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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113319671
log Bayes Factor = 15.9526
Chromosome 4   position 30,514,952  (GRCh37) Explore rs113319671 on Ensembl!
Variant rs113319671 is part of Cluster X0139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.993 0.007 0.000
E70-E90 Metabolic disorders
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.991 0.009 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.974 0.026 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.966 0.034 0.000
Chapter II Neoplasms
0.964 0.036 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.964 0.036 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.964 0.036 0.000
E78.0 Pure hypercholesterolaemia
0.963 0.037 0.000
I25.2 Old myocardial infarction
0.962 0.038 0.000
M05-M14 Inflammatory polyarthropathies
0.962 0.038 0.000
I20 Angina pectoris
0.961 0.039 0.000
I25.1 Atherosclerotic heart disease
0.956 0.044 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.954 0.046 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.951 0.049 0.000
Chapter X Diseases of the respiratory system
0.951 0.049 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.949 0.051 0.000
N30-N39 Other diseases of urinary system
0.947 0.053 0.000
M45-M49 Spondylopathies
0.943 0.057 0.000
E10-E14 Diabetes mellitus
0.936 0.064 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.930 0.070 0.000
N60-N64 Disorders of breast
0.929 0.071 0.000
N39 Other disorders of urinary system
0.928 0.072 0.000
H53-H54 Visual disturbances and blindness
0.926 0.074 0.000
N72 Inflammatory disease of cervix uteri
0.925 0.075 0.000
D60-D64 Aplastic and other anaemias
0.925 0.075 0.000
M15-M19 Arthrosis
0.918 0.082 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.917 0.083 0.000
I60-I69 Cerebrovascular diseases
0.914 0.086 0.000
N39.4 Other specified urinary incontinence
0.913 0.087 0.000
J30-J39 Other diseases of upper respiratory tract
0.910 0.090 0.000
E83 Disorders of mineral metabolism
0.910 0.090 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.908 0.092 0.000
I20.9 Angina pectoris, unspecified
0.902 0.098 0.000
M13 Other arthritis
0.896 0.104 0.000
Z45 Adjustment and management of implanted device
0.895 0.105 0.000
I30-I52 Other forms of heart disease
0.894 0.106 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.893 0.107 0.000
M17 Gonarthrosis [arthrosis of knee]
0.891 0.109 0.000
M17.9 Gonarthrosis, unspecified
0.886 0.114 0.000
N60 Benign mammary dysplasia
0.885 0.115 0.000
M47 Spondylosis
0.883 0.117 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.879 0.121 0.000
D64 Other anaemias
0.875 0.125 0.000
I20.0 Unstable angina
0.873 0.127 0.000
D50-D53 Nutritional anaemias
0.871 0.129 0.000
Chapter XX External causes of morbidity and mortality
0.870 0.130 0.000
Z48 Other surgical follow-up care
0.868 0.132 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.867 0.133 0.000
H53 Visual disturbances
0.857 0.143 0.000
E10 Insulin-dependent diabetes mellitus
0.851 0.149 0.000
J32 Chronic sinusitis
0.849 0.151 0.000
M13.9 Arthritis, unspecified
0.849 0.151 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.849 0.151 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.848 0.152 0.000
Z96 Presence of other functional implants
0.848 0.152 0.000
I69 Sequelae of cerebrovascular disease
0.845 0.155 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.844 0.156 0.000
D64.9 Anaemia, unspecified
0.840 0.160 0.000
I21 Acute myocardial infarction
0.839 0.160 0.000
Chapter VI Diseases of the nervous system
0.839 0.161 0.000
I73 Other peripheral vascular diseases
0.837 0.163 0.000
E11 Non-insulin-dependent diabetes mellitus
0.836 0.164 0.000
Z85 Personal history of malignant neoplasm
0.834 0.166 0.000
I51 Complications and ill-defined descriptions of heart disease
0.826 0.174 0.000
Z45.8 Adjustment and management of other implanted devices
0.824 0.176 0.000
Z72 Problems related to lifestyle
0.823 0.177 0.000
J34 Other disorders of nose and nasal sinuses
0.822 0.178 0.000
J35 Chronic diseases of tonsils and adenoids
0.821 0.179 0.000
Z95.0 Presence of cardiac pacemaker
0.821 0.179 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.820 0.180 0.000
N60.2 Fibroadenosis of breast
0.819 0.181 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.816 0.184 0.000
M70-M79 Other soft tissue disorders
0.814 0.186 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.812 0.188 0.000
