TreeWAS – Variant ID: rs115939538

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
J40-J47 Chronic lower respiratory diseases	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.995	0.005
C15-C26 Malignant neoplasms of digestive organs	0.992	0.008
Chapter VIII Diseases of the ear and mastoid process	0.991	0.009
Chapter VII Diseases of the eye and adnexa	0.989	0.011
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.984	0.016
Chapter XX External causes of morbidity and mortality	0.978	0.022
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.977	0.023
J90-J94 Other diseases of pleura	0.976	0.024
S60-S69 Injuries to the wrist and hand	0.971	0.029
C18 Malignant neoplasm of colon	0.970	0.030
Chapter XXI Factors influencing health status and contact with health services	0.963	0.037
H65-H75 Diseases of middle ear and mastoid	0.960	0.040
J95-J99 Other diseases of the respiratory system	0.958	0.042
J44 Other chronic obstructive pulmonary disease	0.957	0.043
J47 Bronchiectasis	0.955	0.045
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.952	0.048
Z40-Z54 Persons encountering health services for specific procedures and health care	0.942	0.058
C85.1 B-cell lymphoma, unspecified	0.931	0.069
Z00-Z13 Persons encountering health services for examination and investigation	0.929	0.071
Z08 Follow-up examination after treatment for malignant neoplasm	0.927	0.073
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.927	0.073
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.925	0.075
Chapter V Mental and behavioural disorders	0.923	0.077
S64 Injury of nerves at wrist and hand level	0.922	0.078
C64-C68 Malignant neoplasms of urinary tract	0.921	0.079
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.919	0.081
R63.4 Abnormal weight loss	0.916	0.084
R63 Symptoms and signs concerning food and fluid intake	0.916	0.084
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.916	0.084
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.915	0.085
C18.7 Sigmoid colon	0.914	0.086
R50-R69 General symptoms and signs	0.914	0.086
M20-M25 Other joint disorders	0.910	0.090
J98 Other respiratory disorders	0.910	0.090
H60-H62 Diseases of external ear	0.907	0.093
M05-M14 Inflammatory polyarthropathies	0.905	0.095
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.904	0.096
H65 Nonsuppurative otitis media	0.902	0.098
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.900	0.100
R91 Abnormal findings on diagnostic imaging of lung	0.900	0.100
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.899	0.101
H40-H42 Glaucoma	0.899	0.101
S40-S49 Injuries to the shoulder and upper arm	0.898	0.102
R59 Enlarged lymph nodes	0.894	0.106
M70-M79 Other soft tissue disorders	0.891	0.109
J93 Pneumothorax	0.891	0.109
S64.4 Injury of digital nerve of other finger	0.888	0.112
C45 Mesothelioma	0.886	0.114
M25 Other joint disorders, not elsewhere classified	0.882	0.118
J40 Bronchitis, not specified as acute or chronic	0.881	0.119
J91 Pleural effusion in conditions classified elsewhere	0.879	0.121
J98.1 Pulmonary collapse	0.877	0.123
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.877	0.123
W20-W49 Exposure to inanimate mechanical forces	0.874	0.126
J44.9 Chronic obstructive pulmonary disease, unspecified	0.872	0.128
F30-F39 Mood [affective] disorders	0.870	0.130
M79 Other soft tissue disorders, not elsewhere classified	0.870	0.130
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.868	0.132
S90-S99 Injuries to the ankle and foot	0.868	0.132
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.867	0.133
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.865	0.135
M25.7 Osteophyte	0.862	0.138
R59.9 Enlarged lymph nodes, unspecified	0.860	0.140
J46 Status asthmaticus	0.859	0.141
C92 Myeloid leukaemia	0.857	0.143
C18.9 Colon, unspecified	0.855	0.145
Z43 Attention to artificial openings	0.849	0.151
M13 Other arthritis	0.845	0.155
H43-H45 Disorders of vitreous body and globe	0.845	0.155
R59.1 Generalised enlarged lymph nodes	0.844	0.156
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.843	0.157
Chapter XI Diseases of the digestive system	0.842	0.158
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.837	0.163
C67 Malignant neoplasm of bladder	0.834	0.166
H40 Glaucoma	0.834	0.166
Z51 Other medical care	0.834	0.166
M79.8 Other specified soft tissue disorders	0.829	0.171
Z41 Procedures for purposes other than remedying health state	0.828	0.172
K50-K52 Noninfective enteritis and colitis	0.828	0.172
S80-S89 Injuries to the knee and lower leg	0.827	0.173
C19 Malignant neoplasm of rectosigmoid junction	0.826	0.174
F32 Depressive episode	0.826	0.174
J99 Respiratory disorders in diseases classified elsewhere	0.825	0.175
H10-H13 Disorders of conjunctiva	0.824	0.176
H46-H48 Disorders of optic nerve and visual pathways	0.822	0.178
S20-S29 Injuries to the thorax	0.822	0.178
Z47 Other orthopaedic follow-up care	0.822	0.178
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.819	0.181
H90-H95 Other disorders of ear	0.818	0.182
Y45.0 Opioids and related analgesics	0.818	0.182
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.816	0.184
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.814	0.185
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.814	0.186
H61 Other disorders of external ear	0.809	0.191
R63.0 Anorexia	0.807	0.193
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.805	0.195
D37-D48 Neoplasms of uncertain or unknown behaviour	0.805	0.195
R93 Abnormal findings on diagnostic imaging of other body structures	0.803	0.197
T92 Sequelae of injuries of upper limb	0.802	0.198
C45.0 Mesothelioma of pleura	0.802	0.198
C49 Malignant neoplasm of other connective and soft tissue	0.802	0.198
M13.9 Arthritis, unspecified	0.798	0.202
Z51.1 Chemotherapy session for neoplasm	0.797	0.203
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.796	0.204
H40.0 Glaucoma suspect	0.795	0.205
J93.9 Pneumothorax, unspecified	0.795	0.205
S40 Superficial injury of shoulder and upper arm	0.795	0.205
T36-T50 Poisoning by drugs, medicaments and biological substances	0.794	0.206
D00-D09 In situ neoplasms	0.793	0.207
H55-H59 Other disorders of eye and adnexa	0.793	0.207
S10-S19 Injuries to the neck	0.793	0.207
C81 Hodgkin's disease	0.792	0.207
M25.78 Osteophyte (Other)	0.791	0.209
F32.9 Depressive episode, unspecified	0.791	0.209
K51 Ulcerative colitis	0.790	0.210
H50 Other strabismus	0.789	0.211
H66 Suppurative and unspecified otitis media	0.788	0.212
V20-V29 Motorcycle rider injured in transport accident	0.787	0.213
C91 Lymphoid leukaemia	0.787	0.213
D50-D53 Nutritional anaemias	0.786	0.214
H65.3 Chronic mucoid otitis media	0.783	0.217
Z43.2 Attention to ileostomy	0.783	0.217
Z04 Examination and observation for other reasons	0.780	0.220
Z45 Adjustment and management of implanted device	0.779	0.221
M45-M49 Spondylopathies	0.778	0.222
M40-M43 Deforming dorsopathies	0.774	0.225
C83 Diffuse non-Hodgkin's lymphoma	0.774	0.226
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.774	0.226
J60-J70 Lung diseases due to external agents	0.773	0.227
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.772	0.228
C18.5 Splenic flexure	0.771	0.228
H25-H28 Disorders of lens	0.771	0.229
H71 Cholesteatoma of middle ear	0.769	0.230
J92 Pleural plaque	0.769	0.231
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.769	0.231
Z50 Care involving use of rehabilitation procedures	0.768	0.232
H43 Disorders of vitreous body	0.768	0.232
M13.99 Arthritis, unspecified (Site unspecified)	0.766	0.234
C67.9 Bladder, unspecified	0.765	0.235
M34 Systemic sclerosis	0.765	0.235
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.764	0.236
C22.1 Intrahepatic bile duct carcinoma	0.763	0.237
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.760	0.240
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.760	0.240
S66 Injury of muscle and tendon at wrist and hand level	0.759	0.241
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.759	0.241
M79.6 Pain in limb	0.758	0.242
J98.8 Other specified respiratory disorders	0.756	0.244
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.756	0.244
H69 Other disorders of Eustachian tube	0.756	0.244
J93.8 Other pneumothorax	0.752	0.248
J45 Asthma	0.752	0.248
H60 Otitis externa	0.752	0.248
C78.1 Secondary malignant neoplasm of mediastinum	0.751	0.249
X60-X84 Intentional self-harm	0.751	0.249
W00-W19 Falls	0.750	0.250
Y40 Systemic antibiotics	0.749	0.251
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.746	0.254
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.746	0.254
C18.6 Descending colon	0.746	0.254
J09-J18 Influenza and pneumonia	0.745	0.255
M00-M03 Infectious arthropathies	0.745	0.255
J42 Unspecified chronic bronchitis	0.742	0.258
M25.8 Other specified joint disorders	0.740	0.260
S67 Crushing injury of wrist and hand	0.738	0.262
S62 Fracture at wrist and hand level	0.738	0.262
T66-T78 Other and unspecified effects of external causes	0.738	0.262
C78.7 Secondary malignant neoplasm of liver	0.738	0.262
K12 Stomatitis and related lesions	0.737	0.263
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.737	0.263
J94 Other pleural conditions	0.734	0.266
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.734	0.266
H65.9 Nonsuppurative otitis media, unspecified	0.734	0.266
M25.71 Osteophyte (Shoulder region)	0.733	0.266
M60-M63 Disorders of muscles	0.733	0.267
T79-T79 Certain early complications of trauma	0.732	0.268
M79.86 Other specified soft tissue disorders (Lower leg)	0.732	0.268
R61 Hyperhidrosis	0.732	0.268
S61 Open wound of wrist and hand	0.732	0.268
J99.8 Respiratory disorders in other diseases classified elsewhere	0.730	0.270
J90 Pleural effusion, not elsewhere classified	0.730	0.270
T92.2 Sequelae of fracture at wrist and hand level	0.730	0.270
C22.0 Liver cell carcinoma	0.730	0.270
J00-J06 Acute upper respiratory infections	0.730	0.270
Z42 Follow-up care involving plastic surgery	0.728	0.272
D04 Carcinoma in situ of skin	0.728	0.272
H65.2 Chronic serous otitis media	0.727	0.273
D50 Iron deficiency anaemia	0.727	0.273
C20 Malignant neoplasm of rectum	0.726	0.274
X40-X49 Accidental poisoning by and exposure to noxious substances	0.725	0.275
S69 Other and unspecified injuries of wrist and hand	0.725	0.275
C45.7 Mesothelioma of other sites	0.724	0.276
C18.3 Hepatic flexure	0.720	0.280
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.719	0.280
H61.2 Impacted cerumen	0.718	0.282
Z11 Special screening examination for infectious and parasitic diseases	0.718	0.282
R68 Other general symptoms and signs	0.717	0.283
W22 Striking against or struck by other objects	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C64 Malignant neoplasm of kidney, except renal pelvis	0.716	0.284
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.284
J41 Simple and mucopurulent chronic bronchitis	0.715	0.284
T33-T35 Frostbite	0.715	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.284
T00-T07 Injuries involving multiple body regions	0.715	0.284
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.715	0.285
M86-M90 Other osteopathies	0.715	0.285
H11 Other disorders of conjunctiva	0.714	0.286
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.714	0.286
C22.9 Liver, unspecified	0.714	0.286
M21 Other acquired deformities of limbs	0.714	0.286
C15 Malignant neoplasm of oesophagus	0.714	0.286
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.713	0.287
C95 Leukaemia of unspecified cell type	0.713	0.287
C94 Other leukaemias of specified cell type	0.713	0.287
C93 Monocytic leukaemia	0.713	0.287
C88 Malignant immunoproliferative diseases	0.713	0.287
C86 Other specified types of T/NK-cell lymphoma	0.713	0.287
C84 Peripheral and cutaneous T-cell lymphomas	0.713	0.287
M91-M94 Chondropathies	0.713	0.287
Chapter XXII Codes for special purposes	0.713	0.287
S46 Injury of muscle and tendon at shoulder and upper arm level	0.712	0.288
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.712	0.288
H74 Other disorders of middle ear and mastoid	0.711	0.289
C26 Malignant neoplasm of other and ill-defined digestive organs	0.711	0.289
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.711	0.289
C21 Malignant neoplasm of anus and anal canal	0.711	0.289
C17 Malignant neoplasm of small intestine	0.711	0.289
C23 Malignant neoplasm of gallbladder	0.711	0.289
C18.4 Transverse colon	0.711	0.289
K65-K67 Diseases of peritoneum	0.711	0.289
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.709	0.291
M20 Acquired deformities of fingers and toes	0.709	0.291
M25.74 Osteophyte (Hand)	0.709	0.291
C92.0 Acute myeloid leukaemia	0.708	0.292
C66 Malignant neoplasm of ureter	0.708	0.292
W25 Contact with sharp glass	0.708	0.292
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.707	0.293
C80 Malignant neoplasm without specification of site	0.707	0.293
H65.4 Other chronic nonsuppurative otitis media	0.706	0.294
F40-F48 Neurotic, stress-related and somatoform disorders	0.706	0.294
K52 Other non-infective gastro-enteritis and colitis	0.705	0.295
K12.1 Other forms of stomatitis	0.704	0.296
J98.9 Respiratory disorder, unspecified	0.704	0.296
K50 Crohn's disease [regional enteritis]	0.703	0.297
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.701	0.298
Y35-Y36 Legal intervention and operations of war	0.701	0.298
Y10-Y34 Event of undetermined intent	0.701	0.298
Y00-Y09 Assault	0.701	0.298
X85-X99 Assault	0.701	0.298
X58-X59 Accidental exposure to other and unspecified factors	0.701	0.298
X50-X57 Overexertion, travel and privation	0.701	0.298
X30-X39 Exposure to forces of nature	0.701	0.298
X20-X29 Contact with venomous animals and plants	0.701	0.298
X10-X19 Contact with heat and hot substances	0.701	0.298
X00-X09 Exposure to smoke, fire and flames	0.701	0.298
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.701	0.298
W75-W84 Other accidental threats to breathing	0.701	0.298
W65-W74 Accidental drowning and submersion	0.701	0.298
W50-W64 Exposure to animate mechanical forces	0.701	0.298
V98-V99 Other and unspecified transport accidents	0.701	0.298
V95-V97 Air and space transport accidents	0.701	0.298
V90-V94 Water transport accidents	0.701	0.298
V70-V79 Bus occupant injured in transport accident	0.701	0.298
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.701	0.298
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.701	0.298
V40-V49 Car occupant injured in transport accident	0.701	0.298
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.701	0.298
V01-V09 Pedestrian injured in transport accident	0.701	0.298
H72 Perforation of tympanic membrane	0.701	0.299
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.701	0.299
C85.7 Other specified types of non-Hodgkin's lymphoma	0.701	0.299
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.701	0.299
C85.0 Lymphosarcoma	0.701	0.299
M79.89 Other specified soft tissue disorders (Site unspecified)	0.701	0.299
S90 Superficial injury of ankle and foot	0.700	0.300
M24 Other specific joint derangements	0.700	0.300
V80-V89 Other land transport accidents	0.700	0.300
M10 Gout	0.700	0.300
T93 Sequelae of injuries of lower limb	0.699	0.301
Z52 Donors of organs and tissues	0.698	0.302
D60-D64 Aplastic and other anaemias	0.698	0.302
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.697	0.303
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.697	0.303
Y60-Y69 Misadventures to patients during surgical and medical care	0.697	0.303
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.696	0.304
S65 Injury of blood vessels at wrist and hand level	0.696	0.304
C18.8 Overlapping lesion of colon	0.695	0.305
C18.1 Appendix	0.695	0.305
C92.1 Chronic myeloid leukaemia	0.695	0.305
Y86 Sequelae of other accidents	0.694	0.306
C49.3 Connective and soft tissue of thorax	0.694	0.306
S82 Fracture of lower leg, including ankle	0.693	0.307
J80-J84 Other respiratory diseases principally affecting the interstitium	0.693	0.307
J20-J22 Other acute lower respiratory infections	0.692	0.308
C79 Secondary malignant neoplasm of other sites	0.691	0.309
C78.0 Secondary malignant neoplasm of lung	0.691	0.309
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.688	0.311
H70 Mastoiditis and related conditions	0.688	0.311
H68 Eustachian salpingitis and obstruction	0.688	0.311
H67 Otitis media in diseases classified elsewhere	0.688	0.311
J96 Respiratory failure, not elsewhere classified	0.687	0.313
T15-T19 Effects of foreign body entering through natural orifice	0.687	0.313
R60 Oedema, not elsewhere classified	0.687	0.313
Y45.1 Salicylates	0.686	0.314
H47 Other disorders of optic [2nd] nerve and visual pathways	0.685	0.315
H92 Otalgia and effusion of ear	0.685	0.315
C73 Malignant neoplasm of thyroid gland	0.684	0.316
M13.98 Arthritis, unspecified (Other)	0.683	0.317
Z51.5 Palliative care	0.683	0.317
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.683	0.317
C46 Kaposi's sarcoma	0.683	0.317
R63.1 Polydipsia	0.682	0.318
K51.2 Ulcerative (chronic) proctitis	0.682	0.318
S70-S79 Injuries to the hip and thigh	0.681	0.319
R94 Abnormal results of function studies	0.681	0.319
Y57 Other and unspecified drugs and medicaments	0.681	0.319
C71 Malignant neoplasm of brain	0.681	0.319
C16 Malignant neoplasm of stomach	0.680	0.319
H43.8 Other disorders of vitreous body	0.679	0.321
F31 Bipolar affective disorder	0.679	0.321
M25.76 Osteophyte (Lower leg)	0.679	0.321
Y52 Agents primarily affecting the cardiovascular system	0.678	0.322
R80 Isolated proteinuria	0.678	0.322
S91 Open wound of ankle and foot	0.677	0.323
S61.9 Open wound of wrist and hand, part unspecified	0.676	0.324
Z54 Convalescence	0.675	0.325
Z44 Fitting and adjustment of external prosthetic device	0.675	0.325
M79.0 Rheumatism, unspecified	0.675	0.325
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.675	0.325
M07 Psoriatic and enteropathic arthropathies	0.674	0.326
W29 Contact with other powered hand tools and household machinery	0.674	0.326
J44.8 Other specified chronic obstructive pulmonary disease	0.674	0.326
C50-C50 Malignant neoplasm of breast	0.672	0.328
S22 Fracture of rib(s), sternum and thoracic spine	0.672	0.328
S63.6 Sprain and strain of finger(s)	0.672	0.328
K52.8 Other specified non-infective gastro-enteritis and colitis	0.671	0.329
K51.3 Ulcerative (chronic) rectosigmoiditis	0.671	0.329
T91 Sequelae of injuries of neck and trunk	0.671	0.329
C45.9 Mesothelioma, unspecified	0.671	0.329
F60-F69 Disorders of adult personality and behaviour	0.670	0.330
C81.1 Nodular sclerosis	0.669	0.331
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.668	0.332
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.668	0.332
Z10 Routine general health check-up of defined subpopulation	0.666	0.334
S60 Superficial injury of wrist and hand	0.666	0.334
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.665	0.335
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.665	0.335
M13.90 Arthritis, unspecified (Multiple sites)	0.665	0.335
Y59 Other and unspecified vaccines and biological substances	0.665	0.335
Y58 Bacterial vaccines	0.665	0.335
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.665	0.335
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.665	0.335
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.665	0.335
Y53 Agents primarily affecting the gastro-intestinal system	0.665	0.335
Y50 Central nervous system stimulants, not elsewhere classified	0.665	0.335
Y49 Psychotropic drugs, not elsewhere classified	0.665	0.335
Y48 Anaesthetics and therapeutic gases	0.665	0.335
Y47 Sedatives, hypnotics and antianxiety drugs	0.665	0.335
Y46 Antiepileptics and anti-Parkinsonism drugs	0.665	0.335
Y41 Other systemic anti-infectives and antiparasitics	0.665	0.335
Y51 Drugs primarily affecting the autonomic nervous system	0.664	0.336
S92 Fracture of foot, except ankle	0.664	0.336
R95-R99 Ill-defined and unknown causes of mortality	0.663	0.336
Z49 Care involving dialysis	0.663	0.337
C18.0 Caecum	0.663	0.337
M25.3 Other instability of joint	0.662	0.338
Z57 Occupational exposure to risk-factors	0.662	0.338
Q60-Q64 Congenital malformations of the urinary system	0.662	0.338
F99-F99 Unspecified mental disorder	0.662	0.338
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.662	0.338
F70-F79 Mental retardation	0.662	0.338
Y43 Primarily systemic agents	0.662	0.338
S64.9 Injury of unspecified nerve at wrist and hand level	0.661	0.339
S64.8 Injury of other nerves at wrist and hand level	0.661	0.339
S64.7 Injury of multiple nerves at wrist and hand level	0.661	0.339
S64.3 Injury of digital nerve of thumb	0.661	0.339
S64.2 Injury of radial nerve at wrist and hand level	0.661	0.339
S64.1 Injury of median nerve at wrist and hand level	0.661	0.339
S64.0 Injury of ulnar nerve at wrist and hand level	0.661	0.339
C68 Malignant neoplasm of other and unspecified urinary organs	0.661	0.339
C65 Malignant neoplasm of renal pelvis	0.661	0.339
K04 Diseases of pulp and periapical tissues	0.659	0.341
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.659	0.341
Q38-Q45 Other congenital malformations of the digestive system	0.658	0.342
H80-H83 Diseases of inner ear	0.658	0.342
D50.9 Iron deficiency anaemia, unspecified	0.657	0.343
R63.6 Insufficient intake of food and water due to self neglect	0.657	0.343
R63.5 Abnormal weight gain	0.657	0.343
R63.3 Feeding difficulties and mismanagement	0.657	0.343
R63.2 Polyphagia	0.657	0.343
K51.9 Ulcerative colitis, unspecified	0.657	0.343
H50.0 Convergent concomitant strabismus	0.657	0.343
R92 Abnormal findings on diagnostic imaging of breast	0.656	0.343
C76 Malignant neoplasm of other and ill-defined sites	0.656	0.344
S40.0 Contusion of shoulder and upper arm	0.656	0.344
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.655	0.345
R62 Lack of expected normal physiological development	0.655	0.345
R64 Cachexia	0.655	0.345
R58 Haemorrhage, not elsewhere classified	0.655	0.345
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.655	0.345
W44 Foreign body entering into or through eye or natural orifice	0.654	0.346
Chapter I Certain infectious and parasitic diseases	0.654	0.346
M50-M54 Other dorsopathies	0.653	0.347
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.653	0.347
M33 Dermatopolymyositis	0.653	0.347
M32 Systemic lupus erythematosus	0.653	0.347
M30 Polyarteritis nodosa and related conditions	0.653	0.347
J98.6 Disorders of diaphragm	0.653	0.347
J98.5 Diseases of mediastinum, not elsewhere classified	0.653	0.347
J98.3 Compensatory emphysema	0.653	0.347
J98.2 Interstitial emphysema	0.653	0.347
H61.3 Acquired stenosis of external ear canal	0.652	0.348
M79.60 Pain in limb (Multiple sites)	0.652	0.348
S49 Other and unspecified injuries of shoulder and upper arm	0.652	0.348
M48 Other spondylopathies	0.652	0.348
H62 Disorders of external ear in diseases classified elsewhere	0.650	0.349
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.650	0.349
D46 Myelodysplastic syndromes	0.650	0.350
M14 Arthropathies in other diseases classified elsewhere	0.649	0.351
M12 Other specific arthropathies	0.649	0.351
M09 Juvenile arthritis in diseases classified elsewhere	0.649	0.351
M08 Juvenile arthritis	0.649	0.351
H50.1 Divergent concomitant strabismus	0.649	0.351
M31 Other necrotising vasculopathies	0.649	0.351
H65.1 Other acute nonsuppurative otitis media	0.647	0.353
H65.0 Acute serous otitis media	0.647	0.353
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.647	0.353
T98 Sequelae of other and unspecified effects of external causes	0.645	0.355
T95 Sequelae of burns, corrosions and frostbite	0.645	0.355
T94 Sequelae of injuries involving multiple and unspecified body regions	0.645	0.355
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.645	0.355
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.645	0.355
C22.7 Other specified carcinomas of liver	0.645	0.355
C22.4 Other sarcomas of liver	0.645	0.355
C22.3 Angiosarcoma of liver	0.645	0.355
C22.2 Hepatoblastoma	0.645	0.355
Z51.8 Other specified medical care	0.645	0.355
M79.84 Other specified soft tissue disorders (Hand)	0.645	0.355
M79.7 Fibromyalgia	0.644	0.356
H42 Glaucoma in diseases classified elsewhere	0.644	0.356
S48 Traumatic amputation of shoulder and upper arm	0.644	0.356
S45 Injury of blood vessels at shoulder and upper arm level	0.644	0.356
S44 Injury of nerves at shoulder and upper arm level	0.644	0.356
S41 Open wound of shoulder and upper arm	0.644	0.356
S47 Crushing injury of shoulder and upper arm	0.644	0.356
F32.3 Severe depressive episode with psychotic symptoms	0.644	0.356
D04.9 Skin, unspecified	0.644	0.356
Z45.0 Adjustment and management of cardiac pacemaker	0.644	0.356
K51.8 Other ulcerative colitis	0.643	0.356
M25.77 Osteophyte (Ankle and foot)	0.643	0.357
Z43.6 Attention to other artificial openings of urinary tract	0.643	0.357
T90 Sequelae of injuries of head	0.643	0.357
F52 Sexual dysfunction, not caused by organic disorder or disease	0.643	0.357
R63.8 Other symptoms and signs concerning food and fluid intake	0.643	0.357
Z51.3 Blood transfusion without reported diagnosis	0.643	0.357
H50.9 Strabismus, unspecified	0.642	0.358
Z12 Special screening examination for neoplasms	0.642	0.358
F80-F89 Disorders of psychological development	0.641	0.358
M79.80 Other specified soft tissue disorders (Multiple sites)	0.641	0.359
C18.2 Ascending colon	0.641	0.359
K07 Dentofacial anomalies [including malocclusion]	0.640	0.360
H60.9 Otitis externa, unspecified	0.640	0.360
J03 Acute tonsillitis	0.640	0.360
M20.0 Deformity of finger(s)	0.639	0.361
M70 Soft tissue disorders related to use, overuse and pressure	0.639	0.361
D55-D59 Haemolytic anaemias	0.639	0.361
M76 Enthesopathies of lower limb, excluding foot	0.639	0.361
M73 Soft tissue disorders in diseases classified elsewhere	0.639	0.361
J93.0 Spontaneous tension pneumothorax	0.639	0.361
D10-D36 Benign neoplasms	0.639	0.361
C91.1 Chronic lymphocytic leukaemia	0.638	0.362
M25.75 Osteophyte (Pelvic region and thigh)	0.638	0.362
Q80-Q89 Other congenital malformations	0.636	0.364
M25.6 Stiffness of joint, not elsewhere classified	0.636	0.364
C45.2 Mesothelioma of pericardium	0.635	0.364
C45.1 Mesothelioma of peritoneum	0.635	0.364
M11 Other crystal arthropathies	0.635	0.365
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.635	0.365
R57 Shock, not elsewhere classified	0.634	0.366
H91 Other hearing loss	0.633	0.367
M25.9 Joint disorder, unspecified	0.632	0.368
M25.2 Flail joint	0.632	0.368
M25.1 Fistula of joint	0.632	0.368
M25.0 Haemarthrosis	0.632	0.368
M43 Other deforming dorsopathies	0.631	0.368
M71 Other bursopathies	0.631	0.369
M25.86 Other specified joint disorders (Lower leg)	0.631	0.369
H27 Other disorders of lens	0.630	0.370
D63 Anaemia in chronic diseases classified elsewhere	0.630	0.370
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.630	0.370
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.629	0.371

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations