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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114162361
log Bayes Factor = 7.44447
Chromosome 1   position 174,575,642  (GRCh37) Explore rs114162361 on Ensembl!
Variant rs114162361 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
N81 Female genital prolapse
0.997 0.003 0.000
J34 Other disorders of nose and nasal sinuses
0.996 0.004 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.996 0.004 0.000
Chapter II Neoplasms
0.982 0.018 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.981 0.019 0.000
N81.4 Uterovaginal prolapse, unspecified
0.979 0.021 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.975 0.025 0.000
Chapter VIII Diseases of the ear and mastoid process
0.972 0.028 0.000
Chapter XI Diseases of the digestive system
0.969 0.031 0.000
Chapter XXI Factors influencing health status and contact with health services
0.958 0.042 0.000
J34.2 Deviated nasal septum
0.957 0.043 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.952 0.048 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.945 0.055 0.000
K35-K38 Diseases of appendix
0.945 0.055 0.000
J20-J22 Other acute lower respiratory infections
0.942 0.058 0.000
N81.6 Rectocele
0.937 0.063 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.935 0.065 0.000
Z51 Other medical care
0.926 0.074 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.918 0.082 0.000
N60-N64 Disorders of breast
0.917 0.083 0.000
K35 Acute appendicitis
0.909 0.091 0.000
Chapter XX External causes of morbidity and mortality
0.904 0.096 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.903 0.097 0.000
J22 Unspecified acute lower respiratory infection
0.900 0.100 0.000
Z51.5 Palliative care
0.898 0.102 0.000
K50-K52 Noninfective enteritis and colitis
0.897 0.103 0.000
H65-H75 Diseases of middle ear and mastoid
0.896 0.104 0.000
N81.3 Complete uterovaginal prolapse
0.896 0.104 0.000
C15-C26 Malignant neoplasms of digestive organs
0.895 0.105 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.893 0.107 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.889 0.111 0.000
R50-R69 General symptoms and signs
0.887 0.113 0.000
J32 Chronic sinusitis
0.886 0.114 0.000
K35.9 Acute appendicitis, unspecified
0.881 0.119 0.000
N81.1 Cystocele
0.881 0.119 0.000
J36 Peritonsillar abscess
0.879 0.121 0.000
N60 Benign mammary dysplasia
0.877 0.123 0.000
K51 Ulcerative colitis
0.871 0.129 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.870 0.130 0.000
J40-J47 Chronic lower respiratory diseases
0.869 0.131 0.000
Z43 Attention to artificial openings
0.868 0.132 0.000
R51 Headache
0.852 0.148 0.000
J34.3 Hypertrophy of nasal turbinates
0.851 0.149 0.000
N10-N16 Renal tubulo-interstitial diseases
0.851 0.149 0.000
H80-H83 Diseases of inner ear
0.843 0.157 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.842 0.158 0.000
N81.5 Vaginal enterocele
0.839 0.161 0.000
N84 Polyp of female genital tract
0.836 0.164 0.000
H90-H95 Other disorders of ear
0.833 0.167 0.000
N25-N29 Other disorders of kidney and ureter
0.831 0.169 0.000
N89 Other noninflammatory disorders of vagina
0.830 0.170 0.000
C20 Malignant neoplasm of rectum
0.828 0.172 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.828 0.172 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
H72 Perforation of tympanic membrane
0.823 0.177 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.823 0.177 0.000
K37 Unspecified appendicitis
0.819 0.181 0.000
K51.9 Ulcerative colitis, unspecified
0.815 0.185 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.814 0.186 0.000
Z42 Follow-up care involving plastic surgery
0.813 0.187 0.000
J43 Emphysema
0.810 0.189 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.809 0.191 0.000
C34 Malignant neoplasm of bronchus and lung
0.809 0.191 0.000
J38.7 Other diseases of larynx
0.808 0.192 0.000
N81.9 Female genital prolapse, unspecified
0.805 0.195 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.804 0.196 0.000
K02 Dental caries
0.803 0.197 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.802 0.198 0.000
J32.9 Chronic sinusitis, unspecified
0.799 0.201 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.799 0.201 0.000
J00-J06 Acute upper respiratory infections
0.798 0.202 0.000
N93 Other abnormal uterine and vaginal bleeding
0.798 0.202 0.000
K13 Other diseases of lip and oral mucosa
0.798 0.202 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.797 0.203 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.791 0.209 0.000
C16 Malignant neoplasm of stomach
0.789 0.211 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.789 0.211 0.000
R05 Cough
0.788 0.212 0.000
D45 Polycythaemia vera
0.787 0.213 0.000
N84.1 Polyp of cervix uteri
0.787 0.213 0.000
N81.8 Other female genital prolapse
0.786 0.214 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.785 0.215 0.000
Z51.2 Other chemotherapy
0.783 0.217 0.000
Z49 Care involving dialysis
0.783 0.217 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.780 0.220 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.775 0.225 0.000
Z43.2 Attention to ileostomy
0.774 0.226 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.771 0.229 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.771 0.229 0.000
N86 Erosion and ectropion of cervix uteri
0.770 0.230 0.000
J43.9 Emphysema, unspecified
0.769 0.231 0.000
R04 Haemorrhage from respiratory passages
0.765 0.235 0.000
K08 Other disorders of teeth and supporting structures
0.764 0.236 0.000
S20-S29 Injuries to the thorax
0.763 0.237 0.000
N60.1 Diffuse cystic mastopathy
0.763 0.237 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.760 0.240 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.760 0.240 0.000
N99-N99 Other disorders of the genitourinary system
0.760 0.240 0.000
R69 Unknown and unspecified causes of morbidity
0.759 0.241 0.000
Chapter XXII Codes for special purposes
0.758 0.242 0.000
D00-D09 In situ neoplasms
0.758 0.242 0.000
K65-K67 Diseases of peritoneum
0.756 0.244 0.000
D46 Myelodysplastic syndromes
0.755 0.245 0.000
C79 Secondary malignant neoplasm of other sites
0.754 0.246 0.000
N64 Other disorders of breast
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.752 0.248 0.000
S60-S69 Injuries to the wrist and hand
0.751 0.249 0.000
R94 Abnormal results of function studies
0.750 0.250 0.000
Z48 Other surgical follow-up care
0.749 0.251 0.000
K05 Gingivitis and periodontal diseases
0.748 0.252 0.000
Z45 Adjustment and management of implanted device
0.746 0.254 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.743 0.257 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.741 0.259 0.000
Z40 Prophylactic surgery
0.741 0.259 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.741 0.259 0.000
K14 Diseases of tongue
0.741 0.259 0.000
T66-T78 Other and unspecified effects of external causes
0.739 0.261 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.739 0.261 0.000
N97 Female infertility
0.738 0.262 0.000
R60 Oedema, not elsewhere classified
0.736 0.264 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.735 0.265 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
K13.0 Diseases of lips
0.730 0.270 0.000
C34.9 Bronchus or lung, unspecified
0.730 0.270 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.729 0.271 0.000
N00-N08 Glomerular diseases
0.728 0.272 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.727 0.273 0.000
J46 Status asthmaticus
0.725 0.275 0.000
N60.4 Mammary duct ectasia
0.723 0.277 0.000
H90 Conductive and sensorineural hearing loss
0.722 0.278 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.721 0.279 0.000
R59 Enlarged lymph nodes
0.720 0.280 0.000
K02.9 Dental caries, unspecified
0.720 0.280 0.000
K51.8 Other ulcerative colitis
0.718 0.282 0.000
J95-J99 Other diseases of the respiratory system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J37 Chronic laryngitis and laryngotracheitis
0.716 0.284 0.000
N61 Inflammatory disorders of breast
0.715 0.285 0.000
N81.0 Female urethrocele
0.714 0.285 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.714 0.286 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.714 0.286 0.000
N98 Complications associated with artificial fertilisation
0.714 0.286 0.000
N91 Absent, scanty and rare menstruation
0.714 0.286 0.000
N82 Fistulae involving female genital tract
0.714 0.286 0.000
N96 Habitual aborter
0.714 0.286 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.713 0.287 0.000
C64-C68 Malignant neoplasms of urinary tract
0.712 0.288 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.711 0.289 0.000
R52 Pain, not elsewhere classified
0.711 0.289 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.711 0.289 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.710 0.290 0.000
J44 Other chronic obstructive pulmonary disease
0.709 0.291 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.708 0.292 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.708 0.292 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.707 0.293 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.706 0.294 0.000
K70-K77 Diseases of liver
0.706 0.294 0.000
H73 Other disorders of tympanic membrane
0.705 0.294 0.000
Z57 Occupational exposure to risk-factors
0.705 0.295 0.000
J38.2 Nodules of vocal cords
0.704 0.295 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.704 0.296 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.704 0.296 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.704 0.296 0.000
N60.8 Other benign mammary dysplasias
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.701 0.299 0.000
N60.3 Fibrosclerosis of breast
0.699 0.301 0.000
N88 Other noninflammatory disorders of cervix uteri
0.697 0.303 0.000
T93 Sequelae of injuries of lower limb
0.696 0.304 0.000
K85 Acute pancreatitis
0.695 0.305 0.000
H81 Disorders of vestibular function
0.693 0.307 0.000
N40-N51 Diseases of male genital organs
0.693 0.307 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.693 0.307 0.000
H83 Other diseases of inner ear
0.692 0.308 0.000
C50-C50 Malignant neoplasm of breast
0.691 0.309 0.000
R04.2 Haemoptysis
0.691 0.309 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.689 0.311 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.688 0.312 0.000
R47-R49 Symptoms and signs involving speech and voice
0.686 0.314 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.686 0.314 0.000
Z52 Donors of organs and tissues
0.685 0.314 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.683 0.317 0.000
Z54 Convalescence
0.682 0.317 0.000
Z44 Fitting and adjustment of external prosthetic device
0.682 0.317 0.000
C32 Malignant neoplasm of larynx
0.681 0.319 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
D37.5 Rectum
0.680 0.320 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.679 0.321 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.678 0.322 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.678 0.322 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.678 0.322 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.678 0.322 0.000
K38 Other diseases of appendix
0.677 0.322 0.000
K36 Other appendicitis
0.677 0.322 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.676 0.324 0.000
J60-J70 Lung diseases due to external agents
0.676 0.324 0.000
C16.9 Stomach, unspecified
0.676 0.324 0.000
J39 Other diseases of upper respiratory tract
0.675 0.325 0.000
J21 Acute bronchiolitis
0.675 0.325 0.000
J20 Acute bronchitis
0.675 0.325 0.000
K35.3 Acute appendicitis with localized peritonitis
0.675 0.325 0.000
J35 Chronic diseases of tonsils and adenoids
0.674 0.325 0.000
R11 Nausea and vomiting
0.674 0.326 0.000
C73 Malignant neoplasm of thyroid gland
0.673 0.327 0.000
W20-W49 Exposure to inanimate mechanical forces
0.672 0.328 0.000
H92 Otalgia and effusion of ear
0.672 0.328 0.000
M65-M68 Disorders of synovium and tendon
0.672 0.328 0.000
N60.0 Solitary cyst of breast
0.671 0.328 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
T33-T35 Frostbite
0.671 0.329 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.671 0.329 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.671 0.329 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.671 0.329 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.671 0.329 0.000
T00-T07 Injuries involving multiple body regions
0.671 0.329 0.000
N10 Acute tubulo-interstitial nephritis
0.670 0.330 0.000
H60-H62 Diseases of external ear
0.669 0.331 0.000
K07 Dentofacial anomalies [including malocclusion]
0.668 0.332 0.000
N70 Salpingitis and oophoritis
0.667 0.333 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.666 0.334 0.000
Y40 Systemic antibiotics
0.665 0.334 0.000
Z43.3 Attention to colostomy
0.665 0.335 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.664 0.336 0.000
Z51.9 Medical care, unspecified
0.664 0.336 0.000
Z51.6 Desensitisation to allergens
0.664 0.336 0.000
S27 Injury of other and unspecified intrathoracic organs
0.663 0.337 0.000
J00 Acute nasopharyngitis [common cold]
0.662 0.338 0.000
R42 Dizziness and giddiness
0.662 0.338 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.662 0.338 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.661 0.339 0.000
R09.1 Pleurisy
0.661 0.339 0.000
Q00-Q07 Congenital malformations of the nervous system
0.659 0.341 0.000
Z50 Care involving use of rehabilitation procedures
0.659 0.341 0.000
K10 Other diseases of jaws
0.658 0.341 0.000
K09 Cysts of oral region, not elsewhere classified
0.658 0.341 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.658 0.341 0.000
K03 Other diseases of hard tissues of teeth
0.658 0.341 0.000
K00 Disorders of tooth development and eruption
0.658 0.341 0.000
K83 Other diseases of biliary tract
0.658 0.342 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.657 0.343 0.000
H66 Suppurative and unspecified otitis media
0.657 0.343 0.000
R45 Symptoms and signs involving emotional state
0.657 0.343 0.000
J38.1 Polyp of vocal cord and larynx
0.657 0.343 0.000
C15 Malignant neoplasm of oesophagus
0.656 0.344 0.000
J38.3 Other diseases of vocal cords
0.656 0.344 0.000
M50-M54 Other dorsopathies
0.655 0.345 0.000
R13 Dysphagia
0.655 0.345 0.000
C34.1 Upper lobe, bronchus or lung
0.653 0.346 0.000
Z41 Procedures for purposes other than remedying health state
0.653 0.347 0.000
K01 Embedded and impacted teeth
0.653 0.347 0.000
Chapter VII Diseases of the eye and adnexa
0.652 0.348 0.000
J32.0 Chronic maxillary sinusitis
0.652 0.348 0.000
K35.8 Acute appendicitis, other and unspecified
0.652 0.348 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.652 0.348 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.652 0.348 0.000
S40-S49 Injuries to the shoulder and upper arm
0.651 0.348 0.000
R94.5 Abnormal results of liver function studies
0.651 0.349 0.000
S70-S79 Injuries to the hip and thigh
0.651 0.349 0.000
X60-X84 Intentional self-harm
0.651 0.349 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.648 0.352 0.000
Y35-Y36 Legal intervention and operations of war
0.648 0.352 0.000
Y10-Y34 Event of undetermined intent
0.648 0.352 0.000
Y00-Y09 Assault
0.648 0.352 0.000
X85-X99 Assault
0.648 0.352 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.648 0.352 0.000
X50-X57 Overexertion, travel and privation
0.648 0.352 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.648 0.352 0.000
X30-X39 Exposure to forces of nature
0.648 0.352 0.000
X20-X29 Contact with venomous animals and plants
0.648 0.352 0.000
X10-X19 Contact with heat and hot substances
0.648 0.352 0.000
X00-X09 Exposure to smoke, fire and flames
0.648 0.352 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.648 0.352 0.000
W75-W84 Other accidental threats to breathing
0.648 0.352 0.000
W65-W74 Accidental drowning and submersion
0.648 0.352 0.000
W50-W64 Exposure to animate mechanical forces
0.648 0.352 0.000
V98-V99 Other and unspecified transport accidents
0.648 0.352 0.000
V95-V97 Air and space transport accidents
0.648 0.352 0.000
V90-V94 Water transport accidents
0.648 0.352 0.000
V80-V89 Other land transport accidents
0.648 0.352 0.000
V70-V79 Bus occupant injured in transport accident
0.648 0.352 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.648 0.352 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.648 0.352 0.000
V40-V49 Car occupant injured in transport accident
0.648 0.352 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.648 0.352 0.000
V10-V19 Pedal cyclist injured in transport accident
0.648 0.352 0.000
V01-V09 Pedestrian injured in transport accident
0.648 0.352 0.000
J38.6 Stenosis of larynx
0.647 0.353 0.000
J38.5 Laryngeal spasm
0.647 0.353 0.000
J38.4 Oedema of larynx
0.647 0.353 0.000
J38.0 Paralysis of vocal cords and larynx
0.647 0.353 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.647 0.353 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.646 0.353 0.000
R50 Fever of unknown origin
0.646 0.354 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.645 0.355 0.000
Z43.1 Attention to gastrostomy
0.645 0.355 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.644 0.356 0.000
S90-S99 Injuries to the ankle and foot
0.644 0.356 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.644 0.356 0.000
T90 Sequelae of injuries of head
0.644 0.356 0.000
R26 Abnormalities of gait and mobility
0.643 0.357 0.000
K12 Stomatitis and related lesions
0.643 0.357 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.642 0.357 0.000
H74 Other disorders of middle ear and mastoid
0.642 0.357 0.000
H70 Mastoiditis and related conditions
0.642 0.357 0.000
H69 Other disorders of Eustachian tube
0.642 0.357 0.000
H68 Eustachian salpingitis and obstruction
0.642 0.357 0.000
H67 Otitis media in diseases classified elsewhere
0.642 0.357 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.642 0.358 0.000
V20-V29 Motorcycle rider injured in transport accident
0.642 0.358 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.641 0.359 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.641 0.359 0.000
C21 Malignant neoplasm of anus and anal canal
0.641 0.359 0.000
C17 Malignant neoplasm of small intestine
0.641 0.359 0.000
C23 Malignant neoplasm of gallbladder
0.641 0.359 0.000
C51-C58 Malignant neoplasms of female genital organs
0.641 0.359 0.000
K52 Other non-infective gastro-enteritis and colitis
0.641 0.359 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.640 0.360 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.640 0.360 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.640 0.360 0.000
C77.0 Lymph nodes of head, face and neck
0.639 0.361 0.000
C01 Malignant neoplasm of base of tongue
0.639 0.361 0.000
C16.0 Cardia
0.638 0.362 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.638 0.362 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.638 0.362 0.000
C31 Malignant neoplasm of accessory sinuses
0.638 0.362 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.638 0.362 0.000
C37 Malignant neoplasm of thymus
0.638 0.362 0.000
C33 Malignant neoplasm of trachea
0.638 0.362 0.000
H71 Cholesteatoma of middle ear
0.637 0.363 0.000
R04.0 Epistaxis
0.636 0.364 0.000
K51.2 Ulcerative (chronic) proctitis
0.636 0.364 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.636 0.364 0.000
R62 Lack of expected normal physiological development
0.636 0.364 0.000
R57 Shock, not elsewhere classified
0.636 0.364 0.000
R64 Cachexia
0.636 0.364 0.000
R58 Haemorrhage, not elsewhere classified
0.636 0.364 0.000
N60.2 Fibroadenosis of breast
0.635 0.365 0.000
J32.8 Other chronic sinusitis
0.635 0.365 0.000
J32.4 Chronic pansinusitis
0.635 0.365 0.000
J32.3 Chronic sphenoidal sinusitis
0.635 0.365 0.000
J32.2 Chronic ethmoidal sinusitis
0.635 0.365 0.000
J32.1 Chronic frontal sinusitis
0.635 0.365 0.000
Q60-Q64 Congenital malformations of the urinary system
0.635 0.365 0.000
N64.9 Disorder of breast, unspecified
0.634 0.366 0.000
H65 Nonsuppurative otitis media
0.633 0.367 0.000
R73 Elevated blood glucose level
0.632 0.368 0.000
N81.2 Incomplete uterovaginal prolapse
0.630 0.370 0.000
N60.9 Benign mammary dysplasia, unspecified
0.629 0.371 0.000
C80 Malignant neoplasm without specification of site
0.629 0.371 0.000
H90.2 Conductive hearing loss, unspecified
0.628 0.372 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.626 0.373 0.000
Z49.0 Preparatory care for dialysis
0.626 0.373 0.000
Q50-Q56 Congenital malformations of genital organs
0.626 0.374 0.000
J09-J18 Influenza and pneumonia
0.626 0.374 0.000
K05.3 Chronic periodontitis
0.626 0.374 0.000
K51.5 Mucosal proctocolitis
0.624 0.375 0.000
K51.4 Pseudopolyposis of colon
0.624 0.375 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.624 0.375 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.624 0.375 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.623 0.376 0.000
J41 Simple and mucopurulent chronic bronchitis
0.623 0.377 0.000
R68 Other general symptoms and signs
0.623 0.377 0.000
Z43.9 Attention to unspecified artificial opening
0.623 0.377 0.000
Z43.8 Attention to other artificial openings
0.623 0.377 0.000
Z43.7 Attention to artificial vagina
0.623 0.377 0.000
Z43.5 Attention to cyctostomy
0.623 0.377 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.623 0.377 0.000
Z43.0 Attention to tracheostomy
0.623 0.377 0.000
Z63 Other problems related to primary support group, including family circumstances
0.621 0.378 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.621 0.379 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.621 0.379 0.000
R27 Other lack of coordination
0.621 0.379 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.618 0.382 0.000
Z45.2 Adjustment and management of vascular access device
0.618 0.382 0.000
R12 Heartburn
0.617 0.383 0.000
N13 Obstructive and reflux uropathy
0.615 0.385 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.615 0.385 0.000
K80 Cholelithiasis
0.615 0.385 0.000
D47.1 Chronic myeloproliferative disease
0.614 0.386 0.000
S80-S89 Injuries to the knee and lower leg
0.614 0.386 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.614 0.386 0.000
R61 Hyperhidrosis
0.613 0.387 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.612 0.388 0.000
M54 Dorsalgia
0.612 0.388 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.611 0.389 0.000
H80 Otosclerosis
0.611 0.389 0.000
Chapter V Mental and behavioural disorders
0.611 0.389 0.000
Z57.2 Occupational exposure to dust
0.611 0.389 0.000
R22.1 Localised swelling, mass and lump, neck
0.611 0.389 0.000
Z49.1 Extracorporeal dialysis
0.610 0.389 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.610 0.390 0.000
N15 Other renal tubulo-interstitial diseases
0.610 0.390 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.610 0.390 0.000
N11 Chronic tubulo-interstitial nephritis
0.610 0.390 0.000
Z48.0 Attention to surgical dressings and sutures
0.609 0.391 0.000
S64 Injury of nerves at wrist and hand level
0.609 0.391 0.000
C09 Malignant neoplasm of tonsil
0.607 0.392 0.000
T18 Foreign body in alimentary tract
0.607 0.393 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.607 0.393 0.000
R94.3 Abnormal results of cardiovascular function studies
0.607 0.393 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.605 0.395 0.000
R59.0 Localised enlarged lymph nodes
0.605 0.395 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.604 0.396 0.000
C77.8 Lymph nodes of multiple regions
0.603 0.397 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.603 0.397 0.000
C67 Malignant neoplasm of bladder
0.602 0.398 0.000
Z60 Problems related to social environment
0.602 0.398 0.000
Y86 Sequelae of other accidents
0.602 0.398 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.601 0.399 0.000
N45 Orchitis and epididymitis
0.601 0.399 0.000
K14.8 Other diseases of tongue
0.600 0.400 0.000
N84.9 Polyp of female genital tract, unspecified
0.599 0.400 0.000
N84.8 Polyp of other parts of female genital tract
0.599 0.400 0.000
N84.3 Polyp of vulva
0.599 0.400 0.000
N84.2 Polyp of vagina
0.599 0.400 0.000
N87 Dysplasia of cervix uteri
0.599 0.401 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.598 0.402 0.000
T78 Adverse effects, not elsewhere classified
0.598 0.402 0.000
Z47 Other orthopaedic follow-up care
0.597 0.403 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.597 0.403 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.597 0.403 0.000
M67 Other disorders of synovium and tendon
0.597 0.403 0.000
N28.0 Ischaemia and infarction of kidney
0.596 0.404 0.000
N02 Recurrent and persistent haematuria
0.596 0.404 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.596 0.404 0.000
N27 Small kidney of unknown cause
0.596 0.404 0.000
N25 Disorders resulting from impaired renal tubular function
0.596 0.404 0.000
N26 Unspecified contracted kidney
0.596 0.404 0.000
W00-W19 Falls
0.596 0.404 0.000
N28.1 Cyst of kidney, acquired
0.596 0.404 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.596 0.404 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.595 0.405 0.000
N89.7 Haematocolpos
0.595 0.405 0.000
N89.6 Tight hymenal ring
0.595 0.405 0.000
N89.5 Stricture and atresia of vagina
0.595 0.405 0.000
N89.4 Leukoplakia of vagina
0.595 0.405 0.000
N89.3 Dysplasia of vagina, unspecified
0.595 0.405 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.595 0.405 0.000
N89.1 Moderate vaginal dysplasia
0.595 0.405 0.000
N89.0 Mild vaginal dysplasia
0.595 0.405 0.000
Chapter VI Diseases of the nervous system
0.595 0.405 0.000
D41.4 Bladder
0.595 0.405 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.594 0.406 0.000
R60.9 Oedema, unspecified
0.594 0.406 0.000
N41 Inflammatory diseases of prostate
0.593 0.407 0.000
S27.0 Traumatic pneumothorax
0.591 0.408 0.000
Y59 Other and unspecified vaccines and biological substances
0.591 0.409 0.000
Y58 Bacterial vaccines
0.591 0.409 0.000
Y57 Other and unspecified drugs and medicaments
0.591 0.409 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.591 0.409 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.591 0.409 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.591 0.409 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.591 0.409 0.000
Y52 Agents primarily affecting the cardiovascular system
0.591 0.409 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.591 0.409 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.591 0.409 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.591 0.409 0.000
Y48 Anaesthetics and therapeutic gases
0.591 0.409 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.591 0.409 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.591 0.409 0.000
Y44 Agents primarily affecting blood constituents
0.591 0.409 0.000
K66 Other disorders of peritoneum
0.591 0.409 0.000
Z75 Problems related to medical facilities and other health care
0.591 0.409 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.591 0.409 0.000
Q80-Q89 Other congenital malformations
0.591 0.409 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.591 0.409 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.591 0.409 0.000
Q35-Q37 Cleft lip and cleft palate
0.591 0.409 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.591 0.409 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.591 0.409 0.000
N72 Inflammatory disease of cervix uteri
0.591 0.409 0.000
H72.8 Other perforations of tympanic membrane
0.590 0.410 0.000
H72.2 Other marginal perforations of tympanic membrane
0.590 0.410 0.000
H72.1 Attic perforation of tympanic membrane
0.590 0.410 0.000
H72.0 Central perforation of tympanic membrane
0.590 0.410 0.000
Z65 Problems related to other psychosocial circumstances
0.590 0.410 0.000
Z64 Problems related to certain psychosocial circumstances
0.590 0.410 0.000
Z62 Other problems related to upbringing
0.590 0.410 0.000
Z61 Problems related to negative life events in childhood
0.590 0.410 0.000
Z59 Problems related to housing and economic circumstances
0.590 0.410 0.000
Z58 Problems related to physical environment
0.590 0.410 0.000
Z56 Problems related to employment and unemployment
0.590 0.410 0.000
Z55 Problems related to education and literacy
0.590 0.410 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.590 0.410 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.590 0.410 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.590 0.410 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.589 0.411 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.589 0.411 0.000
Y43 Primarily systemic agents
0.589 0.411 0.000
J42 Unspecified chronic bronchitis
0.588 0.412 0.000
D04 Carcinoma in situ of skin
0.587 0.413 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.587 0.413 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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