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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115631386
log Bayes Factor = 14.487
Chromosome 5   position 2,714,838  (GRCh37) Explore rs115631386 on Ensembl!
Variant rs115631386 is part of Cluster X0024

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
I84 Haemorrhoids
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
I84.9 Unspecified haemorrhoids without complication
0.993 0.007 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.992 0.008 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.991 0.009 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
R69 Unknown and unspecified causes of morbidity
0.987 0.013 0.000
I84.8 Unspecified haemorrhoids with other complications
0.987 0.013 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.985 0.015 0.000
R50 Fever of unknown origin
0.984 0.016 0.000
Chapter VII Diseases of the eye and adnexa
0.981 0.019 0.000
L03 Cellulitis
0.981 0.019 0.000
R50.9 Fever, unspecified
0.975 0.025 0.000
H40-H42 Glaucoma
0.958 0.042 0.000
M50-M54 Other dorsopathies
0.957 0.043 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.956 0.044 0.000
I30-I52 Other forms of heart disease
0.953 0.047 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.949 0.051 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.942 0.058 0.000
H40 Glaucoma
0.941 0.059 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.938 0.062 0.000
L03.1 Cellulitis of other parts of limb
0.938 0.062 0.000
H40.9 Glaucoma, unspecified
0.936 0.064 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.933 0.067 0.000
A30-A49 Other bacterial diseases
0.922 0.078 0.000
B35-B49 Mycoses
0.921 0.079 0.000
M45-M49 Spondylopathies
0.915 0.085 0.000
M54 Dorsalgia
0.914 0.086 0.000
Chapter II Neoplasms
0.912 0.088 0.000
B25-B34 Other viral diseases
0.908 0.092 0.000
R52 Pain, not elsewhere classified
0.907 0.093 0.000
M80-M85 Disorders of bone density and structure
0.904 0.096 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.903 0.097 0.000
I84.2 Internal haemorrhoids without complication
0.901 0.099 0.000
O70 Perineal laceration during delivery
0.896 0.104 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.895 0.105 0.000
I82 Other venous embolism and thrombosis
0.888 0.112 0.000
I47 Paroxysmal tachycardia
0.886 0.114 0.000
O00-O08 Pregnancy with abortive outcome
0.884 0.116 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.883 0.117 0.000
L03.3 Cellulitis of trunk
0.882 0.118 0.000
H10-H13 Disorders of conjunctiva
0.882 0.118 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.877 0.122 0.000
R47-R49 Symptoms and signs involving speech and voice
0.877 0.123 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.876 0.124 0.000
D60-D64 Aplastic and other anaemias
0.874 0.126 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.873 0.127 0.000
R51 Headache
0.873 0.127 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.871 0.129 0.000
D00-D09 In situ neoplasms
0.868 0.132 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.868 0.132 0.000
M47 Spondylosis
0.863 0.137 0.000
O70.1 Second degree perineal laceration during delivery
0.860 0.140 0.000
R61 Hyperhidrosis
0.858 0.142 0.000
O42 Premature rupture of membranes
0.856 0.144 0.000
I34 Nonrheumatic mitral valve disorders
0.850 0.149 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.850 0.150 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.849 0.151 0.000
D80-D89 Certain disorders involving the immune mechanism
0.848 0.151 0.000
B34 Viral infection of unspecified site
0.844 0.156 0.000
L03.0 Cellulitis of finger and toe
0.842 0.158 0.000
I81 Portal vein thrombosis
0.837 0.163 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.835 0.165 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.835 0.165 0.000
M20-M25 Other joint disorders
0.834 0.166 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.832 0.168 0.000
O62 Abnormalities of forces of labour
0.831 0.169 0.000
D05 Carcinoma in situ of breast
0.829 0.171 0.000
I47.1 Supraventricular tachycardia
0.826 0.174 0.000
O47 False labour
0.826 0.174 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.824 0.176 0.000
A41 Other septicaemia
0.824 0.176 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
M54.9 Dorsalgia, unspecified
0.817 0.183 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.815 0.185 0.000
B37 Candidiasis
0.815 0.185 0.000
M47.8 Other spondylosis
0.813 0.187 0.000
H11 Other disorders of conjunctiva
0.810 0.190 0.000
I82.8 Embolism and thrombosis of other specified veins
0.807 0.193 0.000
R59 Enlarged lymph nodes
0.807 0.193 0.000
O48 Prolonged pregnancy
0.802 0.198 0.000
I33 Acute and subacute endocarditis
0.800 0.200 0.000
B07 Viral warts
0.800 0.200 0.000
I05-I09 Chronic rheumatic heart diseases
0.799 0.201 0.000
B34.9 Viral infection, unspecified
0.798 0.202 0.000
R52.1 Chronic intractable pain
0.795 0.205 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.795 0.205 0.000
S60-S69 Injuries to the wrist and hand
0.794 0.206 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.794 0.206 0.000
B15-B19 Viral hepatitis
0.794 0.206 0.000
L50-L54 Urticaria and erythema
0.794 0.206 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.792 0.208 0.000
I42 Cardiomyopathy
0.792 0.208 0.000
D64 Other anaemias
0.791 0.209 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.787 0.213 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.786 0.214 0.000
L82 Seborrhoeic keratosis
0.785 0.215 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.781 0.219 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.780 0.220 0.000
M54.5 Low back pain
0.780 0.220 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.779 0.221 0.000
I27 Other pulmonary heart diseases
0.779 0.221 0.000
D86 Sarcoidosis
0.779 0.221 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.779 0.221 0.000
R50.0 Fever with chills
0.778 0.222 0.000
O41 Other disorders of amniotic fluid and membranes
0.778 0.222 0.000
M81 Osteoporosis without pathological fracture
0.778 0.222 0.000
Chapter XX External causes of morbidity and mortality
0.776 0.224 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.776 0.224 0.000
I84.6 Residual haemorrhoidal skin tags
0.775 0.225 0.000
B95-B98 Bacterial, viral and other infectious agents
0.774 0.226 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.772 0.228 0.000
I34.0 Mitral (valve) insufficiency
0.772 0.228 0.000
M51 Other intervertebral disk disorders
0.770 0.230 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
O64.1 Obstructed labour due to breech presentation
0.767 0.233 0.000
M05-M14 Inflammatory polyarthropathies
0.767 0.233 0.000
O63 Long labour
0.766 0.234 0.000
I85 Oesophageal varices
0.764 0.236 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.764 0.236 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.763 0.237 0.000
B49 Unspecified mycosis
0.762 0.238 0.000
R61.9 Hyperhidrosis, unspecified
0.761 0.239 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.761 0.239 0.000
O04 Medical abortion
0.759 0.241 0.000
I84.3 External thrombosed haemorrhoids
0.757 0.243 0.000
I84.4 External haemorrhoids with other complications
0.757 0.243 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.757 0.243 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.756 0.244 0.000
T66-T78 Other and unspecified effects of external causes
0.755 0.245 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.753 0.247 0.000
I84.1 Internal haemorrhoids with other complications
0.751 0.249 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.751 0.249 0.000
I44 Atrioventricular and left bundle-branch block
0.749 0.251 0.000
R49 Voice disturbances
0.748 0.252 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.746 0.254 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.746 0.254 0.000
R60 Oedema, not elsewhere classified
0.746 0.254 0.000
R52.2 Other chronic pain
0.746 0.254 0.000
O30 Multiple gestation
0.745 0.255 0.000
L03.9 Cellulitis, unspecified
0.745 0.255 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.741 0.258 0.000
M85 Other disorders of bone density and structure
0.741 0.259 0.000
H55-H59 Other disorders of eye and adnexa
0.741 0.259 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.740 0.260 0.000
A46 Erysipelas
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.736 0.264 0.000
R54 Senility
0.736 0.264 0.000
O02 Other abnormal products of conception
0.734 0.266 0.000
D64.9 Anaemia, unspecified
0.732 0.268 0.000
L90 Atrophic disorders of skin
0.731 0.269 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.727 0.273 0.000
L40-L45 Papulosquamous disorders
0.726 0.274 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.723 0.277 0.000
L20-L30 Dermatitis and eczema
0.722 0.278 0.000
A41.9 Septicaemia, unspecified
0.721 0.279 0.000
A49 Bacterial infection of unspecified site
0.720 0.280 0.000
I30 Acute pericarditis
0.720 0.280 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.720 0.280 0.000
R47 Speech disturbances, not elsewhere classified
0.720 0.280 0.000
M54.3 Sciatica
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I88 Nonspecific lymphadenitis
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.717 0.283 0.000
O73 Retained placenta and membranes, without haemorrhage
0.717 0.283 0.000
O71 Other obstetric trauma
0.717 0.283 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.717 0.283 0.000
O66 Other obstructed labour
0.717 0.283 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.717 0.283 0.000
O61 Failed induction of labour
0.717 0.283 0.000
O60 Preterm delivery
0.717 0.283 0.000
I84.0 Internal thrombosed haemorrhoids
0.717 0.283 0.000
I89.0 Lymphoedema, not elsewhere classified
0.717 0.283 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.716 0.284 0.000
H00 Hordeolum and chalazion
0.716 0.284 0.000
O80-O84 Delivery
0.715 0.285 0.000
H11.3 Conjunctival haemorrhage
0.715 0.285 0.000
I86 Varicose veins of other sites
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
M24 Other specific joint derangements
0.715 0.285 0.000
L10-L14 Bullous disorders
0.713 0.286 0.000
M91-M94 Chondropathies
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.713 0.287 0.000
R68 Other general symptoms and signs
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R57 Shock, not elsewhere classified
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
M40-M43 Deforming dorsopathies
0.712 0.288 0.000
S00-S09 Injuries to the head
0.712 0.288 0.000
M50 Cervical disk disorders
0.712 0.288 0.000
B37.8 Candidiasis of other sites
0.712 0.288 0.000
L03.8 Cellulitis of other sites
0.712 0.288 0.000
R21 Rash and other nonspecific skin eruption
0.712 0.288 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.712 0.288 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.711 0.289 0.000
L04 Acute lymphadenitis
0.710 0.289 0.000
L01 Impetigo
0.710 0.289 0.000
L00 Staphylococcal scalded skin syndrome
0.710 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
O42.9 Premature rupture of membranes, unspecified
0.710 0.290 0.000
I87 Other disorders of veins
0.710 0.290 0.000
O62.2 Other uterine inertia
0.709 0.291 0.000
O32.1 Maternal care for breech presentation
0.709 0.291 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.708 0.292 0.000
O45 Premature separation of placenta [abruptio placentae]
0.707 0.293 0.000
O44 Placenta praevia
0.707 0.293 0.000
O43 Placental disorders
0.707 0.293 0.000
O33 Maternal care for known or suspected disproportion
0.707 0.293 0.000
O31 Complications specific to multiple gestation
0.707 0.293 0.000
O40 Polyhydramnios
0.707 0.293 0.000
I27.2 Other secondary pulmonary hypertension
0.706 0.294 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.706 0.294 0.000
R50.8 Other specified fever
0.706 0.294 0.000
R50.2 Drug-induced fever
0.706 0.294 0.000
R50.1 Persistent fever
0.706 0.294 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.705 0.295 0.000
M47.89 Other spondylosis (Site unspecified)
0.705 0.295 0.000
B35 Dermatophytosis
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.703 0.297 0.000
R23 Other skin changes
0.703 0.297 0.000
M23 Internal derangement of knee
0.703 0.297 0.000
M54.56 Low back pain (Lumbar region)
0.701 0.299 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.700 0.300 0.000
H43-H45 Disorders of vitreous body and globe
0.699 0.301 0.000
I49 Other cardiac arrhythmias
0.698 0.302 0.000
I31 Other diseases of pericardium
0.696 0.304 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.694 0.305 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.693 0.307 0.000
D86.9 Sarcoidosis, unspecified
0.693 0.307 0.000
C15-C26 Malignant neoplasms of digestive organs
0.693 0.307 0.000
I50 Heart failure
0.692 0.308 0.000
I33.0 Acute and subacute infective endocarditis
0.691 0.309 0.000
M54.2 Cervicalgia
0.691 0.309 0.000
M81.9 Osteoporosis, unspecified
0.687 0.313 0.000
H42 Glaucoma in diseases classified elsewhere
0.687 0.313 0.000
M54.6 Pain in thoracic spine
0.686 0.314 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
M53 Other dorsopathies, not elsewhere classified
0.686 0.314 0.000
H11.0 Pterygium
0.686 0.314 0.000
D55-D59 Haemolytic anaemias
0.686 0.314 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.685 0.315 0.000
M80 Osteoporosis with pathological fracture
0.683 0.317 0.000
I52 Other heart disorders in diseases classified elsewhere
0.683 0.317 0.000
I48 Atrial fibrillation and flutter
0.683 0.317 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.683 0.317 0.000
I41 Myocarditis in diseases classified elsewhere
0.683 0.317 0.000
I40 Acute myocarditis
0.683 0.317 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.683 0.317 0.000
I37 Pulmonary valve disorders
0.683 0.317 0.000
I36 Nonrheumatic tricuspid valve disorders
0.683 0.317 0.000
I32 Pericarditis in diseases classified elsewhere
0.683 0.317 0.000
O20 Haemorrhage in early pregnancy
0.683 0.317 0.000
I26 Pulmonary embolism
0.682 0.318 0.000
I47.2 Ventricular tachycardia
0.682 0.318 0.000
O75.8 Other specified complications of labour and delivery
0.681 0.319 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.680 0.320 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.680 0.320 0.000
O64.5 Obstructed labour due to compound presentation
0.680 0.320 0.000
O64.4 Obstructed labour due to shoulder presentation
0.680 0.320 0.000
O64.3 Obstructed labour due to brow presentation
0.680 0.320 0.000
O64.2 Obstructed labour due to face presentation
0.680 0.320 0.000
L03.2 Cellulitis of face
0.680 0.320 0.000
R52.9 Pain, unspecified
0.679 0.321 0.000
D03 Melanoma in situ
0.679 0.321 0.000
L85 Other epidermal thickening
0.678 0.322 0.000
D61 Other aplastic anaemias
0.676 0.323 0.000
H40.8 Other glaucoma
0.675 0.325 0.000
H40.6 Glaucoma secondary to drugs
0.675 0.325 0.000
H40.5 Glaucoma secondary to other eye disorders
0.675 0.325 0.000
H40.4 Glaucoma secondary to eye inflammation
0.675 0.325 0.000
H40.3 Glaucoma secondary to eye trauma
0.675 0.325 0.000
D62 Acute posthaemorrhagic anaemia
0.673 0.327 0.000
H02 Other disorders of eyelid
0.673 0.327 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.672 0.328 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.672 0.328 0.000
D45 Polycythaemia vera
0.672 0.328 0.000
M70-M79 Other soft tissue disorders
0.672 0.328 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.672 0.328 0.000
C92 Myeloid leukaemia
0.671 0.329 0.000
O04.9 Complete or unspecified, without complication
0.670 0.330 0.000
T33-T35 Frostbite
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.669 0.331 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.669 0.331 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.669 0.331 0.000
T00-T07 Injuries involving multiple body regions
0.669 0.331 0.000
S10-S19 Injuries to the neck
0.669 0.331 0.000
O24 Diabetes mellitus in pregnancy
0.669 0.331 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.668 0.332 0.000
H30-H36 Disorders of choroid and retina
0.667 0.332 0.000
S64 Injury of nerves at wrist and hand level
0.667 0.333 0.000
I38 Endocarditis, valve unspecified
0.667 0.333 0.000
M47.2 Other spondylosis with radiculopathy
0.666 0.334 0.000
M84 Disorders of continuity of bone
0.666 0.334 0.000
M54.1 Radiculopathy
0.666 0.334 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.665 0.335 0.000
M45 Ankylosing spondylitis
0.665 0.335 0.000
M25 Other joint disorders, not elsewhere classified
0.664 0.336 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.663 0.336 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.663 0.337 0.000
A48 Other bacterial diseases, not elsewhere classified
0.661 0.339 0.000
A44 Bartonellosis
0.661 0.339 0.000
A43 Nocardiosis
0.661 0.339 0.000
A42 Actinomycosis
0.661 0.339 0.000
A40 Streptococcal septicaemia
0.661 0.339 0.000
A39 Meningococcal infection
0.661 0.339 0.000
A37 Whooping cough
0.661 0.339 0.000
A36 Diphtheria
0.661 0.339 0.000
A32 Listeriosis
0.661 0.339 0.000
A31 Infection due to other mycobacteria
0.661 0.339 0.000
A30 Leprosy [Hansen's disease]
0.661 0.339 0.000
A38 Scarlet fever
0.661 0.339 0.000
A35 Other tetanus
0.661 0.339 0.000
A34 Obstetrical tetanus
0.661 0.339 0.000
A33 Tetanus neonatorum
0.661 0.339 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.661 0.339 0.000
B48 Other mycoses, not elsewhere classified
0.661 0.339 0.000
B47 Mycetoma
0.661 0.339 0.000
B46 Zygomycosis
0.661 0.339 0.000
B45 Cryptococcosis
0.661 0.339 0.000
B44 Aspergillosis
0.661 0.339 0.000
B43 Chromomycosis and phaeomycotic abscess
0.661 0.339 0.000
B42 Sporotrichosis
0.661 0.339 0.000
B41 Paracoccidioidomycosis
0.661 0.339 0.000
B40 Blastomycosis
0.661 0.339 0.000
B39 Histoplasmosis
0.661 0.339 0.000
B38 Coccidioidomycosis
0.661 0.339 0.000
B36 Other superficial mycoses
0.661 0.339 0.000
R55 Syncope and collapse
0.660 0.340 0.000
L53 Other erythematous conditions
0.659 0.341 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.657 0.343 0.000
B37.0 Candidal stomatitis
0.657 0.343 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.656 0.344 0.000
M49 Spondylopathies in diseases classified elsewhere
0.656 0.344 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.656 0.344 0.000
R49.0 Dysphonia
0.656 0.344 0.000
I44.1 Atrioventricular block, second degree
0.656 0.344 0.000
M54.8 Other dorsalgia
0.655 0.345 0.000
M54.0 Panniculitis affecting regions of neck and back
0.655 0.345 0.000
D04 Carcinoma in situ of skin
0.655 0.345 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.654 0.346 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.654 0.346 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.654 0.346 0.000
C51-C58 Malignant neoplasms of female genital organs
0.653 0.347 0.000
T79-T79 Certain early complications of trauma
0.653 0.347 0.000
B33 Other viral diseases, not elsewhere classified
0.651 0.349 0.000
B30 Viral conjunctivitis
0.651 0.349 0.000
B27 Infectious mononucleosis
0.651 0.349 0.000
B26 Mumps
0.651 0.349 0.000
B25 Cytomegaloviral disease
0.651 0.349 0.000
L08 Other local infections of skin and subcutaneous tissue
0.650 0.350 0.000
R52.0 Acute pain
0.650 0.350 0.000
C81 Hodgkin's disease
0.650 0.350 0.000
M83 Adult osteomalacia
0.648 0.352 0.000
M82 Osteoporosis in diseases classified elsewhere
0.648 0.352 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.648 0.352 0.000
B18 Chronic viral hepatitis
0.648 0.352 0.000
I44.6 Other and unspecified fascicular block
0.647 0.353 0.000
H40.2 Primary angle-closure glaucoma
0.647 0.353 0.000
L90.0 Lichen sclerosus et atrophicus
0.647 0.353 0.000
M48 Other spondylopathies
0.647 0.353 0.000
D86.1 Sarcoidosis of lymph nodes
0.645 0.355 0.000
O36 Maternal care for other known or suspected foetal problems
0.645 0.355 0.000
H01 Other inflammation of eyelid
0.644 0.355 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.643 0.357 0.000
I08 Multiple valve diseases
0.643 0.357 0.000
O70.9 Perineal laceration during delivery, unspecified
0.643 0.357 0.000
O70.3 Fourth degree perineal laceration during delivery
0.643 0.357 0.000
D05.0 Lobular carcinoma in situ
0.642 0.357 0.000
S70-S79 Injuries to the hip and thigh
0.642 0.357 0.000
O47.9 False labour, unspecified
0.642 0.358 0.000
O70.2 Third degree perineal laceration during delivery
0.641 0.359 0.000
I42.9 Cardiomyopathy, unspecified
0.641 0.359 0.000
R60.9 Oedema, unspecified
0.640 0.360 0.000
O72 Postpartum haemorrhage
0.639 0.361 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.638 0.362 0.000
C60-C63 Malignant neoplasms of male genital organs
0.637 0.363 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.636 0.363 0.000
I82.3 Embolism and thrombosis of renal vein
0.636 0.363 0.000
I82.2 Embolism and thrombosis of vena cava
0.636 0.363 0.000
I82.1 Thrombophlebitis migrans
0.636 0.363 0.000
I82.0 Budd-Chiari syndrome
0.636 0.363 0.000
M46 Other inflammatory spondylopathies
0.636 0.364 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.635 0.365 0.000
I47.0 Reentry ventricular arrhythmia
0.635 0.365 0.000
R59.0 Localised enlarged lymph nodes
0.635 0.365 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.635 0.365 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.634 0.366 0.000
O07 Failed attempted abortion
0.634 0.366 0.000
O06 Unspecified abortion
0.634 0.366 0.000
O05 Other abortion
0.634 0.366 0.000
O01 Hydatidiform mole
0.634 0.366 0.000
O00 Ectopic pregnancy
0.634 0.366 0.000
O47.0 False labour before 37 completed weeks of gestation
0.634 0.366 0.000
I28 Other diseases of pulmonary vessels
0.633 0.367 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.633 0.367 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.633 0.367 0.000
S80-S89 Injuries to the knee and lower leg
0.633 0.367 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.632 0.368 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.632 0.368 0.000
H10 Conjunctivitis
0.632 0.368 0.000
M47.9 Spondylosis, unspecified
0.632 0.368 0.000
L89 Decubitus ulcer
0.632 0.368 0.000
D05.1 Intraductal carcinoma in situ
0.631 0.369 0.000
O41.0 Oligohydramnios
0.629 0.371 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.629 0.371 0.000
B06 Rubella [German measles]
0.629 0.371 0.000
B05 Measles
0.629 0.371 0.000
B01 Varicella [chickenpox]
0.629 0.371 0.000
B00 Herpesviral [herpes simplex] infections
0.629 0.371 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.629 0.371 0.000
B04 Monkeypox
0.629 0.371 0.000
B03 Smallpox
0.629 0.371 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.629 0.371 0.000
I95 Hypotension
0.628 0.372 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.628 0.372 0.000
O97 Death from sequelae of direct obstetric causes
0.628 0.372 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.628 0.372 0.000
O95 Obstetric death of unspecified cause
0.628 0.372 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.628 0.372 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.628 0.372 0.000
O02.1 Missed abortion
0.627 0.373 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.627 0.373 0.000
I45 Other conduction disorders
0.627 0.373 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.626 0.374 0.000
M54.4 Lumbago with sciatica
0.626 0.374 0.000
O75.9 Complication of labour and delivery, unspecified
0.626 0.374 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.626 0.374 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.626 0.374 0.000
O75.4 Other complications of obstetric surgery and procedures
0.626 0.374 0.000
O75.3 Other infection during labour
0.626 0.374 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.626 0.374 0.000
O75.1 Shock during or following labour and delivery
0.626 0.374 0.000
O75.0 Maternal distress during labour and delivery
0.626 0.374 0.000
M34 Systemic sclerosis
0.626 0.374 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.625 0.375 0.000
I34.1 Mitral (valve) prolapse
0.625 0.375 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.625 0.375 0.000
B91 Sequelae of poliomyelitis
0.624 0.376 0.000
M85.8 Other specified disorders of bone density and structure
0.624 0.376 0.000
D09 Carcinoma in situ of other and unspecified sites
0.622 0.377 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.622 0.377 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.622 0.377 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.622 0.377 0.000
O29 Complications of anaesthesia during pregnancy
0.622 0.378 0.000
O28 Abnormal findings on antenatal screening of mother
0.622 0.378 0.000
O23 Infections of genito-urinary tract in pregnancy
0.622 0.378 0.000
O22 Venous complications in pregnancy
0.622 0.378 0.000
O21 Excessive vomiting in pregnancy
0.622 0.378 0.000
O25 Malnutrition in pregnancy
0.622 0.378 0.000
D70 Agranulocytosis
0.622 0.378 0.000
I05 Rheumatic mitral valve diseases
0.621 0.379 0.000
T51 Toxic effect of alcohol
0.620 0.380 0.000
Chapter VI Diseases of the nervous system
0.620 0.380 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.619 0.381 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.619 0.381 0.000
M47.1 Other spondylosis with myelopathy
0.619 0.381 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.619 0.381 0.000
T68 Hypothermia
0.618 0.382 0.000
M22 Disorders of patella
0.618 0.382 0.000
S50-S59 Injuries to the elbow and forearm
0.617 0.382 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.617 0.383 0.000
M21 Other acquired deformities of limbs
0.617 0.383 0.000
I49.1 Atrial premature depolarisation
0.616 0.384 0.000
R61.1 Generalised hyperhidrosis
0.615 0.384 0.000
R61.0 Localised hyperhidrosis
0.615 0.384 0.000
C91 Lymphoid leukaemia
0.615 0.385 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.614 0.386 0.000
M47.82 Other spondylosis (Cervical region)
0.614 0.386 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.613 0.386 0.000
L05 Pilonidal cyst
0.613 0.386 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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