D00-D09 In situ neoplasms
0.811 0.189 0.000
H52 Disorders of refraction and accommodation
0.811 0.189 0.000
H43-H45 Disorders of vitreous body and globe
0.810 0.190 0.000
Z54 Convalescence
0.810 0.190 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.809 0.191 0.000
J20-J22 Other acute lower respiratory infections
0.809 0.191 0.000
J32.9 Chronic sinusitis, unspecified
0.807 0.193 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.806 0.194 0.000
Z96.1 Presence of intraocular lens
0.804 0.196 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.804 0.196 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.804 0.196 0.000
I74 Arterial embolism and thrombosis
0.803 0.197 0.000
M06 Other rheumatoid arthritis
0.802 0.198 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.801 0.199 0.000
J09-J18 Influenza and pneumonia
0.800 0.200 0.000
C78.7 Secondary malignant neoplasm of liver
0.799 0.201 0.000
I25.5 Ischaemic cardiomyopathy
0.797 0.203 0.000
I51.7 Cardiomegaly
0.797 0.203 0.000
M65-M68 Disorders of synovium and tendon
0.797 0.203 0.000
Z72.0 Tobacco use
0.797 0.203 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.796 0.204 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.796 0.204 0.000
N25-N29 Other disorders of kidney and ureter
0.794 0.206 0.000
E83.1 Disorders of iron metabolism
0.794 0.206 0.000
Z93 Artificial opening status
0.794 0.206 0.000
I22 Subsequent myocardial infarction
0.793 0.207 0.000
I21.9 Acute myocardial infarction, unspecified
0.789 0.211 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.788 0.212 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.788 0.212 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.787 0.213 0.000
N40-N51 Diseases of male genital organs
0.786 0.214 0.000
Z49 Care involving dialysis
0.785 0.215 0.000
I73.9 Peripheral vascular disease, unspecified
0.784 0.216 0.000
E20-E35 Disorders of other endocrine glands
0.783 0.217 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.783 0.217 0.000
D51 Vitamin B12 deficiency anaemia
0.780 0.220 0.000
Z89 Acquired absence of limb
0.779 0.221 0.000
S00-S09 Injuries to the head
0.779 0.221 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.777 0.223 0.000
M47.8 Other spondylosis
0.775 0.225 0.000
I80 Phlebitis and thrombophlebitis
0.775 0.225 0.000
D62 Acute posthaemorrhagic anaemia
0.773 0.227 0.000
I70 Atherosclerosis
0.773 0.227 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.772 0.228 0.000
H30-H36 Disorders of choroid and retina
0.772 0.228 0.000
Z94 Transplanted organ and tissue status
0.771 0.228 0.000
I05-I09 Chronic rheumatic heart diseases
0.770 0.229 0.000
Z48.8 Other specified surgical follow-up care
0.768 0.232 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.768 0.232 0.000
N17-N19 Renal failure
0.768 0.232 0.000
I77 Other disorders of arteries and arterioles
0.766 0.234 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.764 0.236 0.000
N73 Other female pelvic inflammatory diseases
0.764 0.236 0.000
E83.5 Disorders of calcium metabolism
0.764 0.236 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.761 0.239 0.000
I24 Other acute ischaemic heart diseases
0.761 0.239 0.000
Z50 Care involving use of rehabilitation procedures
0.760 0.240 0.000
Chapter I Certain infectious and parasitic diseases
0.759 0.241 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.758 0.242 0.000
N71 Inflammatory disease of uterus, except cervix
0.757 0.243 0.000
E10.9 Without complications
0.757 0.243 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.757 0.243 0.000
E50-E64 Other nutritional deficiencies
0.755 0.245 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.755 0.245 0.000
Z95.1 Presence of aortocoronary bypass graft
0.754 0.246 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.753 0.246 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.752 0.248 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.751 0.249 0.000
M47.9 Spondylosis, unspecified
0.751 0.249 0.000
I78 Diseases of capillaries
0.750 0.250 0.000
H50 Other strabismus
0.750 0.250 0.000
I67 Other cerebrovascular diseases
0.748 0.252 0.000
H54 Blindness and low vision
0.748 0.252 0.000
C50-C50 Malignant neoplasm of breast
0.746 0.254 0.000
I44 Atrioventricular and left bundle-branch block
0.744 0.256 0.000
Z73 Problems related to life-management difficulty
0.743 0.257 0.000
M50-M54 Other dorsopathies
0.742 0.258 0.000
H55-H59 Other disorders of eye and adnexa
0.741 0.259 0.000
