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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115447786
log Bayes Factor = 28.0188
Chromosome 6   position 34,354,073  (GRCh37) Explore rs115447786 on Ensembl!
Variant rs115447786 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
N40-N51 Diseases of male genital organs
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N40 Hyperplasia of prostate
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
I20 Angina pectoris
0.998 0.002 0.000
I77 Other disorders of arteries and arterioles
0.998 0.002 0.000
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.998 0.002 0.000
E78.0 Pure hypercholesterolaemia
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
I77.1 Stricture of artery
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.993 0.007 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.990 0.010 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.988 0.012 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.987 0.013 0.000
N80 Endometriosis
0.986 0.014 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.985 0.015 0.000
I21 Acute myocardial infarction
0.985 0.015 0.000
I20.9 Angina pectoris, unspecified
0.984 0.016 0.000
I25 Chronic ischaemic heart disease
0.984 0.016 0.000
N84 Polyp of female genital tract
0.979 0.021 0.000
E11 Non-insulin-dependent diabetes mellitus
0.979 0.021 0.000
I25.1 Atherosclerotic heart disease
0.978 0.022 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.978 0.022 0.000
E11.9 Without complications
0.975 0.025 0.000
I71 Aortic aneurysm and dissection
0.974 0.026 0.000
E21.0 Primary hyperparathyroidism
0.974 0.026 0.000
E83 Disorders of mineral metabolism
0.974 0.026 0.000
Chapter XXI Factors influencing health status and contact with health services
0.972 0.028 0.000
N84.1 Polyp of cervix uteri
0.972 0.028 0.000
N41 Inflammatory diseases of prostate
0.967 0.033 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.962 0.038 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.959 0.041 0.000
I21.9 Acute myocardial infarction, unspecified
0.959 0.041 0.000
N80.0 Endometriosis of uterus
0.958 0.042 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.955 0.045 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.953 0.047 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.949 0.051 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.949 0.051 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.948 0.052 0.000
E14 Unspecified diabetes mellitus
0.947 0.053 0.000
I22 Subsequent myocardial infarction
0.943 0.057 0.000
L82 Seborrhoeic keratosis
0.943 0.057 0.000
I20.0 Unstable angina
0.943 0.057 0.000
E00-E07 Disorders of thyroid gland
0.942 0.058 0.000
G57 Mononeuropathies of lower limb
0.938 0.062 0.000
Chapter V Mental and behavioural disorders
0.937 0.063 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.936 0.064 0.000
N50 Other disorders of male genital organs
0.933 0.067 0.000
E83.1 Disorders of iron metabolism
0.931 0.069 0.000
I77.6 Arteritis, unspecified
0.930 0.070 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.925 0.075 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.924 0.076 0.000
N80.8 Other endometriosis
0.923 0.077 0.000
E83.4 Disorders of magnesium metabolism
0.921 0.079 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.919 0.081 0.000
E14.9 Without complications
0.916 0.084 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.914 0.086 0.000
R00 Abnormalities of heart beat
0.912 0.088 0.000
I50 Heart failure
0.910 0.090 0.000
R87 Abnormal findings in specimens from female genital organs
0.909 0.091 0.000
N86 Erosion and ectropion of cervix uteri
0.908 0.092 0.000
E27 Other disorders of adrenal gland
0.905 0.095 0.000
Z73 Problems related to life-management difficulty
0.902 0.098 0.000
N41.1 Chronic prostatitis
0.901 0.099 0.000
I44 Atrioventricular and left bundle-branch block
0.901 0.099 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.898 0.102 0.000
R00.1 Bradycardia, unspecified
0.896 0.104 0.000
I05-I09 Chronic rheumatic heart diseases
0.896 0.104 0.000
I31 Other diseases of pericardium
0.896 0.104 0.000
G57.6 Lesion of plantar nerve
0.895 0.105 0.000
N20-N23 Urolithiasis
0.892 0.108 0.000
Chapter II Neoplasms
0.892 0.108 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.892 0.108 0.000
N50.8 Other specified disorders of male genital organs
0.891 0.109 0.000
N42 Other disorders of prostate
0.888 0.112 0.000
N41.0 Acute prostatitis
0.888 0.112 0.000
I24 Other acute ischaemic heart diseases
0.887 0.113 0.000
E05.9 Thyrotoxicosis, unspecified
0.885 0.115 0.000
Z73.3 Stress, not elsewhere classified
0.884 0.116 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.884 0.116 0.000
I45 Other conduction disorders
0.877 0.123 0.000
Z46 Fitting and adjustment of other devices
0.877 0.123 0.000
I50.0 Congestive heart failure
0.874 0.126 0.000
I34 Nonrheumatic mitral valve disorders
0.872 0.128 0.000
Z42 Follow-up care involving plastic surgery
0.870 0.130 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.870 0.130 0.000
C60-C63 Malignant neoplasms of male genital organs
0.867 0.133 0.000
G20-G26 Extrapyramidal and movement disorders
0.867 0.133 0.000
Z43 Attention to artificial openings
0.865 0.135 0.000
Chapter I Certain infectious and parasitic diseases
0.862 0.138 0.000
I44.7 Left bundle-branch block, unspecified
0.860 0.140 0.000
R87.6 Abnormal cytological findings
0.859 0.141 0.000
N80.9 Endometriosis, unspecified
0.859 0.141 0.000
I20.1 Angina pectoris with documented spasm
0.859 0.141 0.000
L91 Hypertrophic disorders of skin
0.857 0.143 0.000
I74 Arterial embolism and thrombosis
0.857 0.143 0.000
C61 Malignant neoplasm of prostate
0.855 0.145 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.854 0.146 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.850 0.150 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.849 0.151 0.000
I24.8 Other forms of acute ischaemic heart disease
0.848 0.152 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.846 0.154 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.844 0.156 0.000
Z51 Other medical care
0.842 0.158 0.000
Z48 Other surgical follow-up care
0.838 0.162 0.000
Z46.6 Fitting and adjustment of urinary device
0.838 0.162 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.835 0.165 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.829 0.171 0.000
N21 Calculus of lower urinary tract
0.828 0.172 0.000
F41 Other anxiety disorders
0.827 0.173 0.000
E21.3 Hyperparathyroidism, unspecified
0.827 0.173 0.000
I51 Complications and ill-defined descriptions of heart disease
0.822 0.178 0.000
F30-F39 Mood [affective] disorders
0.822 0.178 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.821 0.179 0.000
D10-D36 Benign neoplasms
0.816 0.184 0.000
R00.0 Tachycardia, unspecified
0.816 0.184 0.000
R86 Abnormal findings in specimens from male genital organs
0.814 0.186 0.000
L91.8 Other hypertrophic disorders of skin
0.814 0.186 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.814 0.186 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.812 0.188 0.000
N94.1 Dyspareunia
0.809 0.191 0.000
R27 Other lack of coordination
0.808 0.192 0.000
G25 Other extrapyramidal and movement disorders
0.805 0.195 0.000
R42 Dizziness and giddiness
0.804 0.196 0.000
R26 Abnormalities of gait and mobility
0.804 0.196 0.000
F41.9 Anxiety disorder, unspecified
0.802 0.198 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.801 0.199 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.800 0.200 0.000
N80.2 Endometriosis of Fallopian tube
0.800 0.200 0.000
N85.2 Hypertrophy of uterus
0.799 0.201 0.000
E11.2 With renal complications
0.799 0.201 0.000
I33 Acute and subacute endocarditis
0.799 0.201 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.798 0.202 0.000
I60-I69 Cerebrovascular diseases
0.798 0.202 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.795 0.205 0.000
I72 Other aneurysm
0.795 0.205 0.000
M45-M49 Spondylopathies
0.795 0.205 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.794 0.206 0.000
I77.8 Other specified disorders of arteries and arterioles
0.793 0.207 0.000
Chapter VIII Diseases of the ear and mastoid process
0.792 0.208 0.000
D27 Benign neoplasm of ovary
0.792 0.208 0.000
N10-N16 Renal tubulo-interstitial diseases
0.792 0.208 0.000
E78.4 Other hyperlipidaemia
0.791 0.209 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.791 0.209 0.000
I34.0 Mitral (valve) insufficiency
0.791 0.209 0.000
I30 Acute pericarditis
0.790 0.210 0.000
E22 Hyperfunction of pituitary gland
0.790 0.210 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.789 0.210 0.000
N94.6 Dysmenorrhoea, unspecified
0.788 0.212 0.000
L89 Decubitus ulcer
0.788 0.212 0.000
E24 Cushing's syndrome
0.785 0.215 0.000
Z48.8 Other specified surgical follow-up care
0.784 0.216 0.000
N42.1 Congestion and haemorrhage of prostate
0.783 0.217 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.783 0.217 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.781 0.219 0.000
N46 Male infertility
0.780 0.220 0.000
M20-M25 Other joint disorders
0.779 0.221 0.000
F80-F89 Disorders of psychological development
0.779 0.221 0.000
Z72 Problems related to lifestyle
0.776 0.224 0.000
I20.8 Other forms of angina pectoris
0.773 0.227 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.772 0.227 0.000
I05 Rheumatic mitral valve diseases
0.772 0.227 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.772 0.228 0.000
I31.9 Disease of pericardium, unspecified
0.771 0.229 0.000
N82 Fistulae involving female genital tract
0.771 0.229 0.000
N21.0 Calculus in bladder
0.770 0.230 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.770 0.230 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.770 0.230 0.000
I71.0 Dissection of aorta [any part]
0.766 0.234 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.766 0.234 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.764 0.236 0.000
R06 Abnormalities of breathing
0.764 0.236 0.000
D12.0 Caecum
0.762 0.238 0.000
Z95.0 Presence of cardiac pacemaker
0.762 0.238 0.000
Z95.1 Presence of aortocoronary bypass graft
0.758 0.242 0.000
E78.8 Other disorders of lipoprotein metabolism
0.758 0.242 0.000
F45 Somatoform disorders
0.757 0.243 0.000
A00-A09 Intestinal infectious diseases
0.757 0.243 0.000
E20 Hypoparathyroidism
0.756 0.244 0.000
N84.2 Polyp of vagina
0.755 0.245 0.000
N84.9 Polyp of female genital tract, unspecified
0.755 0.245 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.755 0.245 0.000
F33 Recurrent depressive disorder
0.754 0.246 0.000
I69 Sequelae of cerebrovascular disease
0.753 0.247 0.000
N99-N99 Other disorders of the genitourinary system
0.753 0.247 0.000
E29 Testicular dysfunction
0.752 0.247 0.000
D45 Polycythaemia vera
0.752 0.248 0.000
D12.2 Ascending colon
0.752 0.248 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.750 0.250 0.000
I38 Endocarditis, valve unspecified
0.750 0.250 0.000
I31.3 Pericardial effusion (noninflammatory)
0.749 0.251 0.000
Z51.0 Radiotherapy session
0.749 0.251 0.000
M40-M43 Deforming dorsopathies
0.749 0.251 0.000
F40 Phobic anxiety disorders
0.748 0.252 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.747 0.253 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.745 0.255 0.000
G57.5 Tarsal tunnel syndrome
0.745 0.255 0.000
N42.2 Atrophy of prostate
0.745 0.255 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.745 0.255 0.000
Z52 Donors of organs and tissues
0.744 0.255 0.000
N93 Other abnormal uterine and vaginal bleeding
0.744 0.256 0.000
I45.9 Conduction disorder, unspecified
0.744 0.256 0.000
N84.3 Polyp of vulva
0.743 0.257 0.000
E11.6 With other specified complications
0.743 0.257 0.000
I25.5 Ischaemic cardiomyopathy
0.742 0.258 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.742 0.258 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.742 0.258 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.741 0.259 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.740 0.259 0.000
D12.4 Descending colon
0.739 0.261 0.000
Z76 Persons encountering health services in other circumstances
0.738 0.262 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.738 0.262 0.000
N80.5 Endometriosis of intestine
0.737 0.262 0.000
L94 Other localised connective tissue disorders
0.736 0.264 0.000
E85 Amyloidosis
0.735 0.265 0.000
D60-D64 Aplastic and other anaemias
0.734 0.266 0.000
I08 Multiple valve diseases
0.732 0.267 0.000
N91 Absent, scanty and rare menstruation
0.732 0.268 0.000
I45.2 Bifascicular block
0.730 0.270 0.000
Z51.3 Blood transfusion without reported diagnosis
0.729 0.271 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.729 0.271 0.000
Z44 Fitting and adjustment of external prosthetic device
0.728 0.271 0.000
R47-R49 Symptoms and signs involving speech and voice
0.728 0.271 0.000
Z49 Care involving dialysis
0.728 0.272 0.000
N83.2 Other and unspecified ovarian cysts
0.728 0.272 0.000
N13 Obstructive and reflux uropathy
0.727 0.273 0.000
Z43.3 Attention to colostomy
0.727 0.273 0.000
E28 Ovarian dysfunction
0.725 0.275 0.000
E23 Hypofunction and other disorders of pituitary gland
0.724 0.276 0.000
B99-B99 Other infectious diseases
0.723 0.277 0.000
E11.1 With ketoacidosis
0.723 0.277 0.000
E27.1 Primary adrenocortical insufficiency
0.720 0.280 0.000
H90-H95 Other disorders of ear
0.719 0.281 0.000
I35 Nonrheumatic aortic valve disorders
0.719 0.281 0.000
M45 Ankylosing spondylitis
0.719 0.281 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.718 0.282 0.000
Z72.0 Tobacco use
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.717 0.283 0.000
N44 Torsion of testis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.716 0.284 0.000
I11 Hypertensive heart disease
0.716 0.284 0.000
I77.5 Necrosis of artery
0.716 0.284 0.000
I77.4 Coeliac artery compression syndrome
0.716 0.284 0.000
I77.3 Arterial fibromuscular dysplasia
0.716 0.284 0.000
I77.2 Rupture of artery
0.716 0.284 0.000
I77.0 Arteriovenous fistula, acquired
0.716 0.284 0.000
D47.1 Chronic myeloproliferative disease
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E34 Other endocrine disorders
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E31 Polyglandular dysfunction
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
I42 Cardiomyopathy
0.715 0.285 0.000
E78.6 Lipoprotein deficiency
0.715 0.285 0.000
E78.3 Hyperchylomicronaemia
0.715 0.285 0.000
E78.1 Pure hyperglyceridaemia
0.715 0.285 0.000
E03 Other hypothyroidism
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
N98 Complications associated with artificial fertilisation
0.714 0.286 0.000
N96 Habitual aborter
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
R05 Cough
0.714 0.286 0.000
R26.0 Ataxic gait
0.713 0.287 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
E27.2 Addisonian crisis
0.712 0.288 0.000
N85.4 Malposition of uterus
0.711 0.288 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.711 0.289 0.000
L81 Other disorders of pigmentation
0.710 0.289 0.000
E26 Hyperaldosteronism
0.710 0.290 0.000
N00-N08 Glomerular diseases
0.710 0.290 0.000
G52 Disorders of other cranial nerves
0.710 0.290 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.708 0.292 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.708 0.292 0.000
E21.4 Other specified disorders of parathyroid gland
0.708 0.292 0.000
E21.2 Other hyperparathyroidism
0.708 0.292 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.708 0.292 0.000
D12.3 Transverse colon
0.708 0.292 0.000
N80.6 Endometriosis in cutaneous scar
0.707 0.293 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.707 0.293 0.000
C51-C58 Malignant neoplasms of female genital organs
0.707 0.293 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.707 0.293 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.706 0.293 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.706 0.293 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.706 0.293 0.000
M60-M63 Disorders of muscles
0.706 0.294 0.000
I25.6 Silent myocardial ischaemia
0.705 0.294 0.000
I25.4 Coronary artery aneurysm
0.705 0.294 0.000
I25.3 Aneurysm of heart
0.705 0.294 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.705 0.294 0.000
A08 Viral and other specified intestinal infections
0.704 0.296 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.704 0.296 0.000
N84.8 Polyp of other parts of female genital tract
0.702 0.298 0.000
E11.8 With unspecified complications
0.702 0.298 0.000
E11.7 With multiple complications
0.702 0.298 0.000
E11.0 With coma
0.702 0.298 0.000
Z95.3 Presence of xenogenic heart valve
0.700 0.300 0.000
G81 Hemiplegia
0.700 0.300 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.698 0.301 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.698 0.301 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.698 0.301 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.698 0.301 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.698 0.302 0.000
E83.8 Other disorders of mineral metabolism
0.698 0.302 0.000
E83.2 Disorders of zinc metabolism
0.698 0.302 0.000
E83.0 Disorders of copper metabolism
0.698 0.302 0.000
D62 Acute posthaemorrhagic anaemia
0.698 0.302 0.000
E73 Lactose intolerance
0.698 0.302 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.698 0.302 0.000
I37 Pulmonary valve disorders
0.697 0.303 0.000
R87.9 Unspecified abnormal finding
0.697 0.303 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.697 0.303 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.696 0.304 0.000
N50.0 Atrophy of testis
0.694 0.306 0.000
M86-M90 Other osteopathies
0.693 0.307 0.000
N41.8 Other inflammatory diseases of prostate
0.693 0.307 0.000
N41.3 Prostatocystitis
0.693 0.307 0.000
N41.2 Abscess of prostate
0.693 0.307 0.000
R29.6 Tendency to fall, not elsewhere classified
0.693 0.307 0.000
N20 Calculus of kidney and ureter
0.693 0.307 0.000
E78.2 Mixed hyperlipidaemia
0.692 0.307 0.000
I15 Secondary hypertension
0.692 0.308 0.000
I61 Intracerebral haemorrhage
0.692 0.308 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.691 0.309 0.000
R86.9 Unspecified abnormal finding
0.691 0.309 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.691 0.309 0.000
R06.2 Wheezing
0.690 0.310 0.000
I70 Atherosclerosis
0.690 0.310 0.000
E27.8 Other specified disorders of adrenal gland
0.690 0.310 0.000
M31 Other necrotising vasculopathies
0.689 0.311 0.000
Z75 Problems related to medical facilities and other health care
0.688 0.312 0.000
L60-L75 Disorders of skin appendages
0.688 0.312 0.000
L93 Lupus erythematosus
0.688 0.312 0.000
I09 Other rheumatic heart diseases
0.688 0.312 0.000
I22.8 Subsequent myocardial infarction of other sites
0.687 0.313 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.687 0.313 0.000
R83 Abnormal findings in cerebrospinal fluid
0.687 0.313 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.687 0.313 0.000
R87.7 Abnormal histological findings
0.687 0.313 0.000
R02 Gangrene, not elsewhere classified
0.685 0.315 0.000
I45.3 Trifascicular block
0.684 0.316 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.684 0.316 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.684 0.316 0.000
G00 Bacterial meningitis, not elsewhere classified
0.684 0.316 0.000
L10-L14 Bullous disorders
0.683 0.317 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.682 0.318 0.000
R06.4 Hyperventilation
0.682 0.318 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.681 0.319 0.000
L87 Transepidermal elimination disorders
0.681 0.319 0.000
L88 Pyoderma gangrenosum
0.681 0.319 0.000
L86 Keratoderma in diseases classified elsewhere
0.681 0.319 0.000
L83 Acanthosis nigricans
0.681 0.319 0.000
L80 Vitiligo
0.681 0.319 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.680 0.320 0.000
I51.9 Heart disease, unspecified
0.680 0.320 0.000
D30 Benign neoplasm of urinary organs
0.679 0.321 0.000
E14.8 With unspecified complications
0.679 0.321 0.000
E14.7 With multiple complications
0.679 0.321 0.000
E14.6 With other specified complications
0.679 0.321 0.000
E14.5 With peripheral circulatory complications
0.679 0.321 0.000
E14.4 With neurological complications
0.679 0.321 0.000
E14.2 Withrenal complications
0.679 0.321 0.000
E14.1 With ketoacidosis
0.679 0.321 0.000
E14.0 With coma
0.679 0.321 0.000
Z43.2 Attention to ileostomy
0.678 0.322 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
E50-E64 Other nutritional deficiencies
0.678 0.322 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.677 0.323 0.000
F32 Depressive episode
0.677 0.323 0.000
Z95.4 Presence of other heart-valve replacement
0.676 0.324 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.676 0.324 0.000
E00 Congenital iodine-deficiency syndrome
0.676 0.324 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.676 0.324 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.675 0.325 0.000
M25 Other joint disorders, not elsewhere classified
0.675 0.325 0.000
G90-G99 Other disorders of the nervous system
0.675 0.325 0.000
Chapter VII Diseases of the eye and adnexa
0.674 0.326 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.674 0.326 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.672 0.328 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.672 0.328 0.000
G57.4 Lesion of medial popliteal nerve
0.672 0.328 0.000
G57.3 Lesion of lateral popliteal nerve
0.672 0.328 0.000
G57.2 Lesion of femoral nerve
0.672 0.328 0.000
G57.1 Meralgia paraesthetica
0.672 0.328 0.000
G57.0 Lesion of sciatic nerve
0.672 0.328 0.000
M21 Other acquired deformities of limbs
0.672 0.328 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.672 0.328 0.000
F70-F79 Mental retardation
0.672 0.328 0.000
M91-M94 Chondropathies
0.672 0.328 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.671 0.329 0.000
I05.9 Mitral valve disease, unspecified
0.671 0.329 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.669 0.331 0.000
I72.3 Aneurysm of iliac artery
0.669 0.331 0.000
N50.9 Disorder of male genital organs, unspecified
0.669 0.331 0.000
I44.1 Atrioventricular block, second degree
0.669 0.331 0.000
G25.0 Essential tremor
0.669 0.331 0.000
G54 Nerve root and plexus disorders
0.668 0.332 0.000
M05-M14 Inflammatory polyarthropathies
0.668 0.332 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.667 0.333 0.000
N94.4 Primary dysmenorrhoea
0.667 0.333 0.000
A30-A49 Other bacterial diseases
0.666 0.334 0.000
Z41 Procedures for purposes other than remedying health state
0.666 0.334 0.000
I21.4 Acute subendocardial myocardial infarction
0.666 0.334 0.000
D18 Haemangioma and lymphangioma, any site
0.665 0.335 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.664 0.335 0.000
I45.6 Preexcitation syndrome
0.664 0.336 0.000
I45.5 Other specified heart block
0.663 0.337 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.663 0.337 0.000
E05.8 Other thyrotoxicosis
0.662 0.338 0.000
E05.5 Thyroid crisis or storm
0.662 0.338 0.000
E05.4 Thyrotoxicosis factitia
0.662 0.338 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.662 0.338 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.662 0.338 0.000
E27.9 Disorder of adrenal gland, unspecified
0.662 0.338 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.662 0.338 0.000
I36 Nonrheumatic tricuspid valve disorders
0.661 0.338 0.000
G03 Meningitis due to other and unspecified causes
0.661 0.338 0.000
C54 Malignant neoplasm of corpus uteri
0.661 0.339 0.000
D47.4 Osteomyelofibrosis
0.661 0.339 0.000
I44.2 Atrioventricular block, complete
0.661 0.339 0.000
E14.3 With ophthalmic complications
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
R29.4 Clicking hip
0.659 0.341 0.000
R29.3 Abnormal posture
0.659 0.341 0.000
R29.2 Abnormal reflex
0.659 0.341 0.000
R29.1 Meningismus
0.659 0.341 0.000
R29.0 Tetany
0.659 0.341 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.659 0.341 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.659 0.341 0.000
G11 Hereditary ataxia
0.658 0.341 0.000
I25.2 Old myocardial infarction
0.658 0.342 0.000
R03.1 Nonspecific low blood-pressure reading
0.658 0.342 0.000
I45.8 Other specified conduction disorders
0.658 0.342 0.000
Z43.8 Attention to other artificial openings
0.658 0.342 0.000
D35.1 Parathyroid gland
0.657 0.343 0.000
I33.0 Acute and subacute infective endocarditis
0.657 0.343 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.657 0.343 0.000
N43 Hydrocele and spermatocele
0.656 0.344 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.656 0.344 0.000
N94.5 Secondary dysmenorrhoea
0.656 0.344 0.000
N94.2 Vaginismus
0.656 0.344 0.000
N94.0 Mittelschmerz
0.656 0.344 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.655 0.345 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.655 0.345 0.000
M24 Other specific joint derangements
0.654 0.346 0.000
M00-M03 Infectious arthropathies
0.653 0.347 0.000
C79 Secondary malignant neoplasm of other sites
0.653 0.347 0.000
M47 Spondylosis
0.653 0.347 0.000
M41 Scoliosis
0.652 0.348 0.000
N42.9 Disorder of prostate, unspecified
0.652 0.348 0.000
R87.8 Other abnormal findings
0.652 0.348 0.000
R87.5 Abnormal microbiological findings
0.652 0.348 0.000
R87.4 Abnormal immunological findings
0.652 0.348 0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.652 0.348 0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.652 0.348 0.000
R87.1 Abnormal level of hormones
0.652 0.348 0.000
R87.0 Abnormal level of enzymes
0.652 0.348 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.651 0.349 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.650 0.350 0.000
R27.0 Ataxia, unspecified
0.649 0.351 0.000
E27.5 Adrenomedullary hyperfunction
0.649 0.351 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.649 0.351 0.000
E27.0 Other adrenocortical overactivity
0.649 0.351 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.648 0.352 0.000
Z43.5 Attention to cyctostomy
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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