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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116611433
log Bayes Factor = 11.807
Chromosome 1   position 234,277,494  (GRCh37) Explore rs116611433 on Ensembl!
Variant rs116611433 is part of Cluster X0167

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
S00-S09 Injuries to the head
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
S00 Superficial injury of head
0.994 0.006 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.993 0.007 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
I60-I69 Cerebrovascular diseases
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.987 0.013 0.000
I21 Acute myocardial infarction
0.982 0.018 0.000
C79 Secondary malignant neoplasm of other sites
0.981 0.019 0.000
Z85 Personal history of malignant neoplasm
0.980 0.020 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.978 0.022 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.976 0.024 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.976 0.024 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.975 0.025 0.000
S01 Open wound of head
0.973 0.027 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.973 0.027 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.971 0.029 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.966 0.034 0.000
C50-C50 Malignant neoplasm of breast
0.963 0.037 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.962 0.038 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.960 0.040 0.000
C78.7 Secondary malignant neoplasm of liver
0.954 0.046 0.000
I63 Cerebral infarction
0.953 0.047 0.000
L20-L30 Dermatitis and eczema
0.952 0.048 0.000
Chapter VIII Diseases of the ear and mastoid process
0.949 0.051 0.000
Chapter VII Diseases of the eye and adnexa
0.946 0.054 0.000
E00-E07 Disorders of thyroid gland
0.942 0.058 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.936 0.064 0.000
C50 Malignant neoplasm of breast
0.936 0.064 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.935 0.065 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.935 0.065 0.000
S20-S29 Injuries to the thorax
0.930 0.070 0.000
C77.3 Axillary and upper limb lymph nodes
0.930 0.070 0.000
Z92 Personal history of medical treatment
0.926 0.074 0.000
E87.6 Hypokalaemia
0.924 0.076 0.000
E87.7 Fluid overload
0.921 0.079 0.000
S00.8 Superficial injury of other parts of head
0.911 0.089 0.000
H02 Other disorders of eyelid
0.910 0.090 0.000
E86 Volume depletion
0.909 0.091 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.907 0.093 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.907 0.093 0.000
I60 Subarachnoid haemorrhage
0.901 0.099 0.000
S01.5 Open wound of lip and oral cavity
0.899 0.101 0.000
A00-A09 Intestinal infectious diseases
0.897 0.103 0.000
I61 Intracerebral haemorrhage
0.891 0.109 0.000
S00.0 Superficial injury of scalp
0.891 0.109 0.000
L30 Other dermatitis
0.890 0.109 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.886 0.114 0.000
H65-H75 Diseases of middle ear and mastoid
0.884 0.116 0.000
S00.1 Contusion of eyelid and periocular area
0.883 0.117 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.878 0.122 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.876 0.124 0.000
L29 Pruritus
0.872 0.128 0.000
L27 Dermatitis due to substances taken internally
0.866 0.134 0.000
Z90.1 Acquired absence of breast(s)
0.865 0.135 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.865 0.135 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.863 0.137 0.000
C50.9 Breast, unspecified
0.862 0.138 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.862 0.138 0.000
Z95.4 Presence of other heart-valve replacement
0.861 0.139 0.000
Z50 Care involving use of rehabilitation procedures
0.857 0.143 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.855 0.145 0.000
S60-S69 Injuries to the wrist and hand
0.855 0.145 0.000
H90-H95 Other disorders of ear
0.854 0.146 0.000
H02.4 Ptosis of eyelid
0.853 0.147 0.000
S00.3 Superficial injury of nose
0.853 0.147 0.000
S10-S19 Injuries to the neck
0.852 0.148 0.000
E87.2 Acidosis
0.850 0.150 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
L30.9 Dermatitis, unspecified
0.846 0.154 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.843 0.157 0.000
S01.8 Open wound of other parts of head
0.841 0.159 0.000
I21.9 Acute myocardial infarction, unspecified
0.839 0.161 0.000
E04 Other non-toxic goitre
0.837 0.163 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.836 0.164 0.000
I67 Other cerebrovascular diseases
0.835 0.165 0.000
W00-W19 Falls
0.833 0.167 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.832 0.168 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.831 0.169 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.830 0.170 0.000
I20 Angina pectoris
0.826 0.174 0.000
H04 Disorders of lachrymal system
0.825 0.175 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.825 0.175 0.000
S06 Intracranial injury
0.823 0.177 0.000
H02.0 Entropion and trichiasis of eyelid
