TreeWAS – Variant ID: rs113011189

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.146	0.854
M81.9 Osteoporosis, unspecified	0.194	0.806
M81.98 Osteoporosis, unspecified (Other)	0.224	0.776
M81.90 Osteoporosis, unspecified (Multiple sites)	0.323	0.677
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.393	0.607
M81.96 Osteoporosis, unspecified (Lower leg)	0.422	0.578
M81.94 Osteoporosis, unspecified (Hand)	0.422	0.578
M81.93 Osteoporosis, unspecified (Forearm)	0.422	0.578
M81.92 Osteoporosis, unspecified (Upper arm)	0.422	0.578
M81.91 Osteoporosis, unspecified (Shoulder region)	0.422	0.578
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.480	0.520
M81 Osteoporosis without pathological fracture	0.617	0.383
M81.8 Other osteoporosis	0.725	0.275
M81.6 Localised osteoporosis [Lequesne]	0.725	0.275
M81.5 Idiopathic osteoporosis	0.725	0.275
M81.3 Postsurgical malabsorption osteoporosis	0.725	0.275
M81.1 Postoophorectomy osteoporosis	0.725	0.275
M81.0 Postmenopausal osteoporosis	0.725	0.275
M81.2 Osteoporosis of disuse	0.727	0.272
M81.4 Drug-induced osteoporosis	0.753	0.247
Chapter XV Pregnancy, childbirth and the puerperium	0.802	0.198
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.803	0.197
M81.08 Postmenopausal osteoporosis (Other)	0.803	0.197
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.803	0.197
M81.06 Postmenopausal osteoporosis (Lower leg)	0.803	0.197
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.803	0.197
M81.04 Postmenopausal osteoporosis (Hand)	0.803	0.197
M81.03 Postmenopausal osteoporosis (Forearm)	0.803	0.197
M81.02 Postmenopausal osteoporosis (Upper arm)	0.803	0.197
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.803	0.197
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.803	0.197
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.803	0.197
M81.18 Postoophorectomy osteoporosis (Other)	0.803	0.197
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.803	0.197
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.803	0.197
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.803	0.197
M81.14 Postoophorectomy osteoporosis (Hand)	0.803	0.197
M81.13 Postoophorectomy osteoporosis (Forearm)	0.803	0.197
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.803	0.197
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.803	0.197
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.803	0.197
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.803	0.197
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.803	0.197
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.803	0.197
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.803	0.197
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.803	0.197
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.803	0.197
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.803	0.197
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.803	0.197
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.803	0.197
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.803	0.197
M81.59 Idiopathic osteoporosis (Site unspecified)	0.803	0.197
M81.58 Idiopathic osteoporosis (Other)	0.803	0.197
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.803	0.197
M81.56 Idiopathic osteoporosis (Lower leg)	0.803	0.197
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.803	0.197
M81.54 Idiopathic osteoporosis (Hand)	0.803	0.197
M81.53 Idiopathic osteoporosis (Forearm)	0.803	0.197
M81.52 Idiopathic osteoporosis (Upper arm)	0.803	0.197
M81.51 Idiopathic osteoporosis (Shoulder region)	0.803	0.197
M81.50 Idiopathic osteoporosis (Multiple sites)	0.803	0.197
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.803	0.197
M81.68 Localized osteoporosis [Lequesne] (Other)	0.803	0.197
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.803	0.197
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.803	0.197
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.803	0.197
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.803	0.197
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.803	0.197
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.803	0.197
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.803	0.197
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.803	0.197
M81.89 Other osteoporosis (Site unspecified)	0.803	0.197
M81.88 Other osteoporosis (Other)	0.803	0.197
M81.87 Other osteoporosis (Ankle and foot)	0.803	0.197
M81.86 Other osteoporosis (Lower leg)	0.803	0.197
M81.85 Other osteoporosis (Pelvic region and thigh)	0.803	0.197
M81.84 Other osteoporosis (Hand)	0.803	0.197
M81.83 Other osteoporosis (Forearm)	0.803	0.197
M81.82 Other osteoporosis (Upper arm)	0.803	0.197
M81.81 Other osteoporosis (Shoulder region)	0.803	0.197
M81.80 Other osteoporosis (Multiple sites)	0.803	0.197
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.803	0.197
O36 Maternal care for other known or suspected foetal problems	0.804	0.196
M81.29 Osteoporosis of disuse (Site unspecified)	0.804	0.195
