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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113797007
log Bayes Factor = 25.0423
Chromosome 16   position 12,649,840  (GRCh37) Explore rs113797007 on Ensembl!
Variant rs113797007 is part of Cluster X0213

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
E11.9 Without complications
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
S00-S09 Injuries to the head
0.993 0.007 0.000
I50 Heart failure
0.992 0.008 0.000
Chapter XIV Diseases of the genitourinary system
0.991 0.009 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.990 0.010 0.000
I20-I25 Ischaemic heart diseases
0.990 0.010 0.000
N17-N19 Renal failure
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
N18 Chronic renal failure
0.985 0.015 0.000
I50.9 Heart failure, unspecified
0.982 0.018 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.981 0.019 0.000
N18.3 Chronic kidney disease, stage 3
0.978 0.022 0.000
R10 Abdominal and pelvic pain
0.972 0.028 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.971 0.029 0.000
I60-I69 Cerebrovascular diseases
0.971 0.029 0.000
M06 Other rheumatoid arthritis
0.967 0.033 0.000
S02 Fracture of skull and facial bones
0.965 0.035 0.000
M50-M54 Other dorsopathies
0.964 0.036 0.000
I21 Acute myocardial infarction
0.960 0.040 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.958 0.042 0.000
M75 Shoulder lesions
0.957 0.043 0.000
M06.9 Rheumatoid arthritis, unspecified
0.956 0.044 0.000
M79.8 Other specified soft tissue disorders
0.953 0.047 0.000
I24 Other acute ischaemic heart diseases
0.952 0.048 0.000
G40-G47 Episodic and paroxysmal disorders
0.950 0.050 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.950 0.050 0.000
N18.9 Chronic renal failure, unspecified
0.948 0.052 0.000
S80-S89 Injuries to the knee and lower leg
0.947 0.053 0.000
Chapter VII Diseases of the eye and adnexa
0.946 0.054 0.000
I21.9 Acute myocardial infarction, unspecified
0.944 0.056 0.000
E11.4 With neurological complications
0.944 0.056 0.000
J90-J94 Other diseases of pleura
0.941 0.059 0.000
M54 Dorsalgia
0.940 0.060 0.000
J20-J22 Other acute lower respiratory infections
0.937 0.063 0.000
R11 Nausea and vomiting
0.934 0.066 0.000
M75.4 Impingement syndrome of shoulder
0.933 0.067 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.932 0.068 0.000
R10.1 Pain localised to upper abdomen
0.932 0.068 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.931 0.069 0.000
M54.5 Low back pain
0.927 0.073 0.000
R04 Haemorrhage from respiratory passages
0.926 0.074 0.000
S90-S99 Injuries to the ankle and foot
0.925 0.075 0.000
I24.8 Other forms of acute ischaemic heart disease
0.924 0.076 0.000
E20-E35 Disorders of other endocrine glands
0.924 0.076 0.000
S06 Intracranial injury
0.920 0.080 0.000
M80-M85 Disorders of bone density and structure
0.916 0.084 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.916 0.084 0.000
J30-J39 Other diseases of upper respiratory tract
0.915 0.085 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.911 0.089 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.909 0.091 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.907 0.093 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.907 0.093 0.000
R10.3 Pain localised to other parts of lower abdomen
0.906 0.094 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.903 0.097 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.903 0.097 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.899 0.101 0.000
I69 Sequelae of cerebrovascular disease
0.895 0.105 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.894 0.106 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.890 0.110 0.000
I05-I09 Chronic rheumatic heart diseases
0.890 0.110 0.000
R17 Unspecified jaundice
0.889 0.111 0.000
R04.0 Epistaxis
0.884 0.116 0.000
I31 Other diseases of pericardium
0.882 0.118 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.878 0.122 0.000
J22 Unspecified acute lower respiratory infection
0.878 0.122 0.000
I51 Complications and ill-defined descriptions of heart disease
0.877 0.123 0.000
S80 Superficial injury of lower leg
0.874 0.126 0.000
N30-N39 Other diseases of urinary system
0.873 0.127 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.872 0.128 0.000
Chapter XI Diseases of the digestive system
0.870 0.130 0.000
S00 Superficial injury of head
0.870 0.130 0.000
M54.56 Low back pain (Lumbar region)
0.869 0.131 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.868 0.132 0.000
S40-S49 Injuries to the shoulder and upper arm
0.868 0.132 0.000
K70-K77 Diseases of liver
0.866 0.134 0.000
Chapter V Mental and behavioural disorders
0.862 0.138 0.000
J09-J18 Influenza and pneumonia
0.861 0.139 0.000
M45-M49 Spondylopathies
0.860 0.140 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.860 0.140 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.859 0.141 0.000
R18 Ascites
0.857 0.143 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.857 0.143 0.000
M79.0 Rheumatism, unspecified
0.856 0.144 0.000
S92 Fracture of foot, except ankle
0.855 0.145 0.000
I65.2 Occlusion and stenosis of carotid artery
0.854 0.146 0.000
J92 Pleural plaque
0.853 0.147 0.000
M54.59 Low back pain (Site unspecified)
0.852 0.148 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.852 0.148 0.000
I45 Other conduction disorders
0.847 0.153 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.846 0.154 0.000
I22 Subsequent myocardial infarction
0.846 0.154 0.000
S02.1 Fracture of base of skull
0.845 0.155 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.844 0.156 0.000
E10 Insulin-dependent diabetes mellitus
0.844 0.156 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.843 0.157 0.000
I50.1 Left ventricular failure
0.842 0.158 0.000
Chapter I Certain infectious and parasitic diseases
0.841 0.159 0.000
K81 Cholecystitis
0.840 0.160 0.000
N20-N23 Urolithiasis
0.840 0.160 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.838 0.162 0.000
G47 Sleep disorders
0.837 0.163 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.834 0.166 0.000
J84 Other interstitial pulmonary diseases
0.834 0.166 0.000
N99-N99 Other disorders of the genitourinary system
0.832 0.168 0.000
I73 Other peripheral vascular diseases
0.832 0.168 0.000
R94 Abnormal results of function studies
0.832 0.168 0.000
M10 Gout
0.830 0.170 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
I74 Arterial embolism and thrombosis
0.828 0.172 0.000
E00-E07 Disorders of thyroid gland
0.826 0.174 0.000
K76 Other diseases of liver
0.825 0.175 0.000
G43 Migraine
0.824 0.176 0.000
D80-D89 Certain disorders involving the immune mechanism
0.824 0.176 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.823 0.177 0.000
J00-J06 Acute upper respiratory infections
0.814 0.186 0.000
E29 Testicular dysfunction
0.814 0.186 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.813 0.187 0.000
S02.3 Fracture of orbital floor
0.813 0.187 0.000
R05 Cough
0.812 0.188 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.811 0.189 0.000
K81.1 Chronic cholecystitis
0.810 0.190 0.000
I42 Cardiomyopathy
0.809 0.191 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.808 0.192 0.000
I77 Other disorders of arteries and arterioles
0.807 0.193 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.806 0.194 0.000
F30-F39 Mood [affective] disorders
0.805 0.195 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.803 0.197 0.000
I51.8 Other ill-defined heart diseases
0.803 0.197 0.000
H52 Disorders of refraction and accommodation
0.802 0.198 0.000
I63 Cerebral infarction
0.801 0.199 0.000
M81 Osteoporosis without pathological fracture
0.801 0.199 0.000
J60-J70 Lung diseases due to external agents
0.799 0.201 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.798 0.202 0.000
M77 Other enthesopathies
0.797 0.203 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.795 0.205 0.000
Y83.8 Other surgical procedures
0.795 0.205 0.000
G90-G99 Other disorders of the nervous system
0.795 0.205 0.000
J90 Pleural effusion, not elsewhere classified
0.795 0.205 0.000
Q60-Q64 Congenital malformations of the urinary system
0.794 0.206 0.000
W20-W49 Exposure to inanimate mechanical forces
0.794 0.206 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.793 0.207 0.000
N35 Urethral stricture
0.793 0.207 0.000
I31.9 Disease of pericardium, unspecified
0.793 0.207 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.792 0.208 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.791 0.209 0.000
K70 Alcoholic liver disease
0.790 0.210 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.790 0.210 0.000
E11.3 With ophthalmic complications
0.790 0.210 0.000
E11.6 With other specified complications
0.789 0.210 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.789 0.211 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.788 0.211 0.000
N25-N29 Other disorders of kidney and ureter
0.788 0.212 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.788 0.212 0.000
Y84.8 Other medical procedures
0.788 0.212 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.787 0.213 0.000
S82 Fracture of lower leg, including ankle
0.786 0.214 0.000
J95-J99 Other diseases of the respiratory system
0.786 0.214 0.000
I46 Cardiac arrest
0.786 0.214 0.000
I08 Multiple valve diseases
0.782 0.218 0.000
N23 Unspecified renal colic
0.782 0.218 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.782 0.218 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.780 0.219 0.000
R94.5 Abnormal results of liver function studies
0.780 0.220 0.000
I37 Pulmonary valve disorders
0.779 0.221 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.777 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.777 0.223 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.776 0.224 0.000
I95 Hypotension
0.775 0.225 0.000
S02.6 Fracture of mandible
0.775 0.225 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.773 0.226 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.773 0.227 0.000
M86-M90 Other osteopathies
0.772 0.228 0.000
H10-H13 Disorders of conjunctiva
0.771 0.229 0.000
M75.0 Adhesive capsulitis of shoulder
0.771 0.229 0.000
V40-V49 Car occupant injured in transport accident
0.770 0.230 0.000
R01 Cardiac murmurs and other cardiac sounds
0.770 0.230 0.000
S92.3 Fracture of metatarsal bone
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.768 0.232 0.000
G45.4 Transient global amnesia
0.767 0.233 0.000
R10.2 Pelvic and perineal pain
0.767 0.233 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.766 0.234 0.000
J18 Pneumonia, organism unspecified
0.766 0.234 0.000
I50.0 Congestive heart failure
0.765 0.235 0.000
D86 Sarcoidosis
0.765 0.235 0.000
N36 Other disorders of urethra
0.765 0.235 0.000
Q50-Q56 Congenital malformations of genital organs
0.765 0.235 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.762 0.237 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.761 0.239 0.000
F32 Depressive episode
0.761 0.239 0.000
I73.9 Peripheral vascular disease, unspecified
0.761 0.239 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.760 0.240 0.000
S02.10 Fracture of base of skull (closed)
0.760 0.240 0.000
I36 Nonrheumatic tricuspid valve disorders
0.759 0.241 0.000
G63.2 Diabetic polyneuropathy
0.758 0.242 0.000
I45.1 Other and unspecified right bundle-branch block
0.758 0.242 0.000
S00.0 Superficial injury of scalp
0.757 0.243 0.000
J94 Other pleural conditions
0.757 0.243 0.000
H52.1 Myopia
0.756 0.244 0.000
S02.4 Fracture of malar and maxillary bones
0.755 0.245 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.755 0.245 0.000
E50-E64 Other nutritional deficiencies
0.754 0.246 0.000
G43.9 Migraine, unspecified
0.754 0.246 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.753 0.247 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.752 0.248 0.000
J92.0 Pleural plaque with presence of asbestos
0.751 0.248 0.000
J38.3 Other diseases of vocal cords
0.751 0.249 0.000
G47.3 Sleep apnoea
0.751 0.249 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.750 0.250 0.000
S02.2 Fracture of nasal bones
0.750 0.250 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.749 0.251 0.000
E11.2 With renal complications
0.748 0.252 0.000
E13 Other specified diabetes mellitus
0.748 0.252 0.000
K76.8 Other specified diseases of liver
0.748 0.252 0.000
S02.0 Fracture of vault of skull
0.747 0.253 0.000
M91-M94 Chondropathies
0.746 0.254 0.000
Q80-Q89 Other congenital malformations
0.745 0.255 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.744 0.256 0.000
H30-H36 Disorders of choroid and retina
0.744 0.256 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.744 0.256 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.743 0.257 0.000
K83 Other diseases of biliary tract
0.743 0.257 0.000
D50-D53 Nutritional anaemias
0.741 0.259 0.000
A30-A49 Other bacterial diseases
0.740 0.260 0.000
K72 Hepatic failure, not elsewhere classified
0.740 0.260 0.000
J30 Vasomotor and allergic rhinitis
0.740 0.260 0.000
R12 Heartburn
0.739 0.261 0.000
S05 Injury of eye and orbit
0.739 0.261 0.000
S06.5 Traumatic subdural haemorrhage
0.738 0.262 0.000
J36 Peritonsillar abscess
0.737 0.263 0.000
I51.0 Cardiac septal defect, acquired
0.737 0.263 0.000
N35.9 Urethral stricture, unspecified
0.736 0.264 0.000
J20 Acute bronchitis
0.735 0.265 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.735 0.265 0.000
E29.1 Testicular hypofunction
0.735 0.265 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.734 0.265 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.734 0.266 0.000
M79.1 Myalgia
0.734 0.266 0.000
Y83.3 Surgical operation with formation of external stoma
0.733 0.267 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.733 0.267 0.000
G51 Facial nerve disorders
0.732 0.268 0.000
G20-G26 Extrapyramidal and movement disorders
0.732 0.268 0.000
M54.9 Dorsalgia, unspecified
0.732 0.268 0.000
S80.8 Other superficial injuries of lower leg
0.731 0.269 0.000
Y52 Agents primarily affecting the cardiovascular system
0.731 0.269 0.000
T66-T78 Other and unspecified effects of external causes
0.731 0.269 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.730 0.270 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.728 0.272 0.000
I60 Subarachnoid haemorrhage
0.727 0.273 0.000
M06.0 Seronegative rheumatoid arthritis
0.727 0.273 0.000
I07 Rheumatic tricuspid valve diseases
0.726 0.274 0.000
R04.2 Haemoptysis
0.726 0.274 0.000
E40-E46 Malnutrition
0.726 0.274 0.000
R16.1 Splenomegaly, not elsewhere classified
0.726 0.274 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.725 0.275 0.000
M84 Disorders of continuity of bone
0.725 0.275 0.000
I49 Other cardiac arrhythmias
0.725 0.275 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.724 0.276 0.000
M07 Psoriatic and enteropathic arthropathies
0.723 0.277 0.000
M10.9 Gout, unspecified
0.722 0.278 0.000
E16 Other disorders of pancreatic internal secretion
0.722 0.278 0.000
K86 Other diseases of pancreas
0.722 0.278 0.000
I63.9 Cerebral infarction, unspecified
0.722 0.278 0.000
M51 Other intervertebral disk disorders
0.722 0.278 0.000
M00-M03 Infectious arthropathies
0.721 0.279 0.000
Q00-Q07 Congenital malformations of the nervous system
0.720 0.280 0.000
S06.3 Focal brain injury
0.720 0.280 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.720 0.280 0.000
I70 Atherosclerosis
0.719 0.281 0.000
S06.2 Diffuse brain injury
0.719 0.281 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.719 0.281 0.000
N18.4 Chronic kidney disease, stage 4
0.718 0.282 0.000
N17 Acute renal failure
0.718 0.282 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.718 0.282 0.000
V20-V29 Motorcycle rider injured in transport accident
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
M81.9 Osteoporosis, unspecified
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.284 0.000
S06.4 Epidural haemorrhage
0.715 0.285 0.000
S02.8 Fractures of other skull and facial bones
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.285 0.000
J91 Pleural effusion in conditions classified elsewhere
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
Y44 Agents primarily affecting blood constituents
0.713 0.287 0.000
S92.0 Fracture of calcaneus
0.713 0.287 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.713 0.287 0.000
S08 Traumatic amputation of part of head
0.712 0.288 0.000
S07 Crushing injury of head
0.712 0.288 0.000
S04 Injury of cranial nerves
0.712 0.288 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.712 0.288 0.000
S80.9 Superficial injury of lower leg, unspecified
0.712 0.288 0.000
S06.0 Concussion
0.711 0.289 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.711 0.289 0.000
J18.1 Lobar pneumonia, unspecified
0.711 0.289 0.000
S99 Other and unspecified injuries of ankle and foot
0.710 0.290 0.000
I23 Certain current complications following acute myocardial infarction
0.710 0.290 0.000
E11.5 With peripheral circulatory complications
0.710 0.290 0.000
S00.8 Superficial injury of other parts of head
0.709 0.291 0.000
S20-S29 Injuries to the thorax
0.709 0.291 0.000
E70-E90 Metabolic disorders
0.709 0.291 0.000
K81.0 Acute cholecystitis
0.709 0.291 0.000
F32.9 Depressive episode, unspecified
0.709 0.291 0.000
N00-N08 Glomerular diseases
0.709 0.291 0.000
S82.0 Fracture of patella
0.709 0.291 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
J80 Adult respiratory distress syndrome
0.708 0.292 0.000
S40 Superficial injury of shoulder and upper arm
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
N10-N16 Renal tubulo-interstitial diseases
0.707 0.293 0.000
M05 Seropositive rheumatoid arthritis
0.707 0.293 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
S92.30 Fracture of metatarsal bone (closed)
0.707 0.293 0.000
N18.8 Other chronic renal failure
0.706 0.293 0.000
N18.1 Chronic kidney disease, stage 1
0.706 0.293 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.706 0.294 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.706 0.294 0.000
M79.6 Pain in limb
0.705 0.295 0.000
G44 Other headache syndromes
0.705 0.295 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.705 0.295 0.000
D86.9 Sarcoidosis, unspecified
0.704 0.296 0.000
I72 Other aneurysm
0.704 0.296 0.000
S02.30 Fracture of orbital floor (closed)
0.704 0.296 0.000
G70-G73 Diseases of myoneural junction and muscle
0.704 0.296 0.000
M14 Arthropathies in other diseases classified elsewhere
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.703 0.297 0.000
M79.9 Soft tissue disorder, unspecified
0.703 0.297 0.000
M79.5 Residual foreign body in soft tissue
0.703 0.297 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.703 0.297 0.000
M79.3 Panniculitis, unspecified
0.703 0.297 0.000
M79.2 Neuralgia and neuritis, unspecified
0.703 0.297 0.000
M80 Osteoporosis with pathological fracture
0.703 0.297 0.000
M71 Other bursopathies
0.703 0.297 0.000
J92.9 Pleural plaque without asbestos
0.702 0.298 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.702 0.298 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.701 0.299 0.000
N34 Urethritis and urethral syndrome
0.701 0.299 0.000
E23 Hypofunction and other disorders of pituitary gland
0.700 0.299 0.000
M75.2 Bicipital tendinitis
0.700 0.300 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.700 0.300 0.000
M75.1 Rotator cuff syndrome
0.700 0.300 0.000
M47 Spondylosis
0.700 0.300 0.000
M75.3 Calcific tendinitis of shoulder
0.699 0.301 0.000
I61 Intracerebral haemorrhage
0.699 0.301 0.000
J38.6 Stenosis of larynx
0.699 0.301 0.000
S60-S69 Injuries to the wrist and hand
0.698 0.302 0.000
J38.0 Paralysis of vocal cords and larynx
0.698 0.302 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.696 0.304 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.304 0.000
N18.2 Chronic kidney disease, stage 2
0.696 0.304 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.696 0.304 0.000
H40-H42 Glaucoma
0.695 0.305 0.000
M54.57 Low back pain (Lumbosacral region)
0.695 0.305 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
Y57 Other and unspecified drugs and medicaments
0.694 0.306 0.000
M06.8 Other specified rheumatoid arthritis
0.693 0.307 0.000
M06.4 Inflammatory polyarthropathy
0.693 0.307 0.000
M06.3 Rheumatoid nodule
0.693 0.307 0.000
M06.2 Rheumatoid bursitis
0.693 0.307 0.000
M06.1 Adult-onset Still's disease
0.693 0.307 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.692 0.308 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.692 0.308 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.692 0.308 0.000
S02.7 Multiple fractures involving skull and facial bones
0.692 0.308 0.000
S02.5 Fracture of tooth
0.692 0.308 0.000
V10-V19 Pedal cyclist injured in transport accident
0.691 0.309 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
M85 Other disorders of bone density and structure
0.690 0.310 0.000
M54.4 Lumbago with sciatica
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.689 0.311 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.688 0.311 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.688 0.311 0.000
B35-B49 Mycoses
0.688 0.311 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.688 0.312 0.000
I38 Endocarditis, valve unspecified
0.688 0.312 0.000
N19 Unspecified renal failure
0.688 0.312 0.000
T88.4 Failed or difficult intubation
0.688 0.312 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.687 0.312 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.687 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.313 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.313 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.313 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.687 0.313 0.000
R02 Gangrene, not elsewhere classified
0.686 0.314 0.000
M72 Fibroblastic disorders
0.686 0.314 0.000
M75.8 Other shoulder lesions
0.686 0.314 0.000
M75.9 Shoulder lesion, unspecified
0.686 0.314 0.000
H46 Optic neuritis
0.686 0.314 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.685 0.315 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.685 0.315 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.685 0.315 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.685 0.315 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.685 0.315 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.685 0.315 0.000
Y84.0 Cardiac catheterisation
0.685 0.315 0.000
M79.88 Other specified soft tissue disorders (Other)
0.683 0.317 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.683 0.317 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.683 0.317 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.683 0.317 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.683 0.317 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.683 0.317 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.683 0.317 0.000
I24.1 Dressler's syndrome
0.682 0.318 0.000
I08.0 Disorders of both mitral and aortic valves
0.682 0.318 0.000
I62 Other nontraumatic intracranial haemorrhage
0.682 0.318 0.000
M53 Other dorsopathies, not elsewhere classified
0.681 0.318 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.681 0.319 0.000
G41 Status epilepticus
0.681 0.319 0.000
K76.9 Liver disease, unspecified
0.681 0.319 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.681 0.319 0.000
G50 Disorders of trigeminal nerve
0.681 0.319 0.000
R14 Flatulence and related conditions
0.680 0.320 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.680 0.320 0.000
G56 Mononeuropathies of upper limb
0.680 0.320 0.000
F60-F69 Disorders of adult personality and behaviour
0.680 0.320 0.000
T18 Foreign body in alimentary tract
0.680 0.320 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.679 0.320 0.000
M11 Other crystal arthropathies
0.679 0.321 0.000
S88 Traumatic amputation of lower leg
0.679 0.321 0.000
S87 Crushing injury of lower leg
0.679 0.321 0.000
S86 Injury of muscle and tendon at lower leg level
0.679 0.321 0.000
S85 Injury of blood vessels at lower leg level
0.679 0.321 0.000
S84 Injury of nerves at lower leg level
0.679 0.321 0.000
K74 Fibrosis and cirrhosis of liver
0.679 0.321 0.000
S90 Superficial injury of ankle and foot
0.679 0.321 0.000
Q61 Cystic kidney disease
0.677 0.323 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.677 0.323 0.000
H43-H45 Disorders of vitreous body and globe
0.676 0.324 0.000
J39 Other diseases of upper respiratory tract
0.676 0.324 0.000
T91 Sequelae of injuries of neck and trunk
0.675 0.324 0.000
G59.0 Diabetic mononeuropathy
0.675 0.325 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.675 0.325 0.000
I95.1 Orthostatic hypotension
0.675 0.325 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.675 0.325 0.000
W00-W19 Falls
0.674 0.325 0.000
M54.8 Other dorsalgia
0.674 0.326 0.000
M54.6 Pain in thoracic spine
0.674 0.326 0.000
M54.0 Panniculitis affecting regions of neck and back
0.674 0.326 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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