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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114584378
log Bayes Factor = 15.7188
Chromosome 2   position 193,298,755  (GRCh37) Explore rs114584378 on Ensembl!
Variant rs114584378 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
J40-J47 Chronic lower respiratory diseases
0.991 0.009 0.000
Chapter XXI Factors influencing health status and contact with health services
0.985 0.015 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.984 0.016 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.980 0.020 0.000
I51 Complications and ill-defined descriptions of heart disease
0.970 0.030 0.000
B95-B98 Bacterial, viral and other infectious agents
0.970 0.030 0.000
I44 Atrioventricular and left bundle-branch block
0.970 0.030 0.000
J45 Asthma
0.967 0.033 0.000
Z51 Other medical care
0.961 0.039 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.960 0.040 0.000
J45.9 Asthma, unspecified
0.958 0.042 0.000
Chapter VI Diseases of the nervous system
0.956 0.044 0.000
M25 Other joint disorders, not elsewhere classified
0.953 0.047 0.000
E20-E35 Disorders of other endocrine glands
0.948 0.052 0.000
Z50 Care involving use of rehabilitation procedures
0.943 0.057 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.941 0.059 0.000
M05-M14 Inflammatory polyarthropathies
0.934 0.066 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.934 0.066 0.000
E10-E14 Diabetes mellitus
0.933 0.067 0.000
M20 Acquired deformities of fingers and toes
0.931 0.069 0.000
Z51.5 Palliative care
0.930 0.070 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.928 0.072 0.000
I50 Heart failure
0.923 0.077 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.920 0.080 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.918 0.082 0.000
I51.7 Cardiomegaly
0.918 0.082 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.911 0.089 0.000
M45-M49 Spondylopathies
0.907 0.093 0.000
M70-M79 Other soft tissue disorders
0.906 0.094 0.000
J09-J18 Influenza and pneumonia
0.906 0.094 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.905 0.095 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.904 0.096 0.000
M50-M54 Other dorsopathies
0.902 0.098 0.000
I44.2 Atrioventricular block, complete
0.901 0.099 0.000
E70-E90 Metabolic disorders
0.901 0.099 0.000
E65-E68 Obesity and other hyperalimentation
0.900 0.100 0.000
I10-I15 Hypertensive diseases
0.897 0.103 0.000
I44.7 Left bundle-branch block, unspecified
0.893 0.107 0.000
L08 Other local infections of skin and subcutaneous tissue
0.892 0.108 0.000
Chapter XIV Diseases of the genitourinary system
0.890 0.110 0.000
N17-N19 Renal failure
0.888 0.112 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.884 0.116 0.000
M65-M68 Disorders of synovium and tendon
0.883 0.117 0.000
J44 Other chronic obstructive pulmonary disease
0.882 0.118 0.000
N18 Chronic renal failure
0.878 0.122 0.000
E50-E64 Other nutritional deficiencies
0.873 0.127 0.000
I35 Nonrheumatic aortic valve disorders
0.871 0.129 0.000
M35 Other systemic involvement of connective tissue
0.871 0.129 0.000
S90-S99 Injuries to the ankle and foot
0.869 0.131 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.866 0.134 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.864 0.136 0.000
I12 Hypertensive renal disease
0.862 0.138 0.000
J42 Unspecified chronic bronchitis
0.858 0.142 0.000
S50-S59 Injuries to the elbow and forearm
0.857 0.143 0.000
Z51.3 Blood transfusion without reported diagnosis
0.855 0.145 0.000
G90-G99 Other disorders of the nervous system
0.855 0.145 0.000
Z45 Adjustment and management of implanted device
0.855 0.145 0.000
Z51.2 Other chemotherapy
0.854 0.146 0.000
A30-A49 Other bacterial diseases
0.851 0.149 0.000
I49 Other cardiac arrhythmias
0.851 0.149 0.000
M20.2 Hallux rigidus
0.848 0.152 0.000
M25.5 Pain in joint
0.846 0.154 0.000
E00-E07 Disorders of thyroid gland
0.845 0.155 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.844 0.156 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.842 0.158 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.841 0.159 0.000
I51.8 Other ill-defined heart diseases
0.840 0.160 0.000
M25.7 Osteophyte
0.839 0.161 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.838 0.162 0.000
L90 Atrophic disorders of skin
0.836 0.164 0.000
I30 Acute pericarditis
0.835 0.165 0.000
I12.0 Hypertensive renal disease with renal failure
0.835 0.165 0.000
I42 Cardiomyopathy
0.833 0.167 0.000
I50.1 Left ventricular failure
0.832 0.168 0.000
M13 Other arthritis
0.832 0.168 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.832 0.168 0.000
Z49 Care involving dialysis
0.831 0.169 0.000
I95 Hypotension
0.827 0.173 0.000
E10 Insulin-dependent diabetes mellitus
0.825 0.175 0.000
A00-A09 Intestinal infectious diseases
0.824 0.176 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.823 0.177 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.822 0.178 0.000
M54 Dorsalgia
0.819 0.181 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.818 0.182 0.000
N18.3 Chronic kidney disease, stage 3
0.817 0.183 0.000
M21 Other acquired deformities of limbs
0.817 0.183 0.000
E40-E46 Malnutrition
0.815 0.184 0.000
E14 Unspecified diabetes mellitus
0.810 0.190 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.808 0.192 0.000
M22 Disorders of patella
0.807 0.193 0.000
E86 Volume depletion
0.806 0.194 0.000
E22 Hyperfunction of pituitary gland
0.806 0.194 0.000
N17 Acute renal failure
0.805 0.195 0.000
L50-L54 Urticaria and erythema
0.804 0.196 0.000
Z50.5 Speech therapy
0.804 0.196 0.000
Z45.2 Adjustment and management of vascular access device
0.803 0.197 0.000
I74 Arterial embolism and thrombosis
0.797 0.203 0.000
T66-T78 Other and unspecified effects of external causes
0.795 0.205 0.000
Z60 Problems related to social environment
0.795 0.205 0.000
M48 Other spondylopathies
0.790 0.210 0.000
Z43 Attention to artificial openings
0.790 0.210 0.000
J60-J70 Lung diseases due to external agents
0.790 0.210 0.000
J18 Pneumonia, organism unspecified
0.788 0.212 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.787 0.213 0.000
D50-D53 Nutritional anaemias
0.786 0.214 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.785 0.215 0.000
M35.3 Polymyalgia rheumatica
0.785 0.215 0.000
M25.8 Other specified joint disorders
0.785 0.215 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.785 0.215 0.000
J43 Emphysema
0.785 0.215 0.000
E66 Obesity
0.784 0.216 0.000
I31 Other diseases of pericardium
0.784 0.216 0.000
M00-M03 Infectious arthropathies
0.782 0.217 0.000
Z51.0 Radiotherapy session
0.781 0.219 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.781 0.219 0.000
M25.57 Pain in joint (Ankle and foot)
0.780 0.220 0.000
I47 Paroxysmal tachycardia
0.777 0.223 0.000
L89 Decubitus ulcer
0.776 0.224 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.774 0.226 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.770 0.229 0.000
S92 Fracture of foot, except ankle
0.770 0.230 0.000
I95.9 Hypotension, unspecified
0.769 0.231 0.000
T93 Sequelae of injuries of lower limb
0.768 0.232 0.000
I35.1 Aortic (valve) insufficiency
0.765 0.235 0.000
G56 Mononeuropathies of upper limb
0.765 0.235 0.000
J40 Bronchitis, not specified as acute or chronic
0.765 0.235 0.000
M10 Gout
0.765 0.235 0.000
L93 Lupus erythematosus
0.764 0.236 0.000
M31 Other necrotising vasculopathies
0.763 0.237 0.000
I77 Other disorders of arteries and arterioles
0.763 0.237 0.000
D60-D64 Aplastic and other anaemias
0.763 0.237 0.000
M50 Cervical disk disorders
0.762 0.237 0.000
M20.5 Other deformities of toe(s) (acquired)
0.761 0.239 0.000
L05 Pilonidal cyst
0.761 0.239 0.000
S70-S79 Injuries to the hip and thigh
0.760 0.240 0.000
M13.9 Arthritis, unspecified
0.759 0.241 0.000
I45 Other conduction disorders
0.759 0.241 0.000
I70 Atherosclerosis
0.758 0.242 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.756 0.243 0.000
E28 Ovarian dysfunction
0.755 0.244 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.755 0.245 0.000
Z57 Occupational exposure to risk-factors
0.754 0.245 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.754 0.246 0.000
I99 Other and unspecified disorders of circulatory system
0.753 0.247 0.000
I33 Acute and subacute endocarditis
0.753 0.247 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.752 0.248 0.000
G20-G26 Extrapyramidal and movement disorders
0.751 0.249 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.750 0.250 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.750 0.250 0.000
E61 Deficiency of other nutrient elements
0.749 0.251 0.000
J95-J99 Other diseases of the respiratory system
0.749 0.251 0.000
I50.9 Heart failure, unspecified
0.749 0.251 0.000
N18.5 Chronic kidney disease, stage 5
0.749 0.251 0.000
J47 Bronchiectasis
0.748 0.252 0.000
S80-S89 Injuries to the knee and lower leg
0.747 0.253 0.000
E21.3 Hyperparathyroidism, unspecified
0.747 0.253 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.747 0.253 0.000
I44.3 Other and unspecified atrioventricular block
0.747 0.253 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.746 0.254 0.000
N17.9 Acute renal failure, unspecified
0.746 0.254 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.745 0.255 0.000
M80-M85 Disorders of bone density and structure
0.745 0.255 0.000
M25.56 Pain in joint (Lower leg)
0.744 0.256 0.000
G93 Other disorders of brain
0.744 0.256 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.744 0.256 0.000
T40.2 Other opioids
0.744 0.256 0.000
E65 Localised adiposity
0.743 0.257 0.000
B25-B34 Other viral diseases
0.743 0.257 0.000
M05 Seropositive rheumatoid arthritis
0.743 0.257 0.000
J46 Status asthmaticus
0.743 0.257 0.000
M67 Other disorders of synovium and tendon
0.742 0.258 0.000
G56.2 Lesion of ulnar nerve
0.741 0.259 0.000
Chapter XXII Codes for special purposes
0.741 0.259 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.740 0.260 0.000
J18.1 Lobar pneumonia, unspecified
0.740 0.260 0.000
A80-A89 Viral infections of the central nervous system
0.740 0.260 0.000
M79.6 Pain in limb
0.739 0.261 0.000
M86-M90 Other osteopathies
0.739 0.261 0.000
M47 Spondylosis
0.738 0.261 0.000
L90.5 Scar conditions and fibrosis of skin
0.738 0.262 0.000
N10-N16 Renal tubulo-interstitial diseases
0.737 0.263 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.737 0.263 0.000
M54.5 Low back pain
0.737 0.263 0.000
I51.9 Heart disease, unspecified
0.736 0.264 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.735 0.265 0.000
N18.0 End-stage renal disease
0.734 0.266 0.000
M65 Synovitis and tenosynovitis
0.733 0.267 0.000
A41 Other septicaemia
0.733 0.267 0.000
I05-I09 Chronic rheumatic heart diseases
0.732 0.268 0.000
L20-L30 Dermatitis and eczema
0.731 0.268 0.000
M23 Internal derangement of knee
0.731 0.269 0.000
M24 Other specific joint derangements
0.730 0.270 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.730 0.270 0.000
N18.9 Chronic renal failure, unspecified
0.729 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.728 0.272 0.000
Z46 Fitting and adjustment of other devices
0.728 0.272 0.000
E10.9 Without complications
0.728 0.272 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.726 0.274 0.000
Z50.1 Other physical therapy
0.725 0.275 0.000
Z49.1 Extracorporeal dialysis
0.724 0.276 0.000
Z63 Other problems related to primary support group, including family circumstances
0.721 0.279 0.000
A04 Other bacterial intestinal infections
0.721 0.279 0.000
N19 Unspecified renal failure
0.720 0.280 0.000
L81 Other disorders of pigmentation
0.720 0.280 0.000
L90.0 Lichen sclerosus et atrophicus
0.720 0.280 0.000
M07 Psoriatic and enteropathic arthropathies
0.719 0.281 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.718 0.282 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.718 0.282 0.000
E55 Vitamin D deficiency
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E14.9 Without complications
0.717 0.283 0.000
I30.9 Acute pericarditis, unspecified
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
Z90.7 Acquired absence of genital organ(s)
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
M79.8 Other specified soft tissue disorders
0.713 0.287 0.000
I46 Cardiac arrest
0.712 0.288 0.000
Z60.2 Living alone
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.290 0.000
N18.4 Chronic kidney disease, stage 4
0.710 0.290 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.709 0.290 0.000
M79.5 Residual foreign body in soft tissue
0.709 0.291 0.000
S51 Open wound of forearm
0.709 0.291 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.708 0.292 0.000
Z40 Prophylactic surgery
0.707 0.293 0.000
M48.0 Spinal stenosis
0.706 0.294 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.706 0.294 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
Z92 Personal history of medical treatment
0.705 0.295 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.704 0.296 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.704 0.296 0.000
M54.56 Low back pain (Lumbar region)
0.703 0.297 0.000
Z54 Convalescence
0.702 0.297 0.000
Z52 Donors of organs and tissues
0.702 0.297 0.000
Z44 Fitting and adjustment of external prosthetic device
0.702 0.297 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.701 0.299 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.701 0.299 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
M54.2 Cervicalgia
0.699 0.301 0.000
I49.9 Cardiac arrhythmia, unspecified
0.698 0.302 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.697 0.302 0.000
M79.7 Fibromyalgia
0.697 0.303 0.000
I49.3 Ventricular premature depolarisation
0.696 0.304 0.000
E27 Other disorders of adrenal gland
0.696 0.304 0.000
J10 Influenza due to identified influenza virus
0.696 0.304 0.000
I51.6 Cardiovascular disease, unspecified
0.696 0.304 0.000
I51.5 Myocardial degeneration
0.696 0.304 0.000
I51.4 Myocarditis, unspecified
0.696 0.304 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.696 0.304 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.696 0.304 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.696 0.304 0.000
I51.0 Cardiac septal defect, acquired
0.696 0.304 0.000
M11 Other crystal arthropathies
0.696 0.304 0.000
I44.6 Other and unspecified fascicular block
0.695 0.305 0.000
I44.5 Left posterior fascicular block
0.695 0.305 0.000
I44.4 Left anterior fascicular block
0.695 0.305 0.000
Z50.8 Care involving use of rehabilitation procedures
0.695 0.305 0.000
J45.8 Mixed asthma
0.693 0.306 0.000
J45.1 Nonallergic asthma
0.693 0.306 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.692 0.308 0.000
M45 Ankylosing spondylitis
0.692 0.308 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.691 0.309 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.691 0.309 0.000
I47.2 Ventricular tachycardia
0.690 0.310 0.000
E78.2 Mixed hyperlipidaemia
0.690 0.310 0.000
Z51.9 Medical care, unspecified
0.689 0.311 0.000
Z51.6 Desensitisation to allergens
0.689 0.311 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.688 0.312 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.688 0.312 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.688 0.312 0.000
I42.0 Dilated cardiomyopathy
0.688 0.312 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.688 0.312 0.000
M20.1 Hallux valgus (acquired)
0.687 0.313 0.000
B35-B49 Mycoses
0.686 0.314 0.000
G70-G73 Diseases of myoneural junction and muscle
0.686 0.314 0.000
I50.0 Congestive heart failure
0.685 0.315 0.000
L89.1 Stage II decubitus ulcer
0.684 0.315 0.000
E46 Unspecified protein-energy malnutrition
0.684 0.316 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.683 0.317 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
M25.2 Flail joint
0.683 0.317 0.000
M25.1 Fistula of joint
0.683 0.317 0.000
M25.0 Haemarthrosis
0.683 0.317 0.000
I44.0 Atrioventricular block, first degree
0.682 0.317 0.000
M25.76 Osteophyte (Lower leg)
0.682 0.318 0.000
M50.1 Cervical disk disorder with radiculopathy
0.682 0.318 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
L03 Cellulitis
0.681 0.319 0.000
J11 Influenza, virus not identified
0.681 0.319 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.680 0.320 0.000
E34 Other endocrine disorders
0.680 0.320 0.000
E32 Diseases of thymus
0.680 0.320 0.000
E31 Polyglandular dysfunction
0.680 0.320 0.000
E30 Disorders of puberty, not elsewhere classified
0.680 0.320 0.000
E29 Testicular dysfunction
0.680 0.320 0.000
E26 Hyperaldosteronism
0.680 0.320 0.000
E25 Adrenogenital disorders
0.680 0.320 0.000
E24 Cushing's syndrome
0.680 0.320 0.000
E23 Hypofunction and other disorders of pituitary gland
0.680 0.320 0.000
E20 Hypoparathyroidism
0.680 0.320 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.678 0.321 0.000
I74.8 Embolism and thrombosis of other arteries
0.678 0.322 0.000
Z94 Transplanted organ and tissue status
0.677 0.322 0.000
S52 Fracture of forearm
0.677 0.323 0.000
L40-L45 Papulosquamous disorders
0.677 0.323 0.000
E11 Non-insulin-dependent diabetes mellitus
0.676 0.324 0.000
Z43.3 Attention to colostomy
0.676 0.324 0.000
Z50.6 Orthoptic training
0.676 0.324 0.000
Z50.3 Drug rehabilitation
0.676 0.324 0.000
L53 Other erythematous conditions
0.675 0.325 0.000
L04 Acute lymphadenitis
0.675 0.325 0.000
L01 Impetigo
0.675 0.325 0.000
L00 Staphylococcal scalded skin syndrome
0.675 0.325 0.000
Chapter VII Diseases of the eye and adnexa
0.675 0.325 0.000
I71 Aortic aneurysm and dissection
0.674 0.326 0.000
M79.67 Pain in limb (Ankle and foot)
0.674 0.326 0.000
Chapter VIII Diseases of the ear and mastoid process
0.673 0.326 0.000
E05.9 Thyrotoxicosis, unspecified
0.673 0.327 0.000
E66.8 Other obesity
0.673 0.327 0.000
M77 Other enthesopathies
0.672 0.328 0.000
N75 Diseases of Bartholin's gland
0.672 0.328 0.000
M20.3 Other deformity of hallux (acquired)
0.670 0.329 0.000
M14 Arthropathies in other diseases classified elsewhere
0.670 0.330 0.000
M12 Other specific arthropathies
0.670 0.330 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.670 0.330 0.000
M08 Juvenile arthritis
0.670 0.330 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.330 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.330 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.330 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.670 0.330 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.670 0.330 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.330 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.330 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
T36 Poisoning by systemic antibiotics
0.670 0.330 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.669 0.331 0.000
E13 Other specified diabetes mellitus
0.669 0.331 0.000
E12 Malnutrition-related diabetes mellitus
0.669 0.331 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.669 0.331 0.000
M79.0 Rheumatism, unspecified
0.668 0.332 0.000
I72 Other aneurysm
0.668 0.332 0.000
A08 Viral and other specified intestinal infections
0.668 0.332 0.000
E07 Other disorders of thyroid
0.665 0.334 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.665 0.335 0.000
L93.0 Discoid lupus erythematosus
0.664 0.335 0.000
I73 Other peripheral vascular diseases
0.664 0.336 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.664 0.336 0.000
M40-M43 Deforming dorsopathies
0.662 0.338 0.000
I35.9 Aortic valve disorder, unspecified
0.662 0.338 0.000
I78 Diseases of capillaries
0.661 0.339 0.000
E61.1 Iron deficiency
0.661 0.339 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.660 0.340 0.000
M20.4 Other hammer toe(s) (acquired)
0.660 0.340 0.000
E88 Other metabolic disorders
0.660 0.340 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.658 0.342 0.000
I77.6 Arteritis, unspecified
0.658 0.342 0.000
M22.4 Chondromalacia patellae
0.658 0.342 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.657 0.343 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.656 0.343 0.000
M53 Other dorsopathies, not elsewhere classified
0.656 0.344 0.000
D50 Iron deficiency anaemia
0.656 0.344 0.000
M25.74 Osteophyte (Hand)
0.655 0.345 0.000
A46 Erysipelas
0.654 0.346 0.000
Z65 Problems related to other psychosocial circumstances
0.653 0.346 0.000
Z64 Problems related to certain psychosocial circumstances
0.653 0.346 0.000
Z62 Other problems related to upbringing
0.653 0.346 0.000
Z61 Problems related to negative life events in childhood
0.653 0.346 0.000
Z59 Problems related to housing and economic circumstances
0.653 0.346 0.000
Z58 Problems related to physical environment
0.653 0.346 0.000
Z56 Problems related to employment and unemployment
0.653 0.346 0.000
Z55 Problems related to education and literacy
0.653 0.346 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.653 0.347 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.653 0.347 0.000
T78 Adverse effects, not elsewhere classified
0.652 0.348 0.000
T93.2 Sequelae of other fractures of lower limb
0.652 0.348 0.000
M25.77 Osteophyte (Ankle and foot)
0.652 0.348 0.000
E78.8 Other disorders of lipoprotein metabolism
0.650 0.350 0.000
M49 Spondylopathies in diseases classified elsewhere
0.650 0.350 0.000
M76 Enthesopathies of lower limb, excluding foot
0.650 0.350 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.650 0.350 0.000
M71 Other bursopathies
0.650 0.350 0.000
J17 Pneumonia in diseases classified elsewhere
0.649 0.351 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.649 0.351 0.000
J12 Viral pneumonia, not elsewhere classified
0.649 0.351 0.000
J14 Pneumonia due to Haemophilus influenzae
0.649 0.351 0.000
J09 Influenza due to certain identified influenza virus
0.649 0.351 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.648 0.352 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.648 0.352 0.000
L94 Other localised connective tissue disorders
0.648 0.352 0.000
L87 Transepidermal elimination disorders
0.648 0.352 0.000
L88 Pyoderma gangrenosum
0.648 0.352 0.000
L86 Keratoderma in diseases classified elsewhere
0.648 0.352 0.000
L83 Acanthosis nigricans
0.648 0.352 0.000
L80 Vitiligo
0.648 0.352 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.647 0.352 0.000
Z50.2 Alcohol rehabilitation
0.647 0.353 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.646 0.354 0.000
E85 Amyloidosis
0.646 0.354 0.000
E84 Cystic fibrosis
0.646 0.354 0.000
E79 Disorders of purine and pyrimidine metabolism
0.646 0.354 0.000
E77 Disorders of glycoprotein metabolism
0.646 0.354 0.000
E76 Disorders of glycosaminoglycan metabolism
0.646 0.354 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.646 0.354 0.000
E74 Other disorders of carbohydrate metabolism
0.646 0.354 0.000
E73 Lactose intolerance
0.646 0.354 0.000
E72 Other disorders of amino-acid metabolism
0.646 0.354 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.646 0.354 0.000
E70 Disorders of aromatic amino-acid metabolism
0.646 0.354 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.646 0.354 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.645 0.354 0.000
S91 Open wound of ankle and foot
0.645 0.354 0.000
E67 Other hyperalimentation
0.645 0.355 0.000
E68 Sequelae of hyperalimentation
0.645 0.355 0.000
M10.9 Gout, unspecified
0.644 0.356 0.000
D61 Other aplastic anaemias
0.644 0.356 0.000
J18.0 Bronchopneumonia, unspecified
0.643 0.357 0.000
I15 Secondary hypertension
0.643 0.357 0.000
I13 Hypertensive heart and renal disease
0.643 0.357 0.000
I11 Hypertensive heart disease
0.643 0.357 0.000
G91 Hydrocephalus
0.642 0.358 0.000
M25.4 Effusion of joint
0.642 0.358 0.000
Z57.2 Occupational exposure to dust
0.642 0.358 0.000
M21.1 Varus deformity, not elsewhere classified
0.642 0.358 0.000
Z48 Other surgical follow-up care
0.641 0.359 0.000
M46 Other inflammatory spondylopathies
0.641 0.359 0.000
M67.8 Other specified disorders of synovium and tendon
0.641 0.359 0.000
S92.3 Fracture of metatarsal bone
0.641 0.359 0.000
S50 Superficial injury of forearm
0.641 0.359 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.640 0.360 0.000
L08.1 Erythrasma
0.639 0.360 0.000
L08.0 Pyoderma
0.639 0.360 0.000
D51 Vitamin B12 deficiency anaemia
0.639 0.361 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.639 0.361 0.000
T39.1 4-Aminophenol derivatives
0.639 0.361 0.000
M21.6 Other acquired deformities of ankle and foot
0.639 0.361 0.000
I42.9 Cardiomyopathy, unspecified
0.639 0.361 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.638 0.362 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.638 0.362 0.000
M25.78 Osteophyte (Other)
0.638 0.362 0.000
I12.9 Hypertensive renal disease without renal failure
0.637 0.362 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.637 0.363 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.637 0.363 0.000
J43.9 Emphysema, unspecified
0.637 0.363 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.637 0.363 0.000
M48.02 Spinal stenosis (Cervical region)
0.636 0.364 0.000
D80-D89 Certain disorders involving the immune mechanism
0.634 0.366 0.000
D55-D59 Haemolytic anaemias
0.634 0.366 0.000
E10.1 With ketoacidosis
0.633 0.367 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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