M81.28 Osteoporosis of disuse (Other)	0.804	0.195
M81.27 Osteoporosis of disuse (Ankle and foot)	0.804	0.195
M81.26 Osteoporosis of disuse (Lower leg)	0.804	0.195
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.804	0.195
M81.24 Osteoporosis of disuse (Hand)	0.804	0.195
M81.23 Osteoporosis of disuse (Forearm)	0.804	0.195
M81.22 Osteoporosis of disuse (Upper arm)	0.804	0.195
M81.21 Osteoporosis of disuse (Shoulder region)	0.804	0.195
O60-O75 Complications of labour and delivery	0.806	0.194
M81.20 Osteoporosis of disuse (Multiple sites)	0.807	0.193
O20-O29 Other maternal disorders predominantly related to pregnancy	0.808	0.192
O68 Labour and delivery complicated by foetal stress [distress]	0.809	0.191
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.809	0.191
O26 Maternal care for other conditions predominantly related to pregnancy	0.818	0.182
O16 Unspecified maternal hypertension	0.818	0.182
O70 Perineal laceration during delivery	0.818	0.182
O36.5 Maternal care for poor foetal growth	0.819	0.181
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.822	0.178
M81.49 Drug-induced osteoporosis (Site unspecified)	0.822	0.177
M81.48 Drug-induced osteoporosis (Other)	0.822	0.177
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.822	0.177
M81.46 Drug-induced osteoporosis (Lower leg)	0.822	0.177
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.822	0.177
M81.44 Drug-induced osteoporosis (Hand)	0.822	0.177
M81.43 Drug-induced osteoporosis (Forearm)	0.822	0.177
M81.42 Drug-induced osteoporosis (Upper arm)	0.822	0.177
M81.41 Drug-induced osteoporosis (Shoulder region)	0.822	0.177
O36.8 Maternal care for other specified foetal problems	0.826	0.174
O36.6 Maternal care for excessive foetal growth	0.827	0.173
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.828	0.172
O70.1 Second degree perineal laceration during delivery	0.829	0.171
O75 Other complications of labour and delivery, not elsewhere classified	0.831	0.169
O41 Other disorders of amniotic fluid and membranes	0.833	0.167
O23 Infections of genito-urinary tract in pregnancy	0.834	0.166
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.834	0.166
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.835	0.165
O70.9 Perineal laceration during delivery, unspecified	0.835	0.165
O26.8 Other specified pregnancy-related conditions	0.835	0.165
O73 Retained placenta and membranes, without haemorrhage	0.835	0.165
O46 Antepartum haemorrhage, not elsewhere classified	0.835	0.165
O36.9 Maternal care for foetal problem, unspecified	0.836	0.164
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.837	0.163
O61 Failed induction of labour	0.839	0.161
O00-O08 Pregnancy with abortive outcome	0.839	0.161
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.840	0.160
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.841	0.159
O26.9 Pregnancy-related condition, unspecified	0.842	0.158
O36.4 Maternal care for intra-uterine death	0.843	0.157
O36.0 Maternal care for rhesus isoimmunisation	0.848	0.152
O41.0 Oligohydramnios	0.848	0.152
M81.40 Drug-induced osteoporosis (Multiple sites)	0.850	0.149
O48 Prolonged pregnancy	0.853	0.147
O63 Long labour	0.853	0.147
M80-M85 Disorders of bone density and structure	0.853	0.147
O46.9 Antepartum haemorrhage, unspecified	0.853	0.147
O20 Haemorrhage in early pregnancy	0.854	0.146
O03 Spontaneous abortion	0.855	0.145
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.855	0.145
O36.3 Maternal care for signs of foetal hypoxia	0.855	0.144
O75.0 Maternal distress during labour and delivery	0.856	0.144
O15 Eclampsia	0.859	0.141
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.859	0.141
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.859	0.141
O36.2 Maternal care for hydrops foetalis	0.859	0.141
O36.1 Maternal care for other isoimmunisation	0.859	0.141
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.860	0.140
O73.0 Retained placenta, without haemorrhage	0.860	0.140
O45 Premature separation of placenta [abruptio placentae]	0.860	0.140
O74 Complications of anaesthesia during labour and delivery	0.861	0.139
O65 Obstructed labour due to maternal pelvic abnormality	0.861	0.139
O60 Preterm delivery	0.861	0.139
O03.4 Incomplete, without complication	0.862	0.138
O29 Complications of anaesthesia during pregnancy	0.862	0.138
O22 Venous complications in pregnancy	0.862	0.138
O25 Malnutrition in pregnancy	0.862	0.138
O23.5 Infections of the genital tract in pregnancy	0.862	0.138
O31 Complications specific to multiple gestation	0.863	0.137
O47 False labour	0.863	0.137
O61.0 Failed medical induction of labour	0.863	0.137
O23.4 Unspecified infection of urinary tract in pregnancy	0.864	0.136
O14.0 Moderate preeclampsia	0.865	0.135
O35 Maternal care for known or suspected foetal abnormality and damage	0.865	0.135
O32 Maternal care for known or suspected malpresentation of foetus	0.865	0.135
O24 Diabetes mellitus in pregnancy	0.865	0.134
O21 Excessive vomiting in pregnancy	0.866	0.134
O33 Maternal care for known or suspected disproportion	0.867	0.133
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.867	0.133
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.868	0.132
O28 Abnormal findings on antenatal screening of mother	0.868	0.132
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.869	0.131
O26.5 Maternal hypotension syndrome	0.869	0.131
O26.4 Herpes gestationis	0.869	0.131
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.869	0.131
O26.1 Low weight gain in pregnancy	0.869	0.131
O26.0 Excessive weight gain in pregnancy	0.869	0.131
O70.3 Fourth degree perineal laceration during delivery	0.869	0.131
O75.2 Pyrexia during labour, not elsewhere classified	0.870	0.130
O02 Other abnormal products of conception	0.871	0.129
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.872	0.128
O12.0 Gestational oedema	0.873	0.127
O14.1 Severe preeclampsia	0.874	0.126
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.875	0.125
O14.9 Preeclampsia, unspecified	0.876	0.124
O12.1 Gestational proteinuria	0.876	0.124
M80 Osteoporosis with pathological fracture	0.878	0.122
O26.2 Pregnancy care of habitual aborter	0.879	0.121
O75.9 Complication of labour and delivery, unspecified	0.879	0.121
O75.5 Delayed delivery after artificial rupture of membranes	0.879	0.121
O75.4 Other complications of obstetric surgery and procedures	0.879	0.121
O75.3 Other infection during labour	0.879	0.121
O75.1 Shock during or following labour and delivery	0.879	0.121
O70.2 Third degree perineal laceration during delivery	0.880	0.120
O63.0 Prolonged first stage (of labour)	0.880	0.120
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.880	0.120
O41.1 Infection of amniotic sac and membranes	0.880	0.120
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.880	0.119
O23.3 Infections of other parts of urinary tract in pregnancy	0.880	0.119
O23.2 Infections of urethra in pregnancy	0.880	0.119
O23.1 Infections of bladder in pregnancy	0.880	0.119
O23.0 Infections of kidney in pregnancy	0.880	0.119
O75.7 Vaginal delivery following previous Caesarean section	0.881	0.119
O14.2 HELLP syndrome	0.881	0.119
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.881	0.119
O46.0 Antepartum haemorrhage with coagulation defect	0.882	0.118
O64 Obstructed labour due to malposition and malpresentation of foetus	0.883	0.117
O75.8 Other specified complications of labour and delivery	0.884	0.116
O46.8 Other antepartum haemorrhage	0.884	0.115
O32.2 Maternal care for transverse and oblique lie	0.885	0.115
O61.9 Failed induction of labour, unspecified	0.885	0.115
O61.8 Other failed induction of labour	0.885	0.115
O61.1 Failed instrumental induction of labour	0.885	0.115
O08 Complications following abortion and ectopic and molar pregnancy	0.885	0.115
O07 Failed attempted abortion	0.885	0.115
O06 Unspecified abortion	0.885	0.115
O05 Other abortion	0.885	0.115
O01 Hydatidiform mole	0.885	0.115
O40 Polyhydramnios	0.885	0.115
O44 Placenta praevia	0.885	0.115
O12.2 Gestational oedema with proteinuria	0.885	0.115
O20.8 Other haemorrhage in early pregnancy	0.886	0.114
O41.8 Other specified disorders of amniotic fluid and membranes	0.887	0.113
O47.9 False labour, unspecified	0.888	0.112
M82 Osteoporosis in diseases classified elsewhere	0.889	0.111
O63.1 Prolonged second stage (of labour)	0.890	0.110
O85-O92 Complications predominantly related to the puerperium	0.891	0.108
O20.0 Threatened abortion	0.891	0.109
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.892	0.108
O72 Postpartum haemorrhage	0.892	0.108
M85 Other disorders of bone density and structure	0.893	0.107
O63.2 Delayed delivery of second twin, triplet, etc.	0.894	0.106
M83 Adult osteomalacia	0.894	0.106
O30 Multiple gestation	0.894	0.105
O62 Abnormalities of forces of labour	0.895	0.105
O32.1 Maternal care for breech presentation	0.895	0.105
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.895	0.104
O03.8 Complete or unspecified, with other and unspecified complications	0.895	0.104
O03.7 Complete or unspecified, complicated by embolism	0.895	0.104
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.895	0.104
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.895	0.104
O03.3 Incomplete, with other and unspecified complications	0.895	0.104
O03.2 Incomplete, complicated by embolism	0.895	0.104
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.895	0.104
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.895	0.104
O02.0 Blighted ovum and nonhydatidiform mole	0.896	0.104
O45.9 Premature separation of placenta, unspecified	0.897	0.103
M80.0 Postmenopausal osteoporosis with pathological fracture	0.898	0.102
O15.9 Eclampsia, unspecified as to time period	0.898	0.101
O15.2 Eclampsia in the puerperium	0.898	0.101
O15.1 Eclampsia in labour	0.898	0.101
O15.0 Eclampsia in pregnancy	0.898	0.101
O45.8 Other premature separation of placenta	0.899	0.100
O45.0 Premature separation of placenta with coagulation defect	0.899	0.100
O60.3 Preterm delivery without spontaneous labour	0.900	0.100
