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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115811434
log Bayes Factor = 12.939
Chromosome 4   position 82,956,773  (GRCh37) Explore rs115811434 on Ensembl!
Variant rs115811434 is part of Cluster X0089

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
N10-N16 Renal tubulo-interstitial diseases
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.993 0.007 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
N30-N39 Other diseases of urinary system
0.991 0.009 0.000
N13 Obstructive and reflux uropathy
0.991 0.009 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
N30 Cystitis
0.971 0.029 0.000
C50-C50 Malignant neoplasm of breast
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.965 0.035 0.000
M50-M54 Other dorsopathies
0.962 0.038 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.956 0.044 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.954 0.046 0.000
D00-D09 In situ neoplasms
0.954 0.046 0.000
M70-M79 Other soft tissue disorders
0.951 0.049 0.000
M54 Dorsalgia
0.948 0.052 0.000
C50 Malignant neoplasm of breast
0.946 0.054 0.000
N39 Other disorders of urinary system
0.941 0.059 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.940 0.060 0.000
N13.3 Other and unspecified hydronephrosis
0.937 0.063 0.000
C77.3 Axillary and upper limb lymph nodes
0.937 0.063 0.000
N20-N23 Urolithiasis
0.933 0.067 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.932 0.068 0.000
M79.6 Pain in limb
0.931 0.069 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.930 0.070 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.926 0.074 0.000
L60-L75 Disorders of skin appendages
0.924 0.076 0.000
S00-S09 Injuries to the head
0.923 0.077 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.921 0.079 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.919 0.081 0.000
N30.9 Cystitis, unspecified
0.917 0.083 0.000
M54.5 Low back pain
0.909 0.091 0.000
C79 Secondary malignant neoplasm of other sites
0.904 0.096 0.000
Z36 Antenatal screening
0.903 0.097 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.902 0.098 0.000
C77.1 Intrathoracic lymph nodes
0.899 0.101 0.000
N39.3 Stress incontinence
0.896 0.104 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.894 0.106 0.000
F41 Other anxiety disorders
0.889 0.111 0.000
N39.8 Other specified disorders of urinary system
0.888 0.112 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.886 0.114 0.000
C50.9 Breast, unspecified
0.882 0.118 0.000
D05 Carcinoma in situ of breast
0.882 0.118 0.000
S60-S69 Injuries to the wrist and hand
0.879 0.121 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.879 0.121 0.000
N17-N19 Renal failure
0.878 0.122 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.877 0.123 0.000
L71 Rosacea
0.873 0.127 0.000
N30.8 Other cystitis
0.872 0.128 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.872 0.128 0.000
Z60 Problems related to social environment
0.868 0.132 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.867 0.133 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.859 0.141 0.000
N36 Other disorders of urethra
0.858 0.142 0.000
M86-M90 Other osteopathies
0.857 0.143 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.853 0.147 0.000
F41.2 Mixed anxiety and depressive disorder
0.847 0.153 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.846 0.154 0.000
N13.4 Hydroureter
0.845 0.155 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.844 0.156 0.000
N21 Calculus of lower urinary tract
0.841 0.159 0.000
D05.1 Intraductal carcinoma in situ
0.841 0.159 0.000
N13.8 Other obstructive and reflux uropathy
0.840 0.160 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.839 0.161 0.000
C50.8 Overlapping lesion of breast
0.838 0.162 0.000
L71.9 Rosacea, unspecified
0.837 0.163 0.000
M15-M19 Arthrosis
0.837 0.163 0.000
N30.4 Irradiation cystitis
0.836 0.164 0.000
Chapter XXII Codes for special purposes
0.836 0.164 0.000
M54.59 Low back pain (Site unspecified)
0.835 0.165 0.000
Chapter VI Diseases of the nervous system
0.834 0.166 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.833 0.167 0.000
O48 Prolonged pregnancy
0.833 0.167 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.832 0.168 0.000
D09 Carcinoma in situ of other and unspecified sites
0.832 0.168 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.830 0.170 0.000
Z60.2 Living alone
0.826 0.174 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.825 0.175 0.000
L73 Other follicular disorders
0.825 0.175 0.000
L90 Atrophic disorders of skin
0.824 0.176 0.000
O23 Infections of genito-urinary tract in pregnancy
0.820 0.180 0.000
N99-N99 Other disorders of the genitourinary system
0.819 0.181 0.000
D10-D36 Benign neoplasms
0.818 0.182 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.815 0.185 0.000
Y43 Primarily systemic agents
0.813 0.187 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.812 0.188 0.000
L90.5 Scar conditions and fibrosis of skin
0.811 0.189 0.000
N10 Acute tubulo-interstitial nephritis
0.810 0.190 0.000
M54.2 Cervicalgia
0.809 0.191 0.000
N11 Chronic tubulo-interstitial nephritis
0.808 0.192 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.807 0.193 0.000
M54.9 Dorsalgia, unspecified
0.806 0.194 0.000
O41 Other disorders of amniotic fluid and membranes
0.805 0.195 0.000
M79.60 Pain in limb (Multiple sites)
0.804 0.195 0.000
M54.56 Low back pain (Lumbar region)
0.803 0.197 0.000
C50.5 Lower-outer quadrant of breast
0.801 0.198 0.000
C77.2 Intra-abdominal lymph nodes
0.801 0.199 0.000
D23 Other benign neoplasms of skin
0.801 0.199 0.000
F43 Reaction to severe stress, and adjustment disorders
0.801 0.199 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.801 0.199 0.000
S80-S89 Injuries to the knee and lower leg
0.801 0.199 0.000
S06 Intracranial injury
0.798 0.202 0.000
S05 Injury of eye and orbit
0.795 0.205 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.795 0.205 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.794 0.206 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.793 0.207 0.000
M40-M43 Deforming dorsopathies
0.792 0.208 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.792 0.208 0.000
N00-N08 Glomerular diseases
0.792 0.208 0.000
Z03.1 Observation for suspected malignant neoplasm
0.791 0.209 0.000
O44 Placenta praevia
0.790 0.210 0.000
O32.1 Maternal care for breech presentation
0.790 0.210 0.000
O26.8 Other specified pregnancy-related conditions
0.789 0.211 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.787 0.213 0.000
T66-T78 Other and unspecified effects of external causes
0.786 0.214 0.000
N18 Chronic renal failure
0.786 0.214 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.784 0.216 0.000
Chapter VIII Diseases of the ear and mastoid process
0.784 0.216 0.000
Z32 Pregnancy examination and test
0.784 0.216 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.781 0.219 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.781 0.219 0.000
F10.0 Acute intoxication
0.780 0.220 0.000
C77.0 Lymph nodes of head, face and neck
0.780 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
O80-O84 Delivery
0.779 0.221 0.000
C80 Malignant neoplasm without specification of site
0.779 0.221 0.000
Z36.9 Antenatal screening, unspecified
0.778 0.222 0.000
M20-M25 Other joint disorders
0.778 0.222 0.000
Chapter I Certain infectious and parasitic diseases
0.778 0.222 0.000
Q43 Other congenital malformations of intestine
0.777 0.223 0.000
V80-V89 Other land transport accidents
0.777 0.223 0.000
N21.0 Calculus in bladder
0.775 0.225 0.000
O40 Polyhydramnios
0.773 0.227 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.771 0.229 0.000
S62 Fracture at wrist and hand level
0.770 0.230 0.000
O30 Multiple gestation
0.770 0.230 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.768 0.232 0.000
Z35 Supervision of high-risk pregnancy
0.767 0.233 0.000
Q50-Q56 Congenital malformations of genital organs
0.767 0.233 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.763 0.237 0.000
O85-O92 Complications predominantly related to the puerperium
0.762 0.237 0.000
S00 Superficial injury of head
0.762 0.238 0.000
N36.2 Urethral caruncle
0.761 0.239 0.000
L20-L30 Dermatitis and eczema
0.759 0.241 0.000
F45 Somatoform disorders
0.759 0.241 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.758 0.242 0.000
M89 Other disorders of bone
0.757 0.243 0.000
M79.66 Pain in limb (Lower leg)
0.756 0.244 0.000
Z63 Other problems related to primary support group, including family circumstances
0.755 0.245 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.753 0.247 0.000
N20 Calculus of kidney and ureter
0.753 0.247 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.753 0.247 0.000
F10.3 Withdrawal state
0.752 0.248 0.000
S70-S79 Injuries to the hip and thigh
0.752 0.248 0.000
M00-M03 Infectious arthropathies
0.750 0.250 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.749 0.251 0.000
D11 Benign neoplasm of major salivary glands
0.748 0.252 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.748 0.252 0.000
N40-N51 Diseases of male genital organs
0.747 0.253 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.747 0.253 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.747 0.253 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
Y40 Systemic antibiotics
0.745 0.255 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.744 0.256 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.744 0.256 0.000
D09.0 Bladder
0.744 0.256 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.743 0.257 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.743 0.257 0.000
M60-M63 Disorders of muscles
0.742 0.258 0.000
D03 Melanoma in situ
0.741 0.259 0.000
C77.8 Lymph nodes of multiple regions
0.739 0.261 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.738 0.262 0.000
O47 False labour
0.738 0.262 0.000
O20 Haemorrhage in early pregnancy
0.738 0.262 0.000
M65-M68 Disorders of synovium and tendon
0.737 0.263 0.000
M79.62 Pain in limb (Upper arm)
0.735 0.265 0.000
F99-F99 Unspecified mental disorder
0.734 0.265 0.000
N23 Unspecified renal colic
0.733 0.267 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
B35-B49 Mycoses
0.730 0.270 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.730 0.270 0.000
M24 Other specific joint derangements
0.730 0.270 0.000
S02 Fracture of skull and facial bones
0.730 0.270 0.000
Z13 Special screening examination for other diseases and disorders
0.730 0.270 0.000
Y43.3 Other antineoplastic drugs
0.729 0.271 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.728 0.272 0.000
Z02 Examination and encounter for administrative purposes
0.728 0.272 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.726 0.274 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.725 0.275 0.000
C64-C68 Malignant neoplasms of urinary tract
0.725 0.275 0.000
M54.6 Pain in thoracic spine
0.725 0.275 0.000
N13.6 Pyonephrosis
0.724 0.276 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.724 0.276 0.000
M25 Other joint disorders, not elsewhere classified
0.724 0.276 0.000
Z01.4 Gynaecological examination (general)(routine)
0.723 0.277 0.000
S64 Injury of nerves at wrist and hand level
0.722 0.278 0.000
O24 Diabetes mellitus in pregnancy
0.721 0.279 0.000
O32.0 Maternal care for unstable lie
0.721 0.279 0.000
Z29 Need for other prophylactic measures
0.721 0.279 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.720 0.280 0.000
M79.1 Myalgia
0.720 0.280 0.000
C50.2 Upper-inner quadrant of breast
0.719 0.281 0.000
M79.64 Pain in limb (Hand)
0.718 0.282 0.000
N30.0 Acute cystitis
0.718 0.282 0.000
N19 Unspecified renal failure
0.718 0.282 0.000
G30-G32 Other degenerative diseases of the nervous system
0.718 0.282 0.000
L73.8 Other specified follicular disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.716 0.284 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.716 0.284 0.000
C77.5 Intrapelvic lymph nodes
0.716 0.284 0.000
M71 Other bursopathies
0.715 0.285 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.714 0.286 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.714 0.286 0.000
N15 Other renal tubulo-interstitial diseases
0.714 0.286 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.714 0.286 0.000
O26.9 Pregnancy-related condition, unspecified
0.713 0.287 0.000
Y88 Sequelae of surgical and medical care as external cause
0.712 0.287 0.000
Z01.8 Other specified special examinations
0.712 0.288 0.000
O45 Premature separation of placenta [abruptio placentae]
0.712 0.288 0.000
O43 Placental disorders
0.712 0.288 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.712 0.288 0.000
O33 Maternal care for known or suspected disproportion
0.712 0.288 0.000
O31 Complications specific to multiple gestation
0.712 0.288 0.000
D23.6 Skin of upper limb, including shoulder
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
N37 Urethral disorders in diseases classified elsewhere
0.711 0.289 0.000
N34 Urethritis and urethral syndrome
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.711 0.289 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.711 0.289 0.000
M16 Coxarthrosis [arthrosis of hip]
0.711 0.289 0.000
F42 Obsessive-compulsive disorder
0.709 0.291 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.709 0.291 0.000
D04 Carcinoma in situ of skin
0.708 0.292 0.000
F30-F39 Mood [affective] disorders
0.707 0.293 0.000
L50-L54 Urticaria and erythema
0.707 0.293 0.000
Z01.2 Dental examination
0.707 0.293 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.706 0.294 0.000
O34.1 Maternal care for tumour of corpus uteri
0.706 0.294 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.705 0.294 0.000
F43.2 Adjustment disorders
0.705 0.295 0.000
M54.57 Low back pain (Lumbosacral region)
0.704 0.296 0.000
S05.8 Other injuries of eye and orbit
0.704 0.296 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.704 0.296 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
F80-F89 Disorders of psychological development
0.702 0.298 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.701 0.299 0.000
S65 Injury of blood vessels at wrist and hand level
0.701 0.299 0.000
M54.3 Sciatica
0.701 0.299 0.000
Z39 Postpartum care and examination
0.700 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.700 0.300 0.000
N18.4 Chronic kidney disease, stage 4
0.700 0.300 0.000
M79.7 Fibromyalgia
0.699 0.301 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.697 0.303 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
M91-M94 Chondropathies
0.696 0.304 0.000
M80-M85 Disorders of bone density and structure
0.694 0.306 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.693 0.307 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.307 0.000
M79.5 Residual foreign body in soft tissue
0.693 0.307 0.000
D27 Benign neoplasm of ovary
0.693 0.307 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.692 0.308 0.000
Y10-Y34 Event of undetermined intent
0.692 0.308 0.000
Y00-Y09 Assault
0.692 0.308 0.000
X85-X99 Assault
0.692 0.308 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.692 0.308 0.000
X30-X39 Exposure to forces of nature
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.692 0.308 0.000
X10-X19 Contact with heat and hot substances
0.692 0.308 0.000
X00-X09 Exposure to smoke, fire and flames
0.692 0.308 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.692 0.308 0.000
W75-W84 Other accidental threats to breathing
0.692 0.308 0.000
W65-W74 Accidental drowning and submersion
0.692 0.308 0.000
W50-W64 Exposure to animate mechanical forces
0.692 0.308 0.000
V98-V99 Other and unspecified transport accidents
0.692 0.308 0.000
V95-V97 Air and space transport accidents
0.692 0.308 0.000
V90-V94 Water transport accidents
0.692 0.308 0.000
V70-V79 Bus occupant injured in transport accident
0.692 0.308 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
V40-V49 Car occupant injured in transport accident
0.692 0.308 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.692 0.308 0.000
V01-V09 Pedestrian injured in transport accident
0.692 0.308 0.000
S10-S19 Injuries to the neck
0.691 0.309 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.690 0.310 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.690 0.310 0.000
D23.1 Skin of eyelid, including canthus
0.690 0.310 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.690 0.310 0.000
N39.4 Other specified urinary incontinence
0.689 0.311 0.000
M79.67 Pain in limb (Ankle and foot)
0.689 0.311 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.688 0.312 0.000
Q60-Q64 Congenital malformations of the urinary system
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.687 0.313 0.000
Y52 Agents primarily affecting the cardiovascular system
0.687 0.313 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.687 0.313 0.000
O29 Complications of anaesthesia during pregnancy
0.687 0.313 0.000
O28 Abnormal findings on antenatal screening of mother
0.687 0.313 0.000
O22 Venous complications in pregnancy
0.687 0.313 0.000
O21 Excessive vomiting in pregnancy
0.687 0.313 0.000
O25 Malnutrition in pregnancy
0.687 0.313 0.000
M79.69 Pain in limb (Site unspecified)
0.686 0.314 0.000
M89.9 Disorder of bone, unspecified
0.685 0.314 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.685 0.315 0.000
Q80-Q89 Other congenital malformations
0.685 0.315 0.000
Q35-Q37 Cleft lip and cleft palate
0.685 0.315 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.685 0.315 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.685 0.315 0.000
Q00-Q07 Congenital malformations of the nervous system
0.685 0.315 0.000
Q43.0 Meckel's diverticulum
0.685 0.315 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.685 0.315 0.000
M41 Scoliosis
0.685 0.315 0.000
F48 Other neurotic disorders
0.684 0.316 0.000
F44 Dissociative [conversion] disorders
0.684 0.316 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.684 0.316 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.684 0.316 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.684 0.316 0.000
Z32.0 Pregnancy, not (yet) confirmed
0.684 0.316 0.000
N02 Recurrent and persistent haematuria
0.684 0.316 0.000
N60-N64 Disorders of breast
0.684 0.316 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.682 0.318 0.000
S89 Other and unspecified injuries of lower leg
0.682 0.318 0.000
C50.4 Upper-outer quadrant of breast
0.682 0.318 0.000
M76 Enthesopathies of lower limb, excluding foot
0.682 0.318 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.682 0.318 0.000
N36.3 Prolapsed urethral mucosa
0.681 0.319 0.000
L85 Other epidermal thickening
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
D23.5 Skin of trunk
0.681 0.319 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.681 0.319 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.680 0.320 0.000
M54.8 Other dorsalgia
0.680 0.320 0.000
M54.0 Panniculitis affecting regions of neck and back
0.680 0.320 0.000
D11.0 Parotid gland
0.680 0.320 0.000
F01 Vascular dementia
0.679 0.321 0.000
S01 Open wound of head
0.679 0.321 0.000
D05.0 Lobular carcinoma in situ
0.679 0.321 0.000
C50.0 Nipple and areola
0.679 0.321 0.000
F00 Dementia in Alzheimer's disease
0.679 0.321 0.000
C50.6 Axillary tail of breast
0.678 0.322 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.678 0.322 0.000
Z46 Fitting and adjustment of other devices
0.677 0.323 0.000
M54.50 Low back pain (Multiple sites in spine)
0.677 0.323 0.000
N41 Inflammatory diseases of prostate
0.677 0.323 0.000
M54.22 Cervicalgia (Cervical region)
0.677 0.323 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.676 0.324 0.000
X60-X84 Intentional self-harm
0.676 0.324 0.000
M16.9 Coxarthrosis, unspecified
0.675 0.325 0.000
N39.2 Orthostatic proteinuria, unspecified
0.675 0.325 0.000
N39.1 Persistent proteinuria, unspecified
0.675 0.325 0.000
B37 Candidiasis
0.674 0.326 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.674 0.326 0.000
M79.9 Soft tissue disorder, unspecified
0.674 0.326 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.674 0.326 0.000
M79.3 Panniculitis, unspecified
0.674 0.326 0.000
M79.2 Neuralgia and neuritis, unspecified
0.674 0.326 0.000
Y84.0 Cardiac catheterisation
0.672 0.328 0.000
L73.2 Hidradenitis suppurativa
0.671 0.329 0.000
D23.3 Skin of other and unspecified parts of face
0.670 0.330 0.000
O41.0 Oligohydramnios
0.670 0.330 0.000
M79.0 Rheumatism, unspecified
0.670 0.330 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.669 0.331 0.000
Z03.4 Observation for suspected myocardial infarction
0.669 0.331 0.000
Z38 Liveborn infants according to place of birth
0.668 0.332 0.000
M79.68 Pain in limb (Other)
0.668 0.332 0.000
M79.61 Pain in limb (Shoulder region)
0.668 0.332 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.667 0.333 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.333 0.000
M25.4 Effusion of joint
0.666 0.334 0.000
M54.1 Radiculopathy
0.665 0.334 0.000
Z43 Attention to artificial openings
0.665 0.335 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.664 0.336 0.000
Z75 Problems related to medical facilities and other health care
0.664 0.336 0.000
Z65 Problems related to other psychosocial circumstances
0.664 0.336 0.000
Z64 Problems related to certain psychosocial circumstances
0.664 0.336 0.000
Z62 Other problems related to upbringing
0.664 0.336 0.000
Z61 Problems related to negative life events in childhood
0.664 0.336 0.000
Z59 Problems related to housing and economic circumstances
0.664 0.336 0.000
Z58 Problems related to physical environment
0.664 0.336 0.000
Z56 Problems related to employment and unemployment
0.664 0.336 0.000
Z55 Problems related to education and literacy
0.664 0.336 0.000
L75 Apocrine sweat disorders
0.662 0.338 0.000
L74 Eccrine sweat disorders
0.662 0.338 0.000
L70 Acne
0.662 0.338 0.000
L68 Hypertrichosis
0.662 0.338 0.000
L67 Hair colour and hair shaft abnormalities
0.662 0.338 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.662 0.338 0.000
L65 Other nonscarring hair loss
0.662 0.338 0.000
L64 Androgenic alopecia
0.662 0.338 0.000
L63 Alopecia areata
0.662 0.338 0.000
L62 Nail disorders in diseases classified elsewhere
0.662 0.338 0.000
C50.1 Central portion of breast
0.662 0.338 0.000
S08 Traumatic amputation of part of head
0.662 0.338 0.000
S07 Crushing injury of head
0.662 0.338 0.000
S04 Injury of cranial nerves
0.662 0.338 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.662 0.338 0.000
F06.7 Mild cognitive disorder
0.662 0.338 0.000
O42 Premature rupture of membranes
0.661 0.339 0.000
N18.3 Chronic kidney disease, stage 3
0.661 0.339 0.000
Y57 Other and unspecified drugs and medicaments
0.661 0.339 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.660 0.340 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.660 0.340 0.000
O34.6 Maternal care for abnormality of vagina
0.660 0.340 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.660 0.340 0.000
O34.4 Maternal care for other abnormalities of cervix
0.660 0.340 0.000
O34.3 Maternal care for cervical incompetence
0.660 0.340 0.000
O34.0 Maternal care for congenital malformation of uterus
0.660 0.340 0.000
M17 Gonarthrosis [arthrosis of knee]
0.660 0.340 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.660 0.340 0.000
Z10 Routine general health check-up of defined subpopulation
0.659 0.341 0.000
Z33 Pregnant state, incidental
0.659 0.341 0.000
Z46.6 Fitting and adjustment of urinary device
0.657 0.343 0.000
T79-T79 Certain early complications of trauma
0.656 0.344 0.000
Y89 Sequelae of other external causes
0.656 0.344 0.000
C15-C26 Malignant neoplasms of digestive organs
0.656 0.344 0.000
Z31 Procreative management
0.655 0.345 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.654 0.346 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.654 0.346 0.000
O36 Maternal care for other known or suspected foetal problems
0.653 0.347 0.000
Z01.6 Radiological examination, not elsewhere classified
0.653 0.347 0.000
Y85 Sequelae of transport accidents
0.652 0.347 0.000
M54.55 Low back pain (Thoracolumbar region)
0.652 0.348 0.000
M54.54 Low back pain-Thoracic
0.652 0.348 0.000
M54.53 Low back pain-Cervicothoracic
0.652 0.348 0.000
M54.52 Low back pain-Cervical
0.652 0.348 0.000
M54.51 Low back pain-Occipit-atl-axl
0.652 0.348 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.652 0.348 0.000
M25.5 Pain in joint
0.651 0.349 0.000
N64 Other disorders of breast
0.650 0.350 0.000
M24.1 Other articular cartilage disorders
0.649 0.351 0.000
F40 Phobic anxiety disorders
0.648 0.352 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.648 0.352 0.000
O46.9 Antepartum haemorrhage, unspecified
0.648 0.352 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.648 0.352 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.648 0.352 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.648 0.352 0.000
Z36.5 Antenatal screening for isoimmunisation
0.647 0.353 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.647 0.353 0.000
M54.4 Lumbago with sciatica
0.647 0.353 0.000
T78 Adverse effects, not elsewhere classified
0.647 0.353 0.000
N30.3 Trigonitis
0.647 0.353 0.000
L83 Acanthosis nigricans
0.647 0.353 0.000
F10.2 Dependence syndrome
0.646 0.354 0.000
O44.1 Placenta praevia with haemorrhage
0.645 0.355 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.644 0.355 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.644 0.356 0.000
D23.0 Skin of lip
0.644 0.356 0.000
M50 Cervical disk disorders
0.644 0.356 0.000
D06 Carcinoma in situ of cervix uteri
0.643 0.357 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.642 0.358 0.000
N30.2 Other chronic cystitis
0.642 0.358 0.000
C79.6 Secondary malignant neoplasm of ovary
0.641 0.359 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.641 0.359 0.000
O32.8 Maternal care for other malpresentation of foetus
0.641 0.359 0.000
O32.6 Maternal care for compound presentation
0.641 0.359 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.641 0.359 0.000
O32.4 Maternal care for high head at term
0.641 0.359 0.000
O32.3 Maternal care for face, brow and chin presentation
0.641 0.359 0.000
O32.2 Maternal care for transverse and oblique lie
0.641 0.359 0.000
L82 Seborrhoeic keratosis
0.640 0.360 0.000
N30.1 Interstitial cystitis (chronic)
0.640 0.360 0.000
F10.4 Withdrawal state with delirium
0.639 0.361 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.638 0.362 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.638 0.362 0.000
H65-H75 Diseases of middle ear and mastoid
0.638 0.362 0.000
F41.8 Other specified anxiety disorders
0.637 0.362 0.000
F41.3 Other mixed anxiety disorders
0.637 0.362 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.637 0.363 0.000
S60 Superficial injury of wrist and hand
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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