TreeWAS – Variant ID: rs115935509

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XI Diseases of the digestive system	1.000	0.000
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
K55-K64 Other diseases of intestines	1.000	0.000
H40 Glaucoma	1.000	0.000
H40-H42 Glaucoma	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter VII Diseases of the eye and adnexa	0.999	0.001
K62 Other diseases of anus and rectum	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.998	0.002
K70-K77 Diseases of liver	0.998	0.002
H40.1 Primary open-angle glaucoma	0.998	0.002
H40.9 Glaucoma, unspecified	0.998	0.002
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.997	0.003
D00-D09 In situ neoplasms	0.996	0.004
D10-D36 Benign neoplasms	0.995	0.005
D05 Carcinoma in situ of breast	0.989	0.011
K62.8 Other specified diseases of anus and rectum	0.986	0.014
K70 Alcoholic liver disease	0.985	0.015
D12.5 Sigmoid colon	0.984	0.016
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.979	0.021
K62.3 Rectal prolapse	0.979	0.021
K56 Paralytic ileus and intestinal obstruction without hernia	0.975	0.025
D05.9 Carcinoma in situ of breast, unspecified	0.971	0.029
C64-C68 Malignant neoplasms of urinary tract	0.970	0.030
B95-B98 Bacterial, viral and other infectious agents	0.966	0.034
K61 Abscess of anal and rectal regions	0.961	0.039
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.956	0.044
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.954	0.046
D12.0 Caecum	0.953	0.047
D12.8 Rectum	0.949	0.051
H40.0 Glaucoma suspect	0.947	0.053
K70.9 Alcoholic liver disease, unspecified	0.942	0.058
M80-M85 Disorders of bone density and structure	0.942	0.058
K74 Fibrosis and cirrhosis of liver	0.942	0.058
C64 Malignant neoplasm of kidney, except renal pelvis	0.942	0.058
Chapter VIII Diseases of the ear and mastoid process	0.940	0.060
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.940	0.060
Chapter XX External causes of morbidity and mortality	0.939	0.061
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.929	0.071
Chapter IX Diseases of the circulatory system	0.927	0.073
B90-B94 Sequelae of infectious and parasitic diseases	0.926	0.074
K61.0 Anal abscess	0.923	0.077
M86-M90 Other osteopathies	0.922	0.078
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.920	0.080
D12.2 Ascending colon	0.918	0.082
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.912	0.088
M81 Osteoporosis without pathological fracture	0.912	0.088
D05.1 Intraductal carcinoma in situ	0.911	0.089
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.905	0.095
K74.6 Other and unspecified cirrhosis of liver	0.899	0.101
M70-M79 Other soft tissue disorders	0.899	0.101
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.897	0.103
S40-S49 Injuries to the shoulder and upper arm	0.896	0.104
I05-I09 Chronic rheumatic heart diseases	0.896	0.104
C15-C26 Malignant neoplasms of digestive organs	0.895	0.105
K56.6 Other and unspecified intestinal obstruction	0.887	0.113
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.883	0.117
D12.7 Rectosigmoid junction	0.883	0.117
K56.7 Ileus, unspecified	0.882	0.118
M05-M14 Inflammatory polyarthropathies	0.880	0.120
B91 Sequelae of poliomyelitis	0.874	0.126
D06 Carcinoma in situ of cervix uteri	0.872	0.128
K70.3 Alcoholic cirrhosis of liver	0.872	0.128
T36-T50 Poisoning by drugs, medicaments and biological substances	0.871	0.129
M81.9 Osteoporosis, unspecified	0.869	0.131
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.867	0.133
K55 Vascular disorders of intestine	0.867	0.133
K35-K38 Diseases of appendix	0.863	0.137
C78.0 Secondary malignant neoplasm of lung	0.855	0.145
D37-D48 Neoplasms of uncertain or unknown behaviour	0.854	0.146
H65-H75 Diseases of middle ear and mastoid	0.853	0.147
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.847	0.153
