TreeWAS – Variant ID: rs114796104

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
E83 Disorders of mineral metabolism	0.486	0.508	0.006
E83.3 Disorders of phosphorus metabolism	0.374	0.623	0.004
E83.9 Disorder of mineral metabolism, unspecified	0.348	0.647	0.005
E83.8 Other disorders of mineral metabolism	0.348	0.647	0.005
E83.2 Disorders of zinc metabolism	0.348	0.647	0.005
E83.0 Disorders of copper metabolism	0.348	0.647	0.005
E83.5 Disorders of calcium metabolism	0.347	0.651	0.002
E83.4 Disorders of magnesium metabolism	0.336	0.660	0.004
E78.0 Pure hypercholesterolaemia	0.000	0.791	0.209
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.005	0.846	0.149
E78.2 Mixed hyperlipidaemia	0.002	0.871	0.127
E78.5 Hyperlipidaemia, unspecified	0.000	0.875	0.124
E78.8 Other disorders of lipoprotein metabolism	0.003	0.889	0.108
E78.6 Lipoprotein deficiency	0.003	0.889	0.107
E78.3 Hyperchylomicronaemia	0.003	0.889	0.107
E78.1 Pure hyperglyceridaemia	0.003	0.889	0.107
E78.4 Other hyperlipidaemia	0.003	0.891	0.105
E70-E90 Metabolic disorders	0.055	0.897	0.047
E78.9 Disorder of lipoprotein metabolism, unspecified	0.004	0.904	0.092
E85 Amyloidosis	0.040	0.926	0.034
E84 Cystic fibrosis	0.040	0.926	0.034
E79 Disorders of purine and pyrimidine metabolism	0.040	0.926	0.034
E77 Disorders of glycoprotein metabolism	0.040	0.926	0.034
E76 Disorders of glycosaminoglycan metabolism	0.040	0.926	0.034
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.040	0.926	0.034
E74 Other disorders of carbohydrate metabolism	0.040	0.926	0.034
E73 Lactose intolerance	0.040	0.926	0.034
E72 Other disorders of amino-acid metabolism	0.040	0.926	0.034
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.040	0.926	0.034
E70 Disorders of aromatic amino-acid metabolism	0.040	0.926	0.034
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.040	0.926	0.034
E88 Other metabolic disorders	0.039	0.929	0.032
E80 Disorders of porphyrin and bilirubin metabolism	0.042	0.929	0.029
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.043	0.937	0.020
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.029	0.947	0.024
E70.8 Other disorders of aromatic amino-acid metabolism	0.029	0.947	0.024
E70.3 Albinism	0.029	0.947	0.024
E70.2 Disorders of tyrosine metabolism	0.029	0.947	0.024
E70.1 Other hyperphenylalaninaemias	0.029	0.947	0.024
E70.0 Classical phenylketonuria	0.029	0.947	0.024
E71.3 Disorders of fatty-acid metabolism	0.029	0.947	0.024
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.029	0.947	0.024
E71.1 Other disorders of branched-chain amino-acid metabolism	0.029	0.947	0.024
E71.0 Maple-syrup-urine disease	0.029	0.947	0.024
E72.9 Disorder of amino-acid metabolism, unspecified	0.029	0.947	0.024
E72.8 Other specified disorders of amino-acid metabolism	0.029	0.947	0.024
E72.5 Disorders of glycine metabolism	0.029	0.947	0.024
E72.4 Disorders of ornithine metabolism	0.029	0.947	0.024
E72.3 Disorders of lysine and hydroxylysine metabolism	0.029	0.947	0.024
E72.2 Disorders of urea cycle metabolism	0.029	0.947	0.024
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.029	0.947	0.024
E72.0 Disorders of amino-acid transport	0.029	0.947	0.024
E73.9 Lactose intolerance, unspecified	0.029	0.947	0.024
E73.8 Other lactose intolerance	0.029	0.947	0.024
E73.1 Secondary lactase deficiency	0.029	0.947	0.024
E73.0 Congenital lactase deficiency	0.029	0.947	0.024
E74.9 Disorder of carbohydrate metabolism, unspecified	0.029	0.947	0.024
E74.8 Other specified disorders of carbohydrate metabolism	0.029	0.947	0.024
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.029	0.947	0.024
E74.3 Other disorders of intestinal carbohydrate absorption	0.029	0.947	0.024
E74.2 Disorders of galactose metabolism	0.029	0.947	0.024
E74.1 Disorders of fructose metabolism	0.029	0.947	0.024
E74.0 Glycogen storage disease	0.029	0.947	0.024
E75.6 Lipid storage disorder, unspecified	0.029	0.947	0.024
E75.5 Other lipid storage disorders	0.029	0.947	0.024
E75.4 Neuronal ceroid lipofuscinosis	0.029	0.947	0.024
E75.3 Sphingolipidosis, unspecified	0.029	0.947	0.024
E75.2 Other sphingolipidosis	0.029	0.947	0.024
E75.1 Other gangliosidosis	0.029	0.947	0.024
E75.0 GM2 gangliosidosis	0.029	0.947	0.024
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.029	0.947	0.024
E76.8 Other disorders of glucosaminoglycan metabolism	0.029	0.947	0.024
E76.3 Mucopolysaccharidosis, unspecified	0.029	0.947	0.024
E76.2 Other mucopolysaccharidoses	0.029	0.947	0.024
E76.1 Mucopolysaccharidosis, type II	0.029	0.947	0.024
E76.0 Mucopolysaccharidosis, type I	0.029	0.947	0.024
E77.9 Disorder of glycoprotein metabolism, unspecified	0.029	0.947	0.024
E77.8 Other disorders of glycoprotein metabolism	0.029	0.947	0.024
E77.1 Defects in glycoprotein degradation	0.029	0.947	0.024
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.029	0.947	0.024
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.029	0.947	0.024
E79.8 Other disorders of purine and pyrimidine metabolism	0.029	0.947	0.024
E79.1 Lesch-Nyhan syndrome	0.029	0.947	0.024
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.029	0.947	0.024
E84.9 Cystic fibrosis, unspecified	0.029	0.947	0.024
E84.8 Cystic fibrosis with other manifestations	0.029	0.947	0.024
E84.1 Cystic fibrosis with intestinal manifestations	0.029	0.947	0.024
E84.0 Cystic fibrosis with pulmonary manifestations	0.029	0.947	0.024
E85.9 Amyloidosis, unspecified	0.029	0.947	0.024
E85.8 Other amyloidosis	0.029	0.947	0.024
E85.4 Organ-limited amyloidosis	0.029	0.947	0.024
E85.3 Secondary systemic amyloidosis	0.029	0.947	0.024
E85.2 Heredofamilial amyloidosis, unspecified	0.029	0.947	0.024
E85.1 Neuropathic heredofamilial amyloidosis	0.029	0.947	0.024
E85.0 Nonneuropathic heredofamilial amyloidosis	0.029	0.947	0.024
E88.9 Metabolic disorder, unspecified	0.028	0.949	0.023
E88.8 Other specified metabolic disorders	0.028	0.949	0.023
E88.3 Tumour lysis syndrome	0.028	0.949	0.023
E88.2 Lipomatosis, not elsewhere classified	0.028	0.949	0.023
E88.1 Lipodystrophy, not elsewhere classified	0.028	0.949	0.023
E80.7 Disorder of bilirubin metabolism, unspecified	0.030	0.949	0.021
E80.6 Other disorders of bilirubin metabolism	0.030	0.949	0.021
E80.5 Crigler-Najjar syndrome	0.030	0.949	0.021
E80.3 Defects of catalase and peroxydase	0.030	0.949	0.021
E80.2 Other porphyria	0.030	0.949	0.021
E80.1 Porphyria cutanea tarda	0.030	0.949	0.021
E80.0 Hereditary erythropoietic porphyria	0.030	0.949	0.021
E87 Other disorders of fluid, electrolyte and acid-base balance	0.003	0.951	0.047
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.028	0.952	0.021
E80.4 Gilbert's syndrome	0.033	0.952	0.015
E86 Volume depletion	0.042	0.952	0.006
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.954	0.045
E89.3 Postprocedural hypopituitarism	0.033	0.954	0.013
E89.2 Postprocedural hypoparathyroidism	0.032	0.955	0.013
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.031	0.955	0.014
E89.8 Other postprocedural endocrine and metabolic disorders	0.031	0.955	0.014
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.031	0.955	0.014
E89.5 Postprocedural testicular hypofunction	0.031	0.955	0.014
E89.4 Postprocedural ovarian failure	0.031	0.955	0.014
E89.1 Postprocedural hypoinsulinaemia	0.031	0.955	0.014
E87.6 Hypokalaemia	0.000	0.959	0.041
E87.7 Fluid overload	0.001	0.959	0.040
E89.0 Postprocedural hypothyroidism	0.030	0.962	0.008
E87.3 Alkalosis	0.002	0.963	0.035
E87.4 Mixed disorder of acid-base balance	0.002	0.965	0.034
E87.5 Hyperkalaemia	0.001	0.965	0.034
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.002	0.967	0.031
E87.0 Hyperosmolality and hypernatraemia	0.002	0.968	0.031
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.972	0.028
K57 Diverticular disease of intestine	0.000	0.975	0.025
Chapter IV Endocrine, nutritional and metabolic diseases	0.005	0.976	0.019
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.976	0.024
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.977	0.023
E10.9 Without complications	0.000	0.979	0.021
E10-E14 Diabetes mellitus	0.001	0.980	0.019
E10 Insulin-dependent diabetes mellitus	0.000	0.980	0.020
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.981	0.019
E87.2 Acidosis	0.002	0.981	0.017
E14 Unspecified diabetes mellitus	0.000	0.982	0.018
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.982	0.018
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.982	0.018
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.982	0.018
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.983	0.017
E14.9 Without complications	0.000	0.983	0.017
E50-E64 Other nutritional deficiencies	0.003	0.983	0.014
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.983	0.014
E40-E46 Malnutrition	0.004	0.983	0.013
E10.1 With ketoacidosis	0.000	0.984	0.016
E13 Other specified diabetes mellitus	0.000	0.984	0.015
E10.3 With ophthalmic complications	0.000	0.984	0.016
E65-E68 Obesity and other hyperalimentation	0.003	0.985	0.012
G35 Multiple sclerosis	0.015	0.985	0.000
E12 Malnutrition-related diabetes mellitus	0.001	0.985	0.014
E10.8 With unspecified complications	0.000	0.985	0.014
E10.7 With multiple complications	0.000	0.985	0.014
E10.6 With other specified complications	0.000	0.985	0.014
E10.2 With renal complications	0.000	0.985	0.014
E10.0 With coma	0.000	0.985	0.014
E61 Deficiency of other nutrient elements	0.002	0.986	0.012
E14.8 With unspecified complications	0.000	0.987	0.013
E14.7 With multiple complications	0.000	0.987	0.013
E14.6 With other specified complications	0.000	0.987	0.013
E14.5 With peripheral circulatory complications	0.000	0.987	0.013
E14.4 With neurological complications	0.000	0.987	0.013
E14.2 Withrenal complications	0.000	0.987	0.013
E14.1 With ketoacidosis	0.000	0.987	0.013
E14.0 With coma	0.000	0.987	0.013
E14.3 With ophthalmic complications	0.000	0.987	0.013
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.013	0.987	0.000
E13.9 Without complications	0.000	0.987	0.013
E10.4 With neurological complications	0.000	0.987	0.012
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.987	0.010
E63 Other nutritional deficiencies	0.002	0.987	0.010
E56 Other vitamin deficiencies	0.002	0.987	0.010
E51 Thiamine deficiency	0.002	0.987	0.010
E50 Vitamin A deficiency	0.002	0.987	0.010
E60 Dietary zinc deficiency	0.002	0.987	0.010
E59 Dietary selenium deficiency	0.002	0.987	0.010
E58 Dietary calcium deficiency	0.002	0.987	0.010
E54 Ascorbic acid deficiency	0.002	0.987	0.010
E52 Niacin deficiency [pellagra]	0.002	0.987	0.010
E15 Nondiabetic hypoglycaemic coma	0.002	0.988	0.010
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.988	0.009
E45 Retarded development following protein-energy malnutrition	0.003	0.988	0.009
E43 Unspecified severe protein-energy malnutrition	0.003	0.988	0.009
E42 Marasmic kwashiorkor	0.003	0.988	0.009
E41 Nutritional marasmus	0.003	0.988	0.009
E40 Kwashiorkor	0.003	0.988	0.009
E55 Vitamin D deficiency	0.002	0.988	0.010
E16 Other disorders of pancreatic internal secretion	0.002	0.988	0.010
E13.8 With unspecified complications	0.000	0.988	0.011
E13.7 With multiple complications	0.000	0.988	0.011
E13.6 With other specified complications	0.000	0.988	0.011
E13.5 With peripheral circulatory complications	0.000	0.988	0.011
E13.4 With neurological complications	0.000	0.988	0.011
E13.3 With ophthalmic complications	0.000	0.988	0.011
E13.2 With renal complications	0.000	0.988	0.011
E13.1 With ketoacidosis	0.000	0.988	0.011
E13.0 With coma	0.000	0.988	0.011
E46 Unspecified protein-energy malnutrition	0.003	0.988	0.009
E61.1 Iron deficiency	0.001	0.989	0.011
E53 Deficiency of other B group vitamins	0.002	0.989	0.009
E67 Other hyperalimentation	0.002	0.989	0.009
E68 Sequelae of hyperalimentation	0.002	0.989	0.009
E12.9 Without complications	0.001	0.989	0.010
E12.8 With unspecified complications	0.001	0.989	0.010
E12.7 With multiple complications	0.001	0.989	0.010
E12.6 With other specified complications	0.001	0.989	0.010
E12.5 With peripheral circulatory complications	0.001	0.989	0.010
E12.4 With neurological complications	0.001	0.989	0.010
E12.3 With ophthalmic complications	0.001	0.989	0.010
E12.2 With renal complications	0.001	0.989	0.010
E12.1 With ketoacidosis	0.001	0.989	0.010
E12.0 With coma	0.001	0.989	0.010
E10.5 With peripheral circulatory complications	0.001	0.990	0.010
E61.9 Deficiency of nutrient element, unspecified	0.001	0.990	0.009
E61.8 Deficiency of other specified nutrient elements	0.001	0.990	0.009
E61.7 Deficiency of multiple nutrient elements	0.001	0.990	0.009
E61.6 Vanadium deficiency	0.001	0.990	0.009
E61.5 Molybdenum deficiency	0.001	0.990	0.009
E61.4 Chromium deficiency	0.001	0.990	0.009
E61.3 Manganese deficiency	0.001	0.990	0.009
E61.2 Magnesium deficiency	0.001	0.990	0.009
E61.0 Copper deficiency	0.001	0.990	0.009
E65 Localised adiposity	0.002	0.990	0.008
E20-E35 Disorders of other endocrine glands	0.005	0.990	0.005
E50.9 Vitamin A deficiency, unspecified	0.002	0.991	0.008
E50.8 Other manifestations of vitamin A deficiency	0.002	0.991	0.008
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.991	0.008
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.991	0.008
E50.5 Vitamin A deficiency with night blindness	0.002	0.991	0.008
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.991	0.008
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.991	0.008
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.991	0.008
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.991	0.008
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.991	0.008
E51.9 Thiamine deficiency, unspecified	0.002	0.991	0.008
E51.8 Other manifestations of thiamine deficiency	0.002	0.991	0.008
E51.2 Wernicke's encephalopathy	0.002	0.991	0.008
E51.1 Beriberi	0.002	0.991	0.008
E56.9 Vitamin deficiency, unspecified	0.002	0.991	0.008
E56.8 Deficiency of other vitamins	0.002	0.991	0.008
E56.1 Deficiency of vitamin K	0.002	0.991	0.008
E56.0 Deficiency of vitamin E	0.002	0.991	0.008
E63.9 Nutritional deficiency, unspecified	0.002	0.991	0.008
E63.8 Other specified nutritional deficiencies	0.002	0.991	0.008
E63.1 Imbalance of constituents of food intake	0.002	0.991	0.008
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.991	0.008
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.991	0.008
E64.8 Sequelae of other nutritional deficiencies	0.002	0.991	0.008
E64.3 Sequelae of rickets	0.002	0.991	0.008
E64.2 Sequelae of vitamin C deficiency	0.002	0.991	0.008
E64.1 Sequelae of vitamin A deficiency	0.002	0.991	0.008
E64.0 Sequelae of protein-energy malnutrition	0.002	0.991	0.008
E00-E07 Disorders of thyroid gland	0.003	0.991	0.006
E66 Obesity	0.001	0.991	0.009
E44.1 Mild protein-energy malnutrition	0.002	0.991	0.007
E44.0 Moderate protein-energy malnutrition	0.002	0.991	0.007
E55.0 Rickets, active	0.001	0.991	0.008
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.991	0.007
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.991	0.007
E16.4 Abnormal secretion of gastrin	0.001	0.991	0.007
E16.3 Increased secretion of glucagon	0.001	0.991	0.007
E16.1 Other hypoglycaemia	0.001	0.991	0.007
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.991	0.007
L29.0 Pruritus ani	0.009	0.991	0.000
E55.9 Vitamin D deficiency, unspecified	0.001	0.991	0.007
G35-G37 Demyelinating diseases of the central nervous system	0.009	0.991	0.000
E16.2 Hypoglycaemia, unspecified	0.001	0.992	0.008
E53.9 Vitamin B deficiency, unspecified	0.001	0.992	0.007
E53.1 Pyridoxine deficiency	0.001	0.992	0.007
E53.0 Riboflavin deficiency	0.001	0.992	0.007
L29 Pruritus	0.008	0.992	0.000
E67.8 Other specified hyperalimentation	0.002	0.992	0.007
E67.3 Hypervitaminosis D	0.002	0.992	0.007
E67.2 Megavitamin-B6 syndrome	0.002	0.992	0.007
E67.1 Hypercarotenaemia	0.002	0.992	0.007
E67.0 Hypervitaminosis A	0.002	0.992	0.007
L29.2 Pruritus vulvae	0.008	0.992	0.000
L20-L30 Dermatitis and eczema	0.007	0.993	0.000
G37 Other demyelinating diseases of central nervous system	0.007	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.993	0.004
E32 Diseases of thymus	0.004	0.993	0.004
E31 Polyglandular dysfunction	0.004	0.993	0.004
E30 Disorders of puberty, not elsewhere classified	0.004	0.993	0.004
E29 Testicular dysfunction	0.004	0.993	0.003
E26 Hyperaldosteronism	0.004	0.993	0.004
E25 Adrenogenital disorders	0.004	0.993	0.004
E24 Cushing's syndrome	0.004	0.993	0.004
E20 Hypoparathyroidism	0.004	0.993	0.004
K22.8 Other specified diseases of oesophagus	0.000	0.993	0.007
E34 Other endocrine disorders	0.004	0.993	0.003
L30 Other dermatitis	0.007	0.993	0.000
E66.8 Other obesity	0.000	0.993	0.007
E22 Hyperfunction of pituitary gland	0.004	0.993	0.004
E28 Ovarian dysfunction	0.004	0.993	0.003
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.993	0.004
E00 Congenital iodine-deficiency syndrome	0.002	0.993	0.004
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.993	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.993	0.003
E53.8 Deficiency of other specified B group vitamins	0.001	0.993	0.006
E66.2 Extreme obesity with alveolar hypoventilation	0.001	0.993	0.006
E66.1 Drug-induced obesity	0.001	0.993	0.006
E66.0 Obesity due to excess calories	0.001	0.993	0.006
E27 Other disorders of adrenal gland	0.004	0.993	0.003
L30.9 Dermatitis, unspecified	0.007	0.993	0.000
E07 Other disorders of thyroid	0.002	0.993	0.004
E06 Thyroiditis	0.003	0.994	0.004
G36 Other acute disseminated demyelination	0.006	0.994	0.000
L27 Dermatitis due to substances taken internally	0.006	0.994	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.006	0.994	0.000
L29.8 Other pruritus	0.006	0.994	0.000
L29.3 Anogenital pruritus, unspecified	0.006	0.994	0.000
L29.1 Pruritus scroti	0.006	0.994	0.000
E03 Other hypothyroidism	0.001	0.994	0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.994	0.003
L30.8 Other specified dermatitis	0.006	0.994	0.000
L25 Unspecified contact dermatitis	0.006	0.994	0.000
L24 Irritant contact dermatitis	0.006	0.994	0.000
L23 Allergic contact dermatitis	0.006	0.994	0.000
L21 Seborrhoeic dermatitis	0.006	0.994	0.000
L20 Atopic dermatitis	0.006	0.994	0.000
L26 Exfoliative dermatitis	0.006	0.994	0.000
L22 Diaper [napkin] dermatitis	0.006	0.994	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.994	0.005
E29.1 Testicular hypofunction	0.004	0.994	0.001
L27.0 Generalised skin eruption due to drugs and medicaments	0.005	0.994	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.005	0.994	0.000
G37.5 Concentric sclerosis [Balo]	0.005	0.994	0.000
G37.4 Subacute necrotising myelitis	0.005	0.994	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.005	0.994	0.000
G37.2 Central pontine myelinolysis	0.005	0.994	0.000
G37.1 Central demyelination of corpus callosum	0.005	0.994	0.000
G37.0 Diffuse sclerosis	0.005	0.994	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.006	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.995	0.003
E20.8 Other hypoparathyroidism	0.003	0.995	0.003
E20.1 Pseudohypoparathyroidism	0.003	0.995	0.003
E20.0 Idiopathic hypoparathyroidism	0.003	0.995	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.995	0.003
E24.8 Other Cushing's syndrome	0.003	0.995	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.995	0.003
E24.3 Ectopic ACTH syndrome	0.003	0.995	0.003
E24.2 Drug-induced Cushing's syndrome	0.003	0.995	0.003
E24.1 Nelson's syndrome	0.003	0.995	0.003
E24.0 Pituitary-dependent Cushing's disease	0.003	0.995	0.003
E25.9 Adrenogenital disorder, unspecified	0.003	0.995	0.003
E25.8 Other adrenogenital disorders	0.003	0.995	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.995	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.995	0.003
E26.8 Other hyperaldosteronism	0.003	0.995	0.003
E26.1 Secondary hyperaldosteronism	0.003	0.995	0.003
E26.0 Primary hyperaldosteronism	0.003	0.995	0.003
E29.9 Testicular dysfunction, unspecified	0.003	0.995	0.002
E29.8 Other testicular dysfunction	0.003	0.995	0.002
E29.0 Testicular hyperfunction	0.003	0.995	0.002
E30.9 Disorder of puberty, unspecified	0.003	0.995	0.003
E30.8 Other disorders of puberty	0.003	0.995	0.003
E30.1 Precocious puberty	0.003	0.995	0.003
E30.0 Delayed puberty	0.003	0.995	0.003
E31.9 Polyglandular dysfunction, unspecified	0.003	0.995	0.003
E31.8 Other polyglandular dysfunction	0.003	0.995	0.003
E31.1 Polyglandular hyperfunction	0.003	0.995	0.003
E31.0 Autoimmune polyglandular failure	0.003	0.995	0.003
E32.9 Disease of thymus, unspecified	0.003	0.995	0.003
E32.8 Other diseases of thymus	0.003	0.995	0.003
E32.1 Abscess of thymus	0.003	0.995	0.003
E32.0 Persistent hyperplasia of thymus	0.003	0.995	0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.995	0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.995	0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.995	0.003
E34.8 Other specified endocrine disorders	0.003	0.995	0.003
E34.5 Androgen resistance syndrome	0.003	0.995	0.003
E34.4 Constitutional tall stature	0.003	0.995	0.003
E34.3 Short stature, not elsewhere classified	0.003	0.995	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.995	0.003
E34.1 Other hypersecretion of intestinal hormones	0.003	0.995	0.003
E34.0 Carcinoid syndrome	0.003	0.995	0.003
L28 Lichen simplex chronicus and prurigo	0.005	0.995	0.000
E28.3 Primary ovarian failure	0.004	0.995	0.002
L30.5 Pityriasis alba	0.005	0.995	0.000
L30.4 Erythema intertrigo	0.005	0.995	0.000
L30.3 Infective dermatitis	0.005	0.995	0.000
L30.2 Cutaneous autosensitisation	0.005	0.995	0.000
L30.1 Dyshidrosis [pompholyx]	0.005	0.995	0.000
L30.0 Nummular dermatitis	0.005	0.995	0.000
L40.5 Arthropathic psoriasis	0.000	0.995	0.005
L40 Psoriasis	0.001	0.995	0.005
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.995	0.003
E22.8 Other hyperfunction of pituitary gland	0.003	0.995	0.003
E22.1 Hyperprolactinaemia	0.003	0.995	0.003
E22.0 Acromegaly and pituitary gigantism	0.003	0.995	0.003
E28.9 Ovarian dysfunction, unspecified	0.003	0.995	0.002
E28.8 Other ovarian dysfunction	0.003	0.995	0.002
E28.1 Androgen excess	0.003	0.995	0.002
E28.0 Oestrogen excess	0.003	0.995	0.002
E34.9 Endocrine disorder, unspecified	0.003	0.995	0.003
E23.2 Diabetes insipidus	0.004	0.995	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.995	0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.995	0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.995	0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.995	0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.995	0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.995	0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.995	0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.995	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.995	0.002
E23.6 Other disorders of pituitary gland	0.003	0.995	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.995	0.002
E23.1 Drug-induced hypopituitarism	0.003	0.995	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.005	0.995	0.000
L40.9 Psoriasis, unspecified	0.000	0.995	0.005
E27.9 Disorder of adrenal gland, unspecified	0.003	0.995	0.002
E27.8 Other specified disorders of adrenal gland	0.003	0.995	0.002
E27.5 Adrenomedullary hyperfunction	0.003	0.995	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.995	0.002
E27.2 Addisonian crisis	0.003	0.995	0.002
E27.0 Other adrenocortical overactivity	0.003	0.995	0.002
E28.2 Polycystic ovarian syndrome	0.004	0.995	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.995	0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.995	0.003
E23.0 Hypopituitarism	0.004	0.995	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.995	0.002
L40-L45 Papulosquamous disorders	0.004	0.995	0.001
E27.1 Primary adrenocortical insufficiency	0.003	0.995	0.002
E66.9 Obesity, unspecified	0.000	0.995	0.005
E07.8 Other specified disorders of thyroid	0.002	0.995	0.003
E07.1 Dyshormogenetic goitre	0.002	0.995	0.003
E07.0 Hypersecretion of calcitonin	0.002	0.995	0.003
E06.9 Thyroiditis, unspecified	0.002	0.995	0.003
E06.5 Other chronic thyroiditis	0.002	0.995	0.003
E06.4 Drug-induced thyroiditis	0.002	0.995	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.995	0.003
E06.1 Subacute thyroiditis	0.002	0.995	0.003
E06.0 Acute thyroiditis	0.002	0.995	0.003
G36.9 Acute disseminated demyelination, unspecified	0.005	0.995	0.000
G36.8 Other specified acute disseminated demyelination	0.005	0.995	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.005	0.995	0.000
G36.0 Neuromyelitis optica [Devic]	0.005	0.995	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.005	0.995	0.000
L27.8 Dermatitis due to other substances taken internally	0.005	0.995	0.000
L27.2 Dermatitis due to ingested food	0.005	0.995	0.000
L43.9 Lichen planus, unspecified	0.005	0.995	0.000
L03.1 Cellulitis of other parts of limb	0.005	0.995	0.000
E03.8 Other specified hypothyroidism	0.001	0.995	0.004
E03.5 Myxoedema coma	0.001	0.995	0.004
E03.4 Atrophy of thyroid (acquired)	0.001	0.995	0.004
E03.3 Postinfectious hypothyroidism	0.001	0.995	0.004
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.995	0.004
E03.1 Congenital hypothyroidism without goitre	0.001	0.995	0.004
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.995	0.004
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.995	0.003
E21.4 Other specified disorders of parathyroid gland	0.002	0.995	0.003
E21.2 Other hyperparathyroidism	0.002	0.995	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.995	0.003
L43 Lichen planus	0.004	0.995	0.001
E04 Other non-toxic goitre	0.003	0.995	0.002
Chapter XII Diseases of the skin and subcutaneous tissue	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.003	0.995	0.002
E07.9 Disorder of thyroid, unspecified	0.002	0.996	0.003
L40.0 Psoriasis vulgaris	0.000	0.996	0.004
E11.1 With ketoacidosis	0.000	0.996	0.004
L20.9 Atopic dermatitis, unspecified	0.004	0.996	0.000
L20.8 Other atopic dermatitis	0.004	0.996	0.000
L20.0 Besnier's prurigo	0.004	0.996	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.004	0.996	0.000
L21.8 Other seborrhoeic dermatitis	0.004	0.996	0.000
L21.1 Seborrhoeic infantile dermatitis	0.004	0.996	0.000
L21.0 Seborrhoea capitis	0.004	0.996	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.004	0.996	0.000
L23.8 Allergic contact dermatitis due to other agents	0.004	0.996	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.004	0.996	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.004	0.996	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.004	0.996	0.000
L23.4 Allergic contact dermatitis due to dyes	0.004	0.996	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.004	0.996	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.004	0.996	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.004	0.996	0.000
L23.0 Allergic contact dermatitis due to metals	0.004	0.996	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.004	0.996	0.000
L24.8 Irritant contact dermatitis due to other agents	0.004	0.996	0.000
L24.7 Irritant contact dermatitis due to plants, except food	0.004	0.996	0.000
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.004	0.996	0.000
L24.5 Irritant contact dermatitis due to other chemical products	0.004	0.996	0.000
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.004	0.996	0.000
L24.3 Irritant contact dermatitis due to cosmetics	0.004	0.996	0.000
L24.2 Irritant contact dermatitis due to solvents	0.004	0.996	0.000
L24.1 Irritant contact dermatitis due to oils and greases	0.004	0.996	0.000
L24.0 Irritant contact dermatitis due to detergents	0.004	0.996	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.004	0.996	0.000
L25.8 Unspecified contact dermatitis due to other agents	0.004	0.996	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.004	0.996	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.004	0.996	0.000
L25.3 Unspecified contact dermatitis due to other chemical products	0.004	0.996	0.000
L25.2 Unspecified contact dermatitis due to dyes	0.004	0.996	0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.004	0.996	0.000
L25.0 Unspecified contact dermatitis due to cosmetics	0.004	0.996	0.000
L29.9 Pruritus, unspecified	0.004	0.996	0.000
K22.4 Dyskinesia of oesophagus	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations