TreeWAS – Variant ID: rs115127256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.998	0.002
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.996	0.004
Chapter X Diseases of the respiratory system	0.994	0.006
R93 Abnormal findings on diagnostic imaging of other body structures	0.992	0.008
Chapter XIV Diseases of the genitourinary system	0.988	0.012
Chapter II Neoplasms	0.978	0.022
J09-J18 Influenza and pneumonia	0.976	0.024
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.974	0.026
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.973	0.027
R30-R39 Symptoms and signs involving the urinary system	0.972	0.028
Chapter XV Pregnancy, childbirth and the puerperium	0.966	0.034
R33 Retention of urine	0.964	0.036
J18 Pneumonia, organism unspecified	0.963	0.037
R04 Haemorrhage from respiratory passages	0.961	0.039
Chapter I Certain infectious and parasitic diseases	0.952	0.048
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.941	0.059
B95-B98 Bacterial, viral and other infectious agents	0.939	0.061
R91 Abnormal findings on diagnostic imaging of lung	0.937	0.063
J18.1 Lobar pneumonia, unspecified	0.935	0.065
Chapter VIII Diseases of the ear and mastoid process	0.930	0.070
M20-M25 Other joint disorders	0.930	0.070
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.930	0.070
C50-C50 Malignant neoplasm of breast	0.921	0.079
R04.0 Epistaxis	0.918	0.082
S60-S69 Injuries to the wrist and hand	0.918	0.082
N30-N39 Other diseases of urinary system	0.917	0.083
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.916	0.084
M80-M85 Disorders of bone density and structure	0.907	0.093
M20 Acquired deformities of fingers and toes	0.903	0.097
R00 Abnormalities of heart beat	0.902	0.098
Chapter IV Endocrine, nutritional and metabolic diseases	0.901	0.099
Chapter IX Diseases of the circulatory system	0.899	0.101
S00-S09 Injuries to the head	0.897	0.103
N17-N19 Renal failure	0.895	0.105
T36-T50 Poisoning by drugs, medicaments and biological substances	0.889	0.111
H90-H95 Other disorders of ear	0.888	0.112
Chapter XI Diseases of the digestive system	0.887	0.113
C50 Malignant neoplasm of breast	0.880	0.120
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.878	0.122
M45-M49 Spondylopathies	0.873	0.127
K55-K64 Other diseases of intestines	0.872	0.128
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.871	0.129
R26 Abnormalities of gait and mobility	0.870	0.130
O60-O75 Complications of labour and delivery	0.867	0.133
N32 Other disorders of bladder	0.867	0.133
R50-R69 General symptoms and signs	0.866	0.134
J00-J06 Acute upper respiratory infections	0.865	0.135
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.864	0.136
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.864	0.136
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.861	0.139
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.860	0.140
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.858	0.142
N00-N08 Glomerular diseases	0.857	0.143
K59 Other functional intestinal disorders	0.855	0.145
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.854	0.146
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.850	0.150
E20-E35 Disorders of other endocrine glands	0.849	0.151
J18.9 Pneumonia, unspecified	0.847	0.153
O80-O84 Delivery	0.846	0.154
R01 Cardiac murmurs and other cardiac sounds	0.846	0.154
J90-J94 Other diseases of pleura	0.846	0.154
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.845	0.155
K59.0 Constipation	0.844	0.156
R02 Gangrene, not elsewhere classified	0.844	0.156
N40-N51 Diseases of male genital organs	0.840	0.160
N18 Chronic renal failure	0.837	0.163
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.837	0.163
R00.0 Tachycardia, unspecified	0.834	0.166
O63 Long labour	0.834	0.166
R51 Headache	0.828	0.172
M20.5 Other deformities of toe(s) (acquired)	0.825	0.175
R26.8 Other and unspecified abnormalities of gait and mobility	0.825	0.175
N32.8 Other specified disorders of bladder	0.823	0.177
C15-C26 Malignant neoplasms of digestive organs	0.822	0.178
S62 Fracture at wrist and hand level	0.820	0.180
M80 Osteoporosis with pathological fracture	0.818	0.182
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.816	0.184
Chapter VI Diseases of the nervous system	0.813	0.187
C43-C44 Melanoma and other malignant neoplasms of skin	0.807	0.193
O20-O29 Other maternal disorders predominantly related to pregnancy	0.802	0.198
R41 Other symptoms and signs involving cognitive functions and awareness	0.802	0.198
R04.2 Haemoptysis	0.802	0.198
K60 Fissure and fistula of anal and rectal regions	0.802	0.198
I30-I52 Other forms of heart disease	0.801	0.199
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.801	0.199
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.799	0.201
N10-N16 Renal tubulo-interstitial diseases	0.797	0.203
N45 Orchitis and epididymitis	0.794	0.206
T79-T79 Certain early complications of trauma	0.793	0.207
H91 Other hearing loss	0.791	0.209
E50-E64 Other nutritional deficiencies	0.791	0.209
T66-T78 Other and unspecified effects of external causes	0.790	0.210
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.789	0.211
R90 Abnormal findings on diagnostic imaging of central nervous system	0.788	0.212
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.786	0.214
M20.6 Acquired deformity of toe(s), unspecified	0.783	0.217
I60-I69 Cerebrovascular diseases	0.783	0.217
R44 Other symptoms and signs involving general sensations and perceptions	0.783	0.217
C34 Malignant neoplasm of bronchus and lung	0.783	0.217
K35-K38 Diseases of appendix	0.782	0.218
C51-C58 Malignant neoplasms of female genital organs	0.781	0.219
O63.1 Prolonged second stage (of labour)	0.780	0.220
C50.4 Upper-outer quadrant of breast	0.779	0.221
R22.3 Localised swelling, mass and lump, upper limb	0.779	0.221
R06 Abnormalities of breathing	0.777	0.223
J20-J22 Other acute lower respiratory infections	0.776	0.224
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.774	0.226
J03 Acute tonsillitis	0.773	0.227
N60-N64 Disorders of breast	0.773	0.227
S50-S59 Injuries to the elbow and forearm	0.772	0.228
Chapter VII Diseases of the eye and adnexa	0.771	0.229
M23 Internal derangement of knee	0.770	0.230
S32 Fracture of lumbar spine and pelvis	0.768	0.232
S66 Injury of muscle and tendon at wrist and hand level	0.768	0.232
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.766	0.234
I44 Atrioventricular and left bundle-branch block	0.765	0.235
I83 Varicose veins of lower extremities	0.765	0.235
R42 Dizziness and giddiness	0.765	0.235
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.760	0.240
O80 Single spontaneous delivery	0.760	0.240
J30-J39 Other diseases of upper respiratory tract	0.759	0.241
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.758	0.242
R03 Abnormal blood-pressure reading, without diagnosis	0.757	0.243
D37-D48 Neoplasms of uncertain or unknown behaviour	0.755	0.245
K61 Abscess of anal and rectal regions	0.754	0.246
N80-N98 Noninflammatory disorders of female genital tract	0.752	0.248
S62.6 Fracture of other finger	0.751	0.249
Chapter XXI Factors influencing health status and contact with health services	0.751	0.249
J60-J70 Lung diseases due to external agents	0.750	0.250
K56 Paralytic ileus and intestinal obstruction without hernia	0.750	0.250
C20 Malignant neoplasm of rectum	0.750	0.250
M47 Spondylosis	0.749	0.251
I80 Phlebitis and thrombophlebitis	0.748	0.252
J18.0 Bronchopneumonia, unspecified	0.747	0.253
M40-M43 Deforming dorsopathies	0.747	0.253
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.746	0.254
D10-D36 Benign neoplasms	0.745	0.255