K62.6 Ulcer of anus and rectum	0.845	0.155
I08 Multiple valve diseases	0.844	0.156
K59 Other functional intestinal disorders	0.844	0.156
S10-S19 Injuries to the neck	0.841	0.159
D12.6 Colon, unspecified	0.840	0.160
B15-B19 Viral hepatitis	0.839	0.161
K62.2 Anal prolapse	0.839	0.161
T51 Toxic effect of alcohol	0.838	0.162
S90-S99 Injuries to the ankle and foot	0.833	0.167
K70.4 Alcoholic hepatic failure	0.829	0.171
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.828	0.171
S80-S89 Injuries to the knee and lower leg	0.827	0.173
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.827	0.173
M89 Other disorders of bone	0.825	0.175
S20-S29 Injuries to the thorax	0.820	0.180
T85 Complications of other internal prosthetic devices, implants and grafts	0.819	0.181
D10 Benign neoplasm of mouth and pharynx	0.818	0.182
H10-H13 Disorders of conjunctiva	0.815	0.185
K72 Hepatic failure, not elsewhere classified	0.814	0.186
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.814	0.186
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.812	0.188
C78.2 Secondary malignant neoplasm of pleura	0.811	0.189
S70-S79 Injuries to the hip and thigh	0.809	0.191
K55.2 Angiodysplasia of colon	0.803	0.197
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.803	0.197
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.802	0.198
M81.99 Osteoporosis, unspecified (Site unspecified)	0.802	0.198
K04 Diseases of pulp and periapical tissues	0.799	0.201
D04 Carcinoma in situ of skin	0.798	0.202
A30-A49 Other bacterial diseases	0.795	0.205
I60-I69 Cerebrovascular diseases	0.795	0.205
K60 Fissure and fistula of anal and rectal regions	0.793	0.207
B50-B64 Protozoal diseases	0.793	0.207
D33 Benign neoplasm of brain and other parts of central nervous system	0.792	0.207
M71 Other bursopathies	0.792	0.207
A50-A64 Infections with a predominantly sexual mode of transmission	0.791	0.209
H60-H62 Diseases of external ear	0.790	0.210
T51.0 Ethanol	0.790	0.210
D30 Benign neoplasm of urinary organs	0.790	0.210
B35-B49 Mycoses	0.790	0.210
Y60-Y69 Misadventures to patients during surgical and medical care	0.788	0.211
M81.98 Osteoporosis, unspecified (Other)	0.788	0.212
H55-H59 Other disorders of eye and adnexa	0.787	0.213
T66-T78 Other and unspecified effects of external causes	0.786	0.214
I27 Other pulmonary heart diseases	0.785	0.215
D06.9 Cervix, unspecified	0.784	0.216
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.783	0.216
M81.4 Drug-induced osteoporosis	0.779	0.221
I08.1 Disorders of both mitral and tricuspid valves	0.777	0.223
M13 Other arthritis	0.777	0.223
B20-B24 Human immunodeficiency virus [HIV] disease	0.776	0.224
K06 Other disorders of gingiva and edentulous alveolar ridge	0.775	0.225
I70-I79 Diseases of arteries, arterioles and capillaries	0.774	0.226
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.773	0.227
S42 Fracture of shoulder and upper arm	0.772	0.228
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.771	0.229
H46-H48 Disorders of optic nerve and visual pathways	0.771	0.229
K59.0 Constipation	0.770	0.230
K08 Other disorders of teeth and supporting structures	0.770	0.230
K61.3 Ischiorectal abscess	0.766	0.234
H66 Suppurative and unspecified otitis media	0.765	0.235
K56.5 Intestinal adhesions [bands] with obstruction	0.764	0.236
D36 Benign neoplasm of other and unspecified sites	0.762	0.238
M60-M63 Disorders of muscles	0.762	0.238
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.760	0.240
Chapter XXII Codes for special purposes	0.759	0.241
C51-C58 Malignant neoplasms of female genital organs	0.757	0.243
I07 Rheumatic tricuspid valve diseases	0.756	0.244
M79 Other soft tissue disorders, not elsewhere classified	0.756	0.244
K76 Other diseases of liver	0.756	0.244
K02 Dental caries	0.756	0.244
M89.9 Disorder of bone, unspecified	0.755	0.245
M88 Paget's disease of bone [osteitis deformans]	0.755	0.245
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.754	0.245
K12 Stomatitis and related lesions	0.754	0.246
D09 Carcinoma in situ of other and unspecified sites	0.753	0.247
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.752	0.248
T87 Complications peculiar to reattachment and amputation	0.752	0.248
D26 Other benign neoplasms of uterus	0.747	0.252
C78.4 Secondary malignant neoplasm of small intestine	0.747	0.253
H72 Perforation of tympanic membrane	0.747	0.253
I08.0 Disorders of both mitral and aortic valves	0.746	0.254
M06 Other rheumatoid arthritis	0.745	0.255
K56.2 Volvulus	0.744	0.256
D32 Benign neoplasm of meninges	0.744	0.256
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.743	0.257
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.743	0.257
D21 Other benign neoplasms of connective and other soft tissue	0.741	0.259
M91-M94 Chondropathies	0.740	0.260
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.737	0.263
K11 Diseases of salivary glands	0.736	0.264
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.735	0.265
K62.4 Stenosis of anus and rectum	0.735	0.265
M86 Osteomyelitis	0.734	0.266
C66 Malignant neoplasm of ureter	0.731	0.269
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.729	0.271
C67 Malignant neoplasm of bladder	0.728	0.272
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.728	0.272
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.728	0.272
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.727	0.273
K75 Other inflammatory liver diseases	0.726	0.274
M77 Other enthesopathies	0.726	0.274
K38 Other diseases of appendix	0.726	0.274
W20-W49 Exposure to inanimate mechanical forces	0.726	0.274
K09 Cysts of oral region, not elsewhere classified	0.725	0.275
K70.1 Alcoholic hepatitis	0.720	0.280
D24 Benign neoplasm of breast	0.719	0.281
M84 Disorders of continuity of bone	0.719	0.281
C25 Malignant neoplasm of pancreas	0.718	0.282
K65-K67 Diseases of peritoneum	0.718	0.282
T88 Other complications of surgical and medical care, not elsewhere classified	0.718	0.282
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
K64 Haemorrhoids and perianal venous thrombosis	0.717	0.283
H40.8 Other glaucoma	0.717	0.283
H40.6 Glaucoma secondary to drugs	0.717	0.283
H40.4 Glaucoma secondary to eye inflammation	0.717	0.283
H40.3 Glaucoma secondary to eye trauma	0.717	0.283
H42 Glaucoma in diseases classified elsewhere	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S40 Superficial injury of shoulder and upper arm	0.716	0.284
B97 Viral agents as the cause of diseases classified to other chapters	0.716	0.284
B99-B99 Other infectious diseases	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284
B65-B83 Helminthiases	0.716	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284
A75-A79 Rickettsioses	0.716	0.284
A70-A74 Other diseases caused by chlamydiae	0.716	0.284
A65-A69 Other spirochaetal diseases	0.716	0.284
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284
A15-A19 Tuberculosis	0.716	0.284
K77 Liver disorders in diseases classified elsewhere	0.716	0.284
K73 Chronic hepatitis, not elsewhere classified	0.716	0.284
K71 Toxic liver disease	0.716	0.284
D12.9 Anus and anal canal	0.715	0.285
D12.1 Appendix	0.715	0.285
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.715	0.285
D02 Carcinoma in situ of middle ear and respiratory system	0.714	0.286
D01 Carcinoma in situ of other and unspecified digestive organs	0.714	0.286
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.714	0.286
D31 Benign neoplasm of eye and adnexa	0.713	0.286
D29 Benign neoplasm of male genital organs	0.713	0.286
D28 Benign neoplasm of other and unspecified female genital organs	0.713	0.286
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.713	0.286
D19 Benign neoplasm of mesothelial tissue	0.713	0.286
D16 Benign neoplasm of bone and articular cartilage	0.713	0.286
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.713	0.286
H66.9 Otitis media, unspecified	0.713	0.287
H40.5 Glaucoma secondary to other eye disorders	0.712	0.288
V10-V19 Pedal cyclist injured in transport accident	0.712	0.288
D11 Benign neoplasm of major salivary glands	0.711	0.289
D05.7 Other carcinoma in situ of breast	0.709	0.291
D05.0 Lobular carcinoma in situ	0.709	0.291
M13.9 Arthritis, unspecified	0.708	0.292
K56.4 Other impaction of intestine	0.708	0.292
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.708	0.292
K60.2 Anal fissure, unspecified	0.707	0.293
K70.2 Alcoholic fibrosis and sclerosis of liver	0.706	0.294
K70.0 Alcoholic fatty liver	0.706	0.294
Y83.6 Removal of other organ (partial) (total)	0.706	0.294
D04.6 Skin of upper limb, including shoulder	0.705	0.295
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.705	0.295
I27.2 Other secondary pulmonary hypertension	0.704	0.296
M70 Soft tissue disorders related to use, overuse and pressure	0.703	0.296
M00-M03 Infectious arthropathies	0.702	0.298
X20-X29 Contact with venomous animals and plants	0.702	0.298
X60-X84 Intentional self-harm	0.701	0.298
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.299
H90-H95 Other disorders of ear	0.700	0.300
K56.3 Gallstone ileus	0.699	0.301
K56.1 Intussusception	0.699	0.301
K56.0 Paralytic ileus	0.699	0.301
W50-W64 Exposure to animate mechanical forces	0.697	0.303
K04.7 Periapical abscess without sinus	0.696	0.304
M71.2 Synovial cyst of popliteal space [Baker]	0.696	0.304
C68 Malignant neoplasm of other and unspecified urinary organs	0.695	0.305
C65 Malignant neoplasm of renal pelvis	0.695	0.305
I95-I99 Other and unspecified disorders of the circulatory system	0.695	0.305
I05 Rheumatic mitral valve diseases	0.695	0.305
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.694	0.306
S30 Superficial injury of abdomen, lower back and pelvis	0.694	0.306
X40-X49 Accidental poisoning by and exposure to noxious substances	0.694	0.306
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.693	0.307
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.693	0.307
M80 Osteoporosis with pathological fracture	0.693	0.307
D14 Benign neoplasm of middle ear and respiratory system	0.693	0.307
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.693	0.307
W00-W19 Falls	0.690	0.310
Q38-Q45 Other congenital malformations of the digestive system	0.690	0.310
Q60-Q64 Congenital malformations of the urinary system	0.690	0.310
I72 Other aneurysm	0.690	0.310
K61.4 Intrasphincteric abscess	0.689	0.311
K61.2 Anorectal abscess	0.689	0.311
K61.1 Rectal abscess	0.689	0.311
S46 Injury of muscle and tendon at shoulder and upper arm level	0.689	0.311
K74.3 Primary biliary cirrhosis	0.689	0.311
M05 Seropositive rheumatoid arthritis	0.687	0.313
T86 Failure and rejection of transplanted organs and tissues	0.686	0.313
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.685	0.314
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.685	0.314
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.685	0.314
H80-H83 Diseases of inner ear	0.685	0.315
B18 Chronic viral hepatitis	0.685	0.315
C76 Malignant neoplasm of other and ill-defined sites	0.684	0.316
M87 Osteonecrosis	0.684	0.316
C16 Malignant neoplasm of stomach	0.684	0.316
K76.6 Portal hypertension	0.684	0.316
M81.40 Drug-induced osteoporosis (Multiple sites)	0.684	0.316
Chapter VI Diseases of the nervous system	0.683	0.317
A80-A89 Viral infections of the central nervous system	0.683	0.317
D07 Carcinoma in situ of other and unspecified genital organs	0.683	0.317
I67 Other cerebrovascular diseases	0.683	0.317
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.682	0.318
D18 Haemangioma and lymphangioma, any site	0.682	0.318
M13.90 Arthritis, unspecified (Multiple sites)	0.681	0.319
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.681	0.319
I61 Intracerebral haemorrhage	0.681	0.319
H61 Other disorders of external ear	0.680	0.320
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.680	0.320
M40-M43 Deforming dorsopathies	0.679	0.321
I27.0 Primary pulmonary hypertension	0.679	0.321
S19 Other and unspecified injuries of neck	0.678	0.322
Y95 Nosocomial condition	0.677	0.323
H72.0 Central perforation of tympanic membrane	0.676	0.324
T92 Sequelae of injuries of upper limb	0.676	0.324
M83 Adult osteomalacia	0.675	0.325
M82 Osteoporosis in diseases classified elsewhere	0.675	0.325
K74.5 Biliary cirrhosis, unspecified	0.675	0.325
K74.4 Secondary biliary cirrhosis	0.675	0.325
K74.2 Hepatic fibrosis with hepatic sclerosis	0.675	0.325
K74.1 Hepatic sclerosis	0.675	0.325
K74.0 Hepatic fibrosis	0.675	0.325
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.674	0.326
C78.1 Secondary malignant neoplasm of mediastinum	0.674	0.326
H43-H45 Disorders of vitreous body and globe	0.674	0.326
T43.2 Other and unspecified antidepressants	0.674	0.326
Q80-Q89 Other congenital malformations	0.673	0.327
K62.7 Radiation proctitis	0.673	0.327
A41 Other septicaemia	0.673	0.327
S32 Fracture of lumbar spine and pelvis	0.673	0.327
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.673	0.327
Y35-Y36 Legal intervention and operations of war	0.673	0.327
Y10-Y34 Event of undetermined intent	0.673	0.327
Y00-Y09 Assault	0.673	0.327
X85-X99 Assault	0.673	0.327
X58-X59 Accidental exposure to other and unspecified factors	0.673	0.327
X50-X57 Overexertion, travel and privation	0.673	0.327
X30-X39 Exposure to forces of nature	0.673	0.327
X10-X19 Contact with heat and hot substances	0.673	0.327
X00-X09 Exposure to smoke, fire and flames	0.673	0.327
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.673	0.327
W75-W84 Other accidental threats to breathing	0.673	0.327
W65-W74 Accidental drowning and submersion	0.673	0.327
V98-V99 Other and unspecified transport accidents	0.673	0.327
V95-V97 Air and space transport accidents	0.673	0.327
V90-V94 Water transport accidents	0.673	0.327
V80-V89 Other land transport accidents	0.673	0.327
V70-V79 Bus occupant injured in transport accident	0.673	0.327
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.673	0.327
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.673	0.327
V40-V49 Car occupant injured in transport accident	0.673	0.327
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.673	0.327
V01-V09 Pedestrian injured in transport accident	0.673	0.327
S80 Superficial injury of lower leg	0.673	0.327
M79.1 Myalgia	0.672	0.328
Q50-Q56 Congenital malformations of genital organs	0.671	0.329
S81 Open wound of lower leg	0.669	0.330
H30-H36 Disorders of choroid and retina	0.669	0.331
C21 Malignant neoplasm of anus and anal canal	0.668	0.332
K08.3 Retained dental root	0.668	0.332
K62.9 Disease of anus and rectum, unspecified	0.667	0.333
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.666	0.334
K03 Other diseases of hard tissues of teeth	0.666	0.334
K00 Disorders of tooth development and eruption	0.666	0.334
C20 Malignant neoplasm of rectum	0.666	0.334
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.665	0.335
I00-I02 Acute rheumatic fever	0.664	0.335
S42.0 Fracture of clavicle	0.664	0.336
B17 Other acute viral hepatitis	0.664	0.336
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.664	0.336
B90 Sequelae of tuberculosis	0.664	0.336
B92 Sequelae of leprosy	0.664	0.336
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.664	0.336
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.663	0.337
Q00-Q07 Congenital malformations of the nervous system	0.663	0.337
D10.0 Lip	0.663	0.337
Y83.4 Other reconstructive surgery	0.663	0.337
M11 Other crystal arthropathies	0.662	0.338
H11 Other disorders of conjunctiva	0.661	0.338
M90 Osteopathies in diseases classified elsewhere	0.661	0.339
M06.9 Rheumatoid arthritis, unspecified	0.660	0.340
K59.1 Functional diarrhoea	0.660	0.340
S22 Fracture of rib(s), sternum and thoracic spine	0.660	0.340
T83.1 Mechanical complication of other urinary devices and implants	0.660	0.340
H73 Other disorders of tympanic membrane	0.660	0.340
T79-T79 Certain early complications of trauma	0.659	0.341
S14 Injury of nerves and spinal cord at neck level	0.659	0.341
S00-S09 Injuries to the head	0.659	0.341
K37 Unspecified appendicitis	0.657	0.343
I07.1 Tricuspid insufficiency	0.657	0.343
K35 Acute appendicitis	0.656	0.344
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.654	0.346
B07 Viral warts	0.654	0.346
T80 Complications following infusion, transfusion and therapeutic injection	0.654	0.346
M81.8 Other osteoporosis	0.654	0.346
M81.6 Localised osteoporosis [Lequesne]	0.654	0.346
M81.5 Idiopathic osteoporosis	0.654	0.346
M81.3 Postsurgical malabsorption osteoporosis	0.654	0.346
M81.2 Osteoporosis of disuse	0.654	0.346
M81.1 Postoophorectomy osteoporosis	0.654	0.346
M81.0 Postmenopausal osteoporosis	0.654	0.346
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.653	0.347
C18 Malignant neoplasm of colon	0.652	0.348
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.652	0.348
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.652	0.348
I64 Stroke, not specified as haemorrhage or infarction	0.650	0.350
T65 Toxic effect of other and unspecified substances	0.649	0.351
T63 Toxic effect of contact with venomous animals	0.649	0.351
T62 Toxic effect of other noxious substances eaten as food	0.649	0.351
T61 Toxic effect of noxious substances eaten as seafood	0.649	0.351
T60 Toxic effect of pesticides	0.649	0.351
T59 Toxic effect of other gases, fumes and vapours	0.649	0.351
T57 Toxic effect of other inorganic substances	0.649	0.351
T56 Toxic effect of metals	0.649	0.351
T54 Toxic effect of corrosive substances	0.649	0.351
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.649	0.351
T52 Toxic effect of organic solvents	0.649	0.351
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.649	0.351
T58 Toxic effect of carbon monoxide	0.649	0.351
T55 Toxic effect of soaps and detergents	0.649	0.351
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.648	0.352
K72.9 Hepatic failure, unspecified	0.648	0.352
D33.3 Cranial nerves	0.647	0.353
B25-B34 Other viral diseases	0.646	0.353
K62.1 Rectal polyp	0.646	0.354
K10 Other diseases of jaws	0.646	0.354
G30-G32 Other degenerative diseases of the nervous system	0.646	0.354
B59 Pneumocystosis	0.646	0.354
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.645	0.355
M76 Enthesopathies of lower limb, excluding foot	0.644	0.355
M73 Soft tissue disorders in diseases classified elsewhere	0.644	0.355
K05 Gingivitis and periodontal diseases	0.644	0.356
M65-M68 Disorders of synovium and tendon	0.643	0.357
M85 Other disorders of bone density and structure	0.643	0.357
S91 Open wound of ankle and foot	0.643	0.357
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.643	0.357
D30.3 Bladder	0.643	0.357
C80 Malignant neoplasm without specification of site	0.643	0.357
S49 Other and unspecified injuries of shoulder and upper arm	0.642	0.358
S48 Traumatic amputation of shoulder and upper arm	0.642	0.358
S45 Injury of blood vessels at shoulder and upper arm level	0.642	0.358
S44 Injury of nerves at shoulder and upper arm level	0.642	0.358
S41 Open wound of shoulder and upper arm	0.642	0.358
S47 Crushing injury of shoulder and upper arm	0.642	0.358
I09 Other rheumatic heart diseases	0.642	0.358
I06 Rheumatic aortic valve diseases	0.642	0.358
C17 Malignant neoplasm of small intestine	0.642	0.358
C23 Malignant neoplasm of gallbladder	0.642	0.358
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.641	0.358
