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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114281340
log Bayes Factor = 22.5343
Chromosome 5   position 162,746,934  (GRCh37) Explore rs114281340 on Ensembl!
Variant rs114281340 is part of Cluster X0166

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
Z86 Personal history of certain other diseases
0.994 0.006 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.993 0.007 0.000
T81 Complications of procedures, not elsewhere classified
0.992 0.008 0.000
A30-A49 Other bacterial diseases
0.991 0.009 0.000
B95-B98 Bacterial, viral and other infectious agents
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.981 0.019 0.000
Chapter VI Diseases of the nervous system
0.980 0.020 0.000
I51 Complications and ill-defined descriptions of heart disease
0.980 0.020 0.000
Z86.4 Personal history of psychoactive substance abuse
0.978 0.022 0.000
E70-E90 Metabolic disorders
0.978 0.022 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.974 0.026 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.971 0.029 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.970 0.030 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.970 0.030 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.970 0.030 0.000
A41 Other septicaemia
0.970 0.030 0.000
J40-J47 Chronic lower respiratory diseases
0.969 0.031 0.000
C15-C26 Malignant neoplasms of digestive organs
0.969 0.031 0.000
I51.8 Other ill-defined heart diseases
0.965 0.035 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.961 0.039 0.000
G90-G99 Other disorders of the nervous system
0.958 0.042 0.000
I50 Heart failure
0.957 0.043 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.956 0.044 0.000
L03 Cellulitis
0.949 0.051 0.000
M65-M68 Disorders of synovium and tendon
0.949 0.051 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.948 0.052 0.000
J44 Other chronic obstructive pulmonary disease
0.946 0.054 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.940 0.060 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.939 0.061 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.936 0.064 0.000
I34 Nonrheumatic mitral valve disorders
0.936 0.064 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.935 0.065 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.935 0.065 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.934 0.066 0.000
A41.9 Septicaemia, unspecified
0.930 0.070 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.929 0.071 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.926 0.074 0.000
M20-M25 Other joint disorders
0.923 0.077 0.000
E87.6 Hypokalaemia
0.919 0.081 0.000
S60-S69 Injuries to the wrist and hand
0.918 0.082 0.000
Z53.8 Procedure not carried out for other reasons
0.918 0.082 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.916 0.084 0.000
M65 Synovitis and tenosynovitis
0.915 0.085 0.000
S80-S89 Injuries to the knee and lower leg
0.913 0.087 0.000
A49 Bacterial infection of unspecified site
0.913 0.087 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.913 0.087 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.911 0.089 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.909 0.091 0.000
Chapter V Mental and behavioural disorders
0.909 0.091 0.000
I27 Other pulmonary heart diseases
0.909 0.091 0.000
Z98 Other postsurgical states
0.909 0.091 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.909 0.091 0.000
L20-L30 Dermatitis and eczema
0.909 0.091 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.907 0.093 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.906 0.094 0.000
C20 Malignant neoplasm of rectum
0.904 0.096 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.903 0.097 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.903 0.097 0.000
Chapter XIV Diseases of the genitourinary system
0.901 0.099 0.000
Z87 Personal history of other diseases and conditions
0.900 0.100 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.898 0.102 0.000
J95-J99 Other diseases of the respiratory system
0.898 0.102 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.897 0.103 0.000
L03.1 Cellulitis of other parts of limb
0.896 0.104 0.000
C34 Malignant neoplasm of bronchus and lung
0.893 0.107 0.000
I34.0 Mitral (valve) insufficiency
0.893 0.107 0.000
J90-J94 Other diseases of pleura
0.890 0.110 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.884 0.116 0.000
J00-J06 Acute upper respiratory infections
0.882 0.118 0.000
M50-M54 Other dorsopathies
0.882 0.118 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.881 0.119 0.000
Z92 Personal history of medical treatment
0.879 0.121 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.877 0.123 0.000
I05-I09 Chronic rheumatic heart diseases
0.876 0.124 0.000
N17-N19 Renal failure
0.873 0.127 0.000
Z93 Artificial opening status
0.873 0.127 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.871 0.129 0.000
I27.0 Primary pulmonary hypertension
0.870 0.130 0.000
Z46 Fitting and adjustment of other devices
0.866 0.134 0.000
Z98.0 Intestinal bypass and anastomosis status
0.866 0.134 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.866 0.134 0.000
I50.0 Congestive heart failure
0.865 0.135 0.000
N40-N51 Diseases of male genital organs
0.864 0.136 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.864 0.136 0.000
Z42 Follow-up care involving plastic surgery
0.863 0.137 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.863 0.137 0.000
Z87.0 Personal history of diseases of the respiratory system
0.863 0.137 0.000
L08 Other local infections of skin and subcutaneous tissue
0.863 0.137 0.000
Z99.1 Dependence on respirator
0.862 0.138 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.860 0.140 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.860 0.140 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.858 0.142 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.857 0.143 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
R79 Other abnormal findings of blood chemistry
0.851 0.149 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.851 0.149 0.000
S90-S99 Injuries to the ankle and foot
0.849 0.151 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.848 0.152 0.000
R94 Abnormal results of function studies
0.848 0.152 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.847 0.153 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.845 0.155 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.841 0.159 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.841 0.159 0.000
E10-E14 Diabetes mellitus
0.840 0.160 0.000
C34.9 Bronchus or lung, unspecified
0.839 0.161 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.838 0.162 0.000
I47 Paroxysmal tachycardia
0.838 0.162 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.836 0.164 0.000
N17 Acute renal failure
0.834 0.166 0.000
G93 Other disorders of brain
0.832 0.168 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.832 0.168 0.000
Z47 Other orthopaedic follow-up care
0.831 0.169 0.000
I46 Cardiac arrest
0.829 0.171 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.827 0.173 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.823 0.177 0.000
C64-C68 Malignant neoplasms of urinary tract
0.820 0.180 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.820 0.180 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.818 0.182 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.817 0.183 0.000
W00-W19 Falls
0.817 0.183 0.000
A49.0 Staphylococcal infection, unspecified
0.816 0.184 0.000
C34.3 Lower lobe, bronchus or lung
0.815 0.185 0.000
I26 Pulmonary embolism
0.815 0.185 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.815 0.185 0.000
I50.1 Left ventricular failure
0.812 0.188 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.811 0.189 0.000
L03.0 Cellulitis of finger and toe
0.810 0.190 0.000
J98 Other respiratory disorders
0.810 0.190 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.810 0.190 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.809 0.191 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.809 0.191 0.000
M86-M90 Other osteopathies
0.808 0.192 0.000
S20-S29 Injuries to the thorax
0.807 0.193 0.000
C18 Malignant neoplasm of colon
0.807 0.193 0.000
N17.9 Acute renal failure, unspecified
0.806 0.194 0.000
L29 Pruritus
0.804 0.196 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.804 0.196 0.000
X50-X57 Overexertion, travel and privation
0.804 0.196 0.000
E87.2 Acidosis
0.804 0.196 0.000
J42 Unspecified chronic bronchitis
0.804 0.196 0.000
B35-B49 Mycoses
0.804 0.196 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.803 0.197 0.000
M21 Other acquired deformities of limbs
0.803 0.197 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.801 0.199 0.000
G62 Other polyneuropathies
0.799 0.201 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.798 0.202 0.000
E14 Unspecified diabetes mellitus
0.797 0.203 0.000
E87.5 Hyperkalaemia
0.797 0.203 0.000
W20-W49 Exposure to inanimate mechanical forces
0.796 0.204 0.000
S82 Fracture of lower leg, including ankle
0.796 0.204 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.796 0.204 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.794 0.206 0.000
N18 Chronic renal failure
0.794 0.206 0.000
F10.0 Acute intoxication
0.794 0.206 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.793 0.207 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.793 0.207 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.793 0.207 0.000
J47 Bronchiectasis
0.793 0.207 0.000
I50.9 Heart failure, unspecified
0.792 0.208 0.000
Z46.6 Fitting and adjustment of urinary device
0.792 0.208 0.000
L27 Dermatitis due to substances taken internally
0.792 0.208 0.000
N41 Inflammatory diseases of prostate
0.792 0.208 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.792 0.208 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.791 0.209 0.000
E87.7 Fluid overload
0.790 0.210 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.790 0.210 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
G20-G26 Extrapyramidal and movement disorders
0.786 0.214 0.000
J20-J22 Other acute lower respiratory infections
0.786 0.214 0.000
M20 Acquired deformities of fingers and toes
0.786 0.214 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.785 0.215 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.784 0.216 0.000
Z50 Care involving use of rehabilitation procedures
0.784 0.216 0.000
R94.5 Abnormal results of liver function studies
0.783 0.217 0.000
E83 Disorders of mineral metabolism
0.783 0.217 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.782 0.218 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
C85.1 B-cell lymphoma, unspecified
0.781 0.219 0.000
Y40 Systemic antibiotics
0.780 0.220 0.000
N48 Other disorders of penis
0.779 0.221 0.000
I74 Arterial embolism and thrombosis
0.778 0.222 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.778 0.222 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
Z99.3 Dependence on wheelchair
0.777 0.223 0.000
J43 Emphysema
0.776 0.224 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.776 0.224 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.776 0.224 0.000
R30-R39 Symptoms and signs involving the urinary system
0.775 0.225 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.773 0.227 0.000
J00 Acute nasopharyngitis [common cold]
0.773 0.227 0.000
J98.1 Pulmonary collapse
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
Z53.0 Procedure not carried out because of contraindication
0.772 0.228 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.771 0.229 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.770 0.230 0.000
L05 Pilonidal cyst
0.768 0.232 0.000
J60-J70 Lung diseases due to external agents
0.768 0.232 0.000
E14.9 Without complications
0.767 0.233 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.766 0.233 0.000
I45 Other conduction disorders
0.766 0.234 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.765 0.235 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.765 0.235 0.000
R33 Retention of urine
0.764 0.236 0.000
S61 Open wound of wrist and hand
0.764 0.236 0.000
J30-J39 Other diseases of upper respiratory tract
0.764 0.236 0.000
A49.8 Other bacterial infections of unspecified site
0.764 0.236 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.762 0.238 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.762 0.238 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.759 0.241 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.757 0.243 0.000
C92 Myeloid leukaemia
0.754 0.246 0.000
M54 Dorsalgia
0.754 0.246 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.754 0.246 0.000
M67 Other disorders of synovium and tendon
0.754 0.246 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.753 0.247 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.753 0.247 0.000
Z93.3 Colostomy status
0.752 0.248 0.000
Z89 Acquired absence of limb
0.752 0.248 0.000
Z47.8 Other specified orthopaedic follow-up care
0.751 0.249 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.751 0.249 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.750 0.250 0.000
M25 Other joint disorders, not elsewhere classified
0.750 0.250 0.000
C67 Malignant neoplasm of bladder
0.749 0.251 0.000
M50 Cervical disk disorders
0.747 0.253 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.747 0.253 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.746 0.254 0.000
R73 Elevated blood glucose level
0.746 0.254 0.000
C25 Malignant neoplasm of pancreas
0.746 0.254 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.745 0.255 0.000
Z86.7 Personal history of diseases of the circulatory system
0.745 0.255 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.743 0.257 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.742 0.258 0.000
S10-S19 Injuries to the neck
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.740 0.260 0.000
J90 Pleural effusion, not elsewhere classified
0.740 0.260 0.000
E20-E35 Disorders of other endocrine glands
0.740 0.260 0.000
Z85 Personal history of malignant neoplasm
0.737 0.263 0.000
I51.9 Heart disease, unspecified
0.737 0.263 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.736 0.264 0.000
D50-D53 Nutritional anaemias
0.734 0.265 0.000
Z99.8 Dependence on other enabling machines and devices
0.733 0.267 0.000
M65.8 Other synovitis and tenosynovitis
0.731 0.268 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.730 0.270 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.729 0.271 0.000
S99 Other and unspecified injuries of ankle and foot
0.728 0.271 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.728 0.272 0.000
I05 Rheumatic mitral valve diseases
0.728 0.272 0.000
Z90.7 Acquired absence of genital organ(s)
0.728 0.272 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.727 0.273 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.726 0.274 0.000
V10-V19 Pedal cyclist injured in transport accident
0.726 0.274 0.000
Y84.8 Other medical procedures
0.725 0.275 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.724 0.276 0.000
I49 Other cardiac arrhythmias
0.724 0.276 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
E88 Other metabolic disorders
0.723 0.277 0.000
S60 Superficial injury of wrist and hand
0.722 0.278 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.722 0.278 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.721 0.279 0.000
Z92.3 Personal history of irradiation
0.721 0.279 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.721 0.279 0.000
Y43 Primarily systemic agents
0.721 0.279 0.000
C79 Secondary malignant neoplasm of other sites
0.720 0.280 0.000
Z41 Procedures for purposes other than remedying health state
0.719 0.281 0.000
G61 Inflammatory polyneuropathy
0.719 0.281 0.000
Y86 Sequelae of other accidents
0.719 0.281 0.000
J84 Other interstitial pulmonary diseases
0.719 0.281 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.719 0.281 0.000
G62.9 Polyneuropathy, unspecified
0.718 0.282 0.000
J94 Other pleural conditions
0.718 0.282 0.000
Z87.8 Personal history of other specified conditions
0.718 0.282 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.718 0.282 0.000
Z90.2 Acquired absence of lung [part of]
0.718 0.282 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.717 0.283 0.000
C81 Hodgkin's disease
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
Z97 Presence of other devices
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.716 0.284 0.000
N00-N08 Glomerular diseases
0.715 0.285 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.714 0.286 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.713 0.287 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.713 0.287 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.713 0.287 0.000
Y52 Agents primarily affecting the cardiovascular system
0.712 0.288 0.000
L04 Acute lymphadenitis
0.712 0.288 0.000
L01 Impetigo
0.712 0.288 0.000
L00 Staphylococcal scalded skin syndrome
0.712 0.288 0.000
T81.9 Unspecified complication of procedure
0.711 0.288 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.711 0.288 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.711 0.288 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.711 0.288 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.711 0.288 0.000
A48 Other bacterial diseases, not elsewhere classified
0.711 0.289 0.000
A44 Bartonellosis
0.711 0.289 0.000
A43 Nocardiosis
0.711 0.289 0.000
A42 Actinomycosis
0.711 0.289 0.000
A40 Streptococcal septicaemia
0.711 0.289 0.000
A39 Meningococcal infection
0.711 0.289 0.000
A37 Whooping cough
0.711 0.289 0.000
A36 Diphtheria
0.711 0.289 0.000
A32 Listeriosis
0.711 0.289 0.000
A31 Infection due to other mycobacteria
0.711 0.289 0.000
A30 Leprosy [Hansen's disease]
0.711 0.289 0.000
A46 Erysipelas
0.711 0.289 0.000
A38 Scarlet fever
0.711 0.289 0.000
A35 Other tetanus
0.711 0.289 0.000
A34 Obstetrical tetanus
0.711 0.289 0.000
A33 Tetanus neonatorum
0.711 0.289 0.000
J93 Pneumothorax
0.711 0.289 0.000
S69 Other and unspecified injuries of wrist and hand
0.711 0.289 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.710 0.290 0.000
R50-R69 General symptoms and signs
0.710 0.290 0.000
T66-T78 Other and unspecified effects of external causes
0.709 0.290 0.000
M31 Other necrotising vasculopathies
0.709 0.291 0.000
I08 Multiple valve diseases
0.709 0.291 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.708 0.292 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.708 0.292 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.708 0.292 0.000
I38 Endocarditis, valve unspecified
0.708 0.292 0.000
G91 Hydrocephalus
0.707 0.293 0.000
S83.2 Tear of meniscus, current
0.707 0.293 0.000
C83.3 Large cell (diffuse)
0.705 0.295 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
L03.9 Cellulitis, unspecified
0.705 0.295 0.000
Z95.3 Presence of xenogenic heart valve
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.297 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.703 0.297 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.297 0.000
I51.5 Myocardial degeneration
0.703 0.297 0.000
I51.4 Myocarditis, unspecified
0.703 0.297 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.703 0.297 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.703 0.297 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.703 0.297 0.000
I51.0 Cardiac septal defect, acquired
0.703 0.297 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.702 0.297 0.000
Z53.9 Procedure not carried out, unspecified reason
0.702 0.298 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.702 0.298 0.000
J32 Chronic sinusitis
0.702 0.298 0.000
E85 Amyloidosis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
J04 Acute laryngitis and tracheitis
0.700 0.300 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
Z93.0 Tracheostomy status
0.700 0.300 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.700 0.300 0.000
I27.9 Pulmonary heart disease, unspecified
0.699 0.301 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.699 0.301 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
C95 Leukaemia of unspecified cell type
0.698 0.302 0.000
C94 Other leukaemias of specified cell type
0.698 0.302 0.000
C93 Monocytic leukaemia
0.698 0.302 0.000
C88 Malignant immunoproliferative diseases
0.698 0.302 0.000
C86 Other specified types of T/NK-cell lymphoma
0.698 0.302 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.698 0.302 0.000
G95 Other diseases of spinal cord
0.698 0.302 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.698 0.302 0.000
F60-F69 Disorders of adult personality and behaviour
0.698 0.302 0.000
G96 Other disorders of central nervous system
0.698 0.302 0.000
M45-M49 Spondylopathies
0.697 0.303 0.000
M24 Other specific joint derangements
0.697 0.303 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.697 0.303 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.696 0.304 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.696 0.304 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.696 0.304 0.000
I51.7 Cardiomegaly
0.696 0.304 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.696 0.304 0.000
E87.4 Mixed disorder of acid-base balance
0.696 0.304 0.000
E87.3 Alkalosis
0.696 0.304 0.000
Z54 Convalescence
0.696 0.304 0.000
Z44 Fitting and adjustment of external prosthetic device
0.696 0.304 0.000
F10.2 Dependence syndrome
0.696 0.304 0.000
A41.8 Other specified septicaemia
0.695 0.305 0.000
A41.4 Septicaemia due to anaerobes
0.695 0.305 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.695 0.305 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.695 0.305 0.000
L29.9 Pruritus, unspecified
0.695 0.305 0.000
J41 Simple and mucopurulent chronic bronchitis
0.695 0.305 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.694 0.305 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.694 0.305 0.000
C21 Malignant neoplasm of anus and anal canal
0.694 0.305 0.000
C17 Malignant neoplasm of small intestine
0.694 0.305 0.000
C23 Malignant neoplasm of gallbladder
0.694 0.305 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.694 0.306 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.694 0.306 0.000
E16 Other disorders of pancreatic internal secretion
0.694 0.306 0.000
R79.0 Abnormal level of blood mineral
0.693 0.307 0.000
L03.8 Cellulitis of other sites
0.692 0.308 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.692 0.308 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.691 0.309 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.691 0.309 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.690 0.310 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.689 0.311 0.000
I28 Other diseases of pulmonary vessels
0.689 0.311 0.000
Z49 Care involving dialysis
0.688 0.312 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.688 0.312 0.000
E00-E07 Disorders of thyroid gland
0.688 0.312 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.687 0.313 0.000
G90 Disorders of autonomic nervous system
0.687 0.313 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.687 0.313 0.000
G92 Toxic encephalopathy
0.687 0.313 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.687 0.313 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.687 0.313 0.000
I46.0 Cardiac arrest with successful resuscitation
0.686 0.314 0.000
J33 Nasal polyp
0.686 0.314 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.685 0.314 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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