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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115352742
log Bayes Factor = 19.2314
Chromosome 5   position 133,828,896  (GRCh37) Explore rs115352742 on Ensembl!
Variant rs115352742 is part of Cluster X0143

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
M25 Other joint disorders, not elsewhere classified
0.997 0.003 0.000
M54 Dorsalgia
0.997 0.003 0.000
R06 Abnormalities of breathing
0.996 0.004 0.000
J34 Other disorders of nose and nasal sinuses
0.994 0.006 0.000
R06.0 Dyspnoea
0.994 0.006 0.000
M54.2 Cervicalgia
0.987 0.013 0.000
M25.5 Pain in joint
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.984 0.016 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.982 0.018 0.000
J20-J22 Other acute lower respiratory infections
0.981 0.019 0.000
B95-B98 Bacterial, viral and other infectious agents
0.980 0.020 0.000
R00 Abnormalities of heart beat
0.979 0.021 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.975 0.025 0.000
M54.22 Cervicalgia (Cervical region)
0.973 0.027 0.000
M54.5 Low back pain
0.972 0.028 0.000
M70-M79 Other soft tissue disorders
0.972 0.028 0.000
S50-S59 Injuries to the elbow and forearm
0.970 0.030 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.969 0.031 0.000
S80-S89 Injuries to the knee and lower leg
0.968 0.032 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.967 0.033 0.000
J22 Unspecified acute lower respiratory infection
0.965 0.035 0.000
M25.51 Pain in joint (Shoulder region)
0.962 0.038 0.000
I60-I69 Cerebrovascular diseases
0.961 0.039 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.959 0.041 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.958 0.042 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.953 0.047 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.952 0.048 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.947 0.053 0.000
S52 Fracture of forearm
0.947 0.053 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.946 0.054 0.000
D69 Purpura and other haemorrhagic conditions
0.944 0.056 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.936 0.064 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.936 0.064 0.000
M80-M85 Disorders of bone density and structure
0.935 0.065 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.932 0.068 0.000
Chapter XXII Codes for special purposes
0.932 0.068 0.000
I71 Aortic aneurysm and dissection
0.931 0.069 0.000
D68 Other coagulation defects
0.927 0.073 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.924 0.076 0.000
Chapter II Neoplasms
0.924 0.076 0.000
Z22 Carrier of infectious disease
0.922 0.078 0.000
M54.59 Low back pain (Site unspecified)
0.922 0.078 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.920 0.080 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.916 0.084 0.000
R07 Pain in throat and chest
0.915 0.085 0.000
D69.6 Thrombocytopenia, unspecified
0.911 0.089 0.000
J34.3 Hypertrophy of nasal turbinates
0.911 0.089 0.000
M25.4 Effusion of joint
0.911 0.089 0.000
R10 Abdominal and pelvic pain
0.910 0.090 0.000
J31.0 Chronic rhinitis
0.909 0.091 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.909 0.091 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.907 0.093 0.000
R07.2 Precordial pain
0.902 0.098 0.000
R10.3 Pain localised to other parts of lower abdomen
0.901 0.099 0.000
I63 Cerebral infarction
0.899 0.101 0.000
Z22.3 Carrier of other specified bacterial diseases
0.898 0.102 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.894 0.106 0.000
R06.5 Mouth breathing
0.893 0.107 0.000
Z51 Other medical care
0.892 0.108 0.000
R00.2 Palpitations
0.892 0.108 0.000
S52.0 Fracture of upper end of ulna
0.891 0.109 0.000
M79.0 Rheumatism, unspecified
0.890 0.110 0.000
J35 Chronic diseases of tonsils and adenoids
0.889 0.111 0.000
I05-I09 Chronic rheumatic heart diseases
0.888 0.112 0.000
Z51.5 Palliative care
0.887 0.113 0.000
M79.6 Pain in limb
0.887 0.113 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.887 0.113 0.000
R21 Rash and other nonspecific skin eruption
0.887 0.113 0.000
I99 Other and unspecified disorders of circulatory system
0.886 0.114 0.000
S40-S49 Injuries to the shoulder and upper arm
0.885 0.115 0.000
A00-A09 Intestinal infectious diseases
0.885 0.115 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.883 0.117 0.000
R00.0 Tachycardia, unspecified
0.881 0.119 0.000
R10.1 Pain localised to upper abdomen
0.880 0.120 0.000
I26 Pulmonary embolism
0.879 0.121 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.874 0.126 0.000
B15-B19 Viral hepatitis
0.873 0.126 0.000
S20-S29 Injuries to the thorax
0.871 0.129 0.000
Z47 Other orthopaedic follow-up care
0.866 0.134 0.000
S52.1 Fracture of upper end of radius
0.863 0.137 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.860 0.140 0.000
M54.29 Cervicalgia-Site unspe
0.859 0.141 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.855 0.145 0.000
J32 Chronic sinusitis
0.855 0.145 0.000
I63.9 Cerebral infarction, unspecified
0.855 0.145 0.000
R47-R49 Symptoms and signs involving speech and voice
0.854 0.146 0.000
J90-J94 Other diseases of pleura
0.853 0.147 0.000
I80 Phlebitis and thrombophlebitis
0.852 0.148 0.000
S52.00 Fracture of upper end of ulna (closed)
0.851 0.149 0.000
M80 Osteoporosis with pathological fracture
0.850 0.150 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.848 0.152 0.000
C51-C58 Malignant neoplasms of female genital organs
0.848 0.152 0.000
J39 Other diseases of upper respiratory tract
0.848 0.152 0.000
U80 Agent resistant to penicillin and related antibiotics
0.848 0.152 0.000
S89 Other and unspecified injuries of lower leg
0.844 0.156 0.000
R73 Elevated blood glucose level
0.844 0.156 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.844 0.156 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.844 0.156 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.843 0.157 0.000
I70 Atherosclerosis
0.842 0.158 0.000
I74 Arterial embolism and thrombosis
0.840 0.160 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.839 0.161 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.839 0.161 0.000
S60-S69 Injuries to the wrist and hand
0.836 0.164 0.000
M25.46 Effusion of joint (Lower leg)
0.836 0.164 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.832 0.168 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.831 0.169 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.828 0.172 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.828 0.172 0.000
S90-S99 Injuries to the ankle and foot
0.827 0.173 0.000
Z13 Special screening examination for other diseases and disorders
0.827 0.173 0.000
R18 Ascites
0.822 0.178 0.000
Z51.8 Other specified medical care
0.821 0.179 0.000
M86-M90 Other osteopathies
0.821 0.179 0.000
D68.2 Hereditary deficiency of other clotting factors
0.818 0.182 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.818 0.182 0.000
I82 Other venous embolism and thrombosis
0.818 0.182 0.000
I77 Other disorders of arteries and arterioles
0.817 0.183 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.816 0.184 0.000
Z50 Care involving use of rehabilitation procedures
0.816 0.184 0.000
M25.7 Osteophyte
0.813 0.187 0.000
M79.62 Pain in limb (Upper arm)
0.812 0.188 0.000
T66-T78 Other and unspecified effects of external causes
0.810 0.190 0.000
I72 Other aneurysm
0.810 0.190 0.000
M24 Other specific joint derangements
0.810 0.190 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.809 0.191 0.000
M54.56 Low back pain (Lumbar region)
0.807 0.193 0.000
J60-J70 Lung diseases due to external agents
0.807 0.193 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.805 0.195 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.805 0.195 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.804 0.196 0.000
S52.10 Fracture of upper end of radius (closed)
0.803 0.197 0.000
M25.3 Other instability of joint
0.801 0.199 0.000
J33 Nasal polyp
0.801 0.199 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.800 0.200 0.000
M79.8 Other specified soft tissue disorders
0.800 0.200 0.000
R00.1 Bradycardia, unspecified
0.799 0.201 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.799 0.201 0.000
U80.1 Methicillin resistant agent
0.796 0.204 0.000
C56 Malignant neoplasm of ovary
0.796 0.204 0.000
E65-E68 Obesity and other hyperalimentation
0.795 0.205 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.795 0.205 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.795 0.205 0.000
A04 Other bacterial intestinal infections
0.791 0.209 0.000
I27 Other pulmonary heart diseases
0.790 0.210 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.788 0.212 0.000
T43.2 Other and unspecified antidepressants
0.788 0.212 0.000
M25.8 Other specified joint disorders
0.787 0.213 0.000
R73.0 Abnormal glucose tolerance test
0.787 0.213 0.000
M79.66 Pain in limb (Lower leg)
0.786 0.214 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.785 0.215 0.000
J34.2 Deviated nasal septum
0.784 0.216 0.000
I87 Other disorders of veins
0.783 0.217 0.000
M54.57 Low back pain (Lumbosacral region)
0.783 0.217 0.000
Z48 Other surgical follow-up care
0.783 0.217 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.782 0.218 0.000
M25.50 Pain in joint (Multiple sites)
0.780 0.220 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.779 0.221 0.000
J30 Vasomotor and allergic rhinitis
0.779 0.221 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.779 0.221 0.000
C79 Secondary malignant neoplasm of other sites
0.778 0.222 0.000
M54.6 Pain in thoracic spine
0.777 0.223 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.775 0.225 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.773 0.227 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.773 0.227 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.772 0.228 0.000
E66 Obesity
0.772 0.228 0.000
S52.6 Fracture of lower end of both ulna and radius
0.771 0.229 0.000
M71 Other bursopathies
0.770 0.230 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.768 0.232 0.000
M54.1 Radiculopathy
0.768 0.232 0.000
B35-B49 Mycoses
0.768 0.232 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.767 0.233 0.000
R06.4 Hyperventilation
0.766 0.234 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.764 0.236 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.763 0.237 0.000
S83.2 Tear of meniscus, current
0.762 0.238 0.000
Z29 Need for other prophylactic measures
0.761 0.239 0.000
M35 Other systemic involvement of connective tissue
0.760 0.240 0.000
M50 Cervical disk disorders
0.759 0.241 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.759 0.241 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.758 0.242 0.000
C78.2 Secondary malignant neoplasm of pleura
0.758 0.242 0.000
D60-D64 Aplastic and other anaemias
0.757 0.243 0.000
J93 Pneumothorax
0.757 0.243 0.000
S89.9 Unspecified injury of lower leg
0.756 0.244 0.000
I78 Diseases of capillaries
0.755 0.244 0.000
M85 Other disorders of bone density and structure
0.755 0.245 0.000
D68.0 Von Willebrand's disease
0.754 0.245 0.000
S42 Fracture of shoulder and upper arm
0.754 0.246 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.753 0.247 0.000
S86 Injury of muscle and tendon at lower leg level
0.752 0.248 0.000
M60-M63 Disorders of muscles
0.751 0.249 0.000
M25.52 Pain in joint (Upper arm)
0.751 0.249 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.750 0.250 0.000
M05-M14 Inflammatory polyarthropathies
0.749 0.251 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.749 0.251 0.000
E66.8 Other obesity
0.748 0.252 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.748 0.252 0.000
C80 Malignant neoplasm without specification of site
0.748 0.252 0.000
S62 Fracture at wrist and hand level
0.748 0.252 0.000
J35.0 Chronic tonsillitis
0.748 0.252 0.000
Z04 Examination and observation for other reasons
0.747 0.253 0.000
M21 Other acquired deformities of limbs
0.746 0.254 0.000
D68.8 Other specified coagulation defects
0.746 0.254 0.000
I08 Multiple valve diseases
0.745 0.255 0.000
A80-A89 Viral infections of the central nervous system
0.744 0.256 0.000
R06.1 Stridor
0.744 0.256 0.000
D68.9 Coagulation defect, unspecified
0.743 0.257 0.000
I69 Sequelae of cerebrovascular disease
0.742 0.258 0.000
Z50.1 Other physical therapy
0.741 0.259 0.000
I84 Haemorrhoids
0.740 0.260 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.740 0.260 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.739 0.261 0.000
J20 Acute bronchitis
0.738 0.262 0.000
S70-S79 Injuries to the hip and thigh
0.737 0.263 0.000
B18 Chronic viral hepatitis
0.736 0.264 0.000
S81 Open wound of lower leg
0.735 0.264 0.000
C78.7 Secondary malignant neoplasm of liver
0.735 0.265 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.735 0.265 0.000
I85 Oesophageal varices
0.734 0.265 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.731 0.269 0.000
M25.53 Pain in joint (Forearm)
0.730 0.270 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.730 0.270 0.000
B25-B34 Other viral diseases
0.729 0.271 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.728 0.272 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.727 0.273 0.000
I71.0 Dissection of aorta [any part]
0.727 0.273 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.273 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.726 0.274 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.726 0.274 0.000
I05 Rheumatic mitral valve diseases
0.725 0.275 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.725 0.275 0.000
A08 Viral and other specified intestinal infections
0.724 0.276 0.000
S10-S19 Injuries to the neck
0.723 0.276 0.000
R77 Other abnormalities of plasma proteins
0.723 0.277 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.723 0.277 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.722 0.278 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.721 0.279 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.721 0.279 0.000
I61 Intracerebral haemorrhage
0.720 0.280 0.000
R45 Symptoms and signs involving emotional state
0.719 0.281 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.718 0.282 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
J37 Chronic laryngitis and laryngotracheitis
0.717 0.283 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
M25.9 Joint disorder, unspecified
0.715 0.285 0.000
M25.2 Flail joint
0.715 0.285 0.000
M25.1 Fistula of joint
0.715 0.285 0.000
M25.0 Haemarthrosis
0.715 0.285 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.715 0.285 0.000
M54.8 Other dorsalgia
0.715 0.285 0.000
M54.0 Panniculitis affecting regions of neck and back
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.285 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.714 0.285 0.000
M89 Other disorders of bone
0.714 0.286 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
S50 Superficial injury of forearm
0.714 0.286 0.000
R06.7 Sneezing
0.714 0.286 0.000
R06.6 Hiccough
0.714 0.286 0.000
R06.3 Periodic breathing
0.714 0.286 0.000
B16 Acute hepatitis B
0.713 0.287 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.712 0.287 0.000
J39.2 Other diseases of pharynx
0.712 0.288 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.710 0.290 0.000
M25.54 Pain in joint (Hand)
0.708 0.292 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.708 0.292 0.000
M54.27 Cervicalgia-Lumbosacral
0.708 0.292 0.000
M54.26 Cervicalgia-Lumbar
0.708 0.292 0.000
M54.25 Cervicalgia-Thoracolumbar
0.708 0.292 0.000
M54.24 Cervicalgia-Thoracic
0.708 0.292 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.708 0.292 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.708 0.292 0.000
M54.20 Cervicalgia-Mult site
0.708 0.292 0.000
I83 Varicose veins of lower extremities
0.708 0.292 0.000
M25.59 Pain in joint (Site unspecified)
0.708 0.292 0.000
M25.58 Pain in joint (Other)
0.708 0.292 0.000
Z47.8 Other specified orthopaedic follow-up care
0.707 0.293 0.000
Chapter VIII Diseases of the ear and mastoid process
0.707 0.293 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.294 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.705 0.295 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.705 0.295 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
J21 Acute bronchiolitis
0.703 0.297 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.702 0.298 0.000
S51 Open wound of forearm
0.701 0.299 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.701 0.299 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.701 0.299 0.000
M84 Disorders of continuity of bone
0.700 0.300 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.300 0.000
R47 Speech disturbances, not elsewhere classified
0.700 0.300 0.000
M25.47 Effusion of joint (Ankle and foot)
0.700 0.300 0.000
I30-I52 Other forms of heart disease
0.699 0.301 0.000
M79.7 Fibromyalgia
0.699 0.301 0.000
D67 Hereditary factor IX deficiency
0.699 0.301 0.000
D66 Hereditary factor VIII deficiency
0.699 0.301 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.699 0.301 0.000
M81 Osteoporosis without pathological fracture
0.697 0.303 0.000
M54.55 Low back pain (Thoracolumbar region)
0.697 0.303 0.000
M54.54 Low back pain-Thoracic
0.697 0.303 0.000
M54.53 Low back pain-Cervicothoracic
0.697 0.303 0.000
M54.52 Low back pain-Cervical
0.697 0.303 0.000
M54.51 Low back pain-Occipit-atl-axl
0.697 0.303 0.000
M53 Other dorsopathies, not elsewhere classified
0.697 0.303 0.000
M76 Enthesopathies of lower limb, excluding foot
0.697 0.303 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.697 0.303 0.000
S59 Other and unspecified injuries of forearm
0.695 0.304 0.000
S58 Traumatic amputation of forearm
0.695 0.304 0.000
S57 Crushing injury of forearm
0.695 0.304 0.000
S56 Injury of muscle and tendon at forearm level
0.695 0.304 0.000
S55 Injury of blood vessels at forearm level
0.695 0.304 0.000
S54 Injury of nerves at forearm level
0.695 0.304 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.695 0.304 0.000
M79.1 Myalgia
0.695 0.305 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.695 0.305 0.000
S88 Traumatic amputation of lower leg
0.694 0.306 0.000
S87 Crushing injury of lower leg
0.694 0.306 0.000
S85 Injury of blood vessels at lower leg level
0.694 0.306 0.000
S84 Injury of nerves at lower leg level
0.694 0.306 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.694 0.306 0.000
I88 Nonspecific lymphadenitis
0.693 0.306 0.000
I81 Portal vein thrombosis
0.693 0.306 0.000
M23 Internal derangement of knee
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.693 0.307 0.000
I82.8 Embolism and thrombosis of other specified veins
0.693 0.307 0.000
R17 Unspecified jaundice
0.691 0.309 0.000
M54.4 Lumbago with sciatica
0.691 0.309 0.000
R49 Voice disturbances
0.690 0.310 0.000
M25.77 Osteophyte (Ankle and foot)
0.690 0.310 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.311 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.689 0.311 0.000
M54.50 Low back pain (Multiple sites in spine)
0.689 0.311 0.000
C78.0 Secondary malignant neoplasm of lung
0.688 0.312 0.000
J32.9 Chronic sinusitis, unspecified
0.688 0.312 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.688 0.312 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.688 0.312 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.688 0.312 0.000
J35.1 Hypertrophy of tonsils
0.687 0.313 0.000
I62 Other nontraumatic intracranial haemorrhage
0.687 0.313 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.687 0.313 0.000
M79.9 Soft tissue disorder, unspecified
0.687 0.313 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.687 0.313 0.000
M79.3 Panniculitis, unspecified
0.687 0.313 0.000
M79.2 Neuralgia and neuritis, unspecified
0.687 0.313 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.686 0.314 0.000
M77 Other enthesopathies
0.686 0.314 0.000
J32.8 Other chronic sinusitis
0.685 0.315 0.000
Z22.5 Carrier of viral hepatitis
0.685 0.315 0.000
Z28 Immunisation not carried out
0.683 0.317 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.683 0.317 0.000
Z26 Need for immunisation against other single infectious diseases
0.683 0.317 0.000
Z25 Need for immunisation against other single viral diseases
0.683 0.317 0.000
Z24 Need for immunisation against certain single viral diseases
0.683 0.317 0.000
Z23 Need for immunisation against single bacterial diseases
0.683 0.317 0.000
Z20 Contact with and exposure to communicable diseases
0.683 0.317 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.683 0.317 0.000
B00 Herpesviral [herpes simplex] infections
0.682 0.318 0.000
A02 Other Salmonella infections
0.682 0.318 0.000
R76 Other abnormal immunological findings in serum
0.682 0.318 0.000
M31 Other necrotising vasculopathies
0.680 0.320 0.000
M22 Disorders of patella
0.680 0.320 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
J31.2 Chronic pharyngitis
0.679 0.321 0.000
J31.1 Chronic nasopharyngitis
0.679 0.321 0.000
S52.9 Fracture of forearm, part unspecified
0.679 0.321 0.000
S52.8 Fracture of other parts of forearm
0.679 0.321 0.000
S52.7 Multiple fractures of forearm
0.679 0.321 0.000
S52.4 Fracture of shafts of both ulna and radius
0.679 0.321 0.000
S52.3 Fracture of shaft of radius
0.679 0.321 0.000
S52.2 Fracture of shaft of ulna
0.679 0.321 0.000
I28 Other diseases of pulmonary vessels
0.678 0.322 0.000
Z51.9 Medical care, unspecified
0.678 0.322 0.000
D69.9 Haemorrhagic condition, unspecified
0.677 0.323 0.000
D69.8 Other specified haemorrhagic conditions
0.677 0.323 0.000
D69.5 Secondary thrombocytopenia
0.677 0.323 0.000
D69.4 Other primary thrombocytopenia
0.677 0.323 0.000
D69.2 Other nonthrombocytopenic purpura
0.677 0.323 0.000
D69.1 Qualitative platelet defects
0.677 0.323 0.000
D69.0 Allergic purpura
0.677 0.323 0.000
J32.2 Chronic ethmoidal sinusitis
0.676 0.324 0.000
J93.9 Pneumothorax, unspecified
0.676 0.324 0.000
M79.63 Pain in limb (Forearm)
0.676 0.324 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.676 0.324 0.000
M24.1 Other articular cartilage disorders
0.674 0.326 0.000
I95 Hypotension
0.673 0.327 0.000
M79.88 Other specified soft tissue disorders (Other)
0.673 0.327 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.672 0.328 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.672 0.328 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.672 0.328 0.000
S83.7 Injury to multiple structures of knee
0.671 0.329 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.671 0.329 0.000
S83.3 Tear of articular cartilage of knee, current
0.671 0.329 0.000
S83.1 Dislocation of knee
0.671 0.329 0.000
S83.0 Dislocation of patella
0.671 0.329 0.000
M54.9 Dorsalgia, unspecified
0.671 0.329 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.671 0.329 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.671 0.329 0.000
R71 Abnormality of red blood cells
0.671 0.329 0.000
M83 Adult osteomalacia
0.671 0.329 0.000
M82 Osteoporosis in diseases classified elsewhere
0.671 0.329 0.000
I07 Rheumatic tricuspid valve diseases
0.669 0.331 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.668 0.331 0.000
I08.0 Disorders of both mitral and aortic valves
0.669 0.331 0.000
Z04.8 Examination and observation for other specified reasons
0.668 0.332 0.000
Z13.1 Special screening examination for diabetes mellitus
0.668 0.332 0.000
R07.4 Chest pain, unspecified
0.667 0.333 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.667 0.333 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.667 0.333 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.667 0.333 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.667 0.333 0.000
T42.4 Benzodiazepines
0.667 0.333 0.000
J69 Pneumonitis due to solids and liquids
0.667 0.333 0.000
M79.5 Residual foreign body in soft tissue
0.666 0.334 0.000
C83.0 Small cell (diffuse)
0.665 0.335 0.000
R74 Abnormal serum enzyme levels
0.665 0.335 0.000
D68.6 Other Thrombophilia
0.664 0.336 0.000
D68.5 Primary Thrombophilia
0.664 0.336 0.000
D68.4 Acquired coagulation factor deficiency
0.664 0.336 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.664 0.336 0.000
D68.1 Hereditary factor XI deficiency
0.664 0.336 0.000
T51 Toxic effect of alcohol
0.664 0.336 0.000
A30-A49 Other bacterial diseases
0.663 0.337 0.000
I87.1 Compression of vein
0.663 0.337 0.000
S90 Superficial injury of ankle and foot
0.662 0.337 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.662 0.337 0.000
Z22.9 Carrier of infectious disease, unspecified
0.661 0.339 0.000
Z22.8 Carrier of other infectious diseases
0.661 0.339 0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection
0.661 0.339 0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission
0.661 0.339 0.000
Z22.2 Carrier of diphtheria
0.661 0.339 0.000
Z22.1 Carrier of other intestinal infectious diseases
0.661 0.339 0.000
Z22.0 Carrier of typhoid
0.661 0.339 0.000
Z52 Donors of organs and tissues
0.661 0.339 0.000
C71 Malignant neoplasm of brain
0.661 0.339 0.000
R46 Symptoms and signs involving appearance and behaviour
0.661 0.339 0.000
M35.0 Sicca syndrome [Sjogren]
0.661 0.339 0.000
M25.37 Other instability of joint (Ankle and foot)
0.660 0.340 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.659 0.341 0.000
J32.4 Chronic pansinusitis
0.659 0.341 0.000
I89.0 Lymphoedema, not elsewhere classified
0.659 0.341 0.000
C91 Lymphoid leukaemia
0.658 0.342 0.000
J39.8 Other specified diseases of upper respiratory tract
0.657 0.343 0.000
I84.6 Residual haemorrhoidal skin tags
0.657 0.343 0.000
Z54 Convalescence
0.657 0.343 0.000
Z44 Fitting and adjustment of external prosthetic device
0.657 0.343 0.000
S40 Superficial injury of shoulder and upper arm
0.657 0.343 0.000
A04.5 Campylobacter enteritis
0.657 0.343 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.656 0.344 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.655 0.345 0.000
C88 Malignant immunoproliferative diseases
0.654 0.346 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.654 0.346 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.654 0.346 0.000
M25.49 Effusion of joint (Site unspecified)
0.653 0.347 0.000
M25.48 Effusion of joint (Other)
0.653 0.347 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.653 0.347 0.000
M25.44 Effusion of joint (Hand)
0.653 0.347 0.000
M25.43 Effusion of joint (Forearm)
0.653 0.347 0.000
M25.42 Effusion of joint (Upper arm)
0.653 0.347 0.000
M25.41 Effusion of joint (Shoulder region)
0.653 0.347 0.000
M25.40 Effusion of joint (Multiple sites)
0.653 0.347 0.000
I77.1 Stricture of artery
0.653 0.347 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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