TreeWAS – Variant ID: rs11600200

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I20.0 Unstable angina	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	0.999	0.001	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.997	0.003	0.000
I25.2 Old myocardial infarction	0.985	0.015	0.000
I21 Acute myocardial infarction	0.983	0.017	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.978	0.022	0.000
I21.9 Acute myocardial infarction, unspecified	0.960	0.040	0.000
I21.4 Acute subendocardial myocardial infarction	0.937	0.063	0.000
I22 Subsequent myocardial infarction	0.932	0.068	0.000
I25.5 Ischaemic cardiomyopathy	0.905	0.095	0.000
I25.3 Aneurysm of heart	0.864	0.136	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.860	0.140	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.835	0.165	0.000
I23 Certain current complications following acute myocardial infarction	0.823	0.177	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.812	0.188	0.000
I22.8 Subsequent myocardial infarction of other sites	0.790	0.210	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.772	0.228	0.000
I20.8 Other forms of angina pectoris	0.725	0.275	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.721	0.279	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.705	0.295	0.000
I23.8 Other current complications following acute myocardial infarction	0.696	0.304	0.000
I44.7 Left bundle-branch block, unspecified	0.655	0.345	0.000
I20.1 Angina pectoris with documented spasm	0.651	0.349	0.000
I44 Atrioventricular and left bundle-branch block	0.647	0.353	0.000
I42.9 Cardiomyopathy, unspecified	0.646	0.354	0.000
I42 Cardiomyopathy	0.646	0.354	0.000
I30-I52 Other forms of heart disease	0.640	0.360	0.000
I50 Heart failure	0.622	0.378	0.000
I42.0 Dilated cardiomyopathy	0.622	0.378	0.000
I50.1 Left ventricular failure	0.617	0.383	0.000
Chapter IX Diseases of the circulatory system	0.616	0.384	0.000
I25.4 Coronary artery aneurysm	0.596	0.404	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.590	0.410	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.590	0.410	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.590	0.410	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.590	0.410	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.590	0.410	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.590	0.410	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.590	0.410	0.000
I44.2 Atrioventricular block, complete	0.581	0.419	0.000
I05-I09 Chronic rheumatic heart diseases	0.555	0.445	0.000
I42.5 Other restrictive cardiomyopathy	0.533	0.467	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.527	0.473	0.000
I33 Acute and subacute endocarditis	0.527	0.473	0.000
I44.4 Left anterior fascicular block	0.524	0.476	0.000
I08 Multiple valve diseases	0.512	0.488	0.000
I44.6 Other and unspecified fascicular block	0.494	0.506	0.000
I42.6 Alcoholic cardiomyopathy	0.482	0.518	0.000
I47 Paroxysmal tachycardia	0.482	0.518	0.000
I08.0 Disorders of both mitral and aortic valves	0.481	0.519	0.000
I40 Acute myocarditis	0.469	0.531	0.000
I30 Acute pericarditis	0.465	0.535	0.000
I44.5 Left posterior fascicular block	0.464	0.536	0.000
I42.4 Endocardial fibroelastosis	0.463	0.537	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.463	0.537	0.000
I52 Other heart disorders in diseases classified elsewhere	0.459	0.541	0.000
I48 Atrial fibrillation and flutter	0.459	0.541	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.459	0.541	0.000
I41 Myocarditis in diseases classified elsewhere	0.459	0.541	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.459	0.541	0.000
I32 Pericarditis in diseases classified elsewhere	0.459	0.541	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.459	0.541	0.000
I47.0 Reentry ventricular arrhythmia	0.452	0.548	0.000
I44.3 Other and unspecified atrioventricular block	0.449	0.551	0.000
I05 Rheumatic mitral valve diseases	0.447	0.553	0.000
I08.8 Other multiple valve diseases	0.446	0.554	0.000
I45 Other conduction disorders	0.443	0.557	0.000
I00-I02 Acute rheumatic fever	0.441	0.558	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.440	0.560	0.000
I33.9 Acute endocarditis, unspecified	0.431	0.569	0.000
I24 Other acute ischaemic heart diseases	0.427	0.573	0.000
I36 Nonrheumatic tricuspid valve disorders	0.424	0.576	0.000
I50.0 Congestive heart failure	0.424	0.576	0.000
I51 Complications and ill-defined descriptions of heart disease	0.423	0.577	0.000
I09 Other rheumatic heart diseases	0.422	0.578	0.000
I37 Pulmonary valve disorders	0.417	0.583	0.000
I51.8 Other ill-defined heart diseases	0.410	0.590	0.000
I05.0 Mitral stenosis	0.410	0.590	0.000
I42.8 Other cardiomyopathies	0.409	0.591	0.000
I06 Rheumatic aortic valve diseases	0.403	0.597	0.000
I33.0 Acute and subacute infective endocarditis	0.401	0.598	0.000
I30.9 Acute pericarditis, unspecified	0.393	0.607	0.000
I45.2 Bifascicular block	0.390	0.610	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.383	0.617	0.000
I47.2 Ventricular tachycardia	0.373	0.627	0.000
I40.9 Acute myocarditis, unspecified	0.365	0.634	0.000
I45.8 Other specified conduction disorders	0.358	0.642	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.355	0.645	0.000
I45.3 Trifascicular block	0.351	0.649	0.000
I08.9 Multiple valve disease, unspecified	0.350	0.650	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.340	0.660	0.000
I40.8 Other acute myocarditis	0.337	0.663	0.000
I40.1 Isolated myocarditis	0.337	0.663	0.000
I05.2 Mitral stenosis with insufficiency	0.334	0.666	0.000
I30.8 Other forms of acute pericarditis	0.333	0.667	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.333	0.667	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.329	0.671	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.329	0.671	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.329	0.671	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.329	0.671	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.329	0.671	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.329	0.671	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.329	0.671	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.329	0.671	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.329	0.671	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.329	0.671	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.329	0.671	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.329	0.671	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.329	0.671	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.329	0.671	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.329	0.671	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.329	0.671	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.329	0.671	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.329	0.671	0.000
I48.4 Atypical atrial flutter	0.329	0.671	0.000
I48.3 Typical atrial flutter	0.329	0.671	0.000
I48.2 Chronic atrial fibrillation	0.329	0.671	0.000
I48.1 Persistent atrial fibrillation	0.329	0.671	0.000
I48.0 Paroxysmal atrial fibrillation	0.329	0.671	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.329	0.671	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.329	0.671	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.329	0.671	0.000
I09.9 Rheumatic heart disease, unspecified	0.326	0.674	0.000
I50.9 Heart failure, unspecified	0.325	0.675	0.000
I05.8 Other mitral valve diseases	0.321	0.679	0.000
I45.0 Right fascicular block	0.318	0.682	0.000
I51.0 Cardiac septal defect, acquired	0.317	0.683	0.000
I02 Rheumatic chorea	0.317	0.683	0.000
I01 Rheumatic fever with heart involvement	0.317	0.683	0.000
I00 Rheumatic fever without mention of heart involvement	0.317	0.683	0.000
I99 Other and unspecified disorders of circulatory system	0.314	0.686	0.000
I44.1 Atrioventricular block, second degree	0.314	0.686	0.000
I40.0 Infective myocarditis	0.313	0.687	0.000
I44.0 Atrioventricular block, first degree	0.312	0.688	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.304	0.696	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.304	0.696	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.304	0.696	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.304	0.696	0.000
I51.5 Myocardial degeneration	0.303	0.696	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.303	0.696	0.000
I09.8 Other specified rheumatic heart diseases	0.302	0.697	0.000
I09.2 Chronic rheumatic pericarditis	0.302	0.697	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.302	0.697	0.000
I09.0 Rheumatic myocarditis	0.302	0.697	0.000
I45.6 Preexcitation syndrome	0.302	0.698	0.000
I37.9 Pulmonary valve disorder, unspecified	0.299	0.701	0.000
I37.8 Other pulmonary valve disorders	0.299	0.701	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.299	0.701	0.000
I37.0 Pulmonary valve stenosis	0.299	0.701	0.000
I45.1 Other and unspecified right bundle-branch block	0.295	0.705	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.293	0.707	0.000
I06.0 Rheumatic aortic stenosis	0.293	0.707	0.000
I05.1 Rheumatic mitral insufficiency	0.289	0.711	0.000
I45.4 Nonspecific intraventricular block	0.289	0.711	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.289	0.711	0.000
I06.8 Other rheumatic aortic valve diseases	0.289	0.711	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.289	0.711	0.000
I06.1 Rheumatic aortic insufficiency	0.289	0.711	0.000
I24.1 Dressler's syndrome	0.282	0.718	0.000
I07 Rheumatic tricuspid valve diseases	0.281	0.718	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.281	0.719	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.278	0.721	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.278	0.721	0.001
I51.6 Cardiovascular disease, unspecified	0.275	0.725	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.269	0.731	0.000
I51.4 Myocarditis, unspecified	0.265	0.735	0.000
I31 Other diseases of pericardium	0.262	0.738	0.000
I51.7 Cardiomegaly	0.260	0.740	0.000
I37.1 Pulmonary valve insufficiency	0.257	0.743	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.251	0.749	0.000
I45.5 Other specified heart block	0.244	0.756	0.000
I46 Cardiac arrest	0.241	0.759	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.236	0.764	0.000
I30.1 Infective pericarditis	0.236	0.764	0.000
I42.2 Other hypertrophic cardiomyopathy	0.231	0.769	0.000
S09.9 Unspecified injury of head	0.231	0.769	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.227	0.773	0.000
I01.8 Other acute rheumatic heart disease	0.227	0.773	0.000
I01.2 Acute rheumatic myocarditis	0.227	0.773	0.000
I01.1 Acute rheumatic endocarditis	0.227	0.773	0.000
I01.0 Acute rheumatic pericarditis	0.227	0.773	0.000
I02.9 Rheumatic chorea without heart involvement	0.227	0.773	0.000
I02.0 Rheumatic chorea with heart involvement	0.227	0.773	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.227	0.773	0.000
I24.8 Other forms of acute ischaemic heart disease	0.223	0.777	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.218	0.782	0.000
I05.9 Mitral valve disease, unspecified	0.214	0.786	0.000
I38 Endocarditis, valve unspecified	0.212	0.788	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.210	0.789	0.000
I97.0 Postcardiotomy syndrome	0.210	0.789	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.210	0.790	0.000
I31.0 Chronic adhesive pericarditis	0.205	0.795	0.000
I07.9 Tricuspid valve disease, unspecified	0.202	0.798	0.000
I07.8 Other tricuspid valve diseases	0.202	0.798	0.000
I07.2 Tricuspid stenosis with insufficiency	0.202	0.798	0.000
I07.0 Tricuspid stenosis	0.202	0.798	0.000
I45.9 Conduction disorder, unspecified	0.188	0.811	0.000
I31.8 Other specified diseases of pericardium	0.188	0.812	0.000
I31.2 Haemopericardium, not elsewhere classified	0.188	0.812	0.000
I31.1 Chronic constrictive pericarditis	0.188	0.812	0.000
I95 Hypotension	0.185	0.815	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.176	0.824	0.000
I46.1 Sudden cardiac death, so described	0.173	0.827	0.000
I95.0 Idiopathic hypotension	0.161	0.839	0.000
I51.9 Heart disease, unspecified	0.156	0.844	0.000
I97.1 Other functional disturbances following cardiac surgery	0.156	0.844	0.000
I95.2 Hypotension due to drugs	0.153	0.847	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.150	0.849	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.150	0.849	0.000
I98.0 Cardiovascular syphilis	0.150	0.849	0.000
I46.0 Cardiac arrest with successful resuscitation	0.147	0.853	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.145	0.855	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.144	0.856	0.000
I34 Nonrheumatic mitral valve disorders	0.134	0.866	0.000
C67 Malignant neoplasm of bladder	0.131	0.869	0.000
C67.1 Dome of bladder	0.129	0.871	0.000
C67.9 Bladder, unspecified	0.128	0.872	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.125	0.875	0.000
I95.8 Other hypotension	0.123	0.877	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.123	0.877	0.000
I49 Other cardiac arrhythmias	0.123	0.877	0.000
I28 Other diseases of pulmonary vessels	0.120	0.880	0.000
C67.4 Posterior wall of bladder	0.114	0.886	0.000
C67.2 Lateral wall of bladder	0.114	0.886	0.000
I31.3 Pericardial effusion (noninflammatory)	0.112	0.888	0.000
S09 Other and unspecified injuries of head	0.111	0.889	0.000
C67.3 Anterior wall of bladder	0.105	0.895	0.000
I49.0 Ventricular fibrillation and flutter	0.104	0.896	0.000
C67.6 Ureteric orifice	0.102	0.898	0.000
C67.0 Trigone of bladder	0.099	0.901	0.000
C67.5 Bladder neck	0.097	0.903	0.000
C67.7 Urachus	0.094	0.906	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.094	0.906	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.093	0.907	0.000
I31.9 Disease of pericardium, unspecified	0.088	0.911	0.000
I26 Pulmonary embolism	0.088	0.912	0.000
I49.2 Junctional premature depolarisation	0.088	0.912	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.087	0.913	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.086	0.914	0.000
I28.1 Aneurysm of pulmonary artery	0.086	0.914	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.086	0.914	0.000
I07.1 Tricuspid insufficiency	0.085	0.914	0.000
S09.2 Traumatic rupture of ear drum	0.085	0.915	0.000
I49.1 Atrial premature depolarisation	0.084	0.916	0.000
C67.8 Overlapping lesion of bladder	0.083	0.917	0.000
S09.8 Other specified injuries of head	0.083	0.917	0.000
S09.7 Multiple injuries of head	0.080	0.920	0.000
S09.1 Injury of muscle and tendon of head	0.080	0.920	0.000
I28.8 Other specified diseases of pulmonary vessels	0.079	0.920	0.000
I49.4 Other and unspecified premature depolarisation	0.078	0.922	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.075	0.924	0.000
I49.3 Ventricular premature depolarisation	0.073	0.927	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.073	0.927	0.000
I10-I15 Hypertensive diseases	0.071	0.929	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.068	0.931	0.000
I49.8 Other specified cardiac arrhythmias	0.061	0.939	0.000
I95.1 Orthostatic hypotension	0.060	0.940	0.000
I35 Nonrheumatic aortic valve disorders	0.060	0.940	0.000
C64-C68 Malignant neoplasms of urinary tract	0.052	0.948	0.000
I13 Hypertensive heart and renal disease	0.051	0.949	0.000
I49.5 Sick sinus syndrome	0.051	0.949	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.043	0.957	0.000
I47.1 Supraventricular tachycardia	0.040	0.960	0.000
I35.9 Aortic valve disorder, unspecified	0.040	0.960	0.000
I35.8 Other aortic valve disorders	0.040	0.960	0.000
I34.0 Mitral (valve) insufficiency	0.039	0.961	0.000
I60-I69 Cerebrovascular diseases	0.039	0.961	0.000
I15 Secondary hypertension	0.038	0.962	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.038	0.962	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.037	0.963	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.037	0.963	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.037	0.963	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.037	0.963	0.000
C68.0 Urethra	0.037	0.963	0.000
I49.9 Cardiac arrhythmia, unspecified	0.036	0.964	0.000
I62 Other nontraumatic intracranial haemorrhage	0.036	0.964	0.000
I46.9 Cardiac arrest, unspecified	0.035	0.964	0.001
I11 Hypertensive heart disease	0.034	0.965	0.000
I12 Hypertensive renal disease	0.034	0.966	0.000
C66 Malignant neoplasm of ureter	0.034	0.966	0.000
I34.1 Mitral (valve) prolapse	0.033	0.967	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.033	0.967	0.000
C68.9 Urinary organ, unspecified	0.031	0.969	0.000
C68.8 Overlapping lesion of urinary organs	0.031	0.969	0.000
C68.1 Paraurethral glands	0.031	0.969	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.030	0.970	0.000
C65 Malignant neoplasm of renal pelvis	0.029	0.971	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.029	0.971	0.000
I15.8 Other secondary hypertension	0.028	0.972	0.000
I15.2 Hypertension secondary to endocrine disorders	0.028	0.972	0.000
I15.0 Renovascular hypertension	0.028	0.972	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.027	0.973	0.000
I62.1 Nontraumatic extradural haemorrhage	0.026	0.974	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.025	0.975	0.000
I63 Cerebral infarction	0.025	0.975	0.000
I12.9 Hypertensive renal disease without renal failure	0.025	0.975	0.000
I69 Sequelae of cerebrovascular disease	0.024	0.976	0.000
I63.8 Other cerebral infarction	0.023	0.977	0.000
I15.9 Seconday hypertension, unspecified	0.023	0.977	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.022	0.978	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.022	0.978	0.000
I15.1 Hypertension secondary to other renal disorders	0.021	0.978	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.022	0.978	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.020	0.979	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.021	0.979	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.021	0.979	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.021	0.979	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.021	0.979	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.021	0.979	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.021	0.979	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.020	0.980	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.020	0.980	0.000
I27 Other pulmonary heart diseases	0.019	0.980	0.001
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.019	0.981	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.019	0.981	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.019	0.981	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.018	0.982	0.000
I68.0 Cerebral amyloid angiopathy	0.018	0.982	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.018	0.982	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.018	0.982	0.000
I63.9 Cerebral infarction, unspecified	0.017	0.983	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.016	0.983	0.000
I69.3 Sequelae of cerebral infarction	0.016	0.984	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.016	0.984	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.016	0.984	0.000
I65.1 Occlusion and stenosis of basilar artery	0.016	0.984	0.000
S00-S09 Injuries to the head	0.016	0.984	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.015	0.984	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.015	0.985	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.015	0.985	0.000
S05 Injury of eye and orbit	0.014	0.986	0.000
I35.1 Aortic (valve) insufficiency	0.014	0.986	0.000
I27.1 Kyphoscoliotic heart disease	0.014	0.986	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.014	0.986	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.014	0.986	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.014	0.986	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.013	0.987	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.013	0.987	0.000
S05.8 Other injuries of eye and orbit	0.013	0.987	0.000
I67 Other cerebrovascular diseases	0.012	0.988	0.000
I95.9 Hypotension, unspecified	0.012	0.988	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.012	0.988	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.012	0.988	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.012	0.988	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.012	0.988	0.000
S08 Traumatic amputation of part of head	0.011	0.988	0.000
S07 Crushing injury of head	0.011	0.988	0.000
S04 Injury of cranial nerves	0.011	0.988	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.011	0.989	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.011	0.989	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.011	0.989	0.000
S06 Intracranial injury	0.011	0.989	0.000
I65.2 Occlusion and stenosis of carotid artery	0.011	0.989	0.000
S05.7 Avulsion of eye	0.010	0.989	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.010	0.989	0.000
I27.8 Other specified pulmonary heart diseases	0.010	0.989	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.010	0.990	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.010	0.990	0.000
S05.1 Contusion of eyeball and orbital tissues	0.010	0.990	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.010	0.990	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.009	0.990	0.000
S00 Superficial injury of head	0.010	0.990	0.000
I87 Other disorders of veins	0.009	0.991	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.009	0.991	0.000
I67.5 Moyamoya disease	0.009	0.991	0.000
I67.4 Hypertensive encephalopathy	0.009	0.991	0.000
I67.3 Progressive vascular leukoencephalopathy	0.009	0.991	0.000
L90.5 Scar conditions and fibrosis of skin	0.009	0.991	0.000
I61 Intracerebral haemorrhage	0.009	0.991	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.009	0.991	0.000
I67.1 Cerebral aneurysm, nonruptured	0.009	0.991	0.000
S03.2 Dislocation of tooth	0.009	0.991	0.000
S06.5 Traumatic subdural haemorrhage	0.009	0.991	0.000
E04.9 Non-toxic goitre, unspecified	0.009	0.991	0.000
S05.9 Injury of eye and orbit, part unspecified	0.009	0.991	0.000
Q28 Other congenital malformations of circulatory system	0.009	0.991	0.000
S00.7 Multiple superficial injuries of head	0.009	0.991	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.008	0.991	0.000
S03.4 Sprain and strain of jaw	0.008	0.991	0.000
S03.3 Dislocation of other and unspecified parts of head	0.008	0.991	0.000
S03.1 Dislocation of septal cartilage of nose	0.008	0.991	0.000
S03.0 Dislocation of jaw	0.008	0.991	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.009	0.991	0.000
S06.8 Other intracranial injuries	0.008	0.991	0.000
S04.9 Injury of unspecified cranial nerve	0.008	0.991	0.000
S04.8 Injury of other cranial nerves	0.008	0.991	0.000
S04.7 Injury of accessory nerve	0.008	0.991	0.000
S04.6 Injury of acoustic nerve	0.008	0.991	0.000
S04.5 Injury of facial nerve	0.008	0.991	0.000
S04.4 Injury of abducent nerve	0.008	0.991	0.000
S04.3 Injury of trigeminal nerve	0.008	0.991	0.000
S04.2 Injury of trochlear nerve	0.008	0.991	0.000
S04.1 Injury of oculomotor nerve	0.008	0.991	0.000
S04.0 Injury of optic nerve and pathways	0.008	0.991	0.000
S07.9 Crushing injury of head, part unspecified	0.008	0.991	0.000
S07.8 Crushing injury of other parts of head	0.008	0.991	0.000
S07.1 Crushing injury of skull	0.008	0.991	0.000
S07.0 Crushing injury of face	0.008	0.991	0.000
S08.9 Traumatic amputation of unspecified part of head	0.008	0.991	0.000
S08.8 Traumatic amputation of other parts of head	0.008	0.991	0.000
S08.1 Traumatic amputation of ear	0.008	0.991	0.000
S08.0 Avulsion of scalp	0.008	0.991	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.008	0.992	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.008	0.992	0.000
I88 Nonspecific lymphadenitis	0.008	0.992	0.000
I27.9 Pulmonary heart disease, unspecified	0.008	0.992	0.001
I27.0 Primary pulmonary hypertension	0.008	0.992	0.000
S00.5 Superficial injury of lip and oral cavity	0.008	0.992	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.008	0.992	0.000
I87.8 Other specified disorders of veins	0.008	0.992	0.000
S00.1 Contusion of eyelid and periocular area	0.008	0.992	0.000
Q28.3 Other malformations of cerebral vessels	0.008	0.992	0.000
S06.7 Intracranial injury with prolonged coma	0.008	0.992	0.000
S06.1 Traumatic cerebral oedema	0.008	0.992	0.000
S00.8 Superficial injury of other parts of head	0.008	0.992	0.000
S06.4 Epidural haemorrhage	0.008	0.992	0.000
I81 Portal vein thrombosis	0.008	0.992	0.000
I67.2 Cerebral atherosclerosis	0.008	0.992	0.000
I86 Varicose veins of other sites	0.008	0.992	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.008	0.992	0.000
L82 Seborrhoeic keratosis	0.008	0.992	0.000
I12.0 Hypertensive renal disease with renal failure	0.008	0.992	0.000
S06.9 Intracranial injury, unspecified	0.008	0.992	0.000
H18.4 Corneal degeneration	0.000	0.992	0.008
L89.9 Decubitus ulcer and pressure area, unspecified	0.008	0.992	0.000
I87.9 Disorder of vein, unspecified	0.007	0.992	0.000
H18.8 Other specified disorders of cornea	0.000	0.992	0.008
L89 Decubitus ulcer	0.008	0.992	0.000
I85 Oesophageal varices	0.007	0.992	0.000
R54 Senility	0.007	0.993	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.007	0.993	0.000
L90 Atrophic disorders of skin	0.007	0.993	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.007	0.993	0.000
H18 Other disorders of cornea	0.000	0.993	0.007
Q27.3 Peripheral arteriovenous malformation	0.007	0.993	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.007	0.993	0.001
H18.5 Hereditary corneal dystrophies	0.000	0.993	0.007
I87.2 Venous insufficiency (chronic) (peripheral)	0.007	0.993	0.000
S06.3 Focal brain injury	0.007	0.993	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.007	0.993	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.007	0.993	0.000
S06.0 Concussion	0.007	0.993	0.000
I87.0 Postphlebitic syndrome	0.007	0.993	0.000
L89.2 Stage III decubitus ulcer	0.007	0.993	0.000
I61.8 Other intracerebral haemorrhage	0.007	0.993	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.007	0.993	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.007	0.993	0.000
I35.0 Aortic (valve) stenosis	0.007	0.993	0.000
I86.2 Pelvic varices	0.007	0.993	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.007	0.993	0.000
S06.2 Diffuse brain injury	0.006	0.993	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.006	0.993	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.006	0.993	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.006	0.993	0.000
Q28.1 Other malformations of precerebral vessels	0.006	0.993	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.006	0.993	0.000
I86.3 Vulval varices	0.006	0.993	0.000
S02 Fracture of skull and facial bones	0.006	0.993	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.006	0.994	0.000
L89.1 Stage II decubitus ulcer	0.006	0.994	0.000
L89.3 Stage IV decubitus ulcer	0.006	0.994	0.000
H18.2 Other corneal oedema	0.000	0.994	0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.006	0.994	0.000
I71 Aortic aneurysm and dissection	0.006	0.994	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.006	0.994	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.006	0.994	0.000
I79.1 Aortitis in diseases classified elsewhere	0.006	0.994	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.006	0.994	0.000
I88.8 Other nonspecific lymphadenitis	0.006	0.994	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.006	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.006	0.994	0.000
I67.8 Other specified cerebrovascular diseases	0.006	0.994	0.000
I77 Other disorders of arteries and arterioles	0.006	0.994	0.000
H33.0 Retinal detachment with retinal break	0.000	0.994	0.006
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.006	0.994	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.006	0.994	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.006	0.994	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.006	0.994	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
I86.0 Sublingual varices	0.006	0.994	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.006	0.994	0.000
I86.4 Gastric varices	0.006	0.994	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.006	0.994	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.006	0.994	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.006	0.994	0.000
I70 Atherosclerosis	0.006	0.994	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.005	0.994	0.000
L90.0 Lichen sclerosus et atrophicus	0.006	0.994	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.994	0.000
B34.9 Viral infection, unspecified	0.006	0.994	0.000
L90.9 Atrophic disorder of skin, unspecified	0.005	0.994	0.000
L90.8 Other atrophic disorders of skin	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations