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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115081579
log Bayes Factor = 14.3442
Chromosome 3   position 178,513,059  (GRCh37) Explore rs115081579 on Ensembl!
Variant rs115081579 is part of Cluster X0154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
C50-C50 Malignant neoplasm of breast
0.999 0.001 0.000
C50 Malignant neoplasm of breast
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
S00-S09 Injuries to the head
0.997 0.003 0.000
O60-O75 Complications of labour and delivery
0.996 0.004 0.000
C50.9 Breast, unspecified
0.996 0.004 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.996 0.004 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.980 0.020 0.000
S00 Superficial injury of head
0.979 0.021 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
O70 Perineal laceration during delivery
0.960 0.040 0.000
Y43 Primarily systemic agents
0.959 0.041 0.000
S00.8 Superficial injury of other parts of head
0.955 0.045 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.954 0.046 0.000
S01 Open wound of head
0.946 0.054 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.945 0.055 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.945 0.055 0.000
C50.4 Upper-outer quadrant of breast
0.942 0.058 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.941 0.059 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.939 0.061 0.000
Chapter VII Diseases of the eye and adnexa
0.937 0.063 0.000
Z37 Outcome of delivery
0.937 0.063 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.934 0.066 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.927 0.073 0.000
O70.1 Second degree perineal laceration during delivery
0.927 0.073 0.000
Z13 Special screening examination for other diseases and disorders
0.926 0.074 0.000
Y43.3 Other antineoplastic drugs
0.922 0.078 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.921 0.079 0.000
G62 Other polyneuropathies
0.920 0.080 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.920 0.080 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.918 0.082 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.913 0.087 0.000
Z51 Other medical care
0.909 0.091 0.000
Z37.0 Single live birth
0.908 0.092 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.906 0.094 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.904 0.096 0.000
Z13.9 Special screening examination, unspecified
0.903 0.097 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.896 0.104 0.000
G40-G47 Episodic and paroxysmal disorders
0.896 0.104 0.000
Z51.1 Chemotherapy session for neoplasm
0.893 0.107 0.000
G62.9 Polyneuropathy, unspecified
0.888 0.112 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.880 0.120 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.873 0.127 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.871 0.129 0.000
H04 Disorders of lachrymal system
0.868 0.132 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.867 0.133 0.000
C50.5 Lower-outer quadrant of breast
0.866 0.134 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.865 0.135 0.000
S06 Intracranial injury
0.859 0.141 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.857 0.143 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.855 0.144 0.000
C50.3 Lower-inner quadrant of breast
0.855 0.145 0.000
Z12 Special screening examination for neoplasms
0.852 0.148 0.000
S40-S49 Injuries to the shoulder and upper arm
0.852 0.148 0.000
Chapter V Mental and behavioural disorders
0.851 0.149 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.850 0.150 0.000
Y45.1 Salicylates
0.848 0.152 0.000
Chapter XXII Codes for special purposes
0.848 0.152 0.000
O47 False labour
0.840 0.160 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.837 0.163 0.000
O66 Other obstructed labour
0.836 0.164 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.835 0.165 0.000
C79 Secondary malignant neoplasm of other sites
0.834 0.166 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.829 0.171 0.000
V10-V19 Pedal cyclist injured in transport accident
0.826 0.174 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.826 0.174 0.000
H04.2 Epiphora
0.825 0.175 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.822 0.178 0.000
O16 Unspecified maternal hypertension
0.821 0.179 0.000
Z30 Contraceptive management
0.820 0.180 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.820 0.180 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.818 0.182 0.000
Z34 Supervision of normal pregnancy
0.818 0.182 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.818 0.182 0.000
S01.0 Open wound of scalp
0.816 0.184 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.812 0.188 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.812 0.188 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.810 0.190 0.000
S20-S29 Injuries to the thorax
0.808 0.192 0.000
Z33 Pregnant state, incidental
0.804 0.196 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.801 0.199 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.798 0.202 0.000
X50-X57 Overexertion, travel and privation
0.798 0.202 0.000
F30-F39 Mood [affective] disorders
0.797 0.203 0.000
M06 Other rheumatoid arthritis
0.796 0.204 0.000
Y57 Other and unspecified drugs and medicaments
0.795 0.205 0.000
M06.9 Rheumatoid arthritis, unspecified
0.794 0.206 0.000
T91 Sequelae of injuries of neck and trunk
0.793 0.207 0.000
S01.2 Open wound of nose
0.793 0.207 0.000
T92 Sequelae of injuries of upper limb
0.792 0.208 0.000
S80-S89 Injuries to the knee and lower leg
0.792 0.208 0.000
O75.8 Other specified complications of labour and delivery
0.792 0.208 0.000
M05-M14 Inflammatory polyarthropathies
0.791 0.209 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.790 0.210 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.788 0.212 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.788 0.212 0.000
T66-T78 Other and unspecified effects of external causes
0.788 0.212 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.787 0.213 0.000
O75.0 Maternal distress during labour and delivery
0.784 0.216 0.000
Chapter X Diseases of the respiratory system
0.784 0.216 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.784 0.216 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.782 0.218 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.778 0.222 0.000
G62.8 Other specified polyneuropathies
0.777 0.223 0.000
G70-G73 Diseases of myoneural junction and muscle
0.776 0.224 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.776 0.224 0.000
Y42.5 Other oestrogens and progestogens
0.775 0.225 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.775 0.225 0.000
C51-C58 Malignant neoplasms of female genital organs
0.775 0.225 0.000
S00.0 Superficial injury of scalp
0.773 0.227 0.000
G47 Sleep disorders
0.772 0.228 0.000
Chapter I Certain infectious and parasitic diseases
0.771 0.229 0.000
S01.5 Open wound of lip and oral cavity
0.771 0.229 0.000
Y40 Systemic antibiotics
0.770 0.230 0.000
W20-W49 Exposure to inanimate mechanical forces
0.769 0.231 0.000
O42 Premature rupture of membranes
0.769 0.231 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.769 0.231 0.000
Y52 Agents primarily affecting the cardiovascular system
0.769 0.231 0.000
Y43.1 Antineoplastic antimetabolites
0.767 0.233 0.000
T79-T79 Certain early complications of trauma
0.766 0.234 0.000
S00.1 Contusion of eyelid and periocular area
0.766 0.234 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.766 0.234 0.000
G40 Epilepsy
0.765 0.235 0.000
C77.9 Lymph node, unspecified
0.762 0.238 0.000
S70-S79 Injuries to the hip and thigh
0.759 0.241 0.000
Z43 Attention to artificial openings
0.759 0.241 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.757 0.243 0.000
Chapter IX Diseases of the circulatory system
0.757 0.243 0.000
O48 Prolonged pregnancy
0.755 0.245 0.000
O00-O08 Pregnancy with abortive outcome
0.753 0.246 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.752 0.248 0.000
F32 Depressive episode
0.750 0.250 0.000
G43 Migraine
0.749 0.251 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.749 0.251 0.000
O72 Postpartum haemorrhage
0.748 0.251 0.000
Z02 Examination and encounter for administrative purposes
0.748 0.252 0.000
O70.0 First degree perineal laceration during delivery
0.746 0.254 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.745 0.255 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.745 0.255 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.744 0.256 0.000
Z51.3 Blood transfusion without reported diagnosis
0.741 0.259 0.000
V20-V29 Motorcycle rider injured in transport accident
0.739 0.261 0.000
S01.8 Open wound of other parts of head
0.736 0.264 0.000
T93 Sequelae of injuries of lower limb
0.735 0.265 0.000
Z13.1 Special screening examination for diabetes mellitus
0.735 0.265 0.000
S60-S69 Injuries to the wrist and hand
0.733 0.266 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.733 0.267 0.000
S01.1 Open wound of eyelid and periocular area
0.732 0.268 0.000
G90-G99 Other disorders of the nervous system
0.732 0.268 0.000
I30-I52 Other forms of heart disease
0.731 0.269 0.000
T98 Sequelae of other and unspecified effects of external causes
0.729 0.271 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.729 0.271 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.728 0.272 0.000
S02 Fracture of skull and facial bones
0.728 0.272 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.728 0.272 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.728 0.272 0.000
O47.0 False labour before 37 completed weeks of gestation
0.727 0.272 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.727 0.273 0.000
H02 Other disorders of eyelid
0.726 0.274 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.726 0.274 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.725 0.275 0.000
S00.9 Superficial injury of head, part unspecified
0.725 0.275 0.000
Z44 Fitting and adjustment of external prosthetic device
0.725 0.275 0.000
O40 Polyhydramnios
0.723 0.277 0.000
C50.8 Overlapping lesion of breast
0.723 0.277 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.722 0.278 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.722 0.278 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.721 0.279 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.721 0.279 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.720 0.279 0.000
M06.0 Seronegative rheumatoid arthritis
0.719 0.281 0.000
D80-D89 Certain disorders involving the immune mechanism
0.719 0.281 0.000
O36 Maternal care for other known or suspected foetal problems
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.716 0.284 0.000
C50.6 Axillary tail of breast
0.716 0.284 0.000
C50.0 Nipple and areola
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.715 0.285 0.000
F32.9 Depressive episode, unspecified
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.715 0.285 0.000
S07 Crushing injury of head
0.715 0.285 0.000
S05 Injury of eye and orbit
0.715 0.285 0.000
S04 Injury of cranial nerves
0.715 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.715 0.285 0.000
S40 Superficial injury of shoulder and upper arm
0.714 0.286 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.286 0.000
O71 Other obstetric trauma
0.714 0.286 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.714 0.286 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.714 0.286 0.000
O61 Failed induction of labour
0.714 0.286 0.000
O60 Preterm delivery
0.714 0.286 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.714 0.286 0.000
Z10 Routine general health check-up of defined subpopulation
0.714 0.286 0.000
Y59 Other and unspecified vaccines and biological substances
0.714 0.286 0.000
Y58 Bacterial vaccines
0.714 0.286 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.714 0.286 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.714 0.286 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.714 0.286 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.714 0.286 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
Y48 Anaesthetics and therapeutic gases
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.714 0.286 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.714 0.286 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.713 0.286 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.713 0.287 0.000
Z39 Postpartum care and examination
0.712 0.288 0.000
H10-H13 Disorders of conjunctiva
0.711 0.289 0.000
H55-H59 Other disorders of eye and adnexa
0.708 0.292 0.000
O73 Retained placenta and membranes, without haemorrhage
0.706 0.294 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.705 0.295 0.000
H04.1 Other disorders of lachrymal gland
0.704 0.296 0.000
O62 Abnormalities of forces of labour
0.704 0.296 0.000
M80-M85 Disorders of bone density and structure
0.704 0.296 0.000
Z51.5 Palliative care
0.703 0.297 0.000
G41 Status epilepticus
0.703 0.297 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.703 0.297 0.000
Z09.4 Follow-up examination after treatment of fracture
0.703 0.297 0.000
Z09.3 Follow-up examination after psychotherapy
0.703 0.297 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.703 0.297 0.000
S00.7 Multiple superficial injuries of head
0.702 0.298 0.000
S00.5 Superficial injury of lip and oral cavity
0.702 0.298 0.000
S00.4 Superficial injury of ear
0.702 0.298 0.000
S00.3 Superficial injury of nose
0.702 0.298 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.702 0.298 0.000
Z54 Convalescence
0.702 0.298 0.000
Z38 Liveborn infants according to place of birth
0.701 0.299 0.000
Z32 Pregnancy examination and test
0.701 0.299 0.000
Z31 Procreative management
0.701 0.299 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.699 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.300 0.000
G82 Paraplegia and tetraplegia
0.699 0.301 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.699 0.301 0.000
C50.2 Upper-inner quadrant of breast
0.698 0.301 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.697 0.303 0.000
H02.4 Ptosis of eyelid
0.691 0.309 0.000
Z42 Follow-up care involving plastic surgery
0.691 0.309 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.690 0.310 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.690 0.310 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.690 0.310 0.000
J00-J06 Acute upper respiratory infections
0.690 0.310 0.000
H43-H45 Disorders of vitreous body and globe
0.689 0.311 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.689 0.311 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.688 0.312 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.688 0.312 0.000
O70.9 Perineal laceration during delivery, unspecified
0.688 0.312 0.000
O70.3 Fourth degree perineal laceration during delivery
0.688 0.312 0.000
O70.2 Third degree perineal laceration during delivery
0.688 0.312 0.000
Y43.9 Primarily systemic agent, unspecified
0.688 0.312 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.688 0.312 0.000
Y43.6 Enzymes, not elsewhere classified
0.688 0.312 0.000
Y43.5 Acidifying and alkalising agents
0.688 0.312 0.000
Y43.4 Immunosuppressive agents
0.688 0.312 0.000
Y43.2 Antineoplastic natural products
0.688 0.312 0.000
Y43.0 Antiallergic and antiemetic drugs
0.688 0.312 0.000
B95-B98 Bacterial, viral and other infectious agents
0.687 0.313 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.686 0.314 0.000
G47.9 Sleep disorder, unspecified
0.686 0.314 0.000
H01 Other inflammation of eyelid
0.686 0.314 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.685 0.315 0.000
C83.0 Small cell (diffuse)
0.685 0.315 0.000
S01.3 Open wound of ear
0.684 0.316 0.000
S06.2 Diffuse brain injury
0.684 0.316 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.684 0.316 0.000
O97 Death from sequelae of direct obstetric causes
0.684 0.316 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.684 0.316 0.000
O95 Obstetric death of unspecified cause
0.684 0.316 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.684 0.316 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
Z04 Examination and observation for other reasons
0.682 0.318 0.000
J60-J70 Lung diseases due to external agents
0.682 0.318 0.000
S01.7 Multiple open wounds of head
0.678 0.321 0.000
S01.4 Open wound of cheek and temporomandibular area
0.678 0.321 0.000
O75.9 Complication of labour and delivery, unspecified
0.678 0.322 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.678 0.322 0.000
O75.4 Other complications of obstetric surgery and procedures
0.678 0.322 0.000
O75.3 Other infection during labour
0.678 0.322 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.678 0.322 0.000
O75.1 Shock during or following labour and delivery
0.678 0.322 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.678 0.322 0.000
T21 Burn and corrosion of trunk
0.678 0.322 0.000
Chapter VIII Diseases of the ear and mastoid process
0.678 0.322 0.000
G61 Inflammatory polyneuropathy
0.677 0.323 0.000
G60 Hereditary and idiopathic neuropathy
0.677 0.323 0.000
G64 Other disorders of peripheral nervous system
0.677 0.323 0.000
S06.5 Traumatic subdural haemorrhage
0.677 0.323 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.676 0.324 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.676 0.324 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.675 0.324 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.675 0.325 0.000
C77.3 Axillary and upper limb lymph nodes
0.675 0.325 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.674 0.325 0.000
Y45.8 Other analgesics and antipyretics
0.674 0.325 0.000
Y45.5 4-Aminophenol derivatives
0.674 0.325 0.000
Y45.4 Antirheumatics
0.674 0.325 0.000
Y45.2 Propionic acid derivatives
0.674 0.325 0.000
X60-X84 Intentional self-harm
0.674 0.326 0.000
D10-D36 Benign neoplasms
0.674 0.326 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.674 0.326 0.000
O45 Premature separation of placenta [abruptio placentae]
0.673 0.327 0.000
O44 Placenta praevia
0.673 0.327 0.000
O43 Placental disorders
0.673 0.327 0.000
O41 Other disorders of amniotic fluid and membranes
0.673 0.327 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.673 0.327 0.000
O33 Maternal care for known or suspected disproportion
0.673 0.327 0.000
O31 Complications specific to multiple gestation
0.673 0.327 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.672 0.328 0.000
Z37.9 Outcome of delivery unspecified
0.672 0.328 0.000
Z37.7 Other multiple births, all stillborn
0.672 0.328 0.000
Z37.6 Other multiple births, some liveborn
0.672 0.328 0.000
Z37.5 Other multiple births, all liveborn
0.672 0.328 0.000
Z37.4 Twins, both stillborn
0.672 0.328 0.000
Z37.3 Twins, one liveborn and one stillborn
0.672 0.328 0.000
Z37.1 Single stillbirth
0.672 0.328 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.671 0.328 0.000
G30-G32 Other degenerative diseases of the nervous system
0.671 0.329 0.000
Y45.0 Opioids and related analgesics
0.671 0.329 0.000
O30 Multiple gestation
0.670 0.329 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
Z37.2 Twins, both liveborn
0.670 0.330 0.000
T95 Sequelae of burns, corrosions and frostbite
0.669 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.669 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.669 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.669 0.330 0.000
Z85 Personal history of malignant neoplasm
0.669 0.331 0.000
C79.6 Secondary malignant neoplasm of ovary
0.669 0.331 0.000
S90-S99 Injuries to the ankle and foot
0.669 0.331 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.669 0.331 0.000
S80 Superficial injury of lower leg
0.668 0.332 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.668 0.332 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.668 0.332 0.000
D37.4 Colon
0.668 0.332 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.664 0.336 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.664 0.336 0.000
Z13.5 Special screening examination for eye and ear disorders
0.664 0.336 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.664 0.336 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.664 0.336 0.000
Z13.2 Special screening examination for nutritional disorders
0.664 0.336 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.664 0.336 0.000
Z00.5 Examination of potential donor of organ and tissue
0.663 0.337 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.662 0.338 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.661 0.339 0.000
Z53.9 Procedure not carried out, unspecified reason
0.661 0.339 0.000
C01 Malignant neoplasm of base of tongue
0.661 0.339 0.000
G44 Other headache syndromes
0.660 0.340 0.000
Z43.3 Attention to colostomy
0.660 0.340 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
C77.0 Lymph nodes of head, face and neck
0.660 0.340 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.660 0.340 0.000
G62.2 Polyneuropathy due to other toxic agents
0.660 0.340 0.000
G62.1 Alcoholic polyneuropathy
0.660 0.340 0.000
G62.0 Drug-induced polyneuropathy
0.660 0.340 0.000
O15 Eclampsia
0.658 0.341 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.658 0.341 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.658 0.341 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.658 0.341 0.000
Z01.8 Other specified special examinations
0.657 0.343 0.000
Z53.0 Procedure not carried out because of contraindication
0.657 0.343 0.000
F99-F99 Unspecified mental disorder
0.656 0.344 0.000
D45 Polycythaemia vera
0.656 0.344 0.000
Y95 Nosocomial condition
0.655 0.345 0.000
D46 Myelodysplastic syndromes
0.655 0.345 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.655 0.345 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.655 0.345 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.655 0.345 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.655 0.345 0.000
X51 Travel and motion
0.654 0.346 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.653 0.347 0.000
Z52 Donors of organs and tissues
0.653 0.347 0.000
Z51.9 Medical care, unspecified
0.651 0.348 0.000
Z51.6 Desensitisation to allergens
0.651 0.348 0.000
Y57.9 Drug or medicament, unspecified
0.651 0.349 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.649 0.351 0.000
C95 Leukaemia of unspecified cell type
0.649 0.351 0.000
C94 Other leukaemias of specified cell type
0.649 0.351 0.000
C93 Monocytic leukaemia
0.649 0.351 0.000
C88 Malignant immunoproliferative diseases
0.649 0.351 0.000
C86 Other specified types of T/NK-cell lymphoma
0.649 0.351 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.649 0.351 0.000
C81 Hodgkin's disease
0.649 0.351 0.000
S42 Fracture of shoulder and upper arm
0.649 0.351 0.000
D18 Haemangioma and lymphangioma, any site
0.648 0.352 0.000
H05 Disorders of orbit
0.648 0.352 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.648 0.352 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.648 0.352 0.000
L40-L45 Papulosquamous disorders
0.647 0.353 0.000
T91.3 Sequelae of injury of spinal cord
0.647 0.353 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.647 0.353 0.000
M06.4 Inflammatory polyarthropathy
0.647 0.353 0.000
T90 Sequelae of injuries of head
0.646 0.353 0.000
H53-H54 Visual disturbances and blindness
0.646 0.354 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.646 0.354 0.000
C02.9 Tongue, unspecified
0.644 0.355 0.000
I05-I09 Chronic rheumatic heart diseases
0.644 0.356 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.644 0.356 0.000
C91 Lymphoid leukaemia
0.644 0.356 0.000
Y86 Sequelae of other accidents
0.643 0.357 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.643 0.357 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.642 0.357 0.000
U88 Agent resistant to multiple antibiotics
0.643 0.357 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.642 0.357 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.642 0.358 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.641 0.359 0.000
F60-F69 Disorders of adult personality and behaviour
0.640 0.360 0.000
O23 Infections of genito-urinary tract in pregnancy
0.640 0.360 0.000
S20 Superficial injury of thorax
0.640 0.360 0.000
H52 Disorders of refraction and accommodation
0.639 0.360 0.000
Z34.8 Supervision of other normal pregnancy
0.639 0.361 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.639 0.361 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.638 0.362 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.637 0.363 0.000
D17 Benign lipomatous neoplasm
0.637 0.363 0.000
O32.0 Maternal care for unstable lie
0.636 0.364 0.000
T78 Adverse effects, not elsewhere classified
0.636 0.364 0.000
M05 Seropositive rheumatoid arthritis
0.635 0.365 0.000
O47.9 False labour, unspecified
0.635 0.365 0.000
Z34.0 Supervision of normal first pregnancy
0.634 0.366 0.000
W44 Foreign body entering into or through eye or natural orifice
0.633 0.366 0.000
Z96 Presence of other functional implants
0.633 0.367 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.633 0.367 0.000
G70 Myasthenia gravis and other myoneural disorders
0.633 0.367 0.000
Z49 Care involving dialysis
0.633 0.367 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.632 0.368 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.631 0.369 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.631 0.369 0.000
D18.0 Haemangioma, any site
0.630 0.370 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.629 0.371 0.000
S09 Other and unspecified injuries of head
0.629 0.371 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.627 0.373 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.627 0.373 0.000
D50-D53 Nutritional anaemias
0.627 0.373 0.000
M81 Osteoporosis without pathological fracture
0.627 0.373 0.000
G43.9 Migraine, unspecified
0.627 0.373 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.626 0.373 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.626 0.374 0.000
C85.1 B-cell lymphoma, unspecified
0.626 0.374 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.626 0.374 0.000
Y85 Sequelae of transport accidents
0.626 0.374 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.626 0.374 0.000
S81 Open wound of lower leg
0.625 0.375 0.000
D00-D09 In situ neoplasms
0.624 0.376 0.000
H49 Paralytic strabismus
0.623 0.377 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.623 0.377 0.000
Z92 Personal history of medical treatment
0.623 0.377 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.623 0.377 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.622 0.378 0.000
H04.9 Disorder of lachrymal system, unspecified
0.622 0.378 0.000
H04.8 Other disorders of lachrymal system
0.622 0.378 0.000
H04.6 Other changes in lachrymal passages
0.622 0.378 0.000
H04.4 Chronic inflammation of lachrymal passages
0.622 0.378 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.622 0.378 0.000
H04.0 Dacryoadenitis
0.622 0.378 0.000
Y42.9 Other and unspecified hormone antagonists
0.621 0.379 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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