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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114848727
log Bayes Factor = 32.9543
Chromosome 6   position 58,744,020  (GRCh37) Explore rs114848727 on Ensembl!
Variant rs114848727 is part of Cluster X0271

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.998 0.002 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.998 0.002 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.995 0.005 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.991 0.009 0.000
Chapter II Neoplasms
0.990 0.010 0.000
O60-O75 Complications of labour and delivery
0.988 0.012 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.987 0.013 0.000
Z95.1 Presence of aortocoronary bypass graft
0.985 0.015 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.984 0.016 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.982 0.018 0.000
I71 Aortic aneurysm and dissection
0.980 0.020 0.000
E86 Volume depletion
0.977 0.023 0.000
M05-M14 Inflammatory polyarthropathies
0.975 0.025 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.974 0.026 0.000
I25.1 Atherosclerotic heart disease
0.971 0.029 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.970 0.030 0.000
F10.2 Dependence syndrome
0.970 0.030 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.969 0.031 0.000
F10.1 Harmful use
0.965 0.035 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.965 0.035 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.964 0.036 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.964 0.036 0.000
M10 Gout
0.958 0.042 0.000
Chapter VIII Diseases of the ear and mastoid process
0.957 0.043 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.956 0.044 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.954 0.046 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.951 0.049 0.000
M10.9 Gout, unspecified
0.947 0.053 0.000
C79 Secondary malignant neoplasm of other sites
0.947 0.053 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.946 0.054 0.000
E83 Disorders of mineral metabolism
0.943 0.057 0.000
O36 Maternal care for other known or suspected foetal problems
0.943 0.057 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.939 0.061 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.937 0.063 0.000
S50-S59 Injuries to the elbow and forearm
0.936 0.064 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.936 0.064 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.933 0.067 0.000
M10.99 Gout, unspecified (Site unspecified)
0.931 0.069 0.000
M65-M68 Disorders of synovium and tendon
0.931 0.069 0.000
Z98 Other postsurgical states
0.927 0.073 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.927 0.073 0.000
I05-I09 Chronic rheumatic heart diseases
0.925 0.075 0.000
Z80 Family history of malignant neoplasm
0.923 0.077 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.922 0.078 0.000
M80-M85 Disorders of bone density and structure
0.920 0.080 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.920 0.080 0.000
I51 Complications and ill-defined descriptions of heart disease
0.919 0.081 0.000
Z80.3 Family history of malignant neoplasm of breast
0.919 0.081 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.917 0.083 0.000
C77.3 Axillary and upper limb lymph nodes
0.915 0.085 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.915 0.085 0.000
C77.4 Inguinal and lower limb lymph nodes
0.910 0.090 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.909 0.091 0.000
I34 Nonrheumatic mitral valve disorders
0.906 0.094 0.000
O70 Perineal laceration during delivery
0.906 0.094 0.000
S52 Fracture of forearm
0.905 0.095 0.000
I77 Other disorders of arteries and arterioles
0.904 0.096 0.000
F10.0 Acute intoxication
0.900 0.100 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.899 0.101 0.000
O36.5 Maternal care for poor foetal growth
0.897 0.103 0.000
I46 Cardiac arrest
0.893 0.107 0.000
C50-C50 Malignant neoplasm of breast
0.892 0.108 0.000
Z88.2 Personal history of allergy to sulphonamides
0.891 0.109 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.890 0.110 0.000
I35 Nonrheumatic aortic valve disorders
0.890 0.110 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.890 0.110 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.889 0.111 0.000
I42 Cardiomyopathy
0.888 0.112 0.000
Z91.5 Personal history of self-harm
0.886 0.114 0.000
Z75 Problems related to medical facilities and other health care
0.885 0.115 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.885 0.115 0.000
H65-H75 Diseases of middle ear and mastoid
0.885 0.115 0.000
F10.3 Withdrawal state
0.885 0.115 0.000
I21 Acute myocardial infarction
0.884 0.116 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.883 0.117 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.883 0.117 0.000
M65 Synovitis and tenosynovitis
0.878 0.122 0.000
Z72 Problems related to lifestyle
0.875 0.125 0.000
I51.7 Cardiomegaly
0.873 0.127 0.000
D69 Purpura and other haemorrhagic conditions
0.871 0.129 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.870 0.130 0.000
O36.8 Maternal care for other specified foetal problems
0.870 0.130 0.000
O70.0 First degree perineal laceration during delivery
0.870 0.130 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.870 0.130 0.000
I95 Hypotension
0.869 0.131 0.000
Z60 Problems related to social environment
0.869 0.131 0.000
O80-O84 Delivery
0.867 0.133 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.865 0.135 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.864 0.136 0.000
O73 Retained placenta and membranes, without haemorrhage
0.864 0.136 0.000
M20-M25 Other joint disorders
0.864 0.136 0.000
W00-W19 Falls
0.864 0.136 0.000
O46.9 Antepartum haemorrhage, unspecified
0.864 0.136 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.863 0.137 0.000
S52.5 Fracture of lower end of radius
0.861 0.139 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.860 0.140 0.000
D69.6 Thrombocytopenia, unspecified
0.859 0.141 0.000
Y43 Primarily systemic agents
0.859 0.141 0.000
Z99.1 Dependence on respirator
0.857 0.143 0.000
F60-F69 Disorders of adult personality and behaviour
0.854 0.146 0.000
S60-S69 Injuries to the wrist and hand
0.854 0.146 0.000
I72 Other aneurysm
0.853 0.147 0.000
F41 Other anxiety disorders
0.852 0.148 0.000
Z99.3 Dependence on wheelchair
0.852 0.148 0.000
F30-F39 Mood [affective] disorders
0.851 0.149 0.000
Z98.8 Other specified postsurgical states
0.851 0.149 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.851 0.149 0.000
Z83 Family history of other specific disorders
0.848 0.152 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.848 0.152 0.000
I10-I15 Hypertensive diseases
0.848 0.152 0.000
I08 Multiple valve diseases
0.848 0.152 0.000
E83.4 Disorders of magnesium metabolism
0.846 0.154 0.000
F40 Phobic anxiety disorders
0.845 0.155 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.845 0.155 0.000
Chapter VI Diseases of the nervous system
0.844 0.156 0.000
Y52 Agents primarily affecting the cardiovascular system
0.844 0.156 0.000
F80-F89 Disorders of psychological development
0.843 0.157 0.000
Z72.1 Alcohol use
0.843 0.157 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.840 0.160 0.000
H90-H95 Other disorders of ear
0.840 0.160 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.837 0.163 0.000
I34.0 Mitral (valve) insufficiency
0.834 0.166 0.000
I25.5 Ischaemic cardiomyopathy
0.833 0.167 0.000
Z92.0 Personal history of contraception
0.832 0.168 0.000
C51-C58 Malignant neoplasms of female genital organs
0.832 0.168 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.832 0.168 0.000
S52.50 Fracture of lower end of radius (closed)
0.830 0.170 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.829 0.171 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.828 0.172 0.000
S10-S19 Injuries to the neck
0.826 0.174 0.000
S20-S29 Injuries to the thorax
0.824 0.176 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.824 0.176 0.000
T90 Sequelae of injuries of head
0.823 0.177 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.821 0.179 0.000
C50 Malignant neoplasm of breast
0.821 0.179 0.000
O41 Other disorders of amniotic fluid and membranes
0.817 0.183 0.000
T91 Sequelae of injuries of neck and trunk
0.816 0.184 0.000
Y44 Agents primarily affecting blood constituents
0.815 0.185 0.000
G90-G99 Other disorders of the nervous system
0.815 0.185 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.814 0.186 0.000
I50 Heart failure
0.814 0.186 0.000
Z63 Other problems related to primary support group, including family circumstances
0.814 0.186 0.000
Z71.9 Counselling, unspecified
0.813 0.187 0.000
Z60.2 Living alone
0.813 0.187 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.813 0.187 0.000
Z94 Transplanted organ and tissue status
0.811 0.189 0.000
C77.0 Lymph nodes of head, face and neck
0.811 0.189 0.000
T93 Sequelae of injuries of lower limb
0.811 0.189 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.811 0.189 0.000
O43 Placental disorders
0.810 0.190 0.000
O20 Haemorrhage in early pregnancy
0.810 0.190 0.000
I46.0 Cardiac arrest with successful resuscitation
0.810 0.190 0.000
O62 Abnormalities of forces of labour
0.810 0.190 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.808 0.192 0.000
E87.6 Hypokalaemia
0.808 0.192 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.805 0.195 0.000
H66 Suppurative and unspecified otitis media
0.804 0.196 0.000
M11 Other crystal arthropathies
0.803 0.197 0.000
O61 Failed induction of labour
0.801 0.199 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.799 0.201 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.798 0.202 0.000
M91-M94 Chondropathies
0.798 0.202 0.000
I77.1 Stricture of artery
0.793 0.207 0.000
I60-I69 Cerebrovascular diseases
0.792 0.208 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.789 0.211 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.787 0.213 0.000
Chapter VII Diseases of the eye and adnexa
0.786 0.214 0.000
M60-M63 Disorders of muscles
0.785 0.215 0.000
I95.1 Orthostatic hypotension
0.782 0.218 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.782 0.218 0.000
M23 Internal derangement of knee
0.782 0.218 0.000
E83.1 Disorders of iron metabolism
0.781 0.219 0.000
M10.96 Gout, unspecified (Lower leg)
0.781 0.219 0.000
Z29 Need for other prophylactic measures
0.781 0.219 0.000
Y84.0 Cardiac catheterisation
0.780 0.220 0.000
M45-M49 Spondylopathies
0.778 0.222 0.000
F40.2 Specific (isolated) phobias
0.778 0.222 0.000
I36 Nonrheumatic tricuspid valve disorders
0.778 0.222 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.777 0.223 0.000
W20-W49 Exposure to inanimate mechanical forces
0.777 0.223 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.777 0.223 0.000
O40 Polyhydramnios
0.776 0.224 0.000
O73.0 Retained placenta, without haemorrhage
0.776 0.224 0.000
D45 Polycythaemia vera
0.776 0.224 0.000
I71.0 Dissection of aorta [any part]
0.775 0.225 0.000
X20-X29 Contact with venomous animals and plants
0.773 0.227 0.000
I30 Acute pericarditis
0.773 0.227 0.000
F10.4 Withdrawal state with delirium
0.773 0.227 0.000
S52.8 Fracture of other parts of forearm
0.773 0.227 0.000
E40-E46 Malnutrition
0.772 0.228 0.000
H80-H83 Diseases of inner ear
0.772 0.228 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.771 0.229 0.000
I08.0 Disorders of both mitral and aortic valves
0.771 0.229 0.000
C50.1 Central portion of breast
0.770 0.230 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.769 0.231 0.000
C79.2 Secondary malignant neoplasm of skin
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
Z87 Personal history of other diseases and conditions
0.768 0.232 0.000
I25.2 Old myocardial infarction
0.768 0.232 0.000
M00-M03 Infectious arthropathies
0.767 0.233 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.767 0.233 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.764 0.236 0.000
Z73 Problems related to life-management difficulty
0.763 0.237 0.000
I95.9 Hypotension, unspecified
0.763 0.237 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.763 0.237 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.763 0.237 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.762 0.238 0.000
M85 Other disorders of bone density and structure
0.761 0.239 0.000
H92 Otalgia and effusion of ear
0.761 0.239 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.760 0.240 0.000
M25 Other joint disorders, not elsewhere classified
0.760 0.240 0.000
I12 Hypertensive renal disease
0.759 0.241 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.758 0.242 0.000
Z88.0 Personal history of allergy to penicillin
0.758 0.242 0.000
O80 Single spontaneous delivery
0.757 0.243 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.756 0.244 0.000
Z83.3 Family history of diabetes mellitus
0.755 0.245 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.755 0.245 0.000
T59 Toxic effect of other gases, fumes and vapours
0.754 0.246 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.754 0.246 0.000
M80 Osteoporosis with pathological fracture
0.753 0.247 0.000
Z92.8 Personal history of other medical treatment
0.753 0.247 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.751 0.249 0.000
E83.5 Disorders of calcium metabolism
0.751 0.249 0.000
Z95.2 Presence of prosthetic heart valve
0.751 0.249 0.000
V80-V89 Other land transport accidents
0.750 0.250 0.000
I74 Arterial embolism and thrombosis
0.750 0.250 0.000
Chapter I Certain infectious and parasitic diseases
0.750 0.250 0.000
F60 Specific personality disorders
0.750 0.250 0.000
O00-O08 Pregnancy with abortive outcome
0.750 0.250 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.749 0.251 0.000
H74 Other disorders of middle ear and mastoid
0.747 0.253 0.000
C80 Malignant neoplasm without specification of site
0.747 0.253 0.000
I70 Atherosclerosis
0.746 0.254 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.746 0.254 0.000
Z99.2 Dependence on renal dialysis
0.745 0.255 0.000
O23 Infections of genito-urinary tract in pregnancy
0.745 0.255 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.744 0.256 0.000
Z96 Presence of other functional implants
0.744 0.256 0.000
Y43.3 Other antineoplastic drugs
0.742 0.258 0.000
C77.8 Lymph nodes of multiple regions
0.742 0.258 0.000
E20-E35 Disorders of other endocrine glands
0.742 0.258 0.000
Z74 Problems related to care-provider dependency
0.742 0.258 0.000
V10-V19 Pedal cyclist injured in transport accident
0.742 0.258 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.741 0.258 0.000
I05 Rheumatic mitral valve diseases
0.741 0.259 0.000
Z95.4 Presence of other heart-valve replacement
0.740 0.260 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.740 0.260 0.000
M24 Other specific joint derangements
0.740 0.260 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.739 0.261 0.000
M81 Osteoporosis without pathological fracture
0.739 0.261 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.739 0.261 0.000
M05 Seropositive rheumatoid arthritis
0.737 0.263 0.000
G95 Other diseases of spinal cord
0.737 0.263 0.000
M66 Spontaneous rupture of synovium and tendon
0.737 0.263 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.737 0.263 0.000
X60-X84 Intentional self-harm
0.737 0.263 0.000
E87.5 Hyperkalaemia
0.737 0.263 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.264 0.000
I51.0 Cardiac septal defect, acquired
0.736 0.264 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.735 0.265 0.000
W19 Unspecified fall
0.735 0.265 0.000
M65.3 Trigger finger
0.735 0.265 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.734 0.266 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.733 0.267 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.732 0.268 0.000
I60 Subarachnoid haemorrhage
0.732 0.268 0.000
F81 Specific developmental disorders of scholastic skills
0.730 0.270 0.000
C56 Malignant neoplasm of ovary
0.730 0.270 0.000
O44 Placenta praevia
0.729 0.271 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
E00-E07 Disorders of thyroid gland
0.729 0.271 0.000
I42.0 Dilated cardiomyopathy
0.728 0.272 0.000
T92 Sequelae of injuries of upper limb
0.727 0.273 0.000
I78 Diseases of capillaries
0.726 0.274 0.000
I50.1 Left ventricular failure
0.726 0.274 0.000
O16 Unspecified maternal hypertension
0.725 0.274 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.725 0.275 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.725 0.275 0.000
C45 Mesothelioma
0.725 0.275 0.000
O42 Premature rupture of membranes
0.724 0.276 0.000
E16 Other disorders of pancreatic internal secretion
0.723 0.277 0.000
Y84.6 Urinary catheterisation
0.723 0.277 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.720 0.280 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.720 0.280 0.000
M84 Disorders of continuity of bone
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.719 0.281 0.000
I12.0 Hypertensive renal disease with renal failure
0.719 0.281 0.000
R00 Abnormalities of heart beat
0.719 0.281 0.000
I21.4 Acute subendocardial myocardial infarction
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
Z80.6 Family history of leukaemia
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.716 0.284 0.000
F10.9 Unspecified mental and behavioural disorder
0.715 0.284 0.000
F10.8 Other mental and behavioural disorders
0.715 0.284 0.000
F10.7 Residual and late-onset psychotic disorder
0.715 0.284 0.000
F10.6 Amnesic syndrome
0.715 0.284 0.000
F10.5 Psychotic disorder
0.715 0.284 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.715 0.284 0.000
E83.3 Disorders of phosphorus metabolism
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I77.8 Other specified disorders of arteries and arterioles
0.715 0.285 0.000
M23.8 Other internal derangements of knee
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.714 0.286 0.000
H66.9 Otitis media, unspecified
0.714 0.286 0.000
M07 Psoriatic and enteropathic arthropathies
0.714 0.286 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.713 0.287 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.713 0.287 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
I35.0 Aortic (valve) stenosis
0.712 0.288 0.000
I25.3 Aneurysm of heart
0.712 0.288 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.712 0.288 0.000
I42.2 Other hypertrophic cardiomyopathy
0.711 0.288 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
O45 Premature separation of placenta [abruptio placentae]
0.710 0.290 0.000
O33 Maternal care for known or suspected disproportion
0.710 0.290 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.710 0.290 0.000
O31 Complications specific to multiple gestation
0.710 0.290 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
Z89 Acquired absence of limb
0.710 0.290 0.000
Z36 Antenatal screening
0.710 0.290 0.000
Y57 Other and unspecified drugs and medicaments
0.709 0.291 0.000
O74 Complications of anaesthesia during labour and delivery
0.708 0.292 0.000
O71 Other obstetric trauma
0.708 0.292 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.708 0.292 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.708 0.292 0.000
O60 Preterm delivery
0.708 0.292 0.000
Y44.2 Anticoagulants
0.708 0.292 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.708 0.292 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.707 0.293 0.000
T39.0 Salicylates
0.707 0.293 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.707 0.293 0.000
Y84.8 Other medical procedures
0.706 0.294 0.000
Z76 Persons encountering health services in other circumstances
0.706 0.294 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.706 0.294 0.000
T31 Burns classified according to extent of body surface involved
0.705 0.295 0.000
O75.0 Maternal distress during labour and delivery
0.703 0.297 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.703 0.297 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.703 0.297 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.703 0.297 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.703 0.297 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.703 0.297 0.000
E87.0 Hyperosmolality and hypernatraemia
0.702 0.298 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.702 0.298 0.000
F32 Depressive episode
0.702 0.298 0.000
S19 Other and unspecified injuries of neck
0.702 0.298 0.000
Q23 Congenital malformations of aortic and mitral valves
0.702 0.298 0.000
Y43.0 Antiallergic and antiemetic drugs
0.701 0.298 0.000
Z29.2 Other prophylactic chemotherapy
0.701 0.299 0.000
I38 Endocarditis, valve unspecified
0.701 0.299 0.000
R00.2 Palpitations
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.699 0.301 0.000
M12 Other specific arthropathies
0.699 0.301 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.699 0.301 0.000
M08 Juvenile arthritis
0.699 0.301 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.699 0.301 0.000
H52 Disorders of refraction and accommodation
0.698 0.302 0.000
F41.2 Mixed anxiety and depressive disorder
0.698 0.302 0.000
I45 Other conduction disorders
0.697 0.303 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.696 0.304 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.696 0.304 0.000
R00.0 Tachycardia, unspecified
0.695 0.305 0.000
Y84.2 Radiological procedure and radiotherapy
0.695 0.305 0.000
S60 Superficial injury of wrist and hand
0.695 0.305 0.000
E87.3 Alkalosis
0.695 0.305 0.000
Z88.6 Personal history of allergy to analgesic agent
0.693 0.307 0.000
C77.2 Intra-abdominal lymph nodes
0.693 0.307 0.000
Q24 Other congenital malformations of heart
0.693 0.307 0.000
Q80-Q89 Other congenital malformations
0.692 0.308 0.000
I44 Atrioventricular and left bundle-branch block
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.308 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.692 0.308 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.308 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
T36 Poisoning by systemic antibiotics
0.692 0.308 0.000
Z63.4 Disappearance and death of family member
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.691 0.309 0.000
Y58 Bacterial vaccines
0.691 0.309 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.691 0.309 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.691 0.309 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.691 0.309 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.691 0.309 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.691 0.309 0.000
Y48 Anaesthetics and therapeutic gases
0.691 0.309 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.691 0.309 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.691 0.309 0.000
O21 Excessive vomiting in pregnancy
0.691 0.309 0.000
F33 Recurrent depressive disorder
0.691 0.309 0.000
S64 Injury of nerves at wrist and hand level
0.691 0.309 0.000
E89.2 Postprocedural hypoparathyroidism
0.691 0.309 0.000
V20-V29 Motorcycle rider injured in transport accident
0.690 0.310 0.000
T91.1 Sequelae of fracture of spine
0.690 0.310 0.000
D69.5 Secondary thrombocytopenia
0.689 0.311 0.000
E89.0 Postprocedural hypothyroidism
0.689 0.311 0.000
I42.9 Cardiomyopathy, unspecified
0.689 0.311 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.688 0.312 0.000
O41.0 Oligohydramnios
0.688 0.312 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.688 0.312 0.000
M10.4 Other secondary gout
0.687 0.313 0.000
M10.3 Gout due to impairment of renal function
0.687 0.313 0.000
M10.2 Drug-induced gout
0.687 0.313 0.000
M10.1 Lead-induced gout
0.687 0.313 0.000
M10.0 Idiopathic gout
0.687 0.313 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.687 0.313 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.686 0.314 0.000
Z37 Outcome of delivery
0.686 0.314 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.686 0.314 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.686 0.314 0.000
Y84.1 Kidney dialysis
0.685 0.315 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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