0.819 0.181 0.000
I25.1 Atherosclerotic heart disease
0.817 0.183 0.000
I63.9 Cerebral infarction, unspecified
0.816 0.184 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.815 0.185 0.000
H55-H59 Other disorders of eye and adnexa
0.815 0.185 0.000
I22 Subsequent myocardial infarction
0.815 0.185 0.000
H72 Perforation of tympanic membrane
0.810 0.190 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.808 0.192 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.806 0.194 0.000
C79.2 Secondary malignant neoplasm of skin
0.805 0.195 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.805 0.195 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.805 0.195 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.805 0.195 0.000
C01 Malignant neoplasm of base of tongue
0.804 0.195 0.000
C77.5 Intrapelvic lymph nodes
0.803 0.197 0.000
I05-I09 Chronic rheumatic heart diseases
0.802 0.198 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.801 0.199 0.000
E83 Disorders of mineral metabolism
0.801 0.199 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.801 0.199 0.000
S01.1 Open wound of eyelid and periocular area
0.801 0.199 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.800 0.200 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.800 0.200 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.799 0.201 0.000
Y43 Primarily systemic agents
0.795 0.205 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.795 0.205 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.795 0.205 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.795 0.205 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.792 0.208 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.790 0.210 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.788 0.212 0.000
L50-L54 Urticaria and erythema
0.787 0.213 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.787 0.213 0.000
H05 Disorders of orbit
0.786 0.214 0.000
S01.0 Open wound of scalp
0.786 0.214 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.786 0.214 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.786 0.214 0.000
S27 Injury of other and unspecified intrathoracic organs
0.785 0.215 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.783 0.217 0.000
I24 Other acute ischaemic heart diseases
0.783 0.217 0.000
Z50.0 Cardiac rehabilitation
0.779 0.221 0.000
C64-C68 Malignant neoplasms of urinary tract
0.779 0.221 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.777 0.222 0.000
Z93 Artificial opening status
0.777 0.223 0.000
Z95.3 Presence of xenogenic heart valve
0.773 0.227 0.000
C50.2 Upper-inner quadrant of breast
0.772 0.228 0.000
X60-X84 Intentional self-harm
0.772 0.228 0.000
C50.8 Overlapping lesion of breast
0.772 0.228 0.000
Z90.8 Acquired absence of other organs
0.772 0.228 0.000
B99-B99 Other infectious diseases
0.770 0.230 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.769 0.231 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.767 0.233 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.766 0.234 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.765 0.235 0.000
H69 Other disorders of Eustachian tube
0.765 0.235 0.000
Z90.7 Acquired absence of genital organ(s)
0.764 0.236 0.000
S29 Other and unspecified injuries of thorax
0.762 0.238 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
Z42 Follow-up care involving plastic surgery
0.761 0.239 0.000
L29.9 Pruritus, unspecified
0.760 0.240 0.000
B25-B34 Other viral diseases
0.759 0.241 0.000
E40-E46 Malnutrition
0.757 0.243 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.757 0.243 0.000
Z85.6 Personal history of leukaemia
0.755 0.245 0.000
E87.3 Alkalosis
0.754 0.246 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.752 0.248 0.000
B65-B83 Helminthiases
0.752 0.248 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.752 0.248 0.000
C50.0 Nipple and areola
0.751 0.249 0.000
I67.9 Cerebrovascular disease, unspecified
0.751 0.249 0.000
E06 Thyroiditis
0.749 0.251 0.000
H66 Suppurative and unspecified otitis media
0.749 0.251 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.748 0.252 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.748 0.252 0.000
X20-X29 Contact with venomous animals and plants
0.748 0.252 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.748 0.252 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.747 0.253 0.000
S19 Other and unspecified injuries of neck
0.746 0.254 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.746 0.254 0.000
Z90.0 Acquired absence of part of head and neck
0.744 0.256 0.000
Z92.3 Personal history of irradiation
0.743 0.257 0.000
E87.5 Hyperkalaemia
0.743 0.257 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.743 0.257 0.000
Chapter V Mental and behavioural disorders
0.742 0.258 0.000
E05.9 Thyrotoxicosis, unspecified
0.742 0.258 0.000
C77.2 Intra-abdominal lymph nodes
0.742 0.258 0.000
S00.9 Superficial injury of head, part unspecified
0.742 0.258 0.000
S50-S59 Injuries to the elbow and forearm
0.741 0.259 0.000
E80.4 Gilbert's syndrome
0.740 0.260 0.000
V40-V49 Car occupant injured in transport accident
0.738 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
S01.3 Open wound of ear
0.738 0.262 0.000
L29.2 Pruritus vulvae
0.737 0.262 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.737 0.263 0.000
S01.2 Open wound of nose
0.736 0.264 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
H43-H45 Disorders of vitreous body and globe
0.735 0.265 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.734 0.266 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.733 0.267 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.733 0.267 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.732 0.268 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.731 0.269 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.729 0.271 0.000
C78.2 Secondary malignant neoplasm of pleura
0.728 0.272 0.000
H02.9 Disorder of eyelid, unspecified
0.727 0.273 0.000
C79.6 Secondary malignant neoplasm of ovary
0.727 0.273 0.000
Z72 Problems related to lifestyle
0.727 0.273 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
I20.8 Other forms of angina pectoris
0.724 0.276 0.000
Z50.8 Care involving use of rehabilitation procedures
0.724 0.276 0.000
H57 Other disorders of eye and adnexa
0.723 0.277 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.722 0.277 0.000
H02.5 Other disorders affecting eyelid function
0.722 0.278 0.000
I25.3 Aneurysm of heart
0.722 0.278 0.000
Z88.2 Personal history of allergy to sulphonamides
0.721 0.279 0.000
C50.1 Central portion of breast
0.721 0.279 0.000
X50-X57 Overexertion, travel and privation
0.721 0.279 0.000
S02 Fracture of skull and facial bones
0.721 0.279 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.720 0.280 0.000
S90-S99 Injuries to the ankle and foot
0.720 0.280 0.000
I60.8 Other subarachnoid haemorrhage
0.719 0.281 0.000
Z90.2 Acquired absence of lung [part of]
0.719 0.281 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I20.0 Unstable angina
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.716 0.283 0.000
S07 Crushing injury of head
0.716 0.283 0.000
S05 Injury of eye and orbit
0.716 0.283 0.000
S04 Injury of cranial nerves
0.716 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.715 0.285 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.713 0.287 0.000
S00.7 Multiple superficial injuries of head
0.713 0.287 0.000
S00.5 Superficial injury of lip and oral cavity
0.713 0.287 0.000
S00.4 Superficial injury of ear
0.713 0.287 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.711 0.289 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
Z52 Donors of organs and tissues
0.709 0.290 0.000
H18 Other disorders of cornea
0.708 0.292 0.000
E85 Amyloidosis
0.707 0.292 0.000
E84 Cystic fibrosis
0.707 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.707 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.707 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.707 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.707 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.707 0.292 0.000
E73 Lactose intolerance
0.707 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.707 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.707 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.707 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.707 0.292 0.000
H91 Other hearing loss
0.707 0.293 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.707 0.293 0.000
C50.3 Lower-inner quadrant of breast
0.707 0.293 0.000
H90 Conductive and sensorineural hearing loss
0.707 0.293 0.000
I63.8 Other cerebral infarction
0.706 0.294 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.704 0.296 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.704 0.296 0.000
Z92.8 Personal history of other medical treatment
0.704 0.296 0.000
S64 Injury of nerves at wrist and hand level
0.704 0.296 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.703 0.297 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.703 0.297 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.703 0.297 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.703 0.297 0.000
Z93.3 Colostomy status
0.703 0.297 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.702 0.298 0.000
I62 Other nontraumatic intracranial haemorrhage
0.701 0.299 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
I25.4 Coronary artery aneurysm
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.700 0.300 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.700 0.300 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.700 0.300 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.300 0.000
Z50.1 Other physical therapy
0.699 0.301 0.000
C77.0 Lymph nodes of head, face and neck
0.699 0.301 0.000
E87.4 Mixed disorder of acid-base balance
0.699 0.301 0.000
E83.4 Disorders of magnesium metabolism
0.698 0.302 0.000
S01.7 Multiple open wounds of head
0.698 0.302 0.000
Z74 Problems related to care-provider dependency
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.302 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.698 0.302 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
T36 Poisoning by systemic antibiotics
0.698 0.302 0.000
E04.2 Non-toxic multinodular goitre
0.696 0.304 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.695 0.305 0.000
T51 Toxic effect of alcohol
0.694 0.306 0.000
H06.2 Dysthyroid exophthalmos
0.693 0.307 0.000
C77.9 Lymph node, unspecified
0.692 0.308 0.000
E50-E64 Other nutritional deficiencies
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.691 0.309 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.690 0.310 0.000
L10-L14 Bullous disorders
0.689 0.310 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
Y00-Y09 Assault
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.689 0.311 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.689 0.311 0.000
S62 Fracture at wrist and hand level
0.689 0.311 0.000
Y40 Systemic antibiotics
0.688 0.312 0.000
C80 Malignant neoplasm without specification of site
0.688 0.312 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.687 0.312 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.313 0.000
S01.4 Open wound of cheek and temporomandibular area
0.686 0.314 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.686 0.314 0.000
E04.1 Non-toxic single thyroid nodule
0.685 0.315 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.685 0.315 0.000
W08 Fall involving other furniture
0.684 0.316 0.000
I05 Rheumatic mitral valve diseases
0.684 0.316 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.683 0.317 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.683 0.317 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.683 0.317 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.683 0.317 0.000
L25 Unspecified contact dermatitis
0.683 0.317 0.000
L24 Irritant contact dermatitis
0.683 0.317 0.000
L23 Allergic contact dermatitis
0.683 0.317 0.000
L21 Seborrhoeic dermatitis
0.683 0.317 0.000
L20 Atopic dermatitis
0.683 0.317 0.000
L26 Exfoliative dermatitis
0.683 0.317 0.000
L22 Diaper [napkin] dermatitis
0.683 0.317 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.682 0.318 0.000
Z72.1 Alcohol use
0.680 0.320 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.679 0.321 0.000
W20-W49 Exposure to inanimate mechanical forces
0.679 0.321 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.678 0.322 0.000
Z50.5 Speech therapy
0.678 0.322 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.678 0.322 0.000
D69 Purpura and other haemorrhagic conditions
0.677 0.323 0.000
D00-D09 In situ neoplasms
0.676 0.324 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.675 0.325 0.000
E00 Congenital iodine-deficiency syndrome
0.675 0.325 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.675 0.325 0.000
H02.3 Blepharochalasis
0.675 0.325 0.000
Z75 Problems related to medical facilities and other health care
0.674 0.325 0.000
H66.9 Otitis media, unspecified
0.674 0.326 0.000
Chapter XI Diseases of the digestive system
0.673 0.327 0.000
Z95.0 Presence of cardiac pacemaker
0.673 0.327 0.000
E07 Other disorders of thyroid
0.672 0.328 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
B50-B64 Protozoal diseases
0.672 0.328 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.671 0.329 0.000
C50.6 Axillary tail of breast
0.671 0.329 0.000
S19.9 Unspecified injury of neck
0.671 0.329 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
C50.4 Upper-outer quadrant of breast
0.670 0.330 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.669 0.331 0.000
Z97 Presence of other devices
0.669 0.331 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.667 0.333 0.000
S26 Injury of heart
0.667 0.333 0.000
S25 Injury of blood vessels of thorax
0.667 0.333 0.000
S24 Injury of nerves and spinal cord at thorax level
0.667 0.333 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.667 0.333 0.000
S21 Open wound of thorax
0.667 0.333 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.667 0.333 0.000
H74 Other disorders of middle ear and mastoid
0.665 0.334 0.000
S06.4 Epidural haemorrhage
0.664 0.335 0.000
S65 Injury of blood vessels at wrist and hand level
0.664 0.335 0.000
Z92.9 Personal history of medical treatment, unspecified
0.664 0.336 0.000
Z92.5 Personal history of rehabilitation measures
0.664 0.336 0.000
Z80 Family history of malignant neoplasm
0.663 0.337 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.662 0.338 0.000
Z90.5 Acquired absence of kidney
0.662 0.338 0.000
Z90.3 Acquired absence of part of stomach
0.662 0.338 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.661 0.339 0.000
S69 Other and unspecified injuries of wrist and hand
0.660 0.340 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.660 0.340 0.000
T98 Sequelae of other and unspecified effects of external causes
0.660 0.340 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.341 0.000
C09 Malignant neoplasm of tonsil
0.659 0.341 0.000
E87.0 Hyperosmolality and hypernatraemia
0.656 0.343 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.655 0.344 0.000
C78.0 Secondary malignant neoplasm of lung
0.654 0.346 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.654 0.346 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.653 0.347 0.000
H02.2 Lagophthalmos
0.653 0.347 0.000
Y52 Agents primarily affecting the cardiovascular system
0.652 0.348 0.000
K55-K64 Other diseases of intestines
0.651 0.349 0.000
B99 Other and unspecified infectious diseases
0.651 0.349 0.000
Y59 Other and unspecified vaccines and biological substances
0.650 0.350 0.000
Y58 Bacterial vaccines
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.650 0.350 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.650 0.350 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.650 0.350 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.650 0.350 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.650 0.350 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.650 0.350 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.650 0.350 0.000
C13 Malignant neoplasm of hypopharynx
0.650 0.350 0.000
C11 Malignant neoplasm of nasopharynx
0.650 0.350 0.000
C10 Malignant neoplasm of oropharynx
0.650 0.350 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.650 0.350 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.650 0.350 0.000
C05 Malignant neoplasm of palate
0.650 0.350 0.000
C04 Malignant neoplasm of floor of mouth
0.650 0.350 0.000
C03 Malignant neoplasm of gum
0.650 0.350 0.000
C00 Malignant neoplasm of lip
0.650 0.350 0.000
C12 Malignant neoplasm of pyriform sinus
0.650 0.350 0.000
C07 Malignant neoplasm of parotid gland
0.650 0.350 0.000
L28 Lichen simplex chronicus and prurigo
0.650 0.350 0.000
Y57 Other and unspecified drugs and medicaments
0.648 0.352 0.000
B35-B49 Mycoses
0.647 0.353 0.000
C15-C26 Malignant neoplasms of digestive organs
0.647 0.353 0.000
H73 Other disorders of tympanic membrane
0.646 0.354 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.646 0.354 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.646 0.354 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.646 0.354 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.646 0.354 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.646 0.354 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.646 0.354 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.646 0.354 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.646 0.354 0.000
T46.1 Calcium-channel blockers
0.645 0.355 0.000
H21 Other disorders of iris and ciliary body
0.644 0.356 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.644 0.356 0.000
Y43.3 Other antineoplastic drugs
0.644 0.356 0.000
H16 Keratitis
0.644 0.356 0.000
Z40 Prophylactic surgery
0.643 0.357 0.000
H92 Otalgia and effusion of ear
0.643 0.357 0.000
S22.5 Flail chest
0.643 0.357 0.000
A07 Other protozoal intestinal diseases
0.643 0.357 0.000
A06 Amoebiasis
0.643 0.357 0.000
A05 Other bacterial foodborne intoxications
0.643 0.357 0.000
A03 Shigellosis
0.643 0.357 0.000
A02 Other Salmonella infections
0.643 0.357 0.000
A01 Typhoid and paratyphoid fevers
0.643 0.357 0.000
A00 Cholera
0.643 0.357 0.000
Y43.1 Antineoplastic antimetabolites
0.643 0.357 0.000
Chapter XXII Codes for special purposes
0.642 0.358 0.000
S29.9 Unspecified injury of thorax
0.642 0.358 0.000
E04.9 Non-toxic goitre, unspecified
0.642 0.358 0.000
W06 Fall involving bed
0.641 0.359 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.641 0.359 0.000
Y45.1 Salicylates
0.641 0.359 0.000
H93 Other disorders of ear, not elsewhere classified
0.641 0.359 0.000
K90-K93 Other diseases of the digestive system
0.640 0.360 0.000
K59 Other functional intestinal disorders
0.640 0.360 0.000
I61.8 Other intracerebral haemorrhage
0.639 0.361 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.639 0.361 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.639 0.361 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.639 0.361 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.639 0.361 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.639 0.361 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.639 0.361 0.000
D68 Other coagulation defects
0.639 0.361 0.000
H05.0 Acute inflammation of orbit
0.639 0.361 0.000
S27.0 Traumatic pneumothorax
0.639 0.361 0.000
L30.8 Other specified dermatitis
0.638 0.361 0.000
L30.5 Pityriasis alba
0.638 0.361 0.000
L30.4 Erythema intertrigo
0.638 0.361 0.000
L30.3 Infective dermatitis
0.638 0.361 0.000
L30.2 Cutaneous autosensitisation
0.638 0.361 0.000
L30.1 Dyshidrosis [pompholyx]
0.638 0.361 0.000
L30.0 Nummular dermatitis
0.638 0.361 0.000
L29.0 Pruritus ani
0.638 0.362 0.000
I22.8 Subsequent myocardial infarction of other sites
0.638 0.362 0.000
T40.2 Other opioids
0.637 0.363 0.000
A80-A89 Viral infections of the central nervous system
0.636 0.364 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.636 0.364 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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