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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114414817
log Bayes Factor = 16.8696
Chromosome 5   position 144,809,230  (GRCh37) Explore rs114414817 on Ensembl!
Variant rs114414817 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.988 0.012 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.987 0.013 0.000
Z51 Other medical care
0.986 0.014 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.985 0.015 0.000
R50-R69 General symptoms and signs
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.980 0.020 0.000
Z50 Care involving use of rehabilitation procedures
0.979 0.021 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.978 0.022 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.976 0.024 0.000
O60-O75 Complications of labour and delivery
0.973 0.027 0.000
Chapter IX Diseases of the circulatory system
0.971 0.029 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.971 0.029 0.000
Z51.1 Chemotherapy session for neoplasm
0.969 0.031 0.000
M20-M25 Other joint disorders
0.962 0.038 0.000
K70-K77 Diseases of liver
0.960 0.040 0.000
Chapter I Certain infectious and parasitic diseases
0.959 0.041 0.000
G40 Epilepsy
0.956 0.044 0.000
R55 Syncope and collapse
0.947 0.053 0.000
M65-M68 Disorders of synovium and tendon
0.946 0.054 0.000
R50 Fever of unknown origin
0.942 0.058 0.000
G47 Sleep disorders
0.941 0.059 0.000
K83 Other diseases of biliary tract
0.940 0.060 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.938 0.062 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.932 0.068 0.000
Y43 Primarily systemic agents
0.932 0.068 0.000
Z42 Follow-up care involving plastic surgery
0.928 0.072 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.924 0.076 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.921 0.079 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.919 0.081 0.000
G43 Migraine
0.916 0.084 0.000
M23 Internal derangement of knee
0.913 0.087 0.000
Z51.3 Blood transfusion without reported diagnosis
0.913 0.087 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.911 0.089 0.000
R50.9 Fever, unspecified
0.910 0.090 0.000
Chapter X Diseases of the respiratory system
0.902 0.098 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.898 0.102 0.000
Z36 Antenatal screening
0.898 0.102 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.898 0.102 0.000
G47.3 Sleep apnoea
0.898 0.102 0.000
K83.1 Obstruction of bile duct
0.897 0.103 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.897 0.103 0.000
A00-A09 Intestinal infectious diseases
0.897 0.103 0.000
K76 Other diseases of liver
0.893 0.107 0.000
C79 Secondary malignant neoplasm of other sites
0.893 0.107 0.000
O36 Maternal care for other known or suspected foetal problems
0.889 0.111 0.000
R68 Other general symptoms and signs
0.889 0.111 0.000
M45-M49 Spondylopathies
0.888 0.112 0.000
D00-D09 In situ neoplasms
0.884 0.116 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.882 0.118 0.000
M25 Other joint disorders, not elsewhere classified
0.877 0.123 0.000
C51-C58 Malignant neoplasms of female genital organs
0.875 0.125 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.875 0.125 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.872 0.128 0.000
M65 Synovitis and tenosynovitis
0.867 0.133 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.865 0.135 0.000
M23.3 Other meniscus derangements
0.865 0.135 0.000
O48 Prolonged pregnancy
0.864 0.136 0.000
G90-G99 Other disorders of the nervous system
0.863 0.137 0.000
Z50.5 Speech therapy
0.861 0.139 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.861 0.139 0.000
G43.9 Migraine, unspecified
0.858 0.142 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.858 0.142 0.000
J90-J94 Other diseases of pleura
0.858 0.142 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.858 0.142 0.000
O63 Long labour
0.852 0.148 0.000
D50-D53 Nutritional anaemias
0.850 0.150 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.849 0.151 0.000
Y43.3 Other antineoplastic drugs
0.849 0.151 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.845 0.155 0.000
I84 Haemorrhoids
0.840 0.160 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.840 0.160 0.000
E70-E90 Metabolic disorders
0.837 0.163 0.000
M50-M54 Other dorsopathies
0.836 0.164 0.000
Chapter XIV Diseases of the genitourinary system
0.835 0.165 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.834 0.166 0.000
G40.9 Epilepsy, unspecified
0.834 0.166 0.000
K86 Other diseases of pancreas
0.831 0.169 0.000
R52 Pain, not elsewhere classified
0.830 0.170 0.000
K80 Cholelithiasis
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.828 0.172 0.000
Z36.9 Antenatal screening, unspecified
0.828 0.172 0.000
K82 Other diseases of gallbladder
0.828 0.172 0.000
J95-J99 Other diseases of the respiratory system
0.826 0.174 0.000
K35-K38 Diseases of appendix
0.825 0.175 0.000
O62 Abnormalities of forces of labour
0.825 0.175 0.000
Z50.1 Other physical therapy
0.824 0.176 0.000
C83.3 Large cell (diffuse)
0.823 0.177 0.000
R68.8 Other specified general symptoms and signs
0.822 0.178 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.821 0.179 0.000
Y43.4 Immunosuppressive agents
0.821 0.179 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.819 0.180 0.000
I60-I69 Cerebrovascular diseases
0.819 0.181 0.000
T66-T78 Other and unspecified effects of external causes
0.818 0.182 0.000
M67 Other disorders of synovium and tendon
0.818 0.182 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.816 0.184 0.000
Z35 Supervision of high-risk pregnancy
0.816 0.184 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.815 0.185 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.814 0.186 0.000
I05-I09 Chronic rheumatic heart diseases
0.813 0.187 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.813 0.187 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.808 0.192 0.000
M40-M43 Deforming dorsopathies
0.808 0.192 0.000
N20-N23 Urolithiasis
0.807 0.193 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.807 0.193 0.000
J90 Pleural effusion, not elsewhere classified
0.807 0.193 0.000
K74 Fibrosis and cirrhosis of liver
0.807 0.193 0.000
C77.2 Intra-abdominal lymph nodes
0.806 0.194 0.000
C78.2 Secondary malignant neoplasm of pleura
0.806 0.194 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.804 0.196 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.804 0.196 0.000
K76.6 Portal hypertension
0.802 0.198 0.000
N60-N64 Disorders of breast
0.801 0.199 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.800 0.200 0.000
Z49 Care involving dialysis
0.799 0.201 0.000
D73 Diseases of spleen
0.798 0.202 0.000
R53 Malaise and fatigue
0.798 0.202 0.000
B15-B19 Viral hepatitis
0.797 0.203 0.000
Y52 Agents primarily affecting the cardiovascular system
0.796 0.204 0.000
G44 Other headache syndromes
0.795 0.205 0.000
R25 Abnormal involuntary movements
0.791 0.209 0.000
D60-D64 Aplastic and other anaemias
0.790 0.210 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.790 0.210 0.000
D70 Agranulocytosis
0.787 0.212 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.786 0.214 0.000
M15-M19 Arthrosis
0.786 0.214 0.000
E83 Disorders of mineral metabolism
0.786 0.214 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.786 0.214 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.784 0.216 0.000
Z51.0 Radiotherapy session
0.784 0.216 0.000
S80-S89 Injuries to the knee and lower leg
0.783 0.217 0.000
B35-B49 Mycoses
0.783 0.217 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.782 0.218 0.000
Z90.1 Acquired absence of breast(s)
0.780 0.220 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.779 0.221 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.776 0.224 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.776 0.224 0.000
D80-D89 Certain disorders involving the immune mechanism
0.776 0.224 0.000
O72 Postpartum haemorrhage
0.776 0.224 0.000
D03 Melanoma in situ
0.774 0.225 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.772 0.228 0.000
O66 Other obstructed labour
0.771 0.229 0.000
K72 Hepatic failure, not elsewhere classified
0.771 0.229 0.000
R59 Enlarged lymph nodes
0.770 0.230 0.000
M70-M79 Other soft tissue disorders
0.769 0.231 0.000
C80 Malignant neoplasm without specification of site
0.769 0.231 0.000
M25.5 Pain in joint
0.768 0.232 0.000
Y40 Systemic antibiotics
0.767 0.233 0.000
C64-C68 Malignant neoplasms of urinary tract
0.767 0.233 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.766 0.234 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.766 0.234 0.000
I63 Cerebral infarction
0.765 0.235 0.000
R56 Convulsions, not elsewhere classified
0.764 0.236 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.763 0.237 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.763 0.237 0.000
K85 Acute pancreatitis
0.763 0.237 0.000
G70-G73 Diseases of myoneural junction and muscle
0.762 0.238 0.000
Z94 Transplanted organ and tissue status
0.761 0.239 0.000
O47 False labour
0.760 0.240 0.000
C54 Malignant neoplasm of corpus uteri
0.759 0.241 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.759 0.241 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.759 0.241 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.759 0.241 0.000
Z90.5 Acquired absence of kidney
0.757 0.243 0.000
M47 Spondylosis
0.755 0.245 0.000
N20 Calculus of kidney and ureter
0.754 0.246 0.000
K83.8 Other specified diseases of biliary tract
0.754 0.246 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.753 0.247 0.000
T81 Complications of procedures, not elsewhere classified
0.753 0.247 0.000
Z99.8 Dependence on other enabling machines and devices
0.752 0.248 0.000
Z54 Convalescence
0.752 0.248 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.751 0.248 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.751 0.248 0.000
M91-M94 Chondropathies
0.751 0.249 0.000
I81 Portal vein thrombosis
0.750 0.250 0.000
J00-J06 Acute upper respiratory infections
0.748 0.251 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.748 0.252 0.000
J98 Other respiratory disorders
0.748 0.252 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.747 0.253 0.000
S00-S09 Injuries to the head
0.746 0.254 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.745 0.255 0.000
Z51.5 Palliative care
0.745 0.255 0.000
Z36.8 Other antenatal screening
0.745 0.255 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
O63.1 Prolonged second stage (of labour)
0.744 0.256 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.744 0.256 0.000
O42 Premature rupture of membranes
0.744 0.256 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.743 0.257 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.742 0.258 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.742 0.258 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.741 0.258 0.000
R52.2 Other chronic pain
0.741 0.259 0.000
N60 Benign mammary dysplasia
0.741 0.259 0.000
G93 Other disorders of brain
0.741 0.259 0.000
O36.8 Maternal care for other specified foetal problems
0.741 0.259 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.740 0.260 0.000
Z48 Other surgical follow-up care
0.740 0.260 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.739 0.261 0.000
Z34 Supervision of normal pregnancy
0.739 0.261 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.738 0.262 0.000
D50 Iron deficiency anaemia
0.736 0.263 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.736 0.264 0.000
I86 Varicose veins of other sites
0.735 0.265 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.733 0.267 0.000
Y95 Nosocomial condition
0.732 0.268 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.731 0.269 0.000
K70 Alcoholic liver disease
0.730 0.270 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.729 0.271 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.729 0.271 0.000
M19 Other arthrosis
0.728 0.272 0.000
Z92 Personal history of medical treatment
0.727 0.273 0.000
C50-C50 Malignant neoplasm of breast
0.726 0.274 0.000
M67.8 Other specified disorders of synovium and tendon
0.726 0.274 0.000
V10-V19 Pedal cyclist injured in transport accident
0.726 0.274 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.724 0.276 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.724 0.276 0.000
W00-W19 Falls
0.723 0.277 0.000
N62 Hypertrophy of breast
0.722 0.278 0.000
R54 Senility
0.721 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.721 0.279 0.000
K50-K52 Noninfective enteritis and colitis
0.720 0.280 0.000
K75 Other inflammatory liver diseases
0.720 0.280 0.000
Z50.8 Care involving use of rehabilitation procedures
0.720 0.280 0.000