C80 Malignant neoplasm without specification of site
0.740 0.260 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.740 0.260 0.000
Z03.4 Observation for suspected myocardial infarction
0.738 0.262 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.738 0.262 0.000
H53.1 Subjective visual disturbances
0.734 0.266 0.000
Z40 Prophylactic surgery
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.733 0.267 0.000
E11.9 Without complications
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
M11 Other crystal arthropathies
0.732 0.268 0.000
N60.0 Solitary cyst of breast
0.732 0.268 0.000
M40-M43 Deforming dorsopathies
0.731 0.269 0.000
Chapter V Mental and behavioural disorders
0.731 0.269 0.000
N39.0 Urinary tract infection, site not specified
0.730 0.270 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.730 0.270 0.000
M07 Psoriatic and enteropathic arthropathies
0.727 0.273 0.000
I71 Aortic aneurysm and dissection
0.726 0.274 0.000
J80 Adult respiratory distress syndrome
0.726 0.274 0.000
I38 Endocarditis, valve unspecified
0.726 0.274 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.725 0.275 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.725 0.275 0.000
Z74 Problems related to care-provider dependency
0.724 0.276 0.000
H53.0 Amblyopia ex anopsia
0.724 0.276 0.000
H21 Other disorders of iris and ciliary body
0.723 0.277 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.723 0.277 0.000
S80-S89 Injuries to the knee and lower leg
0.721 0.279 0.000
Z48.0 Attention to surgical dressings and sutures
0.721 0.279 0.000
E88 Other metabolic disorders
0.720 0.280 0.000
T66-T78 Other and unspecified effects of external causes
0.720 0.280 0.000
H20 Iridocyclitis
0.718 0.282 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M48 Other spondylopathies
0.715 0.284 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.715 0.285 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
M46 Other inflammatory spondylopathies
0.714 0.286 0.000
Z93.1 Gastrostomy status
0.713 0.287 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
H10-H13 Disorders of conjunctiva
0.710 0.290 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.710 0.290 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.709 0.291 0.000
M10 Gout
0.709 0.291 0.000
Z54.0 Convalescence following surgery
0.709 0.291 0.000
I63 Cerebral infarction
0.708 0.292 0.000
H52.1 Myopia
0.708 0.292 0.000
J22 Unspecified acute lower respiratory infection
0.707 0.293 0.000
M45 Ankylosing spondylitis
0.706 0.294 0.000
H25-H28 Disorders of lens
0.706 0.294 0.000
N75 Diseases of Bartholin's gland
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
C79 Secondary malignant neoplasm of other sites
0.705 0.295 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.704 0.296 0.000
J60-J70 Lung diseases due to external agents
0.704 0.296 0.000
C15-C26 Malignant neoplasms of digestive organs
0.704 0.296 0.000
N63 Unspecified lump in breast
0.703 0.297 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.703 0.297 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.702 0.298 0.000
I42 Cardiomyopathy
0.701 0.299 0.000
A00-A09 Intestinal infectious diseases
0.701 0.299 0.000
J35.0 Chronic tonsillitis
0.700 0.300 0.000
J35.1 Hypertrophy of tonsils
0.700 0.300 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.699 0.301 0.000
E78.8 Other disorders of lipoprotein metabolism
0.699 0.301 0.000
E78.6 Lipoprotein deficiency
0.699 0.301 0.000
E78.4 Other hyperlipidaemia
0.699 0.301 0.000
E78.3 Hyperchylomicronaemia
0.699 0.301 0.000
E78.2 Mixed hyperlipidaemia
0.699 0.301 0.000
E78.1 Pure hyperglyceridaemia
0.699 0.301 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.699 0.301 0.000
N60.3 Fibrosclerosis of breast
0.698 0.302 0.000
Z45.2 Adjustment and management of vascular access device
0.698 0.302 0.000
D55-D59 Haemolytic anaemias
0.698 0.302 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.698 0.302 0.000
E87.0 Hyperosmolality and hypernatraemia
0.698 0.302 0.000
Z97 Presence of other devices
0.696 0.304 0.000
I50 Heart failure
0.696 0.304 0.000
S20-S29 Injuries to the thorax
0.695 0.305 0.000
M47.2 Other spondylosis with radiculopathy
0.694 0.305 0.000
E10.3 With ophthalmic complications
0.694 0.306 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.693 0.307 0.000
Z84 Family history of other conditions
0.692 0.308 0.000
Z81 Family history of mental and behavioural disorders
0.692 0.308 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.691 0.308 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.691 0.308 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.691 0.309 0.000
N76 Other inflammation of vagina and vulva
0.691 0.309 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.691 0.309 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.691 0.309 0.000
I72 Other aneurysm
0.691 0.309 0.000
M19 Other arthrosis
0.691 0.309 0.000
D80-D89 Certain disorders involving the immune mechanism
0.690 0.310 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.690 0.310 0.000
M14 Arthropathies in other diseases classified elsewhere
0.689 0.310 0.000
M12 Other specific arthropathies
0.689 0.310 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.689 0.310 0.000
M08 Juvenile arthritis
0.689 0.310 0.000
M05 Seropositive rheumatoid arthritis
0.689 0.310 0.000
I20.1 Angina pectoris with documented spasm
0.689 0.311 0.000
D45 Polycythaemia vera
0.689 0.311 0.000
R47-R49 Symptoms and signs involving speech and voice
0.689 0.311 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.688 0.312 0.000
Z22 Carrier of infectious disease
0.687 0.313 0.000
Z29 Need for other prophylactic measures
0.687 0.313 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.687 0.313 0.000
N99-N99 Other disorders of the genitourinary system
0.687 0.313 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.687 0.313 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.684 0.316 0.000
T33-T35 Frostbite
0.684 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.316 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.684 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.316 0.000
S90-S99 Injuries to the ankle and foot
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
Z41 Procedures for purposes other than remedying health state
0.684 0.316 0.000
N00-N08 Glomerular diseases
0.683 0.317 0.000
H16 Keratitis
0.683 0.317 0.000
S00 Superficial injury of head
0.683 0.317 0.000
E78.5 Hyperlipidaemia, unspecified
0.682 0.317 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.682 0.318 0.000
Z52 Donors of organs and tissues
0.682 0.318 0.000
Z44 Fitting and adjustment of external prosthetic device
0.682 0.318 0.000
Z83 Family history of other specific disorders
0.682 0.318 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.682 0.318 0.000
Z95.3 Presence of xenogenic heart valve
0.680 0.320 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.679 0.321 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.679 0.321 0.000
N39.9 Disorder of urinary system, unspecified
0.679 0.321 0.000
N37 Urethral disorders in diseases classified elsewhere
0.679 0.321 0.000
N36 Other disorders of urethra
0.679 0.321 0.000
N34 Urethritis and urethral syndrome
0.679 0.321 0.000
N33 Bladder disorders in diseases classified elsewhere
0.679 0.321 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.679 0.321 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.679 0.321 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.678 0.322 0.000
Z43 Attention to artificial openings
0.676 0.323 0.000
M49 Spondylopathies in diseases classified elsewhere
0.676 0.324 0.000
E83.4 Disorders of magnesium metabolism
0.676 0.324 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.676 0.324 0.000
N70 Salpingitis and oophoritis
0.676 0.324 0.000
C44 Other malignant neoplasms of skin
0.675 0.325 0.000
N64 Other disorders of breast
0.675 0.325 0.000
Z02 Examination and encounter for administrative purposes
0.675 0.325 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.674 0.326 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.674 0.326 0.000
S70-S79 Injuries to the hip and thigh
0.674 0.326 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.672 0.328 0.000
C64-C68 Malignant neoplasms of urinary tract
0.671 0.328 0.000
E13 Other specified diabetes mellitus
0.671 0.329 0.000
E12 Malnutrition-related diabetes mellitus
0.671 0.329 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.671 0.329 0.000
G90-G99 Other disorders of the nervous system
0.671 0.329 0.000
D50 Iron deficiency anaemia
0.670 0.330 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.670 0.330 0.000
W00-W19 Falls
0.670 0.330 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
W20-W49 Exposure to inanimate mechanical forces
0.669 0.331 0.000
Z90.1 Acquired absence of breast(s)
0.669 0.331 0.000
Z80 Family history of malignant neoplasm
0.668 0.332 0.000
N18 Chronic renal failure
0.667 0.333 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.667 0.333 0.000
Z76 Persons encountering health services in other circumstances
0.666 0.333 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.666 0.333 0.000
G30-G32 Other degenerative diseases of the nervous system
0.666 0.334 0.000
H53.4 Visual field defects
0.666 0.334 0.000
N39.2 Orthostatic proteinuria, unspecified
0.666 0.334 0.000
N39.1 Persistent proteinuria, unspecified
0.666 0.334 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.666 0.334 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.666 0.334 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.664 0.336 0.000
N30 Cystitis
0.664 0.336 0.000
D61 Other aplastic anaemias
0.663 0.337 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.663 0.337 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.663 0.337 0.000
I21.4 Acute subendocardial myocardial infarction
0.663 0.337 0.000
I46 Cardiac arrest
0.661 0.339 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.661 0.339 0.000
M65 Synovitis and tenosynovitis
0.661 0.339 0.000
D03 Melanoma in situ
0.661 0.339 0.000
I33 Acute and subacute endocarditis
0.660 0.339 0.000
N62 Hypertrophy of breast
0.659 0.341 0.000
G40-G47 Episodic and paroxysmal disorders
0.659 0.341 0.000
M15 Polyarthrosis
0.658 0.342 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.658 0.342 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.658 0.342 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.658 0.342 0.000
E86 Volume depletion
0.657 0.343 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.657 0.343 0.000
H52.2 Astigmatism
0.657 0.343 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.656 0.344 0.000
H43 Disorders of vitreous body
0.656 0.344 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.655 0.345 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.655 0.345 0.000
I62 Other nontraumatic intracranial haemorrhage
0.655 0.345 0.000
I22.8 Subsequent myocardial infarction of other sites
0.653 0.347 0.000
A04 Other bacterial intestinal infections
0.653 0.347 0.000
J37 Chronic laryngitis and laryngotracheitis
0.652 0.348 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.652 0.348 0.000
E83.8 Other disorders of mineral metabolism
0.652 0.348 0.000
E83.3 Disorders of phosphorus metabolism
0.652 0.348 0.000
E83.2 Disorders of zinc metabolism
0.652 0.348 0.000
E83.0 Disorders of copper metabolism
0.652 0.348 0.000
Z95.4 Presence of other heart-valve replacement
0.652 0.348 0.000
M20-M25 Other joint disorders
0.652 0.348 0.000
E11.3 With ophthalmic complications
0.651 0.349 0.000
H51 Other disorders of binocular movement
0.651 0.349 0.000
H49 Paralytic strabismus
0.651 0.349 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.651 0.349 0.000
J18 Pneumonia, organism unspecified
0.650 0.350 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.650 0.350 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.649 0.351 0.000
N60.1 Diffuse cystic mastopathy
0.649 0.351 0.000
E87.2 Acidosis
0.648 0.352 0.000
Z87 Personal history of other diseases and conditions
0.648 0.352 0.000
N39.3 Stress incontinence
0.647 0.353 0.000
Z47 Other orthopaedic follow-up care
0.646 0.354 0.000
Z89.6 Acquired absence of leg above knee
0.646 0.354 0.000
Z94.7 Corneal transplant status
0.646 0.354 0.000
N39.8 Other specified disorders of urinary system
0.645 0.355 0.000
E87.5 Hyperkalaemia
0.645 0.355 0.000
M06.9 Rheumatoid arthritis, unspecified
0.645 0.355 0.000
E11.5 With peripheral circulatory complications
0.644 0.356 0.000
M13.8 Other specified arthritis
0.642 0.358 0.000
M13.1 Monoarthritis, not elsewhere classified
0.642 0.358 0.000
M13.0 Polyarthritis, unspecified
0.642 0.358 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.642 0.358 0.000
Z45.3 Adjustment and management of implanted hearing device
0.642 0.358 0.000
Z45.1 Adjustment and management of infusion pump
0.642 0.358 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.641 0.359 0.000
I52 Other heart disorders in diseases classified elsewhere
0.641 0.359 0.000
I48 Atrial fibrillation and flutter
0.641 0.359 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.641 0.359 0.000
I41 Myocarditis in diseases classified elsewhere
0.641 0.359 0.000
I40 Acute myocarditis
0.641 0.359 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.641 0.359 0.000
I37 Pulmonary valve disorders
0.641 0.359 0.000
I36 Nonrheumatic tricuspid valve disorders
0.641 0.359 0.000
I32 Pericarditis in diseases classified elsewhere
0.641 0.359 0.000
I30 Acute pericarditis
0.641 0.359 0.000
E65-E68 Obesity and other hyperalimentation
0.640 0.360 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.639 0.361 0.000
I69.3 Sequelae of cerebral infarction
0.639 0.361 0.000
M17.5 Other secondary gonarthrosis
0.639 0.361 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.639 0.361 0.000
M17.3 Other posttraumatic gonarthrosis
0.639 0.361 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.639 0.361 0.000
H53.2 Diplopia
0.639 0.361 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.638 0.362 0.000
M80-M85 Disorders of bone density and structure
0.637 0.362 0.000
E87.7 Fluid overload
0.637 0.363 0.000
I61 Intracerebral haemorrhage
0.637 0.363 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.636 0.364 0.000
M06.0 Seronegative rheumatoid arthritis
0.636 0.364 0.000
R30-R39 Symptoms and signs involving the urinary system
0.636 0.364 0.000
N60.9 Benign mammary dysplasia, unspecified
0.635 0.365 0.000
N60.4 Mammary duct ectasia
0.635 0.365 0.000
M75 Shoulder lesions
0.635 0.365 0.000
J95-J99 Other diseases of the respiratory system
0.633 0.367 0.000
M47.1 Other spondylosis with myelopathy
0.633 0.367 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.633 0.367 0.000
I74.5 Embolism and thrombosis of iliac artery
0.633 0.367 0.000
Z96.7 Presence of other bone and tendon implants
0.631 0.369 0.000
D04 Carcinoma in situ of skin
0.631 0.369 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.631 0.369 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.630 0.369 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.630 0.369 0.000
H18 Other disorders of cornea
0.630 0.369 0.000
H17 Corneal scars and opacities
0.630 0.369 0.000
H15 Disorders of sclera
0.630 0.369 0.000
C43 Malignant melanoma of skin
0.630 0.370 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.629 0.371 0.000
I60 Subarachnoid haemorrhage
0.629 0.371 0.000
J36 Peritonsillar abscess
0.629 0.371 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.629 0.371 0.000
Z49.0 Preparatory care for dialysis
0.628 0.372 0.000
D64.8 Other specified anaemias
0.628 0.372 0.000
D64.4 Congenital dyserythropoietic anaemia
0.628 0.372 0.000
D64.3 Other sideroblastic anaemias
0.628 0.372 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.628 0.372 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.628 0.372 0.000
D64.0 Hereditary sideroblastic anaemia
0.628 0.372 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.626 0.374 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.626 0.374 0.000
N48 Other disorders of penis
0.626 0.374 0.000
Z98 Other postsurgical states
0.625 0.375 0.000
I77.1 Stricture of artery
0.625 0.375 0.000
D53 Other nutritional anaemias
0.624 0.376 0.000
D52 Folate deficiency anaemia
0.624 0.376 0.000
I51.9 Heart disease, unspecified
0.624 0.376 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.624 0.376 0.000
Y35-Y36 Legal intervention and operations of war
0.624 0.376 0.000
Y10-Y34 Event of undetermined intent
0.624 0.376 0.000
Y00-Y09 Assault
0.624 0.376 0.000
X85-X99 Assault
0.624 0.376 0.000
X60-X84 Intentional self-harm
0.624 0.376 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.624 0.376 0.000
X50-X57 Overexertion, travel and privation
0.624 0.376 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.624 0.376 0.000
X30-X39 Exposure to forces of nature
0.624 0.376 0.000
X20-X29 Contact with venomous animals and plants
0.624 0.376 0.000
X10-X19 Contact with heat and hot substances
0.624 0.376 0.000
X00-X09 Exposure to smoke, fire and flames
0.624 0.376 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.624 0.376 0.000
W75-W84 Other accidental threats to breathing
0.624 0.376 0.000
W65-W74 Accidental drowning and submersion
0.624 0.376 0.000
W50-W64 Exposure to animate mechanical forces
0.624 0.376 0.000
V98-V99 Other and unspecified transport accidents
0.624 0.376 0.000
V95-V97 Air and space transport accidents
0.624 0.376 0.000
V90-V94 Water transport accidents
0.624 0.376 0.000
V80-V89 Other land transport accidents
0.624 0.376 0.000
V70-V79 Bus occupant injured in transport accident
0.624 0.376 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.624 0.376 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.624 0.376 0.000
V40-V49 Car occupant injured in transport accident
0.624 0.376 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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