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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116079955
log Bayes Factor = 12.0849
Chromosome 5   position 127,696,604  (GRCh37) Explore rs116079955 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.996 0.004 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
I25.2 Old myocardial infarction
0.990 0.010 0.000
Chapter II Neoplasms
0.985 0.015 0.000
Chapter VII Diseases of the eye and adnexa
0.983 0.017 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.983 0.017 0.000
J43 Emphysema
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
I60-I69 Cerebrovascular diseases
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
J43.9 Emphysema, unspecified
0.968 0.032 0.000
I30-I52 Other forms of heart disease
0.957 0.043 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.955 0.045 0.000
E10-E14 Diabetes mellitus
0.955 0.045 0.000
E70-E90 Metabolic disorders
0.954 0.046 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.952 0.048 0.000
I69 Sequelae of cerebrovascular disease
0.948 0.052 0.000
C79 Secondary malignant neoplasm of other sites
0.947 0.053 0.000
O60-O75 Complications of labour and delivery
0.945 0.055 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.945 0.055 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.934 0.066 0.000
Chapter XXI Factors influencing health status and contact with health services
0.931 0.069 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.928 0.072 0.000
M50-M54 Other dorsopathies
0.922 0.078 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.919 0.081 0.000
I34 Nonrheumatic mitral valve disorders
0.917 0.083 0.000
Chapter XX External causes of morbidity and mortality
0.916 0.084 0.000
H53-H54 Visual disturbances and blindness
0.915 0.085 0.000
C60-C63 Malignant neoplasms of male genital organs
0.903 0.097 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.900 0.099 0.000
I25.1 Atherosclerotic heart disease
0.900 0.100 0.000
M70-M79 Other soft tissue disorders
0.896 0.104 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.895 0.105 0.000
I51 Complications and ill-defined descriptions of heart disease
0.892 0.108 0.000
G90-G99 Other disorders of the nervous system
0.890 0.110 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.884 0.116 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.880 0.120 0.000
E86 Volume depletion
0.880 0.120 0.000
I21 Acute myocardial infarction
0.879 0.121 0.000
I10-I15 Hypertensive diseases
0.878 0.122 0.000
Z72 Problems related to lifestyle
0.875 0.125 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.875 0.125 0.000
I34.0 Mitral (valve) insufficiency
0.871 0.129 0.000
C64-C68 Malignant neoplasms of urinary tract
0.868 0.132 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.863 0.137 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.863 0.137 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.858 0.142 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.858 0.142 0.000
M72 Fibroblastic disorders
0.857 0.143 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.854 0.146 0.000
Z75 Problems related to medical facilities and other health care
0.853 0.147 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.846 0.154 0.000
I51.9 Heart disease, unspecified
0.845 0.155 0.000
E11 Non-insulin-dependent diabetes mellitus
0.844 0.156 0.000
H30-H36 Disorders of choroid and retina
0.842 0.158 0.000
M80-M85 Disorders of bone density and structure
0.840 0.160 0.000
D00-D09 In situ neoplasms
0.835 0.165 0.000
I77 Other disorders of arteries and arterioles
0.834 0.166 0.000
E00-E07 Disorders of thyroid gland
0.834 0.166 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.832 0.168 0.000
Z72.0 Tobacco use
0.832 0.168 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.832 0.168 0.000
C61 Malignant neoplasm of prostate
0.831 0.169 0.000
Chapter I Certain infectious and parasitic diseases
0.831 0.169 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.830 0.170 0.000
I47 Paroxysmal tachycardia
0.827 0.173 0.000
I42 Cardiomyopathy
0.825 0.175 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.825 0.175 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.822 0.178 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.820 0.180 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.820 0.180 0.000
E10 Insulin-dependent diabetes mellitus
0.818 0.182 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.816 0.184 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.814 0.186 0.000
J95-J99 Other diseases of the respiratory system
0.812 0.188 0.000
E14 Unspecified diabetes mellitus
0.812 0.188 0.000
J45 Asthma
0.810 0.190 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.808 0.192 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.806 0.194 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.805 0.195 0.000
H53 Visual disturbances
0.804 0.196 0.000
O63 Long labour
0.804 0.196 0.000
M15-M19 Arthrosis
0.803 0.197 0.000
H54 Blindness and low vision
0.800 0.200 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.800 0.200 0.000
E50-E64 Other nutritional deficiencies
0.799 0.200 0.000
I35 Nonrheumatic aortic valve disorders
0.799 0.201 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.799 0.201 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.799 0.201 0.000
C79.2 Secondary malignant neoplasm of skin
0.799 0.201 0.000
M54 Dorsalgia
0.798 0.202 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
I11 Hypertensive heart disease
0.794 0.206 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.794 0.206 0.000
O85-O92 Complications predominantly related to the puerperium
0.793 0.207 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.793 0.207 0.000
B35-B49 Mycoses
0.793 0.207 0.000
C50-C50 Malignant neoplasm of breast
0.793 0.207 0.000
I61 Intracerebral haemorrhage
0.793 0.207 0.000
G70-G73 Diseases of myoneural junction and muscle
0.792 0.208 0.000
V10-V19 Pedal cyclist injured in transport accident
0.791 0.209 0.000
E11.5 With peripheral circulatory complications
0.788 0.212 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.787 0.213 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.784 0.216 0.000
J40 Bronchitis, not specified as acute or chronic
0.782 0.218 0.000
Z34 Supervision of normal pregnancy
0.781 0.219 0.000
Z35 Supervision of high-risk pregnancy
0.781 0.219 0.000
M77 Other enthesopathies
0.780 0.220 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.779 0.221 0.000
M51 Other intervertebral disk disorders
0.777 0.223 0.000
I72 Other aneurysm
0.775 0.225 0.000
O48 Prolonged pregnancy
0.774 0.226 0.000
E40-E46 Malnutrition
0.774 0.226 0.000
I67 Other cerebrovascular diseases
0.774 0.226 0.000
E74 Other disorders of carbohydrate metabolism
0.771 0.229 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.770 0.230 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.770 0.230 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.769 0.231 0.000
M50 Cervical disk disorders
0.766 0.234 0.000
C15-C26 Malignant neoplasms of digestive organs
0.765 0.235 0.000
B37 Candidiasis
0.765 0.235 0.000
I95 Hypotension
0.764 0.236 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.763 0.237 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.762 0.238 0.000
I34.1 Mitral (valve) prolapse
0.761 0.239 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.760 0.240 0.000
E16 Other disorders of pancreatic internal secretion
0.759 0.241 0.000
I74 Arterial embolism and thrombosis
0.757 0.243 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.755 0.245 0.000
H55-H59 Other disorders of eye and adnexa
0.755 0.245 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.754 0.246 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.753 0.247 0.000
S00-S09 Injuries to the head
0.752 0.248 0.000
H33 Retinal detachments and breaks
0.752 0.248 0.000
O24 Diabetes mellitus in pregnancy
0.749 0.251 0.000
M05-M14 Inflammatory polyarthropathies
0.747 0.253 0.000
C79.6 Secondary malignant neoplasm of ovary
0.746 0.254 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.746 0.254 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.743 0.257 0.000
I24 Other acute ischaemic heart diseases
0.742 0.257 0.000
H53.2 Diplopia
0.742 0.258 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.742 0.258 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.741 0.259 0.000
I77.1 Stricture of artery
0.740 0.260 0.000
I27 Other pulmonary heart diseases
0.739 0.261 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.739 0.261 0.000
H02 Other disorders of eyelid
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.737 0.263 0.000
B37.0 Candidal stomatitis
0.736 0.264 0.000
O73 Retained placenta and membranes, without haemorrhage
0.736 0.264 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.735 0.265 0.000
O66 Other obstructed labour
0.734 0.266 0.000
G83 Other paralytic syndromes
0.733 0.267 0.000
M86-M90 Other osteopathies
0.731 0.269 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.731 0.269 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.731 0.269 0.000
H10-H13 Disorders of conjunctiva
0.730 0.270 0.000
Z32 Pregnancy examination and test
0.730 0.270 0.000
J42 Unspecified chronic bronchitis
0.729 0.270 0.000
H54.7 Unspecified visual loss
0.729 0.271 0.000
O36 Maternal care for other known or suspected foetal problems
0.728 0.272 0.000
I99 Other and unspecified disorders of circulatory system
0.728 0.272 0.000
M54.2 Cervicalgia
0.728 0.272 0.000
G81 Hemiplegia
0.727 0.272 0.000
S60-S69 Injuries to the wrist and hand
0.726 0.274 0.000
O42 Premature rupture of membranes
0.726 0.274 0.000
I21.4 Acute subendocardial myocardial infarction
0.726 0.274 0.000
O30 Multiple gestation
0.725 0.275 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.724 0.276 0.000
I70 Atherosclerosis
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.722 0.278 0.000
Y43 Primarily systemic agents
0.722 0.278 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.722 0.278 0.000
M84 Disorders of continuity of bone
0.721 0.279 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.720 0.280 0.000
I10 Essential (primary) hypertension
0.719 0.281 0.000
B95-B98 Bacterial, viral and other infectious agents
0.718 0.282 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.718 0.282 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O21 Excessive vomiting in pregnancy
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
I71 Aortic aneurysm and dissection
0.716 0.284 0.000
O71 Other obstetric trauma
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
C78.7 Secondary malignant neoplasm of liver
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
Z33 Pregnant state, incidental
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.714 0.286 0.000
I25.3 Aneurysm of heart
0.714 0.286 0.000
Z31 Procreative management
0.713 0.287 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.288 0.000
M80 Osteoporosis with pathological fracture
0.711 0.289 0.000
M16 Coxarthrosis [arthrosis of hip]
0.710 0.290 0.000
D04 Carcinoma in situ of skin
0.709 0.290 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.709 0.291 0.000
I21.9 Acute myocardial infarction, unspecified
0.707 0.292 0.000
I47.1 Supraventricular tachycardia
0.707 0.293 0.000
H53.8 Other visual disturbances
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
I31 Other diseases of pericardium
0.705 0.295 0.000
O47 False labour
0.705 0.295 0.000
C15 Malignant neoplasm of oesophagus
0.705 0.295 0.000
I62 Other nontraumatic intracranial haemorrhage
0.704 0.296 0.000
J43.8 Other emphysema
0.703 0.297 0.000
J43.2 Centrilobular emphysema
0.703 0.297 0.000
J43.1 Panlobular emphysema
0.703 0.297 0.000
J43.0 MacLeod's syndrome
0.703 0.297 0.000
J98 Other respiratory disorders
0.703 0.297 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.297 0.000
M91-M94 Chondropathies
0.702 0.298 0.000
M60-M63 Disorders of muscles
0.702 0.298 0.000
H25-H28 Disorders of lens
0.702 0.298 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.702 0.298 0.000
J60-J70 Lung diseases due to external agents
0.701 0.298 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.700 0.300 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.700 0.300 0.000
S00 Superficial injury of head
0.699 0.301 0.000
E20-E35 Disorders of other endocrine glands
0.698 0.302 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.698 0.302 0.000
H43-H45 Disorders of vitreous body and globe
0.698 0.302 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.697 0.303 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.697 0.303 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
G35 Multiple sclerosis
0.696 0.304 0.000
O40 Polyhydramnios
0.695 0.304 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.695 0.305 0.000
J47 Bronchiectasis
0.695 0.305 0.000
D09 Carcinoma in situ of other and unspecified sites
0.694 0.306 0.000
I78 Diseases of capillaries
0.694 0.306 0.000
S10-S19 Injuries to the neck
0.694 0.306 0.000
C62 Malignant neoplasm of testis
0.694 0.306 0.000
G30-G32 Other degenerative diseases of the nervous system
0.692 0.308 0.000
H20 Iridocyclitis
0.691 0.309 0.000
O63.1 Prolonged second stage (of labour)
0.690 0.310 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
E16.2 Hypoglycaemia, unspecified
0.687 0.313 0.000
Y57 Other and unspecified drugs and medicaments
0.687 0.313 0.000
H33.3 Retinal breaks without detachment
0.687 0.313 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.687 0.313 0.000
G95 Other diseases of spinal cord
0.686 0.314 0.000
I52 Other heart disorders in diseases classified elsewhere
0.686 0.314 0.000
I48 Atrial fibrillation and flutter
0.686 0.314 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.686 0.314 0.000
I41 Myocarditis in diseases classified elsewhere
0.686 0.314 0.000
I40 Acute myocarditis
0.686 0.314 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.686 0.314 0.000
I37 Pulmonary valve disorders
0.686 0.314 0.000
I36 Nonrheumatic tricuspid valve disorders
0.686 0.314 0.000
I32 Pericarditis in diseases classified elsewhere
0.686 0.314 0.000
I30 Acute pericarditis
0.686 0.314 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.686 0.314 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.685 0.314 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.685 0.315 0.000
E13 Other specified diabetes mellitus
0.685 0.315 0.000
E12 Malnutrition-related diabetes mellitus
0.685 0.315 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.684 0.316 0.000
E85 Amyloidosis
0.684 0.316 0.000
E84 Cystic fibrosis
0.684 0.316 0.000
E79 Disorders of purine and pyrimidine metabolism
0.684 0.316 0.000
E77 Disorders of glycoprotein metabolism
0.684 0.316 0.000
E76 Disorders of glycosaminoglycan metabolism
0.684 0.316 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.684 0.316 0.000
E73 Lactose intolerance
0.684 0.316 0.000
E72 Other disorders of amino-acid metabolism
0.684 0.316 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.684 0.316 0.000
E70 Disorders of aromatic amino-acid metabolism
0.684 0.316 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.684 0.316 0.000
Z73 Problems related to life-management difficulty
0.684 0.316 0.000
M18 Arthrosis of first carpometacarpal joint
0.684 0.316 0.000
C65 Malignant neoplasm of renal pelvis
0.684 0.316 0.000
Y52 Agents primarily affecting the cardiovascular system
0.683 0.317 0.000
Z74 Problems related to care-provider dependency
0.682 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.681 0.319 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.680 0.320 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.680 0.320 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.679 0.321 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.679 0.321 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.679 0.321 0.000
Z39 Postpartum care and examination
0.679 0.321 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.679 0.321 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.679 0.321 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.679 0.321 0.000
E89.0 Postprocedural hypothyroidism
0.679 0.321 0.000
I22 Subsequent myocardial infarction
0.678 0.322 0.000
M16.9 Coxarthrosis, unspecified
0.678 0.322 0.000
O74 Complications of anaesthesia during labour and delivery
0.678 0.322 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.678 0.322 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.678 0.322 0.000
O61 Failed induction of labour
0.678 0.322 0.000
O60 Preterm delivery
0.678 0.322 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.677 0.323 0.000
O46.9 Antepartum haemorrhage, unspecified
0.677 0.323 0.000
E05.9 Thyrotoxicosis, unspecified
0.677 0.323 0.000
Z35.5 Supervision of elderly primigravida
0.677 0.323 0.000
E87.7 Fluid overload
0.676 0.324 0.000
D05 Carcinoma in situ of breast
0.676 0.324 0.000
H35 Other retinal disorders
0.676 0.324 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.675 0.325 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.675 0.325 0.000
I20 Angina pectoris
0.674 0.326 0.000
Y86 Sequelae of other accidents
0.674 0.326 0.000
O72 Postpartum haemorrhage
0.674 0.326 0.000
I72.0 Aneurysm of carotid artery
0.672 0.328 0.000
J46 Status asthmaticus
0.672 0.328 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
Y85 Sequelae of transport accidents
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.670 0.330 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.670 0.330 0.000
O45 Premature separation of placenta [abruptio placentae]
0.670 0.330 0.000
O44 Placenta praevia
0.670 0.330 0.000
O43 Placental disorders
0.670 0.330 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.670 0.330 0.000
O33 Maternal care for known or suspected disproportion
0.670 0.330 0.000
O31 Complications specific to multiple gestation
0.670 0.330 0.000
E14.9 Without complications
0.669 0.331 0.000
I67.8 Other specified cerebrovascular diseases
0.669 0.331 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.669 0.331 0.000
I33 Acute and subacute endocarditis
0.668 0.332 0.000
I51.7 Cardiomegaly
0.667 0.333 0.000
G20-G26 Extrapyramidal and movement disorders
0.667 0.333 0.000
I69.3 Sequelae of cerebral infarction
0.667 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.667 0.333 0.000
G96 Other disorders of central nervous system
0.666 0.334 0.000
G70 Myasthenia gravis and other myoneural disorders
0.665 0.335 0.000
E11.4 With neurological complications
0.665 0.335 0.000
Z72.2 Drug use
0.665 0.335 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.664 0.336 0.000
B37.9 Candidiasis, unspecified
0.663 0.337 0.000
E83 Disorders of mineral metabolism
0.662 0.338 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.662 0.338 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.662 0.338 0.000
E11.2 With renal complications
0.661 0.339 0.000
M53 Other dorsopathies, not elsewhere classified
0.661 0.339 0.000
M51.4 Schmorl's nodes
0.660 0.340 0.000
E87.2 Acidosis
0.660 0.340 0.000
Z76 Persons encountering health services in other circumstances
0.659 0.341 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.659 0.341 0.000
Z72.1 Alcohol use
0.659 0.341 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.658 0.342 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.658 0.342 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.658 0.342 0.000
G93 Other disorders of brain
0.657 0.343 0.000
Y35-Y36 Legal intervention and operations of war
0.656 0.343 0.000
Y10-Y34 Event of undetermined intent
0.656 0.343 0.000
Y00-Y09 Assault
0.656 0.343 0.000
X85-X99 Assault
0.656 0.343 0.000
X50-X57 Overexertion, travel and privation
0.656 0.343 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.656 0.343 0.000
X30-X39 Exposure to forces of nature
0.656 0.343 0.000
X20-X29 Contact with venomous animals and plants
0.656 0.343 0.000
X10-X19 Contact with heat and hot substances
0.656 0.343 0.000
X00-X09 Exposure to smoke, fire and flames
0.656 0.343 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.656 0.343 0.000
W75-W84 Other accidental threats to breathing
0.656 0.343 0.000
W65-W74 Accidental drowning and submersion
0.656 0.343 0.000
W50-W64 Exposure to animate mechanical forces
0.656 0.343 0.000
V98-V99 Other and unspecified transport accidents
0.656 0.343 0.000
V95-V97 Air and space transport accidents
0.656 0.343 0.000
V90-V94 Water transport accidents
0.656 0.343 0.000
V80-V89 Other land transport accidents
0.656 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.656 0.343 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.656 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.656 0.343 0.000
V40-V49 Car occupant injured in transport accident
0.656 0.343 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.656 0.343 0.000
V01-V09 Pedestrian injured in transport accident
0.656 0.343 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.656 0.344 0.000
C50 Malignant neoplasm of breast
0.655 0.345 0.000
M54.22 Cervicalgia (Cervical region)
0.655 0.345 0.000
M54.9 Dorsalgia, unspecified
0.653 0.346 0.000
O75.8 Other specified complications of labour and delivery
0.653 0.347 0.000
E87.3 Alkalosis
0.653 0.347 0.000
M50.1 Cervical disk disorder with radiculopathy
0.652 0.348 0.000
J45.9 Asthma, unspecified
0.652 0.348 0.000
M77.9 Enthesopathy, unspecified
0.652 0.348 0.000
M06 Other rheumatoid arthritis
0.652 0.348 0.000
O36.9 Maternal care for foetal problem, unspecified
0.652 0.348 0.000
C71 Malignant neoplasm of brain
0.651 0.349 0.000
E53 Deficiency of other B group vitamins
0.651 0.349 0.000
O70 Perineal laceration during delivery
0.651 0.349 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.650 0.350 0.000
O86 Other puerperal infections
0.649 0.351 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.649 0.351 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.649 0.351 0.000
I27.0 Primary pulmonary hypertension
0.648 0.352 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.647 0.353 0.000
C60 Malignant neoplasm of penis
0.647 0.353 0.000
I35.8 Other aortic valve disorders
0.647 0.353 0.000
M45-M49 Spondylopathies
0.647 0.353 0.000
M77.1 Lateral epicondylitis
0.646 0.354 0.000
E14.3 With ophthalmic complications
0.646 0.354 0.000
I47.2 Ventricular tachycardia
0.645 0.354 0.000
H31 Other disorders of choroid
0.645 0.355 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.645 0.355 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.644 0.356 0.000
M76 Enthesopathies of lower limb, excluding foot
0.642 0.358 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.642 0.358 0.000
C78.0 Secondary malignant neoplasm of lung
0.642 0.358 0.000
O29 Complications of anaesthesia during pregnancy
0.642 0.358 0.000
O28 Abnormal findings on antenatal screening of mother
0.642 0.358 0.000
O23 Infections of genito-urinary tract in pregnancy
0.642 0.358 0.000
O22 Venous complications in pregnancy
0.642 0.358 0.000
O25 Malnutrition in pregnancy
0.642 0.358 0.000
M65-M68 Disorders of synovium and tendon
0.641 0.359 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.641 0.359 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.641 0.359 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.640 0.359 0.000
I51.5 Myocardial degeneration
0.640 0.360 0.000
I51.4 Myocarditis, unspecified
0.640 0.360 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.640 0.360 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.640 0.360 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.640 0.360 0.000
I51.0 Cardiac septal defect, acquired
0.640 0.360 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.639 0.360 0.000
E87.5 Hyperkalaemia
0.639 0.361 0.000
G83.4 Cauda equina syndrome
0.639 0.361 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.638 0.362 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.638 0.362 0.000
G90 Disorders of autonomic nervous system
0.638 0.362 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.638 0.362 0.000
G92 Toxic encephalopathy
0.638 0.362 0.000
M54.4 Lumbago with sciatica
0.638 0.362 0.000
H02.6 Xanthelasma of eyelid
0.638 0.362 0.000
I95.1 Orthostatic hypotension
0.638 0.362 0.000
S00.9 Superficial injury of head, part unspecified
0.637 0.363 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.636 0.363 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.635 0.365 0.000
E10.9 Without complications
0.635 0.365 0.000
E06 Thyroiditis
0.634 0.366 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.634 0.366 0.000
Z38 Liveborn infants according to place of birth
0.633 0.366 0.000
I35.9 Aortic valve disorder, unspecified
0.634 0.366 0.000
H00 Hordeolum and chalazion
0.633 0.367 0.000
S64 Injury of nerves at wrist and hand level
0.632 0.368 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.631 0.369 0.000
H02.8 Other specified disorders of eyelid
0.631 0.369 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.630 0.369 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.630 0.369 0.000
G81.9 Hemiplegia, unspecified
0.630 0.370 0.000
E10.2 With renal complications
0.630 0.370 0.000
O20 Haemorrhage in early pregnancy
0.630 0.370 0.000
H02.1 Ectropion of eyelid
0.629 0.371 0.000
I15 Secondary hypertension
0.629 0.371 0.000
I13 Hypertensive heart and renal disease
0.629 0.371 0.000
V20-V29 Motorcycle rider injured in transport accident
0.628 0.371 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.628 0.372 0.000
Y44 Agents primarily affecting blood constituents
0.628 0.372 0.000
I42.9 Cardiomyopathy, unspecified
0.627 0.373 0.000
Z72.9 Problem related to lifestyle, unspecified
0.627 0.373 0.000
Z72.8 Other problems related to lifestyle
0.627 0.373 0.000
Z72.6 Gambling and betting
0.627 0.373 0.000
Z72.5 High-risk sexual behaviour
0.627 0.373 0.000
Z72.4 Inappropriate diet and eating habits
0.627 0.373 0.000
Z72.3 Lack of physical exercise
0.627 0.373 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.627 0.373 0.000
E87.4 Mixed disorder of acid-base balance
0.627 0.373 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.626 0.374 0.000
I42.8 Other cardiomyopathies
0.626 0.374 0.000
S50-S59 Injuries to the elbow and forearm
0.625 0.375 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.623 0.377 0.000
C66 Malignant neoplasm of ureter
0.623 0.377 0.000
E10.4 With neurological complications
0.622 0.378 0.000
E88 Other metabolic disorders
0.621 0.379 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.620 0.380 0.000
T90 Sequelae of injuries of head
0.620 0.380 0.000
H16 Keratitis
0.620 0.380 0.000
Z32.1 Pregnancy confirmed
0.620 0.380 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.619 0.381 0.000
V18.0 Driver injured in nontraffic accident
0.619 0.381 0.000
M50.0 Cervical disk disorder with myelopathy
0.619 0.381 0.000
G80 Infantile cerebral palsy
0.619 0.381 0.000
E10.1 With ketoacidosis
0.618 0.382 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.616 0.384 0.000
J98.4 Other disorders of lung
0.616 0.384 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.616 0.384 0.000
E15 Nondiabetic hypoglycaemic coma
0.615 0.384 0.000
H02.0 Entropion and trichiasis of eyelid
0.615 0.385 0.000
E46 Unspecified protein-energy malnutrition
0.615 0.385 0.000
M72.9 Fibroblastic disorder, unspecified
0.614 0.385 0.000
M72.8 Other fibroblastic disorders
0.614 0.385 0.000
M72.6 Necrotizing fasciitis
0.614 0.385 0.000
M72.5 Fasciitis, not elsewhere classified
0.614 0.385 0.000
M72.4 Pseudosarcomatous fibromatosis
0.614 0.385 0.000
M72.3 Nodular fasciitis
0.614 0.385 0.000
M72.1 Knuckle pads
0.614 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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