O60.2 Preterm spontaneous labour with term delivery	0.900	0.100
O60.1 Preterm spontaneous labour with preterm delivery	0.900	0.100
O60.0 Preterm labour without delivery	0.900	0.100
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.900	0.100
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.900	0.100
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.900	0.100
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.900	0.100
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.900	0.100
O65.2 Obstructed labour due to pelvic inlet contraction	0.900	0.100
O65.1 Obstructed labour due to generally contracted pelvis	0.900	0.100
O65.0 Obstructed labour due to deformed pelvis	0.900	0.100
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.900	0.100
O74.8 Other complications of anaesthesia during labour and delivery	0.900	0.100
O74.7 Failed or difficult intubation during labour and delivery	0.900	0.100
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.900	0.100
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.900	0.100
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.900	0.100
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.900	0.100
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.900	0.100
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.900	0.100
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.900	0.100
O32.0 Maternal care for unstable lie	0.901	0.099
O22.9 Venous complication in pregnancy, unspecified	0.901	0.099
O22.8 Other venous complications in pregnancy	0.901	0.099
O22.5 Cerebral venous thrombosis in pregnancy	0.901	0.099
O22.4 Haemorrhoids in pregnancy	0.901	0.099
O22.3 Deep phlebothrombosis in pregnancy	0.901	0.099
O22.2 Superficial thrombophlebitis in pregnancy	0.901	0.099
O22.1 Genital varices in pregnancy	0.901	0.099
O22.0 Varicose veins of lower extremity in pregnancy	0.901	0.099
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.901	0.099
O29.8 Other complications of anaesthesia during pregnancy	0.901	0.099
O29.6 Failed or difficult intubation during pregnancy	0.901	0.099
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.901	0.099
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.901	0.099
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.901	0.099
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.901	0.099
O29.1 Cardiac complications of anaesthesia during pregnancy	0.901	0.099
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.901	0.099
O20.9 Haemorrhage in early pregnancy, unspecified	0.901	0.099
O31.8 Other complications specific to multiple gestation	0.901	0.098
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.901	0.098
O31.1 Continuing pregnancy after abortion of one foetus or more	0.901	0.098
O31.0 Papyraceous foetus	0.901	0.098
O66 Other obstructed labour	0.902	0.098
O21.0 Mild hyperemesis gravidarum	0.902	0.097
O94-O99 Other obstetric conditions, not elsewhere classified	0.903	0.097
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.903	0.097
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.903	0.097
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.903	0.097
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.903	0.097
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.903	0.097
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.903	0.097
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.903	0.097
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.903	0.097
O32.9 Maternal care for malpresentation of foetus, unspecified	0.903	0.097
O32.6 Maternal care for compound presentation	0.903	0.097
M80.9 Unspecified osteoporosis with pathological fracture	0.903	0.097
O24.3 Pre-existing diabetes mellitus, unspecified	0.903	0.097
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.903	0.097
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.903	0.097
O21.8 Other vomiting complicating pregnancy	0.904	0.096
O21.2 Late vomiting of pregnancy	0.904	0.096
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.904	0.096
O33.8 Maternal care for disproportion of other origin	0.904	0.095
O33.7 Maternal care for disproportion due to other foetal deformities	0.904	0.095
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.904	0.095
O33.5 Maternal care for disproportion due to unusually large foetus	0.904	0.095
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.904	0.095
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.904	0.095
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.904	0.095
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.904	0.095
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.904	0.095
O67.8 Other intrapartum haemorrhage	0.905	0.095
O67.0 Intrapartum haemorrhage with coagulation defect	0.905	0.095
O02.1 Missed abortion	0.905	0.095
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.905	0.095
O28.8 Other abnormal findings on antenatal screening of mother	0.905	0.095
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.905	0.095
O28.4 Abnormal radiological finding on antenatal screening of mother	0.905	0.095
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.905	0.095
O28.2 Abnormal cytological finding on antenatal screening of mother	0.905	0.095
O28.0 Abnormal haematological finding on antenatal screening of mother	0.905	0.095
O04 Medical abortion	0.906	0.094
O02.9 Abnormal product of conception, unspecified	0.908	0.092
O02.8 Other specified abnormal products of conception	0.908	0.092
O47.1 False labour at or after 37 completed weeks of gestation	0.908	0.092
O42 Premature rupture of membranes	0.908	0.092
O33.9 Maternal care for disproportion, unspecified	0.908	0.091
O21.9 Vomiting of pregnancy, unspecified	0.909	0.091
O24.9 Diabetes mellitus in pregnancy, unspecified	0.909	0.091
O63.9 Long labour, unspecified	0.909	0.091
O32.3 Maternal care for face, brow and chin presentation	0.910	0.090
O24.4 Diabetes mellitus arising in pregnancy	0.911	0.089
O70.0 First degree perineal laceration during delivery	0.911	0.089
O67.9 Intrapartum haemorrhage, unspecified	0.911	0.089
O32.8 Maternal care for other malpresentation of foetus	0.911	0.089
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.911	0.088
O43 Placental disorders	0.911	0.088
O71 Other obstetric trauma	0.911	0.088
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.912	0.088
M80.8 Other osteoporosis with pathological fracture	0.912	0.088
M80.4 Drug-induced osteoporosis with pathological fracture	0.912	0.088
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.912	0.088
M80.2 Osteoporosis of disuse with pathological fracture	0.912	0.088
O03.9 Complete or unspecified, without complication	0.912	0.088
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.914	0.086
O47.0 False labour before 37 completed weeks of gestation	0.914	0.086
M82.1 Osteoporosis in endocrine disorders	0.914	0.086
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.915	0.085
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.915	0.085
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.915	0.085
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.915	0.085
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.915	0.085
M80.5 Idiopathic osteoporosis with pathological fracture	0.915	0.085
O00 Ectopic pregnancy	0.916	0.084
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.916	0.084
O64.8 Obstructed labour due to other malposition and malpresentation	0.916	0.084
O64.5 Obstructed labour due to compound presentation	0.916	0.084
O64.4 Obstructed labour due to shoulder presentation	0.916	0.084
O64.3 Obstructed labour due to brow presentation	0.916	0.084
O64.2 Obstructed labour due to face presentation	0.916	0.084
M85.8 Other specified disorders of bone density and structure	0.917	0.083
O01.9 Hydatidiform mole, unspecified	0.917	0.083
O01.1 Incomplete and partial hydatidiform mole	0.917	0.083
O01.0 Classical hydatidiform mole	0.917	0.083
O05.9 Complete or unspecified, without complication	0.917	0.083
O05.8 Complete or unspecified, with other and unspecified complications	0.917	0.083
O05.7 Complete or unspecified, complicated by embolism	0.917	0.083
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.917	0.083
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.917	0.083
O05.4 Incomplete, without complication	0.917	0.083
O05.3 Incomplete, with other and unspecified complications	0.917	0.083
O05.2 Incomplete, complicated by embolism	0.917	0.083
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.917	0.083
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.917	0.083
O06.9 Complete or unspecified, without complication	0.917	0.083
O06.8 Complete or unspecified, with other and unspecified complications	0.917	0.083
O06.7 Complete or unspecified, complicated by embolism	0.917	0.083
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.917	0.083
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.917	0.083
O06.4 Incomplete, without complication	0.917	0.083
O06.3 Incomplete, with other and unspecified complications	0.917	0.083
O06.2 Incomplete, complicated by embolism	0.917	0.083
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.917	0.083
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.917	0.083
O07.9 Other and unspecified failed attempted abortion, without complication	0.917	0.083
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.917	0.083
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.917	0.083
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.917	0.083
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.917	0.083
O07.4 Failed medical abortion, without complication	0.917	0.083
O07.3 Failed medical abortion, with other and unspecified complications	0.917	0.083
O07.2 Failed medical abortion, complicated by embolism	0.917	0.083
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.917	0.083
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.917	0.083
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.917	0.083
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.917	0.083
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.917	0.083
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.917	0.083
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.917	0.083
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.917	0.083
O08.3 Shock following abortion and ectopic and molar pregnancy	0.917	0.083
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.917	0.083
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.917	0.083
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.917	0.083
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.917	0.082
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.918	0.082
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.918	0.082
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.919	0.081
O32.4 Maternal care for high head at term	0.919	0.080
O72.0 Third-stage haemorrhage	0.920	0.080
M82.8 Osteoporosis in other diseases classified elsewhere	0.920	0.080
M82.0 Osteoporosis in multiple myelomatosis	0.920	0.080
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.920	0.080
O34 Maternal care for known or suspected abnormality of pelvic organs	0.920	0.080
O90 Complications of the puerperium, not elsewhere classified	0.922	0.078
O92 Other disorders of breast and lactation associated with childbirth	0.922	0.078
O91 Infections of breast associated with childbirth	0.922	0.078
O89 Complications of anaesthesia during the puerperium	0.922	0.078
O88 Obstetric embolism	0.922	0.078
O62.3 Precipitate labour	0.922	0.078
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.922	0.078
O72.3 Postpartum coagulation defects	0.922	0.078
O44.0 Placenta praevia specified as without haemorrhage	0.922	0.077
M85.9 Disorder of bone density and structure, unspecified	0.923	0.076
M85.5 Aneurysmal bone cyst	0.923	0.076
M85.4 Solitary bone cyst	0.923	0.076
M85.3 Osteitis condensans	0.923	0.076
M85.2 Hyperostosis of skull	0.923	0.076
M85.1 Skeletal fluorosis	0.923	0.076
M83.9 Adult osteomalacia, unspecified	0.924	0.076
M83.8 Other adult osteomalacia	0.924	0.076
M83.5 Other drug-induced osteomalacia in adults	0.924	0.076
M83.4 Aluminum bone disease	0.924	0.076
M83.3 Adult osteomalacia due to malnutrition	0.924	0.076
M83.2 Adult osteomalacia due to malabsorption	0.924	0.076
M83.1 Senile osteomalacia	0.924	0.076
M83.0 Puerperal osteomalacia	0.924	0.076
M85.0 Fibrous dysplasia (monostotic)	0.924	0.076
O30.9 Multiple gestation, unspecified	0.924	0.076
O30.8 Other multiple gestation	0.924	0.076
O30.2 Quadruplet pregnancy	0.924	0.076
O30.1 Triplet pregnancy	0.924	0.076
O62.9 Abnormality of forces of labour, unspecified	0.924	0.076
O62.8 Other abnormalities of forces of labour	0.924	0.076
O80-O84 Delivery	0.925	0.074
O87 Venous complications in the puerperium	0.926	0.074
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.926	0.073
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.926	0.073
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.926	0.073
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.926	0.073
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.926	0.073
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.926	0.073
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.926	0.073
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.926	0.073
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.926	0.073
O62.1 Secondary uterine inertia	0.927	0.072
O85 Puerperal sepsis	0.929	0.071
M85.6 Other cyst of bone	0.930	0.070
O66.9 Obstructed labour, unspecified	0.930	0.070
O66.8 Other specified obstructed labour	0.930	0.070
O66.3 Obstructed labour due to other abnormalities of foetus	0.930	0.070
O66.2 Obstructed labour due to unusually large foetus	0.930	0.070
O66.1 Obstructed labour due to locked twins	0.930	0.070
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.930	0.070
O97 Death from sequelae of direct obstetric causes	0.930	0.070
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.930	0.070
O95 Obstetric death of unspecified cause	0.930	0.070
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.930	0.070
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.930	0.069
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.930	0.069
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.930	0.069
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.930	0.069
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.930	0.069
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.930	0.069
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.930	0.069
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.930	0.069
O69 Labour and delivery complicated by umbilical cord complications	0.931	0.069
O04.9 Complete or unspecified, without complication	0.931	0.069
O44.1 Placenta praevia with haemorrhage	0.932	0.068
O72.2 Delayed and secondary postpartum haemorrhage	0.932	0.068
O04.8 Complete or unspecified, with other and unspecified complications	0.932	0.067

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations