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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116086868
log Bayes Factor = 14.4058
Chromosome 8   position 17,448,828  (GRCh37) Explore rs116086868 on Ensembl!
Variant rs116086868 is part of Cluster X0037

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
S00-S09 Injuries to the head
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.992 0.008 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
K22 Other diseases of oesophagus
0.987 0.013 0.000
M20-M25 Other joint disorders
0.985 0.015 0.000
K50-K52 Noninfective enteritis and colitis
0.984 0.016 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.984 0.016 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.983 0.017 0.000
K22.1 Ulcer of oesophagus
0.982 0.018 0.000
S09 Other and unspecified injuries of head
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
E70-E90 Metabolic disorders
0.975 0.025 0.000
E78.0 Pure hypercholesterolaemia
0.974 0.026 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.974 0.026 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.973 0.027 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.971 0.029 0.000
Chapter XIV Diseases of the genitourinary system
0.969 0.031 0.000
K31 Other diseases of stomach and duodenum
0.969 0.031 0.000
S09.9 Unspecified injury of head
0.966 0.034 0.000
I20 Angina pectoris
0.948 0.052 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.944 0.056 0.000
M23 Internal derangement of knee
0.943 0.057 0.000
N30-N39 Other diseases of urinary system
0.942 0.058 0.000
K52 Other non-infective gastro-enteritis and colitis
0.938 0.062 0.000
Z90.7 Acquired absence of genital organ(s)
0.937 0.063 0.000
M05-M14 Inflammatory polyarthropathies
0.934 0.066 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.926 0.074 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.924 0.076 0.000
S01 Open wound of head
0.924 0.076 0.000
K31.7 Polyp of stomach and duodenum
0.923 0.077 0.000
N32 Other disorders of bladder
0.921 0.079 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.917 0.083 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.915 0.085 0.000
Z90.5 Acquired absence of kidney
0.912 0.088 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.909 0.091 0.000
Z80 Family history of malignant neoplasm
0.907 0.093 0.000
S70-S79 Injuries to the hip and thigh
0.902 0.098 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.902 0.098 0.000
S40-S49 Injuries to the shoulder and upper arm
0.901 0.099 0.000
S02 Fracture of skull and facial bones
0.899 0.101 0.000
I10-I15 Hypertensive diseases
0.898 0.102 0.000
M35 Other systemic involvement of connective tissue
0.897 0.103 0.000
Z85 Personal history of malignant neoplasm
0.893 0.107 0.000
I60-I69 Cerebrovascular diseases
0.892 0.108 0.000
N10-N16 Renal tubulo-interstitial diseases
0.891 0.109 0.000
R06 Abnormalities of breathing
0.890 0.110 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.889 0.111 0.000
I20.9 Angina pectoris, unspecified
0.886 0.114 0.000
R10 Abdominal and pelvic pain
0.885 0.115 0.000
M45-M49 Spondylopathies
0.879 0.121 0.000
N32.8 Other specified disorders of bladder
0.876 0.124 0.000
I83 Varicose veins of lower extremities
0.873 0.127 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.873 0.127 0.000
Z95.1 Presence of aortocoronary bypass graft
0.871 0.129 0.000
S00 Superficial injury of head
0.871 0.129 0.000
M13 Other arthritis
0.869 0.131 0.000
R10.4 Other and unspecified abdominal pain
0.868 0.132 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.864 0.136 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.863 0.137 0.000
K50 Crohn's disease [regional enteritis]
0.862 0.138 0.000
K22.2 Oesophageal obstruction
0.861 0.139 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.861 0.139 0.000
K70-K77 Diseases of liver
0.858 0.142 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.856 0.144 0.000
S80-S89 Injuries to the knee and lower leg
0.856 0.144 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.855 0.145 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.853 0.147 0.000
S20-S29 Injuries to the thorax
0.853 0.147 0.000
K55-K64 Other diseases of intestines
0.851 0.149 0.000
I24 Other acute ischaemic heart diseases
0.848 0.152 0.000
S01.0 Open wound of scalp
0.844 0.156 0.000
K25 Gastric ulcer
0.841 0.159 0.000
I10 Essential (primary) hypertension
0.839 0.161 0.000
K51 Ulcerative colitis
0.837 0.163 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.837 0.163 0.000
Z80.3 Family history of malignant neoplasm of breast
0.833 0.167 0.000
K52.1 Toxic gastro-enteritis and colitis
0.833 0.167 0.000
Z97 Presence of other devices
0.831 0.169 0.000
Q60-Q64 Congenital malformations of the urinary system
0.831 0.169 0.000
M35.3 Polymyalgia rheumatica
0.831 0.169 0.000
M22 Disorders of patella
0.824 0.176 0.000
M13.9 Arthritis, unspecified
0.823 0.177 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.819 0.181 0.000
K31.8 Other specified diseases of stomach and duodenum
0.816 0.184 0.000
R06.0 Dyspnoea
0.816 0.184 0.000
Z94 Transplanted organ and tissue status
0.816 0.184 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.815 0.185 0.000
K60 Fissure and fistula of anal and rectal regions
0.814 0.186 0.000
W00-W19 Falls
0.810 0.190 0.000
M25 Other joint disorders, not elsewhere classified
0.810 0.190 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.806 0.194 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.806 0.194 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.805 0.195 0.000
S72 Fracture of femur
0.804 0.196 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.803 0.197 0.000
R02 Gangrene, not elsewhere classified
0.797 0.203 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.797 0.203 0.000
E50-E64 Other nutritional deficiencies
0.796 0.204 0.000
N13 Obstructive and reflux uropathy
0.795 0.205 0.000
K50.1 Crohn's disease of large intestine
0.795 0.205 0.000
I30-I52 Other forms of heart disease
0.795 0.205 0.000
I63 Cerebral infarction
0.792 0.208 0.000
R12 Heartburn
0.792 0.208 0.000
K22.7 Barrett's oesophagus
0.791 0.209 0.000
I25.2 Old myocardial infarction
0.787 0.213 0.000
S60-S69 Injuries to the wrist and hand
0.787 0.213 0.000
Chapter VII Diseases of the eye and adnexa
0.784 0.216 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.783 0.217 0.000
M65-M68 Disorders of synovium and tendon
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.780 0.220 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.777 0.223 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.775 0.225 0.000
N32.9 Bladder disorder, unspecified
0.774 0.226 0.000
R00 Abnormalities of heart beat
0.774 0.226 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.771 0.229 0.000
R06.4 Hyperventilation
0.771 0.229 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.770 0.230 0.000
R06.5 Mouth breathing
0.769 0.231 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.767 0.233 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.767 0.233 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.767 0.233 0.000
R15 Faecal incontinence
0.767 0.233 0.000
M34 Systemic sclerosis
0.764 0.235 0.000
T66-T78 Other and unspecified effects of external causes
0.763 0.237 0.000
K35-K38 Diseases of appendix
0.763 0.237 0.000
X50-X57 Overexertion, travel and privation
0.763 0.237 0.000
V10-V19 Pedal cyclist injured in transport accident
0.763 0.237 0.000
Q61 Cystic kidney disease
0.762 0.238 0.000
R87 Abnormal findings in specimens from female genital organs
0.760 0.240 0.000
I20.8 Other forms of angina pectoris
0.759 0.241 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.758 0.242 0.000
S02.3 Fracture of orbital floor
0.756 0.244 0.000
I05-I09 Chronic rheumatic heart diseases
0.756 0.244 0.000
N25-N29 Other disorders of kidney and ureter
0.755 0.244 0.000
S50-S59 Injuries to the elbow and forearm
0.755 0.245 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.754 0.246 0.000
N32.3 Diverticulum of bladder
0.753 0.247 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.751 0.249 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.751 0.249 0.000
W20-W49 Exposure to inanimate mechanical forces
0.751 0.249 0.000
Chapter I Certain infectious and parasitic diseases
0.751 0.249 0.000
R10.3 Pain localised to other parts of lower abdomen
0.750 0.250 0.000
S06 Intracranial injury
0.749 0.251 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.747 0.253 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.747 0.253 0.000
M23.8 Other internal derangements of knee
0.745 0.255 0.000
Z93 Artificial opening status
0.744 0.256 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.744 0.256 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.742 0.257 0.000
M06 Other rheumatoid arthritis
0.742 0.258 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.741 0.259 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.741 0.259 0.000
Y43 Primarily systemic agents
0.741 0.259 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.739 0.261 0.000
S00.9 Superficial injury of head, part unspecified
0.739 0.261 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.737 0.263 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.736 0.264 0.000
N00-N08 Glomerular diseases
0.736 0.264 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.736 0.264 0.000
I80 Phlebitis and thrombophlebitis
0.735 0.265 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.735 0.265 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.735 0.265 0.000
S72.0 Fracture of neck of femur
0.734 0.266 0.000
I87 Other disorders of veins
0.732 0.268 0.000
I24.8 Other forms of acute ischaemic heart disease
0.732 0.268 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.730 0.270 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.730 0.270 0.000
I25.5 Ischaemic cardiomyopathy
0.729 0.270 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.729 0.271 0.000
Chapter V Mental and behavioural disorders
0.729 0.271 0.000
S01.8 Open wound of other parts of head
0.729 0.271 0.000
N60-N64 Disorders of breast
0.729 0.271 0.000
I20.1 Angina pectoris with documented spasm
0.729 0.271 0.000
S01.1 Open wound of eyelid and periocular area
0.728 0.272 0.000
S42 Fracture of shoulder and upper arm
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.727 0.273 0.000
S02.4 Fracture of malar and maxillary bones
0.726 0.274 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.726 0.274 0.000
Chapter XXII Codes for special purposes
0.724 0.276 0.000
M05 Seropositive rheumatoid arthritis
0.723 0.277 0.000
M48 Other spondylopathies
0.723 0.277 0.000
K60.2 Anal fissure, unspecified
0.722 0.278 0.000
M24 Other specific joint derangements
0.721 0.279 0.000
K76 Other diseases of liver
0.719 0.281 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.718 0.282 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.718 0.282 0.000
S70 Superficial injury of hip and thigh
0.718 0.282 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.717 0.283 0.000
M23.3 Other meniscus derangements
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
S02.2 Fracture of nasal bones
0.717 0.283 0.000
Z94.0 Kidney transplant status
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.716 0.284 0.000
S07 Crushing injury of head
0.716 0.284 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
S04 Injury of cranial nerves
0.716 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.284 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.716 0.284 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.716 0.284 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.714 0.286 0.000
Z89 Acquired absence of limb
0.714 0.286 0.000
Z84 Family history of other conditions
0.714 0.286 0.000
Z81 Family history of mental and behavioural disorders
0.714 0.286 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.714 0.286 0.000
N73 Other female pelvic inflammatory diseases
0.713 0.287 0.000
M40-M43 Deforming dorsopathies
0.712 0.287 0.000
M46 Other inflammatory spondylopathies
0.712 0.288 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.711 0.289 0.000
Q50-Q56 Congenital malformations of genital organs
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.711 0.289 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
I25.3 Aneurysm of heart
0.711 0.289 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.711 0.289 0.000
K28 Gastrojejunal ulcer
0.711 0.289 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.711 0.289 0.000
I74 Arterial embolism and thrombosis
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.710 0.290 0.000
K51.8 Other ulcerative colitis
0.710 0.290 0.000
S81 Open wound of lower leg
0.709 0.291 0.000
R47-R49 Symptoms and signs involving speech and voice
0.709 0.291 0.000
Z90.3 Acquired absence of part of stomach
0.708 0.292 0.000
M22.4 Chondromalacia patellae
0.708 0.292 0.000
K22.5 Diverticulum of oesophagus, acquired
0.708 0.292 0.000
K22.3 Perforation of oesophagus
0.708 0.292 0.000
K22.0 Achalasia of cardia
0.708 0.292 0.000
M23.4 Loose body in knee
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
M33 Dermatopolymyositis
0.706 0.294 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
M31 Other necrotising vasculopathies
0.706 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.706 0.294 0.000
M21 Other acquired deformities of limbs
0.706 0.294 0.000
Z90.8 Acquired absence of other organs
0.706 0.294 0.000
Z90.0 Acquired absence of part of head and neck
0.706 0.294 0.000
S00.7 Multiple superficial injuries of head
0.706 0.294 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.705 0.295 0.000
E40-E46 Malnutrition
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.705 0.295 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.704 0.296 0.000
R00.2 Palpitations
0.702 0.298 0.000
S09.8 Other specified injuries of head
0.702 0.298 0.000
S09.7 Multiple injuries of head
0.702 0.298 0.000
S09.2 Traumatic rupture of ear drum
0.702 0.298 0.000
S09.1 Injury of muscle and tendon of head
0.702 0.298 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.702 0.298 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.700 0.299 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.700 0.300 0.000
K59 Other functional intestinal disorders
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
E88 Other metabolic disorders
0.699 0.301 0.000
E85 Amyloidosis
0.699 0.301 0.000
E84 Cystic fibrosis
0.699 0.301 0.000
E79 Disorders of purine and pyrimidine metabolism
0.699 0.301 0.000
E77 Disorders of glycoprotein metabolism
0.699 0.301 0.000
E76 Disorders of glycosaminoglycan metabolism
0.699 0.301 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.699 0.301 0.000
E74 Other disorders of carbohydrate metabolism
0.699 0.301 0.000
E73 Lactose intolerance
0.699 0.301 0.000
E72 Other disorders of amino-acid metabolism
0.699 0.301 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.699 0.301 0.000
E70 Disorders of aromatic amino-acid metabolism
0.699 0.301 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.699 0.301 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.698 0.302 0.000
K60.1 Chronic anal fissure
0.698 0.302 0.000
E78.8 Other disorders of lipoprotein metabolism
0.698 0.302 0.000
E78.6 Lipoprotein deficiency
0.698 0.302 0.000
E78.4 Other hyperlipidaemia
0.698 0.302 0.000
E78.3 Hyperchylomicronaemia
0.698 0.302 0.000
E78.2 Mixed hyperlipidaemia
0.698 0.302 0.000
E78.1 Pure hyperglyceridaemia
0.698 0.302 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.698 0.302 0.000
Z95.3 Presence of xenogenic heart valve
0.697 0.303 0.000
Z90.1 Acquired absence of breast(s)
0.697 0.303 0.000
Y40 Systemic antibiotics
0.697 0.303 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.696 0.304 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.696 0.304 0.000
K22.9 Disease of oesophagus, unspecified
0.695 0.305 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.695 0.305 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.695 0.305 0.000
K31.6 Fistula of stomach and duodenum
0.695 0.305 0.000
K31.5 Obstruction of duodenum
0.695 0.305 0.000
K31.4 Gastric diverticulum
0.695 0.305 0.000
K31.3 Pylorospasm, not elsewhere classified
0.695 0.305 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.695 0.305 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.695 0.305 0.000
K31.0 Acute dilatation of stomach
0.695 0.305 0.000
K26 Duodenal ulcer
0.695 0.305 0.000
I63.9 Cerebral infarction, unspecified
0.694 0.306 0.000
E10-E14 Diabetes mellitus
0.693 0.307 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.693 0.307 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.693 0.307 0.000
I82 Other venous embolism and thrombosis
0.693 0.307 0.000
R87.6 Abnormal cytological findings
0.691 0.309 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.690 0.309 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.689 0.311 0.000
R50-R69 General symptoms and signs
0.689 0.311 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.688 0.312 0.000
I72 Other aneurysm
0.688 0.312 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.688 0.312 0.000
M11 Other crystal arthropathies
0.687 0.313 0.000
N32.0 Bladder-neck obstruction
0.687 0.313 0.000
I71 Aortic aneurysm and dissection
0.687 0.313 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.687 0.313 0.000
R18 Ascites
0.686 0.314 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.686 0.314 0.000
Y95 Nosocomial condition
0.685 0.315 0.000
I78 Diseases of capillaries
0.685 0.315 0.000
Z99.3 Dependence on wheelchair
0.685 0.315 0.000
I20.0 Unstable angina
0.684 0.316 0.000
S72.00 Fracture of neck of femur (closed)
0.684 0.316 0.000
Z99.1 Dependence on respirator
0.684 0.316 0.000
N36 Other disorders of urethra
0.684 0.316 0.000
M80-M85 Disorders of bone density and structure
0.681 0.319 0.000
K60.3 Anal fistula
0.680 0.320 0.000
E00-E07 Disorders of thyroid gland
0.679 0.321 0.000
M25.4 Effusion of joint
0.679 0.321 0.000
M47 Spondylosis
0.679 0.321 0.000
I45 Other conduction disorders
0.679 0.321 0.000
K70 Alcoholic liver disease
0.677 0.323 0.000
M23.9 Internal derangement of knee, unspecified
0.676 0.324 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.676 0.324 0.000
M23.5 Chronic instability of knee
0.676 0.324 0.000
M23.1 Discoid meniscus (congenital)
0.676 0.324 0.000
M23.0 Cystic meniscus
0.676 0.324 0.000
Z99.2 Dependence on renal dialysis
0.676 0.324 0.000
N37 Urethral disorders in diseases classified elsewhere
0.675 0.324 0.000
N34 Urethritis and urethral syndrome
0.675 0.324 0.000
N33 Bladder disorders in diseases classified elsewhere
0.675 0.324 0.000
E20-E35 Disorders of other endocrine glands
0.675 0.325 0.000
I25.1 Atherosclerotic heart disease
0.675 0.325 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.674 0.326 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.673 0.327 0.000
K52.3 Indeterminate colitis
0.673 0.327 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.673 0.327 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.673 0.327 0.000
Z95.0 Presence of cardiac pacemaker
0.672 0.328 0.000
I47 Paroxysmal tachycardia
0.671 0.329 0.000
M14 Arthropathies in other diseases classified elsewhere
0.669 0.331 0.000
M12 Other specific arthropathies
0.669 0.331 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.669 0.331 0.000
M08 Juvenile arthritis
0.669 0.331 0.000
M07 Psoriatic and enteropathic arthropathies
0.669 0.331 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.669 0.331 0.000
H25-H28 Disorders of lens
0.669 0.331 0.000
Q61.3 Polycystic kidney, unspecified
0.668 0.332 0.000
K27 Peptic ulcer, site unspecified
0.666 0.334 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.666 0.334 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.664 0.336 0.000
Q80-Q89 Other congenital malformations
0.664 0.336 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.664 0.336 0.000
Q35-Q37 Cleft lip and cleft palate
0.664 0.336 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.664 0.336 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.664 0.336 0.000
Q00-Q07 Congenital malformations of the nervous system
0.664 0.336 0.000
I88 Nonspecific lymphadenitis
0.662 0.337 0.000
I86 Varicose veins of other sites
0.662 0.337 0.000
I81 Portal vein thrombosis
0.662 0.337 0.000
S01.7 Multiple open wounds of head
0.662 0.338 0.000
S01.4 Open wound of cheek and temporomandibular area
0.662 0.338 0.000
S01.3 Open wound of ear
0.662 0.338 0.000
S01.2 Open wound of nose
0.662 0.338 0.000
N32.4 Rupture of bladder, nontraumatic
0.661 0.339 0.000
N32.2 Vesical fistula, not elsewhere classified
0.661 0.339 0.000
N32.1 Vesicointestinal fistula
0.661 0.339 0.000
R55 Syncope and collapse
0.659 0.341 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.658 0.342 0.000
Z97.4 Presence of external hearing-aid
0.658 0.342 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.658 0.342 0.000
M35.0 Sicca syndrome [Sjogren]
0.656 0.343 0.000
S89 Other and unspecified injuries of lower leg
0.656 0.344 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.656 0.344 0.000
W07 Fall involving chair
0.655 0.345 0.000
S02.30 Fracture of orbital floor (closed)
0.654 0.346 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.653 0.347 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.652 0.348 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.652 0.348 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.652 0.348 0.000
K22.4 Dyskinesia of oesophagus
0.651 0.349 0.000
E61 Deficiency of other nutrient elements
0.651 0.349 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.651 0.349 0.000
Z80.6 Family history of leukaemia
0.651 0.349 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.651 0.349 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.651 0.349 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.650 0.350 0.000
Q61.2 Polycystic kidney, adult type
0.650 0.350 0.000
K51.2 Ulcerative (chronic) proctitis
0.650 0.350 0.000
Z93.1 Gastrostomy status
0.649 0.351 0.000
R06.2 Wheezing
0.649 0.351 0.000
N13.4 Hydroureter
0.649 0.351 0.000
S69 Other and unspecified injuries of wrist and hand
0.648 0.352 0.000
N70 Salpingitis and oophoritis
0.647 0.353 0.000
K65-K67 Diseases of peritoneum
0.647 0.353 0.000
S79 Other and unspecified injuries of hip and thigh
0.646 0.353 0.000
S78 Traumatic amputation of hip and thigh
0.646 0.353 0.000
S77 Crushing injury of hip and thigh
0.646 0.353 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.646 0.353 0.000
S75 Injury of blood vessels at hip and thigh level
0.646 0.353 0.000
S74 Injury of nerves at hip and thigh level
0.646 0.353 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.646 0.353 0.000
S71 Open wound of hip and thigh
0.646 0.353 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.647 0.353 0.000
W13 Fall from, out of or through building or structure
0.646 0.353 0.000
R01 Cardiac murmurs and other cardiac sounds
0.646 0.354 0.000
R17 Unspecified jaundice
0.646 0.354 0.000
S48 Traumatic amputation of shoulder and upper arm
0.646 0.354 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.646 0.354 0.000
S44 Injury of nerves at shoulder and upper arm level
0.646 0.354 0.000
S41 Open wound of shoulder and upper arm
0.646 0.354 0.000
S40 Superficial injury of shoulder and upper arm
0.646 0.354 0.000
S47 Crushing injury of shoulder and upper arm
0.646 0.354 0.000
K22.8 Other specified diseases of oesophagus
0.645 0.354 0.000
R10.2 Pelvic and perineal pain
0.645 0.355 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.645 0.355 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.645 0.355 0.000
S02.8 Fractures of other skull and facial bones
0.645 0.355 0.000
S02.7 Multiple fractures involving skull and facial bones
0.645 0.355 0.000
S02.6 Fracture of mandible
0.645 0.355 0.000
S02.5 Fracture of tooth
0.645 0.355 0.000
S02.0 Fracture of vault of skull
0.645 0.355 0.000
I31 Other diseases of pericardium
0.644 0.355 0.000
I15 Secondary hypertension
0.644 0.356 0.000
I13 Hypertensive heart and renal disease
0.644 0.356 0.000
I11 Hypertensive heart disease
0.644 0.356 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.643 0.357 0.000
M35.8 Other specified systemic involvement of connective tissue
0.643 0.357 0.000
M35.7 Hypermobility syndrome
0.643 0.357 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.643 0.357 0.000
M35.5 Multifocal fibrosclerosis
0.643 0.357 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.643 0.357 0.000
M35.2 Behcet's disease
0.643 0.357 0.000
M35.1 Other overlap syndromes
0.643 0.357 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.641 0.359 0.000
S80 Superficial injury of lower leg
0.641 0.359 0.000
K75 Other inflammatory liver diseases
0.641 0.359 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.641 0.359 0.000
S01.9 Open wound of head, part unspecified
0.640 0.360 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.640 0.360 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.640 0.360 0.000
M13.98 Arthritis, unspecified (Other)
0.639 0.361 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.639 0.361 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.638 0.361 0.000
N15 Other renal tubulo-interstitial diseases
0.638 0.361 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.638 0.361 0.000
N11 Chronic tubulo-interstitial nephritis
0.638 0.361 0.000
N10 Acute tubulo-interstitial nephritis
0.638 0.361 0.000
R06.7 Sneezing
0.638 0.362 0.000
R06.6 Hiccough
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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