C50.3 Lower-inner quadrant of breast	0.745	0.255
R30 Pain associated with micturition	0.744	0.256
T93 Sequelae of injuries of lower limb	0.744	0.256
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.743	0.257
S02 Fracture of skull and facial bones	0.741	0.259
N36 Other disorders of urethra	0.741	0.259
R01.1 Cardiac murmur, unspecified	0.738	0.262
C50.5 Lower-outer quadrant of breast	0.738	0.262
T15-T19 Effects of foreign body entering through natural orifice	0.738	0.262
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.736	0.264
R35 Polyuria	0.736	0.264
S64 Injury of nerves at wrist and hand level	0.735	0.265
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.734	0.266
R09.1 Pleurisy	0.734	0.266
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.733	0.267
M86-M90 Other osteopathies	0.733	0.267
D36 Benign neoplasm of other and unspecified sites	0.731	0.269
H92 Otalgia and effusion of ear	0.731	0.269
S70-S79 Injuries to the hip and thigh	0.729	0.270
M81 Osteoporosis without pathological fracture	0.729	0.271
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.728	0.271
M65-M68 Disorders of synovium and tendon	0.727	0.273
H90 Conductive and sensorineural hearing loss	0.727	0.273
H30-H36 Disorders of choroid and retina	0.725	0.275
J90 Pleural effusion, not elsewhere classified	0.725	0.275
N18.9 Chronic renal failure, unspecified	0.724	0.276
R53 Malaise and fatigue	0.723	0.277
M48 Other spondylopathies	0.723	0.277
H60-H62 Diseases of external ear	0.722	0.278
H91.9 Hearing loss, unspecified	0.721	0.279
D36.1 Peripheral nerves and autonomic nervous system	0.721	0.279
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.721	0.279
S90-S99 Injuries to the ankle and foot	0.721	0.279
N84 Polyp of female genital tract	0.718	0.282
K90-K93 Other diseases of the digestive system	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
S09 Other and unspecified injuries of head	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
R92 Abnormal findings on diagnostic imaging of breast	0.715	0.284
R45 Symptoms and signs involving emotional state	0.715	0.285
Chapter V Mental and behavioural disorders	0.714	0.286
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.713	0.287
M20.4 Other hammer toe(s) (acquired)	0.713	0.287
O46 Antepartum haemorrhage, not elsewhere classified	0.713	0.287
M85 Other disorders of bone density and structure	0.712	0.288
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.711	0.289
R93.6 Abnormal findings on diagnostic imaging of limbs	0.711	0.289
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.711	0.289
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.711	0.289
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.711	0.289
S00 Superficial injury of head	0.710	0.290
R58 Haemorrhage, not elsewhere classified	0.709	0.291
S20-S29 Injuries to the thorax	0.707	0.293
N03 Chronic nephritic syndrome	0.707	0.293
J03.9 Acute tonsillitis, unspecified	0.707	0.293
M20.1 Hallux valgus (acquired)	0.705	0.295
R40 Somnolence, stupor and coma	0.704	0.296
N84.1 Polyp of cervix uteri	0.704	0.296
J40-J47 Chronic lower respiratory diseases	0.702	0.298
O63.9 Long labour, unspecified	0.702	0.298
R22.4 Localised swelling, mass and lump, lower limb	0.702	0.298
A50-A64 Infections with a predominantly sexual mode of transmission	0.701	0.299
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.701	0.299
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.701	0.299
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.701	0.299
C40-C41 Malignant neoplasms of bone and articular cartilage	0.701	0.299
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.701	0.299
S62.60 Fracture of other finger (closed)	0.701	0.299
N32.3 Diverticulum of bladder	0.701	0.299
J13 Pneumonia due to Streptococcus pneumoniae	0.700	0.299
J17 Pneumonia in diseases classified elsewhere	0.700	0.300
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.700	0.300
J15 Bacterial pneumonia, not elsewhere classified	0.700	0.300
J12 Viral pneumonia, not elsewhere classified	0.700	0.300
J11 Influenza, virus not identified	0.700	0.300
J10 Influenza due to identified influenza virus	0.700	0.300
J14 Pneumonia due to Haemophilus influenzae	0.700	0.300
J09 Influenza due to certain identified influenza virus	0.700	0.300
R22.0 Localised swelling, mass and lump, head	0.700	0.300
E53 Deficiency of other B group vitamins	0.698	0.301
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.698	0.302
M91-M94 Chondropathies	0.698	0.302
M60-M63 Disorders of muscles	0.698	0.302
M00-M03 Infectious arthropathies	0.698	0.302
K56.5 Intestinal adhesions [bands] with obstruction	0.697	0.303
R36 Urethral discharge	0.697	0.303
R34 Anuria and oliguria	0.697	0.303
I86 Varicose veins of other sites	0.697	0.303
I63 Cerebral infarction	0.696	0.304
H93 Other disorders of ear, not elsewhere classified	0.695	0.305
N08 Glomerular disorders in diseases classified elsewhere	0.694	0.305
I85 Oesophageal varices	0.694	0.306
N13 Obstructive and reflux uropathy	0.694	0.306
A30-A49 Other bacterial diseases	0.693	0.307
O85-O92 Complications predominantly related to the puerperium	0.693	0.307
E40-E46 Malnutrition	0.693	0.307
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.692	0.308
R00.2 Palpitations	0.691	0.309
J18.8 Other pneumonia, organism unspecified	0.690	0.309
J18.2 Hypostatic pneumonia, unspecified	0.690	0.309
R26.3 Immobility	0.690	0.310
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.690	0.310
N19 Unspecified renal failure	0.690	0.310
K60.2 Anal fissure, unspecified	0.689	0.311
R04.9 Haemorrhage from respiratory passages, unspecified	0.689	0.311
R04.8 Haemorrhage from other sites in respiratory passages	0.689	0.311
R04.1 Haemorrhage from throat	0.689	0.311
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.689	0.311
Chapter XX External causes of morbidity and mortality	0.689	0.311
S40-S49 Injuries to the shoulder and upper arm	0.688	0.312
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.687	0.312
N86 Erosion and ectropion of cervix uteri	0.687	0.313
C50.9 Breast, unspecified	0.686	0.314
T51 Toxic effect of alcohol	0.685	0.315
I51 Complications and ill-defined descriptions of heart disease	0.685	0.315
E28 Ovarian dysfunction	0.684	0.316
N42 Other disorders of prostate	0.683	0.317
B99-B99 Other infectious diseases	0.683	0.317
B90-B94 Sequelae of infectious and parasitic diseases	0.683	0.317
B85-B89 Pediculosis, acariasis and other infestations	0.683	0.317
B65-B83 Helminthiases	0.683	0.317
B50-B64 Protozoal diseases	0.683	0.317
B20-B24 Human immunodeficiency virus [HIV] disease	0.683	0.317
B15-B19 Viral hepatitis	0.683	0.317
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.683	0.317
A80-A89 Viral infections of the central nervous system	0.683	0.317
A75-A79 Rickettsioses	0.683	0.317
A70-A74 Other diseases caused by chlamydiae	0.683	0.317
A65-A69 Other spirochaetal diseases	0.683	0.317
A20-A28 Certain zoonotic bacterial diseases	0.683	0.317
A15-A19 Tuberculosis	0.683	0.317
C34.1 Upper lobe, bronchus or lung	0.683	0.317
M80.0 Postmenopausal osteoporosis with pathological fracture	0.681	0.319
I44.1 Atrioventricular block, second degree	0.680	0.320
D00-D09 In situ neoplasms	0.679	0.320
C50.2 Upper-inner quadrant of breast	0.677	0.323
I95-I99 Other and unspecified disorders of the circulatory system	0.677	0.323
I87 Other disorders of veins	0.676	0.324
E21.3 Hyperparathyroidism, unspecified	0.676	0.324
N18.0 End-stage renal disease	0.676	0.324
R46 Symptoms and signs involving appearance and behaviour	0.675	0.325
R43 Disturbances of smell and taste	0.675	0.325
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.674	0.326
B97 Viral agents as the cause of diseases classified to other chapters	0.673	0.327
R32 Unspecified urinary incontinence	0.672	0.328
S80-S89 Injuries to the knee and lower leg	0.672	0.328
G30-G32 Other degenerative diseases of the nervous system	0.671	0.329
H33 Retinal detachments and breaks	0.671	0.329
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.670	0.330
K60.3 Anal fistula	0.669	0.330
I45 Other conduction disorders	0.669	0.331
M80.9 Unspecified osteoporosis with pathological fracture	0.669	0.331
S06 Intracranial injury	0.668	0.332
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.667	0.333
M34 Systemic sclerosis	0.667	0.333
M33 Dermatopolymyositis	0.667	0.333
M32 Systemic lupus erythematosus	0.667	0.333
M31 Other necrotising vasculopathies	0.667	0.333
M30 Polyarteritis nodosa and related conditions	0.667	0.333
M21 Other acquired deformities of limbs	0.667	0.333
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.667	0.333
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.666	0.333
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.666	0.333
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.666	0.333
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.666	0.333
K92 Other diseases of digestive system	0.666	0.334
R52 Pain, not elsewhere classified	0.665	0.335
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.665	0.335
H80-H83 Diseases of inner ear	0.664	0.335
M20.2 Hallux rigidus	0.664	0.336
J95-J99 Other diseases of the respiratory system	0.664	0.336
O23 Infections of genito-urinary tract in pregnancy	0.664	0.336
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.663	0.337
N05 Unspecified nephritic syndrome	0.663	0.337
R47-R49 Symptoms and signs involving speech and voice	0.662	0.337
E27 Other disorders of adrenal gland	0.662	0.338
C44 Other malignant neoplasms of skin	0.661	0.339
C56 Malignant neoplasm of ovary	0.659	0.341
S69 Other and unspecified injuries of wrist and hand	0.658	0.342
S67 Crushing injury of wrist and hand	0.658	0.342
S65 Injury of blood vessels at wrist and hand level	0.658	0.342
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.658	0.342
S60 Superficial injury of wrist and hand	0.658	0.342
N37 Urethral disorders in diseases classified elsewhere	0.658	0.342
N34 Urethritis and urethral syndrome	0.658	0.342
N33 Bladder disorders in diseases classified elsewhere	0.658	0.342
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.657	0.342
R27 Other lack of coordination	0.657	0.343
N99-N99 Other disorders of the genitourinary system	0.656	0.344
K61.0 Anal abscess	0.656	0.344
I44.0 Atrioventricular block, first degree	0.655	0.345
G35-G37 Demyelinating diseases of the central nervous system	0.655	0.345
N32.9 Bladder disorder, unspecified	0.653	0.347
S51 Open wound of forearm	0.653	0.347
S32.5 Fracture of pubis	0.652	0.348
R54 Senility	0.652	0.348
M84 Disorders of continuity of bone	0.650	0.349
M83 Adult osteomalacia	0.650	0.349
M82 Osteoporosis in diseases classified elsewhere	0.650	0.349
K70-K77 Diseases of liver	0.650	0.350
J02 Acute pharyngitis	0.650	0.350
M47.9 Spondylosis, unspecified	0.650	0.350
O46.9 Antepartum haemorrhage, unspecified	0.650	0.350
N18.3 Chronic kidney disease, stage 3	0.650	0.350
O63.0 Prolonged first stage (of labour)	0.649	0.350
S01 Open wound of head	0.648	0.352
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.648	0.352
O80.9 Single spontaneous delivery, unspecified	0.648	0.352
N39 Other disorders of urinary system	0.648	0.352
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.648	0.352
M20.3 Other deformity of hallux (acquired)	0.647	0.353
M20.0 Deformity of finger(s)	0.647	0.353
R00.8 Other and unspecified abnormalities of heart beat	0.646	0.354
I44.7 Left bundle-branch block, unspecified	0.646	0.354
T79 Certain early complications of trauma, not elsewhere classified	0.645	0.355
I00-I02 Acute rheumatic fever	0.645	0.355
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.645	0.355
R06.8 Other and unspecified abnormalities of breathing	0.645	0.355
T90 Sequelae of injuries of head	0.645	0.355
N18.4 Chronic kidney disease, stage 4	0.644	0.355
S08 Traumatic amputation of part of head	0.643	0.357
S07 Crushing injury of head	0.643	0.357
S05 Injury of eye and orbit	0.643	0.357
S04 Injury of cranial nerves	0.643	0.357
S03 Dislocation, sprain and strain of joints and ligaments of head	0.643	0.357
M22 Disorders of patella	0.643	0.357
E23 Hypofunction and other disorders of pituitary gland	0.642	0.358
O94-O99 Other obstetric conditions, not elsewhere classified	0.641	0.358
K36 Other appendicitis	0.641	0.359
O80.0 Spontaneous vertex delivery	0.641	0.359
T78 Adverse effects, not elsewhere classified	0.641	0.359
C34.9 Bronchus or lung, unspecified	0.639	0.361
J06 Acute upper respiratory infections of multiple and unspecified sites	0.639	0.361
J91 Pleural effusion in conditions classified elsewhere	0.639	0.361
D70-D77 Other diseases of blood and blood-forming organs	0.639	0.361
K92.0 Haematemesis	0.639	0.361
T40.2 Other opioids	0.639	0.361
I05-I09 Chronic rheumatic heart diseases	0.638	0.362
M45 Ankylosing spondylitis	0.638	0.362
R44.1 Visual hallucinations	0.638	0.362
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.638	0.362
N18.5 Chronic kidney disease, stage 5	0.638	0.362
Z92 Personal history of medical treatment	0.638	0.362
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.637	0.362
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.637	0.362
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.637	0.362
T46 Poisoning by agents primarily affecting the cardiovascular system	0.637	0.362
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.637	0.362
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.637	0.362
T41 Poisoning by anaesthetics and therapeutic gases	0.637	0.362
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.637	0.362
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.637	0.362
T36 Poisoning by systemic antibiotics	0.637	0.362
T93.1 Sequelae of fracture of femur	0.637	0.363
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.637	0.363
H94 Other disorders of ear in diseases classified elsewhere	0.637	0.363
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.637	0.363
K35 Acute appendicitis	0.635	0.365
S68 Traumatic amputation of wrist and hand	0.635	0.365
K65-K67 Diseases of peritoneum	0.635	0.365
R39 Other symptoms and signs involving the urinary system	0.634	0.366
H34 Retinal vascular occlusions	0.634	0.366
O68 Labour and delivery complicated by foetal stress [distress]	0.633	0.367
B35-B49 Mycoses	0.633	0.367
G90-G99 Other disorders of the nervous system	0.632	0.368
E53.8 Deficiency of other specified B group vitamins	0.632	0.368
D22 Melanocytic naevi	0.631	0.369
C50.6 Axillary tail of breast	0.631	0.369
C50.0 Nipple and areola	0.631	0.369
R23 Other skin changes	0.630	0.370
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.629	0.371
R41.0 Disorientation, unspecified	0.629	0.371
O42 Premature rupture of membranes	0.627	0.373
K60.1 Chronic anal fissure	0.626	0.374
M49 Spondylopathies in diseases classified elsewhere	0.626	0.374
M46 Other inflammatory spondylopathies	0.626	0.374
M25 Other joint disorders, not elsewhere classified	0.626	0.374
K64 Haemorrhoids and perianal venous thrombosis	0.625	0.375
Z91 Personal history of risk-factors, not elsewhere classified	0.625	0.375
E65-E68 Obesity and other hyperalimentation	0.624	0.375
R03.1 Nonspecific low blood-pressure reading	0.624	0.376
R26.2 Difficulty in walking, not elsewhere classified	0.624	0.376
R26.1 Paralytic gait	0.624	0.376
R26.0 Ataxic gait	0.624	0.376
J80-J84 Other respiratory diseases principally affecting the interstitium	0.624	0.376
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.623	0.377
C19 Malignant neoplasm of rectosigmoid junction	0.622	0.377
E21.0 Primary hyperparathyroidism	0.622	0.378
Z86 Personal history of certain other diseases	0.622	0.378
O75 Other complications of labour and delivery, not elsewhere classified	0.622	0.378
O74 Complications of anaesthesia during labour and delivery	0.622	0.378
O73 Retained placenta and membranes, without haemorrhage	0.622	0.378
O71 Other obstetric trauma	0.622	0.378
O69 Labour and delivery complicated by umbilical cord complications	0.622	0.378
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.622	0.378
O66 Other obstructed labour	0.622	0.378
O65 Obstructed labour due to maternal pelvic abnormality	0.622	0.378
O64 Obstructed labour due to malposition and malpresentation of foetus	0.622	0.378
O62 Abnormalities of forces of labour	0.622	0.378
O61 Failed induction of labour	0.622	0.378
O60 Preterm delivery	0.622	0.378
N32.4 Rupture of bladder, nontraumatic	0.622	0.378
N32.2 Vesical fistula, not elsewhere classified	0.622	0.378
N32.1 Vesicointestinal fistula	0.622	0.378
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.621	0.379
J43 Emphysema	0.621	0.379
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.621	0.379
E61 Deficiency of other nutrient elements	0.621	0.379
R68 Other general symptoms and signs	0.621	0.379
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.621	0.379
R62 Lack of expected normal physiological development	0.621	0.379
R57 Shock, not elsewhere classified	0.621	0.379
R64 Cachexia	0.621	0.379
N36.2 Urethral caruncle	0.621	0.379
J92 Pleural plaque	0.620	0.380
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.620	0.380
J04 Acute laryngitis and tracheitis	0.620	0.380
J01 Acute sinusitis	0.620	0.380
J22 Unspecified acute lower respiratory infection	0.620	0.380
K40-K46 Hernia	0.620	0.380
T85 Complications of other internal prosthetic devices, implants and grafts	0.620	0.380
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.619	0.380
C38 Malignant neoplasm of heart, mediastinum and pleura	0.619	0.380
C32 Malignant neoplasm of larynx	0.619	0.380
C31 Malignant neoplasm of accessory sinuses	0.619	0.380
C30 Malignant neoplasm of nasal cavity and middle ear	0.619	0.380
C37 Malignant neoplasm of thymus	0.619	0.380
C33 Malignant neoplasm of trachea	0.619	0.380
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.619	0.381
S37 Injury of urinary and pelvic organs	0.619	0.381
S36 Injury of intra-abdominal organs	0.619	0.381
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.619	0.381
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.619	0.381
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.619	0.381
S31 Open wound of abdomen, lower back and pelvis	0.619	0.381
S30 Superficial injury of abdomen, lower back and pelvis	0.619	0.381
N40 Hyperplasia of prostate	0.618	0.382
M05-M14 Inflammatory polyarthropathies	0.618	0.382
H92.0 Otalgia	0.618	0.382
R09.3 Abnormal sputum	0.617	0.383
R09.2 Respiratory arrest	0.617	0.383
R09.0 Asphyxia	0.617	0.383
I64 Stroke, not specified as haemorrhage or infarction	0.617	0.383
C60-C63 Malignant neoplasms of male genital organs	0.617	0.383
H43-H45 Disorders of vitreous body and globe	0.616	0.383
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.616	0.384
C43 Malignant melanoma of skin	0.616	0.384
T98 Sequelae of other and unspecified effects of external causes	0.615	0.385
T95 Sequelae of burns, corrosions and frostbite	0.615	0.385
T94 Sequelae of injuries involving multiple and unspecified body regions	0.615	0.385
T92 Sequelae of injuries of upper limb	0.615	0.385

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations