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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116161699
log Bayes Factor = 8.96181
Chromosome 6   position 66,726,604  (GRCh37) Explore rs116161699 on Ensembl!
Variant rs116161699 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.981 0.019 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Chapter I Certain infectious and parasitic diseases
0.971 0.029 0.000
M65-M68 Disorders of synovium and tendon
0.962 0.038 0.000
Chapter IX Diseases of the circulatory system
0.956 0.044 0.000
Chapter XXI Factors influencing health status and contact with health services
0.956 0.044 0.000
M05-M14 Inflammatory polyarthropathies
0.951 0.049 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.950 0.050 0.000
S50-S59 Injuries to the elbow and forearm
0.949 0.051 0.000
M65 Synovitis and tenosynovitis
0.948 0.052 0.000
B95-B98 Bacterial, viral and other infectious agents
0.947 0.053 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.944 0.056 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.944 0.056 0.000
I60-I69 Cerebrovascular diseases
0.942 0.058 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.937 0.063 0.000
T81 Complications of procedures, not elsewhere classified
0.932 0.068 0.000
M65.3 Trigger finger
0.932 0.068 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.931 0.069 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.927 0.073 0.000
T93 Sequelae of injuries of lower limb
0.926 0.074 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.924 0.076 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.923 0.077 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.921 0.079 0.000
L20-L30 Dermatitis and eczema
0.920 0.080 0.000
M65.34 Trigger finger-Hand
0.920 0.080 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.920 0.080 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.912 0.088 0.000
S90-S99 Injuries to the ankle and foot
0.908 0.092 0.000
G35 Multiple sclerosis
0.903 0.097 0.000
Y86 Sequelae of other accidents
0.901 0.099 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.900 0.100 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.898 0.102 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.898 0.102 0.000
M20-M25 Other joint disorders
0.896 0.104 0.000
M13 Other arthritis
0.886 0.114 0.000
G82 Paraplegia and tetraplegia
0.877 0.123 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.871 0.129 0.000
I77 Other disorders of arteries and arterioles
0.870 0.130 0.000
S00-S09 Injuries to the head
0.870 0.130 0.000
Z13 Special screening examination for other diseases and disorders
0.868 0.132 0.000
I63 Cerebral infarction
0.867 0.133 0.000
Chapter VII Diseases of the eye and adnexa
0.864 0.136 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.862 0.138 0.000
M86-M90 Other osteopathies
0.856 0.143 0.000
S60-S69 Injuries to the wrist and hand
0.850 0.150 0.000
S50 Superficial injury of forearm
0.846 0.154 0.000
L91 Hypertrophic disorders of skin
0.846 0.154 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.845 0.155 0.000
Z72 Problems related to lifestyle
0.844 0.156 0.000
T91 Sequelae of injuries of neck and trunk
0.840 0.160 0.000
I67 Other cerebrovascular diseases
0.839 0.161 0.000
M24 Other specific joint derangements
0.838 0.162 0.000
S70-S79 Injuries to the hip and thigh
0.838 0.162 0.000
G81 Hemiplegia
0.837 0.163 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.835 0.165 0.000
T92 Sequelae of injuries of upper limb
0.834 0.166 0.000
M13.9 Arthritis, unspecified
0.832 0.168 0.000
Z72.1 Alcohol use
0.830 0.170 0.000
S59 Other and unspecified injuries of forearm
0.829 0.171 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.828 0.172 0.000
L60-L75 Disorders of skin appendages
0.828 0.172 0.000
B35-B49 Mycoses
0.828 0.172 0.000
Z04 Examination and observation for other reasons
0.826 0.174 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.825 0.175 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.824 0.176 0.000
I77.6 Arteritis, unspecified
0.822 0.178 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.822 0.178 0.000
I69 Sequelae of cerebrovascular disease
0.821 0.179 0.000
I60 Subarachnoid haemorrhage
0.819 0.181 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.817 0.183 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.816 0.184 0.000
L30 Other dermatitis
0.816 0.184 0.000
Z13.9 Special screening examination, unspecified
0.815 0.185 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.812 0.187 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.812 0.188 0.000
M05 Seropositive rheumatoid arthritis
0.812 0.188 0.000
T42.4 Benzodiazepines
0.808 0.192 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.804 0.196 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.802 0.198 0.000
I63.8 Other cerebral infarction
0.802 0.198 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.801 0.199 0.000
S20-S29 Injuries to the thorax
0.801 0.199 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.799 0.201 0.000
S01 Open wound of head
0.799 0.201 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.798 0.202 0.000
Y95 Nosocomial condition
0.797 0.203 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.797 0.203 0.000
G40-G47 Episodic and paroxysmal disorders
0.795 0.205 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.793 0.207 0.000
L82 Seborrhoeic keratosis
0.792 0.208 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.792 0.208 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.789 0.211 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.787 0.213 0.000
G40 Epilepsy
0.786 0.214 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.786 0.214 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.783 0.217 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
S90 Superficial injury of ankle and foot
0.778 0.222 0.000
T43.6 Psychostimulants with abuse potential
0.778 0.222 0.000
L90 Atrophic disorders of skin
0.777 0.223 0.000
Z57 Occupational exposure to risk-factors
0.776 0.224 0.000
T93.2 Sequelae of other fractures of lower limb
0.776 0.224 0.000
M07 Psoriatic and enteropathic arthropathies
0.776 0.224 0.000
L91.8 Other hypertrophic disorders of skin
0.774 0.226 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.773 0.227 0.000
L50-L54 Urticaria and erythema
0.773 0.227 0.000
V40-V49 Car occupant injured in transport accident
0.772 0.228 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.772 0.228 0.000
S50.9 Superficial injury of forearm, unspecified
0.772 0.228 0.000
Q80-Q89 Other congenital malformations
0.772 0.228 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.772 0.228 0.000
L60 Nail disorders
0.769 0.231 0.000
H53-H54 Visual disturbances and blindness
0.769 0.231 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.768 0.232 0.000
I05-I09 Chronic rheumatic heart diseases
0.768 0.232 0.000
B50-B64 Protozoal diseases
0.767 0.233 0.000
M00-M03 Infectious arthropathies
0.767 0.233 0.000
L29 Pruritus
0.766 0.234 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.766 0.234 0.000
I72 Other aneurysm
0.766 0.234 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.765 0.235 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.765 0.235 0.000
T81.9 Unspecified complication of procedure
0.765 0.235 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.765 0.235 0.000
Z04.3 Examination and observation following other accident
0.763 0.237 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.761 0.239 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.761 0.239 0.000
G81.9 Hemiplegia, unspecified
0.760 0.240 0.000
S40-S49 Injuries to the shoulder and upper arm
0.758 0.242 0.000
B65-B83 Helminthiases
0.758 0.242 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.757 0.243 0.000
M24.1 Other articular cartilage disorders
0.756 0.244 0.000
S01.0 Open wound of scalp
0.755 0.245 0.000
Y43 Primarily systemic agents
0.755 0.245 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.754 0.246 0.000
T43.2 Other and unspecified antidepressants
0.753 0.247 0.000
G82.1 Spastic paraplegia
0.753 0.247 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.753 0.247 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.752 0.248 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.752 0.248 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.749 0.250 0.000
Z75 Problems related to medical facilities and other health care
0.746 0.254 0.000
L28 Lichen simplex chronicus and prurigo
0.746 0.254 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.744 0.256 0.000
S59.9 Unspecified injury of forearm
0.742 0.258 0.000
W50-W64 Exposure to animate mechanical forces
0.742 0.258 0.000
T42.1 Iminostilbenes
0.742 0.258 0.000
G83 Other paralytic syndromes
0.742 0.258 0.000
M60-M63 Disorders of muscles
0.741 0.259 0.000
I71 Aortic aneurysm and dissection
0.740 0.260 0.000
L23 Allergic contact dermatitis
0.740 0.260 0.000
T00-T07 Injuries involving multiple body regions
0.740 0.260 0.000
G82.4 Spastic tetraplegia
0.738 0.262 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.738 0.262 0.000
T90 Sequelae of injuries of head
0.736 0.264 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.736 0.264 0.000
L60.0 Ingrowing nail
0.734 0.266 0.000
S52 Fracture of forearm
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.726 0.274 0.000
M31 Other necrotising vasculopathies
0.726 0.274 0.000
L30.9 Dermatitis, unspecified
0.725 0.275 0.000
S02 Fracture of skull and facial bones
0.724 0.276 0.000
H43-H45 Disorders of vitreous body and globe
0.722 0.278 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.722 0.278 0.000
Z76 Persons encountering health services in other circumstances
0.721 0.279 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.720 0.280 0.000
W00-W19 Falls
0.720 0.280 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.719 0.281 0.000
Chapter VIII Diseases of the ear and mastoid process
0.719 0.281 0.000
Z13.5 Special screening examination for eye and ear disorders
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.717 0.283 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.716 0.284 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.716 0.284 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.716 0.284 0.000
S92 Fracture of foot, except ankle
0.714 0.286 0.000
Q60-Q64 Congenital malformations of the urinary system
0.714 0.286 0.000
Z56 Problems related to employment and unemployment
0.713 0.287 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.712 0.288 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
M89 Other disorders of bone
0.710 0.290 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.290 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.710 0.290 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.290 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
G63.2 Diabetic polyneuropathy
0.710 0.290 0.000
S20 Superficial injury of thorax
0.707 0.292 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.707 0.293 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.293 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.707 0.293 0.000
B37 Candidiasis
0.706 0.294 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.705 0.295 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.705 0.295 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
G82.2 Paraplegia, unspecified
0.705 0.295 0.000
T98 Sequelae of other and unspecified effects of external causes
0.704 0.296 0.000
T95 Sequelae of burns, corrosions and frostbite
0.704 0.296 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.704 0.296 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.704 0.296 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.704 0.296 0.000
Z57.2 Occupational exposure to dust
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
D80-D89 Certain disorders involving the immune mechanism
0.703 0.297 0.000
H53 Visual disturbances
0.703 0.297 0.000
Q00-Q07 Congenital malformations of the nervous system
0.702 0.298 0.000
L10-L14 Bullous disorders
0.702 0.298 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.701 0.299 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.700 0.300 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.700 0.300 0.000
Y89 Sequelae of other external causes
0.699 0.301 0.000
L71 Rosacea
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.698 0.301 0.000
M21 Other acquired deformities of limbs
0.698 0.302 0.000
S69 Other and unspecified injuries of wrist and hand
0.697 0.303 0.000
M65.8 Other synovitis and tenosynovitis
0.697 0.303 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.696 0.304 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.696 0.304 0.000
A75-A79 Rickettsioses
0.696 0.304 0.000
A70-A74 Other diseases caused by chlamydiae
0.696 0.304 0.000
A65-A69 Other spirochaetal diseases
0.696 0.304 0.000
A20-A28 Certain zoonotic bacterial diseases
0.696 0.304 0.000
A15-A19 Tuberculosis
0.696 0.304 0.000
I77.1 Stricture of artery
0.695 0.305 0.000
S60 Superficial injury of wrist and hand
0.694 0.306 0.000
I77.0 Arteriovenous fistula, acquired
0.693 0.306 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.693 0.307 0.000
S91 Open wound of ankle and foot
0.693 0.307 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.691 0.309 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.690 0.310 0.000
M66 Spontaneous rupture of synovium and tendon
0.690 0.310 0.000
T93.1 Sequelae of fracture of femur
0.690 0.310 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.689 0.311 0.000
S51 Open wound of forearm
0.688 0.312 0.000
A00-A09 Intestinal infectious diseases
0.688 0.312 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.687 0.312 0.000
L84 Corns and callosities
0.687 0.313 0.000
L90.0 Lichen sclerosus et atrophicus
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
I00-I02 Acute rheumatic fever
0.686 0.314 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.314 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
M90 Osteopathies in diseases classified elsewhere
0.684 0.316 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.684 0.316 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.683 0.317 0.000
T91.1 Sequelae of fracture of spine
0.682 0.318 0.000
T86 Failure and rejection of transplanted organs and tissues
0.682 0.318 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
M12 Other specific arthropathies
0.682 0.318 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.682 0.318 0.000
M08 Juvenile arthritis
0.682 0.318 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.682 0.318 0.000
L81 Other disorders of pigmentation
0.681 0.319 0.000
S58 Traumatic amputation of forearm
0.681 0.319 0.000
S57 Crushing injury of forearm
0.681 0.319 0.000
S56 Injury of muscle and tendon at forearm level
0.681 0.319 0.000
S55 Injury of blood vessels at forearm level
0.681 0.319 0.000
S54 Injury of nerves at forearm level
0.681 0.319 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.681 0.319 0.000
I72.8 Aneurysm of other specified arteries
0.680 0.320 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.680 0.320 0.000
M65.2 Calcific tendinitis
0.680 0.320 0.000
M65.1 Other infective (teno)synovitis
0.680 0.320 0.000
M65.0 Abscess of tendon sheath
0.680 0.320 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.680 0.320 0.000
S68 Traumatic amputation of wrist and hand
0.678 0.322 0.000
I08 Multiple valve diseases
0.678 0.322 0.000
I30-I52 Other forms of heart disease
0.676 0.324 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.676 0.324 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.675 0.325 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.675 0.325 0.000
Y43.3 Other antineoplastic drugs
0.675 0.325 0.000
M70-M79 Other soft tissue disorders
0.674 0.326 0.000
H10-H13 Disorders of conjunctiva
0.674 0.326 0.000
T66-T78 Other and unspecified effects of external causes
0.673 0.327 0.000
M13.0 Polyarthritis, unspecified
0.672 0.328 0.000
Y88 Sequelae of surgical and medical care as external cause
0.672 0.328 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.672 0.328 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.672 0.328 0.000
L91.0 Keloid scar
0.672 0.328 0.000
I67.8 Other specified cerebrovascular diseases
0.671 0.329 0.000
S70 Superficial injury of hip and thigh
0.671 0.329 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.670 0.330 0.000
I67.9 Cerebrovascular disease, unspecified
0.669 0.331 0.000
S05 Injury of eye and orbit
0.669 0.331 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.669 0.331 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.668 0.332 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.668 0.332 0.000
Y85 Sequelae of transport accidents
0.668 0.332 0.000
M65.39 Trigger finger-Site unspec
0.668 0.332 0.000
M65.38 Trigger finger-Other
0.668 0.332 0.000
M65.37 Trigger finger-Ankle/foot
0.668 0.332 0.000
M65.36 Trigger finger-Lower leg
0.668 0.332 0.000
M65.35 Trigger finger-Pelvic/thigh
0.668 0.332 0.000
M65.33 Trigger finger-Forearm
0.668 0.332 0.000
M65.32 Trigger finger-Upper arm
0.668 0.332 0.000
M65.31 Trigger finger-Shldr region
0.668 0.332 0.000
M65.30 Trigger finger-Mult sites
0.668 0.332 0.000
L40-L45 Papulosquamous disorders
0.668 0.332 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.668 0.332 0.000
T43.9 Psychotropic drug, unspecified
0.668 0.332 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.668 0.332 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.668 0.332 0.000
S01.1 Open wound of eyelid and periocular area
0.667 0.333 0.000
G36 Other acute disseminated demyelination
0.666 0.334 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.666 0.334 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.665 0.335 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.665 0.335 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.665 0.335 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.664 0.336 0.000
Q35-Q37 Cleft lip and cleft palate
0.664 0.336 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.664 0.336 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.664 0.336 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.664 0.336 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.664 0.336 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.664 0.336 0.000
T93.0 Sequelae of open wound of lower limb
0.664 0.336 0.000
E00-E07 Disorders of thyroid gland
0.663 0.337 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.663 0.337 0.000
Z74 Problems related to care-provider dependency
0.662 0.338 0.000
G40.9 Epilepsy, unspecified
0.662 0.338 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.662 0.338 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.662 0.338 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.662 0.338 0.000
T42.3 Barbiturates
0.662 0.338 0.000
T42.2 Succinimides and oxazolidinediones
0.662 0.338 0.000
T42.0 Hydantoin derivatives
0.662 0.338 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.662 0.338 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.661 0.339 0.000
M10 Gout
0.661 0.339 0.000
Z10 Routine general health check-up of defined subpopulation
0.660 0.340 0.000
H55-H59 Other disorders of eye and adnexa
0.660 0.340 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.660 0.340 0.000
L25 Unspecified contact dermatitis
0.660 0.340 0.000
L24 Irritant contact dermatitis
0.660 0.340 0.000
L21 Seborrhoeic dermatitis
0.660 0.340 0.000
L20 Atopic dermatitis
0.660 0.340 0.000
L26 Exfoliative dermatitis
0.660 0.340 0.000
L22 Diaper [napkin] dermatitis
0.660 0.340 0.000
S99 Other and unspecified injuries of ankle and foot
0.659 0.340 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.659 0.341 0.000
L94 Other localised connective tissue disorders
0.659 0.341 0.000
L93 Lupus erythematosus
0.659 0.341 0.000
L87 Transepidermal elimination disorders
0.659 0.341 0.000
L88 Pyoderma gangrenosum
0.659 0.341 0.000
L86 Keratoderma in diseases classified elsewhere
0.659 0.341 0.000
L80 Vitiligo
0.659 0.341 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.659 0.341 0.000
G80 Infantile cerebral palsy
0.658 0.342 0.000
T13 Other injuries of lower limb, level unspecified
0.657 0.343 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.656 0.344 0.000
M35 Other systemic involvement of connective tissue
0.654 0.345 0.000
I77.8 Other specified disorders of arteries and arterioles
0.654 0.346 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.654 0.346 0.000
I67.2 Cerebral atherosclerosis
0.654 0.346 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.653 0.346 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.654 0.346 0.000
T21 Burn and corrosion of trunk
0.653 0.347 0.000
T23 Burn and corrosion of wrist and hand
0.652 0.348 0.000
T91.3 Sequelae of injury of spinal cord
0.652 0.348 0.000
Y44 Agents primarily affecting blood constituents
0.652 0.348 0.000
M87 Osteonecrosis
0.651 0.349 0.000
S98 Traumatic amputation of ankle and foot
0.651 0.349 0.000
S97 Crushing injury of ankle and foot
0.651 0.349 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.651 0.349 0.000
S95 Injury of blood vessels at ankle and foot level
0.651 0.349 0.000
S94 Injury of nerves at ankle and foot level
0.651 0.349 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.650 0.349 0.000
M07.3 Other psoriatic arthropathies
0.650 0.350 0.000
S72 Fracture of femur
0.650 0.350 0.000
I61 Intracerebral haemorrhage
0.649 0.351 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.648 0.352 0.000
B25-B34 Other viral diseases
0.648 0.352 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.648 0.352 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.647 0.353 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.646 0.354 0.000
I62 Other nontraumatic intracranial haemorrhage
0.646 0.354 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.645 0.354 0.000
S37 Injury of urinary and pelvic organs
0.645 0.354 0.000
S36 Injury of intra-abdominal organs
0.645 0.354 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.645 0.354 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.645 0.354 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.645 0.354 0.000
S31 Open wound of abdomen, lower back and pelvis
0.645 0.354 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.645 0.354 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.645 0.355 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.645 0.355 0.000
H53.8 Other visual disturbances
0.644 0.356 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.644 0.356 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.644 0.356 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.644 0.356 0.000
G40.8 Other epilepsy
0.644 0.356 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.644 0.356 0.000
S06 Intracranial injury
0.644 0.356 0.000
B15-B19 Viral hepatitis
0.643 0.356 0.000
L50 Urticaria
0.643 0.357 0.000
Q85 Phakomatoses, not elsewhere classified
0.643 0.357 0.000
T31 Burns classified according to extent of body surface involved
0.643 0.357 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.642 0.358 0.000
M33 Dermatopolymyositis
0.642 0.358 0.000
M32 Systemic lupus erythematosus
0.642 0.358 0.000
M24.2 Disorder of ligament
0.641 0.359 0.000
S01.2 Open wound of nose
0.640 0.360 0.000
I60.8 Other subarachnoid haemorrhage
0.639 0.361 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.639 0.361 0.000
B35 Dermatophytosis
0.637 0.363 0.000
S01.4 Open wound of cheek and temporomandibular area
0.637 0.363 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.637 0.363 0.000
M22 Disorders of patella
0.636 0.364 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.636 0.364 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.636 0.364 0.000
M13.8 Other specified arthritis
0.635 0.364 0.000
M13.1 Monoarthritis, not elsewhere classified
0.635 0.364 0.000
T20 Burn and corrosion of head and neck
0.635 0.365 0.000
A80-A89 Viral infections of the central nervous system
0.634 0.366 0.000
M91-M94 Chondropathies
0.634 0.366 0.000
Z01.8 Other specified special examinations
0.634 0.366 0.000
D68 Other coagulation defects
0.634 0.366 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.632 0.368 0.000
S64 Injury of nerves at wrist and hand level
0.630 0.369 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.630 0.370 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.629 0.371 0.000
G82.5 Tetraplegia, unspecified
0.629 0.371 0.000
G82.3 Flaccid tetraplegia
0.629 0.371 0.000
G82.0 Flaccid paraplegia
0.629 0.371 0.000
H43 Disorders of vitreous body
0.629 0.371 0.000
E03 Other hypothyroidism
0.628 0.371 0.000
L29.0 Pruritus ani
0.628 0.372 0.000
M34 Systemic sclerosis
0.627 0.372 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.627 0.373 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.627 0.373 0.000
Y98 Lifestyle-related condition
0.627 0.373 0.000
Y97 Environmental-pollution-related condition
0.627 0.373 0.000
Y96 Work-related condition
0.627 0.373 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.627 0.373 0.000
L30.8 Other specified dermatitis
0.627 0.373 0.000
D86 Sarcoidosis
0.627 0.373 0.000
S32 Fracture of lumbar spine and pelvis
0.626 0.374 0.000
Z60 Problems related to social environment
0.625 0.375 0.000
S29 Other and unspecified injuries of thorax
0.625 0.375 0.000
S20.2 Contusion of thorax
0.625 0.375 0.000
Z65 Problems related to other psychosocial circumstances
0.624 0.375 0.000
Z64 Problems related to certain psychosocial circumstances
0.624 0.375 0.000
Z62 Other problems related to upbringing
0.624 0.375 0.000
Z61 Problems related to negative life events in childhood
0.624 0.375 0.000
Z59 Problems related to housing and economic circumstances
0.624 0.375 0.000
Z58 Problems related to physical environment
0.624 0.375 0.000
Z55 Problems related to education and literacy
0.624 0.375 0.000
I77.5 Necrosis of artery
0.624 0.376 0.000
I77.4 Coeliac artery compression syndrome
0.624 0.376 0.000
I77.3 Arterial fibromuscular dysplasia
0.624 0.376 0.000
I77.2 Rupture of artery
0.624 0.376 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.624 0.376 0.000
S08 Traumatic amputation of part of head
0.624 0.376 0.000
S07 Crushing injury of head
0.624 0.376 0.000
S04 Injury of cranial nerves
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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