015 0.985
E10.4 With neurological complications
0.000 0.016 0.984
I25.5 Ischaemic cardiomyopathy
0.000 0.016 0.984
I21 Acute myocardial infarction
0.000 0.016 0.984
I20.9 Angina pectoris, unspecified
0.000 0.017 0.983
G35-G37 Demyelinating diseases of the central nervous system
0.982 0.018 0.000
G37 Other demyelinating diseases of central nervous system
0.979 0.021 0.000
I25.2 Old myocardial infarction
0.000 0.022 0.978
I20.0 Unstable angina
0.000 0.029 0.971
G37.9 Demyelinating disease of central nervous system, unspecified
0.970 0.030 0.000
E83.1 Disorders of iron metabolism
0.959 0.041 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.045 0.955
I21.9 Acute myocardial infarction, unspecified
0.000 0.067 0.933
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.077 0.923
R07.4 Chest pain, unspecified
0.000 0.089 0.911
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.101 0.899
E13 Other specified diabetes mellitus
0.000 0.105 0.895
I21.4 Acute subendocardial myocardial infarction
0.000 0.107 0.893
E10.2 With renal complications
0.000 0.121 0.879
E11.2 With renal complications
0.000 0.122 0.878
I24 Other acute ischaemic heart diseases
0.000 0.122 0.878
L40-L45 Papulosquamous disorders
0.000 0.127 0.873
G37.8 Other specified demyelinating diseases of central nervous system
0.860 0.140 0.000
E11.0 With coma
0.000 0.157 0.843
L40.8 Other psoriasis
0.000 0.160 0.840
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.161 0.839
I10 Essential (primary) hypertension
0.000 0.161 0.839
L43 Lichen planus
0.000 0.163 0.837
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.165 0.834
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.166 0.834
E11.1 With ketoacidosis
0.000 0.170 0.830
E70-E90 Metabolic disorders
0.001 0.173 0.826
E78.8 Other disorders of lipoprotein metabolism
0.000 0.174 0.826
E14.4 With neurological complications
0.000 0.177 0.823
E13.9 Without complications
0.000 0.180 0.820
E10.8 With unspecified complications
0.000 0.183 0.817
E10.5 With peripheral circulatory complications
0.000 0.185 0.815
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.201 0.799
L43.9 Lichen planus, unspecified
0.000 0.204 0.796
E10.0 With coma
0.000 0.209 0.791
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.791 0.209 0.000
I25.3 Aneurysm of heart
0.000 0.212 0.788
I23 Certain current complications following acute myocardial infarction
0.000 0.226 0.774
I24.8 Other forms of acute ischaemic heart disease
0.000 0.237 0.763
E78.2 Mixed hyperlipidaemia
0.000 0.238 0.762
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.239 0.761
L40.0 Psoriasis vulgaris
0.000 0.239 0.761
I10-I15 Hypertensive diseases
0.000 0.243 0.757
E11.6 With other specified complications
0.000 0.262 0.738
E10.6 With other specified complications
0.000 0.268 0.732
E14.6 With other specified complications
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.284 0.716
E11.5 With peripheral circulatory complications
0.000 0.286 0.714
E16 Other disorders of pancreatic internal secretion
0.000 0.291 0.709
I22.8 Subsequent myocardial infarction of other sites
0.000 0.291 0.709
G36 Other acute disseminated demyelination
0.708 0.292 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.295 0.705
E14.5 With peripheral circulatory complications
0.000 0.296 0.704
G37.5 Concentric sclerosis [Balo]
0.702 0.298 0.000
G37.4 Subacute necrotising myelitis
0.702 0.298 0.000
G37.2 Central pontine myelinolysis
0.702 0.298 0.000
G37.1 Central demyelination of corpus callosum
0.702 0.298 0.000
G37.0 Diffuse sclerosis
0.702 0.298 0.000
E78.6 Lipoprotein deficiency
0.000 0.301 0.699
L43.8 Other lichen planus
0.000 0.310 0.690
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.312 0.688
E85 Amyloidosis
0.000 0.322 0.677
L42 Pityriasis rosea
0.000 0.330 0.670
E78.1 Pure hyperglyceridaemia
0.000 0.331 0.669
I15 Secondary hypertension
0.000 0.337 0.663
E78.3 Hyperchylomicronaemia
0.000 0.338 0.661
E16.2 Hypoglycaemia, unspecified
0.000 0.342 0.658
E78.4 Other hyperlipidaemia
0.000 0.344 0.656
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.352 0.648
E74 Other disorders of carbohydrate metabolism
0.000 0.357 0.643
E13.8 With unspecified complications
0.000 0.358 0.642
E13.7 With multiple complications
0.000 0.358 0.642
E13.6 With other specified complications
0.000 0.358 0.642
E13.5 With peripheral circulatory complications
0.000 0.358 0.642
E13.4 With neurological complications
0.000 0.358 0.642
E13.3 With ophthalmic complications
0.000 0.358 0.642
E13.2 With renal complications
0.000 0.358 0.642
E13.1 With ketoacidosis
0.000 0.358 0.642
E13.0 With coma
0.000 0.358 0.642
E11.4 With neurological complications
0.000 0.362 0.638
L44 Other papulosquamous disorders
0.000 0.374 0.626
L41 Parapsoriasis
0.000 0.374 0.626
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.374 0.626
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.376 0.624
I12 Hypertensive renal disease
0.000 0.388 0.612
I20.1 Angina pectoris with documented spasm
0.000 0.389 0.611
I23.8 Other current complications following acute myocardial infarction
0.000 0.389 0.611
I15.1 Hypertension secondary to other renal disorders
0.000 0.394 0.606
L43.3 Subacute (active) lichen planus
0.000 0.400 0.600
L43.2 Lichenoid drug reaction
0.000 0.400 0.600
L43.1 Bullous lichen planus
0.000 0.400 0.600
L43.0 Hypertrophic lichen planus
0.000 0.400 0.600
E77 Disorders of glycoprotein metabolism
0.001 0.407 0.592
E76 Disorders of glycosaminoglycan metabolism
0.001 0.407 0.592
E72 Other disorders of amino-acid metabolism
0.001 0.407 0.592
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.407 0.592
E70 Disorders of aromatic amino-acid metabolism
0.001 0.407 0.592
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.407 0.592
E79 Disorders of purine and pyrimidine metabolism
0.000 0.407 0.592
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.416 0.584
I11 Hypertensive heart disease
0.000 0.420 0.580
E78.5 Hyperlipidaemia, unspecified
0.000 0.425 0.575
E85.9 Amyloidosis, unspecified
0.000 0.427 0.572
E11.3 With ophthalmic complications
0.000 0.430 0.570
E16.1 Other hypoglycaemia
0.000 0.432 0.568
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.445 0.555
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.445 0.555
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.445 0.555
I25.4 Coronary artery aneurysm
0.000 0.452 0.548
E15 Nondiabetic hypoglycaemic coma
0.000 0.454 0.546
I13 Hypertensive heart and renal disease
0.000 0.457 0.543
E84 Cystic fibrosis
0.001 0.457 0.542
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.463 0.537
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.468 0.532
I12.9 Hypertensive renal disease without renal failure
0.000 0.468 0.532
E00-E07 Disorders of thyroid gland
0.000 0.475 0.525
E40-E46 Malnutrition
0.000 0.476 0.524
Chapter IX Diseases of the circulatory system
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.0 Neuromyelitis optica [Devic]
0.512 0.488 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.489 0.511
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.491 0.509
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.491 0.509
E16.4 Abnormal secretion of gastrin
0.000 0.491 0.509
E16.3 Increased secretion of glucagon
0.000 0.491 0.509
G36.9 Acute disseminated demyelination, unspecified
0.508 0.492 0.000
G36.8 Other specified acute disseminated demyelination
0.508 0.492 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.508 0.492 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.497 0.503
E83 Disorders of mineral metabolism
0.397 0.497 0.106
E73 Lactose intolerance
0.001 0.499 0.500
I24.1 Dressler's syndrome
0.000 0.501 0.499
E11.8 With unspecified complications
0.000 0.502 0.497
E85.4 Organ-limited amyloidosis
0.000 0.507 0.493
E85.8 Other amyloidosis
0.000 0.514 0.486
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.514 0.486
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.514 0.486
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.514 0.486
E89.3 Postprocedural hypopituitarism
0.000 0.516 0.484
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.517 0.483
I15.8 Other secondary hypertension
0.000 0.524 0.476
I15.2 Hypertension secondary to endocrine disorders
0.000 0.524 0.476
I15.0 Renovascular hypertension
0.000 0.524 0.476
E85.3 Secondary systemic amyloidosis
0.000 0.525 0.474
E03 Other hypothyroidism
0.000 0.526 0.474
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.539 0.461
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.539 0.461
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.539 0.461
E74.2 Disorders of galactose metabolism
0.000 0.539 0.461
E74.1 Disorders of fructose metabolism
0.000 0.539 0.461
E74.0 Glycogen storage disease
0.000 0.539 0.461
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.539 0.460
E03.9 Hypothyroidism, unspecified
0.000 0.542 0.458
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.545 0.455
L41.9 Parapsoriasis, unspecified
0.000 0.551 0.449
L41.8 Other parapsoriasis
0.000 0.551 0.449
L41.5 Retiform parapsoriasis
0.000 0.551 0.449
L41.4 Large plaque parapsoriasis
0.000 0.551 0.449
L41.3 Small plaque parapsoriasis
0.000 0.551 0.449
L41.2 Lymphomatoid papulosis
0.000 0.551 0.449
L41.1 Pityriasis lichenoides chronica
0.000 0.551 0.449
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.551 0.449
L44.9 Papulosquamous disorder, unspecified
0.000 0.551 0.449
L44.8 Other specified papulosquamous disorders
0.000 0.551 0.449
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.551 0.449
L44.3 Lichen ruber moniliformis
0.000 0.551 0.449
L44.2 Lichen striatus
0.000 0.551 0.449
L44.1 Lichen nitidus
0.000 0.551 0.449
L44.0 Pityriasis rubra pilaris
0.000 0.551 0.449
I15.9 Seconday hypertension, unspecified
0.000 0.555 0.445
E05.9 Thyrotoxicosis, unspecified
0.000 0.574 0.426
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.575 0.425
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.575 0.425
E70.3 Albinism
0.001 0.575 0.425
E70.2 Disorders of tyrosine metabolism
0.001 0.575 0.425
E70.1 Other hyperphenylalaninaemias
0.001 0.575 0.425
E70.0 Classical phenylketonuria
0.001 0.575 0.425
E71.3 Disorders of fatty-acid metabolism
0.001 0.575 0.425
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.575 0.425
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.575 0.425
E71.0 Maple-syrup-urine disease
0.001 0.575 0.425
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.575 0.425
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.575 0.425
E72.5 Disorders of glycine metabolism
0.001 0.575 0.425
E72.4 Disorders of ornithine metabolism
0.001 0.575 0.425
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.575 0.425
E72.2 Disorders of urea cycle metabolism
0.001 0.575 0.425
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.575 0.425
E72.0 Disorders of amino-acid transport
0.001 0.575 0.425
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.575 0.425
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.575 0.425
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.575 0.425
E76.2 Other mucopolysaccharidoses
0.001 0.575 0.425
E76.1 Mucopolysaccharidosis, type II
0.001 0.575 0.425
E76.0 Mucopolysaccharidosis, type I
0.001 0.575 0.425
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.575 0.425
E77.8 Other disorders of glycoprotein metabolism
0.001 0.575 0.425
E77.1 Defects in glycoprotein degradation
0.001 0.575 0.425
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.575 0.425
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.575 0.425
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.575 0.425
E79.1 Lesch-Nyhan syndrome
0.000 0.575 0.425
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.575 0.425
E75.6 Lipid storage disorder, unspecified
0.001 0.581 0.419
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.581 0.419
E75.3 Sphingolipidosis, unspecified
0.001 0.581 0.419
E75.2 Other sphingolipidosis
0.001 0.581 0.419
E75.1 Other gangliosidosis
0.001 0.581 0.419
E75.0 GM2 gangliosidosis
0.001 0.581 0.419
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.583 0.417
E75.5 Other lipid storage disorders
0.000 0.589 0.410
K90 Intestinal malabsorption
0.000 0.590 0.410
E65-E68 Obesity and other hyperalimentation
0.000 0.597 0.403
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.611 0.389
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.611 0.389
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.611 0.389
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.611 0.389
E84.8 Cystic fibrosis with other manifestations
0.001 0.611 0.389
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.611 0.389
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.611 0.389
E88 Other metabolic disorders
0.001 0.611 0.388
I12.0 Hypertensive renal disease with renal failure
0.000 0.611 0.389
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.614 0.385
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.614 0.385
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.614 0.385
E89.5 Postprocedural testicular hypofunction
0.000 0.614 0.385
E89.1 Postprocedural hypoinsulinaemia
0.000 0.614 0.385
E50-E64 Other nutritional deficiencies
0.000 0.618 0.382
E83.3 Disorders of phosphorus metabolism
0.349 0.620 0.031
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.623 0.377
E00 Congenital iodine-deficiency syndrome
0.000 0.623 0.377
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.624 0.375
E45 Retarded development following protein-energy malnutrition
0.000 0.624 0.375
E43 Unspecified severe protein-energy malnutrition
0.000 0.624 0.375
E42 Marasmic kwashiorkor
0.000 0.624 0.375
E41 Nutritional marasmus
0.000 0.624 0.375
E40 Kwashiorkor
0.000 0.624 0.375
I00-I02 Acute rheumatic fever
0.000 0.628 0.372
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.636 0.364
E83.9 Disorder of mineral metabolism, unspecified
0.285 0.639 0.076
E83.8 Other disorders of mineral metabolism
0.285 0.639 0.076
E83.2 Disorders of zinc metabolism
0.285 0.639 0.076
E83.0 Disorders of copper metabolism
0.285 0.639 0.076
E73.8 Other lactose intolerance
0.001 0.641 0.359
E73.1 Secondary lactase deficiency
0.001 0.641 0.359
E73.0 Congenital lactase deficiency
0.001 0.641 0.359
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.655 0.345
E89.4 Postprocedural ovarian failure
0.000 0.655 0.345
E80.6 Other disorders of bilirubin metabolism
0.000 0.655 0.345
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.656 0.344
E03.5 Myxoedema coma
0.000 0.660 0.340
E03.4 Atrophy of thyroid (acquired)
0.000 0.660 0.340
E03.3 Postinfectious hypothyroidism
0.000 0.660 0.340
E03.1 Congenital hypothyroidism without goitre
0.000 0.660 0.340
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.660 0.340
E84.9 Cystic fibrosis, unspecified
0.001 0.661 0.338
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.670 0.330
E80.5 Crigler-Najjar syndrome
0.000 0.670 0.330
E80.3 Defects of catalase and peroxydase
0.000 0.670 0.330
E80.2 Other porphyria
0.000 0.670 0.330
E80.1 Porphyria cutanea tarda
0.000 0.670 0.330
E80.0 Hereditary erythropoietic porphyria
0.000 0.670 0.330
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.672 0.328
E05.5 Thyroid crisis or storm
0.000 0.674 0.326
E05.4 Thyrotoxicosis factitia
0.000 0.674 0.326
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.674 0.326
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.674 0.326
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.676 0.324
E89.2 Postprocedural hypoparathyroidism
0.000 0.678 0.322
E88.2 Lipomatosis, not elsewhere classified
0.001 0.685 0.314
E07 Other disorders of thyroid
0.000 0.686 0.314
E06 Thyroiditis
0.000 0.694 0.306
E46 Unspecified protein-energy malnutrition
0.000 0.698 0.301
K90.9 Intestinal malabsorption, unspecified
0.000 0.703 0.297
K90.3 Pancreatic steatorrhoea
0.000 0.706 0.294
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.706 0.294
K90.1 Tropical sprue
0.000 0.706 0.294
K90.8 Other intestinal malabsorption
0.000 0.711 0.289
E61 Deficiency of other nutrient elements
0.000 0.711 0.289
E67 Other hyperalimentation
0.000 0.711 0.289
E68 Sequelae of hyperalimentation
0.000 0.711 0.289
E88.8 Other specified metabolic disorders
0.001 0.720 0.279
E65 Localised adiposity
0.000 0.721 0.279
E88.9 Metabolic disorder, unspecified
0.001 0.721 0.278
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.722 0.278
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.726 0.274
E63 Other nutritional deficiencies
0.000 0.726 0.274
E56 Other vitamin deficiencies
0.000 0.726 0.274
E51 Thiamine deficiency
0.000 0.726 0.274
E50 Vitamin A deficiency
0.000 0.726 0.274
E60 Dietary zinc deficiency
0.000 0.726 0.274
E59 Dietary selenium deficiency
0.000 0.726 0.274
E58 Dietary calcium deficiency
0.000 0.726 0.274
E54 Ascorbic acid deficiency
0.000 0.726 0.274
E52 Niacin deficiency [pellagra]
0.000 0.726 0.274
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.730 0.270
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.730 0.270
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.730 0.270
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.730 0.270
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.730 0.270
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.730 0.270
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.730 0.270
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.730 0.270
E44.1 Mild protein-energy malnutrition
0.000 0.730 0.269
E44.0 Moderate protein-energy malnutrition
0.000 0.730 0.269
E05.8 Other thyrotoxicosis
0.000 0.733 0.267
E73.9 Lactose intolerance, unspecified
0.001 0.733 0.266
I02 Rheumatic chorea
0.000 0.733 0.266
I01 Rheumatic fever with heart involvement
0.000 0.733 0.266
I00 Rheumatic fever without mention of heart involvement
0.000 0.733 0.266
E88.3 Tumour lysis syndrome
0.001 0.736 0.264
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.750 0.250
E20-E35 Disorders of other endocrine glands
0.000 0.755 0.245
E61.1 Iron deficiency
0.000 0.765 0.234
E07.1 Dyshormogenetic goitre
0.000 0.775 0.225
E07.0 Hypersecretion of calcitonin
0.000 0.775 0.225
E55 Vitamin D deficiency
0.000 0.775 0.225
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.775 0.224
E06.5 Other chronic thyroiditis
0.000 0.780 0.220
E06.4 Drug-induced thyroiditis
0.000 0.780 0.220
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.780 0.220
E06.1 Subacute thyroiditis
0.000 0.780 0.220
E06.0 Acute thyroiditis
0.000 0.780 0.220
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.781 0.218
E07.8 Other specified disorders of thyroid
0.000 0.786 0.214
E23 Hypofunction and other disorders of pituitary gland
0.000 0.787 0.213
E89.0 Postprocedural hypothyroidism
0.000 0.791 0.209
E03.8 Other specified hypothyroidism
0.001 0.792 0.208
E61.9 Deficiency of nutrient element, unspecified
0.000 0.792 0.207
E61.8 Deficiency of other specified nutrient elements
0.000 0.792 0.207
E61.7 Deficiency of multiple nutrient elements
0.000 0.792 0.207
E61.6 Vanadium deficiency
0.000 0.792 0.207
E61.5 Molybdenum deficiency
0.000 0.792 0.207
E61.4 Chromium deficiency
0.000 0.792 0.207
E61.3 Manganese deficiency
0.000 0.792 0.207
E61.0 Copper deficiency
0.000 0.792 0.207
E67.8 Other specified hyperalimentation
0.000 0.792 0.207
E67.3 Hypervitaminosis D
0.000 0.792 0.207
E67.2 Megavitamin-B6 syndrome
0.000 0.792 0.207
E67.1 Hypercarotenaemia
0.000 0.792 0.207
E67.0 Hypervitaminosis A
0.000 0.792 0.207
E06.9 Thyroiditis, unspecified
0.000 0.792 0.207
E50.9 Vitamin A deficiency, unspecified
0.000 0.803 0.197
E50.8 Other manifestations of vitamin A deficiency
0.000 0.803 0.197
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.803 0.197
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.803 0.197
E50.5 Vitamin A deficiency with night blindness
0.000 0.803 0.197
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.803 0.197
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.803 0.197
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.803 0.197
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.803 0.197
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.803 0.197
E51.9 Thiamine deficiency, unspecified
0.000 0.803 0.197
E51.8 Other manifestations of thiamine deficiency
0.000 0.803 0.197
E51.2 Wernicke's encephalopathy
0.000 0.803 0.197
E51.1 Beriberi
0.000 0.803 0.197
E56.9 Vitamin deficiency, unspecified
0.000 0.803 0.197
E56.8 Deficiency of other vitamins
0.000 0.803 0.197
E56.1 Deficiency of vitamin K
0.000 0.803 0.197
E56.0 Deficiency of vitamin E
0.000 0.803 0.197
E63.9 Nutritional deficiency, unspecified
0.000 0.803 0.197
E63.8 Other specified nutritional deficiencies
0.000 0.803 0.197
E63.1 Imbalance of constituents of food intake
0.000 0.803 0.197
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.803 0.197
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.803 0.197
E64.8 Sequelae of other nutritional deficiencies
0.000 0.803 0.197
E64.3 Sequelae of rickets
0.000 0.803 0.197
E64.2 Sequelae of vitamin C deficiency
0.000 0.803 0.197
E64.1 Sequelae of vitamin A deficiency
0.000 0.803 0.197
E64.0 Sequelae of protein-energy malnutrition
0.000 0.803 0.197
E83.4 Disorders of magnesium metabolism
0.121 0.807 0.072
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.809 0.191
I01.8 Other acute rheumatic heart disease
0.000 0.809 0.191
I01.2 Acute rheumatic myocarditis
0.000 0.809 0.191
I01.1 Acute rheumatic endocarditis
0.000 0.809 0.191
I01.0 Acute rheumatic pericarditis
0.000 0.809 0.191
I02.9 Rheumatic chorea without heart involvement
0.000 0.809 0.191
I02.0 Rheumatic chorea with heart involvement
0.000 0.809 0.191
E61.2 Magnesium deficiency
0.000 0.810 0.190
E22 Hyperfunction of pituitary gland
0.000 0.815 0.185
E23.2 Diabetes insipidus
0.000 0.819 0.181
E07.9 Disorder of thyroid, unspecified
0.000 0.821 0.179
E23.6 Other disorders of pituitary gland
0.000 0.822 0.178
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.824 0.176
E32 Diseases of thymus
0.000 0.824 0.176
E31 Polyglandular dysfunction
0.000 0.824 0.176
E30 Disorders of puberty, not elsewhere classified
0.000 0.824 0.176
E25 Adrenogenital disorders
0.000 0.824 0.176
E26 Hyperaldosteronism
0.000 0.828 0.172
E06.3 Autoimmune thyroiditis
0.000 0.831 0.168
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.832 0.168
E83.5 Disorders of calcium metabolism
0.148 0.833 0.019
E23.7 Disorder of pituitary gland, unspecified
0.000 0.835 0.165
E20 Hypoparathyroidism
0.000 0.836 0.164
E80.4 Gilbert's syndrome
0.000 0.836 0.164
E24 Cushing's syndrome
0.000 0.837 0.163
E29 Testicular dysfunction
0.000 0.837 0.163
E55.0 Rickets, active
0.000 0.838 0.161
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.844 0.156
I28 Other diseases of pulmonary vessels
0.001 0.845 0.154
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.845 0.154
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.847 0.153
E23.1 Drug-induced hypopituitarism
0.000 0.847 0.153
E28 Ovarian dysfunction
0.000 0.850 0.150
M45 Ankylosing spondylitis
0.000 0.857 0.143
I27 Other pulmonary heart diseases
0.000 0.860 0.139
H66.3 Other chronic suppurative otitis media
0.000 0.862 0.138
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.867 0.133
E22.8 Other hyperfunction of pituitary gland
0.000 0.867 0.133
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.870 0.130
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.871 0.129
E22.1 Hyperprolactinaemia
0.000 0.873 0.127
I27.9 Pulmonary heart disease, unspecified
0.000 0.873 0.127
E25.9 Adrenogenital disorder, unspecified
0.000 0.874 0.126
E25.8 Other adrenogenital disorders
0.000 0.874 0.126
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.874 0.126
E30.9 Disorder of puberty, unspecified
0.000 0.874 0.126
E30.8 Other disorders of puberty
0.000 0.874 0.126
E30.1 Precocious puberty
0.000 0.874 0.126
E30.0 Delayed puberty
0.000 0.874 0.126
E31.9 Polyglandular dysfunction, unspecified
0.000 0.874 0.126
E31.8 Other polyglandular dysfunction
0.000 0.874 0.126
E31.1 Polyglandular hyperfunction
0.000 0.874 0.126
E31.0 Autoimmune polyglandular failure
0.000 0.874 0.126
E32.9 Disease of thymus, unspecified
0.000 0.874 0.126
E32.8 Other diseases of thymus
0.000 0.874 0.126
E32.1 Abscess of thymus
0.000 0.874 0.126
E32.0 Persistent hyperplasia of thymus
0.000 0.874 0.126
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.874 0.126
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.874 0.126
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.874 0.126
E34 Other endocrine disorders
0.000 0.874 0.125
H66 Suppurative and unspecified otitis media
0.000 0.875 0.125
H71 Cholesteatoma of middle ear
0.000 0.876 0.124
H65-H75 Diseases of middle ear and mastoid
0.000 0.876 0.124
E53 Deficiency of other B group vitamins
0.000 0.876 0.123
E26.9 Hyperaldosteronism, unspecified
0.000 0.877 0.123
E26.8 Other hyperaldosteronism
0.000 0.877 0.123
E26.1 Secondary hyperaldosteronism
0.000 0.877 0.123
I05-I09 Chronic rheumatic heart diseases
0.000 0.878 0.122
E22.0 Acromegaly and pituitary gigantism
0.000 0.881 0.119
E26.0 Primary hyperaldosteronism
0.000 0.881 0.119
E66 Obesity
0.000 0.881 0.119
E20.8 Other hypoparathyroidism
0.000 0.882 0.118
E20.1 Pseudohypoparathyroidism
0.000 0.882 0.118
E20.0 Idiopathic hypoparathyroidism
0.000 0.882 0.118
E24.8 Other Cushing's syndrome
0.000 0.883 0.117
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.883 0.117

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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