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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115023769
log Bayes Factor = 14.1062
Chromosome 3   position 153,241,084  (GRCh37) Explore rs115023769 on Ensembl!
Variant rs115023769 is part of Cluster X0209

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
K55-K64 Other diseases of intestines
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
M80-M85 Disorders of bone density and structure
0.989 0.011 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.986 0.014 0.000
K58 Irritable bowel syndrome
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.981 0.019 0.000
D69 Purpura and other haemorrhagic conditions
0.980 0.020 0.000
M81 Osteoporosis without pathological fracture
0.979 0.021 0.000
Chapter X Diseases of the respiratory system
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.976 0.024 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.975 0.025 0.000
D69.6 Thrombocytopenia, unspecified
0.973 0.027 0.000
K70-K77 Diseases of liver
0.972 0.028 0.000
M81.9 Osteoporosis, unspecified
0.970 0.030 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.968 0.032 0.000
H35 Other retinal disorders
0.965 0.035 0.000
K50-K52 Noninfective enteritis and colitis
0.963 0.037 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.955 0.045 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.955 0.045 0.000
K55 Vascular disorders of intestine
0.952 0.048 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.949 0.051 0.000
K56.2 Volvulus
0.948 0.052 0.000
Chapter XIV Diseases of the genitourinary system
0.947 0.053 0.000
E70-E90 Metabolic disorders
0.946 0.054 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.944 0.056 0.000
M86-M90 Other osteopathies
0.944 0.056 0.000
H35.8 Other specified retinal disorders
0.944 0.056 0.000
I84 Haemorrhoids
0.944 0.056 0.000
M05-M14 Inflammatory polyarthropathies
0.943 0.057 0.000
N17-N19 Renal failure
0.941 0.059 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.937 0.063 0.000
J90-J94 Other diseases of pleura
0.935 0.065 0.000
K60 Fissure and fistula of anal and rectal regions
0.935 0.065 0.000
I84.6 Residual haemorrhoidal skin tags
0.935 0.065 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.932 0.068 0.000
M45-M49 Spondylopathies
0.928 0.072 0.000
E83 Disorders of mineral metabolism
0.926 0.074 0.000
K50 Crohn's disease [regional enteritis]
0.926 0.074 0.000
Chapter I Certain infectious and parasitic diseases
0.922 0.078 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.911 0.089 0.000
H34 Retinal vascular occlusions
0.911 0.089 0.000
H33 Retinal detachments and breaks
0.904 0.096 0.000
K86 Other diseases of pancreas
0.903 0.097 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.901 0.099 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.900 0.100 0.000
K90-K93 Other diseases of the digestive system
0.899 0.101 0.000
D70 Agranulocytosis
0.898 0.102 0.000
L20-L30 Dermatitis and eczema
0.894 0.106 0.000
K76 Other diseases of liver
0.892 0.108 0.000
I84.9 Unspecified haemorrhoids without complication
0.891 0.109 0.000
N18 Chronic renal failure
0.887 0.113 0.000
I95 Hypotension
0.887 0.113 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.887 0.113 0.000
E83.5 Disorders of calcium metabolism
0.883 0.117 0.000
K83 Other diseases of biliary tract
0.882 0.118 0.000
S20-S29 Injuries to the thorax
0.882 0.118 0.000
N19 Unspecified renal failure
0.881 0.119 0.000
M89 Other disorders of bone
0.881 0.119 0.000
J90 Pleural effusion, not elsewhere classified
0.879 0.121 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.879 0.121 0.000
K70 Alcoholic liver disease
0.878 0.122 0.000
K60.2 Anal fissure, unspecified
0.878 0.122 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.876 0.124 0.000
S90-S99 Injuries to the ankle and foot
0.876 0.124 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.871 0.129 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.870 0.130 0.000
K55.2 Angiodysplasia of colon
0.868 0.132 0.000
K51 Ulcerative colitis
0.865 0.135 0.000
K92 Other diseases of digestive system
0.864 0.136 0.000
K74 Fibrosis and cirrhosis of liver
0.858 0.142 0.000
H53-H54 Visual disturbances and blindness
0.858 0.142 0.000
N60-N64 Disorders of breast
0.858 0.142 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.854 0.146 0.000
M48 Other spondylopathies
0.853 0.147 0.000
M20-M25 Other joint disorders
0.852 0.148 0.000
M81.98 Osteoporosis, unspecified (Other)
0.849 0.151 0.000
S00-S09 Injuries to the head
0.848 0.152 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.846 0.154 0.000
K50.8 Other Crohn's disease
0.844 0.156 0.000
J40-J47 Chronic lower respiratory diseases
0.843 0.157 0.000
K83.8 Other specified diseases of biliary tract
0.842 0.158 0.000
N17 Acute renal failure
0.841 0.159 0.000
M15-M19 Arthrosis
0.841 0.159 0.000
N18.5 Chronic kidney disease, stage 5
0.840 0.160 0.000
N63 Unspecified lump in breast
0.836 0.164 0.000
E87.7 Fluid overload
0.836 0.164 0.000
H18 Other disorders of cornea
0.836 0.164 0.000
B35-B49 Mycoses
0.835 0.165 0.000
N00-N08 Glomerular diseases
0.834 0.166 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.831 0.169 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.831 0.169 0.000
K55.9 Vascular disorder of intestine, unspecified
0.830 0.170 0.000
I87 Other disorders of veins
0.830 0.170 0.000
K92.1 Melaena
0.829 0.171 0.000
K50.1 Crohn's disease of large intestine
0.828 0.172 0.000
J93 Pneumothorax
0.827 0.173 0.000
H33.0 Retinal detachment with retinal break
0.824 0.176 0.000
H43-H45 Disorders of vitreous body and globe
0.821 0.179 0.000
M07 Psoriatic and enteropathic arthropathies
0.819 0.181 0.000
M13 Other arthritis
0.819 0.181 0.000
M89.9 Disorder of bone, unspecified
0.817 0.183 0.000
L40-L45 Papulosquamous disorders
0.814 0.186 0.000
I85 Oesophageal varices
0.814 0.186 0.000
L50-L54 Urticaria and erythema
0.812 0.188 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.812 0.188 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.811 0.189 0.000
H34.8 Other retinal vascular occlusions
0.811 0.189 0.000
E87.5 Hyperkalaemia
0.808 0.192 0.000
L29 Pruritus
0.802 0.198 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.802 0.198 0.000
S20 Superficial injury of thorax
0.801 0.199 0.000
I86 Varicose veins of other sites
0.799 0.201 0.000
M48.0 Spinal stenosis
0.799 0.201 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.799 0.201 0.000
M65-M68 Disorders of synovium and tendon
0.797 0.203 0.000
Q60-Q64 Congenital malformations of the urinary system
0.796 0.203 0.000
M40-M43 Deforming dorsopathies
0.796 0.204 0.000
S70-S79 Injuries to the hip and thigh
0.796 0.204 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.796 0.204 0.000
J95-J99 Other diseases of the respiratory system
0.795 0.205 0.000
E20-E35 Disorders of other endocrine glands
0.794 0.205 0.000
M47 Spondylosis
0.794 0.206 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.792 0.208 0.000
K76.6 Portal hypertension
0.791 0.209 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.786 0.214 0.000
M06 Other rheumatoid arthritis
0.786 0.214 0.000
K60.1 Chronic anal fissure
0.786 0.214 0.000
D68 Other coagulation defects
0.785 0.215 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.783 0.217 0.000
T86 Failure and rejection of transplanted organs and tissues
0.783 0.217 0.000
N72 Inflammatory disease of cervix uteri
0.783 0.217 0.000
M19 Other arthrosis
0.781 0.219 0.000
E83.1 Disorders of iron metabolism
0.780 0.220 0.000
K86.1 Other chronic pancreatitis
0.776 0.224 0.000
L30 Other dermatitis
0.776 0.224 0.000
K56.4 Other impaction of intestine
0.775 0.225 0.000
J30-J39 Other diseases of upper respiratory tract
0.774 0.226 0.000
M81.4 Drug-induced osteoporosis
0.773 0.227 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.772 0.228 0.000
H18.5 Hereditary corneal dystrophies
0.771 0.229 0.000
T88.4 Failed or difficult intubation
0.771 0.229 0.000
M85 Other disorders of bone density and structure
0.770 0.230 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.769 0.231 0.000
J40 Bronchitis, not specified as acute or chronic
0.767 0.233 0.000
E40-E46 Malnutrition
0.766 0.234 0.000
M84 Disorders of continuity of bone
0.766 0.234 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.764 0.236 0.000
K04 Diseases of pulp and periapical tissues
0.764 0.236 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.764 0.236 0.000
H35.9 Retinal disorder, unspecified
0.764 0.236 0.000
M35 Other systemic involvement of connective tissue
0.763 0.237 0.000
L29.9 Pruritus, unspecified
0.763 0.237 0.000
M82 Osteoporosis in diseases classified elsewhere
0.763 0.237 0.000
M21 Other acquired deformities of limbs
0.763 0.237 0.000
M18 Arthrosis of first carpometacarpal joint
0.762 0.238 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.762 0.238 0.000
J47 Bronchiectasis
0.761 0.239 0.000
S00 Superficial injury of head
0.760 0.240 0.000
I82 Other venous embolism and thrombosis
0.760 0.240 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.759 0.241 0.000
D69.5 Secondary thrombocytopenia
0.759 0.241 0.000
H34.2 Other retinal artery occlusions
0.759 0.241 0.000
I84.5 External haemorrhoids without complication
0.756 0.244 0.000
K12 Stomatitis and related lesions
0.755 0.245 0.000
T18 Foreign body in alimentary tract
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.753 0.247 0.000
N17.9 Acute renal failure, unspecified
0.752 0.248 0.000
M19.0 Primary arthrosis of other joints
0.751 0.249 0.000
M90 Osteopathies in diseases classified elsewhere
0.751 0.249 0.000
H35.0 Background retinopathy and retinal vascular changes
0.750 0.250 0.000
E83.3 Disorders of phosphorus metabolism
0.750 0.250 0.000
I95.1 Orthostatic hypotension
0.750 0.250 0.000
J09-J18 Influenza and pneumonia
0.749 0.251 0.000
I95.2 Hypotension due to drugs
0.749 0.251 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.749 0.251 0.000
I95.9 Hypotension, unspecified
0.748 0.252 0.000
K86.8 Other specified diseases of pancreas
0.748 0.252 0.000
J60-J70 Lung diseases due to external agents
0.747 0.253 0.000
B99-B99 Other infectious diseases
0.746 0.253 0.000
I77 Other disorders of arteries and arterioles
0.746 0.254 0.000
K76.9 Liver disease, unspecified
0.746 0.254 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.746 0.254 0.000
K50.9 Crohn's disease, unspecified
0.746 0.254 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.746 0.254 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.745 0.255 0.000
E78.5 Hyperlipidaemia, unspecified
0.744 0.256 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.743 0.257 0.000
M48.02 Spinal stenosis (Cervical region)
0.743 0.257 0.000
H53 Visual disturbances
0.743 0.257 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.742 0.258 0.000
H36 Retinal disorders in diseases classified elsewhere
0.742 0.258 0.000
H40-H42 Glaucoma
0.741 0.259 0.000
B37 Candidiasis
0.741 0.259 0.000
K70.3 Alcoholic cirrhosis of liver
0.740 0.260 0.000
H35.2 Other proliferative retinopathy
0.740 0.260 0.000
K74.6 Other and unspecified cirrhosis of liver
0.739 0.261 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.738 0.262 0.000
L40 Psoriasis
0.738 0.262 0.000
S10-S19 Injuries to the neck
0.735 0.265 0.000
D72 Other disorders of white blood cells
0.733 0.267 0.000
H33.1 Retinoschisis and retinal cysts
0.732 0.268 0.000
I89.0 Lymphoedema, not elsewhere classified
0.732 0.268 0.000
M07.3 Other psoriatic arthropathies
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
K55.0 Acute vascular disorders of intestine
0.729 0.271 0.000
N18.0 End-stage renal disease
0.728 0.271 0.000
H35.5 Hereditary retinal dystrophy
0.728 0.272 0.000
J94 Other pleural conditions
0.728 0.272 0.000
H35.7 Separation of retinal layers
0.728 0.272 0.000
M24 Other specific joint derangements
0.727 0.272 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.727 0.273 0.000
K70.9 Alcoholic liver disease, unspecified
0.726 0.274 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.726 0.274 0.000
K86.3 Pseudocyst of pancreas
0.726 0.274 0.000
N18.4 Chronic kidney disease, stage 4
0.725 0.275 0.000
H33.4 Traction detachment of retina
0.725 0.275 0.000
H35.6 Retinal haemorrhage
0.725 0.275 0.000
T87 Complications peculiar to reattachment and amputation
0.724 0.276 0.000
K86.9 Disease of pancreas, unspecified
0.724 0.276 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.722 0.278 0.000
M47.9 Spondylosis, unspecified
0.720 0.280 0.000
M13.9 Arthritis, unspecified
0.720 0.280 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.719 0.281 0.000
S90 Superficial injury of ankle and foot
0.719 0.281 0.000
K74.0 Hepatic fibrosis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
T63 Toxic effect of contact with venomous animals
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
E78.2 Mixed hyperlipidaemia
0.716 0.284 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.715 0.285 0.000
S06 Intracranial injury
0.715 0.285 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.714 0.285 0.000
T81 Complications of procedures, not elsewhere classified
0.714 0.286 0.000
H53.9 Visual disturbance, unspecified
0.713 0.287 0.000
K02 Dental caries
0.712 0.288 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.712 0.288 0.000
H31 Other disorders of choroid
0.712 0.288 0.000
H30 Chorioretinal inflammation
0.712 0.288 0.000
K73 Chronic hepatitis, not elsewhere classified
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
N10-N16 Renal tubulo-interstitial diseases
0.711 0.289 0.000
Chapter VI Diseases of the nervous system
0.711 0.289 0.000
T51 Toxic effect of alcohol
0.711 0.289 0.000
M83 Adult osteomalacia
0.709 0.291 0.000
M31 Other necrotising vasculopathies
0.709 0.291 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.707 0.293 0.000
D67 Hereditary factor IX deficiency
0.707 0.293 0.000
D66 Hereditary factor VIII deficiency
0.707 0.293 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.707 0.293 0.000
I85.9 Oesophageal varices without bleeding
0.706 0.294 0.000
I84.0 Internal thrombosed haemorrhoids
0.706 0.294 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
E73 Lactose intolerance
0.706 0.294 0.000
M89.8 Other specified disorders of bone
0.705 0.295 0.000
T42.4 Benzodiazepines
0.705 0.295 0.000
S50-S59 Injuries to the elbow and forearm
0.705 0.295 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.705 0.295 0.000
J32 Chronic sinusitis
0.705 0.295 0.000
M87 Osteonecrosis
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
S99 Other and unspecified injuries of ankle and foot
0.704 0.296 0.000
K10 Other diseases of jaws
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.703 0.297 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.703 0.297 0.000
M91-M94 Chondropathies
0.703 0.297 0.000
K51.8 Other ulcerative colitis
0.703 0.297 0.000
D69.9 Haemorrhagic condition, unspecified
0.703 0.297 0.000
D69.8 Other specified haemorrhagic conditions
0.703 0.297 0.000
D69.4 Other primary thrombocytopenia
0.703 0.297 0.000
D69.2 Other nonthrombocytopenic purpura
0.703 0.297 0.000
D69.1 Qualitative platelet defects
0.703 0.297 0.000
D69.0 Allergic purpura
0.703 0.297 0.000
M81.8 Other osteoporosis
0.702 0.298 0.000
M81.6 Localised osteoporosis [Lequesne]
0.702 0.298 0.000
M81.5 Idiopathic osteoporosis
0.702 0.298 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.702 0.298 0.000
M81.2 Osteoporosis of disuse
0.702 0.298 0.000
M81.1 Postoophorectomy osteoporosis
0.702 0.298 0.000
M81.0 Postmenopausal osteoporosis
0.702 0.298 0.000
M86 Osteomyelitis
0.702 0.298 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.701 0.299 0.000
H55-H59 Other disorders of eye and adnexa
0.701 0.299 0.000
L30.9 Dermatitis, unspecified
0.700 0.300 0.000
Chapter XX External causes of morbidity and mortality
0.700 0.300 0.000
L10-L14 Bullous disorders
0.700 0.300 0.000
Q61 Cystic kidney disease
0.698 0.302 0.000
K77 Liver disorders in diseases classified elsewhere
0.697 0.303 0.000
K71 Toxic liver disease
0.697 0.303 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.696 0.304 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.695 0.305 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.695 0.305 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.695 0.305 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.695 0.305 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.695 0.305 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.695 0.305 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.695 0.305 0.000
B00 Herpesviral [herpes simplex] infections
0.695 0.305 0.000
K31 Other diseases of stomach and duodenum
0.695 0.305 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.695 0.305 0.000
K65-K67 Diseases of peritoneum
0.695 0.305 0.000
K51.4 Pseudopolyposis of colon
0.695 0.305 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.694 0.306 0.000
I88 Nonspecific lymphadenitis
0.694 0.306 0.000
K61 Abscess of anal and rectal regions
0.693 0.307 0.000
K82 Other diseases of gallbladder
0.693 0.307 0.000
K31.8 Other specified diseases of stomach and duodenum
0.692 0.308 0.000
H35.1 Retinopathy of prematurity
0.692 0.308 0.000
H16 Keratitis
0.691 0.309 0.000
M11 Other crystal arthropathies
0.691 0.309 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.690 0.310 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.690 0.310 0.000
T82.3 Mechanical complication of other vascular grafts
0.690 0.310 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.690 0.310 0.000
K56.1 Intussusception
0.689 0.311 0.000
E83.4 Disorders of magnesium metabolism
0.689 0.311 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.688 0.312 0.000
I99 Other and unspecified disorders of circulatory system
0.687 0.312 0.000
K56.3 Gallstone ileus
0.687 0.312 0.000
K56.0 Paralytic ileus
0.687 0.312 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.687 0.313 0.000
H21 Other disorders of iris and ciliary body
0.687 0.313 0.000
T58 Toxic effect of carbon monoxide
0.687 0.313 0.000
E88 Other metabolic disorders
0.685 0.315 0.000
N02 Recurrent and persistent haematuria
0.685 0.315 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.684 0.316 0.000
K70.1 Alcoholic hepatitis
0.683 0.317 0.000
J42 Unspecified chronic bronchitis
0.683 0.317 0.000
K55.8 Other vascular disorders of intestine
0.683 0.317 0.000
K55.1 Chronic vascular disorders of intestine
0.683 0.317 0.000
L60-L75 Disorders of skin appendages
0.682 0.318 0.000
N61 Inflammatory disorders of breast
0.681 0.319 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.680 0.320 0.000
E85 Amyloidosis
0.678 0.322 0.000
E84 Cystic fibrosis
0.678 0.322 0.000
E79 Disorders of purine and pyrimidine metabolism
0.678 0.322 0.000
E77 Disorders of glycoprotein metabolism
0.678 0.322 0.000
E76 Disorders of glycosaminoglycan metabolism
0.678 0.322 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.678 0.322 0.000
E74 Other disorders of carbohydrate metabolism
0.678 0.322 0.000
E72 Other disorders of amino-acid metabolism
0.678 0.322 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.678 0.322 0.000
E70 Disorders of aromatic amino-acid metabolism
0.678 0.322 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.678 0.322 0.000
Q50-Q56 Congenital malformations of genital organs
0.678 0.322 0.000
B44 Aspergillosis
0.678 0.322 0.000
J93.9 Pneumothorax, unspecified
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.677 0.323 0.000
M14 Arthropathies in other diseases classified elsewhere
0.676 0.324 0.000
M12 Other specific arthropathies
0.676 0.324 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.676 0.324 0.000
M08 Juvenile arthritis
0.676 0.324 0.000
S92 Fracture of foot, except ankle
0.675 0.325 0.000
T17 Foreign body in respiratory tract
0.675 0.325 0.000
I84.3 External thrombosed haemorrhoids
0.675 0.325 0.000
K51.5 Mucosal proctocolitis
0.674 0.326 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.673 0.327 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.671 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.671 0.328 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.671 0.329 0.000
E65-E68 Obesity and other hyperalimentation
0.671 0.329 0.000
S72 Fracture of femur
0.671 0.329 0.000
K60.5 Anorectal fistula
0.670 0.329 0.000
K60.4 Rectal fistula
0.670 0.329 0.000
K60.0 Acute anal fissure
0.670 0.329 0.000
K04.7 Periapical abscess without sinus
0.671 0.329 0.000
M13.98 Arthritis, unspecified (Other)
0.670 0.330 0.000
I10-I15 Hypertensive diseases
0.670 0.330 0.000
J93.0 Spontaneous tension pneumothorax
0.670 0.330 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.669 0.331 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.668 0.332 0.000
D74 Methaemoglobinaemia
0.668 0.332 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.668 0.332 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.668 0.332 0.000
S27 Injury of other and unspecified intrathoracic organs
0.667 0.332 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.666 0.334 0.000
M49 Spondylopathies in diseases classified elsewhere
0.665 0.335 0.000
M45 Ankylosing spondylitis
0.665 0.335 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.664 0.336 0.000
E83.8 Other disorders of mineral metabolism
0.664 0.336 0.000
E83.2 Disorders of zinc metabolism
0.664 0.336 0.000
E83.0 Disorders of copper metabolism
0.664 0.336 0.000
H35.4 Peripheral retinal degeneration
0.663 0.337 0.000
J81 Pulmonary oedema
0.662 0.338 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.662 0.338 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.662 0.338 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.661 0.339 0.000
B65-B83 Helminthiases
0.661 0.339 0.000
B50-B64 Protozoal diseases
0.661 0.339 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.661 0.339 0.000
A75-A79 Rickettsioses
0.661 0.339 0.000
A70-A74 Other diseases caused by chlamydiae
0.661 0.339 0.000
A65-A69 Other spirochaetal diseases
0.661 0.339 0.000
A20-A28 Certain zoonotic bacterial diseases
0.661 0.339 0.000
A15-A19 Tuberculosis
0.661 0.339 0.000
M35.3 Polymyalgia rheumatica
0.661 0.339 0.000
T79-T79 Certain early complications of trauma
0.660 0.340 0.000
N05 Unspecified nephritic syndrome
0.660 0.340 0.000
K83.1 Obstruction of bile duct
0.660 0.340 0.000
A30-A49 Other bacterial diseases
0.660 0.340 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.660 0.340 0.000
I05-I09 Chronic rheumatic heart diseases
0.660 0.340 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.659 0.341 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.659 0.341 0.000
M10 Gout
0.659 0.341 0.000
E21.0 Primary hyperparathyroidism
0.658 0.342 0.000
M41 Scoliosis
0.657 0.343 0.000
L50 Urticaria
0.657 0.343 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.656 0.344 0.000
H44 Disorders of globe
0.656 0.344 0.000
M88 Paget's disease of bone [osteitis deformans]
0.656 0.344 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.656 0.344 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.653 0.346 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.653 0.346 0.000
H17 Corneal scars and opacities
0.653 0.346 0.000
H15 Disorders of sclera
0.653 0.346 0.000
I87.1 Compression of vein
0.654 0.346 0.000
H34.9 Retinal vascular occlusion, unspecified
0.653 0.347 0.000
H34.1 Central retinal artery occlusion
0.653 0.347 0.000
H34.0 Transient retinal artery occlusion
0.653 0.347 0.000
Q80-Q89 Other congenital malformations
0.653 0.347 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.652 0.347 0.000
M06.3 Rheumatoid nodule
0.652 0.348 0.000
J92 Pleural plaque
0.652 0.348 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.651 0.349 0.000
N17.0 Acute renal failure with tubular necrosis
0.651 0.349 0.000
I77.6 Arteritis, unspecified
0.651 0.349 0.000
E78.4 Other hyperlipidaemia
0.651 0.349 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.651 0.349 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.651 0.349 0.000
H54 Blindness and low vision
0.650 0.350 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.650 0.350 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.650 0.350 0.000
H33.5 Other retinal detachments
0.648 0.351 0.000
A80-A89 Viral infections of the central nervous system
0.648 0.352 0.000
K72 Hepatic failure, not elsewhere classified
0.647 0.353 0.000
H33.3 Retinal breaks without detachment
0.647 0.353 0.000
K20 Oesophagitis
0.646 0.354 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.646 0.354 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.646 0.354 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.646 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
T36 Poisoning by systemic antibiotics
0.646 0.354 0.000
H10-H13 Disorders of conjunctiva
0.646 0.354 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.646 0.354 0.000
D73 Diseases of spleen
0.646 0.354 0.000
E78.8 Other disorders of lipoprotein metabolism
0.646 0.354 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.645 0.354 0.000
Q35-Q37 Cleft lip and cleft palate
0.645 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.645 0.354 0.000
S40-S49 Injuries to the shoulder and upper arm
0.645 0.354 0.000
J93.1 Other spontaneous pneumothorax
0.645 0.355 0.000
M48.09 Spinal stenosis (Site unspecified)
0.645 0.355 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.645 0.355 0.000
T66-T78 Other and unspecified effects of external causes
0.644 0.356 0.000
H43 Disorders of vitreous body
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.641 0.358 0.000
L25 Unspecified contact dermatitis
0.641 0.359 0.000
L24 Irritant contact dermatitis
0.641 0.359 0.000
L23 Allergic contact dermatitis
0.641 0.359 0.000
L21 Seborrhoeic dermatitis
0.641 0.359 0.000
L20 Atopic dermatitis
0.641 0.359 0.000
L26 Exfoliative dermatitis
0.641 0.359 0.000
L22 Diaper [napkin] dermatitis
0.641 0.359 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.641 0.359 0.000
A63.0 Anogenital (venereal) warts
0.640 0.360 0.000
K76.7 Hepatorenal syndrome
0.640 0.360 0.000
K76.5 Hepatic veno-occlusive disease
0.640 0.360 0.000
K76.4 Peliosis hepatis
0.640 0.360 0.000
K76.3 Infarction of liver
0.640 0.360 0.000
K76.2 Central haemorrhagic necrosis of liver
0.640 0.360 0.000
K76.1 Chronic passive congestion of liver
0.640 0.360 0.000
B37.3 Candidiasis of vulva and vagina
0.639 0.361 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.638 0.362 0.000
G62 Other polyneuropathies
0.638 0.362 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.638 0.362 0.000
K07 Dentofacial anomalies [including malocclusion]
0.637 0.363 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.637 0.363 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.637 0.363 0.000
L53 Other erythematous conditions
0.637 0.363 0.000
N18.3 Chronic kidney disease, stage 3
0.637 0.363 0.000
I86.4 Gastric varices
0.637 0.363 0.000
N18.8 Other chronic renal failure
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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