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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114080907
log Bayes Factor = 15.1857
Chromosome 1   position 21,077,245  (GRCh37) Explore rs114080907 on Ensembl!
Variant rs114080907 is part of Cluster X0003

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
Z92 Personal history of medical treatment
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.996 0.004 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.993 0.007 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
Z95.1 Presence of aortocoronary bypass graft
0.991 0.009 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.987 0.013 0.000
Chapter XIV Diseases of the genitourinary system
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.984 0.016 0.000
K80 Cholelithiasis
0.982 0.018 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.979 0.021 0.000
K70-K77 Diseases of liver
0.977 0.023 0.000
N30-N39 Other diseases of urinary system
0.975 0.025 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.974 0.026 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.973 0.027 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.972 0.028 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.970 0.030 0.000
K70 Alcoholic liver disease
0.965 0.035 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.964 0.036 0.000
N20-N23 Urolithiasis
0.954 0.046 0.000
K82 Other diseases of gallbladder
0.951 0.049 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.949 0.051 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.948 0.052 0.000
Z93 Artificial opening status
0.941 0.059 0.000
I05-I09 Chronic rheumatic heart diseases
0.940 0.060 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.934 0.066 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.934 0.066 0.000
Chapter I Certain infectious and parasitic diseases
0.933 0.067 0.000
N23 Unspecified renal colic
0.931 0.069 0.000
Z87 Personal history of other diseases and conditions
0.931 0.069 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.931 0.069 0.000
Chapter XXII Codes for special purposes
0.927 0.073 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.925 0.075 0.000
I71 Aortic aneurysm and dissection
0.921 0.079 0.000
I51 Complications and ill-defined descriptions of heart disease
0.920 0.080 0.000
K90-K93 Other diseases of the digestive system
0.920 0.080 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.919 0.081 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.916 0.084 0.000
M50-M54 Other dorsopathies
0.911 0.089 0.000
Z45 Adjustment and management of implanted device
0.911 0.089 0.000
D10-D36 Benign neoplasms
0.907 0.093 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.905 0.095 0.000
M70-M79 Other soft tissue disorders
0.903 0.097 0.000
N35 Urethral stricture
0.901 0.099 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.900 0.100 0.000
K70.9 Alcoholic liver disease, unspecified
0.899 0.101 0.000
N30 Cystitis
0.898 0.102 0.000
Z45.2 Adjustment and management of vascular access device
0.896 0.104 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.894 0.106 0.000
I49 Other cardiac arrhythmias
0.894 0.106 0.000
B35-B49 Mycoses
0.894 0.106 0.000
E70-E90 Metabolic disorders
0.893 0.107 0.000
Z97 Presence of other devices
0.893 0.107 0.000
K70.3 Alcoholic cirrhosis of liver
0.888 0.112 0.000
I51.7 Cardiomegaly
0.887 0.113 0.000
M05-M14 Inflammatory polyarthropathies
0.887 0.113 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.885 0.115 0.000
M51 Other intervertebral disk disorders
0.882 0.118 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.879 0.121 0.000
Z35 Supervision of high-risk pregnancy
0.878 0.122 0.000
I07 Rheumatic tricuspid valve diseases
0.874 0.126 0.000
D25 Leiomyoma of uterus
0.870 0.130 0.000
I73 Other peripheral vascular diseases
0.870 0.130 0.000
M10 Gout
0.868 0.132 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.862 0.138 0.000
I70 Atherosclerosis
0.862 0.138 0.000
I20-I25 Ischaemic heart diseases
0.861 0.139 0.000
D23 Other benign neoplasms of skin
0.859 0.141 0.000
B37 Candidiasis
0.859 0.141 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.857 0.143 0.000
I47 Paroxysmal tachycardia
0.856 0.144 0.000
M10.9 Gout, unspecified
0.854 0.146 0.000
N35.9 Urethral stricture, unspecified
0.848 0.152 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.847 0.153 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.844 0.156 0.000
I60-I69 Cerebrovascular diseases
0.843 0.157 0.000
E83 Disorders of mineral metabolism
0.842 0.158 0.000
Chapter VIII Diseases of the ear and mastoid process
0.842 0.158 0.000
D25.9 Leiomyoma of uterus, unspecified
0.841 0.159 0.000
Z40 Prophylactic surgery
0.840 0.160 0.000
Z95.0 Presence of cardiac pacemaker
0.839 0.161 0.000
N32 Other disorders of bladder
0.839 0.161 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.838 0.162 0.000
Z93.1 Gastrostomy status
0.838 0.162 0.000
K86 Other diseases of pancreas
0.837 0.163 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.836 0.164 0.000
I50 Heart failure
0.834 0.166 0.000
M10.99 Gout, unspecified (Site unspecified)
0.833 0.167 0.000
Z46 Fitting and adjustment of other devices
0.832 0.168 0.000
N30.9 Cystitis, unspecified
0.832 0.168 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.832 0.168 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.830 0.170 0.000
I72 Other aneurysm
0.828 0.172 0.000
Z35.5 Supervision of elderly primigravida
0.827 0.173 0.000
I07.1 Tricuspid insufficiency
0.826 0.174 0.000
Z85 Personal history of malignant neoplasm
0.825 0.175 0.000
I82 Other venous embolism and thrombosis
0.825 0.175 0.000
E50-E64 Other nutritional deficiencies
0.824 0.176 0.000
Z93.3 Colostomy status
0.822 0.178 0.000
I35 Nonrheumatic aortic valve disorders
0.821 0.179 0.000
K70.4 Alcoholic hepatic failure
0.821 0.179 0.000
M51.2 Other specified intervertebral disk displacement
0.820 0.180 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.819 0.181 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.819 0.181 0.000
A30-A49 Other bacterial diseases
0.815 0.185 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.815 0.185 0.000
C15-C26 Malignant neoplasms of digestive organs
0.814 0.186 0.000
K82.9 Disease of gallbladder, unspecified
0.812 0.188 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.812 0.188 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.809 0.190 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.809 0.191 0.000
E20-E35 Disorders of other endocrine glands
0.808 0.192 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.807 0.193 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.807 0.193 0.000
Z94 Transplanted organ and tissue status
0.806 0.194 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.804 0.196 0.000
D46 Myelodysplastic syndromes
0.804 0.196 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.798 0.202 0.000
K72 Hepatic failure, not elsewhere classified
0.798 0.202 0.000
I24 Other acute ischaemic heart diseases
0.797 0.203 0.000
I49.8 Other specified cardiac arrhythmias
0.797 0.203 0.000
M79.6 Pain in limb
0.797 0.203 0.000
K82.8 Other specified diseases of gallbladder
0.796 0.204 0.000
I44 Atrioventricular and left bundle-branch block
0.795 0.205 0.000
I47.1 Supraventricular tachycardia
0.794 0.206 0.000
Z97.8 Presence of other specified devices
0.794 0.206 0.000
I50.9 Heart failure, unspecified
0.790 0.210 0.000
M91-M94 Chondropathies
0.790 0.210 0.000
E83.4 Disorders of magnesium metabolism
0.789 0.211 0.000
K82.4 Cholesterolosis of gallbladder
0.788 0.212 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.787 0.213 0.000
E86 Volume depletion
0.787 0.213 0.000
I05 Rheumatic mitral valve diseases
0.787 0.213 0.000
Q80-Q89 Other congenital malformations
0.787 0.213 0.000
D23.5 Skin of trunk
0.786 0.214 0.000
Z39 Postpartum care and examination
0.784 0.216 0.000
K85 Acute pancreatitis
0.782 0.218 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.782 0.218 0.000
Z31 Procreative management
0.782 0.218 0.000
K90 Intestinal malabsorption
0.781 0.219 0.000
I25 Chronic ischaemic heart disease
0.777 0.223 0.000
B37.0 Candidal stomatitis
0.777 0.223 0.000
Z46.6 Fitting and adjustment of urinary device
0.776 0.224 0.000
Z34 Supervision of normal pregnancy
0.775 0.225 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.775 0.225 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.774 0.226 0.000
S70-S79 Injuries to the hip and thigh
0.773 0.227 0.000
Z99.2 Dependence on renal dialysis
0.773 0.227 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.768 0.232 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.768 0.232 0.000
U80 Agent resistant to penicillin and related antibiotics
0.768 0.232 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.766 0.234 0.000
I74 Arterial embolism and thrombosis
0.766 0.234 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.766 0.234 0.000
Z49 Care involving dialysis
0.766 0.234 0.000
M79.0 Rheumatism, unspecified
0.766 0.234 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.765 0.235 0.000
D00-D09 In situ neoplasms
0.764 0.236 0.000
Z93.0 Tracheostomy status
0.763 0.237 0.000
Q60-Q64 Congenital malformations of the urinary system
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
I63 Cerebral infarction
0.762 0.238 0.000
C92 Myeloid leukaemia
0.758 0.241 0.000
I78 Diseases of capillaries
0.758 0.242 0.000
N17-N19 Renal failure
0.758 0.242 0.000
Z36 Antenatal screening
0.756 0.244 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.754 0.246 0.000
Z93.6 Other artificial openings of urinary tract status
0.754 0.246 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.753 0.247 0.000
E53 Deficiency of other B group vitamins
0.753 0.247 0.000
I85 Oesophageal varices
0.752 0.248 0.000
Z92.8 Personal history of other medical treatment
0.752 0.248 0.000
K83 Other diseases of biliary tract
0.750 0.250 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.749 0.251 0.000
N21 Calculus of lower urinary tract
0.749 0.251 0.000
N30.3 Trigonitis
0.748 0.252 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.748 0.252 0.000
Z81 Family history of mental and behavioural disorders
0.747 0.253 0.000
M79.66 Pain in limb (Lower leg)
0.747 0.253 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.746 0.254 0.000
D23.2 Skin of ear and external auricular canal
0.746 0.254 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.745 0.255 0.000
Z50 Care involving use of rehabilitation procedures
0.745 0.255 0.000
M71 Other bursopathies
0.745 0.255 0.000
Z92.0 Personal history of contraception
0.744 0.255 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.744 0.256 0.000
D24 Benign neoplasm of breast
0.743 0.257 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.743 0.257 0.000
M79.8 Other specified soft tissue disorders
0.743 0.257 0.000
K65-K67 Diseases of peritoneum
0.743 0.257 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.743 0.257 0.000
D47.2 Monoclonal gammopathy
0.742 0.258 0.000
I36 Nonrheumatic tricuspid valve disorders
0.742 0.258 0.000
I87 Other disorders of veins
0.742 0.258 0.000
C60-C63 Malignant neoplasms of male genital organs
0.741 0.259 0.000
Z95.4 Presence of other heart-valve replacement
0.740 0.260 0.000
N34 Urethritis and urethral syndrome
0.740 0.260 0.000
Z89 Acquired absence of limb
0.740 0.260 0.000
K82.2 Perforation of gallbladder
0.740 0.260 0.000
I73.0 Raynaud's syndrome
0.739 0.261 0.000
I82.8 Embolism and thrombosis of other specified veins
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.738 0.262 0.000
I49.5 Sick sinus syndrome
0.737 0.263 0.000
Z87.8 Personal history of other specified conditions
0.737 0.263 0.000
N32.0 Bladder-neck obstruction
0.736 0.264 0.000
N30.0 Acute cystitis
0.736 0.264 0.000
M65-M68 Disorders of synovium and tendon
0.735 0.265 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.734 0.266 0.000
S90-S99 Injuries to the ankle and foot
0.734 0.266 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.734 0.266 0.000
B37.4 Candidiasis of other urogenital sites
0.734 0.266 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.733 0.267 0.000
S10-S19 Injuries to the neck
0.732 0.268 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.732 0.268 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.731 0.269 0.000
K75 Other inflammatory liver diseases
0.730 0.270 0.000
I77 Other disorders of arteries and arterioles
0.730 0.270 0.000
I42 Cardiomyopathy
0.729 0.271 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.729 0.271 0.000
K40-K46 Hernia
0.729 0.271 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.728 0.272 0.000
T51 Toxic effect of alcohol
0.728 0.272 0.000
N60-N64 Disorders of breast
0.728 0.272 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.726 0.274 0.000
I82.2 Embolism and thrombosis of vena cava
0.725 0.275 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.725 0.275 0.000
N25-N29 Other disorders of kidney and ureter
0.725 0.275 0.000
N10-N16 Renal tubulo-interstitial diseases
0.725 0.275 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
D11 Benign neoplasm of major salivary glands
0.724 0.276 0.000
Chapter V Mental and behavioural disorders
0.724 0.276 0.000
I70.0 Atherosclerosis of aorta
0.724 0.276 0.000
K82.1 Hydrops of gallbladder
0.722 0.278 0.000
H80-H83 Diseases of inner ear
0.721 0.279 0.000
M51.9 Intervertebral disk disorder, unspecified
0.720 0.280 0.000
E83.3 Disorders of phosphorus metabolism
0.720 0.280 0.000
D23.3 Skin of other and unspecified parts of face
0.719 0.281 0.000
D10 Benign neoplasm of mouth and pharynx
0.719 0.281 0.000
M15-M19 Arthrosis
0.719 0.281 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.716 0.284 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
Chapter XX External causes of morbidity and mortality
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
I63.9 Cerebral infarction, unspecified
0.715 0.285 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.714 0.286 0.000
K91.4 Colostomy and enterostomy malfunction
0.714 0.286 0.000
I51.0 Cardiac septal defect, acquired
0.714 0.286 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.713 0.287 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.713 0.287 0.000
I51.6 Cardiovascular disease, unspecified
0.712 0.288 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.711 0.288 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.711 0.289 0.000
E85 Amyloidosis
0.711 0.289 0.000
I49.3 Ventricular premature depolarisation
0.711 0.289 0.000
I49.1 Atrial premature depolarisation
0.710 0.290 0.000
D45 Polycythaemia vera
0.710 0.290 0.000
Z32 Pregnancy examination and test
0.709 0.291 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.709 0.291 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.708 0.292 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.708 0.292 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.708 0.292 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.708 0.292 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.708 0.292 0.000
Z82.2 Family history of deafness and hearing loss
0.708 0.292 0.000
Z82.1 Family history of blindness and visual loss
0.708 0.292 0.000
M76 Enthesopathies of lower limb, excluding foot
0.708 0.292 0.000
M80-M85 Disorders of bone density and structure
0.707 0.293 0.000
K70.0 Alcoholic fatty liver
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.705 0.294 0.000
I48 Atrial fibrillation and flutter
0.705 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.705 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.705 0.294 0.000
I40 Acute myocarditis
0.705 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.705 0.294 0.000
I37 Pulmonary valve disorders
0.705 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.705 0.294 0.000
B35 Dermatophytosis
0.705 0.294 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.705 0.295 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.705 0.295 0.000
K80.3 Calculus of bile duct with cholangitis
0.704 0.296 0.000
M54 Dorsalgia
0.704 0.296 0.000
Z82.3 Family history of stroke
0.704 0.296 0.000
I73.9 Peripheral vascular disease, unspecified
0.703 0.297 0.000
M79.60 Pain in limb (Multiple sites)
0.702 0.298 0.000
M10.90 Gout, unspecified (Multiple sites)
0.701 0.299 0.000
E53.8 Deficiency of other specified B group vitamins
0.701 0.299 0.000
K77 Liver disorders in diseases classified elsewhere
0.701 0.299 0.000
K73 Chronic hepatitis, not elsewhere classified
0.701 0.299 0.000
K71 Toxic liver disease
0.701 0.299 0.000
Z33 Pregnant state, incidental
0.700 0.300 0.000
Z97.0 Presence of artificial eye
0.699 0.301 0.000
N37 Urethral disorders in diseases classified elsewhere
0.699 0.301 0.000
N33 Bladder disorders in diseases classified elsewhere
0.699 0.301 0.000
Chapter VI Diseases of the nervous system
0.699 0.301 0.000
Z83 Family history of other specific disorders
0.699 0.301 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.699 0.301 0.000
Z99.1 Dependence on respirator
0.699 0.301 0.000
D32 Benign neoplasm of meninges
0.699 0.301 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.698 0.301 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.698 0.301 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.698 0.301 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.698 0.301 0.000
I34 Nonrheumatic mitral valve disorders
0.698 0.302 0.000
I71.0 Dissection of aorta [any part]
0.698 0.302 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.698 0.302 0.000
T33-T35 Frostbite
0.697 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.697 0.303 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.697 0.303 0.000
T00-T07 Injuries involving multiple body regions
0.697 0.303 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.696 0.304 0.000
A80-A89 Viral infections of the central nervous system
0.696 0.304 0.000
D25.1 Intramural leiomyoma of uterus
0.696 0.304 0.000
C78.0 Secondary malignant neoplasm of lung
0.696 0.304 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.696 0.304 0.000
I25.1 Atherosclerotic heart disease
0.695 0.305 0.000
Z35.8 Supervision of other high-risk pregnancies
0.695 0.305 0.000
K74 Fibrosis and cirrhosis of liver
0.694 0.306 0.000
A49 Bacterial infection of unspecified site
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
C81 Hodgkin's disease
0.694 0.306 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
K86.8 Other specified diseases of pancreas
0.693 0.307 0.000
M79.7 Fibromyalgia
0.693 0.307 0.000
B37.9 Candidiasis, unspecified
0.693 0.307 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.691 0.308 0.000
D30 Benign neoplasm of urinary organs
0.691 0.309 0.000
I35.0 Aortic (valve) stenosis
0.691 0.309 0.000
K91.3 Postoperative intestinal obstruction
0.691 0.309 0.000
I33 Acute and subacute endocarditis
0.690 0.309 0.000
I60 Subarachnoid haemorrhage
0.690 0.310 0.000
D25.0 Submucous leiomyoma of uterus
0.689 0.311 0.000
N92 Excessive, frequent and irregular menstruation
0.689 0.311 0.000
N32.3 Diverticulum of bladder
0.689 0.311 0.000
I44.2 Atrioventricular block, complete
0.689 0.311 0.000
K86.9 Disease of pancreas, unspecified
0.688 0.312 0.000
M00-M03 Infectious arthropathies
0.688 0.312 0.000
K70.1 Alcoholic hepatitis
0.687 0.313 0.000
I44.3 Other and unspecified atrioventricular block
0.687 0.313 0.000
D48.6 Breast
0.686 0.314 0.000
E40-E46 Malnutrition
0.685 0.314 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.685 0.315 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.684 0.316 0.000
K82.3 Fistula of gallbladder
0.682 0.318 0.000
K82.0 Obstruction of gallbladder
0.682 0.318 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.682 0.318 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.682 0.318 0.000
Z94.2 Lung transplant status
0.682 0.318 0.000
K81 Cholecystitis
0.681 0.319 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.681 0.319 0.000
Z38 Liveborn infants according to place of birth
0.680 0.320 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.680 0.320 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.680 0.320 0.000
E83.1 Disorders of iron metabolism
0.679 0.321 0.000
I72.3 Aneurysm of iliac artery
0.679 0.321 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.679 0.321 0.000
H65-H75 Diseases of middle ear and mastoid
0.678 0.322 0.000
D18 Haemangioma and lymphangioma, any site
0.677 0.323 0.000
E73 Lactose intolerance
0.677 0.323 0.000
C77.2 Intra-abdominal lymph nodes
0.676 0.324 0.000
C26.0 Intestinal tract, part unspecified
0.675 0.325 0.000
Z93.9 Artificial opening status, unspecified
0.675 0.325 0.000
Z93.8 Other artificial opening status
0.675 0.325 0.000
D48.0 Bone and articular cartilage
0.674 0.326 0.000
I09 Other rheumatic heart diseases
0.674 0.326 0.000
I06 Rheumatic aortic valve diseases
0.674 0.326 0.000
N00-N08 Glomerular diseases
0.674 0.326 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.674 0.326 0.000
N32.9 Bladder disorder, unspecified
0.673 0.327 0.000
D38.1 Trachea, bronchus and lung
0.672 0.328 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.672 0.328 0.000
N60 Benign mammary dysplasia
0.672 0.328 0.000
Z95.2 Presence of prosthetic heart valve
0.672 0.328 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.671 0.329 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.671 0.329 0.000
Z44 Fitting and adjustment of external prosthetic device
0.670 0.330 0.000
Z40.8 Other prophylactic surgery
0.670 0.330 0.000
K72.9 Hepatic failure, unspecified
0.670 0.330 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.669 0.330 0.000
Q35-Q37 Cleft lip and cleft palate
0.669 0.330 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.669 0.330 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.669 0.330 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.331 0.000
B65-B83 Helminthiases
0.669 0.331 0.000
B50-B64 Protozoal diseases
0.669 0.331 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.669 0.331 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.331 0.000
A75-A79 Rickettsioses
0.669 0.331 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.331 0.000
A65-A69 Other spirochaetal diseases
0.669 0.331 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.331 0.000
A15-A19 Tuberculosis
0.669 0.331 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.669 0.331 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.668 0.332 0.000
I85.0 Oesophageal varices with bleeding
0.667 0.333 0.000
U80.1 Methicillin resistant agent
0.665 0.335 0.000
Z41 Procedures for purposes other than remedying health state
0.665 0.335 0.000
M18 Arthrosis of first carpometacarpal joint
0.664 0.336 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.663 0.337 0.000
I30 Acute pericarditis
0.662 0.338 0.000
C77.0 Lymph nodes of head, face and neck
0.662 0.338 0.000
Z97.4 Presence of external hearing-aid
0.661 0.339 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.661 0.339 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.661 0.339 0.000
M51.8 Other specified intervertebral disk disorders
0.660 0.339 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.660 0.340 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.660 0.340 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.660 0.340 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.660 0.340 0.000
E21.3 Hyperparathyroidism, unspecified
0.660 0.340 0.000
I51.5 Myocardial degeneration
0.660 0.340 0.000
I51.4 Myocarditis, unspecified
0.660 0.340 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.660 0.340 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.660 0.340 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.660 0.340 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.660 0.340 0.000
B37.8 Candidiasis of other sites
0.660 0.340 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.659 0.341 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.659 0.341 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.659 0.341 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.659 0.341 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.659 0.341 0.000
T36 Poisoning by systemic antibiotics
0.659 0.341 0.000
D04 Carcinoma in situ of skin
0.659 0.341 0.000
A41 Other septicaemia
0.657 0.343 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.657 0.343 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.657 0.343 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.657 0.343 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.657 0.343 0.000
M94 Other disorders of cartilage
0.656 0.343 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.656 0.344 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.656 0.344 0.000
K92 Other diseases of digestive system
0.655 0.345 0.000
Z39.2 Routine postpartum follow-up
0.654 0.346 0.000
M53 Other dorsopathies, not elsewhere classified
0.653 0.346 0.000
D39.1 Ovary
0.653 0.347 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.653 0.347 0.000
Z45.3 Adjustment and management of implanted hearing device
0.653 0.347 0.000
Z48 Other surgical follow-up care
0.653 0.347 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.653 0.347 0.000
C92.1 Chronic myeloid leukaemia
0.652 0.348 0.000
E88 Other metabolic disorders
0.652 0.348 0.000
Z54 Convalescence
0.652 0.348 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.651 0.349 0.000
B15-B19 Viral hepatitis
0.651 0.349 0.000
D31 Benign neoplasm of eye and adnexa
0.650 0.349 0.000
D29 Benign neoplasm of male genital organs
0.650 0.349 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.650 0.349 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.650 0.349 0.000
D19 Benign neoplasm of mesothelial tissue
0.650 0.349 0.000
D16 Benign neoplasm of bone and articular cartilage
0.650 0.349 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.650 0.349 0.000
D26 Other benign neoplasms of uterus
0.650 0.350 0.000
S60-S69 Injuries to the wrist and hand
0.649 0.351 0.000
Z52 Donors of organs and tissues
0.649 0.351 0.000
N30.1 Interstitial cystitis (chronic)
0.649 0.351 0.000
S00-S09 Injuries to the head
0.648 0.352 0.000
Z92.3 Personal history of irradiation
0.648 0.352 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.648 0.352 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.647 0.353 0.000
C09 Malignant neoplasm of tonsil
0.647 0.353 0.000
N35.8 Other urethral stricture
0.646 0.354 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.646 0.354 0.000
N35.0 Posttraumatic urethral stricture
0.646 0.354 0.000
S32 Fracture of lumbar spine and pelvis
0.646 0.354 0.000
U89 Agent resistant to other and unspecified antibiotics
0.646 0.354 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.646 0.354 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.645 0.355 0.000
M40-M43 Deforming dorsopathies
0.645 0.355 0.000
T42.4 Benzodiazepines
0.645 0.355 0.000
I87.1 Compression of vein
0.644 0.356 0.000
N30.4 Irradiation cystitis
0.644 0.356 0.000
C15 Malignant neoplasm of oesophagus
0.644 0.356 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.644 0.356 0.000
C80 Malignant neoplasm without specification of site
0.643 0.357 0.000
I08 Multiple valve diseases
0.642 0.358 0.000
Z31.2 In vitro fertilisation
0.642 0.358 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.641 0.359 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.641 0.359 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.641 0.359 0.000
D47.4 Osteomyelofibrosis
0.641 0.359 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.641 0.359 0.000
I49.2 Junctional premature depolarisation
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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