S42.3 Fracture of shaft of humerus	0.641	0.359
C15 Malignant neoplasm of oesophagus	0.640	0.360
K12.0 Recurrent oral aphthae	0.640	0.360
I74 Arterial embolism and thrombosis	0.640	0.360
S92 Fracture of foot, except ankle	0.640	0.360
T83.3 Mechanical complication of intra-uterine contraceptive device	0.639	0.361
Q20-Q28 Congenital malformations of the circulatory system	0.638	0.362
M72 Fibroblastic disorders	0.637	0.363
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.637	0.363
T87.6 Other and unspecified complications of amputation stump	0.637	0.363
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.635	0.365
M88.9 Paget's disease of bone, unspecified	0.635	0.365
I08.8 Other multiple valve diseases	0.634	0.366
I98 Other disorders of circulatory system in diseases classified elsewhere	0.634	0.366
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.634	0.366
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.634	0.366
T91 Sequelae of injuries of neck and trunk	0.633	0.367
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.633	0.367
K02.8 Other dental caries	0.633	0.367
S10 Superficial injury of neck	0.633	0.367
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.633	0.367
Q35-Q37 Cleft lip and cleft palate	0.633	0.367
Q30-Q34 Congenital malformations of the respiratory system	0.633	0.367
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.633	0.367
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.633	0.367
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.632	0.368
M14 Arthropathies in other diseases classified elsewhere	0.631	0.369
M12 Other specific arthropathies	0.631	0.369
M09 Juvenile arthritis in diseases classified elsewhere	0.631	0.369
M08 Juvenile arthritis	0.631	0.369
S42.1 Fracture of scapula	0.631	0.369
I71 Aortic aneurysm and dissection	0.631	0.369
K72.0 Acute and subacute hepatic failure	0.631	0.369
D12.4 Descending colon	0.630	0.370
D10.3 Other and unspecified parts of mouth	0.630	0.370
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.629	0.371
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.629	0.371
K38.8 Other specified diseases of appendix	0.628	0.372
B00 Herpesviral [herpes simplex] infections	0.627	0.372
S20 Superficial injury of thorax	0.627	0.373
C26 Malignant neoplasm of other and ill-defined digestive organs	0.626	0.373
Y91 Evidence of alcohol involvement determined by level of intoxication	0.626	0.374
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.626	0.374
D06.7 Other parts of cervix	0.625	0.374
D06.1 Exocervix	0.625	0.374
D06.0 Endocervix	0.625	0.374
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.625	0.375
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.624	0.376
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.624	0.376
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.624	0.376
T46 Poisoning by agents primarily affecting the cardiovascular system	0.624	0.376
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.624	0.376
T41 Poisoning by anaesthetics and therapeutic gases	0.624	0.376
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.624	0.376
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.624	0.376
T36 Poisoning by systemic antibiotics	0.624	0.376
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.623	0.377
M81.96 Osteoporosis, unspecified (Lower leg)	0.623	0.377
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.623	0.377
M81.94 Osteoporosis, unspecified (Hand)	0.623	0.377
M81.93 Osteoporosis, unspecified (Forearm)	0.623	0.377
M81.92 Osteoporosis, unspecified (Upper arm)	0.623	0.377
M81.91 Osteoporosis, unspecified (Shoulder region)	0.623	0.377
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.623	0.377
S70 Superficial injury of hip and thigh	0.623	0.377

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations