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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116061333
log Bayes Factor = 14.4818
Chromosome 4   position 157,751,111  (GRCh37) Explore rs116061333 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
A30-A49 Other bacterial diseases
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.991 0.009 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
A41 Other septicaemia
0.985 0.015 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.984 0.016 0.000
E11 Non-insulin-dependent diabetes mellitus
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
E70-E90 Metabolic disorders
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.980 0.020 0.000
C78.0 Secondary malignant neoplasm of lung
0.979 0.021 0.000
Chapter IX Diseases of the circulatory system
0.977 0.023 0.000
B95-B98 Bacterial, viral and other infectious agents
0.975 0.025 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.972 0.028 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.969 0.031 0.000
E78.5 Hyperlipidaemia, unspecified
0.966 0.034 0.000
I20-I25 Ischaemic heart diseases
0.965 0.035 0.000
A41.9 Septicaemia, unspecified
0.965 0.035 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.958 0.042 0.000
E11.9 Without complications
0.957 0.043 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.953 0.047 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.947 0.053 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.946 0.054 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
I21 Acute myocardial infarction
0.939 0.061 0.000
Chapter X Diseases of the respiratory system
0.936 0.064 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.933 0.067 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.928 0.072 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.926 0.074 0.000
S80-S89 Injuries to the knee and lower leg
0.919 0.081 0.000
S00-S09 Injuries to the head
0.915 0.085 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.912 0.088 0.000
L60-L75 Disorders of skin appendages
0.910 0.090 0.000
C15-C26 Malignant neoplasms of digestive organs
0.908 0.092 0.000
I60-I69 Cerebrovascular diseases
0.904 0.096 0.000
H02 Other disorders of eyelid
0.902 0.098 0.000
B35-B49 Mycoses
0.901 0.099 0.000
S00 Superficial injury of head
0.901 0.099 0.000
I25 Chronic ischaemic heart disease
0.896 0.104 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.894 0.106 0.000
H30-H36 Disorders of choroid and retina
0.892 0.108 0.000
E11.3 With ophthalmic complications
0.889 0.111 0.000
A49 Bacterial infection of unspecified site
0.888 0.112 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.886 0.114 0.000
I21.9 Acute myocardial infarction, unspecified
0.885 0.115 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.884 0.116 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.884 0.116 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.880 0.120 0.000
D70 Agranulocytosis
0.877 0.123 0.000
J30-J39 Other diseases of upper respiratory tract
0.875 0.125 0.000
G40-G47 Episodic and paroxysmal disorders
0.874 0.126 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.873 0.127 0.000
S60-S69 Injuries to the wrist and hand
0.869 0.131 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.858 0.142 0.000
A00-A09 Intestinal infectious diseases
0.858 0.142 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.857 0.143 0.000
D60-D64 Aplastic and other anaemias
0.856 0.144 0.000
T86 Failure and rejection of transplanted organs and tissues
0.856 0.144 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.855 0.145 0.000
S00.0 Superficial injury of scalp
0.852 0.148 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.852 0.148 0.000
S00.8 Superficial injury of other parts of head
0.852 0.148 0.000
E11.5 With peripheral circulatory complications
0.851 0.149 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.851 0.149 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.848 0.152 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.848 0.152 0.000
D69 Purpura and other haemorrhagic conditions
0.847 0.153 0.000
J00-J06 Acute upper respiratory infections
0.845 0.155 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.843 0.157 0.000
H02.3 Blepharochalasis
0.839 0.161 0.000
C83.3 Large cell (diffuse)
0.835 0.165 0.000
J95-J99 Other diseases of the respiratory system
0.835 0.165 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.834 0.166 0.000
C78.2 Secondary malignant neoplasm of pleura
0.831 0.169 0.000
X60-X84 Intentional self-harm
0.828 0.172 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.827 0.173 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.826 0.174 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.826 0.174 0.000
H04 Disorders of lachrymal system
0.825 0.175 0.000
Y40 Systemic antibiotics
0.824 0.176 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.823 0.177 0.000
G90-G99 Other disorders of the nervous system
0.821 0.179 0.000
Y52 Agents primarily affecting the cardiovascular system
0.818 0.182 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.817 0.183 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.816 0.184 0.000
J09-J18 Influenza and pneumonia
0.816 0.184 0.000
E50-E64 Other nutritional deficiencies
0.813 0.187 0.000
B37 Candidiasis
0.813 0.187 0.000
D73 Diseases of spleen
0.812 0.188 0.000
I63 Cerebral infarction
0.812 0.188 0.000
A46 Erysipelas
0.810 0.190 0.000
I10-I15 Hypertensive diseases
0.810 0.190 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.808 0.192 0.000
M20-M25 Other joint disorders
0.807 0.193 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.806 0.194 0.000
C64-C68 Malignant neoplasms of urinary tract
0.803 0.197 0.000
A49.0 Staphylococcal infection, unspecified
0.802 0.198 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.800 0.200 0.000
E78.2 Mixed hyperlipidaemia
0.798 0.201 0.000
C51-C58 Malignant neoplasms of female genital organs
0.797 0.203 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.796 0.204 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.794 0.206 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.793 0.207 0.000
C79 Secondary malignant neoplasm of other sites
0.792 0.208 0.000
L90 Atrophic disorders of skin
0.792 0.208 0.000
M25 Other joint disorders, not elsewhere classified
0.791 0.209 0.000
L72.1 Trichilemmal cyst
0.791 0.209 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.791 0.209 0.000
J38.7 Other diseases of larynx
0.790 0.210 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.789 0.211 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.787 0.213 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.787 0.213 0.000
Q80-Q89 Other congenital malformations
0.787 0.213 0.000
H43-H45 Disorders of vitreous body and globe
0.784 0.216 0.000
H36 Retinal disorders in diseases classified elsewhere
0.784 0.216 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.783 0.217 0.000
H02.0 Entropion and trichiasis of eyelid
0.782 0.218 0.000
W20-W49 Exposure to inanimate mechanical forces
0.781 0.219 0.000
E78.8 Other disorders of lipoprotein metabolism
0.780 0.220 0.000
C34 Malignant neoplasm of bronchus and lung
0.778 0.222 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.778 0.222 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.778 0.222 0.000
A04 Other bacterial intestinal infections
0.778 0.222 0.000
A41.8 Other specified septicaemia
0.776 0.224 0.000
Chapter XIV Diseases of the genitourinary system
0.773 0.227 0.000
M25.5 Pain in joint
0.773 0.227 0.000
C16 Malignant neoplasm of stomach
0.772 0.228 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.772 0.228 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.768 0.231 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.767 0.233 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.765 0.235 0.000
Q00-Q07 Congenital malformations of the nervous system
0.764 0.236 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.762 0.238 0.000
Y43 Primarily systemic agents
0.760 0.240 0.000
Y44 Agents primarily affecting blood constituents
0.758 0.242 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.758 0.242 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.758 0.242 0.000
T93 Sequelae of injuries of lower limb
0.756 0.244 0.000
D69.6 Thrombocytopenia, unspecified
0.755 0.245 0.000
H05 Disorders of orbit
0.755 0.245 0.000
H31 Other disorders of choroid
0.755 0.245 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.755 0.245 0.000
E88 Other metabolic disorders
0.754 0.246 0.000
T86.1 Kidney transplant failure and rejection
0.754 0.246 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.753 0.247 0.000
H02.4 Ptosis of eyelid
0.752 0.248 0.000
B65-B83 Helminthiases
0.750 0.250 0.000
L40-L45 Papulosquamous disorders
0.749 0.251 0.000
A04.8 Other specified bacterial intestinal infections
0.749 0.251 0.000
S05 Injury of eye and orbit
0.748 0.252 0.000
E14 Unspecified diabetes mellitus
0.748 0.252 0.000
G47 Sleep disorders
0.748 0.252 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.747 0.253 0.000
L72.0 Epidermal cyst
0.747 0.253 0.000
E11.1 With ketoacidosis
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.743 0.256 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.743 0.257 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.743 0.257 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.743 0.257 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.742 0.258 0.000
N17-N19 Renal failure
0.742 0.258 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.742 0.258 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.741 0.259 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.741 0.259 0.000
H00 Hordeolum and chalazion
0.741 0.259 0.000
S10-S19 Injuries to the neck
0.741 0.259 0.000
B37.0 Candidal stomatitis
0.741 0.259 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.740 0.260 0.000
Q50-Q56 Congenital malformations of genital organs
0.740 0.260 0.000
J98 Other respiratory disorders
0.738 0.262 0.000
I22 Subsequent myocardial infarction
0.737 0.263 0.000
S89 Other and unspecified injuries of lower leg
0.737 0.263 0.000
D68 Other coagulation defects
0.737 0.263 0.000
S50-S59 Injuries to the elbow and forearm
0.737 0.263 0.000
S86 Injury of muscle and tendon at lower leg level
0.736 0.264 0.000
L90.5 Scar conditions and fibrosis of skin
0.735 0.265 0.000
S80 Superficial injury of lower leg
0.733 0.267 0.000
I69 Sequelae of cerebrovascular disease
0.733 0.267 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
J38.3 Other diseases of vocal cords
0.732 0.268 0.000
D66 Hereditary factor VIII deficiency
0.732 0.268 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.731 0.268 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.731 0.269 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.731 0.269 0.000
Q60-Q64 Congenital malformations of the urinary system
0.730 0.270 0.000
N00-N08 Glomerular diseases
0.730 0.270 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.730 0.270 0.000
I25.2 Old myocardial infarction
0.730 0.270 0.000
C32 Malignant neoplasm of larynx
0.729 0.271 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.728 0.272 0.000
D75 Other diseases of blood and blood-forming organs
0.728 0.272 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.727 0.273 0.000
I12 Hypertensive renal disease
0.724 0.276 0.000
G20-G26 Extrapyramidal and movement disorders
0.723 0.277 0.000
Y86 Sequelae of other accidents
0.723 0.277 0.000
E83 Disorders of mineral metabolism
0.723 0.277 0.000
M25.56 Pain in joint (Lower leg)
0.721 0.279 0.000
S82 Fracture of lower leg, including ankle
0.721 0.279 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.719 0.281 0.000
A80-A89 Viral infections of the central nervous system
0.718 0.282 0.000
S67 Crushing injury of wrist and hand
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
C80 Malignant neoplasm without specification of site
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
N18 Chronic renal failure
0.716 0.284 0.000
D73.0 Hyposplenism
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.716 0.284 0.000
J30 Vasomotor and allergic rhinitis
0.715 0.285 0.000
I63.9 Cerebral infarction, unspecified
0.715 0.285 0.000
H10-H13 Disorders of conjunctiva
0.715 0.285 0.000
A48 Other bacterial diseases, not elsewhere classified
0.714 0.286 0.000
A44 Bartonellosis
0.714 0.286 0.000
A43 Nocardiosis
0.714 0.286 0.000
A42 Actinomycosis
0.714 0.286 0.000
A40 Streptococcal septicaemia
0.714 0.286 0.000
A39 Meningococcal infection
0.714 0.286 0.000
A37 Whooping cough
0.714 0.286 0.000
A36 Diphtheria
0.714 0.286 0.000
A32 Listeriosis
0.714 0.286 0.000
A31 Infection due to other mycobacteria
0.714 0.286 0.000
A30 Leprosy [Hansen's disease]
0.714 0.286 0.000
A38 Scarlet fever
0.714 0.286 0.000
A35 Other tetanus
0.714 0.286 0.000
A34 Obstetrical tetanus
0.714 0.286 0.000
A33 Tetanus neonatorum
0.714 0.286 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.714 0.286 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
D46 Myelodysplastic syndromes
0.712 0.288 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.711 0.289 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.711 0.289 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.711 0.289 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.711 0.289 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.710 0.290 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.290 0.000
G43 Migraine
0.709 0.290 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.709 0.291 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
S00.3 Superficial injury of nose
0.708 0.292 0.000
I62 Other nontraumatic intracranial haemorrhage
0.707 0.293 0.000
H36.0 Diabetic retinopathy
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.293 0.000
A41.4 Septicaemia due to anaerobes
0.706 0.293 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.706 0.293 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.706 0.293 0.000
C43 Malignant melanoma of skin
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.706 0.294 0.000
H02.5 Other disorders affecting eyelid function
0.706 0.294 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
J38.2 Nodules of vocal cords
0.706 0.294 0.000
E11.8 With unspecified complications
0.705 0.295 0.000
E11.7 With multiple complications
0.705 0.295 0.000
E11.6 With other specified complications
0.705 0.295 0.000
E11.0 With coma
0.705 0.295 0.000
H33 Retinal detachments and breaks
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
C83.0 Small cell (diffuse)
0.704 0.296 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.703 0.297 0.000
E85 Amyloidosis
0.703 0.297 0.000
E84 Cystic fibrosis
0.703 0.297 0.000
E79 Disorders of purine and pyrimidine metabolism
0.703 0.297 0.000
E77 Disorders of glycoprotein metabolism
0.703 0.297 0.000
E76 Disorders of glycosaminoglycan metabolism
0.703 0.297 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.703 0.297 0.000
E74 Other disorders of carbohydrate metabolism
0.703 0.297 0.000
E73 Lactose intolerance
0.703 0.297 0.000
E72 Other disorders of amino-acid metabolism
0.703 0.297 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.703 0.297 0.000
E70 Disorders of aromatic amino-acid metabolism
0.703 0.297 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.703 0.297 0.000
D72 Other disorders of white blood cells
0.703 0.297 0.000
J36 Peritonsillar abscess
0.703 0.297 0.000
S62 Fracture at wrist and hand level
0.702 0.298 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.701 0.299 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.701 0.299 0.000
I00-I02 Acute rheumatic fever
0.701 0.299 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.701 0.299 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
H02.6 Xanthelasma of eyelid
0.700 0.300 0.000
D00-D09 In situ neoplasms
0.700 0.300 0.000
L89 Decubitus ulcer
0.700 0.300 0.000
M22 Disorders of patella
0.699 0.301 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.698 0.301 0.000
S90-S99 Injuries to the ankle and foot
0.698 0.302 0.000
Y40.0 Penicillins
0.698 0.302 0.000
G81 Hemiplegia
0.698 0.302 0.000
Y95 Nosocomial condition
0.698 0.302 0.000
E78.6 Lipoprotein deficiency
0.697 0.303 0.000
E78.4 Other hyperlipidaemia
0.697 0.303 0.000
E78.3 Hyperchylomicronaemia
0.697 0.303 0.000
E78.1 Pure hyperglyceridaemia
0.697 0.303 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.697 0.303 0.000
I20 Angina pectoris
0.696 0.304 0.000
T79-T79 Certain early complications of trauma
0.696 0.304 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.696 0.304 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.695 0.305 0.000
S68 Traumatic amputation of wrist and hand
0.695 0.305 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.694 0.305 0.000
C95 Leukaemia of unspecified cell type
0.694 0.305 0.000
C94 Other leukaemias of specified cell type
0.694 0.305 0.000
C93 Monocytic leukaemia
0.694 0.305 0.000
C88 Malignant immunoproliferative diseases
0.694 0.305 0.000
C86 Other specified types of T/NK-cell lymphoma
0.694 0.305 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.694 0.306 0.000
J00 Acute nasopharyngitis [common cold]
0.694 0.306 0.000
L73 Other follicular disorders
0.693 0.307 0.000
J18 Pneumonia, organism unspecified
0.693 0.307 0.000
J39 Other diseases of upper respiratory tract
0.693 0.307 0.000
B15-B19 Viral hepatitis
0.693 0.307 0.000
J35 Chronic diseases of tonsils and adenoids
0.693 0.307 0.000
C90.0 Multiple myeloma
0.692 0.308 0.000
L65 Other nonscarring hair loss
0.692 0.308 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.692 0.308 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.692 0.308 0.000
E20-E35 Disorders of other endocrine glands
0.692 0.308 0.000
E87.5 Hyperkalaemia
0.691 0.309 0.000
C25 Malignant neoplasm of pancreas
0.691 0.309 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.691 0.309 0.000
G95 Other diseases of spinal cord
0.691 0.309 0.000
B49 Unspecified mycosis
0.690 0.310 0.000
C79.2 Secondary malignant neoplasm of skin
0.688 0.312 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.687 0.313 0.000
T87 Complications peculiar to reattachment and amputation
0.687 0.313 0.000
J06.9 Acute upper respiratory infection, unspecified
0.687 0.313 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.686 0.314 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.686 0.314 0.000
E11.4 With neurological complications
0.686 0.314 0.000
A49.1 Streptococcal infection, unspecified
0.685 0.315 0.000
C81 Hodgkin's disease
0.684 0.316 0.000
I25.3 Aneurysm of heart
0.684 0.316 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.683 0.317 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.683 0.317 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.683 0.317 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.683 0.317 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.683 0.317 0.000
G82 Paraplegia and tetraplegia
0.682 0.317 0.000
H40-H42 Glaucoma
0.682 0.317 0.000
M05-M14 Inflammatory polyarthropathies
0.682 0.318 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.318 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.680 0.319 0.000
L91 Hypertrophic disorders of skin
0.680 0.320 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.679 0.321 0.000
D74 Methaemoglobinaemia
0.679 0.321 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.679 0.321 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.679 0.321 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
L10-L14 Bullous disorders
0.678 0.322 0.000
T91 Sequelae of injuries of neck and trunk
0.677 0.323 0.000
W00-W19 Falls
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.676 0.324 0.000
E10 Insulin-dependent diabetes mellitus
0.676 0.324 0.000
B25-B34 Other viral diseases
0.675 0.324 0.000
L50-L54 Urticaria and erythema
0.675 0.325 0.000
Q85 Phakomatoses, not elsewhere classified
0.675 0.325 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.673 0.327 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.673 0.327 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.673 0.327 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.672 0.328 0.000
C20 Malignant neoplasm of rectum
0.672 0.328 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.671 0.329 0.000
N10-N16 Renal tubulo-interstitial diseases
0.671 0.329 0.000
S70-S79 Injuries to the hip and thigh
0.671 0.329 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.670 0.330 0.000
G45.4 Transient global amnesia
0.669 0.331 0.000
G47.3 Sleep apnoea
0.669 0.331 0.000
Y59 Other and unspecified vaccines and biological substances
0.669 0.331 0.000
Y58 Bacterial vaccines
0.669 0.331 0.000
Y57 Other and unspecified drugs and medicaments
0.669 0.331 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.669 0.331 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.669 0.331 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.669 0.331 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.669 0.331 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.669 0.331 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.669 0.331 0.000
Y48 Anaesthetics and therapeutic gases
0.669 0.331 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.669 0.331 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.669 0.331 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.669 0.331 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.668 0.332 0.000
D45 Polycythaemia vera
0.667 0.333 0.000
I67 Other cerebrovascular diseases
0.667 0.333 0.000
C15 Malignant neoplasm of oesophagus
0.666 0.334 0.000
J32 Chronic sinusitis
0.666 0.334 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.665 0.334 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.665 0.334 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.665 0.334 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.665 0.334 0.000
I12.0 Hypertensive renal disease with renal failure
0.664 0.336 0.000
D67 Hereditary factor IX deficiency
0.664 0.336 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.664 0.336 0.000
M80-M85 Disorders of bone density and structure
0.663 0.336 0.000
A02 Other Salmonella infections
0.663 0.337 0.000
H53-H54 Visual disturbances and blindness
0.662 0.337 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.662 0.337 0.000
N81 Female genital prolapse
0.662 0.338 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.662 0.338 0.000
N18.5 Chronic kidney disease, stage 5
0.662 0.338 0.000
N03 Chronic nephritic syndrome
0.662 0.338 0.000
Chapter V Mental and behavioural disorders
0.661 0.339 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.660 0.340 0.000
S88 Traumatic amputation of lower leg
0.659 0.341 0.000
S87 Crushing injury of lower leg
0.659 0.341 0.000
S85 Injury of blood vessels at lower leg level
0.659 0.341 0.000
S84 Injury of nerves at lower leg level
0.659 0.341 0.000
L71 Rosacea
0.658 0.341 0.000
J60-J70 Lung diseases due to external agents
0.658 0.342 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.658 0.342 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.657 0.343 0.000
H31.0 Chorioretinal scars
0.657 0.343 0.000
I25.1 Atherosclerotic heart disease
0.656 0.344 0.000
I15 Secondary hypertension
0.656 0.344 0.000
C92 Myeloid leukaemia
0.656 0.344 0.000
T90 Sequelae of injuries of head
0.656 0.344 0.000
S08 Traumatic amputation of part of head
0.656 0.344 0.000
S07 Crushing injury of head
0.656 0.344 0.000
S04 Injury of cranial nerves
0.656 0.344 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.656 0.344 0.000
G30-G32 Other degenerative diseases of the nervous system
0.656 0.344 0.000
B35 Dermatophytosis
0.655 0.345 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.655 0.345 0.000
L60 Nail disorders
0.655 0.345 0.000
D62 Acute posthaemorrhagic anaemia
0.654 0.346 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.654 0.346 0.000
C83.7 Burkitt's tumour
0.654 0.346 0.000
C83.6 Undifferentiated (diffuse)
0.654 0.346 0.000
C83.5 Lymphoblastic (diffuse)
0.654 0.346 0.000
C83.4 Immunoblastic (diffuse)
0.654 0.346 0.000
C83.2 Mixed small and large cell (diffuse)
0.654 0.346 0.000
C83.1 Small cleaved cell (diffuse)
0.654 0.346 0.000
H44 Disorders of globe
0.654 0.346 0.000
S06 Intracranial injury
0.653 0.347 0.000
E87.2 Acidosis
0.653 0.347 0.000
L75 Apocrine sweat disorders
0.653 0.347 0.000
L74 Eccrine sweat disorders
0.653 0.347 0.000
L70 Acne
0.653 0.347 0.000
L68 Hypertrichosis
0.653 0.347 0.000
L67 Hair colour and hair shaft abnormalities
0.653 0.347 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.653 0.347 0.000
L64 Androgenic alopecia
0.653 0.347 0.000
L63 Alopecia areata
0.653 0.347 0.000
L62 Nail disorders in diseases classified elsewhere
0.653 0.347 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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