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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114144436
log Bayes Factor = 12.5218
Chromosome 17   position 2,832,984  (GRCh37) Explore rs114144436 on Ensembl!
Variant rs114144436 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
F32 Depressive episode
0.993 0.007 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
F32.9 Depressive episode, unspecified
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
E10 Insulin-dependent diabetes mellitus
0.982 0.018 0.000
H30-H36 Disorders of choroid and retina
0.979 0.021 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.972 0.028 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.956 0.044 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.954 0.046 0.000
S20-S29 Injuries to the thorax
0.949 0.051 0.000
Chapter VIII Diseases of the ear and mastoid process
0.948 0.052 0.000
H35 Other retinal disorders
0.943 0.057 0.000
E11.3 With ophthalmic complications
0.937 0.063 0.000
H36 Retinal disorders in diseases classified elsewhere
0.936 0.064 0.000
F31 Bipolar affective disorder
0.935 0.065 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.932 0.068 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.928 0.072 0.000
E10.9 Without complications
0.926 0.074 0.000
H25-H28 Disorders of lens
0.924 0.076 0.000
G62 Other polyneuropathies
0.923 0.077 0.000
E14 Unspecified diabetes mellitus
0.922 0.078 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.920 0.080 0.000
E65-E68 Obesity and other hyperalimentation
0.917 0.083 0.000
M15-M19 Arthrosis
0.914 0.086 0.000
E20-E35 Disorders of other endocrine glands
0.910 0.090 0.000
E10.3 With ophthalmic complications
0.909 0.091 0.000
H36.0 Diabetic retinopathy
0.906 0.094 0.000
H35.3 Degeneration of macula and posterior pole
0.905 0.095 0.000
H65-H75 Diseases of middle ear and mastoid
0.899 0.101 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.894 0.106 0.000
S00-S09 Injuries to the head
0.893 0.107 0.000
G62.9 Polyneuropathy, unspecified
0.890 0.110 0.000
G90-G99 Other disorders of the nervous system
0.886 0.114 0.000
H26 Other cataract
0.886 0.114 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.882 0.117 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.880 0.120 0.000
E11.9 Without complications
0.879 0.121 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.879 0.121 0.000
Chapter II Neoplasms
0.878 0.122 0.000
H53-H54 Visual disturbances and blindness
0.875 0.125 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.871 0.129 0.000
M86-M90 Other osteopathies
0.870 0.130 0.000
F31.9 Bipolar affective disorder, unspecified
0.866 0.134 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.863 0.137 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.862 0.138 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.858 0.142 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.858 0.142 0.000
S40-S49 Injuries to the shoulder and upper arm
0.855 0.145 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.853 0.147 0.000
Chapter I Certain infectious and parasitic diseases
0.851 0.149 0.000
T43.2 Other and unspecified antidepressants
0.851 0.149 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.850 0.150 0.000
Chapter XX External causes of morbidity and mortality
0.850 0.150 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.848 0.152 0.000
M16 Coxarthrosis [arthrosis of hip]
0.844 0.156 0.000
C34 Malignant neoplasm of bronchus and lung
0.843 0.157 0.000
E13 Other specified diabetes mellitus
0.843 0.157 0.000
H26.9 Cataract, unspecified
0.843 0.157 0.000
T39.1 4-Aminophenol derivatives
0.843 0.157 0.000
E14.9 Without complications
0.837 0.163 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.834 0.166 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.834 0.166 0.000
E11.0 With coma
0.832 0.168 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.829 0.171 0.000
H72 Perforation of tympanic membrane
0.828 0.172 0.000
M18 Arthrosis of first carpometacarpal joint
0.826 0.173 0.000
S27 Injury of other and unspecified intrathoracic organs
0.825 0.175 0.000
H55-H59 Other disorders of eye and adnexa
0.822 0.178 0.000
E66 Obesity
0.819 0.181 0.000
S01 Open wound of head
0.819 0.181 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.818 0.182 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.818 0.182 0.000
C79 Secondary malignant neoplasm of other sites
0.817 0.183 0.000
M80-M85 Disorders of bone density and structure
0.813 0.187 0.000
M16.9 Coxarthrosis, unspecified
0.807 0.193 0.000
G40-G47 Episodic and paroxysmal disorders
0.803 0.197 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.802 0.198 0.000
C34.3 Lower lobe, bronchus or lung
0.802 0.198 0.000
H54 Blindness and low vision
0.801 0.199 0.000
E11.5 With peripheral circulatory complications
0.801 0.199 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.800 0.200 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.800 0.200 0.000
B35-B49 Mycoses
0.797 0.203 0.000
S80-S89 Injuries to the knee and lower leg
0.796 0.204 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.792 0.208 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.788 0.212 0.000
E11.2 With renal complications
0.788 0.212 0.000
F30 Manic episode
0.786 0.214 0.000
H02 Other disorders of eyelid
0.784 0.216 0.000
H10-H13 Disorders of conjunctiva
0.780 0.220 0.000
Q21 Congenital malformations of cardiac septa
0.779 0.221 0.000
G70-G73 Diseases of myoneural junction and muscle
0.776 0.224 0.000
F60-F69 Disorders of adult personality and behaviour
0.776 0.224 0.000
S10-S19 Injuries to the neck
0.774 0.226 0.000
M91-M94 Chondropathies
0.773 0.227 0.000
M20-M25 Other joint disorders
0.773 0.227 0.000
C34.9 Bronchus or lung, unspecified
0.768 0.232 0.000
S02 Fracture of skull and facial bones
0.767 0.233 0.000
F32.1 Moderate depressive episode
0.766 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.766 0.234 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.766 0.234 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.765 0.235 0.000
H71 Cholesteatoma of middle ear
0.764 0.236 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.764 0.236 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.761 0.239 0.000
E29 Testicular dysfunction
0.759 0.240 0.000
E65 Localised adiposity
0.759 0.241 0.000
E27 Other disorders of adrenal gland
0.759 0.241 0.000
S22.4 Multiple fractures of ribs
0.759 0.241 0.000
E11.4 With neurological complications
0.758 0.242 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.757 0.243 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.757 0.243 0.000
M90 Osteopathies in diseases classified elsewhere
0.753 0.247 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.751 0.249 0.000
Chapter XXII Codes for special purposes
0.751 0.249 0.000
O36 Maternal care for other known or suspected foetal problems
0.751 0.249 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.749 0.251 0.000
O80-O84 Delivery
0.749 0.251 0.000
E14.3 With ophthalmic complications
0.749 0.251 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.748 0.252 0.000
H90-H95 Other disorders of ear
0.748 0.252 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.748 0.252 0.000
G62.8 Other specified polyneuropathies
0.748 0.252 0.000
B37 Candidiasis
0.746 0.254 0.000
H65 Nonsuppurative otitis media
0.743 0.256 0.000
E10.5 With peripheral circulatory complications
0.742 0.257 0.000
F80-F89 Disorders of psychological development
0.742 0.258 0.000
G60 Hereditary and idiopathic neuropathy
0.741 0.259 0.000
T79-T79 Certain early complications of trauma
0.740 0.260 0.000
T51 Toxic effect of alcohol
0.739 0.261 0.000
E66.9 Obesity, unspecified
0.738 0.262 0.000
E10.1 With ketoacidosis
0.736 0.264 0.000
M19 Other arthrosis
0.735 0.265 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.734 0.265 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
H02.8 Other specified disorders of eyelid
0.733 0.267 0.000
H27 Other disorders of lens
0.732 0.268 0.000
F41 Other anxiety disorders
0.731 0.269 0.000
H35.0 Background retinopathy and retinal vascular changes
0.731 0.269 0.000
E13.9 Without complications
0.731 0.269 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.730 0.270 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.730 0.270 0.000
Q21.1 Atrial septal defect
0.729 0.271 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.728 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
S60-S69 Injuries to the wrist and hand
0.727 0.273 0.000
F32.0 Mild depressive episode
0.727 0.273 0.000
M60-M63 Disorders of muscles
0.726 0.274 0.000
E22 Hyperfunction of pituitary gland
0.723 0.276 0.000
H60-H62 Diseases of external ear
0.721 0.279 0.000
T45.0 Antiallergic and antiemetic drugs
0.717 0.283 0.000
Chapter IX Diseases of the circulatory system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M25 Other joint disorders, not elsewhere classified
0.716 0.284 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.716 0.284 0.000
T91 Sequelae of injuries of neck and trunk
0.716 0.284 0.000
S42 Fracture of shoulder and upper arm
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
Q60-Q64 Congenital malformations of the urinary system
0.715 0.285 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.715 0.285 0.000
F34 Persistent mood [affective] disorders
0.715 0.285 0.000
F39 Unspecified mood [affective] disorder
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
S01.1 Open wound of eyelid and periocular area
0.713 0.287 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.713 0.287 0.000
F32.8 Other depressive episodes
0.712 0.288 0.000
E11.8 With unspecified complications
0.712 0.288 0.000
E11.7 With multiple complications
0.712 0.288 0.000
E11.6 With other specified complications
0.712 0.288 0.000
E11.1 With ketoacidosis
0.712 0.288 0.000
O41 Other disorders of amniotic fluid and membranes
0.712 0.288 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.711 0.288 0.000
O20 Haemorrhage in early pregnancy
0.711 0.289 0.000
G35 Multiple sclerosis
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
E34 Other endocrine disorders
0.707 0.293 0.000
C34.0 Main bronchus
0.707 0.293 0.000
T93 Sequelae of injuries of lower limb
0.707 0.293 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.705 0.295 0.000
E10.8 With unspecified complications
0.704 0.296 0.000
E10.7 With multiple complications
0.704 0.296 0.000
E10.6 With other specified complications
0.704 0.296 0.000
E10.2 With renal complications
0.704 0.296 0.000
E10.0 With coma
0.704 0.296 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.702 0.298 0.000
H31 Other disorders of choroid
0.702 0.298 0.000
H30 Chorioretinal inflammation
0.702 0.298 0.000
H35.4 Peripheral retinal degeneration
0.699 0.301 0.000
I60-I69 Cerebrovascular diseases
0.699 0.301 0.000
H54.4 Blindness, one eye
0.698 0.301 0.000
F99-F99 Unspecified mental disorder
0.698 0.302 0.000
S27.0 Traumatic pneumothorax
0.698 0.302 0.000
O00-O08 Pregnancy with abortive outcome
0.698 0.302 0.000
E24 Cushing's syndrome
0.698 0.302 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
T66-T78 Other and unspecified effects of external causes
0.696 0.303 0.000
M70-M79 Other soft tissue disorders
0.696 0.303 0.000
S22.5 Flail chest
0.696 0.304 0.000
F33 Recurrent depressive disorder
0.696 0.304 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.696 0.304 0.000
H55 Nystagmus and other irregular eye movements
0.695 0.305 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.695 0.305 0.000
H35.6 Retinal haemorrhage
0.694 0.306 0.000
G80 Infantile cerebral palsy
0.693 0.307 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.692 0.308 0.000
B37.0 Candidal stomatitis
0.692 0.308 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.690 0.310 0.000
H26.8 Other specified cataract
0.687 0.313 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.687 0.313 0.000
O85-O92 Complications predominantly related to the puerperium
0.685 0.315 0.000
G96 Other disorders of central nervous system
0.684 0.316 0.000
G61 Inflammatory polyneuropathy
0.684 0.316 0.000
G64 Other disorders of peripheral nervous system
0.684 0.316 0.000
S22.3 Fracture of rib
0.683 0.317 0.000
H26.2 Complicated cataract
0.683 0.317 0.000
M40-M43 Deforming dorsopathies
0.682 0.318 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.682 0.318 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.681 0.319 0.000
S29 Other and unspecified injuries of thorax
0.680 0.319 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.680 0.319 0.000
S26 Injury of heart
0.680 0.319 0.000
S25 Injury of blood vessels of thorax
0.680 0.319 0.000
S24 Injury of nerves and spinal cord at thorax level
0.680 0.319 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.680 0.319 0.000
S21 Open wound of thorax
0.680 0.319 0.000
O30 Multiple gestation
0.679 0.321 0.000
H40-H42 Glaucoma
0.677 0.323 0.000
M35 Other systemic involvement of connective tissue
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
D45 Polycythaemia vera
0.676 0.324 0.000
H35.9 Retinal disorder, unspecified
0.676 0.324 0.000
H35.7 Separation of retinal layers
0.676 0.324 0.000
H35.5 Hereditary retinal dystrophy
0.676 0.324 0.000
H35.2 Other proliferative retinopathy
0.676 0.324 0.000
H35.1 Retinopathy of prematurity
0.676 0.324 0.000
M25.5 Pain in joint
0.676 0.324 0.000
H35.8 Other specified retinal disorders
0.676 0.324 0.000
Q50-Q56 Congenital malformations of genital organs
0.675 0.325 0.000
T90 Sequelae of injuries of head
0.674 0.326 0.000
O40 Polyhydramnios
0.674 0.326 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
Y85 Sequelae of transport accidents
0.674 0.326 0.000
S22.2 Fracture of sternum
0.673 0.327 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.673 0.327 0.000
S22.40 Multiple fractures of ribs (closed)
0.672 0.328 0.000
S05 Injury of eye and orbit
0.672 0.328 0.000
C64-C68 Malignant neoplasms of urinary tract
0.672 0.328 0.000
G47 Sleep disorders
0.671 0.329 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.671 0.329 0.000
F31.8 Other bipolar affective disorders
0.670 0.329 0.000
F31.7 Bipolar affective disorder, currently in remission
0.670 0.329 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.670 0.329 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.670 0.329 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.670 0.329 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.670 0.329 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.670 0.329 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.670 0.330 0.000
F41.2 Mixed anxiety and depressive disorder
0.669 0.331 0.000
C78.2 Secondary malignant neoplasm of pleura
0.669 0.331 0.000
M90.7 Fracture of bone in neoplastic disease
0.669 0.331 0.000
T43.9 Psychotropic drug, unspecified
0.668 0.332 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
T43.6 Psychostimulants with abuse potential
0.668 0.332 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.668 0.332 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.668 0.332 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.668 0.332 0.000
G40 Epilepsy
0.668 0.332 0.000
H72.8 Other perforations of tympanic membrane
0.668 0.332 0.000
T92 Sequelae of injuries of upper limb
0.667 0.332 0.000
M16.3 Other dysplastic coxarthrosis
0.667 0.333 0.000
E28 Ovarian dysfunction
0.666 0.334 0.000
M16.7 Other secondary coxarthrosis
0.666 0.334 0.000
E10.4 With neurological complications
0.666 0.334 0.000
M88 Paget's disease of bone [osteitis deformans]
0.666 0.334 0.000
S40 Superficial injury of shoulder and upper arm
0.665 0.335 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.665 0.335 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.665 0.335 0.000
Q35-Q37 Cleft lip and cleft palate
0.665 0.335 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.665 0.335 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.665 0.335 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.665 0.335 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.665 0.335 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.663 0.337 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.663 0.337 0.000
S27.3 Other injuries of lung
0.663 0.337 0.000
M85 Other disorders of bone density and structure
0.663 0.337 0.000
S01.9 Open wound of head, part unspecified
0.662 0.338 0.000
E00-E07 Disorders of thyroid gland
0.662 0.338 0.000
S06 Intracranial injury
0.662 0.338 0.000
G62.2 Polyneuropathy due to other toxic agents
0.662 0.338 0.000
G62.1 Alcoholic polyneuropathy
0.662 0.338 0.000
G62.0 Drug-induced polyneuropathy
0.662 0.338 0.000
M19.0 Primary arthrosis of other joints
0.662 0.338 0.000
S22.0 Fracture of thoracic vertebra
0.662 0.338 0.000
E14.8 With unspecified complications
0.661 0.339 0.000
E14.7 With multiple complications
0.661 0.339 0.000
E14.6 With other specified complications
0.661 0.339 0.000
E14.5 With peripheral circulatory complications
0.661 0.339 0.000
E14.4 With neurological complications
0.661 0.339 0.000
E14.2 Withrenal complications
0.661 0.339 0.000
E14.1 With ketoacidosis
0.661 0.339 0.000
E14.0 With coma
0.661 0.339 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.660 0.340 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.660 0.340 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.660 0.340 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.660 0.340 0.000
T42.3 Barbiturates
0.660 0.340 0.000
T42.2 Succinimides and oxazolidinediones
0.660 0.340 0.000
T42.1 Iminostilbenes
0.660 0.340 0.000
T42.0 Hydantoin derivatives
0.660 0.340 0.000
Q23 Congenital malformations of aortic and mitral valves
0.660 0.340 0.000
Y43 Primarily systemic agents
0.659 0.341 0.000
O43 Placental disorders
0.658 0.342 0.000
E67 Other hyperalimentation
0.657 0.342 0.000
E68 Sequelae of hyperalimentation
0.657 0.342 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.657 0.343 0.000
S02.4 Fracture of malar and maxillary bones
0.657 0.343 0.000
M50-M54 Other dorsopathies
0.656 0.344 0.000
G91 Hydrocephalus
0.656 0.344 0.000
C34.2 Middle lobe, bronchus or lung
0.655 0.345 0.000
M89 Other disorders of bone
0.655 0.345 0.000
M15 Polyarthrosis
0.655 0.345 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.654 0.346 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.653 0.347 0.000
E32 Diseases of thymus
0.653 0.347 0.000
E31 Polyglandular dysfunction
0.653 0.347 0.000
E30 Disorders of puberty, not elsewhere classified
0.653 0.347 0.000
E26 Hyperaldosteronism
0.653 0.347 0.000
E25 Adrenogenital disorders
0.653 0.347 0.000
E20 Hypoparathyroidism
0.653 0.347 0.000
H74 Other disorders of middle ear and mastoid
0.652 0.348 0.000
E29.1 Testicular hypofunction
0.651 0.349 0.000
S01.7 Multiple open wounds of head
0.651 0.349 0.000
W00-W19 Falls
0.651 0.349 0.000
M65-M68 Disorders of synovium and tendon
0.650 0.350 0.000
H00 Hordeolum and chalazion
0.650 0.350 0.000
B99-B99 Other infectious diseases
0.650 0.350 0.000
I80 Phlebitis and thrombophlebitis
0.649 0.351 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.647 0.352 0.000
S70-S79 Injuries to the hip and thigh
0.647 0.353 0.000
G83 Other paralytic syndromes
0.647 0.353 0.000
S20 Superficial injury of thorax
0.645 0.355 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.645 0.355 0.000
H70 Mastoiditis and related conditions
0.645 0.355 0.000
H69 Other disorders of Eustachian tube
0.645 0.355 0.000
H68 Eustachian salpingitis and obstruction
0.645 0.355 0.000
H67 Otitis media in diseases classified elsewhere
0.645 0.355 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.645 0.355 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.644 0.355 0.000
O21 Excessive vomiting in pregnancy
0.644 0.356 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.644 0.356 0.000
S89 Other and unspecified injuries of lower leg
0.644 0.356 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.643 0.357 0.000
M86 Osteomyelitis
0.642 0.357 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.641 0.359 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.641 0.359 0.000
T39.4 Antirheumatics, not elsewhere classified
0.641 0.359 0.000
T39.2 Pyrazolone derivatives
0.641 0.359 0.000
H54.0 Blindness, both eyes
0.641 0.359 0.000
S08 Traumatic amputation of part of head
0.640 0.360 0.000
S07 Crushing injury of head
0.640 0.360 0.000
S04 Injury of cranial nerves
0.640 0.360 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.640 0.360 0.000
O36.6 Maternal care for excessive foetal growth
0.640 0.360 0.000
V80-V89 Other land transport accidents
0.639 0.361 0.000
H05 Disorders of orbit
0.639 0.361 0.000
M87 Osteonecrosis
0.639 0.361 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.638 0.362 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.637 0.363 0.000
H66 Suppurative and unspecified otitis media
0.636 0.364 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.636 0.364 0.000
O24 Diabetes mellitus in pregnancy
0.635 0.364 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.635 0.364 0.000
G90 Disorders of autonomic nervous system
0.635 0.364 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.635 0.364 0.000
G92 Toxic encephalopathy
0.635 0.364 0.000
H26.3 Drug-induced cataract
0.635 0.365 0.000
H26.1 Traumatic cataract
0.635 0.365 0.000
H26.0 Infantile, juvenile and presenile cataract
0.635 0.365 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.635 0.365 0.000
F30.9 Manic episode, unspecified
0.634 0.366 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.634 0.366 0.000
B15-B19 Viral hepatitis
0.634 0.366 0.000
T98 Sequelae of other and unspecified effects of external causes
0.633 0.367 0.000
T95 Sequelae of burns, corrosions and frostbite
0.633 0.367 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.633 0.367 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.633 0.367 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.633 0.367 0.000
S68 Traumatic amputation of wrist and hand
0.633 0.367 0.000
G30-G32 Other degenerative diseases of the nervous system
0.632 0.368 0.000
M94 Other disorders of cartilage
0.631 0.368 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.631 0.369 0.000
H34 Retinal vascular occlusions
0.631 0.369 0.000
H02.4 Ptosis of eyelid
0.630 0.369 0.000
G20-G26 Extrapyramidal and movement disorders
0.630 0.370 0.000
H02.1 Ectropion of eyelid
0.630 0.370 0.000
S22.9 Fracture of bony thorax, part unspecified
0.630 0.370 0.000
S22.8 Fracture of other parts of bony thorax
0.630 0.370 0.000
S22.1 Multiple fractures of thoracic spine
0.630 0.370 0.000
E50-E64 Other nutritional deficiencies
0.630 0.370 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.630 0.370 0.000
O46.9 Antepartum haemorrhage, unspecified
0.630 0.370 0.000
O80 Single spontaneous delivery
0.629 0.371 0.000
H26.4 After-cataract
0.629 0.371 0.000
H43-H45 Disorders of vitreous body and globe
0.628 0.372 0.000
S01.8 Open wound of other parts of head
0.626 0.374 0.000
H80-H83 Diseases of inner ear
0.625 0.375 0.000
M45-M49 Spondylopathies
0.625 0.375 0.000
H90 Conductive and sensorineural hearing loss
0.625 0.375 0.000
O45 Premature separation of placenta [abruptio placentae]
0.625 0.375 0.000
O44 Placenta praevia
0.625 0.375 0.000
O33 Maternal care for known or suspected disproportion
0.625 0.375 0.000
O31 Complications specific to multiple gestation
0.625 0.375 0.000
O26.8 Other specified pregnancy-related conditions
0.624 0.376 0.000
M35.3 Polymyalgia rheumatica
0.624 0.376 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.623 0.377 0.000
M16.0 Primary coxarthrosis, bilateral
0.623 0.377 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.623 0.377 0.000
H11 Other disorders of conjunctiva
0.622 0.378 0.000
S02.3 Fracture of orbital floor
0.622 0.378 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.622 0.378 0.000
G71 Primary disorders of muscles
0.621 0.379 0.000
G82 Paraplegia and tetraplegia
0.621 0.379 0.000
M81 Osteoporosis without pathological fracture
0.620 0.380 0.000
F41.1 Generalised anxiety disorder
0.620 0.380 0.000
X60-X84 Intentional self-harm
0.619 0.381 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.619 0.381 0.000
G44 Other headache syndromes
0.619 0.381 0.000
W20-W49 Exposure to inanimate mechanical forces
0.619 0.381 0.000
S50 Superficial injury of forearm
0.618 0.382 0.000
C79.2 Secondary malignant neoplasm of skin
0.618 0.382 0.000
O29 Complications of anaesthesia during pregnancy
0.618 0.382 0.000
O28 Abnormal findings on antenatal screening of mother
0.618 0.382 0.000
O23 Infections of genito-urinary tract in pregnancy
0.618 0.382 0.000
O22 Venous complications in pregnancy
0.618 0.382 0.000
O25 Malnutrition in pregnancy
0.618 0.382 0.000
E23 Hypofunction and other disorders of pituitary gland
0.617 0.382 0.000
F60 Specific personality disorders
0.617 0.383 0.000
G93 Other disorders of brain
0.617 0.383 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.617 0.383 0.000
M84 Disorders of continuity of bone
0.616 0.384 0.000
T51.9 Alcohol, unspecified
0.616 0.384 0.000
B35 Dermatophytosis
0.616 0.384 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.616 0.384 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.616 0.384 0.000
S01.2 Open wound of nose
0.616 0.384 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.615 0.384 0.000
S37 Injury of urinary and pelvic organs
0.615 0.384 0.000
S36 Injury of intra-abdominal organs
0.615 0.384 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.615 0.384 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.615 0.384 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.615 0.384 0.000
S31 Open wound of abdomen, lower back and pelvis
0.615 0.384 0.000
S32 Fracture of lumbar spine and pelvis
0.615 0.385 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.615 0.385 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.615 0.385 0.000
C32 Malignant neoplasm of larynx
0.615 0.385 0.000
C31 Malignant neoplasm of accessory sinuses
0.615 0.385 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.615 0.385 0.000
C37 Malignant neoplasm of thymus
0.615 0.385 0.000
C33 Malignant neoplasm of trachea
0.615 0.385 0.000
I61 Intracerebral haemorrhage
0.614 0.386 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.614 0.386 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.613 0.387 0.000
S48 Traumatic amputation of shoulder and upper arm
0.613 0.387 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.613 0.387 0.000
S44 Injury of nerves at shoulder and upper arm level
0.613 0.387 0.000
S41 Open wound of shoulder and upper arm
0.613 0.387 0.000
S47 Crushing injury of shoulder and upper arm
0.613 0.387 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.613 0.387 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.613 0.387 0.000
S80 Superficial injury of lower leg
0.613 0.387 0.000
H54.7 Unspecified visual loss
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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