O36.6 Maternal care for excessive foetal growth
0.719 0.280 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.719 0.281 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.719 0.281 0.000
E83.5 Disorders of calcium metabolism
0.719 0.281 0.000
R61 Hyperhidrosis
0.719 0.281 0.000
O62.2 Other uterine inertia
0.719 0.281 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.719 0.281 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.719 0.281 0.000
M48 Other spondylopathies
0.719 0.281 0.000
C79.6 Secondary malignant neoplasm of ovary
0.718 0.282 0.000
C77.3 Axillary and upper limb lymph nodes
0.717 0.283 0.000
D73.0 Hyposplenism
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.717 0.283 0.000
Z85 Personal history of malignant neoplasm
0.717 0.283 0.000
Z47 Other orthopaedic follow-up care
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
Z52 Donors of organs and tissues
0.715 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.284 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.285 0.000
G41 Status epilepticus
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
C77.1 Intrathoracic lymph nodes
0.714 0.286 0.000
K35 Acute appendicitis
0.714 0.286 0.000
I84.2 Internal haemorrhoids without complication
0.714 0.286 0.000
I95 Hypotension
0.714 0.286 0.000
M51 Other intervertebral disk disorders
0.713 0.287 0.000
G20-G26 Extrapyramidal and movement disorders
0.713 0.287 0.000
M31 Other necrotising vasculopathies
0.712 0.288 0.000
E20-E35 Disorders of other endocrine glands
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
B95-B98 Bacterial, viral and other infectious agents
0.710 0.290 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.710 0.290 0.000
I10-I15 Hypertensive diseases
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
Z90.7 Acquired absence of genital organ(s)
0.710 0.290 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
Y44 Agents primarily affecting blood constituents
0.710 0.290 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.709 0.291 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.709 0.291 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.708 0.292 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.707 0.293 0.000
B25-B34 Other viral diseases
0.707 0.293 0.000
Z51.9 Medical care, unspecified
0.707 0.293 0.000
Z51.6 Desensitisation to allergens
0.707 0.293 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
J60-J70 Lung diseases due to external agents
0.706 0.294 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.705 0.295 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.705 0.295 0.000
R62 Lack of expected normal physiological development
0.705 0.295 0.000
R57 Shock, not elsewhere classified
0.705 0.295 0.000
R64 Cachexia
0.705 0.295 0.000
R58 Haemorrhage, not elsewhere classified
0.705 0.295 0.000
T78 Adverse effects, not elsewhere classified
0.705 0.295 0.000
I85 Oesophageal varices
0.704 0.296 0.000
R45 Symptoms and signs involving emotional state
0.703 0.297 0.000
R94 Abnormal results of function studies
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.703 0.297 0.000
Y58 Bacterial vaccines
0.703 0.297 0.000
Y57 Other and unspecified drugs and medicaments
0.703 0.297 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.703 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.703 0.297 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.703 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.703 0.297 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
Y48 Anaesthetics and therapeutic gases
0.703 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.703 0.297 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.703 0.297 0.000
Z82.3 Family history of stroke
0.702 0.298 0.000
Z50.6 Orthoptic training
0.702 0.298 0.000
Z50.3 Drug rehabilitation
0.702 0.298 0.000
Z50.2 Alcohol rehabilitation
0.702 0.298 0.000
R21 Rash and other nonspecific skin eruption
0.702 0.298 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.701 0.299 0.000
O30 Multiple gestation
0.701 0.299 0.000
M25.8 Other specified joint disorders
0.701 0.299 0.000
G47.9 Sleep disorder, unspecified
0.700 0.300 0.000
K83.0 Cholangitis
0.700 0.300 0.000
R50.0 Fever with chills
