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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116879316
log Bayes Factor = 13.0202
Chromosome 11   position 24,123,914  (GRCh37) Explore rs116879316 on Ensembl!
Variant rs116879316 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J30-J39 Other diseases of upper respiratory tract
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
J34 Other disorders of nose and nasal sinuses
0.991 0.009 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.990 0.010 0.000
M50-M54 Other dorsopathies
0.987 0.013 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.986 0.014 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.984 0.016 0.000
M54 Dorsalgia
0.980 0.020 0.000
Z92 Personal history of medical treatment
0.979 0.021 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.973 0.027 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.970 0.030 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.969 0.031 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.967 0.033 0.000
N25-N29 Other disorders of kidney and ureter
0.964 0.036 0.000
M54.5 Low back pain
0.962 0.038 0.000
J34.3 Hypertrophy of nasal turbinates
0.960 0.040 0.000
M25 Other joint disorders, not elsewhere classified
0.959 0.041 0.000
N60-N64 Disorders of breast
0.959 0.041 0.000
M80-M85 Disorders of bone density and structure
0.957 0.043 0.000
Z80 Family history of malignant neoplasm
0.957 0.043 0.000
M45-M49 Spondylopathies
0.952 0.048 0.000
Chapter II Neoplasms
0.943 0.057 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.939 0.061 0.000
M20 Acquired deformities of fingers and toes
0.939 0.061 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.938 0.062 0.000
N10-N16 Renal tubulo-interstitial diseases
0.936 0.064 0.000
Z91.6 Personal history of other physical trauma
0.936 0.064 0.000
N99-N99 Other disorders of the genitourinary system
0.932 0.068 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.922 0.078 0.000
L82 Seborrhoeic keratosis
0.920 0.080 0.000
M81 Osteoporosis without pathological fracture
0.916 0.084 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.915 0.085 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.914 0.086 0.000
Z97 Presence of other devices
0.904 0.096 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.899 0.101 0.000
C43 Malignant melanoma of skin
0.899 0.101 0.000
Chapter XI Diseases of the digestive system
0.899 0.101 0.000
M25.7 Osteophyte
0.897 0.103 0.000
J34.2 Deviated nasal septum
0.897 0.103 0.000
M54.59 Low back pain (Site unspecified)
0.896 0.104 0.000
N62 Hypertrophy of breast
0.895 0.105 0.000
J40-J47 Chronic lower respiratory diseases
0.891 0.109 0.000
M54.57 Low back pain (Lumbosacral region)
0.891 0.109 0.000
N63 Unspecified lump in breast
0.889 0.111 0.000
M81.9 Osteoporosis, unspecified
0.887 0.113 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.887 0.113 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.885 0.115 0.000
C43.5 Malignant melanoma of trunk
0.885 0.115 0.000
Chapter VIII Diseases of the ear and mastoid process
0.885 0.115 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.881 0.119 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.880 0.120 0.000
D68 Other coagulation defects
0.877 0.123 0.000
K70-K77 Diseases of liver
0.876 0.124 0.000
Z85 Personal history of malignant neoplasm
0.875 0.125 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.869 0.131 0.000
M24 Other specific joint derangements
0.869 0.131 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.861 0.139 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.860 0.140 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.857 0.143 0.000
M45 Ankylosing spondylitis
0.856 0.144 0.000
T66-T78 Other and unspecified effects of external causes
0.855 0.145 0.000
M21 Other acquired deformities of limbs
0.851 0.149 0.000
J30 Vasomotor and allergic rhinitis
0.850 0.150 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.847 0.153 0.000
M20.4 Other hammer toe(s) (acquired)
0.846 0.154 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.846 0.154 0.000
J32 Chronic sinusitis
0.845 0.155 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.843 0.157 0.000
L40-L45 Papulosquamous disorders
0.842 0.158 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.842 0.158 0.000
J39 Other diseases of upper respiratory tract
0.840 0.160 0.000
Z83 Family history of other specific disorders
0.838 0.162 0.000
M25.76 Osteophyte (Lower leg)
0.835 0.165 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.834 0.166 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.834 0.166 0.000
Z91.5 Personal history of self-harm
0.831 0.169 0.000
M47 Spondylosis
0.830 0.170 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.830 0.170 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.829 0.171 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.828 0.172 0.000
M25.8 Other specified joint disorders
0.827 0.173 0.000
L20-L30 Dermatitis and eczema
0.825 0.175 0.000
L91 Hypertrophic disorders of skin
0.823 0.177 0.000
K76 Other diseases of liver
0.823 0.177 0.000
J44 Other chronic obstructive pulmonary disease
0.822 0.178 0.000
N10 Acute tubulo-interstitial nephritis
0.821 0.179 0.000
J95-J99 Other diseases of the respiratory system
0.821 0.179 0.000
Z97.8 Presence of other specified devices
0.818 0.182 0.000
M54.3 Sciatica
0.818 0.182 0.000
C50-C50 Malignant neoplasm of breast
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.816 0.184 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.815 0.185 0.000
S80-S89 Injuries to the knee and lower leg
0.815 0.185 0.000
D80-D89 Certain disorders involving the immune mechanism
0.812 0.188 0.000
N28.8 Other specified disorders of kidney and ureter
0.810 0.190 0.000
J33 Nasal polyp
0.807 0.193 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.806 0.194 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.804 0.196 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.802 0.197 0.000
Z47 Other orthopaedic follow-up care
0.801 0.199 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.801 0.199 0.000
M31 Other necrotising vasculopathies
0.801 0.199 0.000
M05-M14 Inflammatory polyarthropathies
0.798 0.202 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.795 0.205 0.000
N30-N39 Other diseases of urinary system
0.794 0.206 0.000
D69 Purpura and other haemorrhagic conditions
0.793 0.207 0.000
Z72 Problems related to lifestyle
0.788 0.212 0.000
M54.9 Dorsalgia, unspecified
0.787 0.212 0.000
M20.5 Other deformities of toe(s) (acquired)
0.786 0.214 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.785 0.215 0.000
L81 Other disorders of pigmentation
0.784 0.215 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.783 0.217 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.782 0.218 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.781 0.219 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.779 0.221 0.000
J45 Asthma
0.779 0.221 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.778 0.221 0.000
L40 Psoriasis
0.778 0.222 0.000
G40-G47 Episodic and paroxysmal disorders
0.778 0.222 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.777 0.223 0.000
G70-G73 Diseases of myoneural junction and muscle
0.775 0.225 0.000
Z92.0 Personal history of contraception
0.774 0.226 0.000
T78 Adverse effects, not elsewhere classified
0.773 0.227 0.000
D68.8 Other specified coagulation defects
0.773 0.227 0.000
Z97.4 Presence of external hearing-aid
0.772 0.228 0.000
M91-M94 Chondropathies
0.771 0.229 0.000
M23 Internal derangement of knee
0.771 0.229 0.000
Z90.1 Acquired absence of breast(s)
0.768 0.232 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.768 0.232 0.000
N32 Other disorders of bladder
0.768 0.232 0.000
D55-D59 Haemolytic anaemias
0.766 0.234 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.764 0.236 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.763 0.237 0.000
N73 Other female pelvic inflammatory diseases
0.763 0.237 0.000
Z72.1 Alcohol use
0.762 0.238 0.000
M25.4 Effusion of joint
0.762 0.238 0.000
J60-J70 Lung diseases due to external agents
0.761 0.239 0.000
M54.4 Lumbago with sciatica
0.759 0.241 0.000
N28.1 Cyst of kidney, acquired
0.758 0.242 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.758 0.242 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.758 0.242 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.756 0.244 0.000
K50-K52 Noninfective enteritis and colitis
0.756 0.244 0.000
C44 Other malignant neoplasms of skin
0.755 0.245 0.000
M80 Osteoporosis with pathological fracture
0.754 0.246 0.000
K40-K46 Hernia
0.754 0.246 0.000
M24.1 Other articular cartilage disorders
0.752 0.248 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.749 0.251 0.000
K75 Other inflammatory liver diseases
0.748 0.252 0.000
M48 Other spondylopathies
0.748 0.252 0.000
N32.0 Bladder-neck obstruction
0.748 0.252 0.000
D60-D64 Aplastic and other anaemias
0.747 0.253 0.000
M20.1 Hallux valgus (acquired)
0.747 0.253 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.746 0.254 0.000
H65-H75 Diseases of middle ear and mastoid
0.746 0.254 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.746 0.254 0.000
Chapter IX Diseases of the circulatory system
0.746 0.254 0.000
M86-M90 Other osteopathies
0.742 0.258 0.000
M54.39 Sciatica (Site unspecified)
0.742 0.258 0.000
K74 Fibrosis and cirrhosis of liver
0.742 0.258 0.000
D37.4 Colon
0.741 0.259 0.000
M54.2 Cervicalgia
0.741 0.259 0.000
M53 Other dorsopathies, not elsewhere classified
0.741 0.259 0.000
J39.2 Other diseases of pharynx
0.740 0.260 0.000
M47.9 Spondylosis, unspecified
0.740 0.260 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.738 0.262 0.000
G57 Mononeuropathies of lower limb
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.737 0.263 0.000
D73 Diseases of spleen
0.736 0.264 0.000
C43.9 Malignant melanoma of skin, unspecified
0.733 0.266 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.733 0.267 0.000
G20-G26 Extrapyramidal and movement disorders
0.733 0.267 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.732 0.268 0.000
M25.86 Other specified joint disorders (Lower leg)
0.732 0.268 0.000
L83 Acanthosis nigricans
0.731 0.269 0.000
N70 Salpingitis and oophoritis
0.729 0.271 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.729 0.271 0.000
C50 Malignant neoplasm of breast
0.728 0.272 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.728 0.272 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.728 0.272 0.000
L90 Atrophic disorders of skin
0.727 0.273 0.000
M25.3 Other instability of joint
0.726 0.274 0.000
S10-S19 Injuries to the neck
0.726 0.274 0.000
H80-H83 Diseases of inner ear
0.726 0.274 0.000
D68.9 Coagulation defect, unspecified
0.726 0.274 0.000
J45.9 Asthma, unspecified
0.725 0.275 0.000
M35 Other systemic involvement of connective tissue
0.724 0.276 0.000
M54.1 Radiculopathy
0.724 0.276 0.000
D75 Other diseases of blood and blood-forming organs
0.722 0.278 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.721 0.279 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.721 0.279 0.000
G81 Hemiplegia
0.721 0.279 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.720 0.280 0.000
N72 Inflammatory disease of cervix uteri
0.718 0.282 0.000
M34 Systemic sclerosis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Z98 Other postsurgical states
0.716 0.284 0.000
J37 Chronic laryngitis and laryngotracheitis
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.284 0.000
M33 Dermatopolymyositis
0.715 0.284 0.000
M32 Systemic lupus erythematosus
0.715 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.284 0.000
Chapter VII Diseases of the eye and adnexa
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
J30.1 Allergic rhinitis due to pollen
0.714 0.286 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.714 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.713 0.287 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.713 0.287 0.000
I30-I52 Other forms of heart disease
0.713 0.287 0.000
L91.8 Other hypertrophic disorders of skin
0.712 0.288 0.000
Z92.8 Personal history of other medical treatment
0.712 0.288 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.711 0.289 0.000
J36 Peritonsillar abscess
0.710 0.290 0.000
Z84 Family history of other conditions
0.710 0.290 0.000
Z81 Family history of mental and behavioural disorders
0.710 0.290 0.000
D37.5 Rectum
0.707 0.293 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.707 0.293 0.000
S00-S09 Injuries to the head
0.707 0.293 0.000
K81 Cholecystitis
0.706 0.294 0.000
Z41 Procedures for purposes other than remedying health state
0.706 0.294 0.000
M54.6 Pain in thoracic spine
0.705 0.294 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
K50 Crohn's disease [regional enteritis]
0.704 0.296 0.000
D68.2 Hereditary deficiency of other clotting factors
0.704 0.296 0.000
Z83.7 Family history of diseases of the digestive system
0.704 0.296 0.000
M54.8 Other dorsalgia
0.703 0.297 0.000
M54.0 Panniculitis affecting regions of neck and back
0.703 0.297 0.000
G30-G32 Other degenerative diseases of the nervous system
0.703 0.297 0.000
N76 Other inflammation of vagina and vulva
0.703 0.297 0.000
N99.5 Malfunction of external stoma of urinary tract
0.702 0.298 0.000
Z89 Acquired absence of limb
0.702 0.298 0.000
Z92.9 Personal history of medical treatment, unspecified
0.702 0.298 0.000
Z92.5 Personal history of rehabilitation measures
0.702 0.298 0.000
M84 Disorders of continuity of bone
0.702 0.298 0.000
Chapter XX External causes of morbidity and mortality
0.702 0.298 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.701 0.299 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.701 0.299 0.000
M50 Cervical disk disorders
0.700 0.300 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.700 0.300 0.000
T78.3 Angioneurotic oedema
0.698 0.302 0.000
H90-H95 Other disorders of ear
0.698 0.302 0.000
S20-S29 Injuries to the thorax
0.697 0.302 0.000
G90-G99 Other disorders of the nervous system
0.697 0.303 0.000
L40.0 Psoriasis vulgaris
0.696 0.304 0.000
J42 Unspecified chronic bronchitis
0.696 0.304 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.695 0.305 0.000
Z91.7 Personal history of female genital mutilation
0.695 0.305 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.695 0.305 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.695 0.305 0.000
Z91.2 Personal history of poor personal hygiene
0.695 0.305 0.000
T33-T35 Frostbite
0.695 0.305 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.695 0.305 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
T00-T07 Injuries involving multiple body regions
0.695 0.305 0.000
J32.2 Chronic ethmoidal sinusitis
0.695 0.305 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.693 0.307 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.693 0.307 0.000
L94 Other localised connective tissue disorders
0.693 0.307 0.000
L93 Lupus erythematosus
0.693 0.307 0.000
L87 Transepidermal elimination disorders
0.693 0.307 0.000
L88 Pyoderma gangrenosum
0.693 0.307 0.000
L86 Keratoderma in diseases classified elsewhere
0.693 0.307 0.000
L80 Vitiligo
0.693 0.307 0.000
K76.9 Liver disease, unspecified
0.692 0.308 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.691 0.309 0.000
N27 Small kidney of unknown cause
0.691 0.309 0.000
N25 Disorders resulting from impaired renal tubular function
0.691 0.309 0.000
N26 Unspecified contracted kidney
0.691 0.309 0.000
N99.0 Postprocedural renal failure
0.691 0.309 0.000
G47 Sleep disorders
0.691 0.309 0.000
K41 Femoral hernia
0.690 0.309 0.000
M65-M68 Disorders of synovium and tendon
0.690 0.310 0.000
D86 Sarcoidosis
0.690 0.310 0.000
M21.1 Varus deformity, not elsewhere classified
0.690 0.310 0.000
M54.55 Low back pain (Thoracolumbar region)
0.690 0.310 0.000
M54.54 Low back pain-Thoracic
0.690 0.310 0.000
M54.53 Low back pain-Cervicothoracic
0.690 0.310 0.000
M54.52 Low back pain-Cervical
0.690 0.310 0.000
M54.51 Low back pain-Occipit-atl-axl
0.690 0.310 0.000
M54.50 Low back pain (Multiple sites in spine)
0.690 0.310 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.689 0.311 0.000
M25.9 Joint disorder, unspecified
0.687 0.312 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.687 0.312 0.000
M25.2 Flail joint
0.687 0.312 0.000
M25.1 Fistula of joint
0.687 0.312 0.000
M25.0 Haemarthrosis
0.687 0.312 0.000
S50-S59 Injuries to the elbow and forearm
0.687 0.313 0.000
M21.4 Flat foot [pes planus] (acquired)
0.686 0.314 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.686 0.314 0.000
M83 Adult osteomalacia
0.686 0.314 0.000
M82 Osteoporosis in diseases classified elsewhere
0.686 0.314 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.686 0.314 0.000
Z80.6 Family history of leukaemia
0.686 0.314 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.686 0.314 0.000
M25.74 Osteophyte (Hand)
0.686 0.314 0.000
J31.0 Chronic rhinitis
0.685 0.315 0.000
T90 Sequelae of injuries of head
0.684 0.316 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.683 0.317 0.000
Chapter XXII Codes for special purposes
0.683 0.317 0.000
L92.0 Granuloma annulare
0.682 0.318 0.000
D38.1 Trachea, bronchus and lung
0.682 0.318 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.681 0.319 0.000
M25.78 Osteophyte (Other)
0.681 0.319 0.000
N75 Diseases of Bartholin's gland
0.681 0.319 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.679 0.320 0.000
N64 Other disorders of breast
0.679 0.321 0.000
G82 Paraplegia and tetraplegia
0.679 0.321 0.000
G57.6 Lesion of plantar nerve
0.679 0.321 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.678 0.322 0.000
Z42 Follow-up care involving plastic surgery
0.678 0.322 0.000
O60-O75 Complications of labour and delivery
0.678 0.322 0.000
C44.5 Skin of trunk
0.677 0.323 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.676 0.324 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.676 0.324 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.676 0.324 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.676 0.324 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.675 0.324 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.674 0.326 0.000
I49 Other cardiac arrhythmias
0.674 0.326 0.000
J33.9 Nasal polyp, unspecified
0.674 0.326 0.000
N28.0 Ischaemia and infarction of kidney
0.674 0.326 0.000
D67 Hereditary factor IX deficiency
0.673 0.327 0.000
D66 Hereditary factor VIII deficiency
0.673 0.327 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.673 0.327 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.673 0.327 0.000
M25.77 Osteophyte (Ankle and foot)
0.672 0.328 0.000
M46 Other inflammatory spondylopathies
0.672 0.328 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.671 0.328 0.000
N15 Other renal tubulo-interstitial diseases
0.671 0.328 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.671 0.328 0.000
N11 Chronic tubulo-interstitial nephritis
0.671 0.328 0.000
T86 Failure and rejection of transplanted organs and tissues
0.671 0.329 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.671 0.329 0.000
L28 Lichen simplex chronicus and prurigo
0.671 0.329 0.000
G83 Other paralytic syndromes
0.670 0.330 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.669 0.331 0.000
Z43 Attention to artificial openings
0.668 0.332 0.000
Chapter I Certain infectious and parasitic diseases
0.667 0.333 0.000
M85 Other disorders of bone density and structure
0.667 0.333 0.000
Chapter V Mental and behavioural disorders
0.667 0.333 0.000
Q50-Q56 Congenital malformations of genital organs
0.664 0.336 0.000
I60-I69 Cerebrovascular diseases
0.664 0.336 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.663 0.337 0.000
J33.8 Other polyp of sinus
0.663 0.337 0.000
J30.4 Allergic rhinitis, unspecified
0.663 0.337 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.663 0.337 0.000
G47.9 Sleep disorder, unspecified
0.663 0.337 0.000
D50-D53 Nutritional anaemias
0.662 0.337 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.662 0.338 0.000
L85 Other epidermal thickening
0.662 0.338 0.000
M31.6 Other giant cell arteritis
0.662 0.338 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.662 0.338 0.000
L84 Corns and callosities
0.661 0.338 0.000
J32.8 Other chronic sinusitis
0.661 0.339 0.000
Z74 Problems related to care-provider dependency
0.661 0.339 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.661 0.339 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.661 0.339 0.000
L27 Dermatitis due to substances taken internally
0.660 0.340 0.000
S82 Fracture of lower leg, including ankle
0.660 0.340 0.000
K35-K38 Diseases of appendix
0.660 0.340 0.000
G43 Migraine
0.659 0.341 0.000
J86 Pyothorax
0.659 0.341 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.658 0.342 0.000
M81.8 Other osteoporosis
0.657 0.343 0.000
M81.6 Localised osteoporosis [Lequesne]
0.657 0.343 0.000
M81.5 Idiopathic osteoporosis
0.657 0.343 0.000
M81.4 Drug-induced osteoporosis
0.657 0.343 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.657 0.343 0.000
M81.2 Osteoporosis of disuse
0.657 0.343 0.000
M81.1 Postoophorectomy osteoporosis
0.657 0.343 0.000
M81.0 Postmenopausal osteoporosis
0.657 0.343 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.656 0.344 0.000
I47 Paroxysmal tachycardia
0.656 0.344 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.655 0.345 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.655 0.345 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.655 0.345 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.655 0.345 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.655 0.345 0.000
D37.7 Other digestive organs
0.654 0.345 0.000
L81.9 Disorder of pigmentation, unspecified
0.653 0.347 0.000
I05-I09 Chronic rheumatic heart diseases
0.653 0.347 0.000
K81.9 Cholecystitis, unspecified
0.653 0.347 0.000
J32.0 Chronic maxillary sinusitis
0.652 0.348 0.000
I49.9 Cardiac arrhythmia, unspecified
0.651 0.349 0.000
K76.6 Portal hypertension
0.651 0.349 0.000
J32.4 Chronic pansinusitis
0.650 0.350 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.650 0.350 0.000
D72 Other disorders of white blood cells
0.650 0.350 0.000
K72 Hepatic failure, not elsewhere classified
0.650 0.350 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.650 0.350 0.000
M20.3 Other deformity of hallux (acquired)
0.649 0.351 0.000
M21.6 Other acquired deformities of ankle and foot
0.648 0.352 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.648 0.352 0.000
Z97.3 Presence of spectacles and contact lenses
0.648 0.352 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.648 0.352 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.648 0.352 0.000
Z97.0 Presence of artificial eye
0.648 0.352 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.648 0.352 0.000
G58 Other mononeuropathies
0.647 0.353 0.000
D73.0 Hyposplenism
0.646 0.354 0.000
J40 Bronchitis, not specified as acute or chronic
0.646 0.354 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.646 0.354 0.000
G56 Mononeuropathies of upper limb
0.646 0.354 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.645 0.355 0.000
C43.8 Overlapping malignant melanoma of skin
0.644 0.355 0.000
C43.4 Malignant melanoma of scalp and neck
0.644 0.355 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.644 0.355 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.644 0.355 0.000
C43.0 Malignant melanoma of lip
0.644 0.355 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.644 0.356 0.000
K65-K67 Diseases of peritoneum
0.644 0.356 0.000
M06 Other rheumatoid arthritis
0.644 0.356 0.000
M25.79 Osteophyte (Site unspecified)
0.643 0.357 0.000
M25.73 Osteophyte (Forearm)
0.643 0.357 0.000
M25.72 Osteophyte (Upper arm)
0.643 0.357 0.000
M25.71 Osteophyte (Shoulder region)
0.643 0.357 0.000
M25.70 Osteophyte (Multiple sites)
0.643 0.357 0.000
Z52 Donors of organs and tissues
0.643 0.357 0.000
T93 Sequelae of injuries of lower limb
0.642 0.358 0.000
D62 Acute posthaemorrhagic anaemia
0.641 0.359 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.641 0.359 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.640 0.360 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.640 0.360 0.000
J41 Simple and mucopurulent chronic bronchitis
0.639 0.361 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.639 0.361 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.638 0.362 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
Z83.5 Family history of eye and ear disorders
0.636 0.364 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.636 0.364 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.636 0.364 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.636 0.364 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.636 0.364 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.636 0.364 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.636 0.364 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.636 0.364 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.636 0.364 0.000
K42 Umbilical hernia
0.635 0.365 0.000
J38.4 Oedema of larynx
0.635 0.365 0.000
T78.4 Allergy, unspecified
0.635 0.365 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.634 0.365 0.000
N99.2 Postprocedural adhesions of vagina
0.634 0.365 0.000
N99.1 Postprocedural urethral stricture
0.634 0.365 0.000
Z98.1 Arthrodesis status
0.634 0.366 0.000
S80 Superficial injury of lower leg
0.633 0.367 0.000
H74 Other disorders of middle ear and mastoid
0.633 0.367 0.000
N71 Inflammatory disease of uterus, except cervix
0.632 0.368 0.000
J98 Other respiratory disorders
0.631 0.369 0.000
Z76 Persons encountering health services in other circumstances
0.631 0.369 0.000
Z73 Problems related to life-management difficulty
0.631 0.369 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.631 0.369 0.000
J00-J06 Acute upper respiratory infections
0.629 0.371 0.000
D68.6 Other Thrombophilia
0.629 0.371 0.000
D68.5 Primary Thrombophilia
0.629 0.371 0.000
D68.4 Acquired coagulation factor deficiency
0.629 0.371 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.629 0.371 0.000
D68.1 Hereditary factor XI deficiency
0.629 0.371 0.000
D68.0 Von Willebrand's disease
0.629 0.371 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.628 0.372 0.000
K83 Other diseases of biliary tract
0.628 0.372 0.000
K77 Liver disorders in diseases classified elsewhere
0.628 0.372 0.000
K73 Chronic hepatitis, not elsewhere classified
0.628 0.372 0.000
K71 Toxic liver disease
0.628 0.372 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.628 0.372 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.627 0.373 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.627 0.373 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.627 0.373 0.000
D69.5 Secondary thrombocytopenia
0.627 0.373 0.000
N32.1 Vesicointestinal fistula
0.626 0.373 0.000
I38 Endocarditis, valve unspecified
0.625 0.375 0.000
N00-N08 Glomerular diseases
0.624 0.375 0.000
T31 Burns classified according to extent of body surface involved
0.624 0.376 0.000
K75.4 Autoimmune hepatitis
0.623 0.377 0.000
M24.9 Joint derangement, unspecified
0.623 0.377 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.623 0.377 0.000
M24.7 Protrusio acetabuli
0.623 0.377 0.000
M24.6 Ankylosis of joint
0.623 0.377 0.000
M24.5 Contracture of joint
0.623 0.377 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.623 0.377 0.000
M24.2 Disorder of ligament
0.623 0.377 0.000
M24.0 Loose body in joint
0.623 0.377 0.000
T81 Complications of procedures, not elsewhere classified
0.623 0.377 0.000
M07 Psoriatic and enteropathic arthropathies
0.622 0.378 0.000
M47.2 Other spondylosis with radiculopathy
0.622 0.378 0.000
K74.3 Primary biliary cirrhosis
0.621 0.379 0.000
G81.9 Hemiplegia, unspecified
0.620 0.380 0.000
M35.0 Sicca syndrome [Sjogren]
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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