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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114590113
log Bayes Factor = 18.6052
Chromosome 4   position 46,984,608  (GRCh37) Explore rs114590113 on Ensembl!
Variant rs114590113 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
Z80 Family history of malignant neoplasm
0.991 0.009 0.000
E70-E90 Metabolic disorders
0.989 0.011 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
H25-H28 Disorders of lens
0.987 0.013 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.979 0.021 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.970 0.030 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.960 0.040 0.000
N60-N64 Disorders of breast
0.957 0.043 0.000
E78.5 Hyperlipidaemia, unspecified
0.955 0.045 0.000
G90-G99 Other disorders of the nervous system
0.955 0.045 0.000
Z90.7 Acquired absence of genital organ(s)
0.954 0.046 0.000
H25 Senile cataract
0.951 0.049 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.950 0.050 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.949 0.051 0.000
F30-F39 Mood [affective] disorders
0.946 0.054 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.944 0.056 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.939 0.061 0.000
Chapter I Certain infectious and parasitic diseases
0.939 0.061 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.937 0.063 0.000
Chapter XXII Codes for special purposes
0.933 0.067 0.000
Chapter VIII Diseases of the ear and mastoid process
0.930 0.070 0.000
N99-N99 Other disorders of the genitourinary system
0.923 0.077 0.000
H26 Other cataract
0.922 0.078 0.000
Z87 Personal history of other diseases and conditions
0.922 0.078 0.000
Z12 Special screening examination for neoplasms
0.921 0.079 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.915 0.085 0.000
Z83 Family history of other specific disorders
0.914 0.086 0.000
G93 Other disorders of brain
0.912 0.088 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.910 0.090 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.909 0.091 0.000
I30-I52 Other forms of heart disease
0.905 0.095 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.893 0.107 0.000
I20-I25 Ischaemic heart diseases
0.893 0.107 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.890 0.110 0.000
I60-I69 Cerebrovascular diseases
0.887 0.113 0.000
Z90.3 Acquired absence of part of stomach
0.886 0.114 0.000
H25.1 Senile nuclear cataract
0.885 0.115 0.000
N80 Endometriosis
0.884 0.116 0.000
Chapter XX External causes of morbidity and mortality
0.877 0.123 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.876 0.124 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.875 0.125 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.875 0.125 0.000
H25.9 Senile cataract, unspecified
0.873 0.127 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.869 0.131 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.865 0.135 0.000
S20-S29 Injuries to the thorax
0.865 0.135 0.000
E78.0 Pure hypercholesterolaemia
0.863 0.137 0.000
N25-N29 Other disorders of kidney and ureter
0.862 0.138 0.000
F32 Depressive episode
0.861 0.139 0.000
I20 Angina pectoris
0.860 0.140 0.000
Chapter X Diseases of the respiratory system
0.860 0.140 0.000
N63 Unspecified lump in breast
0.860 0.140 0.000
Z98 Other postsurgical states
0.859 0.141 0.000
E40-E46 Malnutrition
0.858 0.142 0.000
E20-E35 Disorders of other endocrine glands
0.858 0.142 0.000
N17-N19 Renal failure
0.857 0.143 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.853 0.147 0.000
N80.3 Endometriosis of pelvic peritoneum
0.852 0.148 0.000
Z90.1 Acquired absence of breast(s)
0.851 0.149 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.848 0.152 0.000
I10-I15 Hypertensive diseases
0.847 0.153 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.846 0.154 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
I20.9 Angina pectoris, unspecified
0.843 0.157 0.000
Z89 Acquired absence of limb
0.843 0.157 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.843 0.157 0.000
B95-B98 Bacterial, viral and other infectious agents
0.841 0.159 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.840 0.160 0.000
Z86 Personal history of certain other diseases
0.839 0.161 0.000
Z04 Examination and observation for other reasons
0.836 0.164 0.000
E10-E14 Diabetes mellitus
0.835 0.165 0.000
N40-N51 Diseases of male genital organs
0.831 0.169 0.000
Z96 Presence of other functional implants
0.830 0.170 0.000
I50 Heart failure
0.828 0.172 0.000
H55-H59 Other disorders of eye and adnexa
0.825 0.175 0.000
Z83.7 Family history of diseases of the digestive system
0.825 0.175 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.820 0.180 0.000
N60 Benign mammary dysplasia
0.818 0.182 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.817 0.183 0.000
H90-H95 Other disorders of ear
0.814 0.186 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.813 0.187 0.000
N00-N08 Glomerular diseases
0.812 0.187 0.000
F31 Bipolar affective disorder
0.812 0.188 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
Z90.2 Acquired absence of lung [part of]
0.810 0.190 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.807 0.193 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.807 0.193 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.805 0.195 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.804 0.196 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.804 0.196 0.000
I61 Intracerebral haemorrhage
0.804 0.196 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.803 0.197 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.803 0.197 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.802 0.198 0.000
Z03.3 Observation for suspected nervous system disorder
0.801 0.199 0.000
S00-S09 Injuries to the head
0.800 0.200 0.000
Z86.0 Personal history of other neoplasms
0.798 0.202 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.798 0.202 0.000
H43-H45 Disorders of vitreous body and globe
0.798 0.202 0.000
A30-A49 Other bacterial diseases
0.798 0.202 0.000
S60-S69 Injuries to the wrist and hand
0.797 0.203 0.000
F33 Recurrent depressive disorder
0.797 0.203 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.796 0.204 0.000
E50-E64 Other nutritional deficiencies
0.794 0.205 0.000
E83 Disorders of mineral metabolism
0.794 0.206 0.000
H26.9 Cataract, unspecified
0.794 0.206 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.793 0.207 0.000
H26.8 Other specified cataract
0.791 0.209 0.000
N62 Hypertrophy of breast
0.790 0.210 0.000
G20-G26 Extrapyramidal and movement disorders
0.788 0.212 0.000
O42 Premature rupture of membranes
0.787 0.213 0.000
Z97 Presence of other devices
0.787 0.213 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.784 0.216 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.783 0.217 0.000
G30-G32 Other degenerative diseases of the nervous system
0.782 0.218 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.780 0.220 0.000
H53-H54 Visual disturbances and blindness
0.779 0.221 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.779 0.221 0.000
G93.0 Cerebral cysts
0.779 0.221 0.000
E87.2 Acidosis
0.779 0.221 0.000
I49 Other cardiac arrhythmias
0.778 0.222 0.000
G93.8 Other specified disorders of brain
0.777 0.223 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.776 0.224 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.776 0.224 0.000
Z90.5 Acquired absence of kidney
0.775 0.225 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.775 0.225 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.774 0.226 0.000
N18 Chronic renal failure
0.774 0.226 0.000
H65-H75 Diseases of middle ear and mastoid
0.774 0.226 0.000
N90.5 Atrophy of vulva
0.771 0.229 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.771 0.229 0.000
S40-S49 Injuries to the shoulder and upper arm
0.770 0.229 0.000
S90-S99 Injuries to the ankle and foot
0.767 0.233 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.765 0.235 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.764 0.236 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.764 0.236 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.764 0.236 0.000
S80-S89 Injuries to the knee and lower leg
0.761 0.239 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.760 0.240 0.000
E46 Unspecified protein-energy malnutrition
0.759 0.241 0.000
J90-J94 Other diseases of pleura
0.757 0.243 0.000
S32 Fracture of lumbar spine and pelvis
0.756 0.244 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.755 0.245 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.755 0.245 0.000
N86 Erosion and ectropion of cervix uteri
0.753 0.247 0.000
J40-J47 Chronic lower respiratory diseases
0.752 0.248 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.750 0.250 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.749 0.251 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.748 0.252 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.747 0.253 0.000
Z98.8 Other specified postsurgical states
0.745 0.255 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.745 0.255 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.744 0.255 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.744 0.256 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.744 0.256 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.743 0.257 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.743 0.257 0.000
S50-S59 Injuries to the elbow and forearm
0.743 0.257 0.000
O85-O92 Complications predominantly related to the puerperium
0.742 0.257 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.742 0.258 0.000
B35-B49 Mycoses
0.741 0.259 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.741 0.259 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.741 0.259 0.000
H10-H13 Disorders of conjunctiva
0.740 0.260 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.739 0.261 0.000
E87.0 Hyperosmolality and hypernatraemia
0.738 0.262 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.737 0.263 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.736 0.264 0.000
O42.9 Premature rupture of membranes, unspecified
0.735 0.265 0.000
I63 Cerebral infarction
0.735 0.265 0.000
H26.4 After-cataract
0.735 0.265 0.000
I34 Nonrheumatic mitral valve disorders
0.735 0.265 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.735 0.265 0.000
G93.9 Disorder of brain, unspecified
0.734 0.266 0.000
I47 Paroxysmal tachycardia
0.733 0.267 0.000
G95 Other diseases of spinal cord
0.733 0.267 0.000
F60-F69 Disorders of adult personality and behaviour
0.732 0.268 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.731 0.269 0.000
H80-H83 Diseases of inner ear
0.730 0.269 0.000
O80-O84 Delivery
0.730 0.269 0.000
E65-E68 Obesity and other hyperalimentation
0.730 0.270 0.000
Z03.8 Observation for other suspected diseases and conditions
0.730 0.270 0.000
E27 Other disorders of adrenal gland
0.728 0.272 0.000
G81 Hemiplegia
0.726 0.274 0.000
N50 Other disorders of male genital organs
0.725 0.275 0.000
I50.0 Congestive heart failure
0.724 0.276 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.724 0.276 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.724 0.276 0.000
E87.3 Alkalosis
0.724 0.276 0.000
I12 Hypertensive renal disease
0.723 0.276 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.723 0.277 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.723 0.277 0.000
U88 Agent resistant to multiple antibiotics
0.723 0.277 0.000
E10 Insulin-dependent diabetes mellitus
0.722 0.278 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.722 0.278 0.000
F32.9 Depressive episode, unspecified
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.720 0.279 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.718 0.282 0.000
Z96.8 Presence of other specified functional implants
0.718 0.282 0.000
H92 Otalgia and effusion of ear
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F05.9 Delirium, unspecified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I50.9 Heart failure, unspecified
0.716 0.284 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.716 0.284 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.715 0.284 0.000
F31.9 Bipolar affective disorder, unspecified
0.716 0.284 0.000
N18.9 Chronic renal failure, unspecified
0.715 0.285 0.000
Z83.5 Family history of eye and ear disorders
0.715 0.285 0.000
T66-T78 Other and unspecified effects of external causes
0.714 0.286 0.000
Z90.8 Acquired absence of other organs
0.713 0.286 0.000
Z90.0 Acquired absence of part of head and neck
0.713 0.286 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.713 0.287 0.000
G70-G73 Diseases of myoneural junction and muscle
0.711 0.289 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
G93.6 Cerebral oedema
0.711 0.289 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.710 0.289 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.710 0.289 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.710 0.289 0.000
Z80.6 Family history of leukaemia
0.710 0.289 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.710 0.289 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.710 0.289 0.000
Z71.8 Other specified counselling
0.710 0.290 0.000
E88 Other metabolic disorders
0.709 0.291 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.709 0.291 0.000
N60.1 Diffuse cystic mastopathy
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.707 0.293 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.707 0.293 0.000
H27 Other disorders of lens
0.707 0.293 0.000
N81 Female genital prolapse
0.707 0.293 0.000
I38 Endocarditis, valve unspecified
0.707 0.293 0.000
Z10 Routine general health check-up of defined subpopulation
0.707 0.293 0.000
N80.8 Other endometriosis
0.706 0.294 0.000
U89 Agent resistant to other and unspecified antibiotics
0.705 0.295 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.704 0.296 0.000
E87.5 Hyperkalaemia
0.704 0.296 0.000
F32.0 Mild depressive episode
0.704 0.296 0.000
G93.3 Postviral fatigue syndrome
0.704 0.296 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.702 0.298 0.000
N90.4 Leukoplakia of vulva
0.702 0.298 0.000
H30-H36 Disorders of choroid and retina
0.702 0.298 0.000
F99-F99 Unspecified mental disorder
0.702 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F80-F89 Disorders of psychological development
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
J90 Pleural effusion, not elsewhere classified
0.702 0.298 0.000
E78.8 Other disorders of lipoprotein metabolism
0.702 0.298 0.000
E78.6 Lipoprotein deficiency
0.702 0.298 0.000
E78.4 Other hyperlipidaemia
0.702 0.298 0.000
E78.3 Hyperchylomicronaemia
0.702 0.298 0.000
E78.2 Mixed hyperlipidaemia
0.702 0.298 0.000
E78.1 Pure hyperglyceridaemia
0.702 0.298 0.000
U80 Agent resistant to penicillin and related antibiotics
0.702 0.298 0.000
S20 Superficial injury of thorax
0.702 0.298 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.701 0.299 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.701 0.299 0.000
Z04.8 Examination and observation for other specified reasons
0.699 0.301 0.000
Z02 Examination and encounter for administrative purposes
0.699 0.301 0.000
E28 Ovarian dysfunction
0.698 0.302 0.000
H25.0 Senile incipient cataract
0.698 0.302 0.000
I46 Cardiac arrest
0.698 0.302 0.000
N43 Hydrocele and spermatocele
0.698 0.302 0.000
E87.6 Hypokalaemia
0.697 0.303 0.000
F32.1 Moderate depressive episode
0.697 0.303 0.000
Z82.3 Family history of stroke
0.697 0.303 0.000
I65.2 Occlusion and stenosis of carotid artery
0.696 0.304 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.696 0.304 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.696 0.304 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.696 0.304 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.696 0.304 0.000
Z82.2 Family history of deafness and hearing loss
0.696 0.304 0.000
Z82.1 Family history of blindness and visual loss
0.696 0.304 0.000
N88 Other noninflammatory disorders of cervix uteri
0.695 0.305 0.000
N64 Other disorders of breast
0.693 0.307 0.000
G82 Paraplegia and tetraplegia
0.692 0.308 0.000
G91 Hydrocephalus
0.690 0.310 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.690 0.310 0.000
Z89.5 Acquired absence of leg at or below knee
0.690 0.310 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.689 0.311 0.000
B15-B19 Viral hepatitis
0.688 0.312 0.000
H90 Conductive and sensorineural hearing loss
0.688 0.312 0.000
N10-N16 Renal tubulo-interstitial diseases
0.688 0.312 0.000
H72 Perforation of tympanic membrane
0.688 0.312 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.687 0.313 0.000
A41 Other septicaemia
0.687 0.313 0.000
E14 Unspecified diabetes mellitus
0.687 0.313 0.000
G83 Other paralytic syndromes
0.687 0.313 0.000
N61 Inflammatory disorders of breast
0.686 0.314 0.000
G56 Mononeuropathies of upper limb
0.685 0.315 0.000
N04 Nephrotic syndrome
0.684 0.315 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G96 Other disorders of central nervous system
0.684 0.316 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G90 Disorders of autonomic nervous system
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.684 0.316 0.000
H02 Other disorders of eyelid
0.684 0.316 0.000
I35 Nonrheumatic aortic valve disorders
0.684 0.316 0.000
Z83.3 Family history of diabetes mellitus
0.683 0.317 0.000
H25.2 Senile cataract, morgagnian type
0.682 0.318 0.000
N90.7 Vulvar cyst
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.682 0.318 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.681 0.319 0.000
S61 Open wound of wrist and hand
0.681 0.319 0.000
E83.5 Disorders of calcium metabolism
0.681 0.319 0.000
T87 Complications peculiar to reattachment and amputation
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.320 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.680 0.320 0.000
E87.7 Fluid overload
0.680 0.320 0.000
I20.8 Other forms of angina pectoris
0.680 0.320 0.000
J44 Other chronic obstructive pulmonary disease
0.679 0.321 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.678 0.322 0.000
F38 Other mood [affective] disorders
0.678 0.322 0.000
F34 Persistent mood [affective] disorders
0.678 0.322 0.000
F30 Manic episode
0.678 0.322 0.000
F39 Unspecified mood [affective] disorder
0.678 0.322 0.000
F00 Dementia in Alzheimer's disease
0.678 0.322 0.000
Z93 Artificial opening status
0.677 0.323 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.676 0.324 0.000
Y85 Sequelae of transport accidents
0.675 0.325 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.675 0.325 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.674 0.326 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.674 0.326 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.674 0.326 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.673 0.326 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.326 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.673 0.326 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.673 0.326 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.673 0.326 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.673 0.326 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.673 0.326 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.673 0.326 0.000
T36 Poisoning by systemic antibiotics
0.673 0.326 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.673 0.327 0.000
B99-B99 Other infectious diseases
0.673 0.327 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.673 0.327 0.000
B65-B83 Helminthiases
0.673 0.327 0.000
B50-B64 Protozoal diseases
0.673 0.327 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.673 0.327 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.673 0.327 0.000
A80-A89 Viral infections of the central nervous system
0.673 0.327 0.000
A75-A79 Rickettsioses
0.673 0.327 0.000
A70-A74 Other diseases caused by chlamydiae
0.673 0.327 0.000
A65-A69 Other spirochaetal diseases
0.673 0.327 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.673 0.327 0.000
A20-A28 Certain zoonotic bacterial diseases
0.673 0.327 0.000
A15-A19 Tuberculosis
0.673 0.327 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
Z22 Carrier of infectious disease
0.670 0.330 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.669 0.331 0.000
G25 Other extrapyramidal and movement disorders
0.668 0.332 0.000
I22 Subsequent myocardial infarction
0.667 0.333 0.000
O00-O08 Pregnancy with abortive outcome
0.667 0.333 0.000
Z89.4 Acquired absence of foot and ankle
0.667 0.333 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.666 0.334 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.666 0.334 0.000
Z87.8 Personal history of other specified conditions
0.664 0.336 0.000
T51 Toxic effect of alcohol
0.664 0.336 0.000
I25 Chronic ischaemic heart disease
0.664 0.336 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.664 0.336 0.000
Z96.1 Presence of intraocular lens
0.663 0.337 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.662 0.338 0.000
H26.3 Drug-induced cataract
0.661 0.339 0.000
H26.2 Complicated cataract
0.661 0.339 0.000
H26.1 Traumatic cataract
0.661 0.339 0.000
H26.0 Infantile, juvenile and presenile cataract
0.661 0.339 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.661 0.339 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.661 0.339 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.661 0.339 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.661 0.339 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.661 0.339 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.661 0.339 0.000
Z12.3 Special screening examination for neoplasm of breast
0.661 0.339 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.661 0.339 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.661 0.339 0.000
Z03.1 Observation for suspected malignant neoplasm
0.661 0.339 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.339 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.660 0.340 0.000
N50.1 Vascular disorders of male genital organs
0.660 0.340 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.660 0.340 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.660 0.340 0.000
N80.0 Endometriosis of uterus
0.659 0.341 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.659 0.341 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.659 0.341 0.000
Z80.3 Family history of malignant neoplasm of breast
0.658 0.342 0.000
J95-J99 Other diseases of the respiratory system
0.658 0.342 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
I62 Other nontraumatic intracranial haemorrhage
0.656 0.344 0.000
N98 Complications associated with artificial fertilisation
0.656 0.344 0.000
N91 Absent, scanty and rare menstruation
0.656 0.344 0.000
N82 Fistulae involving female genital tract
0.656 0.344 0.000
N96 Habitual aborter
0.656 0.344 0.000
Z83.6 Family history of diseases of the respiratory system
0.655 0.345 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.655 0.345 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.655 0.345 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.655 0.345 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.655 0.345 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.655 0.345 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.655 0.345 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.655 0.345 0.000
X60-X84 Intentional self-harm
0.654 0.346 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.654 0.346 0.000
G93.7 Reye's syndrome
0.654 0.346 0.000
G93.5 Compression of brain
0.654 0.346 0.000
G93.4 Encephalopathy, unspecified
0.654 0.346 0.000
G93.2 Benign intracranial hypertension
0.654 0.346 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.654 0.346 0.000
I49.1 Atrial premature depolarisation
0.654 0.346 0.000
I10 Essential (primary) hypertension
0.654 0.346 0.000
N17 Acute renal failure
0.653 0.347 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.652 0.347 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.652 0.347 0.000
Z03.0 Observation for suspected tuberculosis
0.652 0.347 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.652 0.348 0.000
E87.4 Mixed disorder of acid-base balance
0.652 0.348 0.000
O47 False labour
0.652 0.348 0.000
S70-S79 Injuries to the hip and thigh
0.651 0.348 0.000
Z04.9 Examination and observation for unspecified reason
0.651 0.348 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.651 0.349 0.000
H57 Other disorders of eye and adnexa
0.651 0.349 0.000
Z94 Transplanted organ and tissue status
0.651 0.349 0.000
I20.1 Angina pectoris with documented spasm
0.651 0.349 0.000
Q00-Q07 Congenital malformations of the nervous system
0.650 0.350 0.000
Z01.4 Gynaecological examination (general)(routine)
0.650 0.350 0.000
F20 Schizophrenia
0.650 0.350 0.000
S02 Fracture of skull and facial bones
0.649 0.351 0.000
I52 Other heart disorders in diseases classified elsewhere
0.649 0.351 0.000
I48 Atrial fibrillation and flutter
0.649 0.351 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.649 0.351 0.000
I41 Myocarditis in diseases classified elsewhere
0.649 0.351 0.000
I40 Acute myocarditis
0.649 0.351 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.649 0.351 0.000
I37 Pulmonary valve disorders
0.649 0.351 0.000
I36 Nonrheumatic tricuspid valve disorders
0.649 0.351 0.000
I33 Acute and subacute endocarditis
0.649 0.351 0.000
I32 Pericarditis in diseases classified elsewhere
0.649 0.351 0.000
I30 Acute pericarditis
0.649 0.351 0.000
I05-I09 Chronic rheumatic heart diseases
0.649 0.351 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.648 0.351 0.000
I74 Arterial embolism and thrombosis
0.648 0.352 0.000
S00 Superficial injury of head
0.648 0.352 0.000
N40 Hyperplasia of prostate
0.647 0.353 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.646 0.354 0.000
I70 Atherosclerosis
0.646 0.354 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.646 0.354 0.000
H46 Optic neuritis
0.645 0.355 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.644 0.356 0.000
I69 Sequelae of cerebrovascular disease
0.643 0.357 0.000
G58 Other mononeuropathies
0.643 0.357 0.000
T92 Sequelae of injuries of upper limb
0.642 0.358 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.642 0.358 0.000
H04 Disorders of lachrymal system
0.642 0.358 0.000
N80.1 Endometriosis of ovary
0.642 0.358 0.000
J20-J22 Other acute lower respiratory infections
0.641 0.359 0.000
Q50-Q56 Congenital malformations of genital organs
0.641 0.359 0.000
I49.0 Ventricular fibrillation and flutter
0.641 0.359 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.640 0.360 0.000
S37 Injury of urinary and pelvic organs
0.640 0.360 0.000
S36 Injury of intra-abdominal organs
0.640 0.360 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.640 0.360 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.640 0.360 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.640 0.360 0.000
S31 Open wound of abdomen, lower back and pelvis
0.640 0.360 0.000
I23 Certain current complications following acute myocardial infarction
0.640 0.360 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.640 0.360 0.000
S06 Intracranial injury
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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