0.700 0.300 0.000
R25.2 Cramp and spasm
0.700 0.300 0.000
I82 Other venous embolism and thrombosis
0.700 0.300 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
T33-T35 Frostbite
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.700 0.300 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.700 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.300 0.000
T00-T07 Injuries involving multiple body regions
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.700 0.300 0.000
D06 Carcinoma in situ of cervix uteri
0.698 0.302 0.000
M80-M85 Disorders of bone density and structure
0.698 0.302 0.000
O74 Complications of anaesthesia during labour and delivery
0.698 0.302 0.000
O73 Retained placenta and membranes, without haemorrhage
0.698 0.302 0.000
O71 Other obstetric trauma
0.698 0.302 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.698 0.302 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.698 0.302 0.000
O61 Failed induction of labour
0.698 0.302 0.000
O60 Preterm delivery
0.698 0.302 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.698 0.302 0.000
M19.9 Arthrosis, unspecified
0.698 0.302 0.000
N23 Unspecified renal colic
0.697 0.303 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.697 0.303 0.000
K65-K67 Diseases of peritoneum
0.697 0.303 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.697 0.303 0.000
I00-I02 Acute rheumatic fever
0.696 0.303 0.000
O45 Premature separation of placenta [abruptio placentae]
0.696 0.304 0.000
O44 Placenta praevia
0.696 0.304 0.000
O43 Placental disorders
0.696 0.304 0.000
O41 Other disorders of amniotic fluid and membranes
0.696 0.304 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.696 0.304 0.000
O33 Maternal care for known or suspected disproportion
0.696 0.304 0.000
O31 Complications specific to multiple gestation
0.696 0.304 0.000
O40 Polyhydramnios
0.696 0.304 0.000
I84.8 Unspecified haemorrhoids with other complications
0.696 0.304 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
K04 Diseases of pulp and periapical tissues
0.695 0.305 0.000
I08 Multiple valve diseases
0.695 0.305 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.695 0.305 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.695 0.305 0.000
K86.8 Other specified diseases of pancreas
0.695 0.305 0.000
K74.3 Primary biliary cirrhosis
0.694 0.306 0.000
S20-S29 Injuries to the thorax
0.694 0.306 0.000
I84.3 External thrombosed haemorrhoids
0.694 0.306 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.693 0.307 0.000
Z35.5 Supervision of elderly primigravida
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.691 0.309 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M34 Systemic sclerosis
0.690 0.310 0.000
M33 Dermatopolymyositis
0.690 0.310 0.000
M32 Systemic lupus erythematosus
0.690 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.310 0.000
M22 Disorders of patella
0.690 0.310 0.000
M21 Other acquired deformities of limbs
0.690 0.310 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.689 0.311 0.000
K77 Liver disorders in diseases classified elsewhere
0.688 0.312 0.000
K73 Chronic hepatitis, not elsewhere classified
0.688 0.312 0.000
K71 Toxic liver disease
0.688 0.312 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.688 0.312 0.000
X60-X84 Intentional self-harm
0.688 0.312 0.000
Z50.0 Cardiac rehabilitation
0.688 0.312 0.000
B99-B99 Other infectious diseases
0.687 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.312 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.312 0.000
B65-B83 Helminthiases
0.687 0.312 0.000
B50-B64 Protozoal diseases
0.687 0.312 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.687 0.312 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.312 0.000
A80-A89 Viral infections of the central nervous system
0.687 0.312 0.000
A75-A79 Rickettsioses
0.687 0.312 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.312 0.000
A65-A69 Other spirochaetal diseases
0.687 0.312 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.687 0.312 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.312 0.000
A15-A19 Tuberculosis
0.687 0.312 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.687 0.313 0.000
M25.7 Osteophyte
0.687 0.313 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.687 0.313 0.000
C79.2 Secondary malignant neoplasm of skin
0.686 0.314 0.000
S01 Open wound of head
0.686 0.314 0.000
A08 Viral and other specified intestinal infections
0.686 0.314 0.000
M25.56 Pain in joint (Lower leg)
0.685 0.315 0.000
G40.8 Other epilepsy
0.685 0.315 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.685 0.315 0.000
G40.5 Special epileptic syndromes
0.685 0.315 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.685 0.315 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.685 0.315 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.685 0.315 0.000
I63.9 Cerebral infarction, unspecified
0.684 0.316 0.000
G96 Other disorders of central nervous system
0.684 0.316 0.000
M75 Shoulder lesions
0.684 0.316 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.683 0.317 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.681 0.319 0.000
Z87 Personal history of other diseases and conditions
0.681 0.319 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.681 0.319 0.000
B18 Chronic viral hepatitis
0.680 0.320 0.000
J98.4 Other disorders of lung
0.680 0.320 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.678 0.322 0.000
M66 Spontaneous rupture of synovium and tendon
0.678 0.322 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.678 0.322 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.677 0.322 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.677 0.323 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.677 0.323 0.000
M65.3 Trigger finger
0.676 0.323 0.000
C54.1 Endometrium
0.676 0.324 0.000
J92 Pleural plaque
0.676 0.324 0.000
D68 Other coagulation defects
0.676 0.324 0.000
R50.8 Other specified fever
0.675 0.324 0.000
R50.2 Drug-induced fever
0.675 0.324 0.000
R50.1 Persistent fever
0.675 0.324 0.000
G47.8 Other sleep disorders
0.675 0.325 0.000
G47.4 Narcolepsy and cataplexy
0.675 0.325 0.000
G47.2 Disorders of the sleep-wake schedule
0.675 0.325 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.675 0.325 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.675 0.325 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.675 0.325 0.000
C56 Malignant neoplasm of ovary
0.675 0.325 0.000
Z40 Prophylactic surgery
0.675 0.325 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.675 0.325 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.674 0.326 0.000
K83.9 Disease of biliary tract, unspecified
0.674 0.326 0.000
K83.5 Biliary cyst
0.674 0.326 0.000
K83.4 Spasm of sphincter of Oddi
0.674 0.326 0.000
K83.3 Fistula of bile duct
0.674 0.326 0.000
K83.2 Perforation of bile duct
0.674 0.326 0.000
M47.8 Other spondylosis
0.674 0.326 0.000
C77.5 Intrapelvic lymph nodes
0.674 0.326 0.000
J09-J18 Influenza and pneumonia
0.673 0.327 0.000
Z38 Liveborn infants according to place of birth
0.672 0.327 0.000
Z32 Pregnancy examination and test
0.672 0.327 0.000
Z31 Procreative management
0.672 0.327 0.000
Z33 Pregnant state, incidental
0.672 0.327 0.000
O00-O08 Pregnancy with abortive outcome
0.672 0.328 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.672 0.328 0.000
O36.9 Maternal care for foetal problem, unspecified
0.671 0.329 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.671 0.329 0.000
D50.8 Other iron deficiency anaemias
0.671 0.329 0.000
M46 Other inflammatory spondylopathies
0.670 0.330 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.670 0.330 0.000
K82.8 Other specified diseases of gallbladder
0.669 0.331 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.668 0.331 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.668 0.331 0.000
C91 Lymphoid leukaemia
0.668 0.332 0.000
Y43.9 Primarily systemic agent, unspecified
0.668 0.332 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.668 0.332 0.000
Y43.6 Enzymes, not elsewhere classified
0.668 0.332 0.000
Y43.5 Acidifying and alkalising agents
0.668 0.332 0.000
Y43.2 Antineoplastic natural products
0.668 0.332 0.000
Y43.1 Antineoplastic antimetabolites
0.668 0.332 0.000
Y43.0 Antiallergic and antiemetic drugs
0.668 0.332 0.000
K82.4 Cholesterolosis of gallbladder
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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