TreeWAS – Variant ID: rs115048639

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.999	0.001	0.000
Chapter XI Diseases of the digestive system	0.999	0.001	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
C44 Other malignant neoplasms of skin	0.998	0.002	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.998	0.002	0.000
N20-N23 Urolithiasis	0.996	0.004	0.000
E00-E07 Disorders of thyroid gland	0.995	0.005	0.000
I25 Chronic ischaemic heart disease	0.994	0.006	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.994	0.006	0.000
E03 Other hypothyroidism	0.992	0.008	0.000
Chapter XXI Factors influencing health status and contact with health services	0.992	0.008	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008	0.000
K20 Oesophagitis	0.991	0.009	0.000
N20 Calculus of kidney and ureter	0.991	0.009	0.000
E03.9 Hypothyroidism, unspecified	0.990	0.010	0.000
C44.3 Skin of other and unspecified parts of face	0.990	0.010	0.000
E70-E90 Metabolic disorders	0.990	0.010	0.000
N17-N19 Renal failure	0.987	0.013	0.000
L82 Seborrhoeic keratosis	0.984	0.016	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.982	0.018	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.981	0.019	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.979	0.021	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.977	0.023	0.000
S60-S69 Injuries to the wrist and hand	0.974	0.026	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.970	0.030	0.000
N19 Unspecified renal failure	0.967	0.033	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.964	0.036	0.000
K26 Duodenal ulcer	0.963	0.037	0.000
S61 Open wound of wrist and hand	0.957	0.043	0.000
N20.1 Calculus of ureter	0.955	0.045	0.000
E20-E35 Disorders of other endocrine glands	0.955	0.045	0.000
E78.5 Hyperlipidaemia, unspecified	0.954	0.046	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.953	0.047	0.000
I20 Angina pectoris	0.953	0.047	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.951	0.049	0.000
J45.9 Asthma, unspecified	0.000	0.051	0.949
N20.0 Calculus of kidney	0.945	0.055	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.945	0.055	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.941	0.059	0.000
S61.0 Open wound of finger(s) without damage to nail	0.939	0.061	0.000
J45 Asthma	0.001	0.062	0.937
Z95.1 Presence of aortocoronary bypass graft	0.935	0.065	0.000
J40-J47 Chronic lower respiratory diseases	0.002	0.070	0.928
Z95.2 Presence of prosthetic heart valve	0.930	0.070	0.000
Z85 Personal history of malignant neoplasm	0.929	0.071	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.927	0.073	0.000
C44.4 Skin of scalp and neck	0.926	0.074	0.000
K50-K52 Noninfective enteritis and colitis	0.925	0.075	0.000
D10-D36 Benign neoplasms	0.922	0.078	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.920	0.080	0.000
Chapter XX External causes of morbidity and mortality	0.917	0.083	0.000
I24 Other acute ischaemic heart diseases	0.915	0.085	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.904	0.096	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.898	0.102	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.897	0.103	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.896	0.104	0.000
E78.0 Pure hypercholesterolaemia	0.893	0.107	0.000
Z93 Artificial opening status	0.892	0.108	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.109	0.891
K51 Ulcerative colitis	0.890	0.110	0.000
N89 Other noninflammatory disorders of vagina	0.888	0.112	0.000
M15-M19 Arthrosis	0.888	0.112	0.000
I25.1 Atherosclerotic heart disease	0.887	0.113	0.000
K22 Other diseases of oesophagus	0.882	0.118	0.000
J47 Bronchiectasis	0.001	0.118	0.881
C44.1 Skin of eyelid, including canthus	0.880	0.120	0.000
N80 Endometriosis	0.880	0.120	0.000
N23 Unspecified renal colic	0.880	0.120	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.880	0.120	0.000
N92 Excessive, frequent and irregular menstruation	0.880	0.120	0.000
M19 Other arthrosis	0.879	0.121	0.000
Chapter V Mental and behavioural disorders	0.876	0.124	0.000
K04 Diseases of pulp and periapical tissues	0.875	0.125	0.000
M05-M14 Inflammatory polyarthropathies	0.874	0.126	0.000
N18 Chronic renal failure	0.872	0.128	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.871	0.129	0.000
C43 Malignant melanoma of skin	0.869	0.131	0.000
I10-I15 Hypertensive diseases	0.869	0.131	0.000
L03 Cellulitis	0.863	0.137	0.000
I20.9 Angina pectoris, unspecified	0.862	0.138	0.000
D23 Other benign neoplasms of skin	0.861	0.139	0.000
M19.9 Arthrosis, unspecified	0.858	0.142	0.000
E86 Volume depletion	0.855	0.145	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.851	0.149	0.000
I20.0 Unstable angina	0.850	0.150	0.000
Chapter VI Diseases of the nervous system	0.848	0.152	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.847	0.153	0.000
Z92 Personal history of medical treatment	0.847	0.153	0.000
K51.9 Ulcerative colitis, unspecified	0.846	0.154	0.000
K07 Dentofacial anomalies [including malocclusion]	0.842	0.158	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.842	0.158	0.000
K22.1 Ulcer of oesophagus	0.839	0.161	0.000
T66-T78 Other and unspecified effects of external causes	0.836	0.164	0.000
C64-C68 Malignant neoplasms of urinary tract	0.836	0.164	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.834	0.166	0.000
L40-L45 Papulosquamous disorders	0.832	0.168	0.000
I30-I52 Other forms of heart disease	0.830	0.170	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.828	0.172	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.827	0.173	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.825	0.175	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.825	0.175	0.000
D00-D09 In situ neoplasms	0.823	0.177	0.000
K29 Gastritis and duodenitis	0.821	0.179	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.819	0.181	0.000
S61.8 Open wound of other parts of wrist and hand	0.814	0.186	0.000
S90-S99 Injuries to the ankle and foot	0.813	0.187	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.811	0.189	0.000
N00-N08 Glomerular diseases	0.810	0.189	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.809	0.191	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.806	0.194	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.806	0.194	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.194	0.806
I24.9 Acute ischaemic heart disease, unspecified	0.805	0.195	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.805	0.195	0.000
K14 Diseases of tongue	0.804	0.196	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.802	0.197	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.801	0.199	0.000
J40 Bronchitis, not specified as acute or chronic	0.001	0.201	0.798
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.798	0.202	0.000
E50-E64 Other nutritional deficiencies	0.797	0.203	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.203	0.796
Z93.2 Ileostomy status	0.796	0.204	0.000
W00-W19 Falls	0.795	0.205	0.000
N87 Dysplasia of cervix uteri	0.794	0.206	0.000
M45-M49 Spondylopathies	0.793	0.207	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.791	0.209	0.000
E21.3 Hyperparathyroidism, unspecified	0.789	0.211	0.000
N10-N16 Renal tubulo-interstitial diseases	0.789	0.211	0.000
C15-C26 Malignant neoplasms of digestive organs	0.789	0.211	0.000
I71 Aortic aneurysm and dissection	0.788	0.212	0.000
I25.5 Ischaemic cardiomyopathy	0.788	0.212	0.000
N20.2 Calculus of kidney with calculus of ureter	0.786	0.214	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.786	0.214	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.785	0.215	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.785	0.215	0.000
K05 Gingivitis and periodontal diseases	0.785	0.215	0.000
G56 Mononeuropathies of upper limb	0.783	0.217	0.000
M19.0 Primary arthrosis of other joints	0.782	0.218	0.000
S70-S79 Injuries to the hip and thigh	0.781	0.219	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.780	0.220	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.777	0.223	0.000
N18.9 Chronic renal failure, unspecified	0.775	0.225	0.000
K26.5 Chronic or unspecified with perforation	0.775	0.225	0.000
C44.7 Skin of lower limb, including hip	0.775	0.225	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.773	0.227	0.000
I24.8 Other forms of acute ischaemic heart disease	0.773	0.227	0.000
M70-M79 Other soft tissue disorders	0.773	0.227	0.000
Z89 Acquired absence of limb	0.772	0.228	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.772	0.228	0.000
M13 Other arthritis	0.770	0.230	0.000
K04.8 Radicular cyst	0.769	0.231	0.000
Z94 Transplanted organ and tissue status	0.769	0.231	0.000
E29 Testicular dysfunction	0.766	0.233	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.766	0.234	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.765	0.235	0.000
G56.0 Carpal tunnel syndrome	0.764	0.236	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.764	0.236	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.764	0.236	0.000
K29.8 Duodenitis	0.763	0.237	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.761	0.239	0.000
D27 Benign neoplasm of ovary	0.761	0.239	0.000
Z93.3 Colostomy status	0.757	0.243	0.000
I05-I09 Chronic rheumatic heart diseases	0.757	0.243	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.755	0.244	0.000
S20-S29 Injuries to the thorax	0.755	0.245	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.755	0.245	0.000
N80.1 Endometriosis of ovary	0.754	0.246	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.754	0.246	0.000
N92.3 Ovulation bleeding	0.753	0.247	0.000
I10 Essential (primary) hypertension	0.752	0.248	0.000
N99-N99 Other disorders of the genitourinary system	0.751	0.248	0.000
D23.1 Skin of eyelid, including canthus	0.751	0.249	0.000
L81 Other disorders of pigmentation	0.751	0.249	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.751	0.249	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.750	0.250	0.000
K22.2 Oesophageal obstruction	0.750	0.250	0.000
C67 Malignant neoplasm of bladder	0.749	0.251	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.748	0.252	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.746	0.254	0.000
E28 Ovarian dysfunction	0.746	0.254	0.000
D18 Haemangioma and lymphangioma, any site	0.746	0.254	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.743	0.257	0.000
M00-M03 Infectious arthropathies	0.742	0.258	0.000
L89 Decubitus ulcer	0.741	0.259	0.000
E23 Hypofunction and other disorders of pituitary gland	0.739	0.261	0.000
N80.3 Endometriosis of pelvic peritoneum	0.739	0.261	0.000
S62 Fracture at wrist and hand level	0.739	0.261	0.000
M65-M68 Disorders of synovium and tendon	0.738	0.262	0.000
L20-L30 Dermatitis and eczema	0.738	0.262	0.000
J43 Emphysema	0.001	0.263	0.736
E06 Thyroiditis	0.737	0.263	0.000
D22 Melanocytic naevi	0.735	0.265	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.735	0.265	0.000
Chapter VIII Diseases of the ear and mastoid process	0.735	0.265	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.733	0.267	0.000
N97 Female infertility	0.732	0.268	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.732	0.268	0.000
M91-M94 Chondropathies	0.732	0.268	0.000
E21.0 Primary hyperparathyroidism	0.732	0.268	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.731	0.269	0.000
C44.2 Skin of ear and external auricular canal	0.728	0.271	0.000
I35 Nonrheumatic aortic valve disorders	0.728	0.272	0.000
L50-L54 Urticaria and erythema	0.728	0.272	0.000
K12 Stomatitis and related lesions	0.727	0.273	0.000
S50-S59 Injuries to the elbow and forearm	0.727	0.273	0.000
K26.3 Acute without haemorrhage or perforation	0.726	0.274	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.726	0.274	0.000
Chapter VII Diseases of the eye and adnexa	0.725	0.275	0.000
K11 Diseases of salivary glands	0.725	0.275	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.725	0.275	0.000
T78 Adverse effects, not elsewhere classified	0.724	0.276	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.724	0.276	0.000
Z95.3 Presence of xenogenic heart valve	0.724	0.276	0.000
K07.3 Anomalies of tooth position	0.724	0.276	0.000
Y57 Other and unspecified drugs and medicaments	0.723	0.277	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.723	0.277	0.000
K26.4 Chronic or unspecified with haemorrhage	0.722	0.278	0.000
D45 Polycythaemia vera	0.722	0.278	0.000
L90 Atrophic disorders of skin	0.721	0.279	0.000
N25-N29 Other disorders of kidney and ureter	0.721	0.279	0.000
L03.2 Cellulitis of face	0.720	0.280	0.000
N86 Erosion and ectropion of cervix uteri	0.720	0.280	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.719	0.281	0.000
L03.3 Cellulitis of trunk	0.717	0.283	0.000
F41 Other anxiety disorders	0.717	0.283	0.000
Chapter XXII Codes for special purposes	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283	0.000
N95 Menopausal and other perimenopausal disorders	0.717	0.283	0.000
E40-E46 Malnutrition	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
L10-L14 Bullous disorders	0.716	0.284	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.716	0.284	0.000
C44.8 Overlapping lesion of skin	0.716	0.284	0.000
E88 Other metabolic disorders	0.716	0.284	0.000
K28 Gastrojejunal ulcer	0.715	0.284	0.000
K27 Peptic ulcer, site unspecified	0.715	0.284	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.715	0.284	0.000
D23.6 Skin of upper limb, including shoulder	0.715	0.285	0.000
C44.0 Skin of lip	0.715	0.285	0.000
W20-W49 Exposure to inanimate mechanical forces	0.714	0.286	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.714	0.286	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.714	0.286	0.000
E00 Congenital iodine-deficiency syndrome	0.714	0.286	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.714	0.286	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.713	0.287	0.000
I25.6 Silent myocardial ischaemia	0.713	0.287	0.000
I25.4 Coronary artery aneurysm	0.713	0.287	0.000
I25.3 Aneurysm of heart	0.713	0.287	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.713	0.287	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.713	0.287	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.713	0.287	0.000
L94 Other localised connective tissue disorders	0.713	0.287	0.000
L93 Lupus erythematosus	0.713	0.287	0.000
L87 Transepidermal elimination disorders	0.713	0.287	0.000
L88 Pyoderma gangrenosum	0.713	0.287	0.000
L86 Keratoderma in diseases classified elsewhere	0.713	0.287	0.000
L84 Corns and callosities	0.713	0.287	0.000
L83 Acanthosis nigricans	0.713	0.287	0.000
L80 Vitiligo	0.713	0.287	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.711	0.288	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.711	0.288	0.000
E03.8 Other specified hypothyroidism	0.711	0.288	0.000
E03.5 Myxoedema coma	0.711	0.288	0.000
E03.4 Atrophy of thyroid (acquired)	0.711	0.288	0.000
E03.3 Postinfectious hypothyroidism	0.711	0.288	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.711	0.288	0.000
E03.1 Congenital hypothyroidism without goitre	0.711	0.288	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.711	0.288	0.000
T79-T79 Certain early complications of trauma	0.711	0.289	0.000
T33-T35 Frostbite	0.711	0.289	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.711	0.289	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.711	0.289	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289	0.000
T00-T07 Injuries involving multiple body regions	0.711	0.289	0.000
S10-S19 Injuries to the neck	0.711	0.289	0.000
N20.9 Urinary calculus, unspecified	0.710	0.290	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.710	0.290	0.000
E85 Amyloidosis	0.710	0.290	0.000
E84 Cystic fibrosis	0.710	0.290	0.000
E79 Disorders of purine and pyrimidine metabolism	0.710	0.290	0.000
E77 Disorders of glycoprotein metabolism	0.710	0.290	0.000
E76 Disorders of glycosaminoglycan metabolism	0.710	0.290	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.710	0.290	0.000
E74 Other disorders of carbohydrate metabolism	0.710	0.290	0.000
E73 Lactose intolerance	0.710	0.290	0.000
E72 Other disorders of amino-acid metabolism	0.710	0.290	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.710	0.290	0.000
E70 Disorders of aromatic amino-acid metabolism	0.710	0.290	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.710	0.290	0.000
C44.6 Skin of upper limb, including shoulder	0.709	0.291	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.708	0.292	0.000
M11 Other crystal arthropathies	0.707	0.293	0.000
D23.7 Skin of lower limb, including hip	0.705	0.295	0.000
I77 Other disorders of arteries and arterioles	0.705	0.295	0.000
K30 Dyspepsia	0.705	0.295	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.705	0.295	0.000
N18.2 Chronic kidney disease, stage 2	0.704	0.296	0.000
Z84 Family history of other conditions	0.704	0.296	0.000
Z81 Family history of mental and behavioural disorders	0.704	0.296	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.704	0.296	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.703	0.297	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.703	0.297	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.297	0.703
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.703	0.297	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.702	0.298	0.000
E78.8 Other disorders of lipoprotein metabolism	0.702	0.298	0.000
E78.6 Lipoprotein deficiency	0.702	0.298	0.000
E78.4 Other hyperlipidaemia	0.702	0.298	0.000
E78.3 Hyperchylomicronaemia	0.702	0.298	0.000
E78.2 Mixed hyperlipidaemia	0.702	0.298	0.000
E78.1 Pure hyperglyceridaemia	0.702	0.298	0.000
J45.0 Predominantly allergic asthma	0.001	0.299	0.701
N98 Complications associated with artificial fertilisation	0.701	0.299	0.000
N91 Absent, scanty and rare menstruation	0.701	0.299	0.000
N82 Fistulae involving female genital tract	0.701	0.299	0.000
N96 Habitual aborter	0.701	0.299	0.000
K51.2 Ulcerative (chronic) proctitis	0.700	0.300	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.700	0.300	0.000
I22 Subsequent myocardial infarction	0.700	0.300	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.698	0.302	0.000
S69 Other and unspecified injuries of wrist and hand	0.698	0.302	0.000
S67 Crushing injury of wrist and hand	0.698	0.302	0.000
S65 Injury of blood vessels at wrist and hand level	0.698	0.302	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.698	0.302	0.000
S60 Superficial injury of wrist and hand	0.698	0.302	0.000
I60-I69 Cerebrovascular diseases	0.698	0.302	0.000
K51.8 Other ulcerative colitis	0.696	0.304	0.000
K10 Other diseases of jaws	0.696	0.304	0.000
K09 Cysts of oral region, not elsewhere classified	0.696	0.304	0.000
K03 Other diseases of hard tissues of teeth	0.696	0.304	0.000
K00 Disorders of tooth development and eruption	0.696	0.304	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.695	0.304	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.695	0.305	0.000
I20.8 Other forms of angina pectoris	0.694	0.305	0.000
N84 Polyp of female genital tract	0.694	0.306	0.000
N80.0 Endometriosis of uterus	0.693	0.307	0.000
E07 Other disorders of thyroid	0.693	0.307	0.000
L40 Psoriasis	0.692	0.308	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.692	0.308	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.691	0.309	0.000
M60-M63 Disorders of muscles	0.691	0.309	0.000
E05.9 Thyrotoxicosis, unspecified	0.691	0.309	0.000
N21 Calculus of lower urinary tract	0.691	0.309	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.690	0.310	0.000
K26.2 Acute with both haemorrhage and perforation	0.690	0.310	0.000
K26.1 Acute with perforation	0.690	0.310	0.000
K26.0 Acute with haemorrhage	0.690	0.310	0.000
Z60 Problems related to social environment	0.690	0.310	0.000
D32 Benign neoplasm of meninges	0.690	0.310	0.000
K90-K93 Other diseases of the digestive system	0.690	0.310	0.000
D48.1 Connective and other soft tissue	0.689	0.311	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.688	0.312	0.000
Z31 Procreative management	0.688	0.312	0.000
S68 Traumatic amputation of wrist and hand	0.688	0.312	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.687	0.313	0.000
F41.2 Mixed anxiety and depressive disorder	0.687	0.313	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.687	0.313	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.686	0.313	0.000
S61.7 Multiple open wounds of wrist and hand	0.686	0.314	0.000
D03 Melanoma in situ	0.685	0.315	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.685	0.315	0.000
E34 Other endocrine disorders	0.685	0.315	0.000
E32 Diseases of thymus	0.685	0.315	0.000
E31 Polyglandular dysfunction	0.685	0.315	0.000
E30 Disorders of puberty, not elsewhere classified	0.685	0.315	0.000
E27 Other disorders of adrenal gland	0.685	0.315	0.000
E26 Hyperaldosteronism	0.685	0.315	0.000
E25 Adrenogenital disorders	0.685	0.315	0.000
E24 Cushing's syndrome	0.685	0.315	0.000
E22 Hyperfunction of pituitary gland	0.685	0.315	0.000
E20 Hypoparathyroidism	0.685	0.315	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.685	0.315	0.000
K25 Gastric ulcer	0.684	0.316	0.000
M75 Shoulder lesions	0.684	0.316	0.000
M80-M85 Disorders of bone density and structure	0.683	0.317	0.000
I20.1 Angina pectoris with documented spasm	0.683	0.317	0.000
L03.0 Cellulitis of finger and toe	0.683	0.317	0.000
I72 Other aneurysm	0.683	0.317	0.000
K14.8 Other diseases of tongue	0.682	0.318	0.000
D46 Myelodysplastic syndromes	0.682	0.318	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.682	0.318	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.682	0.318	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.682	0.318	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.682	0.318	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.682	0.318	0.000
L08 Other local infections of skin and subcutaneous tissue	0.681	0.319	0.000
X60-X84 Intentional self-harm	0.681	0.319	0.000
I44 Atrioventricular and left bundle-branch block	0.681	0.319	0.000
Z02 Examination and encounter for administrative purposes	0.681	0.319	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.680	0.319	0.000
M86-M90 Other osteopathies	0.679	0.320	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.678	0.322	0.000
I42 Cardiomyopathy	0.677	0.323	0.000
S40-S49 Injuries to the shoulder and upper arm	0.677	0.323	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.677	0.323	0.000
M40-M43 Deforming dorsopathies	0.676	0.323	0.000
E83 Disorders of mineral metabolism	0.676	0.324	0.000
Z04 Examination and observation for other reasons	0.675	0.325	0.000
S64 Injury of nerves at wrist and hand level	0.674	0.325	0.000
I36 Nonrheumatic tricuspid valve disorders	0.674	0.326	0.000
D23.4 Skin of scalp and neck	0.674	0.326	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.674	0.326	0.000
J45.8 Mixed asthma	0.001	0.327	0.672
J45.1 Nonallergic asthma	0.001	0.327	0.672
I12 Hypertensive renal disease	0.672	0.328	0.000
K02 Dental caries	0.671	0.329	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.671	0.329	0.000
I74 Arterial embolism and thrombosis	0.671	0.329	0.000
I95 Hypotension	0.671	0.329	0.000
M10 Gout	0.670	0.330	0.000
N03 Chronic nephritic syndrome	0.670	0.330	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.669	0.331	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.669	0.331	0.000
M13.9 Arthritis, unspecified	0.669	0.331	0.000
S90 Superficial injury of ankle and foot	0.669	0.331	0.000
Chapter X Diseases of the respiratory system	0.635	0.332	0.033
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.668	0.332	0.000
J41 Simple and mucopurulent chronic bronchitis	0.002	0.333	0.665
N17 Acute renal failure	0.667	0.333	0.000
Z85.0 Personal history of malignant neoplasm of digestive organs	0.666	0.334	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.666	0.334	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.666	0.334	0.000
M19.1 Posttraumatic arthrosis of other joints	0.666	0.334	0.000
L03.8 Cellulitis of other sites	0.666	0.334	0.000
I78 Diseases of capillaries	0.666	0.334	0.000
Z92.8 Personal history of other medical treatment	0.665	0.335	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.665	0.335	0.000
K13 Other diseases of lip and oral mucosa	0.665	0.335	0.000
Z97 Presence of other devices	0.664	0.335	0.000
L04 Acute lymphadenitis	0.664	0.336	0.000
L01 Impetigo	0.664	0.336	0.000
L00 Staphylococcal scalded skin syndrome	0.664	0.336	0.000
N18.4 Chronic kidney disease, stage 4	0.664	0.336	0.000
L05 Pilonidal cyst	0.664	0.336	0.000
C67.9 Bladder, unspecified	0.664	0.336	0.000
I33 Acute and subacute endocarditis	0.663	0.336	0.000
L98.0 Pyogenic granuloma	0.663	0.337	0.000
N71 Inflammatory disease of uterus, except cervix	0.663	0.337	0.000
H53-H54 Visual disturbances and blindness	0.662	0.338	0.000
D31 Benign neoplasm of eye and adnexa	0.661	0.339	0.000
D30 Benign neoplasm of urinary organs	0.661	0.339	0.000
D29 Benign neoplasm of male genital organs	0.661	0.339	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.661	0.339	0.000
D26 Other benign neoplasms of uterus	0.661	0.339	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.661	0.339	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.661	0.339	0.000
D19 Benign neoplasm of mesothelial tissue	0.661	0.339	0.000
D16 Benign neoplasm of bone and articular cartilage	0.661	0.339	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.661	0.339	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.661	0.339	0.000
D10 Benign neoplasm of mouth and pharynx	0.661	0.339	0.000
D34 Benign neoplasm of thyroid gland	0.661	0.339	0.000
W10 Fall on and from stairs and steps	0.661	0.339	0.000
I70 Atherosclerosis	0.660	0.340	0.000
K26.7 Chronic without haemorrhage or perforation	0.660	0.340	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.660	0.340	0.000
Z93.1 Gastrostomy status	0.660	0.340	0.000
C20 Malignant neoplasm of rectum	0.660	0.340	0.000
N87.1 Moderate cervical dysplasia	0.659	0.341	0.000
M05 Seropositive rheumatoid arthritis	0.659	0.341	0.000
S00-S09 Injuries to the head	0.659	0.341	0.000
F80-F89 Disorders of psychological development	0.658	0.341	0.000
F30-F39 Mood [affective] disorders	0.659	0.341	0.000
K07.6 Temporomandibular joint disorders	0.658	0.342	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.658	0.342	0.000
Y35-Y36 Legal intervention and operations of war	0.658	0.342	0.000
Y10-Y34 Event of undetermined intent	0.658	0.342	0.000
Y00-Y09 Assault	0.658	0.342	0.000
X85-X99 Assault	0.658	0.342	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.658	0.342	0.000
X50-X57 Overexertion, travel and privation	0.658	0.342	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.658	0.342	0.000
X30-X39 Exposure to forces of nature	0.658	0.342	0.000
X20-X29 Contact with venomous animals and plants	0.658	0.342	0.000
X10-X19 Contact with heat and hot substances	0.658	0.342	0.000
X00-X09 Exposure to smoke, fire and flames	0.658	0.342	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.658	0.342	0.000
W75-W84 Other accidental threats to breathing	0.658	0.342	0.000
W65-W74 Accidental drowning and submersion	0.658	0.342	0.000
W50-W64 Exposure to animate mechanical forces	0.658	0.342	0.000
V98-V99 Other and unspecified transport accidents	0.658	0.342	0.000
V95-V97 Air and space transport accidents	0.658	0.342	0.000
V90-V94 Water transport accidents	0.658	0.342	0.000
V80-V89 Other land transport accidents	0.658	0.342	0.000
V70-V79 Bus occupant injured in transport accident	0.658	0.342	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.658	0.342	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.658	0.342	0.000
V40-V49 Car occupant injured in transport accident	0.658	0.342	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations